Vital Signs Listing

Listing of Vital Signs by Subject and Parameter

Setup

See Prerequisites for installation instructions.

library(arframe)
library(pharmaverseadam)
library(dplyr, warn.conflicts = FALSE)

arm_levels <- c("Placebo", "Xanomeline Low Dose", "Xanomeline High Dose")

# On-treatment vital sign records; exclude derived DTYPE rows
vs_listing <- pharmaverseadam::advs |>
  blank_to_na() |>
  filter(
    ONTRTFL == "Y",
    TRT01A %in% arm_levels,
    is.na(DTYPE)           # exclude derived records (e.g., LOCF)
  ) |>
  mutate(
    TRT01A  = factor(TRT01A, levels = arm_levels),
    PARAMCD = factor(PARAMCD),
    # Format numeric columns to 1 decimal place
    AVAL_C  = sprintf("%.1f", AVAL),
    BASE_C  = if_else(is.na(BASE), NA_character_, sprintf("%.1f", BASE)),
    CHG_C   = if_else(is.na(CHG),  NA_character_, sprintf("%.1f", CHG))
  ) |>
  arrange(PARAMCD, TRT01A, USUBJID, AVISITN) |>
  select(
    PARAMCD,
    PARAM,
    TRT01A,
    USUBJID,
    AVISIT,
    AVAL_C,
    BASE_C,
    CHG_C
  )

arframe Pipeline

vs_listing |>
  fr_table() |>
  fr_titles(
    "Listing 16.2.8.1",
    "Listing of Vital Signs by Parameter",
    "Safety Population \u2014 On-Treatment Records"
  ) |>
  fr_cols(
    PARAMCD = fr_col(visible = FALSE),
    PARAM   = fr_col(visible = FALSE),
    TRT01A  = fr_col("Treatment",    width = 2.2),
    USUBJID = fr_col("Subject ID",   width = 1.3),
    AVISIT  = fr_col("Visit",        width = 1.6),
    AVAL_C  = fr_col("Value",        width = 0.9, align = "decimal"),
    BASE_C  = fr_col("Baseline",     width = 0.9, align = "decimal"),
    CHG_C   = fr_col("Change from\nBaseline", width = 1.0, align = "decimal")
  ) |>
  fr_header(bold = TRUE, align = "center") |>
  fr_rows(page_by = "PARAMCD", sort_by = c("USUBJID", "AVISIT"), suppress = "USUBJID") |>
  fr_footnotes(
    "On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.",
    "Value, Baseline, and Change from Baseline are in original units (VSSTRESU).",
    "Sorted by parameter, treatment arm, subject, and visit number.",
    "Parameters: BMI (kg/m{fr_super(2)}), BSA (m{fr_super(2)}), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP ({fr_super(\"\u00b0\")}C), WEIGHT (kg)."
  )

Rendered Listing

Pages are separated by PARAMCD – each vital sign parameter gets its own page block. Within each parameter, records are sorted by treatment arm, subject, and visit.

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

BMI

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo	01-701-1015	Week 12	24.5	25.1	-0.6
Placebo		Week 16	24.5	25.1	-0.6
Placebo		Week 2	24.5	25.1	-0.6
Placebo		Week 20	24.5	25.1	-0.6
Placebo		Week 24	24.5	25.1	-0.6
Placebo		Week 26	24.7	25.1	-0.4
Placebo		Week 4	24.9	25.1	-0.2
Placebo		Week 6	24.5	25.1	-0.6
Placebo		Week 8	24.5	25.1	-0.6
Placebo	01-701-1023	Week 2	30.6	30.4	0.2
Xanomeline High Dose	01-701-1028	Week 12	31.3	31.4	-0.1
Xanomeline High Dose		Week 16	31.6	31.4	0.1
Xanomeline High Dose		Week 2	31.4	31.4	0.0
Xanomeline High Dose		Week 20	31.6	31.4	0.1
Xanomeline High Dose		Week 24	31.4	31.4	0.0
Xanomeline High Dose		Week 26	31.6	31.4	0.1
Xanomeline High Dose		Week 4	31.3	31.4	-0.1
Xanomeline High Dose		Week 6	31.1	31.4	-0.3
Xanomeline High Dose		Week 8	31.4	31.4	0.0
Xanomeline High Dose	01-701-1034	Week 12	26.3	26.1	0.2
Xanomeline High Dose		Week 16	26.8	26.1	0.8
Xanomeline High Dose		Week 2	26.1	26.1	0.0
Xanomeline High Dose		Week 20	27.0	26.1	0.9
Xanomeline High Dose		Week 24	27.2	26.1	1.1
Xanomeline High Dose		Week 26	26.6	26.1	0.6
Xanomeline High Dose		Week 4	26.6	26.1	0.6
Xanomeline High Dose		Week 6	26.6	26.1	0.6
Xanomeline High Dose		Week 8	26.3	26.1	0.2
Placebo	01-701-1047	Week 2	30.6	30.4	0.2
Xanomeline Low Dose	01-701-1097	Week 12	28.0	27.3	0.6
Xanomeline Low Dose		Week 16	27.8	27.3	0.5
Xanomeline Low Dose		Week 2	27.8	27.3	0.5
Xanomeline Low Dose		Week 20	28.0	27.3	0.6
Xanomeline Low Dose		Week 24	28.1	27.3	0.8
Xanomeline Low Dose		Week 26	27.5	27.3	0.2
Xanomeline Low Dose		Week 4	27.8	27.3	0.5
Xanomeline Low Dose		Week 6	27.8	27.3	0.5
Xanomeline Low Dose		Week 8	27.5	27.3	0.2
Xanomeline Low Dose	01-701-1115	Week 2	23.9	23.9	0.0
Xanomeline Low Dose		Week 4	23.8	23.9	-0.1
Xanomeline Low Dose		Week 6	23.8	23.9	-0.1
Xanomeline Low Dose		Week 8	23.8	23.9	-0.1
Placebo	01-701-1118	Week 12	22.6	21.9	0.7
Placebo		Week 16	22.5	21.9	0.6
Placebo		Week 2	21.9	21.9	0.0
Placebo		Week 20	22.0	21.9	0.1
Placebo		Week 24	21.9	21.9	0.0
Placebo		Week 26	22.5	21.9	0.6
Placebo		Week 4	21.9	21.9	0.0
Placebo		Week 6	21.9	21.9	0.0
Placebo		Week 8	22.3	21.9	0.4
Placebo	01-701-1130	Week 12	27.3	27.6	-0.3
Placebo		Week 16	27.3	27.6	-0.3
Placebo		Week 2	27.6	27.6	0.0
Placebo		Week 20	27.4	27.6	-0.2
Placebo		Week 24	26.8	27.6	-0.8
Placebo		Week 26	26.9	27.6	-0.6
Placebo		Week 4	27.1	27.6	-0.5
Placebo		Week 6	27.1	27.6	-0.5
Placebo		Week 8	27.7	27.6	0.2
Xanomeline High Dose	01-701-1133	Week 12	28.8	28.2	0.7
Xanomeline High Dose		Week 16	28.5	28.2	0.3
Xanomeline High Dose		Week 2	28.0	28.2	-0.2
Xanomeline High Dose		Week 20	28.2	28.2	0.0
Xanomeline High Dose		Week 24	27.5	28.2	-0.7
Xanomeline High Dose		Week 4	28.2	28.2	0.0
Xanomeline High Dose		Week 6	28.3	28.2	0.2
Xanomeline High Dose		Week 8	28.5	28.2	0.3
Xanomeline High Dose	01-701-1146	Week 2	25.1	24.9	0.2
Xanomeline High Dose		Week 4	25.1	24.9	0.2
Xanomeline High Dose	01-701-1148	Week 12	28.8	28.4	0.4
Xanomeline High Dose		Week 16	28.6	28.4	0.3
Xanomeline High Dose		Week 2	28.5	28.4	0.1
Xanomeline High Dose		Week 20	29.4	28.4	1.0
Xanomeline High Dose		Week 24	29.4	28.4	1.0
Xanomeline High Dose		Week 26	29.5	28.4	1.2
Xanomeline High Dose		Week 4	28.9	28.4	0.6
Xanomeline High Dose		Week 6	28.5	28.4	0.1
Xanomeline High Dose		Week 8	28.8	28.4	0.4
Placebo	01-701-1153	Week 12	23.4	23.8	-0.4
Placebo		Week 16	23.1	23.8	-0.7
Placebo		Week 2	23.4	23.8	-0.4
Placebo		Week 20	23.4	23.8	-0.4
Placebo		Week 24	23.1	23.8	-0.7
Placebo		Week 4	23.2	23.8	-0.6
Placebo		Week 6	23.6	23.8	-0.2
Placebo		Week 8	23.8	23.8	0.0
Xanomeline High Dose	01-701-1180	Week 2	27.8	27.6	0.1
Xanomeline High Dose		Week 4	27.5	27.6	-0.1
Xanomeline Low Dose	01-701-1188	Week 2	32.1	32.0	0.1
Xanomeline Low Dose		Week 4	32.3	32.0	0.3
Xanomeline Low Dose	01-701-1192	Week 12	27.8	27.8	0.0
Xanomeline Low Dose		Week 16	27.8	27.8	0.0
Xanomeline Low Dose		Week 2	28.0	27.8	0.2
Xanomeline Low Dose		Week 20	27.4	27.8	-0.4
Xanomeline Low Dose		Week 24	27.4	27.8	-0.4
Xanomeline Low Dose		Week 26	27.2	27.8	-0.6
Xanomeline Low Dose		Week 4	28.0	27.8	0.2
Xanomeline Low Dose		Week 6	28.4	27.8	0.6
Xanomeline Low Dose		Week 8	27.2	27.8	-0.6
Placebo	01-701-1203	Week 12	26.4	25.9	0.5
Placebo		Week 16	25.9	25.9	0.0
Placebo		Week 2	26.0	25.9	0.2
Placebo		Week 20	25.3	25.9	-0.5
Placebo		Week 24	25.3	25.9	-0.5
Placebo		Week 26	25.0	25.9	-0.9
Placebo		Week 4	25.7	25.9	-0.2
Placebo		Week 6	26.2	25.9	0.4
Placebo		Week 8	25.9	25.9	0.0
Xanomeline Low Dose	01-701-1211	Week 2	17.7	17.7	0.0
Xanomeline Low Dose		Week 4	17.9	17.7	0.2
Xanomeline Low Dose		Week 6	17.7	17.7	0.0
Xanomeline Low Dose		Week 8	16.8	17.7	-0.9
Placebo	01-701-1234	Week 12	23.2	23.4	-0.1
Placebo		Week 16	23.2	23.4	-0.1
Placebo		Week 2	23.4	23.4	0.0
Placebo		Week 20	23.4	23.4	0.0
Placebo		Week 24	23.2	23.4	-0.1
Placebo		Week 26	23.5	23.4	0.1
Placebo		Week 4	23.4	23.4	0.0
Placebo		Week 6	23.4	23.4	0.0
Placebo		Week 8	23.4	23.4	0.0
Xanomeline High Dose	01-701-1239	Week 12	33.2	33.6	-0.4
Xanomeline High Dose		Week 16	33.5	33.6	-0.1
Xanomeline High Dose		Week 2	33.5	33.6	-0.1
Xanomeline High Dose		Week 20	33.7	33.6	0.1
Xanomeline High Dose		Week 24	34.0	33.6	0.4
Xanomeline High Dose		Week 4	33.4	33.6	-0.2
Xanomeline High Dose		Week 6	33.9	33.6	0.2
Xanomeline High Dose		Week 8	33.1	33.6	-0.6
Xanomeline High Dose	01-701-1275	Week 12	25.0	24.5	0.5
Xanomeline High Dose		Week 2	24.5	24.5	0.0
Xanomeline High Dose		Week 4	24.9	24.5	0.3
Xanomeline High Dose		Week 6	25.3	24.5	0.8
Xanomeline High Dose		Week 8	25.2	24.5	0.6
Xanomeline High Dose	01-701-1287	Week 12	23.4	23.4	0.0
Xanomeline High Dose		Week 16	23.1	23.4	-0.4
Xanomeline High Dose		Week 2	23.8	23.4	0.4
Xanomeline High Dose		Week 20	22.9	23.4	-0.6
Xanomeline High Dose		Week 24	23.2	23.4	-0.2
Xanomeline High Dose		Week 26	23.2	23.4	-0.2
Xanomeline High Dose		Week 4	23.8	23.4	0.4
Xanomeline High Dose		Week 6	23.4	23.4	0.0
Xanomeline High Dose		Week 8	23.2	23.4	-0.2
Xanomeline Low Dose	01-701-1294	Week 12	27.7	27.1	0.6
Xanomeline Low Dose		Week 2	27.1	27.1	0.0
Xanomeline Low Dose		Week 4	27.1	27.1	0.0
Xanomeline Low Dose		Week 6	27.3	27.1	0.2
Xanomeline Low Dose		Week 8	27.6	27.1	0.5
Xanomeline High Dose	01-701-1302	Week 12	26.0	26.0	0.0
Xanomeline High Dose		Week 2	25.7	26.0	-0.3
Xanomeline High Dose		Week 4	26.1	26.0	0.1
Xanomeline High Dose		Week 6	25.5	26.0	-0.4
Xanomeline High Dose		Week 8	26.0	26.0	0.0
Xanomeline Low Dose	01-701-1317	Week 12	20.8	21.4	-0.6
Xanomeline Low Dose		Week 16	21.4	21.4	0.0
Xanomeline Low Dose		Week 2	21.4	21.4	0.0
Xanomeline Low Dose		Week 20	21.5	21.4	0.1
Xanomeline Low Dose		Week 24	21.7	21.4	0.3
Xanomeline Low Dose		Week 26	21.8	21.4	0.4
Xanomeline Low Dose		Week 4	21.8	21.4	0.4
Xanomeline Low Dose		Week 6	21.7	21.4	0.3
Xanomeline Low Dose		Week 8	21.7	21.4	0.3
Xanomeline Low Dose	01-701-1324	Week 12	27.2	27.9	-0.7
Xanomeline Low Dose		Week 16	27.2	27.9	-0.7
Xanomeline Low Dose		Week 2	28.4	27.9	0.5
Xanomeline Low Dose		Week 20	27.9	27.9	0.0
Xanomeline Low Dose		Week 24	27.5	27.9	-0.3
Xanomeline Low Dose		Week 26	27.2	27.9	-0.7
Xanomeline Low Dose		Week 4	28.0	27.9	0.2
Xanomeline Low Dose		Week 6	27.7	27.9	-0.2
Xanomeline Low Dose		Week 8	27.7	27.9	-0.2
Xanomeline Low Dose	01-701-1341	Week 2	28.0	28.5	-0.5
Placebo	01-701-1345	Week 12	18.6	18.6	0.0
Placebo		Week 16	18.7	18.6	0.1
Placebo		Week 2	18.6	18.6	0.0
Placebo		Week 20	18.9	18.6	0.3
Placebo		Week 24	18.9	18.6	0.3
Placebo		Week 4	18.6	18.6	0.0
Placebo		Week 6	18.7	18.6	0.1
Placebo		Week 8	18.6	18.6	0.0
Placebo	01-701-1363	Week 12	25.8	24.9	0.9
Placebo		Week 16	25.3	24.9	0.3
Placebo		Week 2	25.1	24.9	0.2
Placebo		Week 20	24.9	24.9	0.0
Placebo		Week 24	25.1	24.9	0.2
Placebo		Week 26	25.1	24.9	0.2
Placebo		Week 4	25.5	24.9	0.5
Placebo		Week 6	25.6	24.9	0.7
Placebo		Week 8	25.3	24.9	0.3
Xanomeline High Dose	01-701-1383	Week 12	31.4	31.6	-0.2
Xanomeline High Dose		Week 16	31.6	31.6	0.0
Xanomeline High Dose		Week 2	32.1	31.6	0.5
Xanomeline High Dose		Week 20	31.4	31.6	-0.2
Xanomeline High Dose		Week 24	30.9	31.6	-0.7
Xanomeline High Dose		Week 26	30.9	31.6	-0.7
Xanomeline High Dose		Week 4	31.8	31.6	0.2
Xanomeline High Dose		Week 6	31.8	31.6	0.2
Xanomeline High Dose		Week 8	31.8	31.6	0.2
Placebo	01-701-1387	Week 2	23.0	22.5	0.5
Placebo	01-701-1392	Week 12	29.2	28.9	0.3
Placebo		Week 16	28.9	28.9	0.0
Placebo		Week 2	28.9	28.9	0.0
Placebo		Week 20	28.9	28.9	0.0
Placebo		Week 24	29.1	28.9	0.2
Placebo		Week 26	28.9	28.9	0.0
Placebo		Week 4	28.7	28.9	-0.2
Placebo		Week 6	29.1	28.9	0.2
Placebo		Week 8	29.1	28.9	0.2
Placebo	01-701-1415	Week 12	25.4	25.0	0.4
Placebo		Week 16	25.5	25.0	0.6
Placebo		Week 2	25.1	25.0	0.1
Placebo		Week 20	24.4	25.0	-0.6
Placebo		Week 24	25.0	25.0	0.0
Placebo		Week 26	24.8	25.0	-0.1
Placebo		Week 4	25.4	25.0	0.4
Placebo		Week 6	25.5	25.0	0.6
Placebo		Week 8	25.5	25.0	0.6
Xanomeline Low Dose	01-701-1429	Week 2	25.7	25.7	0.0
Xanomeline Low Dose		Week 4	25.9	25.7	0.2
Xanomeline Low Dose		Week 6	25.9	25.7	0.2
Placebo	01-701-1440	Week 12	20.4	20.3	0.2
Placebo		Week 16	20.6	20.3	0.4
Placebo		Week 2	19.9	20.3	-0.4
Placebo		Week 20	20.4	20.3	0.2
Placebo		Week 24	20.3	20.3	0.0
Placebo		Week 26	19.9	20.3	-0.4
Placebo		Week 4	19.9	20.3	-0.4
Placebo		Week 6	20.1	20.3	-0.2
Placebo		Week 8	20.1	20.3	-0.2
Xanomeline Low Dose	01-701-1442	Week 12	40.0	40.2	-0.2
Xanomeline Low Dose		Week 16	40.3	40.2	0.2
Xanomeline Low Dose		Week 2	39.7	40.2	-0.5
Xanomeline Low Dose		Week 20	40.3	40.2	0.2
Xanomeline Low Dose		Week 24	40.2	40.2	0.0
Xanomeline Low Dose		Week 26	39.7	40.2	-0.5
Xanomeline Low Dose		Week 4	40.0	40.2	-0.2
Xanomeline Low Dose		Week 6	40.2	40.2	0.0
Xanomeline Low Dose		Week 8	40.2	40.2	0.0
Xanomeline High Dose	01-701-1444	Week 2	35.5	34.6	0.9
Xanomeline High Dose		Week 4	35.0	34.6	0.5
Xanomeline Low Dose	01-702-1082	Week 2	22.7	22.7	0.0
Xanomeline Low Dose		Week 4	22.7	22.7	0.0
Xanomeline Low Dose		Week 6	22.7	22.7	0.0
Xanomeline Low Dose		Week 8	22.5	22.7	-0.2
Placebo	01-703-1042	Week 12	24.2	23.5	0.7
Placebo		Week 16	24.0	23.5	0.4
Placebo		Week 2	23.1	23.5	-0.4
Placebo		Week 20	23.5	23.5	0.0
Placebo		Week 24	23.5	23.5	0.0
Placebo		Week 26	23.5	23.5	0.0
Placebo		Week 4	23.4	23.5	-0.1
Placebo		Week 6	23.2	23.5	-0.3
Placebo		Week 8	23.5	23.5	0.0
Xanomeline High Dose	01-703-1076	Week 12	32.6	32.0	0.7
Xanomeline High Dose		Week 2	32.0	32.0	0.0
Xanomeline High Dose		Week 4	32.1	32.0	0.2
Xanomeline High Dose		Week 6	32.8	32.0	0.8
Xanomeline High Dose		Week 8	32.8	32.0	0.8
Xanomeline Low Dose	01-703-1086	Week 12	24.8	25.0	-0.2
Xanomeline Low Dose		Week 2	25.8	25.0	0.8
Xanomeline Low Dose		Week 4	25.0	25.0	0.0
Xanomeline Low Dose		Week 6	24.9	25.0	-0.1
Xanomeline Low Dose		Week 8	24.9	25.0	-0.1
Placebo	01-703-1096	Week 2	31.5	31.7	-0.2
Placebo		Week 4	32.8	31.7	1.1
Placebo	01-703-1100	Week 12	22.6	21.8	0.8
Placebo		Week 16	22.6	21.8	0.8
Placebo		Week 2	22.1	21.8	0.3
Placebo		Week 20	23.2	21.8	1.5
Placebo		Week 24	22.6	21.8	0.8
Placebo		Week 26	22.3	21.8	0.5
Placebo		Week 4	22.3	21.8	0.5
Placebo		Week 6	22.3	21.8	0.5
Placebo		Week 8	22.3	21.8	0.5
Xanomeline Low Dose	01-703-1119	Week 12	20.5	18.4	2.1
Xanomeline Low Dose		Week 16	20.2	18.4	1.8
Xanomeline Low Dose		Week 2	19.8	18.4	1.4
Xanomeline Low Dose		Week 4	20.2	18.4	1.8
Xanomeline Low Dose		Week 6	20.2	18.4	1.8
Xanomeline Low Dose		Week 8	19.8	18.4	1.4
Xanomeline Low Dose	01-703-1182	Week 2	22.5	22.8	-0.3
Xanomeline Low Dose		Week 4	22.8	22.8	0.0
Xanomeline Low Dose		Week 6	22.8	22.8	0.0
Placebo	01-703-1210	Week 12	22.5	23.8	-1.3
Placebo		Week 16	22.1	23.8	-1.7
Placebo		Week 2	23.4	23.8	-0.4
Placebo		Week 20	22.3	23.8	-1.5
Placebo		Week 24	21.6	23.8	-2.2
Placebo		Week 26	21.6	23.8	-2.2
Placebo		Week 4	23.2	23.8	-0.6
Placebo		Week 6	22.7	23.8	-1.1
Placebo		Week 8	22.5	23.8	-1.3
Xanomeline High Dose	01-703-1258	Week 12	24.6	24.8	-0.2
Xanomeline High Dose		Week 16	25.1	24.8	0.4
Xanomeline High Dose		Week 2	24.6	24.8	-0.2
Xanomeline High Dose		Week 20	24.6	24.8	-0.2
Xanomeline High Dose		Week 24	24.6	24.8	-0.2
Xanomeline High Dose		Week 4	25.7	24.8	0.9
Xanomeline High Dose		Week 6	25.3	24.8	0.6
Xanomeline High Dose		Week 8	25.7	24.8	0.9
Xanomeline High Dose	01-703-1295	Week 12	22.7	22.7	0.0
Xanomeline High Dose		Week 16	21.9	22.7	-0.7
Xanomeline High Dose		Week 2	23.2	22.7	0.5
Xanomeline High Dose		Week 4	23.0	22.7	0.4
Xanomeline High Dose		Week 6	22.9	22.7	0.2
Xanomeline High Dose		Week 8	22.9	22.7	0.2
Placebo	01-703-1299	Week 12	19.2	19.2	0.0
Placebo		Week 16	19.2	19.2	0.0
Placebo		Week 2	19.2	19.2	0.0
Placebo		Week 20	18.6	19.2	-0.6
Placebo		Week 24	18.4	19.2	-0.8
Placebo		Week 26	18.4	19.2	-0.8
Placebo		Week 4	18.8	19.2	-0.4
Placebo		Week 6	18.8	19.2	-0.4
Placebo		Week 8	19.2	19.2	0.0
Xanomeline High Dose	01-703-1335	Week 2	22.3	23.1	-0.8
Xanomeline High Dose		Week 4	22.3	23.1	-0.8
Xanomeline Low Dose	01-703-1379	Week 12	32.4	30.7	1.6
Xanomeline Low Dose		Week 16	30.5	30.7	-0.2
Xanomeline Low Dose		Week 2	31.3	30.7	0.6
Xanomeline Low Dose		Week 20	30.0	30.7	-0.7
Xanomeline Low Dose		Week 24	28.5	30.7	-2.2
Xanomeline Low Dose		Week 26	28.7	30.7	-2.0
Xanomeline Low Dose		Week 4	31.5	30.7	0.7
Xanomeline Low Dose		Week 6	31.6	30.7	0.9
Xanomeline Low Dose		Week 8	31.6	30.7	0.9
Xanomeline High Dose	01-703-1439	Week 12	24.4	24.8	-0.4
Xanomeline High Dose		Week 16	24.8	24.8	0.0
Xanomeline High Dose		Week 2	24.6	24.8	-0.2
Xanomeline High Dose		Week 20	24.8	24.8	0.0
Xanomeline High Dose		Week 24	24.4	24.8	-0.4
Xanomeline High Dose		Week 26	24.8	24.8	0.0
Xanomeline High Dose		Week 4	24.8	24.8	0.0
Xanomeline High Dose		Week 6	24.1	24.8	-0.7
Xanomeline High Dose		Week 8	24.4	24.8	-0.4
Xanomeline High Dose	01-704-1008	Week 2	21.3	21.3	0.0
Xanomeline High Dose		Week 4	21.5	21.3	0.2
Xanomeline Low Dose	01-704-1009	Week 2	20.7	20.8	-0.1
Placebo	01-704-1010	Week 12	25.5	25.6	-0.1
Placebo		Week 16	25.5	25.6	-0.1
Placebo		Week 2	25.5	25.6	-0.1
Placebo		Week 4	25.5	25.6	-0.1
Placebo		Week 6	25.4	25.6	-0.2
Placebo		Week 8	25.5	25.6	-0.1
Xanomeline High Dose	01-704-1017	Week 2	21.8	21.8	0.0
Xanomeline Low Dose	01-704-1025	Week 2	20.2	20.1	0.1
Xanomeline High Dose	01-704-1065	Week 2	24.8	24.8	0.0
Xanomeline High Dose		Week 4	24.7	24.8	-0.1
Xanomeline High Dose		Week 6	24.5	24.8	-0.3
Xanomeline High Dose		Week 8	24.8	24.8	-0.1
Xanomeline High Dose	01-704-1074	Week 2	27.0	27.0	0.0
Xanomeline High Dose		Week 4	26.8	27.0	-0.2
Xanomeline High Dose		Week 6	27.1	27.0	0.2
Xanomeline High Dose	01-704-1093	Week 12	24.1	24.3	-0.1
Xanomeline High Dose		Week 2	24.3	24.3	0.1
Xanomeline High Dose		Week 4	24.3	24.3	0.0
Xanomeline High Dose		Week 6	24.3	24.3	0.0
Xanomeline High Dose		Week 8	24.3	24.3	0.0
Xanomeline Low Dose	01-704-1114	Week 12	28.2	28.1	0.1
Xanomeline Low Dose		Week 16	28.5	28.1	0.4
Xanomeline Low Dose		Week 2	28.0	28.1	-0.1
Xanomeline Low Dose		Week 20	28.4	28.1	0.2
Xanomeline Low Dose		Week 4	28.0	28.1	-0.1
Xanomeline Low Dose		Week 6	28.4	28.1	0.2
Xanomeline Low Dose		Week 8	28.2	28.1	0.1
Xanomeline Low Dose	01-704-1120	Week 2	22.7	23.9	-1.3
Xanomeline Low Dose		Week 4	22.2	23.9	-1.7
Xanomeline Low Dose		Week 6	22.5	23.9	-1.5
Xanomeline Low Dose		Week 8	22.7	23.9	-1.3
Placebo	01-704-1127	Week 12	15.5	15.1	0.4
Placebo		Week 16	15.6	15.1	0.5
Placebo		Week 2	15.6	15.1	0.6
Placebo		Week 20	15.6	15.1	0.6
Placebo		Week 24	15.6	15.1	0.6
Placebo		Week 26	15.8	15.1	0.7
Placebo		Week 4	15.3	15.1	0.2
Placebo		Week 6	15.6	15.1	0.6
Placebo		Week 8	15.6	15.1	0.6
Xanomeline Low Dose	01-704-1135	Week 12	24.3	24.6	-0.3
Xanomeline Low Dose		Week 16	24.3	24.6	-0.3
Xanomeline Low Dose		Week 2	24.6	24.6	0.0
Xanomeline Low Dose		Week 20	23.4	24.6	-1.2
Xanomeline Low Dose		Week 24	23.7	24.6	-0.9
Xanomeline Low Dose		Week 26	23.5	24.6	-1.1
Xanomeline Low Dose		Week 4	24.8	24.6	0.2
Xanomeline Low Dose		Week 6	24.6	24.6	0.0
Xanomeline Low Dose		Week 8	24.4	24.6	-0.2
Placebo	01-704-1164	Week 12	20.3	20.1	0.2
Placebo		Week 16	20.9	20.1	0.7
Placebo		Week 2	19.8	20.1	-0.4
Placebo		Week 20	20.9	20.1	0.7
Placebo		Week 24	20.9	20.1	0.7
Placebo		Week 26	20.5	20.1	0.4
Placebo		Week 4	19.8	20.1	-0.4
Placebo		Week 6	20.5	20.1	0.4
Placebo		Week 8	20.1	20.1	0.0
Xanomeline Low Dose	01-704-1218	Week 12	27.1	26.2	0.9
Xanomeline Low Dose		Week 16	26.2	26.2	0.0
Xanomeline Low Dose		Week 2	26.9	26.2	0.7
Xanomeline Low Dose		Week 20	26.2	26.2	0.0
Xanomeline Low Dose		Week 24	26.7	26.2	0.4
Xanomeline Low Dose		Week 26	26.7	26.2	0.4
Xanomeline Low Dose		Week 4	27.1	26.2	0.9
Xanomeline Low Dose		Week 6	26.0	26.2	-0.2
Xanomeline Low Dose		Week 8	26.7	26.2	0.4
Placebo	01-704-1233	Week 2	21.9	21.3	0.6
Xanomeline High Dose	01-704-1241	Week 2	25.3	25.2	0.1
Xanomeline High Dose		Week 4	26.5	25.2	1.3
Xanomeline High Dose		Week 6	25.2	25.2	0.0
Placebo	01-704-1260	Week 2	19.0	19.0	-0.1
Placebo		Week 4	18.8	19.0	-0.3
Placebo		Week 6	19.0	19.0	-0.1
Placebo		Week 8	18.7	19.0	-0.4
Xanomeline High Dose	01-704-1266	Week 2	29.1	29.2	-0.1
Xanomeline High Dose		Week 4	29.1	29.2	-0.1
Xanomeline High Dose		Week 6	28.9	29.2	-0.3
Xanomeline High Dose		Week 8	29.1	29.2	-0.1
Xanomeline Low Dose	01-704-1323	Week 2	22.8	22.7	0.2
Xanomeline Low Dose		Week 4	22.6	22.7	-0.1
Xanomeline Low Dose	01-704-1325	Week 2	22.2	22.3	-0.1
Xanomeline Low Dose		Week 4	22.3	22.3	0.0
Xanomeline Low Dose		Week 6	22.2	22.3	-0.1
Xanomeline Low Dose		Week 8	22.3	22.3	0.0
Xanomeline High Dose	01-704-1332	Week 2	25.8	26.2	-0.5
Xanomeline High Dose		Week 4	26.2	26.2	0.0
Xanomeline High Dose		Week 6	25.8	26.2	-0.5
Xanomeline High Dose		Week 8	25.9	26.2	-0.3
Placebo	01-704-1351	Week 12	23.8	23.9	-0.1
Placebo		Week 16	24.5	23.9	0.6
Placebo		Week 2	23.9	23.9	0.0
Placebo		Week 20	24.5	23.9	0.6
Placebo		Week 24	24.5	23.9	0.6
Placebo		Week 26	24.4	23.9	0.4
Placebo		Week 4	24.4	23.9	0.4
Placebo		Week 6	24.2	23.9	0.3
Placebo		Week 8	24.1	23.9	0.1
Placebo	01-704-1388	Week 12	18.5	18.8	-0.3
Placebo		Week 16	18.5	18.8	-0.3
Placebo		Week 2	18.9	18.8	0.1
Placebo		Week 20	18.6	18.8	-0.1
Placebo		Week 24	18.8	18.8	0.0
Placebo		Week 4	18.7	18.8	-0.1
Placebo		Week 6	18.6	18.8	-0.1
Placebo		Week 8	18.8	18.8	0.0
Placebo	01-704-1435	Week 2	27.3	27.1	0.2
Placebo		Week 4	27.3	27.1	0.2
Placebo		Week 6	27.1	27.1	0.0
Placebo	01-704-1445	Week 12	22.7	22.8	-0.1
Placebo		Week 16	22.7	22.8	-0.1
Placebo		Week 2	23.0	22.8	0.1
Placebo		Week 20	22.8	22.8	0.0
Placebo		Week 4	23.0	22.8	0.1
Placebo		Week 6	22.7	22.8	-0.1
Placebo		Week 8	22.8	22.8	0.0
Xanomeline Low Dose	01-705-1031	Week 2	29.4	28.9	0.5
Placebo	01-705-1059	Week 12	21.3	20.4	0.9
Placebo		Week 16	21.6	20.4	1.2
Placebo		Week 2	20.6	20.4	0.2
Placebo		Week 4	20.9	20.4	0.5
Placebo		Week 6	20.9	20.4	0.5
Placebo		Week 8	20.9	20.4	0.5
Placebo	01-705-1186	Week 2	19.3	19.7	-0.4
Xanomeline High Dose	01-705-1280	Week 12	26.9	28.0	-1.1
Xanomeline High Dose		Week 16	26.9	28.0	-1.1
Xanomeline High Dose		Week 2	28.0	28.0	0.0
Xanomeline High Dose		Week 20	26.9	28.0	-1.1
Xanomeline High Dose		Week 24	26.5	28.0	-1.5
Xanomeline High Dose		Week 26	26.9	28.0	-1.1
Xanomeline High Dose		Week 4	27.4	28.0	-0.5
Xanomeline High Dose		Week 6	27.6	28.0	-0.4
Xanomeline High Dose		Week 8	27.4	28.0	-0.5
Xanomeline High Dose	01-705-1281	Week 12	31.1	31.4	-0.4
Xanomeline High Dose		Week 2	31.4	31.4	0.0
Xanomeline High Dose		Week 4	31.4	31.4	0.0
Xanomeline High Dose		Week 6	31.2	31.4	-0.2
Xanomeline High Dose		Week 8	31.2	31.4	-0.2
Placebo	01-705-1282	Week 12	30.0	30.4	-0.4
Placebo		Week 16	30.0	30.4	-0.4
Placebo		Week 2	29.7	30.4	-0.8
Placebo		Week 20	28.5	30.4	-1.9
Placebo		Week 24	30.4	30.4	0.0
Placebo		Week 26	30.2	30.4	-0.2
Placebo		Week 4	30.4	30.4	0.0
Placebo		Week 6	30.4	30.4	0.0
Placebo		Week 8	30.2	30.4	-0.2
Xanomeline Low Dose	01-705-1292	Week 12	26.5	26.8	-0.3
Xanomeline Low Dose		Week 16	26.0	26.8	-0.8
Xanomeline Low Dose		Week 2	27.3	26.8	0.5
Xanomeline Low Dose		Week 20	26.3	26.8	-0.5
Xanomeline Low Dose		Week 24	26.3	26.8	-0.5
Xanomeline Low Dose		Week 4	26.8	26.8	0.0
Xanomeline Low Dose		Week 6	26.6	26.8	-0.2
Xanomeline Low Dose		Week 8	26.8	26.8	0.0
Xanomeline High Dose	01-705-1303	Week 2	27.5	27.5	0.0
Xanomeline High Dose	01-705-1310	Week 12	22.5	22.8	-0.2
Xanomeline High Dose		Week 2	23.6	22.8	0.8
Xanomeline High Dose		Week 4	22.8	22.8	0.0
Xanomeline High Dose		Week 6	22.8	22.8	0.0
Xanomeline High Dose		Week 8	22.5	22.8	-0.2
Placebo	01-705-1349	Week 12	26.6	21.2	5.4
Placebo		Week 16	26.6	21.2	5.4
Placebo		Week 2	20.6	21.2	-0.6
Placebo		Week 20	24.2	21.2	3.0
Placebo		Week 24	25.1	21.2	3.9
Placebo		Week 26	20.6	21.2	-0.6
Placebo		Week 4	21.0	21.2	-0.2
Placebo		Week 6	21.0	21.2	-0.2
Placebo		Week 8	20.8	21.2	-0.4
Xanomeline High Dose	01-705-1377	Week 2	20.8	21.0	-0.2
Xanomeline Low Dose	01-705-1393	Week 12	26.4	26.8	-0.4
Xanomeline Low Dose		Week 16	25.1	26.8	-1.7
Xanomeline Low Dose		Week 2	26.8	26.8	0.0
Xanomeline Low Dose		Week 4	26.6	26.8	-0.2
Xanomeline Low Dose		Week 6	26.1	26.8	-0.8
Xanomeline Low Dose		Week 8	26.6	26.8	-0.2
Xanomeline Low Dose	01-705-1431	Week 12	24.2	24.2	0.0
Xanomeline Low Dose		Week 16	24.6	24.2	0.4
Xanomeline Low Dose		Week 2	24.2	24.2	0.0
Xanomeline Low Dose		Week 20	24.4	24.2	0.2
Xanomeline Low Dose		Week 24	24.4	24.2	0.2
Xanomeline Low Dose		Week 26	24.4	24.2	0.2
Xanomeline Low Dose		Week 4	24.2	24.2	0.0
Xanomeline Low Dose		Week 6	24.2	24.2	0.0
Xanomeline Low Dose		Week 8	24.4	24.2	0.2
Placebo	01-706-1041	Week 12	19.3	20.9	-1.6
Placebo		Week 16	19.4	20.9	-1.5
Placebo		Week 2	20.3	20.9	-0.6
Placebo		Week 20	19.4	20.9	-1.5
Placebo		Week 24	19.5	20.9	-1.4
Placebo		Week 4	20.3	20.9	-0.6
Placebo		Week 6	19.0	20.9	-1.9
Placebo		Week 8	19.4	20.9	-1.5
Xanomeline High Dose	01-706-1049	Week 2	20.7	20.6	0.2
Xanomeline High Dose		Week 4	21.0	20.6	0.4
Placebo	01-707-1206	Week 12	24.9	24.6	0.3
Placebo		Week 16	24.3	24.6	-0.3
Placebo		Week 2	24.9	24.6	0.3
Placebo		Week 20	24.3	24.6	-0.3
Placebo		Week 24	24.3	24.6	-0.3
Placebo		Week 4	24.9	24.6	0.3
Placebo		Week 6	24.6	24.6	0.0
Placebo		Week 8	24.6	24.6	0.0
Xanomeline Low Dose	01-708-1032	Week 2	26.3	26.1	0.1
Xanomeline Low Dose	01-708-1084	Week 12	17.8	17.9	-0.2
Xanomeline Low Dose		Week 16	17.8	17.9	-0.2
Xanomeline Low Dose		Week 2	17.4	17.9	-0.5
Xanomeline Low Dose		Week 20	18.1	17.9	0.2
Xanomeline Low Dose		Week 24	18.2	17.9	0.3
Xanomeline Low Dose		Week 26	18.4	17.9	0.5
Xanomeline Low Dose		Week 4	17.6	17.9	-0.3
Xanomeline Low Dose		Week 6	17.8	17.9	-0.2
Xanomeline Low Dose		Week 8	19.0	17.9	1.1
Placebo	01-708-1087	Week 12	28.9	26.9	2.0
Placebo		Week 16	28.7	26.9	1.8
Placebo		Week 20	28.9	26.9	2.0
Placebo		Week 24	28.4	26.9	1.5
Placebo		Week 26	28.5	26.9	1.6
Placebo		Week 4	28.7	26.9	1.8
Placebo		Week 6	28.5	26.9	1.6
Placebo		Week 8	28.7	26.9	1.8
Placebo	01-708-1158	Week 2	28.2	27.8	0.3
Placebo		Week 4	28.2	27.8	0.3
Placebo	01-708-1171	Week 12	21.6	20.8	0.9
Placebo		Week 16	22.0	20.8	1.2
Placebo		Week 2	20.4	20.8	-0.3
Placebo		Week 20	22.3	20.8	1.5
Placebo		Week 24	22.7	20.8	1.9
Placebo		Week 26	22.7	20.8	1.9
Placebo		Week 4	20.8	20.8	0.0
Placebo		Week 6	21.1	20.8	0.3
Placebo		Week 8	21.3	20.8	0.5
Xanomeline High Dose	01-708-1178	Week 12	23.6	23.0	0.6
Xanomeline High Dose		Week 2	23.1	23.0	0.1
Xanomeline High Dose		Week 4	23.1	23.0	0.1
Xanomeline High Dose		Week 6	23.5	23.0	0.4
Xanomeline High Dose		Week 8	23.1	23.0	0.1
Xanomeline Low Dose	01-708-1213	Week 2	15.6	15.3	0.3
Xanomeline High Dose	01-708-1216	Week 2	26.3	25.8	0.5
Xanomeline High Dose		Week 4	26.3	25.8	0.5
Placebo	01-708-1253	Week 12	22.7	22.0	0.7
Placebo		Week 16	22.7	22.0	0.7
Placebo		Week 2	22.4	22.0	0.4
Placebo		Week 20	22.6	22.0	0.5
Placebo		Week 24	22.2	22.0	0.1
Placebo		Week 26	21.6	22.0	-0.4
Placebo		Week 4	22.7	22.0	0.7
Placebo		Week 6	22.7	22.0	0.7
Placebo		Week 8	22.6	22.0	0.5
Xanomeline Low Dose	01-708-1272	Week 2	25.4	24.9	0.5
Xanomeline Low Dose		Week 4	24.8	24.9	-0.2
Xanomeline Low Dose		Week 6	25.1	24.9	0.2
Placebo	01-708-1286	Week 12	34.0	32.8	1.2
Placebo		Week 16	33.8	32.8	1.0
Placebo		Week 2	33.8	32.8	1.0
Placebo		Week 20	33.8	32.8	1.0
Placebo		Week 24	32.6	32.8	-0.2
Placebo		Week 26	31.6	32.8	-1.2
Placebo		Week 4	32.8	32.8	0.0
Placebo		Week 6	34.0	32.8	1.2
Placebo		Week 8	34.0	32.8	1.2
Placebo	01-708-1296	Week 12	27.4	27.9	-0.5
Placebo		Week 16	26.6	27.9	-1.3
Placebo		Week 2	28.2	27.9	0.3
Placebo		Week 20	27.3	27.9	-0.6
Placebo		Week 24	27.3	27.9	-0.6
Placebo		Week 26	27.4	27.9	-0.5
Placebo		Week 4	27.6	27.9	-0.3
Placebo		Week 6	27.7	27.9	-0.2
Placebo		Week 8	27.1	27.9	-0.8
Xanomeline Low Dose	01-708-1297	Week 12	24.5	23.0	1.6
Xanomeline Low Dose		Week 2	23.9	23.0	0.9
Xanomeline Low Dose		Week 4	24.0	23.0	1.1
Xanomeline Low Dose		Week 6	23.9	23.0	0.9
Xanomeline Low Dose		Week 8	24.3	23.0	1.3
Placebo	01-708-1316	Week 12	23.2	23.4	-0.2
Placebo		Week 16	23.4	23.4	0.0
Placebo		Week 2	23.7	23.4	0.4
Placebo		Week 20	23.2	23.4	-0.2
Placebo		Week 24	23.4	23.4	0.0
Placebo		Week 26	23.4	23.4	0.0
Placebo		Week 4	23.4	23.4	0.0
Placebo		Week 6	23.2	23.4	-0.2
Placebo		Week 8	23.2	23.4	-0.2
Xanomeline High Dose	01-708-1336	Week 12	23.1	24.1	-1.0
Xanomeline High Dose		Week 16	23.4	24.1	-0.7
Xanomeline High Dose		Week 2	24.1	24.1	0.0
Xanomeline High Dose		Week 20	23.1	24.1	-1.0
Xanomeline High Dose		Week 24	22.9	24.1	-1.2
Xanomeline High Dose		Week 26	23.1	24.1	-1.0
Xanomeline High Dose		Week 4	23.5	24.1	-0.6
Xanomeline High Dose		Week 6	23.9	24.1	-0.2
Xanomeline High Dose		Week 8	23.7	24.1	-0.4
Placebo	01-708-1342	Week 12	20.4	20.4	0.0
Placebo		Week 16	20.4	20.4	0.0
Placebo		Week 2	19.9	20.4	-0.5
Placebo		Week 20	20.5	20.4	0.2
Placebo		Week 24	20.0	20.4	-0.3
Placebo		Week 26	20.4	20.4	0.0
Placebo		Week 4	20.2	20.4	-0.2
Placebo		Week 6	20.2	20.4	-0.2
Placebo		Week 8	20.0	20.4	-0.3
Xanomeline High Dose	01-708-1347	Week 12	30.1	29.2	0.9
Xanomeline High Dose		Week 2	29.2	29.2	0.0
Xanomeline High Dose		Week 4	29.8	29.2	0.5
Xanomeline High Dose		Week 6	29.9	29.2	0.7
Xanomeline High Dose		Week 8	30.1	29.2	0.9
Xanomeline Low Dose	01-708-1348	Week 12	23.7	23.6	0.2
Xanomeline Low Dose		Week 16	23.6	23.6	0.0
Xanomeline Low Dose		Week 2	23.7	23.6	0.2
Xanomeline Low Dose		Week 20	23.4	23.6	-0.2
Xanomeline Low Dose		Week 24	23.2	23.6	-0.4
Xanomeline Low Dose		Week 26	25.0	23.6	1.4
Xanomeline Low Dose		Week 4	23.7	23.6	0.2
Xanomeline Low Dose		Week 6	24.4	23.6	0.9
Xanomeline Low Dose		Week 8	24.3	23.6	0.7
Xanomeline Low Dose	01-708-1353	Week 2	20.3	20.3	0.0
Xanomeline Low Dose		Week 4	20.9	20.3	0.5
Xanomeline Low Dose		Week 6	20.3	20.3	0.0
Placebo	01-708-1378	Week 12	24.3	24.3	0.0
Placebo		Week 16	24.1	24.3	-0.2
Placebo		Week 2	24.7	24.3	0.5
Placebo		Week 20	23.6	24.3	-0.6
Placebo		Week 4	24.7	24.3	0.5
Placebo		Week 6	24.4	24.3	0.2
Placebo		Week 8	24.3	24.3	0.0
Xanomeline High Dose	01-708-1406	Week 12	22.5	22.1	0.4
Xanomeline High Dose		Week 16	22.5	22.1	0.4
Xanomeline High Dose		Week 2	22.5	22.1	0.4
Xanomeline High Dose		Week 20	23.0	22.1	0.9
Xanomeline High Dose		Week 24	22.9	22.1	0.7
Xanomeline High Dose		Week 26	22.9	22.1	0.7
Xanomeline High Dose		Week 4	22.5	22.1	0.4
Xanomeline High Dose		Week 6	22.7	22.1	0.5
Xanomeline High Dose		Week 8	22.3	22.1	0.2
Xanomeline Low Dose	01-708-1428	Week 2	24.5	23.8	0.7
Xanomeline Low Dose		Week 4	24.5	23.8	0.7
Placebo	01-709-1001	Week 12	25.2	25.2	0.0
Placebo		Week 16	24.7	25.2	-0.5
Placebo		Week 2	25.2	25.2	0.0
Placebo		Week 20	24.6	25.2	-0.6
Placebo		Week 24	24.6	25.2	-0.6
Placebo		Week 26	24.7	25.2	-0.5
Placebo		Week 4	25.1	25.2	-0.2
Placebo		Week 6	25.5	25.2	0.3
Placebo		Week 8	25.1	25.2	-0.2
Xanomeline Low Dose	01-709-1007	Week 2	23.9	23.8	0.2
Xanomeline Low Dose	01-709-1020	Week 12	25.1	26.0	-0.9
Xanomeline Low Dose		Week 16	24.9	26.0	-1.1
Xanomeline Low Dose		Week 2	26.2	26.0	0.2
Xanomeline Low Dose		Week 20	25.6	26.0	-0.3
Xanomeline Low Dose		Week 24	25.5	26.0	-0.4
Xanomeline Low Dose		Week 26	24.9	26.0	-1.1
Xanomeline Low Dose		Week 4	26.2	26.0	0.2
Xanomeline Low Dose		Week 6	25.8	26.0	-0.2
Xanomeline Low Dose		Week 8	25.1	26.0	-0.9
Xanomeline High Dose	01-709-1029	Week 12	23.4	23.1	0.3
Xanomeline High Dose		Week 16	23.4	23.1	0.3
Xanomeline High Dose		Week 2	23.6	23.1	0.5
Xanomeline High Dose		Week 20	22.4	23.1	-0.8
Xanomeline High Dose		Week 24	22.5	23.1	-0.6
Xanomeline High Dose		Week 26	22.2	23.1	-0.9
Xanomeline High Dose		Week 4	23.7	23.1	0.6
Xanomeline High Dose		Week 6	23.8	23.1	0.7
Xanomeline High Dose		Week 8	23.6	23.1	0.5
Xanomeline Low Dose	01-709-1081	Week 12	23.8	23.5	0.3
Xanomeline Low Dose		Week 2	23.5	23.5	0.0
Xanomeline Low Dose		Week 4	23.4	23.5	-0.1
Xanomeline Low Dose		Week 6	23.4	23.5	-0.1
Xanomeline Low Dose		Week 8	24.2	23.5	0.7
Placebo	01-709-1088	Week 12	24.3	24.8	-0.4
Placebo		Week 16	24.0	24.8	-0.7
Placebo		Week 2	24.6	24.8	-0.1
Placebo		Week 20	23.8	24.8	-1.0
Placebo		Week 24	23.8	24.8	-1.0
Placebo		Week 26	23.3	24.8	-1.4
Placebo		Week 4	24.8	24.8	0.0
Placebo		Week 6	24.8	24.8	0.0
Placebo		Week 8	24.6	24.8	-0.1
Xanomeline High Dose	01-709-1099	Week 12	19.6	19.6	0.0
Xanomeline High Dose		Week 16	19.6	19.6	0.0
Xanomeline High Dose		Week 2	19.6	19.6	0.0
Xanomeline High Dose		Week 20	19.3	19.6	-0.3
Xanomeline High Dose		Week 24	19.6	19.6	0.0
Xanomeline High Dose		Week 26	19.1	19.6	-0.5
Xanomeline High Dose		Week 4	20.1	19.6	0.5
Xanomeline High Dose		Week 6	20.5	19.6	0.8
Xanomeline High Dose		Week 8	19.8	19.6	0.2
Xanomeline Low Dose	01-709-1102	Week 2	32.1	32.1	0.0
Xanomeline Low Dose		Week 4	31.6	32.1	-0.5
Xanomeline Low Dose		Week 6	31.3	32.1	-0.8
Xanomeline Low Dose		Week 8	30.8	32.1	-1.3
Xanomeline High Dose	01-709-1168	Week 2	28.3	27.7	0.6
Xanomeline High Dose		Week 4	28.1	27.7	0.4
Xanomeline High Dose		Week 6	28.3	27.7	0.6
Xanomeline Low Dose	01-709-1217	Week 12	23.1	23.1	0.0
Xanomeline Low Dose		Week 2	23.5	23.1	0.3
Xanomeline Low Dose		Week 4	23.5	23.1	0.3
Xanomeline Low Dose		Week 6	23.3	23.1	0.2
Xanomeline Low Dose		Week 8	23.3	23.1	0.2
Xanomeline High Dose	01-709-1238	Week 2	27.8	28.5	-0.7
Xanomeline High Dose		Week 4	28.5	28.5	0.0
Xanomeline High Dose		Week 6	28.0	28.5	-0.5
Xanomeline High Dose		Week 8	26.9	28.5	-1.6
Placebo	01-709-1259	Week 12	21.9	21.9	0.0
Placebo		Week 16	22.4	21.9	0.5
Placebo		Week 2	21.9	21.9	0.0
Placebo		Week 20	22.8	21.9	0.9
Placebo		Week 4	22.4	21.9	0.5
Placebo		Week 6	22.5	21.9	0.6
Placebo		Week 8	21.9	21.9	0.0
Xanomeline Low Dose	01-709-1285	Week 2	23.2	23.1	0.2
Xanomeline Low Dose		Week 4	23.7	23.1	0.6
Xanomeline Low Dose		Week 6	23.7	23.1	0.6
Xanomeline Low Dose		Week 8	23.7	23.1	0.6
Placebo	01-709-1301	Week 12	22.5	23.6	-1.1
Placebo		Week 16	22.3	23.6	-1.3
Placebo		Week 2	23.2	23.6	-0.4
Placebo		Week 20	23.3	23.6	-0.3
Placebo		Week 24	23.3	23.6	-0.3
Placebo		Week 26	23.4	23.6	-0.2
Placebo		Week 4	23.8	23.6	0.2
Placebo		Week 6	23.8	23.6	0.2
Placebo		Week 8	23.8	23.6	0.2
Placebo	01-709-1306	Week 12	18.7	18.5	0.2
Placebo		Week 16	18.3	18.5	-0.2
Placebo		Week 2	18.7	18.5	0.2
Placebo		Week 4	18.7	18.5	0.2
Placebo		Week 6	18.7	18.5	0.2
Placebo		Week 8	18.7	18.5	0.2
Xanomeline High Dose	01-709-1309	Week 12	24.7	24.8	-0.1
Xanomeline High Dose		Week 16	24.8	24.8	0.0
Xanomeline High Dose		Week 2	25.0	24.8	0.1
Xanomeline High Dose		Week 20	25.0	24.8	0.1
Xanomeline High Dose		Week 24	24.4	24.8	-0.4
Xanomeline High Dose		Week 26	24.7	24.8	-0.1
Xanomeline High Dose		Week 4	25.1	24.8	0.3
Xanomeline High Dose		Week 6	25.0	24.8	0.1
Xanomeline High Dose		Week 8	25.1	24.8	0.3
Placebo	01-709-1312	Week 12	21.3	20.9	0.4
Placebo		Week 16	21.3	20.9	0.4
Placebo		Week 2	21.1	20.9	0.2
Placebo		Week 20	21.4	20.9	0.5
Placebo		Week 24	20.9	20.9	0.0
Placebo		Week 26	20.5	20.9	-0.4
Placebo		Week 4	21.4	20.9	0.5
Placebo		Week 6	22.1	20.9	1.2
Placebo		Week 8	22.1	20.9	1.2
Xanomeline Low Dose	01-709-1326	Week 12	28.2	28.8	-0.5
Xanomeline Low Dose		Week 16	28.2	28.8	-0.5
Xanomeline Low Dose		Week 2	28.8	28.8	0.0
Xanomeline Low Dose		Week 20	27.9	28.8	-0.9
Xanomeline Low Dose		Week 24	27.0	28.8	-1.7
Xanomeline Low Dose		Week 26	27.0	28.8	-1.7
Xanomeline Low Dose		Week 4	28.6	28.8	-0.2
Xanomeline Low Dose		Week 6	28.4	28.8	-0.3
Xanomeline Low Dose		Week 8	28.1	28.8	-0.7
Placebo	01-709-1339	Week 12	25.5	25.4	0.1
Placebo		Week 16	25.7	25.4	0.3
Placebo		Week 2	25.3	25.4	-0.1
Placebo		Week 20	25.8	25.4	0.4
Placebo		Week 24	25.8	25.4	0.4
Placebo		Week 26	25.3	25.4	-0.1
Placebo		Week 4	25.3	25.4	-0.1
Placebo		Week 6	25.5	25.4	0.1
Xanomeline Low Dose	01-710-1002	Week 2	25.8	25.8	0.0
Xanomeline High Dose	01-710-1006	Week 12	24.4	25.1	-0.6
Xanomeline High Dose		Week 16	24.3	25.1	-0.8
Xanomeline High Dose		Week 2	24.7	25.1	-0.3
Xanomeline High Dose		Week 20	24.1	25.1	-0.9
Xanomeline High Dose		Week 24	24.0	25.1	-1.1
Xanomeline High Dose		Week 4	24.6	25.1	-0.5
Xanomeline High Dose		Week 6	26.5	25.1	1.4
Xanomeline High Dose		Week 8	24.6	25.1	-0.5
Xanomeline High Dose	01-710-1021	Week 2	20.9	21.3	-0.3
Xanomeline High Dose		Week 4	20.9	21.3	-0.3
Placebo	01-710-1027	Week 12	24.1	24.4	-0.3
Placebo		Week 16	24.1	24.4	-0.3
Placebo		Week 2	24.0	24.4	-0.5
Placebo		Week 20	24.0	24.4	-0.5
Placebo		Week 24	24.1	24.4	-0.3
Placebo		Week 26	23.6	24.4	-0.8
Placebo		Week 4	23.8	24.4	-0.6
Placebo		Week 6	24.3	24.4	-0.2
Placebo		Week 8	24.3	24.4	-0.2
Xanomeline Low Dose	01-710-1045	Week 2	22.0	22.0	0.0
Xanomeline Low Dose		Week 4	20.6	22.0	-1.4
Xanomeline Low Dose		Week 6	21.1	22.0	-0.9
Xanomeline Low Dose		Week 8	21.6	22.0	-0.3
Xanomeline Low Dose	01-710-1053	Week 2	20.7	20.9	-0.2
Xanomeline Low Dose		Week 4	20.5	20.9	-0.4
Xanomeline Low Dose		Week 6	20.9	20.9	0.0
Placebo	01-710-1060	Week 12	20.5	21.0	-0.5
Placebo		Week 16	20.6	21.0	-0.4
Placebo		Week 2	21.2	21.0	0.1
Placebo		Week 20	20.3	21.0	-0.7
Placebo		Week 24	20.6	21.0	-0.4
Placebo		Week 26	20.6	21.0	-0.4
Placebo		Week 4	21.3	21.0	0.3
Placebo		Week 6	20.2	21.0	-0.8
Placebo		Week 8	20.2	21.0	-0.8
Xanomeline High Dose	01-710-1070	Week 12	21.8	21.8	0.0
Xanomeline High Dose		Week 16	21.6	21.8	-0.2
Xanomeline High Dose		Week 2	22.8	21.8	1.0
Xanomeline High Dose		Week 4	22.0	21.8	0.2
Xanomeline High Dose		Week 6	22.6	21.8	0.8
Xanomeline High Dose		Week 8	22.2	21.8	0.4
Placebo	01-710-1077	Week 12	19.9	18.5	1.4
Placebo		Week 16	19.4	18.5	0.9
Placebo		Week 2	19.6	18.5	1.0
Placebo		Week 20	18.7	18.5	0.2
Placebo		Week 24	18.5	18.5	0.0
Placebo		Week 26	18.9	18.5	0.3
Placebo		Week 4	19.7	18.5	1.2
Placebo		Week 6	19.2	18.5	0.7
Placebo		Week 8	19.9	18.5	1.4
Placebo	01-710-1078	Week 12	18.4	18.0	0.4
Placebo		Week 16	17.8	18.0	-0.2
Placebo		Week 2	18.0	18.0	0.0
Placebo		Week 20	17.6	18.0	-0.4
Placebo		Week 24	17.8	18.0	-0.2
Placebo		Week 26	17.6	18.0	-0.4
Placebo		Week 4	18.0	18.0	0.0
Placebo		Week 6	18.0	18.0	0.0
Placebo		Week 8	18.4	18.0	0.4
Xanomeline High Dose	01-710-1137	Week 2	23.6	24.0	-0.3
Xanomeline High Dose		Week 4	23.3	24.0	-0.7
Xanomeline High Dose		Week 6	23.5	24.0	-0.5
Xanomeline High Dose	01-710-1142	Week 2	24.8	24.8	0.0
Xanomeline Low Dose	01-710-1154	Week 2	32.1	32.2	-0.2
Xanomeline Low Dose		Week 4	32.4	32.2	0.2
Xanomeline Low Dose	01-710-1166	Week 12	21.9	22.1	-0.2
Xanomeline Low Dose		Week 2	22.1	22.1	0.0
Xanomeline Low Dose		Week 4	22.3	22.1	0.2
Xanomeline Low Dose		Week 6	21.9	22.1	-0.2
Xanomeline Low Dose		Week 8	21.9	22.1	-0.2
Placebo	01-710-1183	Week 12	22.0	21.2	0.8
Placebo		Week 16	21.4	21.2	0.2
Placebo		Week 2	21.2	21.2	0.0
Placebo		Week 20	21.2	21.2	0.0
Placebo		Week 24	20.8	21.2	-0.4
Placebo		Week 26	21.0	21.2	-0.2
Placebo		Week 4	21.2	21.2	0.0
Placebo		Week 6	21.2	21.2	0.0
Placebo		Week 8	21.2	21.2	0.0
Xanomeline High Dose	01-710-1187	Week 12	21.2	20.8	0.4
Xanomeline High Dose		Week 16	20.8	20.8	0.0
Xanomeline High Dose		Week 2	20.8	20.8	0.0
Xanomeline High Dose		Week 20	21.2	20.8	0.4
Xanomeline High Dose		Week 24	21.5	20.8	0.8
Xanomeline High Dose		Week 26	20.8	20.8	0.0
Xanomeline High Dose		Week 4	20.6	20.8	-0.2
Xanomeline High Dose		Week 6	20.4	20.8	-0.4
Xanomeline High Dose		Week 8	20.8	20.8	0.0
Xanomeline Low Dose	01-710-1235	Week 12	33.0	33.0	0.0
Xanomeline Low Dose		Week 16	32.3	33.0	-0.8
Xanomeline Low Dose		Week 2	33.2	33.0	0.2
Xanomeline Low Dose		Week 20	32.4	33.0	-0.6
Xanomeline Low Dose		Week 24	31.8	33.0	-1.3
Xanomeline Low Dose		Week 26	31.3	33.0	-1.7
Xanomeline Low Dose		Week 4	33.4	33.0	0.3
Xanomeline Low Dose		Week 6	32.7	33.0	-0.3
Xanomeline Low Dose		Week 8	32.7	33.0	-0.3
Xanomeline High Dose	01-710-1249	Week 12	26.3	25.4	0.9
Xanomeline High Dose		Week 16	25.8	25.4	0.4
Xanomeline High Dose		Week 2	26.0	25.4	0.6
Xanomeline High Dose		Week 20	25.7	25.4	0.3
Xanomeline High Dose		Week 24	26.1	25.4	0.7
Xanomeline High Dose		Week 26	25.8	25.4	0.4
Xanomeline High Dose		Week 4	26.0	25.4	0.6
Xanomeline High Dose		Week 6	26.1	25.4	0.7
Xanomeline High Dose		Week 8	26.1	25.4	0.7
Placebo	01-710-1264	Week 12	28.7	29.1	-0.3
Placebo		Week 16	29.1	29.1	0.0
Placebo		Week 2	28.7	29.1	-0.3
Placebo		Week 4	28.9	29.1	-0.2
Placebo		Week 6	28.4	29.1	-0.6
Placebo		Week 8	29.1	29.1	0.0
Xanomeline Low Dose	01-710-1270	Week 2	26.5	25.7	0.8
Placebo	01-710-1271	Week 2	21.2	21.2	0.0
Placebo		Week 4	22.0	21.2	0.8
Placebo		Week 6	22.2	21.2	1.0
Xanomeline High Dose	01-710-1278	Week 2	22.4	22.7	-0.3
Xanomeline High Dose		Week 4	22.7	22.7	0.0
Xanomeline High Dose		Week 6	22.7	22.7	0.0
Xanomeline High Dose		Week 8	22.4	22.7	-0.3
Xanomeline Low Dose	01-710-1300	Week 2	20.5	20.1	0.4
Xanomeline Low Dose		Week 4	20.7	20.1	0.6
Xanomeline Low Dose		Week 6	20.9	20.1	0.8
Xanomeline Low Dose		Week 8	20.3	20.1	0.2
Placebo	01-710-1314	Week 2	22.9	22.7	0.2
Placebo		Week 4	22.4	22.7	-0.2
Placebo	01-710-1315	Week 12	24.4	24.2	0.2
Placebo		Week 16	24.2	24.2	0.0
Placebo		Week 2	24.4	24.2	0.2
Placebo		Week 4	24.4	24.2	0.2
Placebo		Week 6	24.2	24.2	0.0
Placebo		Week 8	24.0	24.2	-0.2
Xanomeline High Dose	01-710-1354	Week 12	26.7	26.7	0.0
Xanomeline High Dose		Week 16	26.2	26.7	-0.5
Xanomeline High Dose		Week 2	27.0	26.7	0.3
Xanomeline High Dose		Week 20	26.3	26.7	-0.4
Xanomeline High Dose		Week 24	26.3	26.7	-0.4
Xanomeline High Dose		Week 26	26.4	26.7	-0.3
Xanomeline High Dose		Week 4	27.0	26.7	0.3
Xanomeline High Dose		Week 6	26.6	26.7	-0.1
Xanomeline High Dose		Week 8	27.1	26.7	0.4
Xanomeline Low Dose	01-710-1358	Week 12	31.2	31.1	0.2
Xanomeline Low Dose		Week 16	31.1	31.1	0.0
Xanomeline Low Dose		Week 2	31.2	31.1	0.2
Xanomeline Low Dose		Week 20	30.9	31.1	-0.2
Xanomeline Low Dose		Week 4	31.4	31.1	0.3
Xanomeline Low Dose		Week 6	31.1	31.1	0.0
Xanomeline Low Dose		Week 8	31.1	31.1	0.0
Placebo	01-710-1368	Week 12	15.7	15.7	0.0
Placebo		Week 16	15.3	15.7	-0.4
Placebo		Week 2	15.3	15.7	-0.4
Placebo		Week 20	15.5	15.7	-0.2
Placebo		Week 24	15.7	15.7	0.0
Placebo		Week 26	15.9	15.7	0.2
Placebo		Week 4	15.9	15.7	0.2
Placebo		Week 6	15.9	15.7	0.2
Placebo		Week 8	15.9	15.7	0.2
Xanomeline Low Dose	01-710-1385	Week 12	25.2	25.2	0.0
Xanomeline Low Dose		Week 16	25.4	25.2	0.1
Xanomeline Low Dose		Week 2	25.2	25.2	0.0
Xanomeline Low Dose		Week 4	24.8	25.2	-0.4
Xanomeline Low Dose		Week 6	25.1	25.2	-0.1
Xanomeline Low Dose		Week 8	25.1	25.2	-0.1
Xanomeline High Dose	01-710-1408	Week 12	33.3	34.2	-0.9
Xanomeline High Dose		Week 16	33.3	34.2	-0.9
Xanomeline High Dose		Week 2	33.7	34.2	-0.4
Xanomeline High Dose		Week 20	33.4	34.2	-0.7
Xanomeline High Dose		Week 24	33.4	34.2	-0.7
Xanomeline High Dose		Week 26	33.3	34.2	-0.9
Xanomeline High Dose		Week 4	33.4	34.2	-0.7
Xanomeline High Dose		Week 6	33.1	34.2	-1.0
Xanomeline High Dose		Week 8	32.7	34.2	-1.4
Xanomeline High Dose	01-711-1012	Week 2	28.3	28.0	0.4
Placebo	01-711-1036	Week 12	23.0	23.4	-0.4
Placebo		Week 16	23.5	23.4	0.1
Placebo		Week 2	23.1	23.4	-0.3
Placebo		Week 20	23.2	23.4	-0.2
Placebo		Week 24	23.2	23.4	-0.2
Placebo		Week 26	23.0	23.4	-0.4
Placebo		Week 4	23.0	23.4	-0.4
Placebo		Week 6	22.6	23.4	-0.8
Placebo		Week 8	22.9	23.4	-0.5
Xanomeline Low Dose	01-711-1143	Week 2	24.9	24.3	0.6
Xanomeline Low Dose		Week 4	25.0	24.3	0.7
Xanomeline Low Dose		Week 6	24.4	24.3	0.1
Xanomeline Low Dose		Week 8	24.3	24.3	0.0
Xanomeline Low Dose	01-713-1043	Week 12	18.8	18.8	0.0
Xanomeline Low Dose		Week 16	18.8	18.8	0.0
Xanomeline Low Dose		Week 2	19.0	18.8	0.2
Xanomeline Low Dose		Week 20	19.0	18.8	0.2
Xanomeline Low Dose		Week 24	19.1	18.8	0.3
Xanomeline Low Dose		Week 26	20.1	18.8	1.3
Xanomeline Low Dose		Week 4	18.8	18.8	0.0
Xanomeline Low Dose		Week 6	18.8	18.8	0.0
Xanomeline Low Dose		Week 8	19.1	18.8	0.3
Xanomeline Low Dose	01-713-1073	Week 12	20.3	20.3	0.0
Xanomeline Low Dose		Week 16	21.3	20.3	1.0
Xanomeline Low Dose		Week 2	20.3	20.3	0.0
Xanomeline Low Dose		Week 20	20.3	20.3	0.0
Xanomeline Low Dose		Week 24	20.3	20.3	0.0
Xanomeline Low Dose		Week 26	20.3	20.3	0.0
Xanomeline Low Dose		Week 4	20.3	20.3	0.0
Xanomeline Low Dose		Week 6	20.3	20.3	0.0
Xanomeline Low Dose		Week 8	20.3	20.3	0.0
Xanomeline High Dose	01-713-1106	Week 12	19.9	19.5	0.3
Xanomeline High Dose		Week 16	20.0	19.5	0.5
Xanomeline High Dose		Week 2	19.7	19.5	0.2
Xanomeline High Dose		Week 20	19.7	19.5	0.2
Xanomeline High Dose		Week 24	19.4	19.5	-0.2
Xanomeline High Dose		Week 26	19.9	19.5	0.3
Xanomeline High Dose		Week 4	19.7	19.5	0.2
Xanomeline High Dose		Week 6	19.5	19.5	0.0
Xanomeline High Dose		Week 8	20.2	19.5	0.7
Xanomeline High Dose	01-713-1141	Week 2	23.5	23.5	0.0
Xanomeline High Dose		Week 4	23.4	23.5	-0.2
Placebo	01-713-1179	Week 12	19.6	20.3	-0.7
Placebo		Week 16	19.5	20.3	-0.8
Placebo		Week 2	20.8	20.3	0.5
Placebo		Week 20	18.6	20.3	-1.7
Placebo		Week 24	18.6	20.3	-1.7
Placebo		Week 26	18.5	20.3	-1.8
Placebo		Week 4	20.8	20.3	0.5
Placebo		Week 6	19.3	20.3	-1.0
Placebo		Week 8	19.8	20.3	-0.5
Xanomeline High Dose	01-713-1209	Week 12	19.1	19.1	0.0
Xanomeline High Dose		Week 16	19.1	19.1	0.0
Xanomeline High Dose		Week 2	19.1	19.1	0.0
Xanomeline High Dose		Week 20	20.0	19.1	0.8
Xanomeline High Dose		Week 24	20.0	19.1	0.8
Xanomeline High Dose		Week 26	20.3	19.1	1.2
Xanomeline High Dose		Week 4	19.1	19.1	0.0
Xanomeline High Dose		Week 6	19.1	19.1	0.0
Xanomeline High Dose		Week 8	19.1	19.1	0.0
Placebo	01-713-1256	Week 12	24.1	23.7	0.4
Placebo		Week 16	23.4	23.7	-0.3
Placebo		Week 2	23.4	23.7	-0.3
Placebo		Week 20	24.3	23.7	0.6
Placebo		Week 24	23.4	23.7	-0.3
Placebo		Week 26	23.7	23.7	0.0
Placebo		Week 4	23.4	23.7	-0.3
Placebo		Week 6	23.4	23.7	-0.3
Placebo		Week 8	24.0	23.7	0.3
Placebo	01-713-1269	Week 12	23.7	21.9	1.8
Placebo		Week 16	23.7	21.9	1.8
Placebo		Week 2	21.9	21.9	0.0
Placebo		Week 20	23.5	21.9	1.6
Placebo		Week 24	23.7	21.9	1.8
Placebo		Week 26	23.0	21.9	1.1
Placebo		Week 4	21.9	21.9	0.0
Placebo		Week 6	23.0	21.9	1.1
Placebo		Week 8	23.0	21.9	1.1
Xanomeline Low Dose	01-713-1448	Week 12	25.5	25.5	0.0
Xanomeline Low Dose		Week 2	25.5	25.5	0.0
Xanomeline Low Dose		Week 4	25.5	25.5	0.0
Xanomeline Low Dose		Week 6	25.5	25.5	0.0
Xanomeline Low Dose		Week 8	25.5	25.5	0.0
Placebo	01-714-1035	Week 12	25.3	24.7	0.6
Placebo		Week 16	24.9	24.7	0.2
Placebo		Week 2	24.7	24.7	0.0
Placebo		Week 20	24.7	24.7	0.0
Placebo		Week 24	24.9	24.7	0.2
Placebo		Week 26	24.9	24.7	0.2
Placebo		Week 4	24.7	24.7	0.0
Placebo		Week 6	25.0	24.7	0.3
Placebo		Week 8	25.3	24.7	0.6
Xanomeline Low Dose	01-714-1068	Week 2	22.7	23.0	-0.4
Xanomeline Low Dose		Week 4	22.5	23.0	-0.6
Xanomeline Low Dose		Week 6	23.6	23.0	0.6
Xanomeline Low Dose		Week 8	23.4	23.0	0.4
Xanomeline Low Dose	01-714-1195	Week 12	28.4	28.7	-0.3
Xanomeline Low Dose		Week 16	29.1	28.7	0.4
Xanomeline Low Dose		Week 2	28.6	28.7	-0.2
Xanomeline Low Dose		Week 20	28.8	28.7	0.1
Xanomeline Low Dose		Week 24	28.7	28.7	0.0
Xanomeline Low Dose		Week 26	28.6	28.7	-0.2
Xanomeline Low Dose		Week 4	28.9	28.7	0.2
Xanomeline Low Dose		Week 6	28.2	28.7	-0.5
Xanomeline Low Dose		Week 8	28.3	28.7	-0.5
Xanomeline High Dose	01-714-1288	Week 12	19.1	18.7	0.4
Xanomeline High Dose		Week 16	19.2	18.7	0.5
Xanomeline High Dose		Week 2	19.1	18.7	0.4
Xanomeline High Dose		Week 20	19.2	18.7	0.5
Xanomeline High Dose		Week 24	18.9	18.7	0.2
Xanomeline High Dose		Week 26	18.9	18.7	0.2
Xanomeline High Dose		Week 4	19.1	18.7	0.3
Xanomeline High Dose		Week 6	19.1	18.7	0.3
Xanomeline High Dose		Week 8	19.1	18.7	0.3
Placebo	01-714-1375	Week 12	25.9	25.7	0.2
Placebo		Week 16	25.7	25.7	0.0
Placebo		Week 2	25.2	25.7	-0.4
Placebo		Week 20	25.8	25.7	0.1
Placebo		Week 24	26.1	25.7	0.4
Placebo		Week 26	26.1	25.7	0.4
Placebo		Week 4	25.9	25.7	0.2
Placebo		Week 6	25.2	25.7	-0.4
Placebo		Week 8	25.4	25.7	-0.2
Xanomeline Low Dose	01-715-1085	Week 12	21.3	21.8	-0.5
Xanomeline Low Dose		Week 16	21.6	21.8	-0.2
Xanomeline Low Dose		Week 2	21.3	21.8	-0.5
Xanomeline Low Dose		Week 20	21.8	21.8	0.0
Xanomeline Low Dose		Week 24	21.5	21.8	-0.3
Xanomeline Low Dose		Week 26	22.1	21.8	0.3
Xanomeline Low Dose		Week 4	20.8	21.8	-1.0
Xanomeline Low Dose		Week 6	21.5	21.8	-0.3
Xanomeline Low Dose		Week 8	21.5	21.8	-0.3
Xanomeline Low Dose	01-715-1107	Week 2	23.3	23.3	0.0
Xanomeline Low Dose		Week 4	22.8	23.3	-0.5
Xanomeline Low Dose		Week 6	22.8	23.3	-0.5
Xanomeline Low Dose		Week 8	24.2	23.3	0.9
Placebo	01-715-1155	Week 2	23.3	23.3	0.0
Placebo		Week 4	23.3	23.3	0.0
Placebo	01-715-1207	Week 12	21.5	21.3	0.2
Placebo		Week 16	21.5	21.3	0.2
Placebo		Week 2	21.1	21.3	-0.2
Placebo		Week 20	22.1	21.3	0.8
Placebo		Week 24	21.5	21.3	0.2
Placebo		Week 4	21.1	21.3	-0.2
Placebo		Week 6	21.1	21.3	-0.2
Placebo		Week 8	21.7	21.3	0.4
Xanomeline High Dose	01-715-1319	Week 2	24.9	25.4	-0.5
Xanomeline High Dose	01-715-1321	Week 2	22.8	22.7	0.2
Xanomeline High Dose		Week 4	22.7	22.7	0.0
Xanomeline High Dose		Week 6	22.5	22.7	-0.2
Xanomeline High Dose		Week 8	22.7	22.7	0.0
Placebo	01-715-1397	Week 12	30.9	28.9	2.0
Placebo		Week 16	30.7	28.9	1.8
Placebo		Week 2	29.3	28.9	0.4
Placebo		Week 20	30.1	28.9	1.2
Placebo		Week 24	29.7	28.9	0.8
Placebo		Week 4	29.9	28.9	1.0
Placebo		Week 6	30.5	28.9	1.6
Placebo		Week 8	30.9	28.9	2.0
Placebo	01-716-1024	Week 12	23.1	22.7	0.4
Placebo		Week 16	23.1	22.7	0.4
Placebo		Week 2	22.9	22.7	0.2
Placebo		Week 20	22.7	22.7	0.0
Placebo		Week 24	23.1	22.7	0.4
Placebo		Week 26	23.5	22.7	0.8
Placebo		Week 4	22.7	22.7	0.0
Placebo		Week 6	22.7	22.7	0.0
Placebo		Week 8	22.9	22.7	0.2
Placebo	01-716-1026	Week 12	32.1	33.3	-1.1
Placebo		Week 16	32.9	33.3	-0.4
Placebo		Week 2	33.6	33.3	0.4
Placebo		Week 20	33.5	33.3	0.3
Placebo		Week 24	33.4	33.3	0.2
Placebo		Week 26	33.4	33.3	0.2
Placebo		Week 4	33.4	33.3	0.2
Placebo		Week 6	34.0	33.3	0.8
Placebo		Week 8	33.4	33.3	0.2
Placebo	01-716-1044	Week 12	28.3	28.9	-0.6
Placebo		Week 16	28.6	28.9	-0.3
Placebo		Week 2	28.7	28.9	-0.2
Placebo		Week 20	28.9	28.9	0.0
Placebo		Week 24	29.0	28.9	0.2
Placebo		Week 26	29.2	28.9	0.3
Placebo		Week 4	28.3	28.9	-0.6
Placebo		Week 6	28.4	28.9	-0.5
Placebo		Week 8	28.3	28.9	-0.6
Xanomeline Low Dose	01-716-1063	Week 12	28.2	28.3	-0.2
Xanomeline Low Dose		Week 2	28.7	28.3	0.4
Xanomeline Low Dose		Week 4	29.1	28.3	0.7
Xanomeline Low Dose		Week 6	28.2	28.3	-0.2
Xanomeline Low Dose		Week 8	28.3	28.3	0.0
Xanomeline High Dose	01-716-1071	Week 2	31.9	31.9	0.0
Xanomeline High Dose		Week 4	31.9	31.9	0.0
Xanomeline High Dose		Week 6	31.4	31.9	-0.6
Xanomeline High Dose		Week 8	31.2	31.9	-0.8
Xanomeline Low Dose	01-716-1094	Week 2	28.0	28.3	-0.3
Xanomeline Low Dose		Week 4	28.3	28.3	0.0
Xanomeline Low Dose	01-716-1103	Week 12	26.6	25.6	1.0
Xanomeline Low Dose		Week 16	26.2	25.6	0.6
Xanomeline Low Dose		Week 2	26.3	25.6	0.7
Xanomeline Low Dose		Week 20	26.5	25.6	0.8
Xanomeline Low Dose		Week 24	26.0	25.6	0.3
Xanomeline Low Dose		Week 26	26.6	25.6	1.0
Xanomeline Low Dose		Week 4	26.8	25.6	1.2
Xanomeline Low Dose		Week 6	27.0	25.6	1.3
Xanomeline Low Dose		Week 8	26.6	25.6	1.0
Placebo	01-716-1108	Week 12	27.1	26.0	1.1
Placebo		Week 16	27.1	26.0	1.1
Placebo		Week 2	26.9	26.0	0.9
Placebo		Week 20	26.2	26.0	0.2
Placebo		Week 24	27.1	26.0	1.1
Placebo		Week 26	27.0	26.0	1.0
Placebo		Week 4	26.9	26.0	0.9
Placebo		Week 6	26.9	26.0	0.9
Placebo		Week 8	26.9	26.0	0.9
Xanomeline Low Dose	01-716-1151	Week 12	18.9	19.7	-0.8
Xanomeline Low Dose		Week 2	19.3	19.7	-0.4
Xanomeline Low Dose		Week 4	19.1	19.7	-0.6
Xanomeline Low Dose		Week 6	18.9	19.7	-0.8
Xanomeline Low Dose		Week 8	19.3	19.7	-0.4
Xanomeline Low Dose	01-716-1157	Week 12	23.6	23.2	0.4
Xanomeline Low Dose		Week 16	23.9	23.2	0.7
Xanomeline Low Dose		Week 2	23.0	23.2	-0.2
Xanomeline Low Dose		Week 20	23.9	23.2	0.7
Xanomeline Low Dose		Week 24	23.9	23.2	0.7
Xanomeline Low Dose		Week 4	23.2	23.2	0.0
Xanomeline Low Dose		Week 6	23.9	23.2	0.7
Xanomeline Low Dose		Week 8	23.4	23.2	0.2
Placebo	01-716-1160	Week 12	24.0	24.1	-0.2
Placebo		Week 16	23.6	24.1	-0.6
Placebo		Week 2	23.8	24.1	-0.4
Placebo		Week 20	23.6	24.1	-0.6
Placebo		Week 24	23.8	24.1	-0.4
Placebo		Week 26	24.0	24.1	-0.2
Placebo		Week 4	24.0	24.1	-0.2
Placebo		Week 6	24.0	24.1	-0.2
Placebo		Week 8	23.8	24.1	-0.4
Xanomeline Low Dose	01-716-1167	Week 12	24.8	24.8	0.0
Xanomeline Low Dose		Week 16	24.5	24.8	-0.4
Xanomeline Low Dose		Week 2	24.8	24.8	0.0
Xanomeline Low Dose		Week 20	24.5	24.8	-0.4
Xanomeline Low Dose		Week 24	24.1	24.8	-0.7
Xanomeline Low Dose		Week 4	24.8	24.8	0.0
Xanomeline Low Dose		Week 6	24.8	24.8	0.0
Xanomeline Low Dose		Week 8	24.8	24.8	0.0
Placebo	01-716-1177	Week 12	26.0	27.3	-1.2
Placebo		Week 16	26.4	27.3	-0.9
Placebo		Week 2	27.8	27.3	0.6
Placebo		Week 20	26.7	27.3	-0.6
Placebo		Week 24	27.0	27.3	-0.3
Placebo		Week 26	27.3	27.3	0.0
Placebo		Week 4	26.7	27.3	-0.6
Placebo		Week 6	26.4	27.3	-0.9
Placebo		Week 8	26.4	27.3	-0.9
Xanomeline High Dose	01-716-1189	Week 12	26.7	27.4	-0.7
Xanomeline High Dose		Week 16	27.5	27.4	0.2
Xanomeline High Dose		Week 2	27.4	27.4	0.0
Xanomeline High Dose		Week 4	26.9	27.4	-0.5
Xanomeline High Dose		Week 6	26.9	27.4	-0.5
Xanomeline High Dose		Week 8	26.9	27.4	-0.5
Xanomeline High Dose	01-716-1229	Week 2	24.6	24.6	0.0
Xanomeline High Dose		Week 4	24.6	24.6	0.0
Xanomeline Low Dose	01-716-1298	Week 2	29.2	29.4	-0.2
Xanomeline Low Dose		Week 4	29.4	29.4	0.0
Xanomeline Low Dose		Week 6	29.6	29.4	0.3
Xanomeline Low Dose		Week 8	29.7	29.4	0.4
Placebo	01-716-1308	Week 2	23.0	23.6	-0.5
Placebo		Week 4	23.6	23.6	0.0
Placebo		Week 6	23.6	23.6	0.0
Xanomeline Low Dose	01-716-1311	Week 12	25.6	27.1	-1.4
Xanomeline Low Dose		Week 16	25.9	27.1	-1.1
Xanomeline Low Dose		Week 2	27.5	27.1	0.5
Xanomeline Low Dose		Week 4	26.9	27.1	-0.2
Xanomeline Low Dose		Week 6	26.1	27.1	-1.0
Xanomeline Low Dose		Week 8	26.5	27.1	-0.6
Xanomeline High Dose	01-716-1364	Week 12	20.1	20.4	-0.3
Xanomeline High Dose		Week 16	19.2	20.4	-1.2
Xanomeline High Dose		Week 2	20.4	20.4	0.0
Xanomeline High Dose		Week 20	19.6	20.4	-0.9
Xanomeline High Dose		Week 24	19.6	20.4	-0.9
Xanomeline High Dose		Week 26	19.6	20.4	-0.9
Xanomeline High Dose		Week 4	20.3	20.4	-0.1
Xanomeline High Dose		Week 6	20.3	20.4	-0.1
Xanomeline High Dose		Week 8	20.6	20.4	0.2
Xanomeline High Dose	01-716-1373	Week 2	32.6	32.0	0.6
Xanomeline High Dose		Week 4	33.2	32.0	1.3
Xanomeline High Dose		Week 6	33.0	32.0	1.0
Xanomeline High Dose		Week 8	33.4	32.0	1.5
Xanomeline High Dose	01-716-1418	Week 12	25.8	25.3	0.5
Xanomeline High Dose		Week 16	26.1	25.3	0.8
Xanomeline High Dose		Week 2	25.6	25.3	0.3
Xanomeline High Dose		Week 20	26.3	25.3	1.0
Xanomeline High Dose		Week 24	26.3	25.3	1.0
Xanomeline High Dose		Week 26	23.1	25.3	-2.2
Xanomeline High Dose		Week 4	25.8	25.3	0.5
Xanomeline High Dose		Week 6	26.1	25.3	0.8
Xanomeline High Dose		Week 8	26.2	25.3	0.9
Placebo	01-716-1441	Week 12	27.9	27.5	0.4
Placebo		Week 16	27.6	27.5	0.1
Placebo		Week 2	27.5	27.5	0.0
Placebo		Week 20	27.6	27.5	0.1
Placebo		Week 24	27.7	27.5	0.2
Placebo		Week 26	27.3	27.5	-0.2
Placebo		Week 4	27.5	27.5	0.0
Placebo		Week 6	27.3	27.5	-0.2
Placebo		Week 8	28.1	27.5	0.6
Xanomeline High Dose	01-716-1447	Week 12	24.2	24.2	0.0
Xanomeline High Dose		Week 16	24.6	24.2	0.4
Xanomeline High Dose		Week 2	24.6	24.2	0.4
Xanomeline High Dose		Week 20	24.6	24.2	0.4
Xanomeline High Dose		Week 24	24.4	24.2	0.2
Xanomeline High Dose		Week 26	24.3	24.2	0.1
Xanomeline High Dose		Week 4	25.0	24.2	0.8
Xanomeline High Dose		Week 6	24.4	24.2	0.2
Xanomeline High Dose		Week 8	24.4	24.2	0.2
Xanomeline Low Dose	01-717-1004	Week 12	30.9	30.2	0.7
Xanomeline Low Dose		Week 16	31.4	30.2	1.2
Xanomeline Low Dose		Week 2	29.5	30.2	-0.7
Xanomeline Low Dose		Week 20	31.4	30.2	1.2
Xanomeline Low Dose		Week 24	31.9	30.2	1.7
Xanomeline Low Dose		Week 26	31.9	30.2	1.7
Xanomeline Low Dose		Week 4	30.8	30.2	0.5
Xanomeline Low Dose		Week 6	30.2	30.2	0.0
Xanomeline Low Dose		Week 8	30.7	30.2	0.5
Xanomeline High Dose	01-717-1109	Week 12	23.7	13.7	10.0
Xanomeline High Dose		Week 16	23.9	13.7	10.2
Xanomeline High Dose		Week 2	24.3	13.7	10.6
Xanomeline High Dose		Week 20	23.9	13.7	10.2
Xanomeline High Dose		Week 24	23.9	13.7	10.3
Xanomeline High Dose		Week 26	25.0	13.7	11.4
Xanomeline High Dose		Week 4	24.1	13.7	10.5
Xanomeline High Dose		Week 6	24.4	13.7	10.7
Xanomeline High Dose		Week 8	23.9	13.7	10.2
Xanomeline High Dose	01-717-1174	Week 12	24.5	24.2	0.2
Xanomeline High Dose		Week 16	24.5	24.2	0.2
Xanomeline High Dose		Week 2	24.5	24.2	0.3
Xanomeline High Dose		Week 20	24.2	24.2	0.0
Xanomeline High Dose		Week 24	24.2	24.2	0.0
Xanomeline High Dose		Week 26	24.2	24.2	0.0
Xanomeline High Dose		Week 4	24.3	24.2	0.1
Xanomeline High Dose		Week 6	23.9	24.2	-0.3
Xanomeline High Dose		Week 8	24.1	24.2	-0.2
Placebo	01-717-1201	Week 2	26.9	26.6	0.4
Placebo		Week 4	26.9	26.6	0.4
Placebo		Week 6	26.9	26.6	0.4
Placebo		Week 8	26.6	26.6	0.0
Placebo	01-717-1344	Week 2	22.1	21.7	0.3
Placebo		Week 4	21.7	21.7	-0.0
Placebo		Week 6	22.1	21.7	0.3
Placebo		Week 8	21.6	21.7	-0.1
Xanomeline High Dose	01-717-1357	Week 12	25.0	24.6	0.4
Xanomeline High Dose		Week 16	25.3	24.6	0.7
Xanomeline High Dose		Week 2	24.6	24.6	-0.0
Xanomeline High Dose		Week 20	26.3	24.6	1.6
Xanomeline High Dose		Week 4	25.2	24.6	0.5
Xanomeline High Dose		Week 6	25.7	24.6	1.1
Xanomeline High Dose		Week 8	25.3	24.6	0.7
Xanomeline Low Dose	01-717-1446	Week 12	18.9	19.3	-0.5
Xanomeline Low Dose		Week 16	18.8	19.3	-0.6
Xanomeline Low Dose		Week 2	19.7	19.3	0.4
Xanomeline Low Dose		Week 20	18.9	19.3	-0.5
Xanomeline Low Dose		Week 24	18.7	19.3	-0.7
Xanomeline Low Dose		Week 4	19.4	19.3	0.1
Xanomeline Low Dose		Week 6	19.3	19.3	0.0
Xanomeline Low Dose		Week 8	19.0	19.3	-0.4
Xanomeline Low Dose	01-718-1079	Week 2	20.0	20.0	0.0
Xanomeline Low Dose		Week 4	20.3	20.0	0.4
Xanomeline High Dose	01-718-1101	Week 12	24.0	23.2	0.9
Xanomeline High Dose		Week 16	23.8	23.2	0.7
Xanomeline High Dose		Week 2	23.4	23.2	0.3
Xanomeline High Dose		Week 20	23.3	23.2	0.2
Xanomeline High Dose		Week 4	23.9	23.2	0.8
Xanomeline High Dose		Week 6	23.7	23.2	0.5
Xanomeline High Dose		Week 8	24.2	23.2	1.0
Placebo	01-718-1139	Week 12	22.3	22.4	-0.1
Placebo		Week 16	22.2	22.4	-0.2
Placebo		Week 2	23.0	22.4	0.6
Placebo		Week 20	22.7	22.4	0.3
Placebo		Week 24	22.1	22.4	-0.3
Placebo		Week 26	22.2	22.4	-0.2
Placebo		Week 4	22.4	22.4	0.0
Placebo		Week 6	22.5	22.4	0.2
Placebo		Week 8	22.4	22.4	0.0
Placebo	01-718-1150	Week 12	22.5	22.5	0.0
Placebo		Week 16	22.3	22.5	-0.2
Placebo		Week 20	22.5	22.5	0.0
Placebo		Week 24	22.5	22.5	-0.0
Placebo		Week 4	22.3	22.5	-0.2
Placebo		Week 8	21.6	22.5	-0.9
Xanomeline Low Dose	01-718-1170	Week 2	22.3	21.8	0.5
Placebo	01-718-1172	Week 12	22.3	21.9	0.4
Placebo		Week 2	22.0	21.9	0.1
Placebo		Week 4	22.0	21.9	0.1
Placebo		Week 6	22.4	21.9	0.6
Placebo		Week 8	22.0	21.9	0.1
Xanomeline Low Dose	01-718-1250	Week 12	22.9	23.6	-0.7
Xanomeline Low Dose		Week 16	23.2	23.6	-0.4
Xanomeline Low Dose		Week 2	23.6	23.6	0.0
Xanomeline Low Dose		Week 4	23.2	23.6	-0.4
Xanomeline Low Dose		Week 6	23.4	23.6	-0.2
Xanomeline Low Dose		Week 8	23.4	23.6	-0.2
Xanomeline Low Dose	01-718-1254	Week 12	28.7	28.3	0.3
Xanomeline Low Dose		Week 16	28.8	28.3	0.5
Xanomeline Low Dose		Week 2	28.6	28.3	0.2
Xanomeline Low Dose		Week 20	27.9	28.3	-0.5
Xanomeline Low Dose		Week 24	29.1	28.3	0.8
Xanomeline Low Dose		Week 26	29.4	28.3	1.1
Xanomeline Low Dose		Week 4	28.4	28.3	0.1
Xanomeline Low Dose		Week 6	28.7	28.3	0.4
Xanomeline Low Dose		Week 8	28.8	28.3	0.5
Xanomeline High Dose	01-718-1328	Week 2	22.4	21.9	0.5
Xanomeline High Dose		Week 4	23.0	21.9	1.1
Xanomeline High Dose		Week 6	21.9	21.9	0.0
Xanomeline High Dose		Week 8	21.9	21.9	0.0
Placebo	01-718-1355	Week 12	21.3	20.8	0.5
Placebo		Week 16	22.0	20.8	1.1
Placebo		Week 2	21.0	20.8	0.2
Placebo		Week 20	22.1	20.8	1.3
Placebo		Week 24	22.9	20.8	2.1
Placebo		Week 26	22.3	20.8	1.5
Placebo		Week 4	21.6	20.8	0.8
Placebo		Week 6	21.4	20.8	0.6
Placebo		Week 8	21.3	20.8	0.5
Xanomeline High Dose	01-718-1371	Week 2	27.8	27.8	0.0
Xanomeline High Dose		Week 4	28.0	27.8	0.2
Xanomeline High Dose		Week 6	27.4	27.8	-0.4
Xanomeline High Dose		Week 8	27.8	27.8	0.0
Xanomeline High Dose	01-718-1427	Week 2	20.0	20.5	-0.5
Xanomeline High Dose		Week 4	20.2	20.5	-0.3
Xanomeline High Dose		Week 6	20.1	20.5	-0.4

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

BSA

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	1.5	1.5	-0.0
Placebo		Week 16	1.5	1.5	-0.0
Placebo		Week 2	1.5	1.5	-0.0
Placebo		Week 20	1.5	1.5	-0.0
Placebo		Week 24	1.5	1.5	-0.0
Placebo		Week 26	1.5	1.5	-0.0
Placebo		Week 4	1.5	1.5	-0.0
Placebo		Week 6	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	-0.0
Placebo		Week 2	1.9	1.9	0.0
Xanomeline High Dose		Week 12	2.2	2.2	-0.0
Xanomeline High Dose		Week 16	2.2	2.2	0.0
Xanomeline High Dose		Week 2	2.2	2.2	0.0
Xanomeline High Dose		Week 20	2.2	2.2	0.0
Xanomeline High Dose		Week 24	2.2	2.2	0.0
Xanomeline High Dose		Week 26	2.2	2.2	0.0
Xanomeline High Dose		Week 4	2.2	2.2	-0.0
Xanomeline High Dose		Week 6	2.2	2.2	-0.0
Xanomeline High Dose		Week 8	2.2	2.2	0.0
Xanomeline High Dose		Week 12	1.6	1.6	0.0
Xanomeline High Dose		Week 16	1.7	1.6	0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 20	1.7	1.6	0.0
Xanomeline High Dose		Week 24	1.7	1.6	0.0
Xanomeline High Dose		Week 26	1.7	1.6	0.0
Xanomeline High Dose		Week 4	1.7	1.6	0.0
Xanomeline High Dose		Week 6	1.7	1.6	0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Placebo		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 12	1.9	1.9	0.0
Xanomeline Low Dose		Week 16	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 20	1.9	1.9	0.0
Xanomeline Low Dose		Week 24	1.9	1.9	0.0
Xanomeline Low Dose		Week 26	1.9	1.9	0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 6	1.9	1.9	0.0
Xanomeline Low Dose		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 4	2.0	2.0	-0.0
Xanomeline Low Dose		Week 6	2.0	2.0	-0.0
Xanomeline Low Dose		Week 8	2.0	2.0	-0.0
Placebo		Week 12	1.9	1.9	0.0
Placebo		Week 16	1.9	1.9	0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	0.0
Placebo		Week 12	1.9	1.9	-0.0
Placebo		Week 16	1.9	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	-0.0
Placebo		Week 24	1.9	1.9	-0.0
Placebo		Week 26	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	1.9	1.9	-0.0
Placebo		Week 8	1.9	1.9	0.0
Xanomeline High Dose		Week 12	1.9	1.8	0.0
Xanomeline High Dose		Week 16	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	-0.0
Xanomeline High Dose		Week 20	1.8	1.8	0.0
Xanomeline High Dose		Week 24	1.8	1.8	-0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	0.0
Xanomeline High Dose		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.5	1.5	0.0
Xanomeline High Dose		Week 4	1.5	1.5	0.0
Xanomeline High Dose		Week 12	2.1	2.1	0.0
Xanomeline High Dose		Week 16	2.1	2.1	0.0
Xanomeline High Dose		Week 2	2.1	2.1	0.0
Xanomeline High Dose		Week 20	2.1	2.1	0.0
Xanomeline High Dose		Week 24	2.1	2.1	0.0
Xanomeline High Dose		Week 26	2.1	2.1	0.0
Xanomeline High Dose		Week 4	2.1	2.1	0.0
Xanomeline High Dose		Week 6	2.1	2.1	0.0
Xanomeline High Dose		Week 8	2.1	2.1	0.0
Placebo		Week 12	1.6	1.6	-0.0
Placebo		Week 16	1.6	1.6	-0.0
Placebo		Week 2	1.6	1.6	-0.0
Placebo		Week 20	1.6	1.6	-0.0
Placebo		Week 24	1.6	1.6	-0.0
Placebo		Week 4	1.6	1.6	-0.0
Placebo		Week 6	1.6	1.6	-0.0
Placebo		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 2	2.1	2.1	0.0
Xanomeline High Dose		Week 4	2.1	2.1	-0.0
Xanomeline Low Dose		Week 2	2.2	2.2	0.0
Xanomeline Low Dose		Week 4	2.2	2.2	0.0
Xanomeline Low Dose		Week 12	1.6	1.6	0.0
Xanomeline Low Dose		Week 16	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 20	1.6	1.6	-0.0
Xanomeline Low Dose		Week 24	1.6	1.6	-0.0
Xanomeline Low Dose		Week 26	1.6	1.6	-0.0
Xanomeline Low Dose		Week 4	1.6	1.6	0.0
Xanomeline Low Dose		Week 6	1.7	1.6	0.0
Xanomeline Low Dose		Week 8	1.6	1.6	-0.0
Placebo		Week 12	1.7	1.7	0.0
Placebo		Week 16	1.7	1.7	0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	-0.0
Placebo		Week 24	1.7	1.7	-0.0
Placebo		Week 26	1.7	1.7	-0.0
Placebo		Week 4	1.7	1.7	-0.0
Placebo		Week 6	1.7	1.7	0.0
Placebo		Week 8	1.7	1.7	0.0
Xanomeline Low Dose		Week 2	1.4	1.4	0.0
Xanomeline Low Dose		Week 4	1.4	1.4	0.0
Xanomeline Low Dose		Week 6	1.4	1.4	0.0
Xanomeline Low Dose		Week 8	1.4	1.4	-0.0
Placebo		Week 12	2.0	2.0	-0.0
Placebo		Week 16	2.0	2.0	-0.0
Placebo		Week 2	2.0	2.0	0.0
Placebo		Week 20	2.0	2.0	0.0
Placebo		Week 24	2.0	2.0	-0.0
Placebo		Week 26	2.0	2.0	0.0
Placebo		Week 4	2.0	2.0	0.0
Placebo		Week 6	2.0	2.0	0.0
Placebo		Week 8	2.0	2.0	0.0
Xanomeline High Dose		Week 12	2.1	2.1	-0.0
Xanomeline High Dose		Week 16	2.1	2.1	-0.0
Xanomeline High Dose		Week 2	2.1	2.1	-0.0
Xanomeline High Dose		Week 20	2.1	2.1	0.0
Xanomeline High Dose		Week 24	2.1	2.1	0.0
Xanomeline High Dose		Week 4	2.1	2.1	-0.0
Xanomeline High Dose		Week 6	2.1	2.1	0.0
Xanomeline High Dose		Week 8	2.1	2.1	-0.0
Xanomeline High Dose		Week 12	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	0.0
Xanomeline High Dose		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 12	1.6	1.6	0.0
Xanomeline High Dose		Week 16	1.5	1.6	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 20	1.5	1.6	-0.0
Xanomeline High Dose		Week 24	1.5	1.6	-0.0
Xanomeline High Dose		Week 26	1.5	1.6	-0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline High Dose		Week 8	1.5	1.6	-0.0
Xanomeline Low Dose		Week 12	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 6	1.9	1.9	0.0
Xanomeline Low Dose		Week 8	1.9	1.9	0.0
Xanomeline High Dose		Week 12	2.0	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	-0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	-0.0
Xanomeline High Dose		Week 8	2.0	2.0	0.0
Xanomeline Low Dose		Week 12	1.8	1.8	-0.0
Xanomeline Low Dose		Week 16	1.8	1.8	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 20	1.8	1.8	0.0
Xanomeline Low Dose		Week 24	1.8	1.8	0.0
Xanomeline Low Dose		Week 26	1.8	1.8	0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Xanomeline Low Dose		Week 12	1.9	1.9	-0.0
Xanomeline Low Dose		Week 16	1.9	1.9	-0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 20	1.9	1.9	0.0
Xanomeline Low Dose		Week 24	1.9	1.9	-0.0
Xanomeline Low Dose		Week 26	1.9	1.9	-0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 6	1.9	1.9	-0.0
Xanomeline Low Dose		Week 8	1.9	1.9	-0.0
Xanomeline Low Dose		Week 2	1.7	1.8	-0.0
Placebo		Week 12	1.6	1.6	0.0
Placebo		Week 16	1.7	1.6	0.0
Placebo		Week 2	1.6	1.6	0.0
Placebo		Week 20	1.7	1.6	0.0
Placebo		Week 24	1.7	1.6	0.0
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.7	1.6	0.0
Placebo		Week 8	1.6	1.6	0.0
Placebo		Week 12	1.7	1.7	0.0
Placebo		Week 16	1.7	1.7	0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	0.0
Placebo		Week 24	1.7	1.7	0.0
Placebo		Week 26	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	0.0
Placebo		Week 6	1.7	1.7	0.0
Placebo		Week 8	1.7	1.7	0.0
Xanomeline High Dose		Week 12	2.0	2.0	-0.0
Xanomeline High Dose		Week 16	2.0	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 20	2.0	2.0	-0.0
Xanomeline High Dose		Week 24	1.9	2.0	-0.0
Xanomeline High Dose		Week 26	1.9	2.0	-0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	0.0
Xanomeline High Dose		Week 8	2.0	2.0	0.0
Placebo		Week 2	1.7	1.6	0.0
Placebo		Week 12	2.0	1.9	0.0
Placebo		Week 16	1.9	1.9	0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	0.0
Placebo		Week 12	1.9	1.9	0.0
Placebo		Week 16	2.0	1.9	0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	-0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	2.0	1.9	0.0
Placebo		Week 8	2.0	1.9	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	-0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	-0.0
Placebo		Week 4	1.5	1.5	-0.0
Placebo		Week 6	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	-0.0
Xanomeline Low Dose		Week 12	2.2	2.2	-0.0
Xanomeline Low Dose		Week 16	2.2	2.2	0.0
Xanomeline Low Dose		Week 2	2.2	2.2	-0.0
Xanomeline Low Dose		Week 20	2.2	2.2	0.0
Xanomeline Low Dose		Week 24	2.2	2.2	0.0
Xanomeline Low Dose		Week 26	2.2	2.2	-0.0
Xanomeline Low Dose		Week 4	2.2	2.2	-0.0
Xanomeline Low Dose		Week 6	2.2	2.2	0.0
Xanomeline Low Dose		Week 8	2.2	2.2	0.0
Xanomeline High Dose		Week 2	2.2	2.2	0.0
Xanomeline High Dose		Week 4	2.2	2.2	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Xanomeline Low Dose		Week 8	1.5	1.5	-0.0
Placebo		Week 12	1.9	1.9	0.0
Placebo		Week 16	1.9	1.9	0.0
Placebo		Week 2	1.9	1.9	-0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	1.9	1.9	-0.0
Placebo		Week 8	1.9	1.9	0.0
Xanomeline High Dose		Week 12	2.0	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	0.0
Xanomeline High Dose		Week 8	2.0	2.0	0.0
Xanomeline Low Dose		Week 12	2.3	2.3	-0.0
Xanomeline Low Dose		Week 2	2.3	2.3	0.0
Xanomeline Low Dose		Week 4	2.3	2.3	0.0
Xanomeline Low Dose		Week 6	2.3	2.3	-0.0
Xanomeline Low Dose		Week 8	2.3	2.3	-0.0
Placebo		Week 2	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 12	1.7	1.7	0.0
Placebo		Week 16	1.7	1.7	0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	0.1
Placebo		Week 24	1.7	1.7	0.0
Placebo		Week 26	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	0.0
Placebo		Week 6	1.7	1.7	0.0
Placebo		Week 8	1.7	1.7	0.0
Xanomeline Low Dose		Week 12	1.5	1.4	0.1
Xanomeline Low Dose		Week 16	1.5	1.4	0.1
Xanomeline Low Dose		Week 2	1.5	1.4	0.1
Xanomeline Low Dose		Week 4	1.5	1.4	0.1
Xanomeline Low Dose		Week 6	1.5	1.4	0.1
Xanomeline Low Dose		Week 8	1.5	1.4	0.1
Xanomeline Low Dose		Week 2	1.8	1.8	-0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	0.0
Placebo		Week 12	1.4	1.4	-0.0
Placebo		Week 16	1.4	1.4	-0.1
Placebo		Week 2	1.4	1.4	-0.0
Placebo		Week 20	1.4	1.4	-0.0
Placebo		Week 24	1.4	1.4	-0.1
Placebo		Week 26	1.4	1.4	-0.1
Placebo		Week 4	1.4	1.4	-0.0
Placebo		Week 6	1.4	1.4	-0.0
Placebo		Week 8	1.4	1.4	-0.0
Xanomeline High Dose		Week 12	1.6	1.6	-0.0
Xanomeline High Dose		Week 16	1.6	1.6	0.0
Xanomeline High Dose		Week 2	1.6	1.6	-0.0
Xanomeline High Dose		Week 20	1.6	1.6	-0.0
Xanomeline High Dose		Week 24	1.6	1.6	-0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 12	1.6	1.6	0.0
Xanomeline High Dose		Week 16	1.5	1.6	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Placebo		Week 12	1.4	1.4	0.0
Placebo		Week 16	1.4	1.4	0.0
Placebo		Week 2	1.4	1.4	0.0
Placebo		Week 20	1.4	1.4	-0.0
Placebo		Week 24	1.4	1.4	-0.0
Placebo		Week 26	1.4	1.4	-0.0
Placebo		Week 4	1.4	1.4	-0.0
Placebo		Week 6	1.4	1.4	-0.0
Placebo		Week 8	1.4	1.4	0.0
Xanomeline High Dose		Week 2	1.5	1.5	-0.0
Xanomeline High Dose		Week 4	1.5	1.5	-0.0
Xanomeline Low Dose		Week 12	1.9	1.8	0.0
Xanomeline Low Dose		Week 16	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 20	1.8	1.8	-0.0
Xanomeline Low Dose		Week 24	1.8	1.8	-0.1
Xanomeline Low Dose		Week 26	1.8	1.8	-0.1
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.9	1.8	0.0
Xanomeline Low Dose		Week 8	1.9	1.8	0.0
Xanomeline High Dose		Week 12	1.7	1.7	-0.0
Xanomeline High Dose		Week 16	1.7	1.7	0.0
Xanomeline High Dose		Week 2	1.7	1.7	-0.0
Xanomeline High Dose		Week 20	1.7	1.7	0.0
Xanomeline High Dose		Week 24	1.7	1.7	-0.0
Xanomeline High Dose		Week 26	1.7	1.7	0.0
Xanomeline High Dose		Week 4	1.7	1.7	0.0
Xanomeline High Dose		Week 6	1.7	1.7	-0.0
Xanomeline High Dose		Week 8	1.7	1.7	-0.0
Xanomeline High Dose		Week 2	1.4	1.4	0.0
Xanomeline High Dose		Week 4	1.4	1.4	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	-0.0
Placebo		Week 12	2.0	2.0	-0.0
Placebo		Week 16	2.0	2.0	-0.0
Placebo		Week 2	2.0	2.0	-0.0
Placebo		Week 4	2.0	2.0	-0.0
Placebo		Week 6	2.0	2.0	-0.0
Placebo		Week 8	2.0	2.0	-0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 4	2.0	2.0	-0.0
Xanomeline High Dose		Week 6	2.0	2.0	-0.0
Xanomeline High Dose		Week 8	2.0	2.0	-0.0
Xanomeline High Dose		Week 2	1.9	1.9	0.0
Xanomeline High Dose		Week 4	1.9	1.9	-0.0
Xanomeline High Dose		Week 6	1.9	1.9	0.0
Xanomeline High Dose		Week 12	1.9	1.9	-0.0
Xanomeline High Dose		Week 2	1.9	1.9	0.0
Xanomeline High Dose		Week 4	1.9	1.9	0.0
Xanomeline High Dose		Week 6	1.9	1.9	0.0
Xanomeline High Dose		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 12	1.9	1.9	0.0
Xanomeline Low Dose		Week 16	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	-0.0
Xanomeline Low Dose		Week 20	1.9	1.9	0.0
Xanomeline Low Dose		Week 4	1.9	1.9	-0.0
Xanomeline Low Dose		Week 6	1.9	1.9	0.0
Xanomeline Low Dose		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.4	1.5	-0.0
Xanomeline Low Dose		Week 4	1.4	1.5	-0.1
Xanomeline Low Dose		Week 6	1.4	1.5	-0.0
Xanomeline Low Dose		Week 8	1.4	1.5	-0.0
Placebo		Week 12	1.4	1.4	0.0
Placebo		Week 16	1.4	1.4	0.0
Placebo		Week 2	1.4	1.4	0.0
Placebo		Week 20	1.4	1.4	0.0
Placebo		Week 24	1.4	1.4	0.0
Placebo		Week 26	1.4	1.4	0.0
Placebo		Week 4	1.4	1.4	0.0
Placebo		Week 6	1.4	1.4	0.0
Placebo		Week 8	1.4	1.4	0.0
Xanomeline Low Dose		Week 12	1.7	1.7	-0.0
Xanomeline Low Dose		Week 16	1.7	1.7	-0.0
Xanomeline Low Dose		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 20	1.7	1.7	-0.0
Xanomeline Low Dose		Week 24	1.7	1.7	-0.0
Xanomeline Low Dose		Week 26	1.7	1.7	-0.0
Xanomeline Low Dose		Week 4	1.7	1.7	0.0
Xanomeline Low Dose		Week 6	1.7	1.7	0.0
Xanomeline Low Dose		Week 8	1.7	1.7	-0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	-0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	0.0
Placebo		Week 4	1.5	1.5	-0.0
Placebo		Week 6	1.5	1.5	0.0
Placebo		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	0.0
Xanomeline Low Dose		Week 16	1.5	1.5	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 20	1.5	1.5	0.0
Xanomeline Low Dose		Week 24	1.5	1.5	0.0
Xanomeline Low Dose		Week 26	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	-0.0
Xanomeline Low Dose		Week 8	1.5	1.5	0.0
Placebo		Week 2	1.4	1.4	0.0
Xanomeline High Dose		Week 2	1.9	1.9	0.0
Xanomeline High Dose		Week 4	1.9	1.9	0.0
Xanomeline High Dose		Week 6	1.9	1.9	0.0
Placebo		Week 2	1.5	1.5	-0.0
Placebo		Week 4	1.5	1.5	-0.0
Placebo		Week 6	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	-0.0
Xanomeline High Dose		Week 2	2.1	2.1	-0.0
Xanomeline High Dose		Week 4	2.1	2.1	-0.0
Xanomeline High Dose		Week 6	2.1	2.1	-0.0
Xanomeline High Dose		Week 8	2.1	2.1	-0.0
Xanomeline Low Dose		Week 2	1.7	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	-0.0
Xanomeline Low Dose		Week 2	1.8	1.8	-0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	-0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.9	1.9	-0.0
Xanomeline High Dose		Week 4	1.9	1.9	0.0
Xanomeline High Dose		Week 6	1.9	1.9	-0.0
Xanomeline High Dose		Week 8	1.9	1.9	-0.0
Placebo		Week 12	1.9	1.9	-0.0
Placebo		Week 16	1.9	1.9	0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	0.0
Placebo		Week 12	1.7	1.7	-0.0
Placebo		Week 16	1.7	1.7	-0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	-0.0
Placebo		Week 24	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	-0.0
Placebo		Week 6	1.7	1.7	-0.0
Placebo		Week 8	1.7	1.7	0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 12	1.9	1.9	-0.0
Placebo		Week 16	1.9	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	-0.0
Placebo		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Placebo		Week 12	1.6	1.6	0.0
Placebo		Week 16	1.6	1.6	0.0
Placebo		Week 2	1.6	1.6	0.0
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.6	1.6	0.0
Placebo		Week 8	1.6	1.6	0.0
Placebo		Week 2	1.2	1.3	-0.0
Xanomeline High Dose		Week 12	1.7	1.7	-0.0
Xanomeline High Dose		Week 16	1.7	1.7	-0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline High Dose		Week 20	1.7	1.7	-0.0
Xanomeline High Dose		Week 24	1.7	1.7	-0.0
Xanomeline High Dose		Week 26	1.7	1.7	-0.0
Xanomeline High Dose		Week 4	1.7	1.7	-0.0
Xanomeline High Dose		Week 6	1.7	1.7	-0.0
Xanomeline High Dose		Week 8	1.7	1.7	-0.0
Xanomeline High Dose		Week 12	1.7	1.8	-0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	-0.0
Xanomeline High Dose		Week 8	1.8	1.8	-0.0
Placebo		Week 12	1.8	1.8	-0.0
Placebo		Week 16	1.8	1.8	-0.0
Placebo		Week 2	1.8	1.8	-0.0
Placebo		Week 20	1.7	1.8	-0.1
Placebo		Week 24	1.8	1.8	0.0
Placebo		Week 26	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	-0.0
Xanomeline Low Dose		Week 12	1.9	1.9	-0.0
Xanomeline Low Dose		Week 16	1.8	1.9	-0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 20	1.9	1.9	-0.0
Xanomeline Low Dose		Week 24	1.9	1.9	-0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 6	1.9	1.9	-0.0
Xanomeline Low Dose		Week 8	1.9	1.9	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 12	1.4	1.4	-0.0
Xanomeline High Dose		Week 2	1.4	1.4	0.0
Xanomeline High Dose		Week 4	1.4	1.4	0.0
Xanomeline High Dose		Week 6	1.4	1.4	0.0
Xanomeline High Dose		Week 8	1.4	1.4	-0.0
Placebo		Week 12	1.5	1.3	0.2
Placebo		Week 16	1.5	1.3	0.2
Placebo		Week 2	1.3	1.3	-0.0
Placebo		Week 20	1.4	1.3	0.1
Placebo		Week 24	1.5	1.3	0.1
Placebo		Week 26	1.3	1.3	-0.0
Placebo		Week 4	1.3	1.3	-0.0
Placebo		Week 6	1.3	1.3	-0.0
Placebo		Week 8	1.3	1.3	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	-0.0
Xanomeline Low Dose		Week 12	1.5	1.5	-0.0
Xanomeline Low Dose		Week 16	1.5	1.5	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	-0.0
Xanomeline Low Dose		Week 6	1.5	1.5	-0.0
Xanomeline Low Dose		Week 8	1.5	1.5	-0.0
Xanomeline Low Dose		Week 12	1.5	1.5	0.0
Xanomeline Low Dose		Week 16	1.5	1.5	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 20	1.5	1.5	0.0
Xanomeline Low Dose		Week 24	1.5	1.5	0.0
Xanomeline Low Dose		Week 26	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Xanomeline Low Dose		Week 8	1.5	1.5	0.0
Placebo		Week 12	1.6	1.7	-0.1
Placebo		Week 16	1.6	1.7	-0.1
Placebo		Week 2	1.6	1.7	-0.0
Placebo		Week 20	1.6	1.7	-0.1
Placebo		Week 24	1.6	1.7	-0.1
Placebo		Week 4	1.6	1.7	-0.0
Placebo		Week 6	1.6	1.7	-0.1
Placebo		Week 8	1.6	1.7	-0.1
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 4	1.7	1.6	0.0
Placebo		Week 12	1.9	1.9	0.0
Placebo		Week 16	1.9	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	-0.0
Placebo		Week 24	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	-0.0
Xanomeline Low Dose		Week 16	1.5	1.5	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	-0.0
Xanomeline Low Dose		Week 20	1.5	1.5	0.0
Xanomeline Low Dose		Week 24	1.5	1.5	0.0
Xanomeline Low Dose		Week 26	1.6	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	-0.0
Xanomeline Low Dose		Week 6	1.5	1.5	-0.0
Xanomeline Low Dose		Week 8	1.6	1.5	0.0
Placebo		Week 12	1.8	1.7	0.1
Placebo		Week 16	1.8	1.7	0.1
Placebo		Week 20	1.8	1.7	0.1
Placebo		Week 24	1.8	1.7	0.0
Placebo		Week 26	1.8	1.7	0.1
Placebo		Week 4	1.8	1.7	0.1
Placebo		Week 6	1.8	1.7	0.1
Placebo		Week 8	1.8	1.7	0.1
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 12	1.6	1.6	0.0
Placebo		Week 16	1.6	1.6	0.0
Placebo		Week 2	1.6	1.6	-0.0
Placebo		Week 20	1.6	1.6	0.1
Placebo		Week 24	1.6	1.6	0.1
Placebo		Week 26	1.6	1.6	0.1
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.6	1.6	0.0
Placebo		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 12	1.7	1.7	0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline High Dose		Week 4	1.7	1.7	0.0
Xanomeline High Dose		Week 6	1.7	1.7	0.0
Xanomeline High Dose		Week 8	1.7	1.7	0.0
Xanomeline Low Dose		Week 2	1.4	1.4	0.0
Xanomeline High Dose		Week 2	1.9	1.9	0.0
Xanomeline High Dose		Week 4	1.9	1.9	0.0
Placebo		Week 12	2.0	2.0	0.0
Placebo		Week 16	2.0	2.0	0.0
Placebo		Week 2	2.0	2.0	0.0
Placebo		Week 20	2.0	2.0	0.0
Placebo		Week 24	2.0	2.0	0.0
Placebo		Week 26	2.0	2.0	-0.0
Placebo		Week 4	2.0	2.0	0.0
Placebo		Week 6	2.0	2.0	0.0
Placebo		Week 8	2.0	2.0	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 4	1.9	1.9	-0.0
Xanomeline Low Dose		Week 6	1.9	1.9	0.0
Placebo		Week 12	1.8	1.8	0.0
Placebo		Week 16	1.8	1.8	0.0
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 20	1.8	1.8	0.0
Placebo		Week 24	1.8	1.8	-0.0
Placebo		Week 26	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	0.0
Placebo		Week 12	1.9	2.0	-0.0
Placebo		Week 16	1.9	2.0	-0.0
Placebo		Week 2	2.0	2.0	0.0
Placebo		Week 20	1.9	2.0	-0.0
Placebo		Week 24	1.9	2.0	-0.0
Placebo		Week 26	1.9	2.0	-0.0
Placebo		Week 4	1.9	2.0	-0.0
Placebo		Week 6	1.9	2.0	-0.0
Placebo		Week 8	1.9	2.0	-0.0
Xanomeline Low Dose		Week 12	2.1	2.0	0.1
Xanomeline Low Dose		Week 2	2.1	2.0	0.0
Xanomeline Low Dose		Week 4	2.1	2.0	0.0
Xanomeline Low Dose		Week 6	2.1	2.0	0.0
Xanomeline Low Dose		Week 8	2.1	2.0	0.1
Placebo		Week 12	1.6	1.6	-0.0
Placebo		Week 16	1.6	1.6	0.0
Placebo		Week 2	1.6	1.6	0.0
Placebo		Week 20	1.6	1.6	-0.0
Placebo		Week 24	1.6	1.6	0.0
Placebo		Week 26	1.6	1.6	0.0
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.6	1.6	-0.0
Placebo		Week 8	1.6	1.6	-0.0
Xanomeline High Dose		Week 12	2.1	2.2	-0.0
Xanomeline High Dose		Week 16	2.1	2.2	-0.0
Xanomeline High Dose		Week 2	2.2	2.2	0.0
Xanomeline High Dose		Week 20	2.1	2.2	-0.0
Xanomeline High Dose		Week 24	2.1	2.2	-0.1
Xanomeline High Dose		Week 26	2.1	2.2	-0.0
Xanomeline High Dose		Week 4	2.1	2.2	-0.0
Xanomeline High Dose		Week 6	2.1	2.2	-0.0
Xanomeline High Dose		Week 8	2.1	2.2	-0.0
Placebo		Week 12	1.7	1.7	0.0
Placebo		Week 16	1.7	1.7	0.0
Placebo		Week 2	1.7	1.7	-0.0
Placebo		Week 20	1.7	1.7	0.0
Placebo		Week 24	1.7	1.7	-0.0
Placebo		Week 26	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	-0.0
Placebo		Week 6	1.7	1.7	-0.0
Placebo		Week 8	1.7	1.7	-0.0
Xanomeline High Dose		Week 12	1.9	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	0.0
Xanomeline High Dose		Week 8	1.9	1.8	0.0
Xanomeline Low Dose		Week 12	1.6	1.6	0.0
Xanomeline Low Dose		Week 16	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 20	1.6	1.6	-0.0
Xanomeline Low Dose		Week 24	1.6	1.6	-0.0
Xanomeline Low Dose		Week 26	1.7	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	0.0
Xanomeline Low Dose		Week 6	1.7	1.6	0.0
Xanomeline Low Dose		Week 8	1.7	1.6	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Placebo		Week 12	1.8	1.8	0.0
Placebo		Week 16	1.8	1.8	-0.0
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 20	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 12	1.6	1.5	0.0
Xanomeline High Dose		Week 16	1.6	1.5	0.0
Xanomeline High Dose		Week 2	1.6	1.5	0.0
Xanomeline High Dose		Week 20	1.6	1.5	0.0
Xanomeline High Dose		Week 24	1.6	1.5	0.0
Xanomeline High Dose		Week 26	1.6	1.5	0.0
Xanomeline High Dose		Week 4	1.6	1.5	0.0
Xanomeline High Dose		Week 6	1.6	1.5	0.0
Xanomeline High Dose		Week 8	1.6	1.5	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	0.0
Placebo		Week 12	1.9	1.9	0.0
Placebo		Week 16	1.8	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.8	1.9	-0.0
Placebo		Week 24	1.8	1.9	-0.0
Placebo		Week 26	1.8	1.9	-0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	-0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	-0.0
Xanomeline Low Dose		Week 16	1.4	1.5	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 20	1.5	1.5	-0.0
Xanomeline Low Dose		Week 24	1.5	1.5	-0.0
Xanomeline Low Dose		Week 26	1.4	1.5	-0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	-0.0
Xanomeline Low Dose		Week 8	1.5	1.5	-0.0
Xanomeline High Dose		Week 12	1.8	1.8	0.0
Xanomeline High Dose		Week 16	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 20	1.8	1.8	-0.0
Xanomeline High Dose		Week 24	1.8	1.8	-0.0
Xanomeline High Dose		Week 26	1.8	1.8	-0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	0.0
Xanomeline High Dose		Week 8	1.8	1.8	0.0
Xanomeline Low Dose		Week 12	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	-0.0
Xanomeline Low Dose		Week 6	1.6	1.6	-0.0
Xanomeline Low Dose		Week 8	1.6	1.6	0.0
Placebo		Week 12	2.0	2.0	-0.0
Placebo		Week 16	2.0	2.0	-0.0
Placebo		Week 2	2.0	2.0	-0.0
Placebo		Week 20	1.9	2.0	-0.0
Placebo		Week 24	1.9	2.0	-0.0
Placebo		Week 26	1.9	2.0	-0.1
Placebo		Week 4	2.0	2.0	0.0
Placebo		Week 6	2.0	2.0	0.0
Placebo		Week 8	2.0	2.0	-0.0
Xanomeline High Dose		Week 12	1.6	1.6	0.0
Xanomeline High Dose		Week 16	1.6	1.6	0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 20	1.6	1.6	-0.0
Xanomeline High Dose		Week 24	1.6	1.6	0.0
Xanomeline High Dose		Week 26	1.5	1.6	-0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 4	2.0	2.0	-0.0
Xanomeline Low Dose		Week 6	2.0	2.0	-0.0
Xanomeline Low Dose		Week 8	2.0	2.0	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline Low Dose		Week 12	1.8	1.8	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 2	2.0	2.0	-0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	-0.0
Xanomeline High Dose		Week 8	1.9	2.0	-0.1
Placebo		Week 12	1.8	1.8	0.0
Placebo		Week 16	1.8	1.8	0.0
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 20	1.8	1.8	0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	0.0
Xanomeline Low Dose		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 4	1.8	1.7	0.0
Xanomeline Low Dose		Week 6	1.8	1.7	0.0
Xanomeline Low Dose		Week 8	1.8	1.7	0.0
Placebo		Week 12	1.4	1.4	-0.0
Placebo		Week 16	1.4	1.4	-0.0
Placebo		Week 2	1.4	1.4	-0.0
Placebo		Week 20	1.4	1.4	-0.0
Placebo		Week 24	1.4	1.4	-0.0
Placebo		Week 26	1.4	1.4	-0.0
Placebo		Week 4	1.4	1.4	0.0
Placebo		Week 6	1.4	1.4	0.0
Placebo		Week 8	1.4	1.4	0.0
Placebo		Week 12	1.4	1.4	0.0
Placebo		Week 16	1.4	1.4	-0.0
Placebo		Week 2	1.4	1.4	0.0
Placebo		Week 4	1.4	1.4	0.0
Placebo		Week 6	1.4	1.4	0.0
Placebo		Week 8	1.4	1.4	0.0
Xanomeline High Dose		Week 12	2.0	2.0	-0.0
Xanomeline High Dose		Week 16	2.0	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 20	2.0	2.0	0.0
Xanomeline High Dose		Week 24	2.0	2.0	-0.0
Xanomeline High Dose		Week 26	2.0	2.0	-0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	0.0
Xanomeline High Dose		Week 8	2.0	2.0	0.0
Placebo		Week 12	1.6	1.5	0.0
Placebo		Week 16	1.6	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 20	1.6	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	-0.0
Placebo		Week 4	1.6	1.5	0.0
Placebo		Week 6	1.6	1.5	0.0
Placebo		Week 8	1.6	1.5	0.0
Xanomeline Low Dose		Week 12	1.8	1.8	-0.0
Xanomeline Low Dose		Week 16	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 20	1.8	1.8	-0.0
Xanomeline Low Dose		Week 24	1.8	1.8	-0.1
Xanomeline Low Dose		Week 26	1.8	1.8	-0.1
Xanomeline Low Dose		Week 4	1.8	1.8	-0.0
Xanomeline Low Dose		Week 6	1.8	1.8	-0.0
Xanomeline Low Dose		Week 8	1.8	1.8	-0.0
Placebo		Week 12	2.0	1.9	0.0
Placebo		Week 16	2.0	1.9	0.0
Placebo		Week 2	1.9	1.9	-0.0
Placebo		Week 20	2.0	1.9	0.0
Placebo		Week 24	2.0	1.9	0.0
Placebo		Week 26	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	2.0	1.9	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 12	1.8	1.9	-0.0
Xanomeline High Dose		Week 16	1.8	1.9	-0.0
Xanomeline High Dose		Week 2	1.8	1.9	-0.0
Xanomeline High Dose		Week 20	1.8	1.9	-0.0
Xanomeline High Dose		Week 24	1.8	1.9	-0.0
Xanomeline High Dose		Week 4	1.8	1.9	-0.0
Xanomeline High Dose		Week 6	1.9	1.9	0.1
Xanomeline High Dose		Week 8	1.8	1.9	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	-0.0
Xanomeline High Dose		Week 4	1.6	1.6	-0.0
Placebo		Week 12	1.8	1.8	-0.0
Placebo		Week 16	1.8	1.8	-0.0
Placebo		Week 2	1.8	1.8	-0.0
Placebo		Week 20	1.8	1.8	-0.0
Placebo		Week 24	1.8	1.8	-0.0
Placebo		Week 26	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	-0.0
Placebo		Week 6	1.8	1.8	-0.0
Placebo		Week 8	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	-0.1
Xanomeline Low Dose		Week 6	1.6	1.6	-0.0
Xanomeline Low Dose		Week 8	1.6	1.6	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	-0.0
Xanomeline Low Dose		Week 4	1.5	1.5	-0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Placebo		Week 12	1.9	1.9	-0.0
Placebo		Week 16	1.9	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	-0.0
Placebo		Week 24	1.9	1.9	-0.0
Placebo		Week 26	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	-0.0
Placebo		Week 8	1.9	1.9	-0.0
Xanomeline High Dose		Week 12	1.4	1.4	0.0
Xanomeline High Dose		Week 16	1.4	1.4	-0.0
Xanomeline High Dose		Week 2	1.5	1.4	0.0
Xanomeline High Dose		Week 4	1.4	1.4	0.0
Xanomeline High Dose		Week 6	1.5	1.4	0.0
Xanomeline High Dose		Week 8	1.4	1.4	0.0
Placebo		Week 12	1.5	1.5	0.1
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	0.0
Placebo		Week 4	1.5	1.5	0.0
Placebo		Week 6	1.5	1.5	0.0
Placebo		Week 8	1.5	1.5	0.1
Placebo		Week 12	1.3	1.3	0.0
Placebo		Week 16	1.3	1.3	-0.0
Placebo		Week 2	1.3	1.3	0.0
Placebo		Week 20	1.3	1.3	-0.0
Placebo		Week 24	1.3	1.3	-0.0
Placebo		Week 26	1.3	1.3	-0.0
Placebo		Week 4	1.3	1.3	0.0
Placebo		Week 6	1.3	1.3	0.0
Placebo		Week 8	1.3	1.3	0.0
Xanomeline High Dose		Week 2	1.7	1.7	-0.0
Xanomeline High Dose		Week 4	1.7	1.7	-0.0
Xanomeline High Dose		Week 6	1.7	1.7	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	-0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.6	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	-0.0
Xanomeline Low Dose		Week 8	1.5	1.5	-0.0
Placebo		Week 12	1.4	1.4	0.0
Placebo		Week 16	1.4	1.4	0.0
Placebo		Week 2	1.4	1.4	0.0
Placebo		Week 20	1.4	1.4	0.0
Placebo		Week 24	1.4	1.4	-0.0
Placebo		Week 26	1.4	1.4	-0.0
Placebo		Week 4	1.4	1.4	0.0
Placebo		Week 6	1.4	1.4	0.0
Placebo		Week 8	1.4	1.4	0.0
Xanomeline High Dose		Week 12	1.5	1.5	0.0
Xanomeline High Dose		Week 16	1.5	1.5	0.0
Xanomeline High Dose		Week 2	1.5	1.5	0.0
Xanomeline High Dose		Week 20	1.5	1.5	0.0
Xanomeline High Dose		Week 24	1.5	1.5	0.0
Xanomeline High Dose		Week 26	1.5	1.5	0.0
Xanomeline High Dose		Week 4	1.5	1.5	-0.0
Xanomeline High Dose		Week 6	1.5	1.5	-0.0
Xanomeline High Dose		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 12	2.1	2.1	0.0
Xanomeline Low Dose		Week 16	2.1	2.1	-0.0
Xanomeline Low Dose		Week 2	2.1	2.1	0.0
Xanomeline Low Dose		Week 20	2.1	2.1	-0.0
Xanomeline Low Dose		Week 24	2.1	2.1	-0.0
Xanomeline Low Dose		Week 26	2.1	2.1	-0.1
Xanomeline Low Dose		Week 4	2.1	2.1	0.0
Xanomeline Low Dose		Week 6	2.1	2.1	-0.0
Xanomeline Low Dose		Week 8	2.1	2.1	-0.0
Xanomeline High Dose		Week 12	2.0	2.0	0.0
Xanomeline High Dose		Week 16	2.0	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 20	2.0	2.0	0.0
Xanomeline High Dose		Week 24	2.0	2.0	0.0
Xanomeline High Dose		Week 26	2.0	2.0	0.0
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.0	2.0	0.0
Xanomeline High Dose		Week 8	2.0	2.0	0.0
Placebo		Week 12	1.9	1.9	-0.0
Placebo		Week 16	1.9	1.9	0.0
Placebo		Week 2	1.9	1.9	-0.0
Placebo		Week 4	1.9	1.9	-0.0
Placebo		Week 6	1.9	1.9	-0.0
Placebo		Week 8	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.6	1.5	0.0
Placebo		Week 2	1.4	1.4	0.0
Placebo		Week 4	1.4	1.4	0.0
Placebo		Week 6	1.4	1.4	0.0
Xanomeline High Dose		Week 2	1.9	1.9	-0.0
Xanomeline High Dose		Week 4	1.9	1.9	0.0
Xanomeline High Dose		Week 6	1.9	1.9	0.0
Xanomeline High Dose		Week 8	1.9	1.9	-0.0
Xanomeline Low Dose		Week 2	1.4	1.4	0.0
Xanomeline Low Dose		Week 4	1.4	1.4	0.0
Xanomeline Low Dose		Week 6	1.4	1.4	0.0
Xanomeline Low Dose		Week 8	1.4	1.4	0.0
Placebo		Week 2	1.3	1.3	0.0
Placebo		Week 4	1.3	1.3	-0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 4	1.5	1.5	0.0
Placebo		Week 6	1.5	1.5	0.0
Placebo		Week 8	1.5	1.5	-0.0
Xanomeline High Dose		Week 12	2.1	2.1	0.0
Xanomeline High Dose		Week 16	2.1	2.1	-0.0
Xanomeline High Dose		Week 2	2.1	2.1	0.0
Xanomeline High Dose		Week 20	2.1	2.1	-0.0
Xanomeline High Dose		Week 24	2.1	2.1	-0.0
Xanomeline High Dose		Week 26	2.1	2.1	-0.0
Xanomeline High Dose		Week 4	2.1	2.1	0.0
Xanomeline High Dose		Week 6	2.1	2.1	-0.0
Xanomeline High Dose		Week 8	2.1	2.1	0.0
Xanomeline Low Dose		Week 12	1.9	1.9	0.0
Xanomeline Low Dose		Week 16	1.9	1.9	0.0
Xanomeline Low Dose		Week 2	1.9	1.9	0.0
Xanomeline Low Dose		Week 20	1.9	1.9	-0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 6	1.9	1.9	0.0
Xanomeline Low Dose		Week 8	1.9	1.9	0.0
Placebo		Week 12	1.2	1.2	0.0
Placebo		Week 16	1.2	1.2	-0.0
Placebo		Week 2	1.2	1.2	-0.0
Placebo		Week 20	1.2	1.2	-0.0
Placebo		Week 24	1.2	1.2	0.0
Placebo		Week 26	1.2	1.2	0.0
Placebo		Week 4	1.2	1.2	0.0
Placebo		Week 6	1.2	1.2	0.0
Placebo		Week 8	1.2	1.2	0.0
Xanomeline Low Dose		Week 12	2.1	2.1	0.0
Xanomeline Low Dose		Week 16	2.1	2.1	0.0
Xanomeline Low Dose		Week 2	2.1	2.1	0.0
Xanomeline Low Dose		Week 4	2.1	2.1	-0.0
Xanomeline Low Dose		Week 6	2.1	2.1	-0.0
Xanomeline Low Dose		Week 8	2.1	2.1	-0.0
Xanomeline High Dose		Week 12	2.3	2.3	-0.0
Xanomeline High Dose		Week 16	2.3	2.3	-0.0
Xanomeline High Dose		Week 2	2.3	2.3	-0.0
Xanomeline High Dose		Week 20	2.3	2.3	-0.0
Xanomeline High Dose		Week 24	2.3	2.3	-0.0
Xanomeline High Dose		Week 26	2.3	2.3	-0.0
Xanomeline High Dose		Week 4	2.3	2.3	-0.0
Xanomeline High Dose		Week 6	2.3	2.3	-0.0
Xanomeline High Dose		Week 8	2.3	2.3	-0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Placebo		Week 12	1.8	1.8	-0.0
Placebo		Week 16	1.8	1.8	0.0
Placebo		Week 2	1.8	1.8	-0.0
Placebo		Week 20	1.8	1.8	-0.0
Placebo		Week 24	1.8	1.8	-0.0
Placebo		Week 26	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	-0.0
Placebo		Week 6	1.8	1.8	-0.0
Placebo		Week 8	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 4	1.7	1.7	0.0
Xanomeline Low Dose		Week 6	1.7	1.7	0.0
Xanomeline Low Dose		Week 8	1.7	1.7	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	0.0
Xanomeline Low Dose		Week 16	1.5	1.5	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 20	1.5	1.5	0.0
Xanomeline Low Dose		Week 24	1.5	1.5	0.0
Xanomeline Low Dose		Week 26	1.6	1.5	0.1
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Xanomeline Low Dose		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 12	1.6	1.6	0.0
Xanomeline Low Dose		Week 16	1.7	1.6	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 20	1.6	1.6	0.0
Xanomeline Low Dose		Week 24	1.6	1.6	0.0
Xanomeline Low Dose		Week 26	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	0.0
Xanomeline Low Dose		Week 6	1.6	1.6	0.0
Xanomeline Low Dose		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 12	1.6	1.6	0.0
Xanomeline High Dose		Week 16	1.6	1.6	0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 20	1.6	1.6	0.0
Xanomeline High Dose		Week 24	1.6	1.6	-0.0
Xanomeline High Dose		Week 26	1.6	1.6	0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	-0.0
Placebo		Week 12	1.6	1.6	-0.0
Placebo		Week 16	1.6	1.6	-0.0
Placebo		Week 2	1.6	1.6	0.0
Placebo		Week 20	1.5	1.6	-0.1
Placebo		Week 24	1.5	1.6	-0.1
Placebo		Week 26	1.5	1.6	-0.1
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.6	1.6	-0.0
Placebo		Week 8	1.6	1.6	-0.0
Xanomeline High Dose		Week 12	1.5	1.5	0.0
Xanomeline High Dose		Week 16	1.5	1.5	0.0
Xanomeline High Dose		Week 2	1.5	1.5	0.0
Xanomeline High Dose		Week 20	1.6	1.5	0.0
Xanomeline High Dose		Week 24	1.6	1.5	0.0
Xanomeline High Dose		Week 26	1.6	1.5	0.0
Xanomeline High Dose		Week 4	1.5	1.5	0.0
Xanomeline High Dose		Week 6	1.5	1.5	0.0
Xanomeline High Dose		Week 8	1.5	1.5	0.0
Placebo		Week 12	2.0	2.0	0.0
Placebo		Week 16	2.0	2.0	-0.0
Placebo		Week 2	2.0	2.0	-0.0
Placebo		Week 20	2.0	2.0	0.0
Placebo		Week 24	2.0	2.0	-0.0
Placebo		Week 26	2.0	2.0	0.0
Placebo		Week 4	2.0	2.0	-0.0
Placebo		Week 6	2.0	2.0	-0.0
Placebo		Week 8	2.0	2.0	0.0
Placebo		Week 12	2.1	2.0	0.1
Placebo		Week 16	2.1	2.0	0.1
Placebo		Week 2	2.0	2.0	0.0
Placebo		Week 20	2.0	2.0	0.1
Placebo		Week 24	2.1	2.0	0.1
Placebo		Week 26	2.0	2.0	0.0
Placebo		Week 4	2.0	2.0	0.0
Placebo		Week 6	2.0	2.0	0.0
Placebo		Week 8	2.0	2.0	0.0
Xanomeline Low Dose		Week 12	2.0	2.0	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 4	2.0	2.0	0.0
Xanomeline Low Dose		Week 6	2.0	2.0	0.0
Xanomeline Low Dose		Week 8	2.0	2.0	0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	0.0
Placebo		Week 4	1.5	1.5	0.0
Placebo		Week 6	1.5	1.5	0.0
Placebo		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 2	1.5	1.5	-0.0
Xanomeline Low Dose		Week 4	1.5	1.5	-0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Xanomeline Low Dose		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 12	2.0	2.0	-0.0
Xanomeline Low Dose		Week 16	2.0	2.0	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	-0.0
Xanomeline Low Dose		Week 20	2.0	2.0	0.0
Xanomeline Low Dose		Week 24	2.0	2.0	0.0
Xanomeline Low Dose		Week 26	2.0	2.0	-0.0
Xanomeline Low Dose		Week 4	2.0	2.0	0.0
Xanomeline Low Dose		Week 6	2.0	2.0	-0.0
Xanomeline Low Dose		Week 8	2.0	2.0	-0.0
Xanomeline High Dose		Week 12	1.5	1.5	0.0
Xanomeline High Dose		Week 16	1.5	1.5	0.0
Xanomeline High Dose		Week 2	1.5	1.5	0.0
Xanomeline High Dose		Week 20	1.5	1.5	0.0
Xanomeline High Dose		Week 24	1.5	1.5	0.0
Xanomeline High Dose		Week 26	1.5	1.5	0.0
Xanomeline High Dose		Week 4	1.5	1.5	0.0
Xanomeline High Dose		Week 6	1.5	1.5	0.0
Xanomeline High Dose		Week 8	1.5	1.5	0.0
Placebo		Week 12	1.6	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	-0.0
Placebo		Week 20	1.6	1.5	0.0
Placebo		Week 24	1.6	1.5	0.0
Placebo		Week 26	1.6	1.5	0.0
Placebo		Week 4	1.6	1.5	0.0
Placebo		Week 6	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	-0.0
Xanomeline Low Dose		Week 12	1.6	1.6	-0.0
Xanomeline Low Dose		Week 16	1.6	1.6	-0.0
Xanomeline Low Dose		Week 2	1.6	1.6	-0.0
Xanomeline Low Dose		Week 20	1.6	1.6	0.0
Xanomeline Low Dose		Week 24	1.6	1.6	-0.0
Xanomeline Low Dose		Week 26	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	-0.0
Xanomeline Low Dose		Week 6	1.6	1.6	-0.0
Xanomeline Low Dose		Week 8	1.6	1.6	-0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 4	1.8	1.8	-0.0
Xanomeline Low Dose		Week 6	1.8	1.8	-0.0
Xanomeline Low Dose		Week 8	1.9	1.8	0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	0.0
Placebo		Week 12	1.5	1.4	0.0
Placebo		Week 16	1.5	1.4	0.0
Placebo		Week 2	1.4	1.4	-0.0
Placebo		Week 20	1.5	1.4	0.0
Placebo		Week 24	1.5	1.4	0.0
Placebo		Week 4	1.4	1.4	-0.0
Placebo		Week 6	1.4	1.4	-0.0
Placebo		Week 8	1.5	1.4	0.0
Xanomeline High Dose		Week 2	1.9	1.9	-0.0
Xanomeline High Dose		Week 2	1.7	1.6	0.0
Xanomeline High Dose		Week 4	1.6	1.6	0.0
Xanomeline High Dose		Week 6	1.6	1.6	-0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Placebo		Week 12	1.7	1.7	0.1
Placebo		Week 16	1.7	1.7	0.1
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	0.0
Placebo		Week 24	1.7	1.7	0.0
Placebo		Week 4	1.7	1.7	0.0
Placebo		Week 6	1.7	1.7	0.0
Placebo		Week 8	1.7	1.7	0.1
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.6	1.5	0.0
Placebo		Week 4	1.5	1.5	0.0
Placebo		Week 6	1.5	1.5	0.0
Placebo		Week 8	1.5	1.5	0.0
Placebo		Week 12	1.8	1.9	-0.0
Placebo		Week 16	1.8	1.9	-0.0
Placebo		Week 2	1.9	1.9	0.0
Placebo		Week 20	1.9	1.9	0.0
Placebo		Week 24	1.9	1.9	0.0
Placebo		Week 26	1.9	1.9	0.0
Placebo		Week 4	1.9	1.9	0.0
Placebo		Week 6	1.9	1.9	0.0
Placebo		Week 8	1.9	1.9	0.0
Placebo		Week 12	2.0	2.0	-0.0
Placebo		Week 16	2.0	2.0	-0.0
Placebo		Week 2	2.0	2.0	-0.0
Placebo		Week 20	2.0	2.0	0.0
Placebo		Week 24	2.0	2.0	0.0
Placebo		Week 26	2.0	2.0	0.0
Placebo		Week 4	2.0	2.0	-0.0
Placebo		Week 6	2.0	2.0	-0.0
Placebo		Week 8	2.0	2.0	-0.0
Xanomeline Low Dose		Week 12	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	-0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	-0.0
Xanomeline High Dose		Week 8	1.8	1.8	-0.0
Xanomeline Low Dose		Week 2	1.9	1.9	-0.0
Xanomeline Low Dose		Week 4	1.9	1.9	0.0
Xanomeline Low Dose		Week 12	1.8	1.8	0.0
Xanomeline Low Dose		Week 16	1.8	1.8	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	0.0
Xanomeline Low Dose		Week 20	1.8	1.8	0.0
Xanomeline Low Dose		Week 24	1.8	1.8	0.0
Xanomeline Low Dose		Week 26	1.8	1.8	0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Placebo		Week 12	1.5	1.4	0.0
Placebo		Week 16	1.5	1.4	0.0
Placebo		Week 2	1.5	1.4	0.0
Placebo		Week 20	1.4	1.4	0.0
Placebo		Week 24	1.5	1.4	0.0
Placebo		Week 26	1.5	1.4	0.0
Placebo		Week 4	1.5	1.4	0.0
Placebo		Week 6	1.5	1.4	0.0
Placebo		Week 8	1.5	1.4	0.0
Xanomeline Low Dose		Week 12	1.4	1.4	-0.0
Xanomeline Low Dose		Week 2	1.4	1.4	-0.0
Xanomeline Low Dose		Week 4	1.4	1.4	-0.0
Xanomeline Low Dose		Week 6	1.4	1.4	-0.0
Xanomeline Low Dose		Week 8	1.4	1.4	-0.0
Xanomeline Low Dose		Week 12	1.6	1.6	0.0
Xanomeline Low Dose		Week 16	1.6	1.6	0.0
Xanomeline Low Dose		Week 2	1.6	1.6	-0.0
Xanomeline Low Dose		Week 20	1.6	1.6	0.0
Xanomeline Low Dose		Week 24	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	0.0
Xanomeline Low Dose		Week 6	1.6	1.6	0.0
Xanomeline Low Dose		Week 8	1.6	1.6	0.0
Placebo		Week 12	1.6	1.6	-0.0
Placebo		Week 16	1.6	1.6	-0.0
Placebo		Week 2	1.6	1.6	-0.0
Placebo		Week 20	1.6	1.6	-0.0
Placebo		Week 24	1.6	1.6	-0.0
Placebo		Week 26	1.6	1.6	-0.0
Placebo		Week 4	1.6	1.6	-0.0
Placebo		Week 6	1.6	1.6	-0.0
Placebo		Week 8	1.6	1.6	-0.0
Xanomeline Low Dose		Week 12	1.7	1.7	0.0
Xanomeline Low Dose		Week 16	1.6	1.7	-0.0
Xanomeline Low Dose		Week 2	1.7	1.7	0.0
Xanomeline Low Dose		Week 20	1.6	1.7	-0.0
Xanomeline Low Dose		Week 24	1.6	1.7	-0.0
Xanomeline Low Dose		Week 4	1.7	1.7	0.0
Xanomeline Low Dose		Week 6	1.7	1.7	0.0
Xanomeline Low Dose		Week 8	1.7	1.7	0.0
Placebo		Week 12	2.0	2.1	-0.0
Placebo		Week 16	2.0	2.1	-0.0
Placebo		Week 2	2.1	2.1	0.0
Placebo		Week 20	2.0	2.1	-0.0
Placebo		Week 24	2.1	2.1	-0.0
Placebo		Week 26	2.1	2.1	0.0
Placebo		Week 4	2.0	2.1	-0.0
Placebo		Week 6	2.0	2.1	-0.0
Placebo		Week 8	2.0	2.1	-0.0
Xanomeline High Dose		Week 12	1.8	1.8	-0.0
Xanomeline High Dose		Week 16	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	-0.0
Xanomeline High Dose		Week 6	1.8	1.8	-0.0
Xanomeline High Dose		Week 8	1.8	1.8	-0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline High Dose		Week 4	1.7	1.7	0.0
Xanomeline Low Dose		Week 2	1.8	1.8	-0.0
Xanomeline Low Dose		Week 4	1.8	1.8	0.0
Xanomeline Low Dose		Week 6	1.8	1.8	0.0
Xanomeline Low Dose		Week 8	1.8	1.8	0.0
Placebo		Week 2	1.6	1.6	-0.0
Placebo		Week 4	1.6	1.6	0.0
Placebo		Week 6	1.6	1.6	0.0
Xanomeline Low Dose		Week 12	1.9	2.0	-0.1
Xanomeline Low Dose		Week 16	1.9	2.0	-0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 4	2.0	2.0	-0.0
Xanomeline Low Dose		Week 6	1.9	2.0	-0.0
Xanomeline Low Dose		Week 8	1.9	2.0	-0.0
Xanomeline High Dose		Week 12	1.5	1.6	-0.0
Xanomeline High Dose		Week 16	1.5	1.6	-0.0
Xanomeline High Dose		Week 2	1.6	1.6	0.0
Xanomeline High Dose		Week 20	1.5	1.6	-0.0
Xanomeline High Dose		Week 24	1.5	1.6	-0.0
Xanomeline High Dose		Week 26	1.5	1.6	-0.0
Xanomeline High Dose		Week 4	1.6	1.6	-0.0
Xanomeline High Dose		Week 6	1.6	1.6	-0.0
Xanomeline High Dose		Week 8	1.6	1.6	0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline High Dose		Week 4	1.7	1.7	0.0
Xanomeline High Dose		Week 6	1.7	1.7	0.0
Xanomeline High Dose		Week 8	1.7	1.7	0.0
Xanomeline High Dose		Week 12	1.8	1.8	0.0
Xanomeline High Dose		Week 16	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 20	1.8	1.8	0.0
Xanomeline High Dose		Week 24	1.8	1.8	0.0
Xanomeline High Dose		Week 26	1.7	1.8	-0.1
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	0.0
Xanomeline High Dose		Week 8	1.8	1.8	0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	0.0
Placebo		Week 2	1.5	1.5	0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	0.0
Placebo		Week 26	1.5	1.5	-0.0
Placebo		Week 4	1.5	1.5	0.0
Placebo		Week 6	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	0.0
Xanomeline High Dose		Week 12	1.5	1.5	0.0
Xanomeline High Dose		Week 16	1.5	1.5	0.0
Xanomeline High Dose		Week 2	1.5	1.5	0.0
Xanomeline High Dose		Week 20	1.5	1.5	0.0
Xanomeline High Dose		Week 24	1.5	1.5	0.0
Xanomeline High Dose		Week 26	1.5	1.5	0.0
Xanomeline High Dose		Week 4	1.5	1.5	0.0
Xanomeline High Dose		Week 6	1.5	1.5	0.0
Xanomeline High Dose		Week 8	1.5	1.5	0.0
Xanomeline Low Dose		Week 12	1.5	1.5	0.0
Xanomeline Low Dose		Week 16	1.5	1.5	0.0
Xanomeline Low Dose		Week 2	1.4	1.5	-0.0
Xanomeline Low Dose		Week 20	1.5	1.5	0.0
Xanomeline Low Dose		Week 24	1.5	1.5	0.0
Xanomeline Low Dose		Week 26	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline Low Dose		Week 6	1.5	1.5	0.0
Xanomeline Low Dose		Week 8	1.5	1.5	0.0
Xanomeline High Dose		Week 12	2.0	1.5	0.5
Xanomeline High Dose		Week 16	2.0	1.5	0.5
Xanomeline High Dose		Week 2	2.0	1.5	0.5
Xanomeline High Dose		Week 20	2.0	1.5	0.5
Xanomeline High Dose		Week 24	2.0	1.5	0.5
Xanomeline High Dose		Week 26	2.0	1.5	0.5
Xanomeline High Dose		Week 4	2.0	1.5	0.5
Xanomeline High Dose		Week 6	2.0	1.5	0.5
Xanomeline High Dose		Week 8	2.0	1.5	0.5
Xanomeline High Dose		Week 12	1.8	1.8	0.0
Xanomeline High Dose		Week 16	1.8	1.8	0.0
Xanomeline High Dose		Week 2	1.8	1.8	0.0
Xanomeline High Dose		Week 20	1.8	1.8	0.0
Xanomeline High Dose		Week 24	1.8	1.8	0.0
Xanomeline High Dose		Week 26	1.8	1.8	0.0
Xanomeline High Dose		Week 4	1.8	1.8	0.0
Xanomeline High Dose		Week 6	1.8	1.8	-0.0
Xanomeline High Dose		Week 8	1.8	1.8	-0.0
Placebo		Week 2	1.8	1.7	0.0
Placebo		Week 4	1.8	1.7	0.0
Placebo		Week 6	1.8	1.7	0.0
Placebo		Week 8	1.7	1.7	0.0
Placebo		Week 2	1.6	1.6	0.0
Placebo		Week 4	1.6	1.6	-0.0
Placebo		Week 6	1.6	1.6	0.0
Placebo		Week 8	1.6	1.6	-0.0
Xanomeline High Dose		Week 12	2.0	2.0	0.0
Xanomeline High Dose		Week 16	2.1	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	-0.0
Xanomeline High Dose		Week 20	2.1	2.0	0.1
Xanomeline High Dose		Week 4	2.0	2.0	0.0
Xanomeline High Dose		Week 6	2.1	2.0	0.0
Xanomeline High Dose		Week 8	2.1	2.0	0.0
Xanomeline Low Dose		Week 12	1.4	1.4	-0.0
Xanomeline Low Dose		Week 16	1.4	1.4	-0.0
Xanomeline Low Dose		Week 2	1.4	1.4	0.0
Xanomeline Low Dose		Week 20	1.4	1.4	-0.0
Xanomeline Low Dose		Week 24	1.4	1.4	-0.0
Xanomeline Low Dose		Week 4	1.4	1.4	0.0
Xanomeline Low Dose		Week 6	1.4	1.4	0.0
Xanomeline Low Dose		Week 8	1.4	1.4	-0.0
Xanomeline Low Dose		Week 2	1.5	1.5	0.0
Xanomeline Low Dose		Week 4	1.5	1.5	0.0
Xanomeline High Dose		Week 12	2.1	2.0	0.0
Xanomeline High Dose		Week 16	2.1	2.0	0.0
Xanomeline High Dose		Week 2	2.0	2.0	0.0
Xanomeline High Dose		Week 20	2.0	2.0	0.0
Xanomeline High Dose		Week 4	2.1	2.0	0.0
Xanomeline High Dose		Week 6	2.1	2.0	0.0
Xanomeline High Dose		Week 8	2.1	2.0	0.0
Placebo		Week 12	1.8	1.8	-0.0
Placebo		Week 16	1.8	1.8	-0.0
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 20	1.8	1.8	0.0
Placebo		Week 24	1.8	1.8	-0.0
Placebo		Week 26	1.8	1.8	-0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	0.0
Placebo		Week 12	1.5	1.5	0.0
Placebo		Week 16	1.5	1.5	-0.0
Placebo		Week 20	1.5	1.5	0.0
Placebo		Week 24	1.5	1.5	-0.0
Placebo		Week 4	1.5	1.5	-0.0
Placebo		Week 8	1.5	1.5	-0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Placebo		Week 12	1.8	1.8	0.0
Placebo		Week 2	1.8	1.8	0.0
Placebo		Week 4	1.8	1.8	0.0
Placebo		Week 6	1.8	1.8	0.0
Placebo		Week 8	1.8	1.8	0.0
Xanomeline Low Dose		Week 12	1.6	1.6	-0.0
Xanomeline Low Dose		Week 16	1.6	1.6	-0.0
Xanomeline Low Dose		Week 2	1.6	1.6	0.0
Xanomeline Low Dose		Week 4	1.6	1.6	-0.0
Xanomeline Low Dose		Week 6	1.6	1.6	-0.0
Xanomeline Low Dose		Week 8	1.6	1.6	-0.0
Xanomeline Low Dose		Week 12	2.0	2.0	0.0
Xanomeline Low Dose		Week 16	2.0	2.0	0.0
Xanomeline Low Dose		Week 2	2.0	2.0	0.0
Xanomeline Low Dose		Week 20	2.0	2.0	-0.0
Xanomeline Low Dose		Week 24	2.0	2.0	0.0
Xanomeline Low Dose		Week 26	2.0	2.0	0.0
Xanomeline Low Dose		Week 4	2.0	2.0	0.0
Xanomeline Low Dose		Week 6	2.0	2.0	0.0
Xanomeline Low Dose		Week 8	2.0	2.0	0.0
Xanomeline High Dose		Week 2	1.8	1.7	0.0
Xanomeline High Dose		Week 4	1.8	1.7	0.0
Xanomeline High Dose		Week 6	1.7	1.7	0.0
Xanomeline High Dose		Week 8	1.7	1.7	0.0
Placebo		Week 12	1.7	1.7	0.0
Placebo		Week 16	1.7	1.7	0.0
Placebo		Week 2	1.7	1.7	0.0
Placebo		Week 20	1.7	1.7	0.1
Placebo		Week 24	1.7	1.7	0.1
Placebo		Week 26	1.7	1.7	0.1
Placebo		Week 4	1.7	1.7	0.0
Placebo		Week 6	1.7	1.7	0.0
Placebo		Week 8	1.7	1.7	0.0
Xanomeline High Dose		Week 2	1.7	1.7	0.0
Xanomeline High Dose		Week 4	1.7	1.7	0.0
Xanomeline High Dose		Week 6	1.7	1.7	-0.0
Xanomeline High Dose		Week 8	1.7	1.7	0.0
Xanomeline High Dose		Week 2	1.5	1.5	-0.0
Xanomeline High Dose		Week 4	1.5	1.5	-0.0
Xanomeline High Dose		Week 6	1.5	1.5	-0.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

DIABP

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	68.0	56.0	12.0
Placebo		Week 12	60.0	51.0	9.0
Placebo		Week 12	64.0	61.0	3.0
Placebo		Week 16	66.0	56.0	10.0
Placebo		Week 16	68.0	51.0	17.0
Placebo		Week 16	66.0	61.0	5.0
Placebo		Week 2	56.0	56.0	0.0
Placebo		Week 2	50.0	51.0	-1.0
Placebo		Week 2	54.0	61.0	-7.0
Placebo		Week 20	67.0	56.0	11.0
Placebo		Week 20	65.0	51.0	14.0
Placebo		Week 20	63.0	61.0	2.0
Placebo		Week 24	63.0	56.0	7.0
Placebo		Week 24	57.0	51.0	6.0
Placebo		Week 24	71.0	61.0	10.0
Placebo		Week 26	61.0	56.0	5.0
Placebo		Week 26	59.0	51.0	8.0
Placebo		Week 26	55.0	61.0	-6.0
Placebo		Week 4	64.0	56.0	8.0
Placebo		Week 4	55.0	51.0	4.0
Placebo		Week 4	53.0	61.0	-8.0
Placebo		Week 6	55.0	56.0	-1.0
Placebo		Week 6	63.0	51.0	12.0
Placebo		Week 6	60.0	61.0	-1.0
Placebo		Week 8	67.0	56.0	11.0
Placebo		Week 8	62.0	51.0	11.0
Placebo		Week 8	71.0	61.0	10.0
Placebo			67.0	56.0
Placebo			61.0	51.0
Placebo			65.0	61.0
Placebo			72.0	56.0
Placebo			61.0	51.0
Placebo			53.0	61.0
Placebo		Week 2	88.0	84.0	4.0
Placebo		Week 2	86.0	86.0	0.0
Placebo		Week 2	90.0	88.0	2.0
Placebo			82.0	84.0
Placebo			88.0	86.0
Placebo			89.0	88.0
Xanomeline High Dose		Week 12	74.0	85.0	-11.0
Xanomeline High Dose		Week 12	83.0	76.0	7.0
Xanomeline High Dose		Week 12	80.0	75.0	5.0
Xanomeline High Dose		Week 16	75.0	85.0	-10.0
Xanomeline High Dose		Week 16	76.0	76.0	0.0
Xanomeline High Dose		Week 16	78.0	75.0	3.0
Xanomeline High Dose		Week 2	78.0	85.0	-7.0
Xanomeline High Dose		Week 2	80.0	76.0	4.0
Xanomeline High Dose		Week 2	80.0	75.0	5.0
Xanomeline High Dose		Week 20	79.0	85.0	-6.0
Xanomeline High Dose		Week 20	76.0	76.0	0.0
Xanomeline High Dose		Week 20	77.0	75.0	2.0
Xanomeline High Dose		Week 24	73.0	85.0	-12.0
Xanomeline High Dose		Week 24	72.0	76.0	-4.0
Xanomeline High Dose		Week 24	77.0	75.0	2.0
Xanomeline High Dose		Week 26	70.0	85.0	-15.0
Xanomeline High Dose		Week 26	79.0	76.0	3.0
Xanomeline High Dose		Week 26	77.0	75.0	2.0
Xanomeline High Dose		Week 4	69.0	85.0	-16.0
Xanomeline High Dose		Week 4	72.0	76.0	-4.0
Xanomeline High Dose		Week 4	68.0	75.0	-7.0
Xanomeline High Dose		Week 6	69.0	85.0	-16.0
Xanomeline High Dose		Week 6	77.0	76.0	1.0
Xanomeline High Dose		Week 6	76.0	75.0	1.0
Xanomeline High Dose		Week 8	76.0	85.0	-9.0
Xanomeline High Dose		Week 8	81.0	76.0	5.0
Xanomeline High Dose		Week 8	84.0	75.0	9.0
Xanomeline High Dose			82.0	85.0
Xanomeline High Dose			82.0	76.0
Xanomeline High Dose			84.0	75.0
Xanomeline High Dose			76.0	85.0
Xanomeline High Dose			85.0	76.0
Xanomeline High Dose			81.0	75.0
Xanomeline Low Dose	01-701-1033		84.0	83.0
Xanomeline Low Dose			81.0	67.0
Xanomeline Low Dose			85.0	70.0
Xanomeline High Dose		Week 12	71.0	60.0	11.0
Xanomeline High Dose		Week 12	66.0	75.0	-9.0
Xanomeline High Dose		Week 12	63.0	82.0	-19.0
Xanomeline High Dose		Week 16	87.0	60.0	27.0
Xanomeline High Dose		Week 16	77.0	75.0	2.0
Xanomeline High Dose		Week 16	72.0	82.0	-10.0
Xanomeline High Dose		Week 2	81.0	60.0	21.0
Xanomeline High Dose		Week 2	101.0	75.0	26.0
Xanomeline High Dose		Week 2	84.0	82.0	2.0
Xanomeline High Dose		Week 20	78.0	60.0	18.0
Xanomeline High Dose		Week 20	77.0	75.0	2.0
Xanomeline High Dose		Week 20	72.0	82.0	-10.0
Xanomeline High Dose		Week 24	81.0	60.0	21.0
Xanomeline High Dose		Week 24	97.0	75.0	22.0
Xanomeline High Dose		Week 24	98.0	82.0	16.0
Xanomeline High Dose		Week 26	67.0	60.0	7.0
Xanomeline High Dose		Week 26	93.0	75.0	18.0
Xanomeline High Dose		Week 26	66.0	82.0	-16.0
Xanomeline High Dose		Week 4	71.0	60.0	11.0
Xanomeline High Dose		Week 4	69.0	75.0	-6.0
Xanomeline High Dose		Week 4	71.0	82.0	-11.0
Xanomeline High Dose		Week 6	57.0	60.0	-3.0
Xanomeline High Dose		Week 6	76.0	75.0	1.0
Xanomeline High Dose		Week 6	80.0	82.0	-2.0
Xanomeline High Dose		Week 8	73.0	60.0	13.0
Xanomeline High Dose		Week 8	80.0	75.0	5.0
Xanomeline High Dose		Week 8	76.0	82.0	-6.0
Xanomeline High Dose			54.0	60.0
Xanomeline High Dose			65.0	75.0
Xanomeline High Dose			61.0	82.0
Placebo		Week 2	72.0	61.0	11.0
Placebo		Week 2	84.0	68.0	16.0
Placebo		Week 2	73.0	78.0	-5.0
Placebo			72.0	61.0
Placebo			56.0	68.0
Placebo			73.0	78.0
Xanomeline Low Dose		Week 12	74.0	72.0	2.0
Xanomeline Low Dose		Week 12	70.0	78.0	-8.0
Xanomeline Low Dose		Week 12	72.0	80.0	-8.0
Xanomeline Low Dose		Week 16	70.0	72.0	-2.0
Xanomeline Low Dose		Week 16	76.0	78.0	-2.0
Xanomeline Low Dose		Week 16	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	82.0	78.0	4.0
Xanomeline Low Dose		Week 2	84.0	80.0	4.0
Xanomeline Low Dose		Week 20	67.0	72.0	-5.0
Xanomeline Low Dose		Week 20	58.0	78.0	-20.0
Xanomeline Low Dose		Week 20	61.0	80.0	-19.0
Xanomeline Low Dose		Week 24	83.0	72.0	11.0
Xanomeline Low Dose		Week 24	84.0	78.0	6.0
Xanomeline Low Dose		Week 24	84.0	80.0	4.0
Xanomeline Low Dose		Week 26	72.0	72.0	0.0
Xanomeline Low Dose		Week 26	78.0	78.0	0.0
Xanomeline Low Dose		Week 26	77.0	80.0	-3.0
Xanomeline Low Dose		Week 4	71.0	72.0	-1.0
Xanomeline Low Dose		Week 4	70.0	78.0	-8.0
Xanomeline Low Dose		Week 4	68.0	80.0	-12.0
Xanomeline Low Dose		Week 6	68.0	72.0	-4.0
Xanomeline Low Dose		Week 6	70.0	78.0	-8.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 8	75.0	72.0	3.0
Xanomeline Low Dose		Week 8	73.0	78.0	-5.0
Xanomeline Low Dose		Week 8	66.0	80.0	-14.0
Xanomeline Low Dose			67.0	72.0
Xanomeline Low Dose			79.0	78.0
Xanomeline Low Dose			67.0	80.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose		Week 2	79.0	83.0	-4.0
Xanomeline Low Dose		Week 2	68.0	67.0	1.0
Xanomeline Low Dose		Week 2	69.0	69.0	0.0
Xanomeline Low Dose		Week 4	68.0	83.0	-15.0
Xanomeline Low Dose		Week 4	53.0	67.0	-14.0
Xanomeline Low Dose		Week 4	56.0	69.0	-13.0
Xanomeline Low Dose		Week 6	77.0	83.0	-6.0
Xanomeline Low Dose		Week 6	71.0	67.0	4.0
Xanomeline Low Dose		Week 6	69.0	69.0	0.0
Xanomeline Low Dose		Week 8	76.0	83.0	-7.0
Xanomeline Low Dose		Week 8	52.0	67.0	-15.0
Xanomeline Low Dose		Week 8	60.0	69.0	-9.0
Xanomeline Low Dose			78.0	83.0
Xanomeline Low Dose			70.0	67.0
Xanomeline Low Dose			72.0	69.0
Xanomeline Low Dose			69.0	83.0
Xanomeline Low Dose			61.0	67.0
Xanomeline Low Dose			50.0	69.0
Placebo		Week 12	72.0	84.0	-12.0
Placebo		Week 12	68.0	79.0	-11.0
Placebo		Week 12	72.0	84.0	-12.0
Placebo		Week 16	72.0	84.0	-12.0
Placebo		Week 16	68.0	79.0	-11.0
Placebo		Week 16	68.0	84.0	-16.0
Placebo		Week 2	82.0	84.0	-2.0
Placebo		Week 2	69.0	79.0	-10.0
Placebo		Week 2	73.0	84.0	-11.0
Placebo		Week 20	82.0	84.0	-2.0
Placebo		Week 20	85.0	79.0	6.0
Placebo		Week 20	89.0	84.0	5.0
Placebo		Week 24	76.0	84.0	-8.0
Placebo		Week 24	72.0	79.0	-7.0
Placebo		Week 24	73.0	84.0	-11.0
Placebo		Week 26	74.0	84.0	-10.0
Placebo		Week 26	67.0	79.0	-12.0
Placebo		Week 26	72.0	84.0	-12.0
Placebo		Week 4	75.0	84.0	-9.0
Placebo		Week 4	68.0	79.0	-11.0
Placebo		Week 4	80.0	84.0	-4.0
Placebo		Week 6	62.0	84.0	-22.0
Placebo		Week 6	68.0	79.0	-11.0
Placebo		Week 6	68.0	84.0	-16.0
Placebo		Week 8	67.0	84.0	-17.0
Placebo		Week 8	72.0	79.0	-7.0
Placebo		Week 8	73.0	84.0	-11.0
Placebo			76.0	84.0
Placebo			79.0	79.0
Placebo			85.0	84.0
Placebo			75.0	84.0
Placebo			72.0	79.0
Placebo			79.0	84.0
Placebo		Week 12	67.0	74.0	-7.0
Placebo		Week 12	60.0	67.0	-7.0
Placebo		Week 12	72.0	68.0	4.0
Placebo		Week 16	76.0	74.0	2.0
Placebo		Week 16	73.0	67.0	6.0
Placebo		Week 16	76.0	68.0	8.0
Placebo		Week 2	72.0	74.0	-2.0
Placebo		Week 2	69.0	67.0	2.0
Placebo		Week 2	65.0	68.0	-3.0
Placebo		Week 20	63.0	74.0	-11.0
Placebo		Week 20	64.0	67.0	-3.0
Placebo		Week 20	56.0	68.0	-12.0
Placebo		Week 24	76.0	74.0	2.0
Placebo		Week 24	76.0	67.0	9.0
Placebo		Week 24	80.0	68.0	12.0
Placebo		Week 26	70.0	74.0	-4.0
Placebo		Week 26	91.0	67.0	24.0
Placebo		Week 26	84.0	68.0	16.0
Placebo		Week 4	74.0	74.0	0.0
Placebo		Week 4	80.0	67.0	13.0
Placebo		Week 4	72.0	68.0	4.0
Placebo		Week 6	64.0	74.0	-10.0
Placebo		Week 6	70.0	67.0	3.0
Placebo		Week 6	71.0	68.0	3.0
Placebo		Week 8	75.0	74.0	1.0
Placebo		Week 8	68.0	67.0	1.0
Placebo		Week 8	76.0	68.0	8.0
Placebo			75.0	74.0
Placebo			72.0	67.0
Placebo			73.0	68.0
Placebo			68.0	74.0
Placebo			68.0	67.0
Placebo			75.0	68.0
Xanomeline High Dose		Week 12	56.0	59.0	-3.0
Xanomeline High Dose		Week 12	60.0	56.0	4.0
Xanomeline High Dose		Week 12	60.0	54.0	6.0
Xanomeline High Dose		Week 16	56.0	59.0	-3.0
Xanomeline High Dose		Week 16	60.0	56.0	4.0
Xanomeline High Dose		Week 16	79.0	54.0	25.0
Xanomeline High Dose		Week 2	56.0	59.0	-3.0
Xanomeline High Dose		Week 2	59.0	56.0	3.0
Xanomeline High Dose		Week 2	64.0	54.0	10.0
Xanomeline High Dose		Week 20	77.0	59.0	18.0
Xanomeline High Dose		Week 20	58.0	56.0	2.0
Xanomeline High Dose		Week 20	64.0	54.0	10.0
Xanomeline High Dose		Week 24	73.0	59.0	14.0
Xanomeline High Dose		Week 24	64.0	56.0	8.0
Xanomeline High Dose		Week 24	60.0	54.0	6.0
Xanomeline High Dose		Week 4	69.0	59.0	10.0
Xanomeline High Dose		Week 4	73.0	56.0	17.0
Xanomeline High Dose		Week 4	58.0	54.0	4.0
Xanomeline High Dose		Week 6	55.0	59.0	-4.0
Xanomeline High Dose		Week 6	55.0	56.0	-1.0
Xanomeline High Dose		Week 6	55.0	54.0	1.0
Xanomeline High Dose		Week 8	59.0	59.0	0.0
Xanomeline High Dose		Week 8	56.0	56.0	0.0
Xanomeline High Dose		Week 8	56.0	54.0	2.0
Xanomeline High Dose			56.0	59.0
Xanomeline High Dose			62.0	56.0
Xanomeline High Dose			60.0	54.0
Xanomeline High Dose			64.0	59.0
Xanomeline High Dose			56.0	56.0
Xanomeline High Dose			60.0	54.0
Xanomeline High Dose		Week 2	57.0	51.0	6.0
Xanomeline High Dose		Week 2	43.0	57.0	-14.0
Xanomeline High Dose		Week 2	58.0	51.0	7.0
Xanomeline High Dose		Week 4	55.0	51.0	4.0
Xanomeline High Dose		Week 4	59.0	57.0	2.0
Xanomeline High Dose		Week 4	56.0	51.0	5.0
Xanomeline High Dose			51.0	51.0
Xanomeline High Dose			52.0	57.0
Xanomeline High Dose			62.0	51.0
Xanomeline High Dose			45.0	51.0
Xanomeline High Dose			60.0	57.0
Xanomeline High Dose			56.0	51.0
Xanomeline High Dose		Week 12	68.0	70.0	-2.0
Xanomeline High Dose		Week 12	69.0	58.0	11.0
Xanomeline High Dose		Week 12	69.0	76.0	-7.0
Xanomeline High Dose		Week 16	68.0	70.0	-2.0
Xanomeline High Dose		Week 16	73.0	58.0	15.0
Xanomeline High Dose		Week 16	76.0	76.0	0.0
Xanomeline High Dose		Week 2	69.0	70.0	-1.0
Xanomeline High Dose		Week 2	66.0	58.0	8.0
Xanomeline High Dose		Week 2	73.0	76.0	-3.0
Xanomeline High Dose		Week 20	69.0	70.0	-1.0
Xanomeline High Dose		Week 20	63.0	58.0	5.0
Xanomeline High Dose		Week 20	69.0	76.0	-7.0
Xanomeline High Dose		Week 24	64.0	70.0	-6.0
Xanomeline High Dose		Week 24	73.0	58.0	15.0
Xanomeline High Dose		Week 24	73.0	76.0	-3.0
Xanomeline High Dose		Week 26	68.0	70.0	-2.0
Xanomeline High Dose		Week 26	73.0	58.0	15.0
Xanomeline High Dose		Week 26	68.0	76.0	-8.0
Xanomeline High Dose		Week 4	69.0	70.0	-1.0
Xanomeline High Dose		Week 4	65.0	58.0	7.0
Xanomeline High Dose		Week 4	61.0	76.0	-15.0
Xanomeline High Dose		Week 6	76.0	70.0	6.0
Xanomeline High Dose		Week 6	60.0	58.0	2.0
Xanomeline High Dose		Week 6	70.0	76.0	-6.0
Xanomeline High Dose		Week 8	75.0	70.0	5.0
Xanomeline High Dose		Week 8	75.0	58.0	17.0
Xanomeline High Dose		Week 8	77.0	76.0	1.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			73.0	58.0
Xanomeline High Dose			67.0	76.0
Xanomeline High Dose			76.0	70.0
Xanomeline High Dose			77.0	58.0
Xanomeline High Dose			79.0	76.0
Placebo		Week 12	63.0	60.0	3.0
Placebo		Week 12	66.0	62.0	4.0
Placebo		Week 12	60.0	60.0	0.0
Placebo		Week 16	62.0	60.0	2.0
Placebo		Week 16	56.0	62.0	-6.0
Placebo		Week 16	56.0	60.0	-4.0
Placebo		Week 2	63.0	60.0	3.0
Placebo		Week 2	52.0	62.0	-10.0
Placebo		Week 2	67.0	60.0	7.0
Placebo		Week 20	54.0	60.0	-6.0
Placebo		Week 20	57.0	62.0	-5.0
Placebo		Week 20	61.0	60.0	1.0
Placebo		Week 24	55.0	60.0	-5.0
Placebo		Week 24	52.0	62.0	-10.0
Placebo		Week 24	58.0	60.0	-2.0
Placebo		Week 4	56.0	60.0	-4.0
Placebo		Week 4	52.0	62.0	-10.0
Placebo		Week 4	61.0	60.0	1.0
Placebo		Week 6	59.0	60.0	-1.0
Placebo		Week 6	68.0	62.0	6.0
Placebo		Week 6	72.0	60.0	12.0
Placebo		Week 8	56.0	60.0	-4.0
Placebo		Week 8	66.0	62.0	4.0
Placebo		Week 8	60.0	60.0	0.0
Placebo			72.0	60.0
Placebo			68.0	62.0
Placebo			74.0	60.0
Placebo			57.0	60.0
Placebo			52.0	62.0
Placebo			54.0	60.0
Xanomeline High Dose		Week 2	87.0	76.0	11.0
Xanomeline High Dose		Week 2	93.0	80.0	13.0
Xanomeline High Dose		Week 2	97.0	84.0	13.0
Xanomeline High Dose		Week 4	79.0	76.0	3.0
Xanomeline High Dose		Week 4	83.0	80.0	3.0
Xanomeline High Dose		Week 4	83.0	84.0	-1.0
Xanomeline High Dose			91.0	76.0
Xanomeline High Dose			96.0	80.0
Xanomeline High Dose			99.0	84.0
Xanomeline High Dose			86.0	76.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			84.0	84.0
Xanomeline Low Dose		Week 2	87.0	78.0	9.0
Xanomeline Low Dose		Week 2	73.0	66.0	7.0
Xanomeline Low Dose		Week 2	77.0	68.0	9.0
Xanomeline Low Dose		Week 4	80.0	78.0	2.0
Xanomeline Low Dose		Week 4	78.0	66.0	12.0
Xanomeline Low Dose		Week 4	77.0	68.0	9.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			73.0	66.0
Xanomeline Low Dose			73.0	68.0
Xanomeline Low Dose			83.0	78.0
Xanomeline Low Dose			77.0	66.0
Xanomeline Low Dose			79.0	68.0
Xanomeline Low Dose		Week 12	63.0	84.0	-21.0
Xanomeline Low Dose		Week 12	64.0	78.0	-14.0
Xanomeline Low Dose		Week 12	68.0	82.0	-14.0
Xanomeline Low Dose		Week 16	77.0	84.0	-7.0
Xanomeline Low Dose		Week 16	70.0	78.0	-8.0
Xanomeline Low Dose		Week 16	80.0	82.0	-2.0
Xanomeline Low Dose		Week 2	72.0	84.0	-12.0
Xanomeline Low Dose		Week 2	72.0	78.0	-6.0
Xanomeline Low Dose		Week 2	76.0	82.0	-6.0
Xanomeline Low Dose		Week 20	60.0	84.0	-24.0
Xanomeline Low Dose		Week 20	82.0	78.0	4.0
Xanomeline Low Dose		Week 20	86.0	82.0	4.0
Xanomeline Low Dose		Week 24	85.0	84.0	1.0
Xanomeline Low Dose		Week 24	80.0	78.0	2.0
Xanomeline Low Dose		Week 24	88.0	82.0	6.0
Xanomeline Low Dose		Week 26	83.0	84.0	-1.0
Xanomeline Low Dose		Week 26	88.0	78.0	10.0
Xanomeline Low Dose		Week 26	82.0	82.0	0.0
Xanomeline Low Dose		Week 4	79.0	84.0	-5.0
Xanomeline Low Dose		Week 4	64.0	78.0	-14.0
Xanomeline Low Dose		Week 4	78.0	82.0	-4.0
Xanomeline Low Dose		Week 6	70.0	84.0	-14.0
Xanomeline Low Dose		Week 6	72.0	78.0	-6.0
Xanomeline Low Dose		Week 6	70.0	82.0	-12.0
Xanomeline Low Dose		Week 8	64.0	84.0	-20.0
Xanomeline Low Dose		Week 8	56.0	78.0	-22.0
Xanomeline Low Dose		Week 8	64.0	82.0	-18.0
Xanomeline Low Dose			86.0	84.0
Xanomeline Low Dose			84.0	78.0
Xanomeline Low Dose			80.0	82.0
Xanomeline Low Dose			70.0	84.0
Xanomeline Low Dose			82.0	78.0
Xanomeline Low Dose			77.0	82.0
Placebo		Week 12	50.0	40.0	10.0
Placebo		Week 12	50.0	56.0	-6.0
Placebo		Week 12	60.0	46.0	14.0
Placebo		Week 16	64.0	40.0	24.0
Placebo		Week 16	49.0	56.0	-7.0
Placebo		Week 16	49.0	46.0	3.0
Placebo		Week 2	48.0	40.0	8.0
Placebo		Week 2	61.0	56.0	5.0
Placebo		Week 2	54.0	46.0	8.0
Placebo		Week 20	56.0	40.0	16.0
Placebo		Week 20	53.0	56.0	-3.0
Placebo		Week 20	52.0	46.0	6.0
Placebo		Week 24	44.0	40.0	4.0
Placebo		Week 24	45.0	56.0	-11.0
Placebo		Week 24	56.0	46.0	10.0
Placebo		Week 26	51.0	40.0	11.0
Placebo		Week 26	39.0	56.0	-17.0
Placebo		Week 26	49.0	46.0	3.0
Placebo		Week 4	41.0	40.0	1.0
Placebo		Week 4	49.0	56.0	-7.0
Placebo		Week 4	46.0	46.0	0.0
Placebo		Week 6	61.0	40.0	21.0
Placebo		Week 6	62.0	56.0	6.0
Placebo		Week 6	57.0	46.0	11.0
Placebo		Week 8	57.0	40.0	17.0
Placebo		Week 8	53.0	56.0	-3.0
Placebo		Week 8	60.0	46.0	14.0
Placebo			41.0	40.0
Placebo			49.0	56.0
Placebo			49.0	46.0
Xanomeline Low Dose		Week 2	58.0	64.0	-6.0
Xanomeline Low Dose		Week 2	59.0	58.0	1.0
Xanomeline Low Dose		Week 2	64.0	50.0	14.0
Xanomeline Low Dose		Week 4	55.0	64.0	-9.0
Xanomeline Low Dose		Week 4	57.0	58.0	-1.0
Xanomeline Low Dose		Week 4	56.0	50.0	6.0
Xanomeline Low Dose		Week 6	60.0	64.0	-4.0
Xanomeline Low Dose		Week 6	68.0	58.0	10.0
Xanomeline Low Dose		Week 6	57.0	50.0	7.0
Xanomeline Low Dose		Week 8	59.0	64.0	-5.0
Xanomeline Low Dose		Week 8	65.0	58.0	7.0
Xanomeline Low Dose		Week 8	68.0	50.0	18.0
Xanomeline Low Dose			71.0	64.0
Xanomeline Low Dose			64.0	58.0
Xanomeline Low Dose			80.0	50.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			40.0	58.0
Xanomeline Low Dose			62.0	50.0
Placebo		Week 12	79.0	76.0	3.0
Placebo		Week 12	88.0	81.0	7.0
Placebo		Week 12	91.0	81.0	10.0
Placebo		Week 16	80.0	76.0	4.0
Placebo		Week 16	85.0	81.0	4.0
Placebo		Week 16	98.0	81.0	17.0
Placebo		Week 2	83.0	76.0	7.0
Placebo		Week 2	85.0	81.0	4.0
Placebo		Week 2	86.0	81.0	5.0
Placebo		Week 20	74.0	76.0	-2.0
Placebo		Week 20	66.0	81.0	-15.0
Placebo		Week 20	71.0	81.0	-10.0
Placebo		Week 24	72.0	76.0	-4.0
Placebo		Week 24	72.0	81.0	-9.0
Placebo		Week 24	72.0	81.0	-9.0
Placebo		Week 26	93.0	76.0	17.0
Placebo		Week 26	95.0	81.0	14.0
Placebo		Week 26	92.0	81.0	11.0
Placebo		Week 4	81.0	76.0	5.0
Placebo		Week 4	84.0	81.0	3.0
Placebo		Week 4	86.0	81.0	5.0
Placebo		Week 6	76.0	76.0	0.0
Placebo		Week 6	81.0	81.0	0.0
Placebo		Week 6	84.0	81.0	3.0
Placebo		Week 8	75.0	76.0	-1.0
Placebo		Week 8	79.0	81.0	-2.0
Placebo		Week 8	86.0	81.0	5.0
Placebo			88.0	76.0
Placebo			87.0	81.0
Placebo			91.0	81.0
Placebo			78.0	76.0
Placebo			77.0	81.0
Placebo			82.0	81.0
Xanomeline High Dose		Week 12	83.0	87.0	-4.0
Xanomeline High Dose		Week 12	85.0	85.0	0.0
Xanomeline High Dose		Week 12	87.0	86.0	1.0
Xanomeline High Dose		Week 16	85.0	87.0	-2.0
Xanomeline High Dose		Week 16	78.0	85.0	-7.0
Xanomeline High Dose		Week 16	85.0	86.0	-1.0
Xanomeline High Dose		Week 2	82.0	87.0	-5.0
Xanomeline High Dose		Week 2	78.0	85.0	-7.0
Xanomeline High Dose		Week 2	86.0	86.0	0.0
Xanomeline High Dose		Week 20	84.0	87.0	-3.0
Xanomeline High Dose		Week 20	90.0	85.0	5.0
Xanomeline High Dose		Week 20	77.0	86.0	-9.0
Xanomeline High Dose		Week 24	88.0	87.0	1.0
Xanomeline High Dose		Week 24	77.0	85.0	-8.0
Xanomeline High Dose		Week 24	81.0	86.0	-5.0
Xanomeline High Dose		Week 4	86.0	87.0	-1.0
Xanomeline High Dose		Week 4	85.0	85.0	0.0
Xanomeline High Dose		Week 4	85.0	86.0	-1.0
Xanomeline High Dose		Week 6	84.0	87.0	-3.0
Xanomeline High Dose		Week 6	82.0	85.0	-3.0
Xanomeline High Dose		Week 6	72.0	86.0	-14.0
Xanomeline High Dose		Week 8	85.0	87.0	-2.0
Xanomeline High Dose		Week 8	80.0	85.0	-5.0
Xanomeline High Dose		Week 8	85.0	86.0	-1.0
Xanomeline High Dose			92.0	87.0
Xanomeline High Dose			84.0	85.0
Xanomeline High Dose			89.0	86.0
Xanomeline High Dose			90.0	87.0
Xanomeline High Dose			90.0	85.0
Xanomeline High Dose			84.0	86.0
Xanomeline High Dose		Week 12	68.0	84.0	-16.0
Xanomeline High Dose		Week 12	77.0	88.0	-11.0
Xanomeline High Dose		Week 12	81.0	88.0	-7.0
Xanomeline High Dose		Week 2	66.0	84.0	-18.0
Xanomeline High Dose		Week 2	77.0	88.0	-11.0
Xanomeline High Dose		Week 2	80.0	88.0	-8.0
Xanomeline High Dose		Week 4	83.0	84.0	-1.0
Xanomeline High Dose		Week 4	80.0	88.0	-8.0
Xanomeline High Dose		Week 4	84.0	88.0	-4.0
Xanomeline High Dose		Week 6	72.0	84.0	-12.0
Xanomeline High Dose		Week 6	68.0	88.0	-20.0
Xanomeline High Dose		Week 6	75.0	88.0	-13.0
Xanomeline High Dose		Week 8	77.0	84.0	-7.0
Xanomeline High Dose		Week 8	85.0	88.0	-3.0
Xanomeline High Dose		Week 8	87.0	88.0	-1.0
Xanomeline High Dose			74.0	84.0
Xanomeline High Dose			64.0	88.0
Xanomeline High Dose			81.0	88.0
Xanomeline High Dose			82.0	84.0
Xanomeline High Dose			80.0	88.0
Xanomeline High Dose			84.0	88.0
Xanomeline High Dose		Week 12	68.0	72.0	-4.0
Xanomeline High Dose		Week 12	76.0	77.0	-1.0
Xanomeline High Dose		Week 12	70.0	70.0	0.0
Xanomeline High Dose		Week 16	82.0	72.0	10.0
Xanomeline High Dose		Week 16	75.0	77.0	-2.0
Xanomeline High Dose		Week 16	80.0	70.0	10.0
Xanomeline High Dose		Week 2	74.0	72.0	2.0
Xanomeline High Dose		Week 2	62.0	77.0	-15.0
Xanomeline High Dose		Week 2	72.0	70.0	2.0
Xanomeline High Dose		Week 20	72.0	72.0	0.0
Xanomeline High Dose		Week 20	75.0	77.0	-2.0
Xanomeline High Dose		Week 20	78.0	70.0	8.0
Xanomeline High Dose		Week 24	75.0	72.0	3.0
Xanomeline High Dose		Week 24	76.0	77.0	-1.0
Xanomeline High Dose		Week 24	80.0	70.0	10.0
Xanomeline High Dose		Week 26	62.0	72.0	-10.0
Xanomeline High Dose		Week 26	74.0	77.0	-3.0
Xanomeline High Dose		Week 26	79.0	70.0	9.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 4	75.0	77.0	-2.0
Xanomeline High Dose		Week 4	67.0	70.0	-3.0
Xanomeline High Dose		Week 6	79.0	72.0	7.0
Xanomeline High Dose		Week 6	78.0	77.0	1.0
Xanomeline High Dose		Week 6	80.0	70.0	10.0
Xanomeline High Dose		Week 8	67.0	72.0	-5.0
Xanomeline High Dose		Week 8	64.0	77.0	-13.0
Xanomeline High Dose		Week 8	73.0	70.0	3.0
Xanomeline High Dose			73.0	72.0
Xanomeline High Dose			83.0	77.0
Xanomeline High Dose			72.0	70.0
Xanomeline Low Dose		Week 12	84.0	83.0	1.0
Xanomeline Low Dose		Week 12	76.0	76.0	0.0
Xanomeline Low Dose		Week 12	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	84.0	83.0	1.0
Xanomeline Low Dose		Week 2	92.0	76.0	16.0
Xanomeline Low Dose		Week 2	84.0	80.0	4.0
Xanomeline Low Dose		Week 4	84.0	83.0	1.0
Xanomeline Low Dose		Week 4	87.0	76.0	11.0
Xanomeline Low Dose		Week 4	84.0	80.0	4.0
Xanomeline Low Dose		Week 6	83.0	83.0	0.0
Xanomeline Low Dose		Week 6	76.0	76.0	0.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	75.0	83.0	-8.0
Xanomeline Low Dose		Week 8	77.0	76.0	1.0
Xanomeline Low Dose		Week 8	77.0	80.0	-3.0
Xanomeline Low Dose			83.0	83.0
Xanomeline Low Dose			84.0	76.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			79.0	83.0
Xanomeline Low Dose			84.0	76.0
Xanomeline Low Dose			85.0	80.0
Xanomeline High Dose		Week 12	76.0	76.0	0.0
Xanomeline High Dose		Week 12	81.0	87.0	-6.0
Xanomeline High Dose		Week 12	81.0	83.0	-2.0
Xanomeline High Dose		Week 2	71.0	76.0	-5.0
Xanomeline High Dose		Week 2	79.0	87.0	-8.0
Xanomeline High Dose		Week 2	84.0	83.0	1.0
Xanomeline High Dose		Week 4	76.0	76.0	0.0
Xanomeline High Dose		Week 4	80.0	87.0	-7.0
Xanomeline High Dose		Week 4	80.0	83.0	-3.0
Xanomeline High Dose		Week 6	65.0	76.0	-11.0
Xanomeline High Dose		Week 6	70.0	87.0	-17.0
Xanomeline High Dose		Week 6	76.0	83.0	-7.0
Xanomeline High Dose		Week 8	77.0	76.0	1.0
Xanomeline High Dose		Week 8	84.0	87.0	-3.0
Xanomeline High Dose		Week 8	91.0	83.0	8.0
Xanomeline High Dose			73.0	76.0
Xanomeline High Dose			84.0	87.0
Xanomeline High Dose			84.0	83.0
Xanomeline High Dose			81.0	76.0
Xanomeline High Dose			71.0	87.0
Xanomeline High Dose			73.0	83.0
Xanomeline Low Dose		Week 12	75.0	71.0	4.0
Xanomeline Low Dose		Week 12	69.0	68.0	1.0
Xanomeline Low Dose		Week 12	68.0	68.0	0.0
Xanomeline Low Dose		Week 16	75.0	71.0	4.0
Xanomeline Low Dose		Week 16	76.0	68.0	8.0
Xanomeline Low Dose		Week 16	76.0	68.0	8.0
Xanomeline Low Dose		Week 2	81.0	71.0	10.0
Xanomeline Low Dose		Week 2	77.0	68.0	9.0
Xanomeline Low Dose		Week 2	79.0	68.0	11.0
Xanomeline Low Dose		Week 20	75.0	71.0	4.0
Xanomeline Low Dose		Week 20	69.0	68.0	1.0
Xanomeline Low Dose		Week 20	69.0	68.0	1.0
Xanomeline Low Dose		Week 24	75.0	71.0	4.0
Xanomeline Low Dose		Week 24	76.0	68.0	8.0
Xanomeline Low Dose		Week 24	76.0	68.0	8.0
Xanomeline Low Dose		Week 26	72.0	71.0	1.0
Xanomeline Low Dose		Week 26	65.0	68.0	-3.0
Xanomeline Low Dose		Week 26	68.0	68.0	0.0
Xanomeline Low Dose		Week 4	69.0	71.0	-2.0
Xanomeline Low Dose		Week 4	69.0	68.0	1.0
Xanomeline Low Dose		Week 4	61.0	68.0	-7.0
Xanomeline Low Dose		Week 6	75.0	71.0	4.0
Xanomeline Low Dose		Week 6	76.0	68.0	8.0
Xanomeline Low Dose		Week 6	71.0	68.0	3.0
Xanomeline Low Dose		Week 8	76.0	71.0	5.0
Xanomeline Low Dose		Week 8	64.0	68.0	-4.0
Xanomeline Low Dose		Week 8	62.0	68.0	-6.0
Xanomeline Low Dose			83.0	71.0
Xanomeline Low Dose			76.0	68.0
Xanomeline Low Dose			77.0	68.0
Xanomeline Low Dose			76.0	71.0
Xanomeline Low Dose			69.0	68.0
Xanomeline Low Dose			69.0	68.0
Xanomeline Low Dose		Week 12	57.0	70.0	-13.0
Xanomeline Low Dose		Week 12	59.0	66.0	-7.0
Xanomeline Low Dose		Week 12	63.0	68.0	-5.0
Xanomeline Low Dose		Week 16	62.0	70.0	-8.0
Xanomeline Low Dose		Week 16	60.0	66.0	-6.0
Xanomeline Low Dose		Week 16	64.0	68.0	-4.0
Xanomeline Low Dose		Week 2	61.0	70.0	-9.0
Xanomeline Low Dose		Week 2	66.0	66.0	0.0
Xanomeline Low Dose		Week 2	61.0	68.0	-7.0
Xanomeline Low Dose		Week 20	59.0	70.0	-11.0
Xanomeline Low Dose		Week 20	52.0	66.0	-14.0
Xanomeline Low Dose		Week 20	56.0	68.0	-12.0
Xanomeline Low Dose		Week 24	61.0	70.0	-9.0
Xanomeline Low Dose		Week 24	61.0	66.0	-5.0
Xanomeline Low Dose		Week 24	57.0	68.0	-11.0
Xanomeline Low Dose		Week 26	56.0	70.0	-14.0
Xanomeline Low Dose		Week 26	59.0	66.0	-7.0
Xanomeline Low Dose		Week 26	57.0	68.0	-11.0
Xanomeline Low Dose		Week 4	64.0	70.0	-6.0
Xanomeline Low Dose		Week 4	68.0	66.0	2.0
Xanomeline Low Dose		Week 4	62.0	68.0	-6.0
Xanomeline Low Dose		Week 6	70.0	70.0	0.0
Xanomeline Low Dose		Week 6	66.0	66.0	0.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Xanomeline Low Dose		Week 8	56.0	70.0	-14.0
Xanomeline Low Dose		Week 8	60.0	66.0	-6.0
Xanomeline Low Dose		Week 8	62.0	68.0	-6.0
Xanomeline Low Dose			67.0	70.0
Xanomeline Low Dose			67.0	66.0
Xanomeline Low Dose			64.0	68.0
Xanomeline Low Dose			68.0	70.0
Xanomeline Low Dose			72.0	66.0
Xanomeline Low Dose			74.0	68.0
Xanomeline Low Dose		Week 2	100.0	89.0	11.0
Xanomeline Low Dose		Week 2	102.0	97.0	5.0
Xanomeline Low Dose		Week 2	100.0	95.0	5.0
Xanomeline Low Dose			88.0	89.0
Xanomeline Low Dose			100.0	97.0
Xanomeline Low Dose			90.0	95.0
Placebo		Week 12	55.0	58.0	-3.0
Placebo		Week 12	49.0	52.0	-3.0
Placebo		Week 12	57.0	54.0	3.0
Placebo		Week 16	52.0	58.0	-6.0
Placebo		Week 16	49.0	52.0	-3.0
Placebo		Week 16	55.0	54.0	1.0
Placebo		Week 2	52.0	58.0	-6.0
Placebo		Week 2	56.0	52.0	4.0
Placebo		Week 2	58.0	54.0	4.0
Placebo		Week 20	54.0	58.0	-4.0
Placebo		Week 20	48.0	52.0	-4.0
Placebo		Week 20	56.0	54.0	2.0
Placebo		Week 24	48.0	58.0	-10.0
Placebo		Week 24	56.0	52.0	4.0
Placebo		Week 24	51.0	54.0	-3.0
Placebo		Week 4	41.0	58.0	-17.0
Placebo		Week 4	39.0	52.0	-13.0
Placebo		Week 4	50.0	54.0	-4.0
Placebo		Week 6	48.0	58.0	-10.0
Placebo		Week 6	52.0	52.0	0.0
Placebo		Week 6	54.0	54.0	0.0
Placebo		Week 8	49.0	58.0	-9.0
Placebo		Week 8	52.0	52.0	0.0
Placebo		Week 8	57.0	54.0	3.0
Placebo			54.0	58.0
Placebo			58.0	52.0
Placebo			58.0	54.0
Placebo			46.0	58.0
Placebo			52.0	52.0
Placebo			54.0	54.0
Placebo		Week 12	52.0	60.0	-8.0
Placebo		Week 12	69.0	72.0	-3.0
Placebo		Week 12	55.0	64.0	-9.0
Placebo		Week 16	71.0	60.0	11.0
Placebo		Week 16	61.0	72.0	-11.0
Placebo		Week 16	59.0	64.0	-5.0
Placebo		Week 2	59.0	60.0	-1.0
Placebo		Week 2	45.0	72.0	-27.0
Placebo		Week 2	45.0	64.0	-19.0
Placebo		Week 20	56.0	60.0	-4.0
Placebo		Week 20	56.0	72.0	-16.0
Placebo		Week 20	49.0	64.0	-15.0
Placebo		Week 24	63.0	60.0	3.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 24	56.0	64.0	-8.0
Placebo		Week 26	46.0	60.0	-14.0
Placebo		Week 26	61.0	72.0	-11.0
Placebo		Week 26	56.0	64.0	-8.0
Placebo		Week 4	54.0	60.0	-6.0
Placebo		Week 4	53.0	72.0	-19.0
Placebo		Week 4	53.0	64.0	-11.0
Placebo		Week 6	52.0	60.0	-8.0
Placebo		Week 6	49.0	72.0	-23.0
Placebo		Week 6	49.0	64.0	-15.0
Placebo		Week 8	63.0	60.0	3.0
Placebo		Week 8	54.0	72.0	-18.0
Placebo		Week 8	65.0	64.0	1.0
Placebo			49.0	60.0
Placebo			54.0	72.0
Placebo			58.0	64.0
Placebo			51.0	60.0
Placebo			51.0	72.0
Placebo			48.0	64.0
Xanomeline High Dose		Week 12	56.0	63.0	-7.0
Xanomeline High Dose		Week 12	60.0	60.0	0.0
Xanomeline High Dose		Week 12	60.0	65.0	-5.0
Xanomeline High Dose		Week 16	62.0	63.0	-1.0
Xanomeline High Dose		Week 16	60.0	60.0	0.0
Xanomeline High Dose		Week 16	64.0	65.0	-1.0
Xanomeline High Dose		Week 2	66.0	63.0	3.0
Xanomeline High Dose		Week 2	56.0	60.0	-4.0
Xanomeline High Dose		Week 2	66.0	65.0	1.0
Xanomeline High Dose		Week 20	58.0	63.0	-5.0
Xanomeline High Dose		Week 20	54.0	60.0	-6.0
Xanomeline High Dose		Week 20	66.0	65.0	1.0
Xanomeline High Dose		Week 24	68.0	63.0	5.0
Xanomeline High Dose		Week 24	60.0	60.0	0.0
Xanomeline High Dose		Week 24	62.0	65.0	-3.0
Xanomeline High Dose		Week 26	62.0	63.0	-1.0
Xanomeline High Dose		Week 26	56.0	60.0	-4.0
Xanomeline High Dose		Week 26	59.0	65.0	-6.0
Xanomeline High Dose		Week 4	54.0	63.0	-9.0
Xanomeline High Dose		Week 4	62.0	60.0	2.0
Xanomeline High Dose		Week 4	64.0	65.0	-1.0
Xanomeline High Dose		Week 6	64.0	63.0	1.0
Xanomeline High Dose		Week 6	54.0	60.0	-6.0
Xanomeline High Dose		Week 6	60.0	65.0	-5.0
Xanomeline High Dose		Week 8	63.0	63.0	0.0
Xanomeline High Dose		Week 8	54.0	60.0	-6.0
Xanomeline High Dose		Week 8	61.0	65.0	-4.0
Xanomeline High Dose			62.0	63.0
Xanomeline High Dose			61.0	60.0
Xanomeline High Dose			58.0	65.0
Xanomeline High Dose			60.0	63.0
Xanomeline High Dose			60.0	60.0
Xanomeline High Dose			59.0	65.0
Placebo		Week 2	67.0	69.0	-2.0
Placebo		Week 2	60.0	75.0	-15.0
Placebo		Week 2	61.0	74.0	-13.0
Placebo		Week 12	64.0	72.0	-8.0
Placebo		Week 12	67.0	68.0	-1.0
Placebo		Week 12	68.0	68.0	0.0
Placebo		Week 16	73.0	72.0	1.0
Placebo		Week 16	72.0	68.0	4.0
Placebo		Week 16	72.0	68.0	4.0
Placebo		Week 2	69.0	72.0	-3.0
Placebo		Week 2	74.0	68.0	6.0
Placebo		Week 2	71.0	68.0	3.0
Placebo		Week 20	65.0	72.0	-7.0
Placebo		Week 20	72.0	68.0	4.0
Placebo		Week 20	68.0	68.0	0.0
Placebo		Week 24	76.0	72.0	4.0
Placebo		Week 24	71.0	68.0	3.0
Placebo		Week 24	67.0	68.0	-1.0
Placebo		Week 26	72.0	72.0	0.0
Placebo		Week 26	68.0	68.0	0.0
Placebo		Week 26	69.0	68.0	1.0
Placebo		Week 4	80.0	72.0	8.0
Placebo		Week 4	75.0	68.0	7.0
Placebo		Week 4	77.0	68.0	9.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	68.0	68.0	0.0
Placebo		Week 6	73.0	68.0	5.0
Placebo		Week 8	64.0	72.0	-8.0
Placebo		Week 8	68.0	68.0	0.0
Placebo		Week 8	64.0	68.0	-4.0
Placebo			68.0	72.0
Placebo			72.0	68.0
Placebo			68.0	68.0
Placebo			69.0	72.0
Placebo			72.0	68.0
Placebo			76.0	68.0
Placebo		Week 12	64.0	66.0	-2.0
Placebo		Week 12	60.0	68.0	-8.0
Placebo		Week 12	64.0	68.0	-4.0
Placebo		Week 16	54.0	66.0	-12.0
Placebo		Week 16	64.0	68.0	-4.0
Placebo		Week 16	61.0	68.0	-7.0
Placebo		Week 2	68.0	66.0	2.0
Placebo		Week 2	64.0	68.0	-4.0
Placebo		Week 2	65.0	68.0	-3.0
Placebo		Week 20	67.0	66.0	1.0
Placebo		Week 20	67.0	68.0	-1.0
Placebo		Week 20	72.0	68.0	4.0
Placebo		Week 24	62.0	66.0	-4.0
Placebo		Week 24	65.0	68.0	-3.0
Placebo		Week 24	59.0	68.0	-9.0
Placebo		Week 26	67.0	66.0	1.0
Placebo		Week 26	58.0	68.0	-10.0
Placebo		Week 26	54.0	68.0	-14.0
Placebo		Week 4	57.0	66.0	-9.0
Placebo		Week 4	64.0	68.0	-4.0
Placebo		Week 4	64.0	68.0	-4.0
Placebo		Week 6	57.0	66.0	-9.0
Placebo		Week 6	54.0	68.0	-14.0
Placebo		Week 6	65.0	68.0	-3.0
Placebo		Week 8	68.0	66.0	2.0
Placebo		Week 8	63.0	68.0	-5.0
Placebo		Week 8	65.0	68.0	-3.0
Placebo			56.0	66.0
Placebo			53.0	68.0
Placebo			60.0	68.0
Placebo			67.0	66.0
Placebo			52.0	68.0
Placebo			65.0	68.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 2	86.0	80.0	6.0
Xanomeline Low Dose		Week 2	81.0	76.0	5.0
Xanomeline Low Dose		Week 4	69.0	72.0	-3.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	84.0	76.0	8.0
Xanomeline Low Dose		Week 6	78.0	72.0	6.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	75.0	76.0	-1.0
Placebo		Week 12	79.0	72.0	7.0
Placebo		Week 12	85.0	78.0	7.0
Placebo		Week 12	92.0	76.0	16.0
Placebo		Week 16	79.0	72.0	7.0
Placebo		Week 16	88.0	78.0	10.0
Placebo		Week 16	84.0	76.0	8.0
Placebo		Week 2	87.0	72.0	15.0
Placebo		Week 2	66.0	78.0	-12.0
Placebo		Week 2	68.0	76.0	-8.0
Placebo		Week 20	65.0	72.0	-7.0
Placebo		Week 20	72.0	78.0	-6.0
Placebo		Week 20	73.0	76.0	-3.0
Placebo		Week 24	76.0	72.0	4.0
Placebo		Week 24	82.0	78.0	4.0
Placebo		Week 24	84.0	76.0	8.0
Placebo		Week 26	67.0	72.0	-5.0
Placebo		Week 26	60.0	78.0	-18.0
Placebo		Week 26	62.0	76.0	-14.0
Placebo		Week 4	64.0	72.0	-8.0
Placebo		Week 4	62.0	78.0	-16.0
Placebo		Week 4	64.0	76.0	-12.0
Placebo		Week 6	61.0	72.0	-11.0
Placebo		Week 6	73.0	78.0	-5.0
Placebo		Week 6	65.0	76.0	-11.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	76.0	78.0	-2.0
Placebo		Week 8	84.0	76.0	8.0
Placebo			68.0	72.0
Placebo			70.0	78.0
Placebo			70.0	76.0
Placebo			68.0	72.0
Placebo			72.0	78.0
Placebo			76.0	76.0
Xanomeline Low Dose		Week 12	73.0	69.0	4.0
Xanomeline Low Dose		Week 12	70.0	66.0	4.0
Xanomeline Low Dose		Week 12	68.0	82.0	-14.0
Xanomeline Low Dose		Week 16	68.0	69.0	-1.0
Xanomeline Low Dose		Week 16	80.0	66.0	14.0
Xanomeline Low Dose		Week 16	69.0	82.0	-13.0
Xanomeline Low Dose		Week 2	85.0	69.0	16.0
Xanomeline Low Dose		Week 2	79.0	66.0	13.0
Xanomeline Low Dose		Week 2	70.0	82.0	-12.0
Xanomeline Low Dose		Week 20	71.0	69.0	2.0
Xanomeline Low Dose		Week 20	74.0	66.0	8.0
Xanomeline Low Dose		Week 20	69.0	82.0	-13.0
Xanomeline Low Dose		Week 24	64.0	69.0	-5.0
Xanomeline Low Dose		Week 24	64.0	66.0	-2.0
Xanomeline Low Dose		Week 24	81.0	82.0	-1.0
Xanomeline Low Dose		Week 26	85.0	69.0	16.0
Xanomeline Low Dose		Week 26	62.0	66.0	-4.0
Xanomeline Low Dose		Week 26	67.0	82.0	-15.0
Xanomeline Low Dose		Week 4	81.0	69.0	12.0
Xanomeline Low Dose		Week 4	66.0	66.0	0.0
Xanomeline Low Dose		Week 4	74.0	82.0	-8.0
Xanomeline Low Dose		Week 6	68.0	69.0	-1.0
Xanomeline Low Dose		Week 6	57.0	66.0	-9.0
Xanomeline Low Dose		Week 6	65.0	82.0	-17.0
Xanomeline Low Dose		Week 8	70.0	69.0	1.0
Xanomeline Low Dose		Week 8	74.0	66.0	8.0
Xanomeline Low Dose		Week 8	74.0	82.0	-8.0
Xanomeline Low Dose			72.0	69.0
Xanomeline Low Dose			75.0	66.0
Xanomeline Low Dose			75.0	82.0
Xanomeline Low Dose			88.0	69.0
Xanomeline Low Dose			76.0	66.0
Xanomeline Low Dose			80.0	82.0
Xanomeline High Dose		Week 2	88.0	89.0	-1.0
Xanomeline High Dose		Week 2	81.0	84.0	-3.0
Xanomeline High Dose		Week 2	82.0	76.0	6.0
Xanomeline High Dose		Week 4	87.0	89.0	-2.0
Xanomeline High Dose		Week 4	79.0	84.0	-5.0
Xanomeline High Dose		Week 4	84.0	76.0	8.0
Xanomeline High Dose			79.0	89.0
Xanomeline High Dose			70.0	84.0
Xanomeline High Dose			68.0	76.0
Xanomeline High Dose			71.0	89.0
Xanomeline High Dose			80.0	84.0
Xanomeline High Dose			77.0	76.0
Xanomeline Low Dose		Week 2	70.0	64.0	6.0
Xanomeline Low Dose		Week 2	60.0	56.0	4.0
Xanomeline Low Dose		Week 2	60.0	59.0	1.0
Xanomeline Low Dose		Week 4	68.0	64.0	4.0
Xanomeline Low Dose		Week 4	70.0	56.0	14.0
Xanomeline Low Dose		Week 4	70.0	59.0	11.0
Xanomeline Low Dose		Week 6	52.0	64.0	-12.0
Xanomeline Low Dose		Week 6	56.0	56.0	0.0
Xanomeline Low Dose		Week 6	60.0	59.0	1.0
Xanomeline Low Dose		Week 8	70.0	64.0	6.0
Xanomeline Low Dose		Week 8	66.0	56.0	10.0
Xanomeline Low Dose		Week 8	66.0	59.0	7.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			68.0	56.0
Xanomeline Low Dose			62.0	59.0
Xanomeline Low Dose			60.0	64.0
Xanomeline Low Dose			56.0	56.0
Xanomeline Low Dose			52.0	59.0
Placebo		Week 12	72.0	56.0	16.0
Placebo		Week 12	72.0	66.0	6.0
Placebo		Week 12	70.0	68.0	2.0
Placebo		Week 16	60.0	56.0	4.0
Placebo		Week 16	68.0	66.0	2.0
Placebo		Week 16	70.0	68.0	2.0
Placebo		Week 2	62.0	56.0	6.0
Placebo		Week 2	72.0	66.0	6.0
Placebo		Week 2	68.0	68.0	0.0
Placebo		Week 20	72.0	56.0	16.0
Placebo		Week 20	68.0	66.0	2.0
Placebo		Week 20	72.0	68.0	4.0
Placebo		Week 24	76.0	56.0	20.0
Placebo		Week 24	74.0	66.0	8.0
Placebo		Week 24	78.0	68.0	10.0
Placebo		Week 26	74.0	56.0	18.0
Placebo		Week 26	78.0	66.0	12.0
Placebo		Week 26	78.0	68.0	10.0
Placebo		Week 4	70.0	56.0	14.0
Placebo		Week 4	82.0	66.0	16.0
Placebo		Week 4	80.0	68.0	12.0
Placebo		Week 6	70.0	56.0	14.0
Placebo		Week 6	78.0	66.0	12.0
Placebo		Week 6	80.0	68.0	12.0
Placebo		Week 8	70.0	56.0	14.0
Placebo		Week 8	66.0	66.0	0.0
Placebo		Week 8	68.0	68.0	0.0
Placebo			70.0	56.0
Placebo			68.0	66.0
Placebo			76.0	68.0
Placebo			66.0	56.0
Placebo			68.0	66.0
Placebo			70.0	68.0
Xanomeline High Dose		Week 12	82.0	86.0	-4.0
Xanomeline High Dose		Week 12	80.0	88.0	-8.0
Xanomeline High Dose		Week 12	88.0	80.0	8.0
Xanomeline High Dose		Week 2	88.0	86.0	2.0
Xanomeline High Dose		Week 2	89.0	88.0	1.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 4	81.0	86.0	-5.0
Xanomeline High Dose		Week 4	88.0	88.0	0.0
Xanomeline High Dose		Week 4	85.0	80.0	5.0
Xanomeline High Dose		Week 6	90.0	86.0	4.0
Xanomeline High Dose		Week 6	90.0	88.0	2.0
Xanomeline High Dose		Week 6	82.0	80.0	2.0
Xanomeline High Dose		Week 8	94.0	86.0	8.0
Xanomeline High Dose		Week 8	90.0	88.0	2.0
Xanomeline High Dose		Week 8	90.0	80.0	10.0
Xanomeline High Dose			88.0	86.0
Xanomeline High Dose			89.0	88.0
Xanomeline High Dose			90.0	80.0
Xanomeline High Dose			90.0	86.0
Xanomeline High Dose			88.0	88.0
Xanomeline High Dose			90.0	80.0
Xanomeline Low Dose		Week 12	76.0	80.0	-4.0
Xanomeline Low Dose		Week 12	80.0	82.0	-2.0
Xanomeline Low Dose		Week 12	82.0	72.0	10.0
Xanomeline Low Dose		Week 2	68.0	80.0	-12.0
Xanomeline Low Dose		Week 2	74.0	82.0	-8.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	80.0	82.0	-2.0
Xanomeline Low Dose		Week 4	78.0	72.0	6.0
Xanomeline Low Dose		Week 6	72.0	80.0	-8.0
Xanomeline Low Dose		Week 6	70.0	82.0	-12.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 8	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	84.0	82.0	2.0
Xanomeline Low Dose		Week 8	84.0	72.0	12.0
Xanomeline Low Dose			64.0	80.0
Xanomeline Low Dose			70.0	82.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			80.0	82.0
Xanomeline Low Dose			80.0	72.0
Placebo		Week 2	74.0	70.0	4.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	80.0	70.0	10.0
Placebo		Week 4	80.0	70.0	10.0
Placebo		Week 4	80.0	72.0	8.0
Placebo		Week 4	80.0	70.0	10.0
Placebo			80.0	70.0
Placebo			78.0	72.0
Placebo			80.0	70.0
Placebo			80.0	70.0
Placebo			84.0	72.0
Placebo			80.0	70.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	80.0	84.0	-4.0
Placebo		Week 12	80.0	88.0	-8.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	78.0	84.0	-6.0
Placebo		Week 16	76.0	88.0	-12.0
Placebo		Week 2	88.0	80.0	8.0
Placebo		Week 2	90.0	84.0	6.0
Placebo		Week 2	90.0	88.0	2.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	78.0	84.0	-6.0
Placebo		Week 20	78.0	88.0	-10.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 24	78.0	88.0	-10.0
Placebo		Week 26	70.0	80.0	-10.0
Placebo		Week 26	74.0	84.0	-10.0
Placebo		Week 26	74.0	88.0	-14.0
Placebo		Week 4	78.0	80.0	-2.0
Placebo		Week 4	80.0	84.0	-4.0
Placebo		Week 4	80.0	88.0	-8.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 6	72.0	84.0	-12.0
Placebo		Week 6	70.0	88.0	-18.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	84.0	84.0	0.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo			80.0	80.0
Placebo			80.0	84.0
Placebo			84.0	88.0
Placebo			78.0	80.0
Placebo			80.0	84.0
Placebo			79.0	88.0
Xanomeline Low Dose		Week 12	72.0	68.0	4.0
Xanomeline Low Dose		Week 12	70.0	68.0	2.0
Xanomeline Low Dose		Week 12	70.0	72.0	-2.0
Xanomeline Low Dose		Week 16	82.0	68.0	14.0
Xanomeline Low Dose		Week 16	70.0	68.0	2.0
Xanomeline Low Dose		Week 16	80.0	72.0	8.0
Xanomeline Low Dose		Week 2	60.0	68.0	-8.0
Xanomeline Low Dose		Week 2	70.0	68.0	2.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 4	70.0	68.0	2.0
Xanomeline Low Dose		Week 4	72.0	68.0	4.0
Xanomeline Low Dose		Week 4	68.0	72.0	-4.0
Xanomeline Low Dose		Week 6	64.0	68.0	-4.0
Xanomeline Low Dose		Week 6	70.0	68.0	2.0
Xanomeline Low Dose		Week 6	60.0	72.0	-12.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	70.0	68.0	2.0
Xanomeline Low Dose		Week 8	70.0	72.0	-2.0
Xanomeline Low Dose			78.0	68.0
Xanomeline Low Dose			78.0	68.0
Xanomeline Low Dose			78.0	72.0
Xanomeline Low Dose			72.0	68.0
Xanomeline Low Dose			72.0	68.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	84.0	70.0	14.0
Xanomeline Low Dose		Week 6	82.0	80.0	2.0
Xanomeline Low Dose		Week 6	72.0	80.0	-8.0
Xanomeline Low Dose		Week 6	66.0	70.0	-4.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			78.0	80.0
Xanomeline Low Dose			78.0	70.0
Placebo		Week 12	68.0	70.0	-2.0
Placebo		Week 12	68.0	80.0	-12.0
Placebo		Week 12	68.0	70.0	-2.0
Placebo		Week 16	62.0	70.0	-8.0
Placebo		Week 16	64.0	80.0	-16.0
Placebo		Week 16	68.0	70.0	-2.0
Placebo		Week 2	74.0	70.0	4.0
Placebo		Week 2	74.0	80.0	-6.0
Placebo		Week 2	74.0	70.0	4.0
Placebo		Week 20	72.0	70.0	2.0
Placebo		Week 20	68.0	80.0	-12.0
Placebo		Week 20	68.0	70.0	-2.0
Placebo		Week 24	72.0	70.0	2.0
Placebo		Week 24	72.0	80.0	-8.0
Placebo		Week 24	70.0	70.0	0.0
Placebo		Week 26	68.0	70.0	-2.0
Placebo		Week 26	68.0	80.0	-12.0
Placebo		Week 26	66.0	70.0	-4.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 4	68.0	80.0	-12.0
Placebo		Week 4	76.0	70.0	6.0
Placebo		Week 6	70.0	70.0	0.0
Placebo		Week 6	74.0	80.0	-6.0
Placebo		Week 6	72.0	70.0	2.0
Placebo		Week 8	80.0	70.0	10.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	70.0	70.0	0.0
Placebo			72.0	70.0
Placebo			72.0	80.0
Placebo			76.0	70.0
Placebo			74.0	70.0
Placebo			72.0	80.0
Placebo			70.0	70.0
Xanomeline High Dose		Week 12	80.0	92.0	-12.0
Xanomeline High Dose		Week 12	76.0	94.0	-18.0
Xanomeline High Dose		Week 12	84.0	90.0	-6.0
Xanomeline High Dose		Week 16	90.0	92.0	-2.0
Xanomeline High Dose		Week 16	92.0	94.0	-2.0
Xanomeline High Dose		Week 16	90.0	90.0	0.0
Xanomeline High Dose		Week 2	82.0	92.0	-10.0
Xanomeline High Dose		Week 2	80.0	94.0	-14.0
Xanomeline High Dose		Week 2	82.0	90.0	-8.0
Xanomeline High Dose		Week 20	88.0	92.0	-4.0
Xanomeline High Dose		Week 20	90.0	94.0	-4.0
Xanomeline High Dose		Week 20	92.0	90.0	2.0
Xanomeline High Dose		Week 24	80.0	92.0	-12.0
Xanomeline High Dose		Week 24	80.0	94.0	-14.0
Xanomeline High Dose		Week 24	80.0	90.0	-10.0
Xanomeline High Dose		Week 4	80.0	92.0	-12.0
Xanomeline High Dose		Week 4	74.0	94.0	-20.0
Xanomeline High Dose		Week 4	76.0	90.0	-14.0
Xanomeline High Dose		Week 6	80.0	92.0	-12.0
Xanomeline High Dose		Week 6	78.0	94.0	-16.0
Xanomeline High Dose		Week 6	80.0	90.0	-10.0
Xanomeline High Dose		Week 8	74.0	92.0	-18.0
Xanomeline High Dose		Week 8	78.0	94.0	-16.0
Xanomeline High Dose		Week 8	80.0	90.0	-10.0
Xanomeline High Dose			78.0	92.0
Xanomeline High Dose			82.0	94.0
Xanomeline High Dose			76.0	90.0
Xanomeline High Dose			80.0	92.0
Xanomeline High Dose			76.0	94.0
Xanomeline High Dose			80.0	90.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	78.0	78.0	0.0
Xanomeline High Dose		Week 16	80.0	78.0	2.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 16	80.0	78.0	2.0
Xanomeline High Dose		Week 2	80.0	78.0	2.0
Xanomeline High Dose		Week 2	66.0	80.0	-14.0
Xanomeline High Dose		Week 2	62.0	78.0	-16.0
Xanomeline High Dose		Week 4	82.0	78.0	4.0
Xanomeline High Dose		Week 4	70.0	80.0	-10.0
Xanomeline High Dose		Week 4	88.0	78.0	10.0
Xanomeline High Dose		Week 6	82.0	78.0	4.0
Xanomeline High Dose		Week 6	70.0	80.0	-10.0
Xanomeline High Dose		Week 6	72.0	78.0	-6.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose		Week 8	78.0	80.0	-2.0
Xanomeline High Dose		Week 8	78.0	78.0	0.0
Xanomeline High Dose			78.0	78.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	78.0
Xanomeline High Dose			80.0	78.0
Xanomeline High Dose			72.0	80.0
Xanomeline High Dose			80.0	78.0
Placebo		Week 12	60.0	70.0	-10.0
Placebo		Week 12	70.0	66.0	4.0
Placebo		Week 12	68.0	70.0	-2.0
Placebo		Week 16	68.0	70.0	-2.0
Placebo		Week 16	70.0	66.0	4.0
Placebo		Week 16	70.0	70.0	0.0
Placebo		Week 2	68.0	70.0	-2.0
Placebo		Week 2	70.0	66.0	4.0
Placebo		Week 2	76.0	70.0	6.0
Placebo		Week 20	60.0	70.0	-10.0
Placebo		Week 20	60.0	66.0	-6.0
Placebo		Week 20	60.0	70.0	-10.0
Placebo		Week 24	68.0	70.0	-2.0
Placebo		Week 24	64.0	66.0	-2.0
Placebo		Week 24	64.0	70.0	-6.0
Placebo		Week 26	58.0	70.0	-12.0
Placebo		Week 26	56.0	66.0	-10.0
Placebo		Week 26	66.0	70.0	-4.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 4	74.0	66.0	8.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 6	70.0	70.0	0.0
Placebo		Week 6	60.0	66.0	-6.0
Placebo		Week 6	60.0	70.0	-10.0
Placebo		Week 8	72.0	70.0	2.0
Placebo		Week 8	70.0	66.0	4.0
Placebo		Week 8	60.0	70.0	-10.0
Placebo			66.0	70.0
Placebo			70.0	66.0
Placebo			74.0	70.0
Placebo			72.0	70.0
Placebo			74.0	66.0
Placebo			72.0	70.0
Xanomeline High Dose		Week 2	88.0	80.0	8.0
Xanomeline High Dose		Week 2	90.0	70.0	20.0
Xanomeline High Dose		Week 2	88.0	80.0	8.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 4	74.0	70.0	4.0
Xanomeline High Dose		Week 4	70.0	80.0	-10.0
Xanomeline High Dose			60.0	80.0
Xanomeline High Dose			62.0	70.0
Xanomeline High Dose			60.0	80.0
Xanomeline High Dose			72.0	80.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			70.0	80.0
Xanomeline Low Dose		Week 12	80.0	80.0	0.0
Xanomeline Low Dose		Week 12	88.0	84.0	4.0
Xanomeline Low Dose		Week 12	82.0	86.0	-4.0
Xanomeline Low Dose		Week 16	70.0	80.0	-10.0
Xanomeline Low Dose		Week 16	76.0	84.0	-8.0
Xanomeline Low Dose		Week 16	80.0	86.0	-6.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	74.0	84.0	-10.0
Xanomeline Low Dose		Week 2	72.0	86.0	-14.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 20	88.0	84.0	4.0
Xanomeline Low Dose		Week 20	80.0	86.0	-6.0
Xanomeline Low Dose		Week 24	80.0	80.0	0.0
Xanomeline Low Dose		Week 24	86.0	84.0	2.0
Xanomeline Low Dose		Week 24	82.0	86.0	-4.0
Xanomeline Low Dose		Week 26	72.0	80.0	-8.0
Xanomeline Low Dose		Week 26	76.0	84.0	-8.0
Xanomeline Low Dose		Week 26	78.0	86.0	-8.0
Xanomeline Low Dose		Week 4	74.0	80.0	-6.0
Xanomeline Low Dose		Week 4	80.0	84.0	-4.0
Xanomeline Low Dose		Week 4	72.0	86.0	-14.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	88.0	84.0	4.0
Xanomeline Low Dose		Week 6	80.0	86.0	-6.0
Xanomeline Low Dose		Week 8	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	80.0	84.0	-4.0
Xanomeline Low Dose		Week 8	82.0	86.0	-4.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			90.0	84.0
Xanomeline Low Dose			80.0	86.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			70.0	84.0
Xanomeline Low Dose			74.0	86.0
Xanomeline High Dose		Week 12	82.0	82.0	0.0
Xanomeline High Dose		Week 12	82.0	90.0	-8.0
Xanomeline High Dose		Week 12	82.0	90.0	-8.0
Xanomeline High Dose		Week 16	88.0	82.0	6.0
Xanomeline High Dose		Week 16	90.0	90.0	0.0
Xanomeline High Dose		Week 16	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	92.0	82.0	10.0
Xanomeline High Dose		Week 2	94.0	90.0	4.0
Xanomeline High Dose		Week 2	90.0	90.0	0.0
Xanomeline High Dose		Week 20	90.0	82.0	8.0
Xanomeline High Dose		Week 20	88.0	90.0	-2.0
Xanomeline High Dose		Week 20	90.0	90.0	0.0
Xanomeline High Dose		Week 24	80.0	82.0	-2.0
Xanomeline High Dose		Week 24	84.0	90.0	-6.0
Xanomeline High Dose		Week 24	82.0	90.0	-8.0
Xanomeline High Dose		Week 26	84.0	82.0	2.0
Xanomeline High Dose		Week 26	86.0	90.0	-4.0
Xanomeline High Dose		Week 26	86.0	90.0	-4.0
Xanomeline High Dose		Week 4	90.0	82.0	8.0
Xanomeline High Dose		Week 4	92.0	90.0	2.0
Xanomeline High Dose		Week 4	90.0	90.0	0.0
Xanomeline High Dose		Week 6	84.0	82.0	2.0
Xanomeline High Dose		Week 6	80.0	90.0	-10.0
Xanomeline High Dose		Week 6	80.0	90.0	-10.0
Xanomeline High Dose		Week 8	80.0	82.0	-2.0
Xanomeline High Dose		Week 8	80.0	90.0	-10.0
Xanomeline High Dose		Week 8	80.0	90.0	-10.0
Xanomeline High Dose			90.0	82.0
Xanomeline High Dose			94.0	90.0
Xanomeline High Dose			94.0	90.0
Xanomeline High Dose			88.0	82.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			86.0	90.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 4	72.0	80.0	-8.0
Xanomeline High Dose		Week 4	78.0	84.0	-6.0
Xanomeline High Dose		Week 4	78.0	76.0	2.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			86.0	84.0
Xanomeline High Dose			78.0	76.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			78.0	84.0
Xanomeline High Dose			78.0	76.0
Xanomeline Low Dose		Week 2	66.0	76.0	-10.0
Xanomeline Low Dose		Week 2	68.0	76.0	-8.0
Xanomeline Low Dose		Week 2	72.0	78.0	-6.0
Xanomeline Low Dose			72.0	76.0
Xanomeline Low Dose			74.0	76.0
Xanomeline Low Dose			86.0	78.0
Placebo		Week 12	80.0	92.0	-12.0
Placebo		Week 12	74.0	92.0	-18.0
Placebo		Week 12	74.0	90.0	-16.0
Placebo		Week 16	86.0	92.0	-6.0
Placebo		Week 16	76.0	92.0	-16.0
Placebo		Week 16	74.0	90.0	-16.0
Placebo		Week 2	82.0	92.0	-10.0
Placebo		Week 2	92.0	92.0	0.0
Placebo		Week 2	90.0	90.0	0.0
Placebo		Week 4	84.0	92.0	-8.0
Placebo		Week 4	88.0	92.0	-4.0
Placebo		Week 4	86.0	90.0	-4.0
Placebo		Week 6	90.0	92.0	-2.0
Placebo		Week 6	82.0	92.0	-10.0
Placebo		Week 6	86.0	90.0	-4.0
Placebo		Week 8	92.0	92.0	0.0
Placebo		Week 8	90.0	92.0	-2.0
Placebo		Week 8	86.0	90.0	-4.0
Placebo			78.0	92.0
Placebo			84.0	92.0
Placebo			84.0	90.0
Placebo			84.0	92.0
Placebo			84.0	92.0
Placebo			88.0	90.0
Xanomeline High Dose		Week 2	60.0	70.0	-10.0
Xanomeline High Dose		Week 2	58.0	66.0	-8.0
Xanomeline High Dose		Week 2	56.0	68.0	-12.0
Xanomeline High Dose		Week 4	66.0	70.0	-4.0
Xanomeline High Dose		Week 4	60.0	66.0	-6.0
Xanomeline High Dose		Week 4	60.0	68.0	-8.0
Xanomeline High Dose			64.0	70.0
Xanomeline High Dose			66.0	66.0
Xanomeline High Dose			70.0	68.0
Xanomeline Low Dose		Week 2	78.0	82.0	-4.0
Xanomeline Low Dose		Week 2	90.0	82.0	8.0
Xanomeline Low Dose		Week 2	82.0	86.0	-4.0
Xanomeline Low Dose			88.0	82.0
Xanomeline Low Dose			88.0	82.0
Xanomeline Low Dose			96.0	86.0
Xanomeline High Dose		Week 2	86.0	86.0	0.0
Xanomeline High Dose		Week 2	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	82.0	92.0	-10.0
Xanomeline High Dose		Week 4	84.0	86.0	-2.0
Xanomeline High Dose		Week 4	82.0	90.0	-8.0
Xanomeline High Dose		Week 4	86.0	92.0	-6.0
Xanomeline High Dose		Week 6	80.0	86.0	-6.0
Xanomeline High Dose		Week 6	76.0	90.0	-14.0
Xanomeline High Dose		Week 6	76.0	92.0	-16.0
Xanomeline High Dose		Week 8	86.0	86.0	0.0
Xanomeline High Dose		Week 8	76.0	90.0	-14.0
Xanomeline High Dose		Week 8	72.0	92.0	-20.0
Xanomeline High Dose			74.0	86.0
Xanomeline High Dose			80.0	90.0
Xanomeline High Dose			82.0	92.0
Xanomeline High Dose			72.0	86.0
Xanomeline High Dose			74.0	90.0
Xanomeline High Dose			74.0	92.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	86.0	80.0	6.0
Xanomeline High Dose		Week 2	84.0	84.0	0.0
Xanomeline High Dose		Week 4	88.0	80.0	8.0
Xanomeline High Dose		Week 4	86.0	80.0	6.0
Xanomeline High Dose		Week 4	86.0	84.0	2.0
Xanomeline High Dose		Week 6	86.0	80.0	6.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 6	84.0	84.0	0.0
Xanomeline High Dose			92.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			80.0	84.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			88.0	84.0
Xanomeline High Dose		Week 12	78.0	90.0	-12.0
Xanomeline High Dose		Week 12	88.0	90.0	-2.0
Xanomeline High Dose		Week 12	78.0	86.0	-8.0
Xanomeline High Dose		Week 2	82.0	90.0	-8.0
Xanomeline High Dose		Week 2	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	86.0	86.0	0.0
Xanomeline High Dose		Week 4	88.0	90.0	-2.0
Xanomeline High Dose		Week 4	92.0	90.0	2.0
Xanomeline High Dose		Week 4	80.0	86.0	-6.0
Xanomeline High Dose		Week 6	84.0	90.0	-6.0
Xanomeline High Dose		Week 6	78.0	90.0	-12.0
Xanomeline High Dose		Week 6	76.0	86.0	-10.0
Xanomeline High Dose		Week 8	82.0	90.0	-8.0
Xanomeline High Dose		Week 8	88.0	90.0	-2.0
Xanomeline High Dose		Week 8	86.0	86.0	0.0
Xanomeline High Dose			76.0	90.0
Xanomeline High Dose			82.0	90.0
Xanomeline High Dose			82.0	86.0
Xanomeline High Dose			84.0	90.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			90.0	86.0
Xanomeline Low Dose		Week 12	86.0	78.0	8.0
Xanomeline Low Dose		Week 12	74.0	70.0	4.0
Xanomeline Low Dose		Week 12	76.0	70.0	6.0
Xanomeline Low Dose		Week 16	82.0	78.0	4.0
Xanomeline Low Dose		Week 16	80.0	70.0	10.0
Xanomeline Low Dose		Week 16	84.0	70.0	14.0
Xanomeline Low Dose		Week 2	78.0	78.0	0.0
Xanomeline Low Dose		Week 2	74.0	70.0	4.0
Xanomeline Low Dose		Week 2	78.0	70.0	8.0
Xanomeline Low Dose		Week 20	84.0	78.0	6.0
Xanomeline Low Dose		Week 20	80.0	70.0	10.0
Xanomeline Low Dose		Week 20	82.0	70.0	12.0
Xanomeline Low Dose		Week 4	70.0	78.0	-8.0
Xanomeline Low Dose		Week 4	72.0	70.0	2.0
Xanomeline Low Dose		Week 4	76.0	70.0	6.0
Xanomeline Low Dose		Week 6	64.0	78.0	-14.0
Xanomeline Low Dose		Week 6	74.0	70.0	4.0
Xanomeline Low Dose		Week 6	74.0	70.0	4.0
Xanomeline Low Dose		Week 8	66.0	78.0	-12.0
Xanomeline Low Dose		Week 8	70.0	70.0	0.0
Xanomeline Low Dose		Week 8	70.0	70.0	0.0
Xanomeline Low Dose			84.0	78.0
Xanomeline Low Dose			84.0	70.0
Xanomeline Low Dose			80.0	70.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			68.0	70.0
Xanomeline Low Dose			68.0	70.0
Xanomeline Low Dose		Week 2	84.0	76.0	8.0
Xanomeline Low Dose		Week 2	82.0	82.0	0.0
Xanomeline Low Dose		Week 2	86.0	76.0	10.0
Xanomeline Low Dose		Week 4	90.0	76.0	14.0
Xanomeline Low Dose		Week 4	88.0	82.0	6.0
Xanomeline Low Dose		Week 4	92.0	76.0	16.0
Xanomeline Low Dose		Week 6	78.0	76.0	2.0
Xanomeline Low Dose		Week 6	82.0	82.0	0.0
Xanomeline Low Dose		Week 6	84.0	76.0	8.0
Xanomeline Low Dose		Week 8	76.0	76.0	0.0
Xanomeline Low Dose		Week 8	88.0	82.0	6.0
Xanomeline Low Dose		Week 8	74.0	76.0	-2.0
Xanomeline Low Dose			80.0	76.0
Xanomeline Low Dose			80.0	82.0
Xanomeline Low Dose			80.0	76.0
Xanomeline Low Dose			80.0	76.0
Xanomeline Low Dose			84.0	82.0
Xanomeline Low Dose			88.0	76.0
Placebo		Week 12	66.0	60.0	6.0
Placebo		Week 12	60.0	74.0	-14.0
Placebo		Week 12	62.0	72.0	-10.0
Placebo		Week 16	64.0	60.0	4.0
Placebo		Week 16	62.0	74.0	-12.0
Placebo		Week 16	62.0	72.0	-10.0
Placebo		Week 2	72.0	60.0	12.0
Placebo		Week 2	64.0	74.0	-10.0
Placebo		Week 2	68.0	72.0	-4.0
Placebo		Week 20	70.0	60.0	10.0
Placebo		Week 20	64.0	74.0	-10.0
Placebo		Week 20	64.0	72.0	-8.0
Placebo		Week 24	68.0	60.0	8.0
Placebo		Week 24	66.0	74.0	-8.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 26	64.0	60.0	4.0
Placebo		Week 26	66.0	74.0	-8.0
Placebo		Week 26	68.0	72.0	-4.0
Placebo		Week 4	62.0	60.0	2.0
Placebo		Week 4	60.0	74.0	-14.0
Placebo		Week 4	60.0	72.0	-12.0
Placebo		Week 6	72.0	60.0	12.0
Placebo		Week 6	68.0	74.0	-6.0
Placebo		Week 6	66.0	72.0	-6.0
Placebo		Week 8	60.0	60.0	0.0
Placebo		Week 8	70.0	74.0	-4.0
Placebo		Week 8	66.0	72.0	-6.0
Placebo			64.0	60.0
Placebo			68.0	74.0
Placebo			68.0	72.0
Placebo			66.0	60.0
Placebo			60.0	74.0
Placebo			58.0	72.0
Xanomeline Low Dose		Week 12	66.0	76.0	-10.0
Xanomeline Low Dose		Week 12	60.0	74.0	-14.0
Xanomeline Low Dose		Week 12	64.0	80.0	-16.0
Xanomeline Low Dose		Week 16	68.0	76.0	-8.0
Xanomeline Low Dose		Week 16	70.0	74.0	-4.0
Xanomeline Low Dose		Week 16	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	76.0	76.0	0.0
Xanomeline Low Dose		Week 2	80.0	74.0	6.0
Xanomeline Low Dose		Week 2	74.0	80.0	-6.0
Xanomeline Low Dose		Week 20	64.0	76.0	-12.0
Xanomeline Low Dose		Week 20	68.0	74.0	-6.0
Xanomeline Low Dose		Week 20	76.0	80.0	-4.0
Xanomeline Low Dose		Week 24	72.0	76.0	-4.0
Xanomeline Low Dose		Week 24	80.0	74.0	6.0
Xanomeline Low Dose		Week 24	74.0	80.0	-6.0
Xanomeline Low Dose		Week 26	68.0	76.0	-8.0
Xanomeline Low Dose		Week 26	78.0	74.0	4.0
Xanomeline Low Dose		Week 26	70.0	80.0	-10.0
Xanomeline Low Dose		Week 4	80.0	76.0	4.0
Xanomeline Low Dose		Week 4	82.0	74.0	8.0
Xanomeline Low Dose		Week 4	76.0	80.0	-4.0
Xanomeline Low Dose		Week 6	74.0	76.0	-2.0
Xanomeline Low Dose		Week 6	76.0	74.0	2.0
Xanomeline Low Dose		Week 6	76.0	80.0	-4.0
Xanomeline Low Dose		Week 8	70.0	76.0	-6.0
Xanomeline Low Dose		Week 8	72.0	74.0	-2.0
Xanomeline Low Dose		Week 8	74.0	80.0	-6.0
Xanomeline Low Dose			76.0	76.0
Xanomeline Low Dose			82.0	74.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			70.0	76.0
Xanomeline Low Dose			78.0	74.0
Xanomeline Low Dose			76.0	80.0
Placebo		Week 12	64.0	62.0	2.0
Placebo		Week 12	66.0	76.0	-10.0
Placebo		Week 12	66.0	70.0	-4.0
Placebo		Week 16	62.0	62.0	0.0
Placebo		Week 16	72.0	76.0	-4.0
Placebo		Week 16	70.0	70.0	0.0
Placebo		Week 2	68.0	62.0	6.0
Placebo		Week 2	66.0	76.0	-10.0
Placebo		Week 2	68.0	70.0	-2.0
Placebo		Week 20	70.0	62.0	8.0
Placebo		Week 20	72.0	76.0	-4.0
Placebo		Week 20	74.0	70.0	4.0
Placebo		Week 24	70.0	62.0	8.0
Placebo		Week 24	60.0	76.0	-16.0
Placebo		Week 24	66.0	70.0	-4.0
Placebo		Week 26	60.0	62.0	-2.0
Placebo		Week 26	60.0	76.0	-16.0
Placebo		Week 26	60.0	70.0	-10.0
Placebo		Week 4	64.0	62.0	2.0
Placebo		Week 4	68.0	76.0	-8.0
Placebo		Week 4	68.0	70.0	-2.0
Placebo		Week 6	66.0	62.0	4.0
Placebo		Week 6	68.0	76.0	-8.0
Placebo		Week 6	70.0	70.0	0.0
Placebo		Week 8	66.0	62.0	4.0
Placebo		Week 8	68.0	76.0	-8.0
Placebo		Week 8	66.0	70.0	-4.0
Placebo			70.0	62.0
Placebo			66.0	76.0
Placebo			70.0	70.0
Placebo			66.0	62.0
Placebo			66.0	76.0
Placebo			68.0	70.0
Xanomeline Low Dose		Week 12	82.0	82.0	0.0
Xanomeline Low Dose		Week 12	82.0	86.0	-4.0
Xanomeline Low Dose		Week 12	82.0	80.0	2.0
Xanomeline Low Dose		Week 16	82.0	82.0	0.0
Xanomeline Low Dose		Week 16	82.0	86.0	-4.0
Xanomeline Low Dose		Week 16	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	86.0	82.0	4.0
Xanomeline Low Dose		Week 2	82.0	86.0	-4.0
Xanomeline Low Dose		Week 2	84.0	80.0	4.0
Xanomeline Low Dose		Week 20	78.0	82.0	-4.0
Xanomeline Low Dose		Week 20	84.0	86.0	-2.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 24	80.0	82.0	-2.0
Xanomeline Low Dose		Week 24	80.0	86.0	-6.0
Xanomeline Low Dose		Week 24	80.0	80.0	0.0
Xanomeline Low Dose		Week 26	90.0	82.0	8.0
Xanomeline Low Dose		Week 26	84.0	86.0	-2.0
Xanomeline Low Dose		Week 26	82.0	80.0	2.0
Xanomeline Low Dose		Week 4	88.0	82.0	6.0
Xanomeline Low Dose		Week 4	90.0	86.0	4.0
Xanomeline Low Dose		Week 4	86.0	80.0	6.0
Xanomeline Low Dose		Week 6	80.0	82.0	-2.0
Xanomeline Low Dose		Week 6	84.0	86.0	-2.0
Xanomeline Low Dose		Week 6	84.0	80.0	4.0
Xanomeline Low Dose		Week 8	82.0	82.0	0.0
Xanomeline Low Dose		Week 8	80.0	86.0	-6.0
Xanomeline Low Dose		Week 8	82.0	80.0	2.0
Xanomeline Low Dose			86.0	82.0
Xanomeline Low Dose			86.0	86.0
Xanomeline Low Dose			84.0	80.0
Xanomeline Low Dose			86.0	82.0
Xanomeline Low Dose			90.0	86.0
Xanomeline Low Dose			86.0	80.0
Placebo		Week 2	82.0	82.0	0.0
Placebo		Week 2	76.0	86.0	-10.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo			80.0	82.0
Placebo			80.0	86.0
Placebo			80.0	80.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 2	76.0	66.0	10.0
Xanomeline High Dose		Week 2	76.0	68.0	8.0
Xanomeline High Dose		Week 4	82.0	68.0	14.0
Xanomeline High Dose		Week 4	78.0	66.0	12.0
Xanomeline High Dose		Week 4	80.0	68.0	12.0
Xanomeline High Dose		Week 6	80.0	68.0	12.0
Xanomeline High Dose		Week 6	84.0	66.0	18.0
Xanomeline High Dose		Week 6	80.0	68.0	12.0
Xanomeline High Dose			74.0	68.0
Xanomeline High Dose			70.0	66.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			86.0	68.0
Xanomeline High Dose			82.0	66.0
Xanomeline High Dose			82.0	68.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	74.0	76.0	-2.0
Placebo		Week 2	74.0	68.0	6.0
Placebo		Week 4	74.0	80.0	-6.0
Placebo		Week 4	70.0	76.0	-6.0
Placebo		Week 4	74.0	68.0	6.0
Placebo		Week 6	82.0	80.0	2.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 6	72.0	68.0	4.0
Placebo		Week 8	86.0	80.0	6.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo		Week 8	70.0	68.0	2.0
Placebo			80.0	80.0
Placebo			80.0	76.0
Placebo			76.0	68.0
Placebo			74.0	80.0
Placebo			66.0	76.0
Placebo			68.0	68.0
Xanomeline High Dose		Week 2	76.0	72.0	4.0
Xanomeline High Dose		Week 2	70.0	64.0	6.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 4	72.0	64.0	8.0
Xanomeline High Dose		Week 4	74.0	72.0	2.0
Xanomeline High Dose		Week 6	72.0	72.0	0.0
Xanomeline High Dose		Week 6	78.0	64.0	14.0
Xanomeline High Dose		Week 6	76.0	72.0	4.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 8	84.0	64.0	20.0
Xanomeline High Dose		Week 8	78.0	72.0	6.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			74.0	64.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			76.0	72.0
Xanomeline High Dose			70.0	64.0
Xanomeline High Dose			76.0	72.0
Xanomeline Low Dose		Week 2	70.0	74.0	-4.0
Xanomeline Low Dose		Week 2	82.0	82.0	0.0
Xanomeline Low Dose		Week 2	82.0	76.0	6.0
Xanomeline Low Dose		Week 4	70.0	74.0	-4.0
Xanomeline Low Dose		Week 4	66.0	82.0	-16.0
Xanomeline Low Dose		Week 4	76.0	76.0	0.0
Xanomeline Low Dose			80.0	74.0
Xanomeline Low Dose			84.0	82.0
Xanomeline Low Dose			84.0	76.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	68.0	78.0	-10.0
Xanomeline Low Dose		Week 2	68.0	80.0	-12.0
Xanomeline Low Dose		Week 4	62.0	60.0	2.0
Xanomeline Low Dose		Week 4	68.0	78.0	-10.0
Xanomeline Low Dose		Week 4	68.0	80.0	-12.0
Xanomeline Low Dose		Week 6	68.0	60.0	8.0
Xanomeline Low Dose		Week 6	70.0	78.0	-8.0
Xanomeline Low Dose		Week 6	70.0	80.0	-10.0
Xanomeline Low Dose		Week 8	70.0	60.0	10.0
Xanomeline Low Dose		Week 8	72.0	78.0	-6.0
Xanomeline Low Dose		Week 8	74.0	80.0	-6.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			76.0	78.0
Xanomeline Low Dose			84.0	80.0
Xanomeline Low Dose			66.0	60.0
Xanomeline Low Dose			68.0	78.0
Xanomeline Low Dose			68.0	80.0
Xanomeline High Dose		Week 2	76.0	82.0	-6.0
Xanomeline High Dose		Week 2	80.0	86.0	-6.0
Xanomeline High Dose		Week 2	76.0	86.0	-10.0
Xanomeline High Dose		Week 4	66.0	82.0	-16.0
Xanomeline High Dose		Week 4	82.0	86.0	-4.0
Xanomeline High Dose		Week 4	82.0	86.0	-4.0
Xanomeline High Dose		Week 6	78.0	82.0	-4.0
Xanomeline High Dose		Week 6	80.0	86.0	-6.0
Xanomeline High Dose		Week 6	82.0	86.0	-4.0
Xanomeline High Dose		Week 8	76.0	82.0	-6.0
Xanomeline High Dose		Week 8	74.0	86.0	-12.0
Xanomeline High Dose		Week 8	72.0	86.0	-14.0
Xanomeline High Dose			80.0	82.0
Xanomeline High Dose			78.0	86.0
Xanomeline High Dose			78.0	86.0
Xanomeline High Dose			68.0	82.0
Xanomeline High Dose			80.0	86.0
Xanomeline High Dose			78.0	86.0
Placebo		Week 12	74.0	78.0	-4.0
Placebo		Week 12	86.0	82.0	4.0
Placebo		Week 12	82.0	80.0	2.0
Placebo		Week 16	70.0	78.0	-8.0
Placebo		Week 16	85.0	82.0	3.0
Placebo		Week 16	68.0	80.0	-12.0
Placebo		Week 2	76.0	78.0	-2.0
Placebo		Week 2	84.0	82.0	2.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 20	70.0	78.0	-8.0
Placebo		Week 20	85.0	82.0	3.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 24	68.0	78.0	-10.0
Placebo		Week 24	78.0	82.0	-4.0
Placebo		Week 24	68.0	80.0	-12.0
Placebo		Week 26	74.0	78.0	-4.0
Placebo		Week 26	78.0	82.0	-4.0
Placebo		Week 26	74.0	80.0	-6.0
Placebo		Week 4	68.0	78.0	-10.0
Placebo		Week 4	68.0	82.0	-14.0
Placebo		Week 4	64.0	80.0	-16.0
Placebo		Week 6	72.0	78.0	-6.0
Placebo		Week 6	68.0	82.0	-14.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 8	76.0	78.0	-2.0
Placebo		Week 8	80.0	82.0	-2.0
Placebo		Week 8	82.0	80.0	2.0
Placebo			72.0	78.0
Placebo			74.0	82.0
Placebo			70.0	80.0
Placebo		Week 12	74.0	84.0	-10.0
Placebo		Week 12	80.0	74.0	6.0
Placebo		Week 12	82.0	76.0	6.0
Placebo		Week 16	70.0	84.0	-14.0
Placebo		Week 16	78.0	74.0	4.0
Placebo		Week 16	80.0	76.0	4.0
Placebo		Week 2	76.0	84.0	-8.0
Placebo		Week 2	74.0	74.0	0.0
Placebo		Week 2	72.0	76.0	-4.0
Placebo		Week 20	74.0	84.0	-10.0
Placebo		Week 20	70.0	74.0	-4.0
Placebo		Week 20	72.0	76.0	-4.0
Placebo		Week 24	68.0	84.0	-16.0
Placebo		Week 24	70.0	74.0	-4.0
Placebo		Week 24	64.0	76.0	-12.0
Placebo		Week 4	80.0	84.0	-4.0
Placebo		Week 4	76.0	74.0	2.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 6	78.0	84.0	-6.0
Placebo		Week 6	72.0	74.0	-2.0
Placebo		Week 6	76.0	76.0	0.0
Placebo		Week 8	80.0	84.0	-4.0
Placebo		Week 8	76.0	74.0	2.0
Placebo		Week 8	76.0	76.0	0.0
Placebo			78.0	84.0
Placebo			80.0	74.0
Placebo			78.0	76.0
Placebo			78.0	84.0
Placebo			74.0	74.0
Placebo			76.0	76.0
Placebo		Week 2	68.0	84.0	-16.0
Placebo		Week 2	62.0	74.0	-12.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 4	76.0	84.0	-8.0
Placebo		Week 4	78.0	74.0	4.0
Placebo		Week 4	74.0	72.0	2.0
Placebo		Week 6	70.0	84.0	-14.0
Placebo		Week 6	68.0	74.0	-6.0
Placebo		Week 6	70.0	72.0	-2.0
Placebo			86.0	84.0
Placebo			80.0	74.0
Placebo			82.0	72.0
Placebo			68.0	84.0
Placebo			60.0	74.0
Placebo			64.0	72.0
Placebo		Week 12	68.0	72.0	-4.0
Placebo		Week 12	78.0	76.0	2.0
Placebo		Week 12	74.0	78.0	-4.0
Placebo		Week 16	82.0	72.0	10.0
Placebo		Week 16	84.0	76.0	8.0
Placebo		Week 16	88.0	78.0	10.0
Placebo		Week 2	74.0	72.0	2.0
Placebo		Week 2	78.0	76.0	2.0
Placebo		Week 2	76.0	78.0	-2.0
Placebo		Week 20	84.0	72.0	12.0
Placebo		Week 20	82.0	76.0	6.0
Placebo		Week 20	68.0	78.0	-10.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	76.0	78.0	-2.0
Placebo		Week 6	70.0	72.0	-2.0
Placebo		Week 6	74.0	76.0	-2.0
Placebo		Week 6	76.0	78.0	-2.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	74.0	76.0	-2.0
Placebo		Week 8	78.0	78.0	0.0
Placebo			74.0	72.0
Placebo			76.0	76.0
Placebo			78.0	78.0
Placebo			70.0	72.0
Placebo			76.0	76.0
Placebo			78.0	78.0
Xanomeline Low Dose		Week 2	80.0	84.0	-4.0
Xanomeline Low Dose		Week 2	70.0	86.0	-16.0
Xanomeline Low Dose		Week 2	70.0	84.0	-14.0
Xanomeline Low Dose			80.0	84.0
Xanomeline Low Dose			70.0	86.0
Xanomeline Low Dose			70.0	84.0
Placebo		Week 12	88.0	95.0	-7.0
Placebo		Week 12	84.0	94.0	-10.0
Placebo		Week 12	84.0	94.0	-10.0
Placebo		Week 16	80.0	95.0	-15.0
Placebo		Week 16	80.0	94.0	-14.0
Placebo		Week 16	80.0	94.0	-14.0
Placebo		Week 2	75.0	95.0	-20.0
Placebo		Week 2	75.0	94.0	-19.0
Placebo		Week 2	75.0	94.0	-19.0
Placebo		Week 4	80.0	95.0	-15.0
Placebo		Week 4	78.0	94.0	-16.0
Placebo		Week 4	80.0	94.0	-14.0
Placebo		Week 6	90.0	95.0	-5.0
Placebo		Week 6	80.0	94.0	-14.0
Placebo		Week 6	75.0	94.0	-19.0
Placebo		Week 8	80.0	95.0	-15.0
Placebo		Week 8	80.0	94.0	-14.0
Placebo		Week 8	80.0	94.0	-14.0
Placebo			85.0	95.0
Placebo			80.0	94.0
Placebo			82.0	94.0
Placebo			80.0	95.0
Placebo			80.0	94.0
Placebo			80.0	94.0
Placebo		Week 2	75.0	70.0	5.0
Placebo		Week 2	65.0	70.0	-5.0
Placebo		Week 2	70.0	70.0	0.0
Placebo			70.0	70.0
Placebo			64.0	70.0
Placebo			74.0	70.0
Xanomeline High Dose		Week 12	90.0	70.0	20.0
Xanomeline High Dose		Week 12	88.0	70.0	18.0
Xanomeline High Dose		Week 12	88.0	70.0	18.0
Xanomeline High Dose		Week 16	92.0	70.0	22.0
Xanomeline High Dose		Week 16	88.0	70.0	18.0
Xanomeline High Dose		Week 16	82.0	70.0	12.0
Xanomeline High Dose		Week 2	84.0	70.0	14.0
Xanomeline High Dose		Week 2	84.0	70.0	14.0
Xanomeline High Dose		Week 2	88.0	70.0	18.0
Xanomeline High Dose		Week 20	98.0	70.0	28.0
Xanomeline High Dose		Week 20	90.0	70.0	20.0
Xanomeline High Dose		Week 20	90.0	70.0	20.0
Xanomeline High Dose		Week 24	84.0	70.0	14.0
Xanomeline High Dose		Week 24	82.0	70.0	12.0
Xanomeline High Dose		Week 24	82.0	70.0	12.0
Xanomeline High Dose		Week 26	90.0	70.0	20.0
Xanomeline High Dose		Week 26	90.0	70.0	20.0
Xanomeline High Dose		Week 26	90.0	70.0	20.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 6	86.0	70.0	16.0
Xanomeline High Dose		Week 6	80.0	70.0	10.0
Xanomeline High Dose		Week 6	88.0	70.0	18.0
Xanomeline High Dose		Week 8	88.0	70.0	18.0
Xanomeline High Dose		Week 8	84.0	70.0	14.0
Xanomeline High Dose		Week 8	88.0	70.0	18.0
Xanomeline High Dose			60.0	70.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			90.0	70.0
Xanomeline High Dose			85.0	70.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	88.0	80.0	8.0
Xanomeline High Dose		Week 12	88.0	80.0	8.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 4	85.0	80.0	5.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 4	85.0	80.0	5.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 6	85.0	80.0	5.0
Xanomeline High Dose		Week 8	90.0	80.0	10.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose			85.0	80.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	80.0
Placebo		Week 12	80.0	70.0	10.0
Placebo		Week 12	88.0	80.0	8.0
Placebo		Week 12	88.0	80.0	8.0
Placebo		Week 16	75.0	70.0	5.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 2	84.0	70.0	14.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 20	84.0	70.0	14.0
Placebo		Week 20	80.0	80.0	0.0
Placebo		Week 20	80.0	80.0	0.0
Placebo		Week 24	80.0	70.0	10.0
Placebo		Week 24	78.0	80.0	-2.0
Placebo		Week 24	78.0	80.0	-2.0
Placebo		Week 26	80.0	70.0	10.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 4	75.0	70.0	5.0
Placebo		Week 4	75.0	80.0	-5.0
Placebo		Week 4	75.0	80.0	-5.0
Placebo		Week 6	80.0	70.0	10.0
Placebo		Week 6	70.0	80.0	-10.0
Placebo		Week 6	70.0	80.0	-10.0
Placebo		Week 8	80.0	70.0	10.0
Placebo		Week 8	85.0	80.0	5.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			85.0	70.0
Placebo			80.0	80.0
Placebo			80.0	80.0
Placebo			84.0	70.0
Placebo			80.0	80.0
Placebo			80.0	80.0
Xanomeline Low Dose		Week 12	86.0	80.0	6.0
Xanomeline Low Dose		Week 12	90.0	80.0	10.0
Xanomeline Low Dose		Week 12	90.0	80.0	10.0
Xanomeline Low Dose		Week 16	90.0	80.0	10.0
Xanomeline Low Dose		Week 16	90.0	80.0	10.0
Xanomeline Low Dose		Week 16	90.0	80.0	10.0
Xanomeline Low Dose		Week 2	86.0	80.0	6.0
Xanomeline Low Dose		Week 2	84.0	80.0	4.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 20	90.0	80.0	10.0
Xanomeline Low Dose		Week 20	90.0	80.0	10.0
Xanomeline Low Dose		Week 20	90.0	80.0	10.0
Xanomeline Low Dose		Week 24	90.0	80.0	10.0
Xanomeline Low Dose		Week 24	90.0	80.0	10.0
Xanomeline Low Dose		Week 24	90.0	80.0	10.0
Xanomeline Low Dose		Week 4	82.0	80.0	2.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	85.0	80.0	5.0
Xanomeline Low Dose		Week 8	95.0	80.0	15.0
Xanomeline Low Dose		Week 8	95.0	80.0	15.0
Xanomeline Low Dose			88.0	80.0
Xanomeline Low Dose			85.0	80.0
Xanomeline Low Dose			85.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline High Dose		Week 2	84.0	90.0	-6.0
Xanomeline High Dose		Week 2	80.0	90.0	-10.0
Xanomeline High Dose		Week 2	80.0	90.0	-10.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose		Week 12	60.0	84.0	-24.0
Xanomeline High Dose		Week 12	60.0	80.0	-20.0
Xanomeline High Dose		Week 12	60.0	80.0	-20.0
Xanomeline High Dose		Week 2	90.0	84.0	6.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 4	80.0	84.0	-4.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 6	85.0	84.0	1.0
Xanomeline High Dose		Week 6	78.0	80.0	-2.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 8	80.0	84.0	-4.0
Xanomeline High Dose		Week 8	70.0	80.0	-10.0
Xanomeline High Dose		Week 8	72.0	80.0	-8.0
Xanomeline High Dose			70.0	84.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			86.0	84.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	80.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 20	74.0	80.0	-6.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 24	70.0	80.0	-10.0
Placebo		Week 24	65.0	80.0	-15.0
Placebo		Week 24	65.0	80.0	-15.0
Placebo		Week 26	70.0	80.0	-10.0
Placebo		Week 26	70.0	80.0	-10.0
Placebo		Week 26	70.0	80.0	-10.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 6	60.0	80.0	-20.0
Placebo		Week 6	60.0	80.0	-20.0
Placebo		Week 6	68.0	80.0	-12.0
Placebo		Week 8	75.0	80.0	-5.0
Placebo		Week 8	75.0	80.0	-5.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo			70.0	80.0
Placebo			68.0	80.0
Placebo			67.0	80.0
Xanomeline High Dose		Week 2	70.0	64.0	6.0
Xanomeline High Dose		Week 2	70.0	70.0	0.0
Xanomeline High Dose		Week 2	70.0	68.0	2.0
Xanomeline High Dose			80.0	64.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	68.0
Xanomeline Low Dose		Week 12	100.0	90.0	10.0
Xanomeline Low Dose		Week 12	96.0	90.0	6.0
Xanomeline Low Dose		Week 12	98.0	90.0	8.0
Xanomeline Low Dose		Week 16	90.0	90.0	0.0
Xanomeline Low Dose		Week 16	84.0	90.0	-6.0
Xanomeline Low Dose		Week 16	84.0	90.0	-6.0
Xanomeline Low Dose		Week 2	80.0	90.0	-10.0
Xanomeline Low Dose		Week 2	70.0	90.0	-20.0
Xanomeline Low Dose		Week 2	70.0	90.0	-20.0
Xanomeline Low Dose		Week 4	80.0	90.0	-10.0
Xanomeline Low Dose		Week 4	85.0	90.0	-5.0
Xanomeline Low Dose		Week 4	80.0	90.0	-10.0
Xanomeline Low Dose		Week 6	90.0	90.0	0.0
Xanomeline Low Dose		Week 6	80.0	90.0	-10.0
Xanomeline Low Dose		Week 6	70.0	90.0	-20.0
Xanomeline Low Dose		Week 8	70.0	90.0	-20.0
Xanomeline Low Dose		Week 8	60.0	90.0	-30.0
Xanomeline Low Dose		Week 8	60.0	90.0	-30.0
Xanomeline Low Dose			98.0	90.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			95.0	90.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose		Week 12	60.0	80.0	-20.0
Xanomeline Low Dose		Week 12	60.0	80.0	-20.0
Xanomeline Low Dose		Week 12	55.0	80.0	-25.0
Xanomeline Low Dose		Week 16	70.0	80.0	-10.0
Xanomeline Low Dose		Week 16	70.0	80.0	-10.0
Xanomeline Low Dose		Week 16	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	82.0	80.0	2.0
Xanomeline Low Dose		Week 2	78.0	80.0	-2.0
Xanomeline Low Dose		Week 2	78.0	80.0	-2.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 24	60.0	80.0	-20.0
Xanomeline Low Dose		Week 24	60.0	80.0	-20.0
Xanomeline Low Dose		Week 24	60.0	80.0	-20.0
Xanomeline Low Dose		Week 26	65.0	80.0	-15.0
Xanomeline Low Dose		Week 26	60.0	80.0	-20.0
Xanomeline Low Dose		Week 26	60.0	80.0	-20.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	72.0	80.0	-8.0
Xanomeline Low Dose		Week 4	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	82.0	80.0	2.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	76.0	80.0	-4.0
Xanomeline Low Dose		Week 8	55.0	80.0	-25.0
Xanomeline Low Dose		Week 8	60.0	80.0	-20.0
Xanomeline Low Dose		Week 8	60.0	80.0	-20.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	80.0
Placebo		Week 12	84.0	80.0	4.0
Placebo		Week 12	88.0	78.0	10.0
Placebo		Week 12	79.0	80.0	-1.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 16	92.0	78.0	14.0
Placebo		Week 16	86.0	80.0	6.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	80.0	78.0	2.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 20	84.0	80.0	4.0
Placebo		Week 20	88.0	78.0	10.0
Placebo		Week 20	88.0	80.0	8.0
Placebo		Week 24	74.0	80.0	-6.0
Placebo		Week 24	88.0	78.0	10.0
Placebo		Week 24	94.0	80.0	14.0
Placebo		Week 4	90.0	80.0	10.0
Placebo		Week 4	92.0	78.0	14.0
Placebo		Week 4	92.0	80.0	12.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	80.0	78.0	2.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	80.0	78.0	2.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			80.0	80.0
Placebo			80.0	78.0
Placebo			80.0	80.0
Placebo			90.0	80.0
Placebo			88.0	78.0
Placebo			90.0	80.0
Xanomeline High Dose		Week 2	70.0	80.0	-10.0
Xanomeline High Dose		Week 2	70.0	78.0	-8.0
Xanomeline High Dose		Week 2	70.0	78.0	-8.0
Xanomeline High Dose		Week 4	78.0	80.0	-2.0
Xanomeline High Dose		Week 4	70.0	78.0	-8.0
Xanomeline High Dose		Week 4	74.0	78.0	-4.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			74.0	78.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose			72.0	78.0
Placebo		Week 12	80.0	84.0	-4.0
Placebo		Week 12	84.0	84.0	0.0
Placebo		Week 12	86.0	80.0	6.0
Placebo		Week 16	78.0	84.0	-6.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 16	86.0	80.0	6.0
Placebo		Week 2	70.0	84.0	-14.0
Placebo		Week 2	68.0	84.0	-16.0
Placebo		Week 2	68.0	80.0	-12.0
Placebo		Week 20	70.0	84.0	-14.0
Placebo		Week 20	60.0	84.0	-24.0
Placebo		Week 20	66.0	80.0	-14.0
Placebo		Week 24	82.0	84.0	-2.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 24	78.0	80.0	-2.0
Placebo		Week 4	68.0	84.0	-16.0
Placebo		Week 4	70.0	84.0	-14.0
Placebo		Week 4	66.0	80.0	-14.0
Placebo		Week 6	86.0	84.0	2.0
Placebo		Week 6	84.0	84.0	0.0
Placebo		Week 6	86.0	80.0	6.0
Placebo		Week 8	82.0	84.0	-2.0
Placebo		Week 8	80.0	84.0	-4.0
Placebo		Week 8	82.0	80.0	2.0
Placebo			68.0	84.0
Placebo			70.0	84.0
Placebo			70.0	80.0
Placebo			70.0	84.0
Placebo			64.0	84.0
Placebo			70.0	80.0
Xanomeline Low Dose		Week 2	86.0	80.0	6.0
Xanomeline Low Dose		Week 2	88.0	98.0	-10.0
Xanomeline Low Dose		Week 2	92.0	108.0	-16.0
Xanomeline Low Dose			90.0	80.0
Xanomeline Low Dose			95.0	98.0
Xanomeline Low Dose			96.0	108.0
Xanomeline Low Dose		Week 12	60.0	70.0	-10.0
Xanomeline Low Dose		Week 12	60.0	60.0	0.0
Xanomeline Low Dose		Week 12	68.0	80.0	-12.0
Xanomeline Low Dose		Week 16	60.0	70.0	-10.0
Xanomeline Low Dose		Week 16	60.0	60.0	0.0
Xanomeline Low Dose		Week 16	60.0	80.0	-20.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 2	70.0	60.0	10.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	68.0	70.0	-2.0
Xanomeline Low Dose		Week 20	78.0	60.0	18.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 24	60.0	70.0	-10.0
Xanomeline Low Dose		Week 24	60.0	60.0	0.0
Xanomeline Low Dose		Week 24	60.0	80.0	-20.0
Xanomeline Low Dose		Week 26	62.0	70.0	-8.0
Xanomeline Low Dose		Week 26	76.0	60.0	16.0
Xanomeline Low Dose		Week 26	70.0	80.0	-10.0
Xanomeline Low Dose		Week 4	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	80.0	60.0	20.0
Xanomeline Low Dose		Week 4	76.0	80.0	-4.0
Xanomeline Low Dose		Week 6	64.0	70.0	-6.0
Xanomeline Low Dose		Week 6	84.0	60.0	24.0
Xanomeline Low Dose		Week 6	72.0	80.0	-8.0
Xanomeline Low Dose		Week 8	70.0	70.0	0.0
Xanomeline Low Dose		Week 8	70.0	60.0	10.0
Xanomeline Low Dose		Week 8	68.0	80.0	-12.0
Xanomeline Low Dose			58.0	70.0
Xanomeline Low Dose			70.0	60.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			50.0	60.0
Xanomeline Low Dose			60.0	80.0
Placebo		Week 12	80.0	76.0	4.0
Placebo		Week 12	80.0	68.0	12.0
Placebo		Week 12	80.0	70.0	10.0
Placebo		Week 16	86.0	76.0	10.0
Placebo		Week 16	78.0	68.0	10.0
Placebo		Week 16	84.0	70.0	14.0
Placebo		Week 2	78.0	76.0	2.0
Placebo		Week 2	70.0	68.0	2.0
Placebo		Week 2	78.0	70.0	8.0
Placebo		Week 20	80.0	76.0	4.0
Placebo		Week 20	78.0	68.0	10.0
Placebo		Week 20	80.0	70.0	10.0
Placebo		Week 24	80.0	76.0	4.0
Placebo		Week 24	80.0	68.0	12.0
Placebo		Week 24	82.0	70.0	12.0
Placebo		Week 26	68.0	76.0	-8.0
Placebo		Week 26	68.0	68.0	0.0
Placebo		Week 26	70.0	70.0	0.0
Placebo		Week 4	72.0	76.0	-4.0
Placebo		Week 4	80.0	68.0	12.0
Placebo		Week 4	78.0	70.0	8.0
Placebo		Week 6	78.0	76.0	2.0
Placebo		Week 6	74.0	68.0	6.0
Placebo		Week 6	78.0	70.0	8.0
Placebo		Week 8	80.0	76.0	4.0
Placebo		Week 8	70.0	68.0	2.0
Placebo		Week 8	90.0	70.0	20.0
Placebo			80.0	76.0
Placebo			78.0	68.0
Placebo			80.0	70.0
Placebo		Week 2	78.0	76.0	2.0
Placebo		Week 2	70.0	70.0	0.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 4	84.0	76.0	8.0
Placebo		Week 4	88.0	70.0	18.0
Placebo		Week 4	88.0	80.0	8.0
Placebo			82.0	76.0
Placebo			80.0	70.0
Placebo			80.0	80.0
Placebo			80.0	76.0
Placebo			75.0	70.0
Placebo			80.0	80.0
Placebo		Week 12	60.0	70.0	-10.0
Placebo		Week 12	64.0	70.0	-6.0
Placebo		Week 12	68.0	70.0	-2.0
Placebo		Week 16	64.0	70.0	-6.0
Placebo		Week 16	70.0	70.0	0.0
Placebo		Week 16	70.0	70.0	0.0
Placebo		Week 2	84.0	70.0	14.0
Placebo		Week 2	78.0	70.0	8.0
Placebo		Week 2	76.0	70.0	6.0
Placebo		Week 20	60.0	70.0	-10.0
Placebo		Week 20	58.0	70.0	-12.0
Placebo		Week 20	60.0	70.0	-10.0
Placebo		Week 24	60.0	70.0	-10.0
Placebo		Week 24	60.0	70.0	-10.0
Placebo		Week 24	64.0	70.0	-6.0
Placebo		Week 26	74.0	70.0	4.0
Placebo		Week 26	72.0	70.0	2.0
Placebo		Week 26	78.0	70.0	8.0
Placebo		Week 4	80.0	70.0	10.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 4	80.0	70.0	10.0
Placebo		Week 6	60.0	70.0	-10.0
Placebo		Week 6	64.0	70.0	-6.0
Placebo		Week 6	72.0	70.0	2.0
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	70.0	70.0	0.0
Placebo			68.0	70.0
Placebo			70.0	70.0
Placebo			72.0	70.0
Placebo			80.0	70.0
Placebo			78.0	70.0
Placebo			78.0	70.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	76.0	92.0	-16.0
Xanomeline High Dose		Week 2	74.0	78.0	-4.0
Xanomeline High Dose		Week 2	80.0	78.0	2.0
Xanomeline High Dose		Week 2	82.0	92.0	-10.0
Xanomeline High Dose		Week 4	82.0	78.0	4.0
Xanomeline High Dose		Week 4	90.0	78.0	12.0
Xanomeline High Dose		Week 4	80.0	92.0	-12.0
Xanomeline High Dose		Week 6	80.0	78.0	2.0
Xanomeline High Dose		Week 6	75.0	78.0	-3.0
Xanomeline High Dose		Week 6	75.0	92.0	-17.0
Xanomeline High Dose		Week 8	78.0	78.0	0.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose		Week 8	84.0	92.0	-8.0
Xanomeline High Dose			80.0	78.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose			76.0	92.0
Xanomeline High Dose			84.0	78.0
Xanomeline High Dose			98.0	78.0
Xanomeline High Dose			98.0	92.0
Xanomeline Low Dose		Week 2	80.0	68.0	12.0
Xanomeline Low Dose		Week 2	94.0	88.0	6.0
Xanomeline Low Dose		Week 2	88.0	88.0	0.0
Xanomeline High Dose		Week 2	70.0	80.0	-10.0
Xanomeline High Dose		Week 2	70.0	94.0	-24.0
Xanomeline High Dose		Week 2	70.0	100.0	-30.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 4	70.0	94.0	-24.0
Xanomeline High Dose		Week 4	70.0	100.0	-30.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			76.0	94.0
Xanomeline High Dose			70.0	100.0
Xanomeline High Dose			78.0	80.0
Xanomeline High Dose			70.0	94.0
Xanomeline High Dose			80.0	100.0
Placebo		Week 12	90.0	86.0	4.0
Placebo		Week 12	100.0	98.0	2.0
Placebo		Week 12	104.0	98.0	6.0
Placebo		Week 16	86.0	86.0	0.0
Placebo		Week 16	96.0	98.0	-2.0
Placebo		Week 16	98.0	98.0	0.0
Placebo		Week 2	84.0	86.0	-2.0
Placebo		Week 2	90.0	98.0	-8.0
Placebo		Week 2	100.0	98.0	2.0
Placebo		Week 20	80.0	86.0	-6.0
Placebo		Week 20	82.0	98.0	-16.0
Placebo		Week 20	80.0	98.0	-18.0
Placebo		Week 24	80.0	86.0	-6.0
Placebo		Week 24	78.0	98.0	-20.0
Placebo		Week 24	76.0	98.0	-22.0
Placebo		Week 26	70.0	86.0	-16.0
Placebo		Week 26	78.0	98.0	-20.0
Placebo		Week 26	82.0	98.0	-16.0
Placebo		Week 4	90.0	86.0	4.0
Placebo		Week 4	98.0	98.0	0.0
Placebo		Week 4	98.0	98.0	0.0
Placebo		Week 6	80.0	86.0	-6.0
Placebo		Week 6	70.0	98.0	-28.0
Placebo		Week 6	72.0	98.0	-26.0
Placebo		Week 8	78.0	86.0	-8.0
Placebo		Week 8	80.0	98.0	-18.0
Placebo		Week 8	70.0	98.0	-28.0
Placebo			70.0	86.0
Placebo			90.0	98.0
Placebo			100.0	98.0
Placebo			94.0	86.0
Placebo			100.0	98.0
Placebo			100.0	98.0
Xanomeline Low Dose		Week 2	80.0	72.0	8.0
Xanomeline Low Dose		Week 2	70.0	82.0	-12.0
Xanomeline Low Dose		Week 2	80.0	84.0	-4.0
Xanomeline Low Dose		Week 4	86.0	72.0	14.0
Xanomeline Low Dose		Week 4	80.0	82.0	-2.0
Xanomeline Low Dose		Week 4	84.0	84.0	0.0
Xanomeline Low Dose		Week 6	80.0	72.0	8.0
Xanomeline Low Dose		Week 6	80.0	82.0	-2.0
Xanomeline Low Dose		Week 6	90.0	84.0	6.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			60.0	82.0
Xanomeline Low Dose			60.0	84.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			60.0	82.0
Xanomeline Low Dose			68.0	84.0
Placebo		Week 12	68.0	72.0	-4.0
Placebo		Week 12	60.0	80.0	-20.0
Placebo		Week 12	74.0	80.0	-6.0
Placebo		Week 16	84.0	72.0	12.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	84.0	80.0	4.0
Placebo		Week 2	78.0	72.0	6.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	84.0	80.0	4.0
Placebo		Week 20	74.0	72.0	2.0
Placebo		Week 20	90.0	80.0	10.0
Placebo		Week 20	90.0	80.0	10.0
Placebo		Week 24	60.0	72.0	-12.0
Placebo		Week 24	68.0	80.0	-12.0
Placebo		Week 24	60.0	80.0	-20.0
Placebo		Week 26	80.0	72.0	8.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 26	82.0	80.0	2.0
Placebo		Week 4	88.0	72.0	16.0
Placebo		Week 4	90.0	80.0	10.0
Placebo		Week 4	98.0	80.0	18.0
Placebo		Week 6	78.0	72.0	6.0
Placebo		Week 6	74.0	80.0	-6.0
Placebo		Week 6	78.0	80.0	-2.0
Placebo		Week 8	80.0	72.0	8.0
Placebo		Week 8	78.0	80.0	-2.0
Placebo		Week 8	72.0	80.0	-8.0
Placebo			82.0	72.0
Placebo			82.0	80.0
Placebo			84.0	80.0
Placebo			80.0	72.0
Placebo			82.0	80.0
Placebo			90.0	80.0
Placebo		Week 12	88.0	80.0	8.0
Placebo		Week 12	90.0	82.0	8.0
Placebo		Week 12	98.0	102.0	-4.0
Placebo		Week 16	82.0	80.0	2.0
Placebo		Week 16	84.0	82.0	2.0
Placebo		Week 16	90.0	102.0	-12.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	70.0	82.0	-12.0
Placebo		Week 2	76.0	102.0	-26.0
Placebo		Week 20	84.0	80.0	4.0
Placebo		Week 20	88.0	82.0	6.0
Placebo		Week 20	88.0	102.0	-14.0
Placebo		Week 24	84.0	80.0	4.0
Placebo		Week 24	90.0	82.0	8.0
Placebo		Week 24	90.0	102.0	-12.0
Placebo		Week 26	90.0	80.0	10.0
Placebo		Week 26	98.0	82.0	16.0
Placebo		Week 26	98.0	102.0	-4.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	88.0	82.0	6.0
Placebo		Week 4	88.0	102.0	-14.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	72.0	82.0	-10.0
Placebo		Week 6	80.0	102.0	-22.0
Placebo		Week 8	78.0	80.0	-2.0
Placebo		Week 8	76.0	82.0	-6.0
Placebo		Week 8	78.0	102.0	-24.0
Placebo			90.0	80.0
Placebo			90.0	82.0
Placebo			98.0	102.0
Placebo			82.0	80.0
Placebo			82.0	82.0
Placebo			80.0	102.0
Xanomeline Low Dose		Week 12	80.0	80.0	0.0
Xanomeline Low Dose		Week 12	78.0	80.0	-2.0
Xanomeline Low Dose		Week 12	84.0	80.0	4.0
Xanomeline Low Dose		Week 2	68.0	80.0	-12.0
Xanomeline Low Dose		Week 2	90.0	80.0	10.0
Xanomeline Low Dose		Week 2	90.0	80.0	10.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	74.0	80.0	-6.0
Xanomeline Low Dose		Week 8	88.0	80.0	8.0
Xanomeline Low Dose		Week 8	84.0	80.0	4.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			78.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			84.0	80.0
Xanomeline Low Dose			88.0	80.0
Placebo		Week 12	68.0	80.0	-12.0
Placebo		Week 12	66.0	80.0	-14.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 16	60.0	80.0	-20.0
Placebo		Week 16	64.0	80.0	-16.0
Placebo		Week 16	60.0	80.0	-20.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 24	84.0	80.0	4.0
Placebo		Week 24	86.0	80.0	6.0
Placebo		Week 26	74.0	80.0	-6.0
Placebo		Week 26	82.0	80.0	2.0
Placebo		Week 26	90.0	80.0	10.0
Placebo		Week 4	66.0	80.0	-14.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 6	52.0	80.0	-28.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	82.0	80.0	2.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	70.0	80.0	-10.0
Xanomeline High Dose		Week 12	74.0	70.0	4.0
Xanomeline High Dose		Week 12	84.0	70.0	14.0
Xanomeline High Dose		Week 12	84.0	68.0	16.0
Xanomeline High Dose		Week 16	78.0	70.0	8.0
Xanomeline High Dose		Week 16	80.0	70.0	10.0
Xanomeline High Dose		Week 16	74.0	68.0	6.0
Xanomeline High Dose		Week 2	80.0	70.0	10.0
Xanomeline High Dose		Week 2	78.0	70.0	8.0
Xanomeline High Dose		Week 2	80.0	68.0	12.0
Xanomeline High Dose		Week 20	82.0	70.0	12.0
Xanomeline High Dose		Week 20	80.0	70.0	10.0
Xanomeline High Dose		Week 20	90.0	68.0	22.0
Xanomeline High Dose		Week 24	80.0	70.0	10.0
Xanomeline High Dose		Week 24	82.0	70.0	12.0
Xanomeline High Dose		Week 24	80.0	68.0	12.0
Xanomeline High Dose		Week 26	78.0	70.0	8.0
Xanomeline High Dose		Week 26	74.0	70.0	4.0
Xanomeline High Dose		Week 26	72.0	68.0	4.0
Xanomeline High Dose		Week 4	94.0	70.0	24.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 4	88.0	68.0	20.0
Xanomeline High Dose		Week 6	70.0	70.0	0.0
Xanomeline High Dose		Week 6	70.0	70.0	0.0
Xanomeline High Dose		Week 6	72.0	68.0	4.0
Xanomeline High Dose		Week 8	78.0	70.0	8.0
Xanomeline High Dose		Week 8	80.0	70.0	10.0
Xanomeline High Dose		Week 8	80.0	68.0	12.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			76.0	68.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	74.0	90.0	-16.0
Placebo		Week 12	80.0	90.0	-10.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	90.0	90.0	0.0
Placebo		Week 16	94.0	90.0	4.0
Placebo		Week 2	88.0	80.0	8.0
Placebo		Week 2	94.0	90.0	4.0
Placebo		Week 2	90.0	90.0	0.0
Placebo		Week 20	60.0	80.0	-20.0
Placebo		Week 20	80.0	90.0	-10.0
Placebo		Week 20	80.0	90.0	-10.0
Placebo		Week 24	90.0	80.0	10.0
Placebo		Week 24	92.0	90.0	2.0
Placebo		Week 24	90.0	90.0	0.0
Placebo		Week 26	82.0	80.0	2.0
Placebo		Week 26	82.0	90.0	-8.0
Placebo		Week 26	76.0	90.0	-14.0
Placebo		Week 4	86.0	80.0	6.0
Placebo		Week 4	98.0	90.0	8.0
Placebo		Week 4	100.0	90.0	10.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 6	100.0	90.0	10.0
Placebo		Week 6	100.0	90.0	10.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	78.0	90.0	-12.0
Placebo		Week 8	78.0	90.0	-12.0
Placebo			88.0	80.0
Placebo			80.0	90.0
Placebo			80.0	90.0
Placebo			80.0	80.0
Placebo			82.0	90.0
Placebo			78.0	90.0
Xanomeline High Dose		Week 12	80.0	88.0	-8.0
Xanomeline High Dose		Week 12	90.0	80.0	10.0
Xanomeline High Dose		Week 12	84.0	78.0	6.0
Xanomeline High Dose		Week 2	80.0	88.0	-8.0
Xanomeline High Dose		Week 2	88.0	80.0	8.0
Xanomeline High Dose		Week 2	92.0	78.0	14.0
Xanomeline High Dose		Week 4	60.0	88.0	-28.0
Xanomeline High Dose		Week 4	62.0	80.0	-18.0
Xanomeline High Dose		Week 4	60.0	78.0	-18.0
Xanomeline High Dose		Week 6	78.0	88.0	-10.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 6	82.0	78.0	4.0
Xanomeline High Dose		Week 8	70.0	88.0	-18.0
Xanomeline High Dose		Week 8	72.0	80.0	-8.0
Xanomeline High Dose		Week 8	70.0	78.0	-8.0
Xanomeline High Dose			90.0	88.0
Xanomeline High Dose			92.0	80.0
Xanomeline High Dose			96.0	78.0
Xanomeline High Dose			82.0	88.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			88.0	78.0
Xanomeline Low Dose		Week 12	82.0	80.0	2.0
Xanomeline Low Dose		Week 12	80.0	60.0	20.0
Xanomeline Low Dose		Week 12	84.0	70.0	14.0
Xanomeline Low Dose		Week 16	72.0	80.0	-8.0
Xanomeline Low Dose		Week 16	80.0	60.0	20.0
Xanomeline Low Dose		Week 16	82.0	70.0	12.0
Xanomeline Low Dose		Week 2	92.0	80.0	12.0
Xanomeline Low Dose		Week 2	65.0	60.0	5.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 20	72.0	60.0	12.0
Xanomeline Low Dose		Week 20	80.0	70.0	10.0
Xanomeline Low Dose		Week 24	76.0	80.0	-4.0
Xanomeline Low Dose		Week 24	78.0	60.0	18.0
Xanomeline Low Dose		Week 24	80.0	70.0	10.0
Xanomeline Low Dose		Week 26	70.0	80.0	-10.0
Xanomeline Low Dose		Week 26	60.0	60.0	0.0
Xanomeline Low Dose		Week 26	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	82.0	80.0	2.0
Xanomeline Low Dose		Week 4	88.0	60.0	28.0
Xanomeline Low Dose		Week 4	80.0	70.0	10.0
Xanomeline Low Dose		Week 6	88.0	80.0	8.0
Xanomeline Low Dose		Week 6	90.0	60.0	30.0
Xanomeline Low Dose		Week 6	80.0	70.0	10.0
Xanomeline Low Dose		Week 8	86.0	80.0	6.0
Xanomeline Low Dose		Week 8	90.0	60.0	30.0
Xanomeline Low Dose		Week 8	78.0	70.0	8.0
Xanomeline Low Dose			76.0	80.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			78.0	70.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			74.0	60.0
Xanomeline Low Dose			80.0	70.0
Xanomeline Low Dose		Week 2	68.0	60.0	8.0
Xanomeline Low Dose		Week 2	78.0	66.0	12.0
Xanomeline Low Dose		Week 2	78.0	68.0	10.0
Xanomeline Low Dose		Week 4	70.0	60.0	10.0
Xanomeline Low Dose		Week 4	80.0	66.0	14.0
Xanomeline Low Dose		Week 4	84.0	68.0	16.0
Xanomeline Low Dose		Week 6	60.0	60.0	0.0
Xanomeline Low Dose		Week 6	62.0	66.0	-4.0
Xanomeline Low Dose		Week 6	60.0	68.0	-8.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			60.0	66.0
Xanomeline Low Dose			64.0	68.0
Placebo		Week 12	68.0	80.0	-12.0
Placebo		Week 12	60.0	76.0	-16.0
Placebo		Week 12	70.0	74.0	-4.0
Placebo		Week 16	62.0	80.0	-18.0
Placebo		Week 16	80.0	76.0	4.0
Placebo		Week 16	80.0	74.0	6.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	70.0	76.0	-6.0
Placebo		Week 2	72.0	74.0	-2.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	64.0	76.0	-12.0
Placebo		Week 20	60.0	74.0	-14.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 4	82.0	74.0	8.0
Placebo		Week 6	82.0	80.0	2.0
Placebo		Week 6	78.0	76.0	2.0
Placebo		Week 6	82.0	74.0	8.0
Placebo		Week 8	64.0	80.0	-16.0
Placebo		Week 8	60.0	76.0	-16.0
Placebo		Week 8	60.0	74.0	-14.0
Placebo			70.0	80.0
Placebo			70.0	76.0
Placebo			70.0	74.0
Xanomeline High Dose		Week 12	88.0	88.0	0.0
Xanomeline High Dose		Week 12	84.0	80.0	4.0
Xanomeline High Dose		Week 12	86.0	80.0	6.0
Xanomeline High Dose		Week 16	78.0	88.0	-10.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 2	80.0	88.0	-8.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 20	64.0	88.0	-24.0
Xanomeline High Dose		Week 20	76.0	80.0	-4.0
Xanomeline High Dose		Week 20	84.0	80.0	4.0
Xanomeline High Dose		Week 24	92.0	88.0	4.0
Xanomeline High Dose		Week 24	94.0	80.0	14.0
Xanomeline High Dose		Week 24	92.0	80.0	12.0
Xanomeline High Dose		Week 26	78.0	88.0	-10.0
Xanomeline High Dose		Week 26	90.0	80.0	10.0
Xanomeline High Dose		Week 26	78.0	80.0	-2.0
Xanomeline High Dose		Week 4	94.0	88.0	6.0
Xanomeline High Dose		Week 4	98.0	80.0	18.0
Xanomeline High Dose		Week 4	100.0	80.0	20.0
Xanomeline High Dose		Week 6	78.0	88.0	-10.0
Xanomeline High Dose		Week 6	64.0	80.0	-16.0
Xanomeline High Dose		Week 6	76.0	80.0	-4.0
Xanomeline High Dose		Week 8	70.0	88.0	-18.0
Xanomeline High Dose		Week 8	70.0	80.0	-10.0
Xanomeline High Dose		Week 8	76.0	80.0	-4.0
Xanomeline High Dose			90.0	88.0
Xanomeline High Dose			100.0	80.0
Xanomeline High Dose			90.0	80.0
Xanomeline High Dose			84.0	88.0
Xanomeline High Dose			92.0	80.0
Xanomeline High Dose			90.0	80.0
Xanomeline Low Dose		Week 2	90.0	88.0	2.0
Xanomeline Low Dose		Week 2	90.0	78.0	12.0
Xanomeline Low Dose		Week 2	90.0	78.0	12.0
Xanomeline Low Dose		Week 4	80.0	88.0	-8.0
Xanomeline Low Dose		Week 4	82.0	78.0	4.0
Xanomeline Low Dose		Week 4	80.0	78.0	2.0
Xanomeline Low Dose			85.0	88.0
Xanomeline Low Dose			82.0	78.0
Xanomeline Low Dose			80.0	78.0
Xanomeline Low Dose			70.0	88.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			76.0	78.0
Placebo		Week 12	60.0	86.0	-26.0
Placebo		Week 12	72.0	94.0	-22.0
Placebo		Week 12	72.0	96.0	-24.0
Placebo		Week 16	82.0	86.0	-4.0
Placebo		Week 16	84.0	94.0	-10.0
Placebo		Week 16	88.0	96.0	-8.0
Placebo		Week 2	78.0	86.0	-8.0
Placebo		Week 2	88.0	94.0	-6.0
Placebo		Week 2	94.0	96.0	-2.0
Placebo		Week 20	82.0	86.0	-4.0
Placebo		Week 20	84.0	94.0	-10.0
Placebo		Week 20	88.0	96.0	-8.0
Placebo		Week 24	82.0	86.0	-4.0
Placebo		Week 24	82.0	94.0	-12.0
Placebo		Week 24	88.0	96.0	-8.0
Placebo		Week 26	78.0	86.0	-8.0
Placebo		Week 26	86.0	94.0	-8.0
Placebo		Week 26	80.0	96.0	-16.0
Placebo		Week 4	80.0	86.0	-6.0
Placebo		Week 4	76.0	94.0	-18.0
Placebo		Week 4	88.0	96.0	-8.0
Placebo		Week 6	70.0	86.0	-16.0
Placebo		Week 6	68.0	94.0	-26.0
Placebo		Week 6	80.0	96.0	-16.0
Placebo		Week 8	80.0	86.0	-6.0
Placebo		Week 8	76.0	94.0	-18.0
Placebo		Week 8	88.0	96.0	-8.0
Placebo			82.0	86.0
Placebo			80.0	94.0
Placebo			80.0	96.0
Placebo			82.0	86.0
Placebo			80.0	94.0
Placebo			88.0	96.0
Xanomeline Low Dose		Week 2	78.0	88.0	-10.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose			80.0	88.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose		Week 12	96.0	88.0	8.0
Xanomeline Low Dose		Week 12	86.0	90.0	-4.0
Xanomeline Low Dose		Week 12	90.0	92.0	-2.0
Xanomeline Low Dose		Week 16	88.0	88.0	0.0
Xanomeline Low Dose		Week 16	76.0	90.0	-14.0
Xanomeline Low Dose		Week 16	76.0	92.0	-16.0
Xanomeline Low Dose		Week 2	90.0	88.0	2.0
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	88.0	92.0	-4.0
Xanomeline Low Dose		Week 20	76.0	88.0	-12.0
Xanomeline Low Dose		Week 20	76.0	90.0	-14.0
Xanomeline Low Dose		Week 20	76.0	92.0	-16.0
Xanomeline Low Dose		Week 24	82.0	88.0	-6.0
Xanomeline Low Dose		Week 24	80.0	90.0	-10.0
Xanomeline Low Dose		Week 24	78.0	92.0	-14.0
Xanomeline Low Dose		Week 26	80.0	88.0	-8.0
Xanomeline Low Dose		Week 26	80.0	90.0	-10.0
Xanomeline Low Dose		Week 26	80.0	92.0	-12.0
Xanomeline Low Dose		Week 4	98.0	88.0	10.0
Xanomeline Low Dose		Week 4	80.0	90.0	-10.0
Xanomeline Low Dose		Week 4	82.0	92.0	-10.0
Xanomeline Low Dose		Week 6	90.0	88.0	2.0
Xanomeline Low Dose		Week 6	80.0	90.0	-10.0
Xanomeline Low Dose		Week 6	80.0	92.0	-12.0
Xanomeline Low Dose		Week 8	80.0	88.0	-8.0
Xanomeline Low Dose		Week 8	80.0	90.0	-10.0
Xanomeline Low Dose		Week 8	82.0	92.0	-10.0
Xanomeline High Dose		Week 12	70.0	72.0	-2.0
Xanomeline High Dose		Week 12	70.0	68.0	2.0
Xanomeline High Dose		Week 12	72.0	70.0	2.0
Xanomeline High Dose		Week 16	74.0	72.0	2.0
Xanomeline High Dose		Week 16	70.0	68.0	2.0
Xanomeline High Dose		Week 16	74.0	70.0	4.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	62.0	68.0	-6.0
Xanomeline High Dose		Week 2	66.0	70.0	-4.0
Xanomeline High Dose		Week 20	72.0	72.0	0.0
Xanomeline High Dose		Week 20	72.0	68.0	4.0
Xanomeline High Dose		Week 20	68.0	70.0	-2.0
Xanomeline High Dose		Week 24	66.0	72.0	-6.0
Xanomeline High Dose		Week 24	60.0	68.0	-8.0
Xanomeline High Dose		Week 24	74.0	70.0	4.0
Xanomeline High Dose		Week 26	62.0	72.0	-10.0
Xanomeline High Dose		Week 26	68.0	68.0	0.0
Xanomeline High Dose		Week 26	58.0	70.0	-12.0
Xanomeline High Dose		Week 4	86.0	72.0	14.0
Xanomeline High Dose		Week 4	90.0	68.0	22.0
Xanomeline High Dose		Week 4	82.0	70.0	12.0
Xanomeline High Dose		Week 6	70.0	72.0	-2.0
Xanomeline High Dose		Week 6	78.0	68.0	10.0
Xanomeline High Dose		Week 6	76.0	70.0	6.0
Xanomeline High Dose		Week 8	72.0	72.0	0.0
Xanomeline High Dose		Week 8	78.0	68.0	10.0
Xanomeline High Dose		Week 8	74.0	70.0	4.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			74.0	68.0
Xanomeline High Dose			72.0	70.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			66.0	68.0
Xanomeline High Dose			70.0	70.0
Xanomeline Low Dose		Week 12	68.0	60.0	8.0
Xanomeline Low Dose		Week 12	50.0	56.0	-6.0
Xanomeline Low Dose		Week 12	50.0	60.0	-10.0
Xanomeline Low Dose		Week 2	66.0	60.0	6.0
Xanomeline Low Dose		Week 2	68.0	56.0	12.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 4	74.0	60.0	14.0
Xanomeline Low Dose		Week 4	78.0	56.0	22.0
Xanomeline Low Dose		Week 4	72.0	60.0	12.0
Xanomeline Low Dose		Week 6	62.0	60.0	2.0
Xanomeline Low Dose		Week 6	60.0	56.0	4.0
Xanomeline Low Dose		Week 6	64.0	60.0	4.0
Xanomeline Low Dose		Week 8	74.0	60.0	14.0
Xanomeline Low Dose		Week 8	66.0	56.0	10.0
Xanomeline Low Dose		Week 8	80.0	60.0	20.0
Xanomeline Low Dose			66.0	60.0
Xanomeline Low Dose			68.0	56.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			58.0	60.0
Xanomeline Low Dose			62.0	56.0
Xanomeline Low Dose			60.0	60.0
Placebo		Week 12	74.0	72.0	2.0
Placebo		Week 12	80.0	76.0	4.0
Placebo		Week 12	82.0	80.0	2.0
Placebo		Week 16	70.0	72.0	-2.0
Placebo		Week 16	80.0	76.0	4.0
Placebo		Week 16	84.0	80.0	4.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	70.0	76.0	-6.0
Placebo		Week 2	76.0	80.0	-4.0
Placebo		Week 20	78.0	72.0	6.0
Placebo		Week 20	84.0	76.0	8.0
Placebo		Week 20	86.0	80.0	6.0
Placebo		Week 24	80.0	72.0	8.0
Placebo		Week 24	78.0	76.0	2.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 26	78.0	72.0	6.0
Placebo		Week 26	80.0	76.0	4.0
Placebo		Week 26	72.0	80.0	-8.0
Placebo		Week 4	78.0	72.0	6.0
Placebo		Week 4	78.0	76.0	2.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 6	80.0	72.0	8.0
Placebo		Week 6	78.0	76.0	2.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 8	84.0	72.0	12.0
Placebo		Week 8	80.0	76.0	4.0
Placebo		Week 8	84.0	80.0	4.0
Placebo			82.0	72.0
Placebo			80.0	76.0
Placebo			72.0	80.0
Placebo			78.0	72.0
Placebo			80.0	76.0
Placebo			78.0	80.0
Xanomeline High Dose		Week 12	82.0	80.0	2.0
Xanomeline High Dose		Week 12	80.0	90.0	-10.0
Xanomeline High Dose		Week 12	74.0	88.0	-14.0
Xanomeline High Dose		Week 16	78.0	80.0	-2.0
Xanomeline High Dose		Week 16	76.0	90.0	-14.0
Xanomeline High Dose		Week 16	74.0	88.0	-14.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	90.0	90.0	0.0
Xanomeline High Dose		Week 2	84.0	88.0	-4.0
Xanomeline High Dose		Week 20	70.0	80.0	-10.0
Xanomeline High Dose		Week 20	70.0	90.0	-20.0
Xanomeline High Dose		Week 20	72.0	88.0	-16.0
Xanomeline High Dose		Week 24	80.0	80.0	0.0
Xanomeline High Dose		Week 24	80.0	90.0	-10.0
Xanomeline High Dose		Week 24	90.0	88.0	2.0
Xanomeline High Dose		Week 26	70.0	80.0	-10.0
Xanomeline High Dose		Week 26	72.0	90.0	-18.0
Xanomeline High Dose		Week 26	80.0	88.0	-8.0
Xanomeline High Dose		Week 4	82.0	80.0	2.0
Xanomeline High Dose		Week 4	80.0	90.0	-10.0
Xanomeline High Dose		Week 4	80.0	88.0	-8.0
Xanomeline High Dose		Week 6	70.0	80.0	-10.0
Xanomeline High Dose		Week 6	70.0	90.0	-20.0
Xanomeline High Dose		Week 6	68.0	88.0	-20.0
Xanomeline High Dose		Week 8	82.0	80.0	2.0
Xanomeline High Dose		Week 8	90.0	90.0	0.0
Xanomeline High Dose		Week 8	88.0	88.0	0.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			74.0	90.0
Xanomeline High Dose			74.0	88.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	90.0
Xanomeline High Dose			80.0	88.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 2	78.0	54.0	24.0
Xanomeline Low Dose		Week 2	74.0	74.0	0.0
Xanomeline Low Dose		Week 4	80.0	72.0	8.0
Xanomeline Low Dose		Week 4	82.0	54.0	28.0
Xanomeline Low Dose		Week 4	88.0	74.0	14.0
Xanomeline Low Dose		Week 6	80.0	72.0	8.0
Xanomeline Low Dose		Week 6	80.0	54.0	26.0
Xanomeline Low Dose		Week 6	80.0	74.0	6.0
Xanomeline Low Dose		Week 8	84.0	72.0	12.0
Xanomeline Low Dose		Week 8	80.0	54.0	26.0
Xanomeline Low Dose		Week 8	78.0	74.0	4.0
Xanomeline Low Dose			86.0	72.0
Xanomeline Low Dose			80.0	54.0
Xanomeline Low Dose			78.0	74.0
Xanomeline Low Dose			82.0	72.0
Xanomeline Low Dose			68.0	54.0
Xanomeline Low Dose			68.0	74.0
Xanomeline High Dose		Week 2	74.0	84.0	-10.0
Xanomeline High Dose		Week 2	68.0	82.0	-14.0
Xanomeline High Dose		Week 2	68.0	80.0	-12.0
Xanomeline High Dose		Week 4	76.0	84.0	-8.0
Xanomeline High Dose		Week 4	82.0	82.0	0.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 6	84.0	84.0	0.0
Xanomeline High Dose		Week 6	84.0	82.0	2.0
Xanomeline High Dose		Week 6	78.0	80.0	-2.0
Xanomeline High Dose			82.0	84.0
Xanomeline High Dose			74.0	82.0
Xanomeline High Dose			70.0	80.0
Xanomeline Low Dose		Week 12	62.0	68.0	-6.0
Xanomeline Low Dose		Week 12	64.0	72.0	-8.0
Xanomeline Low Dose		Week 12	64.0	70.0	-6.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	70.0	68.0	2.0
Xanomeline Low Dose		Week 4	70.0	72.0	-2.0
Xanomeline Low Dose		Week 4	70.0	70.0	0.0
Xanomeline Low Dose		Week 6	74.0	68.0	6.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 6	70.0	70.0	0.0
Xanomeline Low Dose		Week 8	60.0	68.0	-8.0
Xanomeline Low Dose		Week 8	60.0	72.0	-12.0
Xanomeline Low Dose		Week 8	64.0	70.0	-6.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose			80.0	70.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			80.0	72.0
Xanomeline Low Dose			70.0	70.0
Xanomeline High Dose		Week 2	90.0	78.0	12.0
Xanomeline High Dose		Week 2	72.0	90.0	-18.0
Xanomeline High Dose		Week 2	86.0	90.0	-4.0
Xanomeline High Dose		Week 4	80.0	78.0	2.0
Xanomeline High Dose		Week 4	84.0	90.0	-6.0
Xanomeline High Dose		Week 4	82.0	90.0	-8.0
Xanomeline High Dose		Week 6	76.0	78.0	-2.0
Xanomeline High Dose		Week 6	70.0	90.0	-20.0
Xanomeline High Dose		Week 6	70.0	90.0	-20.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose		Week 8	72.0	90.0	-18.0
Xanomeline High Dose		Week 8	72.0	90.0	-18.0
Xanomeline High Dose			78.0	78.0
Xanomeline High Dose			82.0	90.0
Xanomeline High Dose			82.0	90.0
Placebo		Week 12	60.0	68.0	-8.0
Placebo		Week 12	60.0	62.0	-2.0
Placebo		Week 12	60.0	64.0	-4.0
Placebo		Week 16	68.0	68.0	0.0
Placebo		Week 16	54.0	62.0	-8.0
Placebo		Week 16	64.0	64.0	0.0
Placebo		Week 2	64.0	68.0	-4.0
Placebo		Week 2	64.0	62.0	2.0
Placebo		Week 2	60.0	64.0	-4.0
Placebo		Week 20	68.0	68.0	0.0
Placebo		Week 20	60.0	62.0	-2.0
Placebo		Week 20	62.0	64.0	-2.0
Placebo		Week 4	60.0	68.0	-8.0
Placebo		Week 4	56.0	62.0	-6.0
Placebo		Week 4	60.0	64.0	-4.0
Placebo		Week 6	68.0	68.0	0.0
Placebo		Week 6	62.0	62.0	0.0
Placebo		Week 6	70.0	64.0	6.0
Placebo		Week 8	70.0	68.0	2.0
Placebo		Week 8	68.0	62.0	6.0
Placebo		Week 8	64.0	64.0	0.0
Placebo			58.0	68.0
Placebo			60.0	62.0
Placebo			60.0	64.0
Placebo			68.0	68.0
Placebo			64.0	62.0
Placebo			62.0	64.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	80.0	88.0	-8.0
Xanomeline Low Dose		Week 2	78.0	82.0	-4.0
Xanomeline Low Dose		Week 4	70.0	72.0	-2.0
Xanomeline Low Dose		Week 4	80.0	88.0	-8.0
Xanomeline Low Dose		Week 4	82.0	82.0	0.0
Xanomeline Low Dose		Week 6	70.0	72.0	-2.0
Xanomeline Low Dose		Week 6	80.0	88.0	-8.0
Xanomeline Low Dose		Week 6	80.0	82.0	-2.0
Xanomeline Low Dose		Week 8	68.0	72.0	-4.0
Xanomeline Low Dose		Week 8	70.0	88.0	-18.0
Xanomeline Low Dose		Week 8	80.0	82.0	-2.0
Xanomeline Low Dose			74.0	72.0
Xanomeline Low Dose			80.0	88.0
Xanomeline Low Dose			82.0	82.0
Xanomeline Low Dose			78.0	72.0
Xanomeline Low Dose			84.0	88.0
Xanomeline Low Dose			88.0	82.0
Placebo		Week 12	78.0	88.0	-10.0
Placebo		Week 12	78.0	88.0	-10.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 16	82.0	88.0	-6.0
Placebo		Week 16	80.0	88.0	-8.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 2	88.0	88.0	0.0
Placebo		Week 2	86.0	88.0	-2.0
Placebo		Week 2	82.0	80.0	2.0
Placebo		Week 20	70.0	88.0	-18.0
Placebo		Week 20	72.0	88.0	-16.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 24	78.0	88.0	-10.0
Placebo		Week 24	80.0	88.0	-8.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 26	88.0	88.0	0.0
Placebo		Week 26	82.0	88.0	-6.0
Placebo		Week 26	84.0	80.0	4.0
Placebo		Week 4	78.0	88.0	-10.0
Placebo		Week 4	76.0	88.0	-12.0
Placebo		Week 4	76.0	80.0	-4.0
Placebo		Week 6	94.0	88.0	6.0
Placebo		Week 6	80.0	88.0	-8.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 8	92.0	88.0	4.0
Placebo		Week 8	88.0	88.0	0.0
Placebo		Week 8	84.0	80.0	4.0
Placebo			80.0	88.0
Placebo			80.0	88.0
Placebo			78.0	80.0
Placebo			80.0	88.0
Placebo			90.0	88.0
Placebo			88.0	80.0
Placebo		Week 12	80.0	86.0	-6.0
Placebo		Week 12	80.0	94.0	-14.0
Placebo		Week 12	82.0	84.0	-2.0
Placebo		Week 16	82.0	86.0	-4.0
Placebo		Week 16	80.0	94.0	-14.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 2	74.0	86.0	-12.0
Placebo		Week 2	70.0	94.0	-24.0
Placebo		Week 2	80.0	84.0	-4.0
Placebo		Week 4	82.0	86.0	-4.0
Placebo		Week 4	90.0	94.0	-4.0
Placebo		Week 4	90.0	84.0	6.0
Placebo		Week 6	80.0	86.0	-6.0
Placebo		Week 6	80.0	94.0	-14.0
Placebo		Week 6	78.0	84.0	-6.0
Placebo		Week 8	84.0	86.0	-2.0
Placebo		Week 8	80.0	94.0	-14.0
Placebo		Week 8	82.0	84.0	-2.0
Placebo			80.0	86.0
Placebo			82.0	94.0
Placebo			76.0	84.0
Placebo			90.0	86.0
Placebo			92.0	94.0
Placebo			90.0	84.0
Xanomeline High Dose		Week 12	78.0	80.0	-2.0
Xanomeline High Dose		Week 12	82.0	80.0	2.0
Xanomeline High Dose		Week 12	80.0	84.0	-4.0
Xanomeline High Dose		Week 16	76.0	80.0	-4.0
Xanomeline High Dose		Week 16	82.0	80.0	2.0
Xanomeline High Dose		Week 16	80.0	84.0	-4.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	90.0	84.0	6.0
Xanomeline High Dose		Week 20	78.0	80.0	-2.0
Xanomeline High Dose		Week 20	82.0	80.0	2.0
Xanomeline High Dose		Week 20	80.0	84.0	-4.0
Xanomeline High Dose		Week 24	60.0	80.0	-20.0
Xanomeline High Dose		Week 24	68.0	80.0	-12.0
Xanomeline High Dose		Week 24	70.0	84.0	-14.0
Xanomeline High Dose		Week 26	74.0	80.0	-6.0
Xanomeline High Dose		Week 26	84.0	80.0	4.0
Xanomeline High Dose		Week 26	80.0	84.0	-4.0
Xanomeline High Dose		Week 4	82.0	80.0	2.0
Xanomeline High Dose		Week 4	80.0	80.0	0.0
Xanomeline High Dose		Week 4	82.0	84.0	-2.0
Xanomeline High Dose		Week 6	90.0	80.0	10.0
Xanomeline High Dose		Week 6	90.0	80.0	10.0
Xanomeline High Dose		Week 6	90.0	84.0	6.0
Xanomeline High Dose		Week 8	84.0	80.0	4.0
Xanomeline High Dose		Week 8	90.0	80.0	10.0
Xanomeline High Dose		Week 8	90.0	84.0	6.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			90.0	80.0
Xanomeline High Dose			90.0	84.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			94.0	84.0
Placebo		Week 12	72.0	90.0	-18.0
Placebo		Week 12	68.0	82.0	-14.0
Placebo		Week 12	72.0	84.0	-12.0
Placebo		Week 16	78.0	90.0	-12.0
Placebo		Week 16	74.0	82.0	-8.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 2	74.0	90.0	-16.0
Placebo		Week 2	60.0	82.0	-22.0
Placebo		Week 2	70.0	84.0	-14.0
Placebo		Week 20	80.0	90.0	-10.0
Placebo		Week 20	72.0	82.0	-10.0
Placebo		Week 20	78.0	84.0	-6.0
Placebo		Week 24	78.0	90.0	-12.0
Placebo		Week 24	76.0	82.0	-6.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 26	72.0	90.0	-18.0
Placebo		Week 26	70.0	82.0	-12.0
Placebo		Week 26	80.0	84.0	-4.0
Placebo		Week 4	78.0	90.0	-12.0
Placebo		Week 4	64.0	82.0	-18.0
Placebo		Week 4	70.0	84.0	-14.0
Placebo		Week 6	72.0	90.0	-18.0
Placebo		Week 6	84.0	82.0	2.0
Placebo		Week 6	82.0	84.0	-2.0
Placebo		Week 8	74.0	90.0	-16.0
Placebo		Week 8	70.0	82.0	-12.0
Placebo		Week 8	80.0	84.0	-4.0
Placebo			80.0	90.0
Placebo			80.0	82.0
Placebo			78.0	84.0
Xanomeline Low Dose		Week 12	92.0	90.0	2.0
Xanomeline Low Dose		Week 12	98.0	90.0	8.0
Xanomeline Low Dose		Week 12	90.0	100.0	-10.0
Xanomeline Low Dose		Week 16	92.0	90.0	2.0
Xanomeline Low Dose		Week 16	98.0	90.0	8.0
Xanomeline Low Dose		Week 16	90.0	100.0	-10.0
Xanomeline Low Dose		Week 2	92.0	90.0	2.0
Xanomeline Low Dose		Week 2	100.0	90.0	10.0
Xanomeline Low Dose		Week 2	100.0	100.0	0.0
Xanomeline Low Dose		Week 20	90.0	90.0	0.0
Xanomeline Low Dose		Week 20	98.0	90.0	8.0
Xanomeline Low Dose		Week 20	90.0	100.0	-10.0
Xanomeline Low Dose		Week 24	90.0	90.0	0.0
Xanomeline Low Dose		Week 24	98.0	90.0	8.0
Xanomeline Low Dose		Week 24	98.0	100.0	-2.0
Xanomeline Low Dose		Week 26	80.0	90.0	-10.0
Xanomeline Low Dose		Week 26	92.0	90.0	2.0
Xanomeline Low Dose		Week 26	90.0	100.0	-10.0
Xanomeline Low Dose		Week 4	96.0	90.0	6.0
Xanomeline Low Dose		Week 4	98.0	90.0	8.0
Xanomeline Low Dose		Week 4	98.0	100.0	-2.0
Xanomeline Low Dose		Week 6	92.0	90.0	2.0
Xanomeline Low Dose		Week 6	96.0	90.0	6.0
Xanomeline Low Dose		Week 6	98.0	100.0	-2.0
Xanomeline Low Dose		Week 8	84.0	90.0	-6.0
Xanomeline Low Dose		Week 8	90.0	90.0	0.0
Xanomeline Low Dose		Week 8	90.0	100.0	-10.0
Xanomeline Low Dose			86.0	90.0
Xanomeline Low Dose			90.0	90.0
Xanomeline Low Dose			94.0	100.0
Xanomeline Low Dose			90.0	90.0
Xanomeline Low Dose			90.0	90.0
Xanomeline Low Dose			92.0	100.0
Placebo		Week 12	72.0	72.0	0.0
Placebo		Week 12	68.0	74.0	-6.0
Placebo		Week 12	78.0	78.0	0.0
Placebo		Week 16	76.0	72.0	4.0
Placebo		Week 16	72.0	74.0	-2.0
Placebo		Week 16	82.0	78.0	4.0
Placebo		Week 2	68.0	72.0	-4.0
Placebo		Week 2	64.0	74.0	-10.0
Placebo		Week 2	68.0	78.0	-10.0
Placebo		Week 20	80.0	72.0	8.0
Placebo		Week 20	84.0	74.0	10.0
Placebo		Week 20	78.0	78.0	0.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 24	88.0	74.0	14.0
Placebo		Week 24	78.0	78.0	0.0
Placebo		Week 26	76.0	72.0	4.0
Placebo		Week 26	80.0	74.0	6.0
Placebo		Week 26	80.0	78.0	2.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	76.0	74.0	2.0
Placebo		Week 4	76.0	78.0	-2.0
Placebo		Week 6	76.0	72.0	4.0
Placebo		Week 6	78.0	74.0	4.0
Placebo		Week 6	78.0	78.0	0.0
Placebo		Week 8	62.0	72.0	-10.0
Placebo		Week 8	76.0	74.0	2.0
Placebo		Week 8	72.0	78.0	-6.0
Placebo			78.0	72.0
Placebo			78.0	74.0
Placebo			78.0	78.0
Placebo			74.0	72.0
Placebo			68.0	74.0
Placebo			70.0	78.0
Xanomeline Low Dose		Week 2	80.0	70.0	10.0
Xanomeline Low Dose		Week 2	80.0	78.0	2.0
Xanomeline Low Dose		Week 2	82.0	80.0	2.0
Xanomeline High Dose		Week 12	76.0	80.0	-4.0
Xanomeline High Dose		Week 12	70.0	96.0	-26.0
Xanomeline High Dose		Week 12	72.0	90.0	-18.0
Xanomeline High Dose		Week 16	90.0	80.0	10.0
Xanomeline High Dose		Week 16	86.0	96.0	-10.0
Xanomeline High Dose		Week 16	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	84.0	96.0	-12.0
Xanomeline High Dose		Week 2	82.0	90.0	-8.0
Xanomeline High Dose		Week 20	70.0	80.0	-10.0
Xanomeline High Dose		Week 20	80.0	96.0	-16.0
Xanomeline High Dose		Week 20	78.0	90.0	-12.0
Xanomeline High Dose		Week 24	80.0	80.0	0.0
Xanomeline High Dose		Week 24	86.0	96.0	-10.0
Xanomeline High Dose		Week 24	84.0	90.0	-6.0
Xanomeline High Dose		Week 4	90.0	80.0	10.0
Xanomeline High Dose		Week 4	90.0	96.0	-6.0
Xanomeline High Dose		Week 4	86.0	90.0	-4.0
Xanomeline High Dose		Week 6	84.0	80.0	4.0
Xanomeline High Dose		Week 6	86.0	96.0	-10.0
Xanomeline High Dose		Week 6	84.0	90.0	-6.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose		Week 8	84.0	96.0	-12.0
Xanomeline High Dose		Week 8	82.0	90.0	-8.0
Xanomeline High Dose			90.0	80.0
Xanomeline High Dose			90.0	96.0
Xanomeline High Dose			88.0	90.0
Xanomeline High Dose			90.0	80.0
Xanomeline High Dose			88.0	96.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose		Week 2	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	84.0	82.0	2.0
Xanomeline High Dose		Week 2	84.0	80.0	4.0
Xanomeline High Dose		Week 4	90.0	90.0	0.0
Xanomeline High Dose		Week 4	84.0	82.0	2.0
Xanomeline High Dose		Week 4	86.0	80.0	6.0
Xanomeline High Dose			80.0	90.0
Xanomeline High Dose			80.0	82.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			78.0	90.0
Xanomeline High Dose			80.0	82.0
Xanomeline High Dose			76.0	80.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	70.0	82.0	-12.0
Placebo		Week 12	75.0	84.0	-9.0
Placebo		Week 16	66.0	80.0	-14.0
Placebo		Week 16	64.0	82.0	-18.0
Placebo		Week 16	62.0	84.0	-22.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	70.0	82.0	-12.0
Placebo		Week 2	74.0	84.0	-10.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	70.0	82.0	-12.0
Placebo		Week 20	72.0	84.0	-12.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 24	84.0	82.0	2.0
Placebo		Week 24	82.0	84.0	-2.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 26	74.0	82.0	-8.0
Placebo		Week 26	72.0	84.0	-12.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 4	74.0	82.0	-8.0
Placebo		Week 4	72.0	84.0	-12.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	74.0	82.0	-8.0
Placebo		Week 6	76.0	84.0	-8.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	70.0	82.0	-12.0
Placebo		Week 8	72.0	84.0	-12.0
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	88.0	92.0	-4.0
Xanomeline Low Dose		Week 4	80.0	90.0	-10.0
Xanomeline Low Dose		Week 4	82.0	90.0	-8.0
Xanomeline Low Dose		Week 4	80.0	92.0	-12.0
Xanomeline Low Dose		Week 6	78.0	90.0	-12.0
Xanomeline Low Dose		Week 6	84.0	90.0	-6.0
Xanomeline Low Dose		Week 6	80.0	92.0	-12.0
Xanomeline Low Dose		Week 8	90.0	90.0	0.0
Xanomeline Low Dose		Week 8	92.0	90.0	2.0
Xanomeline Low Dose		Week 8	90.0	92.0	-2.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			90.0	90.0
Xanomeline Low Dose			88.0	92.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			88.0	90.0
Xanomeline Low Dose			84.0	92.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	72.0	74.0	-2.0
Xanomeline Low Dose		Week 2	76.0	72.0	4.0
Xanomeline Low Dose		Week 4	84.0	80.0	4.0
Xanomeline Low Dose		Week 4	88.0	74.0	14.0
Xanomeline Low Dose		Week 4	86.0	72.0	14.0
Xanomeline Low Dose		Week 6	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	80.0	74.0	6.0
Xanomeline Low Dose		Week 6	76.0	72.0	4.0
Xanomeline Low Dose			68.0	80.0
Xanomeline Low Dose			78.0	74.0
Xanomeline Low Dose			74.0	72.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			75.0	74.0
Xanomeline Low Dose			72.0	72.0
Placebo		Week 12	80.0	70.0	10.0
Placebo		Week 12	90.0	80.0	10.0
Placebo		Week 12	88.0	76.0	12.0
Placebo		Week 16	90.0	70.0	20.0
Placebo		Week 16	96.0	80.0	16.0
Placebo		Week 16	98.0	76.0	22.0
Placebo		Week 2	90.0	70.0	20.0
Placebo		Week 2	94.0	80.0	14.0
Placebo		Week 2	92.0	76.0	16.0
Placebo		Week 20	80.0	70.0	10.0
Placebo		Week 20	90.0	80.0	10.0
Placebo		Week 20	88.0	76.0	12.0
Placebo		Week 24	96.0	70.0	26.0
Placebo		Week 24	98.0	80.0	18.0
Placebo		Week 24	96.0	76.0	20.0
Placebo		Week 26	90.0	70.0	20.0
Placebo		Week 26	92.0	80.0	12.0
Placebo		Week 26	90.0	76.0	14.0
Placebo		Week 4	90.0	70.0	20.0
Placebo		Week 4	90.0	80.0	10.0
Placebo		Week 4	90.0	76.0	14.0
Placebo		Week 6	80.0	70.0	10.0
Placebo		Week 6	85.0	80.0	5.0
Placebo		Week 6	82.0	76.0	6.0
Placebo		Week 8	90.0	70.0	20.0
Placebo		Week 8	84.0	80.0	4.0
Placebo		Week 8	82.0	76.0	6.0
Placebo			80.0	70.0
Placebo			74.0	80.0
Placebo			78.0	76.0
Placebo			80.0	70.0
Placebo			86.0	80.0
Placebo			84.0	76.0
Xanomeline High Dose		Week 12	90.0	70.0	20.0
Xanomeline High Dose		Week 12	92.0	80.0	12.0
Xanomeline High Dose		Week 12	90.0	82.0	8.0
Xanomeline High Dose		Week 16	74.0	70.0	4.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 16	82.0	82.0	0.0
Xanomeline High Dose		Week 2	68.0	70.0	-2.0
Xanomeline High Dose		Week 2	72.0	80.0	-8.0
Xanomeline High Dose		Week 2	70.0	82.0	-12.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 4	90.0	80.0	10.0
Xanomeline High Dose		Week 4	92.0	82.0	10.0
Xanomeline High Dose		Week 6	86.0	70.0	16.0
Xanomeline High Dose		Week 6	84.0	80.0	4.0
Xanomeline High Dose		Week 6	84.0	82.0	2.0
Xanomeline High Dose		Week 8	80.0	70.0	10.0
Xanomeline High Dose		Week 8	82.0	80.0	2.0
Xanomeline High Dose		Week 8	82.0	82.0	0.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			76.0	82.0
Placebo		Week 12	84.0	90.0	-6.0
Placebo		Week 12	86.0	80.0	6.0
Placebo		Week 12	88.0	82.0	6.0
Placebo		Week 16	78.0	90.0	-12.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	82.0	82.0	0.0
Placebo		Week 2	70.0	90.0	-20.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	68.0	82.0	-14.0
Placebo		Week 20	80.0	90.0	-10.0
Placebo		Week 20	80.0	80.0	0.0
Placebo		Week 20	84.0	82.0	2.0
Placebo		Week 24	78.0	90.0	-12.0
Placebo		Week 24	70.0	80.0	-10.0
Placebo		Week 24	74.0	82.0	-8.0
Placebo		Week 26	70.0	90.0	-20.0
Placebo		Week 26	68.0	80.0	-12.0
Placebo		Week 26	64.0	82.0	-18.0
Placebo		Week 4	80.0	90.0	-10.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	78.0	82.0	-4.0
Placebo		Week 6	80.0	90.0	-10.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 6	78.0	82.0	-4.0
Placebo		Week 8	80.0	90.0	-10.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	78.0	82.0	-4.0
Placebo			72.0	90.0
Placebo			70.0	80.0
Placebo			72.0	82.0
Placebo		Week 12	84.0	84.0	0.0
Placebo		Week 12	82.0	92.0	-10.0
Placebo		Week 12	84.0	94.0	-10.0
Placebo		Week 16	90.0	84.0	6.0
Placebo		Week 16	96.0	92.0	4.0
Placebo		Week 16	92.0	94.0	-2.0
Placebo		Week 2	76.0	84.0	-8.0
Placebo		Week 2	72.0	92.0	-20.0
Placebo		Week 2	70.0	94.0	-24.0
Placebo		Week 20	84.0	84.0	0.0
Placebo		Week 20	88.0	92.0	-4.0
Placebo		Week 20	90.0	94.0	-4.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 24	80.0	92.0	-12.0
Placebo		Week 24	84.0	94.0	-10.0
Placebo		Week 26	70.0	84.0	-14.0
Placebo		Week 26	80.0	92.0	-12.0
Placebo		Week 26	76.0	94.0	-18.0
Placebo		Week 4	82.0	84.0	-2.0
Placebo		Week 4	86.0	92.0	-6.0
Placebo		Week 4	88.0	94.0	-6.0
Placebo		Week 6	80.0	84.0	-4.0
Placebo		Week 6	80.0	92.0	-12.0
Placebo		Week 6	78.0	94.0	-16.0
Placebo		Week 8	80.0	84.0	-4.0
Placebo		Week 8	86.0	92.0	-6.0
Placebo		Week 8	82.0	94.0	-12.0
Placebo			74.0	84.0
Placebo			76.0	92.0
Placebo			70.0	94.0
Placebo			74.0	84.0
Placebo			78.0	92.0
Placebo			74.0	94.0
Xanomeline High Dose		Week 2	90.0	96.0	-6.0
Xanomeline High Dose		Week 2	92.0	100.0	-8.0
Xanomeline High Dose		Week 2	94.0	98.0	-4.0
Xanomeline High Dose		Week 4	82.0	96.0	-14.0
Xanomeline High Dose		Week 4	84.0	100.0	-16.0
Xanomeline High Dose		Week 4	84.0	98.0	-14.0
Xanomeline High Dose		Week 6	94.0	96.0	-2.0
Xanomeline High Dose		Week 6	98.0	100.0	-2.0
Xanomeline High Dose		Week 6	96.0	98.0	-2.0
Xanomeline High Dose			98.0	96.0
Xanomeline High Dose			98.0	100.0
Xanomeline High Dose			98.0	98.0
Xanomeline High Dose			94.0	96.0
Xanomeline High Dose			98.0	100.0
Xanomeline High Dose			98.0	98.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	72.0	76.0	-4.0
Xanomeline High Dose		Week 2	70.0	74.0	-4.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			76.0	76.0
Xanomeline High Dose			74.0	74.0
Xanomeline Low Dose		Week 2	80.0	74.0	6.0
Xanomeline Low Dose		Week 2	78.0	82.0	-4.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	82.0	74.0	8.0
Xanomeline Low Dose		Week 4	84.0	82.0	2.0
Xanomeline Low Dose		Week 4	82.0	80.0	2.0
Xanomeline Low Dose		Week 12	90.0	98.0	-8.0
Xanomeline Low Dose		Week 12	80.0	98.0	-18.0
Xanomeline Low Dose		Week 12	88.0	96.0	-8.0
Xanomeline Low Dose		Week 2	70.0	98.0	-28.0
Xanomeline Low Dose		Week 2	80.0	98.0	-18.0
Xanomeline Low Dose		Week 2	76.0	96.0	-20.0
Xanomeline Low Dose		Week 4	80.0	98.0	-18.0
Xanomeline Low Dose		Week 4	80.0	98.0	-18.0
Xanomeline Low Dose		Week 4	82.0	96.0	-14.0
Xanomeline Low Dose		Week 6	78.0	98.0	-20.0
Xanomeline Low Dose		Week 6	80.0	98.0	-18.0
Xanomeline Low Dose		Week 6	78.0	96.0	-18.0
Xanomeline Low Dose		Week 8	98.0	98.0	0.0
Xanomeline Low Dose		Week 8	98.0	98.0	0.0
Xanomeline Low Dose		Week 8	96.0	96.0	0.0
Xanomeline Low Dose			80.0	98.0
Xanomeline Low Dose			80.0	98.0
Xanomeline Low Dose			76.0	96.0
Xanomeline Low Dose			70.0	98.0
Xanomeline Low Dose			78.0	98.0
Xanomeline Low Dose			74.0	96.0
Placebo		Week 12	86.0	98.0	-12.0
Placebo		Week 12	90.0	92.0	-2.0
Placebo		Week 12	88.0	94.0	-6.0
Placebo		Week 16	90.0	98.0	-8.0
Placebo		Week 16	86.0	92.0	-6.0
Placebo		Week 16	88.0	94.0	-6.0
Placebo		Week 2	90.0	98.0	-8.0
Placebo		Week 2	90.0	92.0	-2.0
Placebo		Week 2	92.0	94.0	-2.0
Placebo		Week 20	80.0	98.0	-18.0
Placebo		Week 20	80.0	92.0	-12.0
Placebo		Week 20	82.0	94.0	-12.0
Placebo		Week 24	80.0	98.0	-18.0
Placebo		Week 24	86.0	92.0	-6.0
Placebo		Week 24	84.0	94.0	-10.0
Placebo		Week 26	90.0	98.0	-8.0
Placebo		Week 26	94.0	92.0	2.0
Placebo		Week 26	92.0	94.0	-2.0
Placebo		Week 4	90.0	98.0	-8.0
Placebo		Week 4	98.0	92.0	6.0
Placebo		Week 4	96.0	94.0	2.0
Placebo		Week 6	90.0	98.0	-8.0
Placebo		Week 6	90.0	92.0	-2.0
Placebo		Week 6	90.0	94.0	-4.0
Placebo		Week 8	84.0	98.0	-14.0
Placebo		Week 8	80.0	92.0	-12.0
Placebo		Week 8	82.0	94.0	-12.0
Placebo			90.0	98.0
Placebo			90.0	92.0
Placebo			92.0	94.0
Placebo			80.0	98.0
Placebo			88.0	92.0
Placebo			84.0	94.0
Xanomeline High Dose		Week 12	80.0	68.0	12.0
Xanomeline High Dose		Week 12	70.0	78.0	-8.0
Xanomeline High Dose		Week 12	72.0	74.0	-2.0
Xanomeline High Dose		Week 16	70.0	68.0	2.0
Xanomeline High Dose		Week 16	80.0	78.0	2.0
Xanomeline High Dose		Week 16	78.0	74.0	4.0
Xanomeline High Dose		Week 2	70.0	68.0	2.0
Xanomeline High Dose		Week 2	78.0	78.0	0.0
Xanomeline High Dose		Week 2	74.0	74.0	0.0
Xanomeline High Dose		Week 20	60.0	68.0	-8.0
Xanomeline High Dose		Week 20	70.0	78.0	-8.0
Xanomeline High Dose		Week 20	68.0	74.0	-6.0
Xanomeline High Dose		Week 24	70.0	68.0	2.0
Xanomeline High Dose		Week 24	68.0	78.0	-10.0
Xanomeline High Dose		Week 24	68.0	74.0	-6.0
Xanomeline High Dose		Week 26	60.0	68.0	-8.0
Xanomeline High Dose		Week 26	70.0	78.0	-8.0
Xanomeline High Dose		Week 26	68.0	74.0	-6.0
Xanomeline High Dose		Week 4	60.0	68.0	-8.0
Xanomeline High Dose		Week 4	70.0	78.0	-8.0
Xanomeline High Dose		Week 4	74.0	74.0	0.0
Xanomeline High Dose		Week 6	64.0	68.0	-4.0
Xanomeline High Dose		Week 6	70.0	78.0	-8.0
Xanomeline High Dose		Week 6	72.0	74.0	-2.0
Xanomeline High Dose		Week 8	62.0	68.0	-6.0
Xanomeline High Dose		Week 8	70.0	78.0	-8.0
Xanomeline High Dose		Week 8	68.0	74.0	-6.0
Xanomeline High Dose			64.0	68.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose			74.0	74.0
Xanomeline Low Dose		Week 12	78.0	90.0	-12.0
Xanomeline Low Dose		Week 12	80.0	92.0	-12.0
Xanomeline Low Dose		Week 12	84.0	90.0	-6.0
Xanomeline Low Dose		Week 16	80.0	90.0	-10.0
Xanomeline Low Dose		Week 16	90.0	92.0	-2.0
Xanomeline Low Dose		Week 16	86.0	90.0	-4.0
Xanomeline Low Dose		Week 2	88.0	90.0	-2.0
Xanomeline Low Dose		Week 2	88.0	92.0	-4.0
Xanomeline Low Dose		Week 2	88.0	90.0	-2.0
Xanomeline Low Dose		Week 20	70.0	90.0	-20.0
Xanomeline Low Dose		Week 20	84.0	92.0	-8.0
Xanomeline Low Dose		Week 20	80.0	90.0	-10.0
Xanomeline Low Dose		Week 24	86.0	90.0	-4.0
Xanomeline Low Dose		Week 24	90.0	92.0	-2.0
Xanomeline Low Dose		Week 24	88.0	90.0	-2.0
Xanomeline Low Dose		Week 26	84.0	90.0	-6.0
Xanomeline Low Dose		Week 26	90.0	92.0	-2.0
Xanomeline Low Dose		Week 26	88.0	90.0	-2.0
Xanomeline Low Dose		Week 4	72.0	90.0	-18.0
Xanomeline Low Dose		Week 4	80.0	92.0	-12.0
Xanomeline Low Dose		Week 4	76.0	90.0	-14.0
Xanomeline Low Dose		Week 6	80.0	90.0	-10.0
Xanomeline Low Dose		Week 6	90.0	92.0	-2.0
Xanomeline Low Dose		Week 6	88.0	90.0	-2.0
Xanomeline Low Dose		Week 8	80.0	90.0	-10.0
Xanomeline Low Dose		Week 8	90.0	92.0	-2.0
Xanomeline Low Dose		Week 8	86.0	90.0	-4.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			84.0	92.0
Xanomeline Low Dose			82.0	90.0
Xanomeline Low Dose			86.0	90.0
Xanomeline Low Dose			90.0	92.0
Xanomeline Low Dose			88.0	90.0
Xanomeline High Dose		Week 12	60.0	60.0	0.0
Xanomeline High Dose		Week 12	66.0	70.0	-4.0
Xanomeline High Dose		Week 12	62.0	72.0	-10.0
Xanomeline High Dose		Week 16	60.0	60.0	0.0
Xanomeline High Dose		Week 16	64.0	70.0	-6.0
Xanomeline High Dose		Week 16	62.0	72.0	-10.0
Xanomeline High Dose		Week 2	70.0	60.0	10.0
Xanomeline High Dose		Week 2	76.0	70.0	6.0
Xanomeline High Dose		Week 2	74.0	72.0	2.0
Xanomeline High Dose		Week 20	70.0	60.0	10.0
Xanomeline High Dose		Week 20	68.0	70.0	-2.0
Xanomeline High Dose		Week 20	70.0	72.0	-2.0
Xanomeline High Dose		Week 24	60.0	60.0	0.0
Xanomeline High Dose		Week 24	80.0	70.0	10.0
Xanomeline High Dose		Week 24	80.0	72.0	8.0
Xanomeline High Dose		Week 26	80.0	60.0	20.0
Xanomeline High Dose		Week 26	80.0	70.0	10.0
Xanomeline High Dose		Week 26	78.0	72.0	6.0
Xanomeline High Dose		Week 4	70.0	60.0	10.0
Xanomeline High Dose		Week 4	70.0	70.0	0.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 6	68.0	60.0	8.0
Xanomeline High Dose		Week 6	64.0	70.0	-6.0
Xanomeline High Dose		Week 6	68.0	72.0	-4.0
Xanomeline High Dose		Week 8	64.0	60.0	4.0
Xanomeline High Dose		Week 8	76.0	70.0	6.0
Xanomeline High Dose		Week 8	70.0	72.0	-2.0
Xanomeline High Dose			66.0	60.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			74.0	72.0
Xanomeline High Dose			66.0	60.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			78.0	72.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	70.0	90.0	-20.0
Placebo		Week 12	75.0	88.0	-13.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	80.0	90.0	-10.0
Placebo		Week 16	84.0	88.0	-4.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	74.0	90.0	-16.0
Placebo		Week 2	72.0	88.0	-16.0
Placebo		Week 4	76.0	80.0	-4.0
Placebo		Week 4	74.0	90.0	-16.0
Placebo		Week 4	76.0	88.0	-12.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	70.0	90.0	-20.0
Placebo		Week 6	76.0	88.0	-12.0
Placebo		Week 8	68.0	80.0	-12.0
Placebo		Week 8	70.0	90.0	-20.0
Placebo		Week 8	72.0	88.0	-16.0
Placebo			90.0	80.0
Placebo			80.0	90.0
Placebo			82.0	88.0
Placebo			72.0	80.0
Placebo			76.0	90.0
Placebo			78.0	88.0
Xanomeline Low Dose		Week 2	85.0	84.0	1.0
Xanomeline Low Dose		Week 2	94.0	90.0	4.0
Xanomeline Low Dose		Week 2	90.0	88.0	2.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	80.0	86.0	-6.0
Placebo		Week 2	84.0	84.0	0.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	88.0	86.0	2.0
Placebo		Week 4	86.0	84.0	2.0
Placebo		Week 6	82.0	80.0	2.0
Placebo		Week 6	84.0	86.0	-2.0
Placebo		Week 6	80.0	84.0	-4.0
Placebo			78.0	80.0
Placebo			76.0	86.0
Placebo			78.0	84.0
Placebo			70.0	80.0
Placebo			68.0	86.0
Placebo			70.0	84.0
Xanomeline High Dose		Week 2	72.0	74.0	-2.0
Xanomeline High Dose		Week 2	70.0	90.0	-20.0
Xanomeline High Dose		Week 2	74.0	82.0	-8.0
Xanomeline High Dose		Week 4	68.0	74.0	-6.0
Xanomeline High Dose		Week 4	80.0	90.0	-10.0
Xanomeline High Dose		Week 4	70.0	82.0	-12.0
Xanomeline High Dose		Week 6	88.0	74.0	14.0
Xanomeline High Dose		Week 6	90.0	90.0	0.0
Xanomeline High Dose		Week 6	86.0	82.0	4.0
Xanomeline High Dose		Week 8	84.0	74.0	10.0
Xanomeline High Dose		Week 8	90.0	90.0	0.0
Xanomeline High Dose		Week 8	88.0	82.0	6.0
Xanomeline High Dose			90.0	74.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			92.0	82.0
Xanomeline High Dose			80.0	74.0
Xanomeline High Dose			86.0	90.0
Xanomeline High Dose			84.0	82.0
Xanomeline Low Dose		Week 2	70.0	74.0	-4.0
Xanomeline Low Dose		Week 2	86.0	80.0	6.0
Xanomeline Low Dose		Week 2	82.0	78.0	4.0
Xanomeline Low Dose		Week 4	82.0	74.0	8.0
Xanomeline Low Dose		Week 4	86.0	80.0	6.0
Xanomeline Low Dose		Week 4	84.0	78.0	6.0
Xanomeline Low Dose		Week 6	76.0	74.0	2.0
Xanomeline Low Dose		Week 6	72.0	80.0	-8.0
Xanomeline Low Dose		Week 6	74.0	78.0	-4.0
Xanomeline Low Dose		Week 8	90.0	74.0	16.0
Xanomeline Low Dose		Week 8	98.0	80.0	18.0
Xanomeline Low Dose		Week 8	96.0	78.0	18.0
Xanomeline Low Dose			82.0	74.0
Xanomeline Low Dose			82.0	80.0
Xanomeline Low Dose			84.0	78.0
Xanomeline Low Dose			80.0	74.0
Xanomeline Low Dose			88.0	80.0
Xanomeline Low Dose			90.0	78.0
Placebo		Week 2	52.0	60.0	-8.0
Placebo		Week 2	60.0	70.0	-10.0
Placebo		Week 2	56.0	68.0	-12.0
Placebo		Week 4	66.0	60.0	6.0
Placebo		Week 4	68.0	70.0	-2.0
Placebo		Week 4	68.0	68.0	0.0
Placebo			50.0	60.0
Placebo			52.0	70.0
Placebo			56.0	68.0
Placebo		Week 12	98.0	98.0	0.0
Placebo		Week 12	98.0	98.0	0.0
Placebo		Week 12	98.0	96.0	2.0
Placebo		Week 16	98.0	98.0	0.0
Placebo		Week 16	98.0	98.0	0.0
Placebo		Week 16	96.0	96.0	0.0
Placebo		Week 2	96.0	98.0	-2.0
Placebo		Week 2	98.0	98.0	0.0
Placebo		Week 2	96.0	96.0	0.0
Placebo		Week 4	90.0	98.0	-8.0
Placebo		Week 4	94.0	98.0	-4.0
Placebo		Week 4	92.0	96.0	-4.0
Placebo		Week 6	98.0	98.0	0.0
Placebo		Week 6	92.0	98.0	-6.0
Placebo		Week 6	94.0	96.0	-2.0
Placebo		Week 8	98.0	98.0	0.0
Placebo		Week 8	96.0	98.0	-2.0
Placebo		Week 8	98.0	96.0	2.0
Placebo			98.0	98.0
Placebo			96.0	98.0
Placebo			98.0	96.0
Placebo			98.0	98.0
Placebo			98.0	98.0
Placebo			98.0	96.0
Xanomeline High Dose		Week 12	70.0	88.0	-18.0
Xanomeline High Dose		Week 12	80.0	86.0	-6.0
Xanomeline High Dose		Week 12	78.0	84.0	-6.0
Xanomeline High Dose		Week 16	90.0	88.0	2.0
Xanomeline High Dose		Week 16	88.0	86.0	2.0
Xanomeline High Dose		Week 16	90.0	84.0	6.0
Xanomeline High Dose		Week 2	90.0	88.0	2.0
Xanomeline High Dose		Week 2	90.0	86.0	4.0
Xanomeline High Dose		Week 2	88.0	84.0	4.0
Xanomeline High Dose		Week 20	92.0	88.0	4.0
Xanomeline High Dose		Week 20	92.0	86.0	6.0
Xanomeline High Dose		Week 20	90.0	84.0	6.0
Xanomeline High Dose		Week 24	80.0	88.0	-8.0
Xanomeline High Dose		Week 24	78.0	86.0	-8.0
Xanomeline High Dose		Week 24	80.0	84.0	-4.0
Xanomeline High Dose		Week 26	80.0	88.0	-8.0
Xanomeline High Dose		Week 26	82.0	86.0	-4.0
Xanomeline High Dose		Week 26	80.0	84.0	-4.0
Xanomeline High Dose		Week 4	86.0	88.0	-2.0
Xanomeline High Dose		Week 4	88.0	86.0	2.0
Xanomeline High Dose		Week 4	86.0	84.0	2.0
Xanomeline High Dose		Week 6	90.0	88.0	2.0
Xanomeline High Dose		Week 6	80.0	86.0	-6.0
Xanomeline High Dose		Week 6	86.0	84.0	2.0
Xanomeline High Dose		Week 8	90.0	88.0	2.0
Xanomeline High Dose		Week 8	88.0	86.0	2.0
Xanomeline High Dose		Week 8	92.0	84.0	8.0
Xanomeline High Dose			80.0	88.0
Xanomeline High Dose			84.0	86.0
Xanomeline High Dose			82.0	84.0
Xanomeline High Dose			86.0	88.0
Xanomeline High Dose			90.0	86.0
Xanomeline High Dose			88.0	84.0
Xanomeline Low Dose		Week 12	80.0	80.0	0.0
Xanomeline Low Dose		Week 12	90.0	80.0	10.0
Xanomeline Low Dose		Week 12	88.0	76.0	12.0
Xanomeline Low Dose		Week 16	80.0	80.0	0.0
Xanomeline Low Dose		Week 16	86.0	80.0	6.0
Xanomeline Low Dose		Week 16	84.0	76.0	8.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	72.0	76.0	-4.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 20	78.0	76.0	2.0
Xanomeline Low Dose		Week 4	72.0	80.0	-8.0
Xanomeline Low Dose		Week 4	76.0	80.0	-4.0
Xanomeline Low Dose		Week 4	78.0	76.0	2.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	86.0	80.0	6.0
Xanomeline Low Dose		Week 6	84.0	76.0	8.0
Xanomeline Low Dose		Week 8	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	90.0	80.0	10.0
Xanomeline Low Dose		Week 8	88.0	76.0	12.0
Xanomeline Low Dose			76.0	80.0
Xanomeline Low Dose			78.0	80.0
Xanomeline Low Dose			76.0	76.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			86.0	80.0
Xanomeline Low Dose			84.0	76.0
Placebo		Week 12	60.0	84.0	-24.0
Placebo		Week 12	60.0	80.0	-20.0
Placebo		Week 12	62.0	84.0	-22.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	72.0	84.0	-12.0
Placebo		Week 2	70.0	84.0	-14.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	74.0	84.0	-10.0
Placebo		Week 20	70.0	84.0	-14.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 20	70.0	84.0	-14.0
Placebo		Week 24	70.0	84.0	-14.0
Placebo		Week 24	78.0	80.0	-2.0
Placebo		Week 24	76.0	84.0	-8.0
Placebo		Week 26	80.0	84.0	-4.0
Placebo		Week 26	82.0	80.0	2.0
Placebo		Week 26	80.0	84.0	-4.0
Placebo		Week 4	62.0	84.0	-22.0
Placebo		Week 4	60.0	80.0	-20.0
Placebo		Week 4	60.0	84.0	-24.0
Placebo		Week 6	70.0	84.0	-14.0
Placebo		Week 6	70.0	80.0	-10.0
Placebo		Week 6	74.0	84.0	-10.0
Placebo		Week 8	74.0	84.0	-10.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	72.0	84.0	-12.0
Placebo			72.0	84.0
Placebo			70.0	80.0
Placebo			74.0	84.0
Placebo			66.0	84.0
Placebo			70.0	80.0
Placebo			68.0	84.0
Xanomeline Low Dose		Week 12	90.0	100.0	-10.0
Xanomeline Low Dose		Week 12	94.0	98.0	-4.0
Xanomeline Low Dose		Week 12	92.0	100.0	-8.0
Xanomeline Low Dose		Week 16	80.0	100.0	-20.0
Xanomeline Low Dose		Week 16	88.0	98.0	-10.0
Xanomeline Low Dose		Week 16	86.0	100.0	-14.0
Xanomeline Low Dose		Week 2	90.0	100.0	-10.0
Xanomeline Low Dose		Week 2	98.0	98.0	0.0
Xanomeline Low Dose		Week 2	94.0	100.0	-6.0
Xanomeline Low Dose		Week 4	90.0	100.0	-10.0
Xanomeline Low Dose		Week 4	98.0	98.0	0.0
Xanomeline Low Dose		Week 4	96.0	100.0	-4.0
Xanomeline Low Dose		Week 6	98.0	100.0	-2.0
Xanomeline Low Dose		Week 6	100.0	98.0	2.0
Xanomeline Low Dose		Week 6	98.0	100.0	-2.0
Xanomeline Low Dose		Week 8	82.0	100.0	-18.0
Xanomeline Low Dose		Week 8	88.0	98.0	-10.0
Xanomeline Low Dose		Week 8	88.0	100.0	-12.0
Xanomeline Low Dose			100.0	100.0
Xanomeline Low Dose			98.0	98.0
Xanomeline Low Dose			96.0	100.0
Xanomeline Low Dose			90.0	100.0
Xanomeline Low Dose			96.0	98.0
Xanomeline Low Dose			92.0	100.0
Xanomeline High Dose		Week 12	86.0	98.0	-12.0
Xanomeline High Dose		Week 12	90.0	98.0	-8.0
Xanomeline High Dose		Week 12	88.0	96.0	-8.0
Xanomeline High Dose		Week 16	80.0	98.0	-18.0
Xanomeline High Dose		Week 16	84.0	98.0	-14.0
Xanomeline High Dose		Week 16	78.0	96.0	-18.0
Xanomeline High Dose		Week 2	60.0	98.0	-38.0
Xanomeline High Dose		Week 2	68.0	98.0	-30.0
Xanomeline High Dose		Week 2	64.0	96.0	-32.0
Xanomeline High Dose		Week 20	90.0	98.0	-8.0
Xanomeline High Dose		Week 20	90.0	98.0	-8.0
Xanomeline High Dose		Week 20	92.0	96.0	-4.0
Xanomeline High Dose		Week 24	80.0	98.0	-18.0
Xanomeline High Dose		Week 24	90.0	98.0	-8.0
Xanomeline High Dose		Week 24	88.0	96.0	-8.0
Xanomeline High Dose		Week 26	80.0	98.0	-18.0
Xanomeline High Dose		Week 26	80.0	98.0	-18.0
Xanomeline High Dose		Week 26	82.0	96.0	-14.0
Xanomeline High Dose		Week 4	66.0	98.0	-32.0
Xanomeline High Dose		Week 4	70.0	98.0	-28.0
Xanomeline High Dose		Week 4	68.0	96.0	-28.0
Xanomeline High Dose		Week 6	82.0	98.0	-16.0
Xanomeline High Dose		Week 6	80.0	98.0	-18.0
Xanomeline High Dose		Week 6	84.0	96.0	-12.0
Xanomeline High Dose		Week 8	90.0	98.0	-8.0
Xanomeline High Dose		Week 8	90.0	98.0	-8.0
Xanomeline High Dose		Week 8	92.0	96.0	-4.0
Xanomeline High Dose			72.0	98.0
Xanomeline High Dose			80.0	98.0
Xanomeline High Dose			80.0	96.0
Xanomeline High Dose			74.0	98.0
Xanomeline High Dose			80.0	98.0
Xanomeline High Dose			78.0	96.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	74.0	78.0	-4.0
Xanomeline High Dose		Week 2	78.0	82.0	-4.0
Xanomeline High Dose			74.0	80.0
Xanomeline High Dose			68.0	78.0
Xanomeline High Dose			74.0	82.0
Placebo		Week 12	70.0	72.0	-2.0
Placebo		Week 12	68.0	74.0	-6.0
Placebo		Week 12	70.0	70.0	0.0
Placebo		Week 16	66.0	72.0	-6.0
Placebo		Week 16	68.0	74.0	-6.0
Placebo		Week 16	70.0	70.0	0.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 2	64.0	74.0	-10.0
Placebo		Week 2	64.0	70.0	-6.0
Placebo		Week 20	76.0	72.0	4.0
Placebo		Week 20	70.0	74.0	-4.0
Placebo		Week 20	70.0	70.0	0.0
Placebo		Week 24	76.0	72.0	4.0
Placebo		Week 24	78.0	74.0	4.0
Placebo		Week 24	74.0	70.0	4.0
Placebo		Week 26	76.0	72.0	4.0
Placebo		Week 26	70.0	74.0	-4.0
Placebo		Week 26	62.0	70.0	-8.0
Placebo		Week 4	66.0	72.0	-6.0
Placebo		Week 4	62.0	74.0	-12.0
Placebo		Week 4	66.0	70.0	-4.0
Placebo		Week 6	76.0	72.0	4.0
Placebo		Week 6	74.0	74.0	0.0
Placebo		Week 6	72.0	70.0	2.0
Placebo		Week 8	74.0	72.0	2.0
Placebo		Week 8	70.0	74.0	-4.0
Placebo		Week 8	70.0	70.0	0.0
Placebo			62.0	72.0
Placebo			66.0	74.0
Placebo			66.0	70.0
Placebo			66.0	72.0
Placebo			60.0	74.0
Placebo			60.0	70.0
Xanomeline Low Dose		Week 2	70.0	76.0	-6.0
Xanomeline Low Dose		Week 2	74.0	72.0	2.0
Xanomeline Low Dose		Week 2	74.0	72.0	2.0
Xanomeline Low Dose		Week 4	80.0	76.0	4.0
Xanomeline Low Dose		Week 4	72.0	72.0	0.0
Xanomeline Low Dose		Week 4	72.0	72.0	0.0
Xanomeline Low Dose		Week 6	78.0	76.0	2.0
Xanomeline Low Dose		Week 6	76.0	72.0	4.0
Xanomeline Low Dose		Week 6	76.0	72.0	4.0
Xanomeline Low Dose		Week 8	72.0	76.0	-4.0
Xanomeline Low Dose		Week 8	76.0	72.0	4.0
Xanomeline Low Dose		Week 8	74.0	72.0	2.0
Xanomeline Low Dose			68.0	76.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose			70.0	76.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			62.0	72.0
Xanomeline Low Dose		Week 12	60.0	60.0	0.0
Xanomeline Low Dose		Week 12	70.0	60.0	10.0
Xanomeline Low Dose		Week 12	60.0	70.0	-10.0
Xanomeline Low Dose		Week 16	60.0	60.0	0.0
Xanomeline Low Dose		Week 16	60.0	60.0	0.0
Xanomeline Low Dose		Week 16	60.0	70.0	-10.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	60.0	70.0	-10.0
Xanomeline Low Dose		Week 20	71.0	60.0	11.0
Xanomeline Low Dose		Week 20	70.0	60.0	10.0
Xanomeline Low Dose		Week 20	80.0	70.0	10.0
Xanomeline Low Dose		Week 24	70.0	60.0	10.0
Xanomeline Low Dose		Week 24	60.0	60.0	0.0
Xanomeline Low Dose		Week 24	70.0	70.0	0.0
Xanomeline Low Dose		Week 26	60.0	60.0	0.0
Xanomeline Low Dose		Week 26	60.0	60.0	0.0
Xanomeline Low Dose		Week 26	58.0	70.0	-12.0
Xanomeline Low Dose		Week 4	60.0	60.0	0.0
Xanomeline Low Dose		Week 4	50.0	60.0	-10.0
Xanomeline Low Dose		Week 4	60.0	70.0	-10.0
Xanomeline Low Dose		Week 6	50.0	60.0	-10.0
Xanomeline Low Dose		Week 6	60.0	60.0	0.0
Xanomeline Low Dose		Week 6	60.0	70.0	-10.0
Xanomeline Low Dose		Week 8	70.0	60.0	10.0
Xanomeline Low Dose		Week 8	60.0	60.0	0.0
Xanomeline Low Dose		Week 8	60.0	70.0	-10.0
Xanomeline Low Dose			50.0	60.0
Xanomeline Low Dose			50.0	60.0
Xanomeline Low Dose			60.0	70.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			70.0	60.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose		Week 12	90.0	90.0	0.0
Xanomeline Low Dose		Week 12	90.0	90.0	0.0
Xanomeline Low Dose		Week 12	90.0	100.0	-10.0
Xanomeline Low Dose		Week 16	85.0	90.0	-5.0
Xanomeline Low Dose		Week 16	80.0	90.0	-10.0
Xanomeline Low Dose		Week 16	90.0	100.0	-10.0
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	90.0	100.0	-10.0
Xanomeline Low Dose		Week 20	71.0	90.0	-19.0
Xanomeline Low Dose		Week 20	70.0	90.0	-20.0
Xanomeline Low Dose		Week 20	70.0	100.0	-30.0
Xanomeline Low Dose		Week 24	90.0	90.0	0.0
Xanomeline Low Dose		Week 24	90.0	90.0	0.0
Xanomeline Low Dose		Week 24	90.0	100.0	-10.0
Xanomeline Low Dose		Week 26	90.0	90.0	0.0
Xanomeline Low Dose		Week 26	90.0	90.0	0.0
Xanomeline Low Dose		Week 26	90.0	100.0	-10.0
Xanomeline Low Dose		Week 4	100.0	90.0	10.0
Xanomeline Low Dose		Week 4	95.0	90.0	5.0
Xanomeline Low Dose		Week 4	95.0	100.0	-5.0
Xanomeline Low Dose		Week 6	92.0	90.0	2.0
Xanomeline Low Dose		Week 6	90.0	90.0	0.0
Xanomeline Low Dose		Week 6	90.0	100.0	-10.0
Xanomeline Low Dose		Week 8	90.0	90.0	0.0
Xanomeline Low Dose		Week 8	90.0	90.0	0.0
Xanomeline Low Dose		Week 8	90.0	100.0	-10.0
Xanomeline Low Dose			60.0	90.0
Xanomeline Low Dose			70.0	90.0
Xanomeline Low Dose			70.0	100.0
Xanomeline High Dose		Week 12	70.0	60.0	10.0
Xanomeline High Dose		Week 12	70.0	60.0	10.0
Xanomeline High Dose		Week 12	60.0	60.0	0.0
Xanomeline High Dose		Week 16	50.0	60.0	-10.0
Xanomeline High Dose		Week 16	60.0	60.0	0.0
Xanomeline High Dose		Week 16	60.0	60.0	0.0
Xanomeline High Dose		Week 2	70.0	60.0	10.0
Xanomeline High Dose		Week 2	70.0	60.0	10.0
Xanomeline High Dose		Week 2	70.0	60.0	10.0
Xanomeline High Dose		Week 20	60.0	60.0	0.0
Xanomeline High Dose		Week 20	60.0	60.0	0.0
Xanomeline High Dose		Week 20	60.0	60.0	0.0
Xanomeline High Dose		Week 24	60.0	60.0	0.0
Xanomeline High Dose		Week 24	50.0	60.0	-10.0
Xanomeline High Dose		Week 24	50.0	60.0	-10.0
Xanomeline High Dose		Week 26	50.0	60.0	-10.0
Xanomeline High Dose		Week 26	50.0	60.0	-10.0
Xanomeline High Dose		Week 26	50.0	60.0	-10.0
Xanomeline High Dose		Week 4	70.0	60.0	10.0
Xanomeline High Dose		Week 4	70.0	60.0	10.0
Xanomeline High Dose		Week 4	70.0	60.0	10.0
Xanomeline High Dose		Week 6	70.0	60.0	10.0
Xanomeline High Dose		Week 6	70.0	60.0	10.0
Xanomeline High Dose		Week 6	70.0	60.0	10.0
Xanomeline High Dose		Week 8	60.0	60.0	0.0
Xanomeline High Dose		Week 8	60.0	60.0	0.0
Xanomeline High Dose		Week 8	60.0	60.0	0.0
Xanomeline High Dose			60.0	60.0
Xanomeline High Dose			70.0	60.0
Xanomeline High Dose			60.0	60.0
Xanomeline High Dose			60.0	60.0
Xanomeline High Dose			70.0	60.0
Xanomeline High Dose			70.0	60.0
Xanomeline High Dose		Week 2	70.0	70.0	0.0
Xanomeline High Dose		Week 2	70.0	60.0	10.0
Xanomeline High Dose		Week 2	70.0	80.0	-10.0
Xanomeline High Dose		Week 4	64.0	70.0	-6.0
Xanomeline High Dose		Week 4	60.0	60.0	0.0
Xanomeline High Dose		Week 4	60.0	80.0	-20.0
Xanomeline High Dose			68.0	70.0
Xanomeline High Dose			68.0	60.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			60.0	70.0
Xanomeline High Dose			60.0	60.0
Xanomeline High Dose			50.0	80.0
Placebo		Week 12	70.0	70.0	0.0
Placebo		Week 12	80.0	70.0	10.0
Placebo		Week 12	80.0	70.0	10.0
Placebo		Week 16	90.0	70.0	20.0
Placebo		Week 16	80.0	70.0	10.0
Placebo		Week 16	80.0	70.0	10.0
Placebo		Week 2	70.0	70.0	0.0
Placebo		Week 2	80.0	70.0	10.0
Placebo		Week 2	90.0	70.0	20.0
Placebo		Week 20	70.0	70.0	0.0
Placebo		Week 20	70.0	70.0	0.0
Placebo		Week 20	80.0	70.0	10.0
Placebo		Week 24	60.0	70.0	-10.0
Placebo		Week 24	80.0	70.0	10.0
Placebo		Week 24	80.0	70.0	10.0
Placebo		Week 26	60.0	70.0	-10.0
Placebo		Week 26	80.0	70.0	10.0
Placebo		Week 26	60.0	70.0	-10.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 4	60.0	70.0	-10.0
Placebo		Week 4	70.0	70.0	0.0
Placebo		Week 6	70.0	70.0	0.0
Placebo		Week 6	90.0	70.0	20.0
Placebo		Week 6	80.0	70.0	10.0
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	70.0	70.0	0.0
Placebo			70.0	70.0
Placebo			80.0	70.0
Placebo			60.0	70.0
Placebo			60.0	70.0
Placebo			90.0	70.0
Placebo			70.0	70.0
Xanomeline High Dose		Week 12	60.0	70.0	-10.0
Xanomeline High Dose		Week 12	60.0	70.0	-10.0
Xanomeline High Dose		Week 12	60.0	80.0	-20.0
Xanomeline High Dose		Week 16	80.0	70.0	10.0
Xanomeline High Dose		Week 16	80.0	70.0	10.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 2	60.0	70.0	-10.0
Xanomeline High Dose		Week 2	60.0	70.0	-10.0
Xanomeline High Dose		Week 2	60.0	80.0	-20.0
Xanomeline High Dose		Week 20	70.0	70.0	0.0
Xanomeline High Dose		Week 20	70.0	70.0	0.0
Xanomeline High Dose		Week 20	70.0	80.0	-10.0
Xanomeline High Dose		Week 24	70.0	70.0	0.0
Xanomeline High Dose		Week 24	70.0	70.0	0.0
Xanomeline High Dose		Week 24	70.0	80.0	-10.0
Xanomeline High Dose		Week 26	60.0	70.0	-10.0
Xanomeline High Dose		Week 26	70.0	70.0	0.0
Xanomeline High Dose		Week 26	60.0	80.0	-20.0
Xanomeline High Dose		Week 4	70.0	70.0	0.0
Xanomeline High Dose		Week 4	70.0	70.0	0.0
Xanomeline High Dose		Week 4	70.0	80.0	-10.0
Xanomeline High Dose		Week 6	60.0	70.0	-10.0
Xanomeline High Dose		Week 6	60.0	70.0	-10.0
Xanomeline High Dose		Week 6	60.0	80.0	-20.0
Xanomeline High Dose		Week 8	80.0	70.0	10.0
Xanomeline High Dose		Week 8	60.0	70.0	-10.0
Xanomeline High Dose		Week 8	60.0	80.0	-20.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			74.0	70.0
Xanomeline High Dose			78.0	70.0
Xanomeline High Dose			80.0	80.0
Placebo		Week 12	60.0	60.0	0.0
Placebo		Week 12	66.0	56.0	10.0
Placebo		Week 12	60.0	54.0	6.0
Placebo		Week 16	50.0	60.0	-10.0
Placebo		Week 16	50.0	56.0	-6.0
Placebo		Week 16	50.0	54.0	-4.0
Placebo		Week 2	60.0	60.0	0.0
Placebo		Week 2	70.0	56.0	14.0
Placebo		Week 2	60.0	54.0	6.0
Placebo		Week 20	60.0	60.0	0.0
Placebo		Week 20	60.0	56.0	4.0
Placebo		Week 20	60.0	54.0	6.0
Placebo		Week 24	60.0	60.0	0.0
Placebo		Week 24	60.0	56.0	4.0
Placebo		Week 24	60.0	54.0	6.0
Placebo		Week 26	60.0	60.0	0.0
Placebo		Week 26	50.0	56.0	-6.0
Placebo		Week 26	60.0	54.0	6.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 4	60.0	56.0	4.0
Placebo		Week 4	60.0	54.0	6.0
Placebo		Week 6	60.0	60.0	0.0
Placebo		Week 6	60.0	56.0	4.0
Placebo		Week 6	60.0	54.0	6.0
Placebo		Week 8	60.0	60.0	0.0
Placebo		Week 8	50.0	56.0	-6.0
Placebo		Week 8	60.0	54.0	6.0
Placebo			60.0	60.0
Placebo			56.0	56.0
Placebo			60.0	54.0
Placebo			66.0	60.0
Placebo			60.0	56.0
Placebo			60.0	54.0
Placebo		Week 12	80.0	60.0	20.0
Placebo		Week 12	70.0	60.0	10.0
Placebo		Week 12	76.0	60.0	16.0
Placebo		Week 16	70.0	60.0	10.0
Placebo		Week 16	70.0	60.0	10.0
Placebo		Week 16	80.0	60.0	20.0
Placebo		Week 2	90.0	60.0	30.0
Placebo		Week 2	80.0	60.0	20.0
Placebo		Week 2	75.0	60.0	15.0
Placebo		Week 20	70.0	60.0	10.0
Placebo		Week 20	70.0	60.0	10.0
Placebo		Week 20	70.0	60.0	10.0
Placebo		Week 24	80.0	60.0	20.0
Placebo		Week 24	80.0	60.0	20.0
Placebo		Week 24	70.0	60.0	10.0
Placebo		Week 26	70.0	60.0	10.0
Placebo		Week 26	70.0	60.0	10.0
Placebo		Week 26	70.0	60.0	10.0
Placebo		Week 4	90.0	60.0	30.0
Placebo		Week 4	90.0	60.0	30.0
Placebo		Week 4	90.0	60.0	30.0
Placebo		Week 6	70.0	60.0	10.0
Placebo		Week 6	80.0	60.0	20.0
Placebo		Week 6	75.0	60.0	15.0
Placebo		Week 8	70.0	60.0	10.0
Placebo		Week 8	80.0	60.0	20.0
Placebo		Week 8	80.0	60.0	20.0
Placebo			70.0	60.0
Placebo			71.0	60.0
Placebo			71.0	60.0
Xanomeline Low Dose		Week 12	90.0	70.0	20.0
Xanomeline Low Dose		Week 12	90.0	70.0	20.0
Xanomeline Low Dose		Week 12	90.0	70.0	20.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 2	80.0	70.0	10.0
Xanomeline Low Dose		Week 2	80.0	70.0	10.0
Xanomeline Low Dose		Week 4	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	75.0	70.0	5.0
Xanomeline Low Dose		Week 4	80.0	70.0	10.0
Xanomeline Low Dose		Week 6	80.0	70.0	10.0
Xanomeline Low Dose		Week 6	80.0	70.0	10.0
Xanomeline Low Dose		Week 6	80.0	70.0	10.0
Xanomeline Low Dose		Week 8	90.0	70.0	20.0
Xanomeline Low Dose		Week 8	90.0	70.0	20.0
Xanomeline Low Dose		Week 8	80.0	70.0	10.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			80.0	70.0
Xanomeline Low Dose			80.0	70.0
Xanomeline Low Dose			80.0	70.0
Placebo		Week 12	76.0	72.0	4.0
Placebo		Week 12	76.0	74.0	2.0
Placebo		Week 12	76.0	72.0	4.0
Placebo		Week 16	86.0	72.0	14.0
Placebo		Week 16	78.0	74.0	4.0
Placebo		Week 16	80.0	72.0	8.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	76.0	74.0	2.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 20	74.0	72.0	2.0
Placebo		Week 20	72.0	74.0	-2.0
Placebo		Week 20	68.0	72.0	-4.0
Placebo		Week 24	72.0	72.0	0.0
Placebo		Week 24	68.0	74.0	-6.0
Placebo		Week 24	66.0	72.0	-6.0
Placebo		Week 26	74.0	72.0	2.0
Placebo		Week 26	70.0	74.0	-4.0
Placebo		Week 26	66.0	72.0	-6.0
Placebo		Week 4	78.0	72.0	6.0
Placebo		Week 4	80.0	74.0	6.0
Placebo		Week 4	80.0	72.0	8.0
Placebo		Week 6	74.0	72.0	2.0
Placebo		Week 6	72.0	74.0	-2.0
Placebo		Week 6	70.0	72.0	-2.0
Placebo		Week 8	70.0	72.0	-2.0
Placebo		Week 8	70.0	74.0	-4.0
Placebo		Week 8	74.0	72.0	2.0
Placebo			72.0	72.0
Placebo			76.0	74.0
Placebo			72.0	72.0
Placebo			80.0	72.0
Placebo			76.0	74.0
Placebo			74.0	72.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	72.0	80.0	-8.0
Xanomeline Low Dose		Week 2	70.0	78.0	-8.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	78.0	78.0	0.0
Xanomeline Low Dose		Week 6	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	82.0	80.0	2.0
Xanomeline Low Dose		Week 6	78.0	78.0	0.0
Xanomeline Low Dose		Week 8	78.0	80.0	-2.0
Xanomeline Low Dose		Week 8	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	80.0	78.0	2.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose		Week 12	86.0	74.0	12.0
Xanomeline Low Dose		Week 12	74.0	80.0	-6.0
Xanomeline Low Dose		Week 12	80.0	78.0	2.0
Xanomeline Low Dose		Week 16	84.0	74.0	10.0
Xanomeline Low Dose		Week 16	90.0	80.0	10.0
Xanomeline Low Dose		Week 16	94.0	78.0	16.0
Xanomeline Low Dose		Week 2	78.0	74.0	4.0
Xanomeline Low Dose		Week 2	84.0	80.0	4.0
Xanomeline Low Dose		Week 2	88.0	78.0	10.0
Xanomeline Low Dose		Week 20	70.0	74.0	-4.0
Xanomeline Low Dose		Week 20	76.0	80.0	-4.0
Xanomeline Low Dose		Week 20	72.0	78.0	-6.0
Xanomeline Low Dose		Week 24	78.0	74.0	4.0
Xanomeline Low Dose		Week 24	70.0	80.0	-10.0
Xanomeline Low Dose		Week 24	68.0	78.0	-10.0
Xanomeline Low Dose		Week 26	76.0	74.0	2.0
Xanomeline Low Dose		Week 26	78.0	80.0	-2.0
Xanomeline Low Dose		Week 26	76.0	78.0	-2.0
Xanomeline Low Dose		Week 4	70.0	74.0	-4.0
Xanomeline Low Dose		Week 4	70.0	80.0	-10.0
Xanomeline Low Dose		Week 4	72.0	78.0	-6.0
Xanomeline Low Dose		Week 6	78.0	74.0	4.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	78.0	78.0	0.0
Xanomeline Low Dose		Week 8	68.0	74.0	-6.0
Xanomeline Low Dose		Week 8	66.0	80.0	-14.0
Xanomeline Low Dose		Week 8	68.0	78.0	-10.0
Xanomeline High Dose		Week 12	76.0	88.0	-12.0
Xanomeline High Dose		Week 12	74.0	88.0	-14.0
Xanomeline High Dose		Week 12	78.0	94.0	-16.0
Xanomeline High Dose		Week 16	76.0	88.0	-12.0
Xanomeline High Dose		Week 16	76.0	88.0	-12.0
Xanomeline High Dose		Week 16	72.0	94.0	-22.0
Xanomeline High Dose		Week 2	72.0	88.0	-16.0
Xanomeline High Dose		Week 2	80.0	88.0	-8.0
Xanomeline High Dose		Week 2	70.0	94.0	-24.0
Xanomeline High Dose		Week 20	74.0	88.0	-14.0
Xanomeline High Dose		Week 20	74.0	88.0	-14.0
Xanomeline High Dose		Week 20	80.0	94.0	-14.0
Xanomeline High Dose		Week 24	78.0	88.0	-10.0
Xanomeline High Dose		Week 24	76.0	88.0	-12.0
Xanomeline High Dose		Week 24	74.0	94.0	-20.0
Xanomeline High Dose		Week 26	68.0	88.0	-20.0
Xanomeline High Dose		Week 26	70.0	88.0	-18.0
Xanomeline High Dose		Week 26	80.0	94.0	-14.0
Xanomeline High Dose		Week 4	70.0	88.0	-18.0
Xanomeline High Dose		Week 4	74.0	88.0	-14.0
Xanomeline High Dose		Week 4	92.0	94.0	-2.0
Xanomeline High Dose		Week 6	78.0	88.0	-10.0
Xanomeline High Dose		Week 6	80.0	88.0	-8.0
Xanomeline High Dose		Week 6	82.0	94.0	-12.0
Xanomeline High Dose		Week 8	68.0	88.0	-20.0
Xanomeline High Dose		Week 8	74.0	88.0	-14.0
Xanomeline High Dose		Week 8	70.0	94.0	-24.0
Xanomeline High Dose			80.0	88.0
Xanomeline High Dose			86.0	88.0
Xanomeline High Dose			84.0	94.0
Placebo		Week 12	74.0	76.0	-2.0
Placebo		Week 12	68.0	68.0	0.0
Placebo		Week 12	70.0	72.0	-2.0
Placebo		Week 16	84.0	76.0	8.0
Placebo		Week 16	70.0	68.0	2.0
Placebo		Week 16	66.0	72.0	-6.0
Placebo		Week 2	74.0	76.0	-2.0
Placebo		Week 2	70.0	68.0	2.0
Placebo		Week 2	68.0	72.0	-4.0
Placebo		Week 20	80.0	76.0	4.0
Placebo		Week 20	74.0	68.0	6.0
Placebo		Week 20	78.0	72.0	6.0
Placebo		Week 24	62.0	76.0	-14.0
Placebo		Week 24	58.0	68.0	-10.0
Placebo		Week 24	68.0	72.0	-4.0
Placebo		Week 26	72.0	76.0	-4.0
Placebo		Week 26	66.0	68.0	-2.0
Placebo		Week 26	60.0	72.0	-12.0
Placebo		Week 4	68.0	76.0	-8.0
Placebo		Week 4	60.0	68.0	-8.0
Placebo		Week 4	68.0	72.0	-4.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 6	68.0	68.0	0.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 8	64.0	76.0	-12.0
Placebo		Week 8	64.0	68.0	-4.0
Placebo		Week 8	64.0	72.0	-8.0
Placebo			80.0	76.0
Placebo			68.0	68.0
Placebo			80.0	72.0
Placebo			72.0	76.0
Placebo			74.0	68.0
Placebo			70.0	72.0
Xanomeline Low Dose		Week 12	89.0	63.0	26.0
Xanomeline Low Dose		Week 12	70.0	62.0	8.0
Xanomeline Low Dose		Week 12	79.0	60.0	19.0
Xanomeline Low Dose		Week 16	60.0	63.0	-3.0
Xanomeline Low Dose		Week 16	58.0	62.0	-4.0
Xanomeline Low Dose		Week 16	58.0	60.0	-2.0
Xanomeline Low Dose		Week 2	67.0	63.0	4.0
Xanomeline Low Dose		Week 2	61.0	62.0	-1.0
Xanomeline Low Dose		Week 2	55.0	60.0	-5.0
Xanomeline Low Dose		Week 20	68.0	63.0	5.0
Xanomeline Low Dose		Week 20	62.0	62.0	0.0
Xanomeline Low Dose		Week 20	80.0	60.0	20.0
Xanomeline Low Dose		Week 24	71.0	63.0	8.0
Xanomeline Low Dose		Week 24	65.0	62.0	3.0
Xanomeline Low Dose		Week 24	68.0	60.0	8.0
Xanomeline Low Dose		Week 26	64.0	63.0	1.0
Xanomeline Low Dose		Week 26	73.0	62.0	11.0
Xanomeline Low Dose		Week 26	59.0	60.0	-1.0
Xanomeline Low Dose		Week 4	80.0	63.0	17.0
Xanomeline Low Dose		Week 4	62.0	62.0	0.0
Xanomeline Low Dose		Week 4	75.0	60.0	15.0
Xanomeline Low Dose		Week 6	72.0	63.0	9.0
Xanomeline Low Dose		Week 6	58.0	62.0	-4.0
Xanomeline Low Dose		Week 6	65.0	60.0	5.0
Xanomeline Low Dose		Week 8	56.0	63.0	-7.0
Xanomeline Low Dose		Week 8	67.0	62.0	5.0
Xanomeline Low Dose		Week 8	58.0	60.0	-2.0
Xanomeline Low Dose			59.0	63.0
Xanomeline Low Dose			67.0	62.0
Xanomeline Low Dose			70.0	60.0
Xanomeline Low Dose			71.0	63.0
Xanomeline Low Dose			59.0	62.0
Xanomeline Low Dose			74.0	60.0
Xanomeline Low Dose		Week 2	75.0	60.0	15.0
Xanomeline Low Dose		Week 2	69.0	70.0	-1.0
Xanomeline Low Dose		Week 2	91.0	66.0	25.0
Xanomeline Low Dose		Week 4	67.0	60.0	7.0
Xanomeline Low Dose		Week 4	66.0	70.0	-4.0
Xanomeline Low Dose		Week 4	76.0	66.0	10.0
Xanomeline Low Dose		Week 6	60.0	60.0	0.0
Xanomeline Low Dose		Week 6	75.0	70.0	5.0
Xanomeline Low Dose		Week 6	69.0	66.0	3.0
Xanomeline Low Dose		Week 8	72.0	60.0	12.0
Xanomeline Low Dose		Week 8	64.0	70.0	-6.0
Xanomeline Low Dose		Week 8	67.0	66.0	1.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			79.0	70.0
Xanomeline Low Dose			79.0	66.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			81.0	70.0
Xanomeline Low Dose			62.0	66.0
Placebo		Week 2	69.0	60.0	9.0
Placebo		Week 2	76.0	72.0	4.0
Placebo		Week 2	78.0	73.0	5.0
Placebo		Week 4	74.0	60.0	14.0
Placebo		Week 4	81.0	72.0	9.0
Placebo		Week 4	68.0	73.0	-5.0
Placebo			65.0	60.0
Placebo			74.0	72.0
Placebo			79.0	73.0
Placebo			62.0	60.0
Placebo			80.0	72.0
Placebo			81.0	73.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	80.0	71.0	9.0
Placebo		Week 12	73.0	78.0	-5.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	77.0	71.0	6.0
Placebo		Week 16	71.0	78.0	-7.0
Placebo		Week 2	71.0	80.0	-9.0
Placebo		Week 2	66.0	71.0	-5.0
Placebo		Week 2	80.0	78.0	2.0
Placebo		Week 20	54.0	80.0	-26.0
Placebo		Week 20	51.0	71.0	-20.0
Placebo		Week 20	51.0	78.0	-27.0
Placebo		Week 24	66.0	80.0	-14.0
Placebo		Week 24	64.0	71.0	-7.0
Placebo		Week 24	86.0	78.0	8.0
Placebo		Week 4	64.0	80.0	-16.0
Placebo		Week 4	78.0	71.0	7.0
Placebo		Week 4	71.0	78.0	-7.0
Placebo		Week 6	64.0	80.0	-16.0
Placebo		Week 6	72.0	71.0	1.0
Placebo		Week 6	64.0	78.0	-14.0
Placebo		Week 8	77.0	80.0	-3.0
Placebo		Week 8	86.0	71.0	15.0
Placebo		Week 8	85.0	78.0	7.0
Placebo			73.0	80.0
Placebo			76.0	71.0
Placebo			79.0	78.0
Placebo			65.0	80.0
Placebo			96.0	71.0
Placebo			63.0	78.0
Xanomeline High Dose		Week 2	71.0	73.0	-2.0
Xanomeline High Dose		Week 2	83.0	68.0	15.0
Xanomeline High Dose		Week 2	81.0	76.0	5.0
Xanomeline High Dose			78.0	73.0
Xanomeline High Dose			85.0	68.0
Xanomeline High Dose			89.0	76.0
Xanomeline High Dose		Week 2	61.0	78.0	-17.0
Xanomeline High Dose		Week 2	68.0	88.0	-20.0
Xanomeline High Dose		Week 2	69.0	68.0	1.0
Xanomeline High Dose		Week 4	75.0	78.0	-3.0
Xanomeline High Dose		Week 4	82.0	88.0	-6.0
Xanomeline High Dose		Week 4	80.0	68.0	12.0
Xanomeline High Dose		Week 6	64.0	78.0	-14.0
Xanomeline High Dose		Week 6	85.0	88.0	-3.0
Xanomeline High Dose		Week 6	75.0	68.0	7.0
Xanomeline High Dose		Week 8	62.0	78.0	-16.0
Xanomeline High Dose		Week 8	73.0	88.0	-15.0
Xanomeline High Dose		Week 8	68.0	68.0	0.0
Xanomeline High Dose			80.0	78.0
Xanomeline High Dose			84.0	88.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			57.0	78.0
Xanomeline High Dose			71.0	88.0
Xanomeline High Dose			71.0	68.0
Placebo		Week 12	56.0	72.0	-16.0
Placebo		Week 12	71.0	85.0	-14.0
Placebo		Week 12	60.0	83.0	-23.0
Placebo		Week 16	63.0	72.0	-9.0
Placebo		Week 16	84.0	85.0	-1.0
Placebo		Week 16	66.0	83.0	-17.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 2	76.0	85.0	-9.0
Placebo		Week 2	71.0	83.0	-12.0
Placebo		Week 20	71.0	72.0	-1.0
Placebo		Week 20	68.0	85.0	-17.0
Placebo		Week 20	60.0	83.0	-23.0
Placebo		Week 24	71.0	72.0	-1.0
Placebo		Week 24	62.0	85.0	-23.0
Placebo		Week 24	68.0	83.0	-15.0
Placebo		Week 4	64.0	72.0	-8.0
Placebo		Week 4	78.0	85.0	-7.0
Placebo		Week 4	76.0	83.0	-7.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	65.0	85.0	-20.0
Placebo		Week 6	79.0	83.0	-4.0
Placebo		Week 8	87.0	72.0	15.0
Placebo		Week 8	69.0	85.0	-16.0
Placebo		Week 8	70.0	83.0	-13.0
Placebo			78.0	72.0
Placebo			76.0	85.0
Placebo			74.0	83.0
Placebo			71.0	72.0
Placebo			76.0	85.0
Placebo			69.0	83.0
Placebo		Week 12	82.0	80.0	2.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 12	82.0	84.0	-2.0
Placebo		Week 16	90.0	80.0	10.0
Placebo		Week 16	86.0	80.0	6.0
Placebo		Week 16	90.0	84.0	6.0
Placebo		Week 2	86.0	80.0	6.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	90.0	84.0	6.0
Placebo		Week 20	90.0	80.0	10.0
Placebo		Week 20	98.0	80.0	18.0
Placebo		Week 20	98.0	84.0	14.0
Placebo		Week 24	62.0	80.0	-18.0
Placebo		Week 24	64.0	80.0	-16.0
Placebo		Week 24	64.0	84.0	-20.0
Placebo		Week 26	78.0	80.0	-2.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 26	80.0	84.0	-4.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 4	72.0	84.0	-12.0
Placebo		Week 6	78.0	80.0	-2.0
Placebo		Week 6	96.0	80.0	16.0
Placebo		Week 6	64.0	84.0	-20.0
Placebo		Week 8	78.0	80.0	-2.0
Placebo		Week 8	92.0	80.0	12.0
Placebo		Week 8	78.0	84.0	-6.0
Placebo			90.0	80.0
Placebo			88.0	80.0
Placebo			90.0	84.0
Placebo			80.0	80.0
Placebo			82.0	80.0
Placebo			80.0	84.0
Placebo		Week 12	90.0	96.0	-6.0
Placebo		Week 12	80.0	104.0	-24.0
Placebo		Week 12	100.0	110.0	-10.0
Placebo		Week 16	80.0	96.0	-16.0
Placebo		Week 16	82.0	104.0	-22.0
Placebo		Week 16	80.0	110.0	-30.0
Placebo		Week 2	80.0	96.0	-16.0
Placebo		Week 2	84.0	104.0	-20.0
Placebo		Week 2	84.0	110.0	-26.0
Placebo		Week 20	90.0	96.0	-6.0
Placebo		Week 20	90.0	104.0	-14.0
Placebo		Week 20	88.0	110.0	-22.0
Placebo		Week 24	98.0	96.0	2.0
Placebo		Week 24	110.0	104.0	6.0
Placebo		Week 24	110.0	110.0	0.0
Placebo		Week 26	90.0	96.0	-6.0
Placebo		Week 26	92.0	104.0	-12.0
Placebo		Week 26	90.0	110.0	-20.0
Placebo		Week 4	88.0	96.0	-8.0
Placebo		Week 4	84.0	104.0	-20.0
Placebo		Week 4	82.0	110.0	-28.0
Placebo		Week 6	100.0	96.0	4.0
Placebo		Week 6	110.0	104.0	6.0
Placebo		Week 6	100.0	110.0	-10.0
Placebo		Week 8	84.0	96.0	-12.0
Placebo		Week 8	90.0	104.0	-14.0
Placebo		Week 8	80.0	110.0	-30.0
Placebo			78.0	96.0
Placebo			104.0	104.0
Placebo			108.0	110.0
Placebo			80.0	96.0
Placebo			82.0	104.0
Placebo			82.0	110.0
Placebo		Week 12	74.0	72.0	2.0
Placebo		Week 12	60.0	74.0	-14.0
Placebo		Week 12	68.0	74.0	-6.0
Placebo		Week 16	84.0	72.0	12.0
Placebo		Week 16	84.0	74.0	10.0
Placebo		Week 16	82.0	74.0	8.0
Placebo		Week 2	86.0	72.0	14.0
Placebo		Week 2	70.0	74.0	-4.0
Placebo		Week 2	70.0	74.0	-4.0
Placebo		Week 20	82.0	72.0	10.0
Placebo		Week 20	84.0	74.0	10.0
Placebo		Week 20	80.0	74.0	6.0
Placebo		Week 24	74.0	72.0	2.0
Placebo		Week 24	70.0	74.0	-4.0
Placebo		Week 24	68.0	74.0	-6.0
Placebo		Week 26	76.0	72.0	4.0
Placebo		Week 26	76.0	74.0	2.0
Placebo		Week 26	74.0	74.0	0.0
Placebo		Week 4	82.0	72.0	10.0
Placebo		Week 4	70.0	74.0	-4.0
Placebo		Week 4	72.0	74.0	-2.0
Placebo		Week 6	86.0	72.0	14.0
Placebo		Week 6	70.0	74.0	-4.0
Placebo		Week 6	74.0	74.0	0.0
Placebo		Week 8	84.0	72.0	12.0
Placebo		Week 8	78.0	74.0	4.0
Placebo		Week 8	80.0	74.0	6.0
Placebo			70.0	72.0
Placebo			62.0	74.0
Placebo			62.0	74.0
Placebo			70.0	72.0
Placebo			60.0	74.0
Placebo			62.0	74.0
Xanomeline Low Dose		Week 12	80.0	100.0	-20.0
Xanomeline Low Dose		Week 12	82.0	80.0	2.0
Xanomeline Low Dose		Week 12	88.0	92.0	-4.0
Xanomeline Low Dose		Week 2	84.0	100.0	-16.0
Xanomeline Low Dose		Week 2	94.0	80.0	14.0
Xanomeline Low Dose		Week 2	98.0	92.0	6.0
Xanomeline Low Dose		Week 4	80.0	100.0	-20.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	84.0	92.0	-8.0
Xanomeline Low Dose		Week 6	80.0	100.0	-20.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	82.0	92.0	-10.0
Xanomeline Low Dose		Week 8	80.0	100.0	-20.0
Xanomeline Low Dose		Week 8	86.0	80.0	6.0
Xanomeline Low Dose		Week 8	100.0	92.0	8.0
Xanomeline Low Dose			90.0	100.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			96.0	92.0
Xanomeline Low Dose			86.0	100.0
Xanomeline Low Dose			102.0	80.0
Xanomeline Low Dose			94.0	92.0
Xanomeline High Dose		Week 2	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	62.0	94.0	-32.0
Xanomeline High Dose		Week 2	74.0	96.0	-22.0
Xanomeline High Dose		Week 4	80.0	90.0	-10.0
Xanomeline High Dose		Week 4	68.0	94.0	-26.0
Xanomeline High Dose		Week 4	80.0	96.0	-16.0
Xanomeline High Dose		Week 6	98.0	90.0	8.0
Xanomeline High Dose		Week 6	90.0	94.0	-4.0
Xanomeline High Dose		Week 6	84.0	96.0	-12.0
Xanomeline High Dose		Week 8	88.0	90.0	-2.0
Xanomeline High Dose		Week 8	96.0	94.0	2.0
Xanomeline High Dose		Week 8	98.0	96.0	2.0
Xanomeline High Dose			92.0	90.0
Xanomeline High Dose			80.0	94.0
Xanomeline High Dose			82.0	96.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			80.0	94.0
Xanomeline High Dose			86.0	96.0
Xanomeline Low Dose		Week 2	60.0	84.0	-24.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 2	72.0	88.0	-16.0
Xanomeline Low Dose		Week 4	70.0	84.0	-14.0
Xanomeline Low Dose		Week 4	70.0	72.0	-2.0
Xanomeline Low Dose		Week 4	70.0	88.0	-18.0
Xanomeline Low Dose			80.0	84.0
Xanomeline Low Dose			80.0	72.0
Xanomeline Low Dose			78.0	88.0
Xanomeline Low Dose			80.0	84.0
Xanomeline Low Dose			60.0	72.0
Xanomeline Low Dose			74.0	88.0
Xanomeline Low Dose		Week 12	70.0	72.0	-2.0
Xanomeline Low Dose		Week 12	80.0	74.0	6.0
Xanomeline Low Dose		Week 12	90.0	74.0	16.0
Xanomeline Low Dose		Week 16	68.0	72.0	-4.0
Xanomeline Low Dose		Week 16	68.0	74.0	-6.0
Xanomeline Low Dose		Week 16	70.0	74.0	-4.0
Xanomeline Low Dose		Week 2	64.0	72.0	-8.0
Xanomeline Low Dose		Week 2	68.0	74.0	-6.0
Xanomeline Low Dose		Week 2	62.0	74.0	-12.0
Xanomeline Low Dose		Week 20	58.0	72.0	-14.0
Xanomeline Low Dose		Week 20	60.0	74.0	-14.0
Xanomeline Low Dose		Week 20	62.0	74.0	-12.0
Xanomeline Low Dose		Week 24	76.0	72.0	4.0
Xanomeline Low Dose		Week 24	76.0	74.0	2.0
Xanomeline Low Dose		Week 24	74.0	74.0	0.0
Xanomeline Low Dose		Week 26	60.0	72.0	-12.0
Xanomeline Low Dose		Week 26	62.0	74.0	-12.0
Xanomeline Low Dose		Week 26	60.0	74.0	-14.0
Xanomeline Low Dose		Week 4	80.0	72.0	8.0
Xanomeline Low Dose		Week 4	84.0	74.0	10.0
Xanomeline Low Dose		Week 4	84.0	74.0	10.0
Xanomeline Low Dose		Week 6	70.0	72.0	-2.0
Xanomeline Low Dose		Week 6	74.0	74.0	0.0
Xanomeline Low Dose		Week 6	80.0	74.0	6.0
Xanomeline Low Dose		Week 8	70.0	72.0	-2.0
Xanomeline Low Dose		Week 8	72.0	74.0	-2.0
Xanomeline Low Dose		Week 8	70.0	74.0	-4.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			72.0	74.0
Xanomeline Low Dose			70.0	74.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			80.0	74.0
Xanomeline Low Dose			72.0	74.0
Placebo		Week 12	76.0	78.0	-2.0
Placebo		Week 12	84.0	88.0	-4.0
Placebo		Week 12	90.0	76.0	14.0
Placebo		Week 16	80.0	78.0	2.0
Placebo		Week 16	82.0	88.0	-6.0
Placebo		Week 16	82.0	76.0	6.0
Placebo		Week 2	88.0	78.0	10.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	96.0	76.0	20.0
Placebo		Week 20	80.0	78.0	2.0
Placebo		Week 20	90.0	88.0	2.0
Placebo		Week 20	90.0	76.0	14.0
Placebo		Week 24	70.0	78.0	-8.0
Placebo		Week 24	72.0	88.0	-16.0
Placebo		Week 24	72.0	76.0	-4.0
Placebo		Week 26	70.0	78.0	-8.0
Placebo		Week 26	70.0	88.0	-18.0
Placebo		Week 26	70.0	76.0	-6.0
Placebo		Week 4	70.0	78.0	-8.0
Placebo		Week 4	82.0	88.0	-6.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 6	68.0	78.0	-10.0
Placebo		Week 6	76.0	88.0	-12.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 8	74.0	78.0	-4.0
Placebo		Week 8	74.0	88.0	-14.0
Placebo		Week 8	70.0	76.0	-6.0
Placebo			80.0	78.0
Placebo			80.0	88.0
Placebo			86.0	76.0
Placebo			72.0	78.0
Placebo			88.0	88.0
Placebo			90.0	76.0
Xanomeline Low Dose		Week 12	82.0	74.0	8.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 12	82.0	48.0	34.0
Xanomeline Low Dose		Week 2	80.0	74.0	6.0
Xanomeline Low Dose		Week 2	80.0	68.0	12.0
Xanomeline Low Dose		Week 2	80.0	48.0	32.0
Xanomeline Low Dose		Week 4	72.0	74.0	-2.0
Xanomeline Low Dose		Week 4	74.0	68.0	6.0
Xanomeline Low Dose		Week 4	72.0	48.0	24.0
Xanomeline Low Dose		Week 6	80.0	74.0	6.0
Xanomeline Low Dose		Week 6	84.0	68.0	16.0
Xanomeline Low Dose		Week 6	82.0	48.0	34.0
Xanomeline Low Dose		Week 8	82.0	74.0	8.0
Xanomeline Low Dose		Week 8	82.0	68.0	14.0
Xanomeline Low Dose		Week 8	82.0	48.0	34.0
Xanomeline Low Dose			72.0	74.0
Xanomeline Low Dose			74.0	68.0
Xanomeline Low Dose			74.0	48.0
Xanomeline Low Dose			72.0	74.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			72.0	48.0
Xanomeline Low Dose		Week 12	62.0	70.0	-8.0
Xanomeline Low Dose		Week 12	64.0	70.0	-6.0
Xanomeline Low Dose		Week 12	64.0	70.0	-6.0
Xanomeline Low Dose		Week 16	80.0	70.0	10.0
Xanomeline Low Dose		Week 16	82.0	70.0	12.0
Xanomeline Low Dose		Week 16	80.0	70.0	10.0
Xanomeline Low Dose		Week 2	72.0	70.0	2.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 2	72.0	70.0	2.0
Xanomeline Low Dose		Week 20	70.0	70.0	0.0
Xanomeline Low Dose		Week 20	72.0	70.0	2.0
Xanomeline Low Dose		Week 20	68.0	70.0	-2.0
Xanomeline Low Dose		Week 24	62.0	70.0	-8.0
Xanomeline Low Dose		Week 24	74.0	70.0	4.0
Xanomeline Low Dose		Week 24	68.0	70.0	-2.0
Xanomeline Low Dose		Week 4	72.0	70.0	2.0
Xanomeline Low Dose		Week 4	70.0	70.0	0.0
Xanomeline Low Dose		Week 4	68.0	70.0	-2.0
Xanomeline Low Dose		Week 6	70.0	70.0	0.0
Xanomeline Low Dose		Week 6	72.0	70.0	2.0
Xanomeline Low Dose		Week 6	76.0	70.0	6.0
Xanomeline Low Dose		Week 8	70.0	70.0	0.0
Xanomeline Low Dose		Week 8	74.0	70.0	4.0
Xanomeline Low Dose		Week 8	70.0	70.0	0.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			72.0	70.0
Xanomeline Low Dose			44.0	70.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			62.0	70.0
Placebo		Week 12	64.0	72.0	-8.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 16	68.0	72.0	-4.0
Placebo		Week 16	64.0	80.0	-16.0
Placebo		Week 16	62.0	80.0	-18.0
Placebo		Week 2	68.0	72.0	-4.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 20	72.0	72.0	0.0
Placebo		Week 20	68.0	80.0	-12.0
Placebo		Week 20	74.0	80.0	-6.0
Placebo		Week 24	78.0	72.0	6.0
Placebo		Week 24	70.0	80.0	-10.0
Placebo		Week 24	70.0	80.0	-10.0
Placebo		Week 26	70.0	72.0	-2.0
Placebo		Week 26	72.0	80.0	-8.0
Placebo		Week 26	72.0	80.0	-8.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	74.0	80.0	-6.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 6	70.0	72.0	-2.0
Placebo		Week 6	70.0	80.0	-10.0
Placebo		Week 6	70.0	80.0	-10.0
Placebo		Week 8	70.0	72.0	-2.0
Placebo		Week 8	68.0	80.0	-12.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			74.0	72.0
Placebo			82.0	80.0
Placebo			82.0	80.0
Placebo			58.0	72.0
Placebo			64.0	80.0
Placebo			62.0	80.0
Xanomeline Low Dose		Week 12	68.0	78.0	-10.0
Xanomeline Low Dose		Week 12	64.0	78.0	-14.0
Xanomeline Low Dose		Week 12	80.0	76.0	4.0
Xanomeline Low Dose		Week 16	62.0	78.0	-16.0
Xanomeline Low Dose		Week 16	72.0	78.0	-6.0
Xanomeline Low Dose		Week 16	72.0	76.0	-4.0
Xanomeline Low Dose		Week 2	74.0	78.0	-4.0
Xanomeline Low Dose		Week 2	80.0	78.0	2.0
Xanomeline Low Dose		Week 2	82.0	76.0	6.0
Xanomeline Low Dose		Week 20	80.0	78.0	2.0
Xanomeline Low Dose		Week 20	80.0	78.0	2.0
Xanomeline Low Dose		Week 20	84.0	76.0	8.0
Xanomeline Low Dose		Week 24	76.0	78.0	-2.0
Xanomeline Low Dose		Week 24	80.0	78.0	2.0
Xanomeline Low Dose		Week 24	78.0	76.0	2.0
Xanomeline Low Dose		Week 4	76.0	78.0	-2.0
Xanomeline Low Dose		Week 4	80.0	78.0	2.0
Xanomeline Low Dose		Week 4	80.0	76.0	4.0
Xanomeline Low Dose		Week 6	70.0	78.0	-8.0
Xanomeline Low Dose		Week 6	70.0	78.0	-8.0
Xanomeline Low Dose		Week 6	70.0	76.0	-6.0
Xanomeline Low Dose		Week 8	74.0	78.0	-4.0
Xanomeline Low Dose		Week 8	78.0	78.0	0.0
Xanomeline Low Dose		Week 8	74.0	76.0	-2.0
Xanomeline Low Dose			72.0	78.0
Xanomeline Low Dose			80.0	78.0
Xanomeline Low Dose			82.0	76.0
Xanomeline Low Dose			68.0	78.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			70.0	76.0
Placebo		Week 12	68.0	62.0	6.0
Placebo		Week 12	70.0	68.0	2.0
Placebo		Week 12	80.0	74.0	6.0
Placebo		Week 16	70.0	62.0	8.0
Placebo		Week 16	68.0	68.0	0.0
Placebo		Week 16	76.0	74.0	2.0
Placebo		Week 2	70.0	62.0	8.0
Placebo		Week 2	74.0	68.0	6.0
Placebo		Week 2	80.0	74.0	6.0
Placebo		Week 20	64.0	62.0	2.0
Placebo		Week 20	66.0	68.0	-2.0
Placebo		Week 20	78.0	74.0	4.0
Placebo		Week 24	70.0	62.0	8.0
Placebo		Week 24	80.0	68.0	12.0
Placebo		Week 24	80.0	74.0	6.0
Placebo		Week 26	70.0	62.0	8.0
Placebo		Week 26	70.0	68.0	2.0
Placebo		Week 26	80.0	74.0	6.0
Placebo		Week 4	60.0	62.0	-2.0
Placebo		Week 4	70.0	68.0	2.0
Placebo		Week 4	70.0	74.0	-4.0
Placebo		Week 6	58.0	62.0	-4.0
Placebo		Week 6	70.0	68.0	2.0
Placebo		Week 6	70.0	74.0	-4.0
Placebo		Week 8	72.0	62.0	10.0
Placebo		Week 8	72.0	68.0	4.0
Placebo		Week 8	70.0	74.0	-4.0
Xanomeline High Dose		Week 12	70.0	72.0	-2.0
Xanomeline High Dose		Week 12	72.0	72.0	0.0
Xanomeline High Dose		Week 12	70.0	72.0	-2.0
Xanomeline High Dose		Week 16	70.0	72.0	-2.0
Xanomeline High Dose		Week 16	68.0	72.0	-4.0
Xanomeline High Dose		Week 16	62.0	72.0	-10.0
Xanomeline High Dose		Week 2	60.0	72.0	-12.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 4	64.0	72.0	-8.0
Xanomeline High Dose		Week 4	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	68.0	72.0	-4.0
Xanomeline High Dose		Week 6	70.0	72.0	-2.0
Xanomeline High Dose		Week 6	68.0	72.0	-4.0
Xanomeline High Dose		Week 6	72.0	72.0	0.0
Xanomeline High Dose		Week 8	68.0	72.0	-4.0
Xanomeline High Dose		Week 8	70.0	72.0	-2.0
Xanomeline High Dose		Week 8	70.0	72.0	-2.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			66.0	72.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			66.0	72.0
Xanomeline High Dose			68.0	72.0
Xanomeline High Dose		Week 2	82.0	76.0	6.0
Xanomeline High Dose		Week 2	80.0	70.0	10.0
Xanomeline High Dose		Week 2	90.0	74.0	16.0
Xanomeline High Dose		Week 4	82.0	76.0	6.0
Xanomeline High Dose		Week 4	90.0	70.0	20.0
Xanomeline High Dose		Week 4	82.0	74.0	8.0
Xanomeline High Dose			78.0	76.0
Xanomeline High Dose			74.0	70.0
Xanomeline High Dose			72.0	74.0
Xanomeline High Dose			72.0	76.0
Xanomeline High Dose			82.0	70.0
Xanomeline High Dose			80.0	74.0
Xanomeline Low Dose		Week 2	72.0	82.0	-10.0
Xanomeline Low Dose		Week 2	72.0	80.0	-8.0
Xanomeline Low Dose		Week 2	72.0	82.0	-10.0
Xanomeline Low Dose		Week 4	74.0	82.0	-8.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	80.0	82.0	-2.0
Xanomeline Low Dose		Week 6	60.0	82.0	-22.0
Xanomeline Low Dose		Week 6	70.0	80.0	-10.0
Xanomeline Low Dose		Week 6	70.0	82.0	-12.0
Xanomeline Low Dose		Week 8	80.0	82.0	-2.0
Xanomeline Low Dose		Week 8	90.0	80.0	10.0
Xanomeline Low Dose		Week 8	88.0	82.0	6.0
Placebo		Week 2	78.0	88.0	-10.0
Placebo		Week 2	74.0	88.0	-14.0
Placebo		Week 2	72.0	84.0	-12.0
Placebo		Week 4	70.0	88.0	-18.0
Placebo		Week 4	70.0	88.0	-18.0
Placebo		Week 4	70.0	84.0	-14.0
Placebo		Week 6	70.0	88.0	-18.0
Placebo		Week 6	80.0	88.0	-8.0
Placebo		Week 6	72.0	84.0	-12.0
Placebo			74.0	88.0
Placebo			74.0	88.0
Placebo			74.0	84.0
Placebo			70.0	88.0
Placebo			72.0	88.0
Placebo			76.0	84.0
Xanomeline Low Dose		Week 12	58.0	72.0	-14.0
Xanomeline Low Dose		Week 12	60.0	78.0	-18.0
Xanomeline Low Dose		Week 12	66.0	74.0	-8.0
Xanomeline Low Dose		Week 16	70.0	72.0	-2.0
Xanomeline Low Dose		Week 16	90.0	78.0	12.0
Xanomeline Low Dose		Week 16	70.0	74.0	-4.0
Xanomeline Low Dose		Week 2	78.0	72.0	6.0
Xanomeline Low Dose		Week 2	80.0	78.0	2.0
Xanomeline Low Dose		Week 2	78.0	74.0	4.0
Xanomeline Low Dose		Week 4	66.0	72.0	-6.0
Xanomeline Low Dose		Week 4	80.0	78.0	2.0
Xanomeline Low Dose		Week 4	78.0	74.0	4.0
Xanomeline Low Dose		Week 6	70.0	72.0	-2.0
Xanomeline Low Dose		Week 6	70.0	78.0	-8.0
Xanomeline Low Dose		Week 6	70.0	74.0	-4.0
Xanomeline Low Dose		Week 8	80.0	72.0	8.0
Xanomeline Low Dose		Week 8	80.0	78.0	2.0
Xanomeline Low Dose		Week 8	80.0	74.0	6.0
Xanomeline High Dose		Week 12	60.0	96.0	-36.0
Xanomeline High Dose		Week 12	62.0	108.0	-46.0
Xanomeline High Dose		Week 12	62.0	102.0	-40.0
Xanomeline High Dose		Week 16	60.0	96.0	-36.0
Xanomeline High Dose		Week 16	70.0	108.0	-38.0
Xanomeline High Dose		Week 16	70.0	102.0	-32.0
Xanomeline High Dose		Week 2	80.0	96.0	-16.0
Xanomeline High Dose		Week 2	82.0	108.0	-26.0
Xanomeline High Dose		Week 2	82.0	102.0	-20.0
Xanomeline High Dose		Week 20	60.0	96.0	-36.0
Xanomeline High Dose		Week 20	72.0	108.0	-36.0
Xanomeline High Dose		Week 20	80.0	102.0	-22.0
Xanomeline High Dose		Week 24	90.0	96.0	-6.0
Xanomeline High Dose		Week 24	90.0	108.0	-18.0
Xanomeline High Dose		Week 24	88.0	102.0	-14.0
Xanomeline High Dose		Week 26	80.0	96.0	-16.0
Xanomeline High Dose		Week 26	88.0	108.0	-20.0
Xanomeline High Dose		Week 26	88.0	102.0	-14.0
Xanomeline High Dose		Week 4	70.0	96.0	-26.0
Xanomeline High Dose		Week 4	78.0	108.0	-30.0
Xanomeline High Dose		Week 4	76.0	102.0	-26.0
Xanomeline High Dose		Week 6	70.0	96.0	-26.0
Xanomeline High Dose		Week 6	84.0	108.0	-24.0
Xanomeline High Dose		Week 6	84.0	102.0	-18.0
Xanomeline High Dose		Week 8	80.0	96.0	-16.0
Xanomeline High Dose		Week 8	88.0	108.0	-20.0
Xanomeline High Dose		Week 8	90.0	102.0	-12.0
Xanomeline High Dose		Week 2	68.0	68.0	0.0
Xanomeline High Dose		Week 2	70.0	70.0	0.0
Xanomeline High Dose		Week 2	74.0	68.0	6.0
Xanomeline High Dose		Week 4	62.0	68.0	-6.0
Xanomeline High Dose		Week 4	60.0	70.0	-10.0
Xanomeline High Dose		Week 4	68.0	68.0	0.0
Xanomeline High Dose		Week 6	62.0	68.0	-6.0
Xanomeline High Dose		Week 6	62.0	70.0	-8.0
Xanomeline High Dose		Week 6	60.0	68.0	-8.0
Xanomeline High Dose		Week 8	70.0	68.0	2.0
Xanomeline High Dose		Week 8	74.0	70.0	4.0
Xanomeline High Dose		Week 8	80.0	68.0	12.0
Xanomeline High Dose			62.0	68.0
Xanomeline High Dose			68.0	70.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	82.0	74.0	8.0
Xanomeline High Dose		Week 12	84.0	80.0	4.0
Xanomeline High Dose		Week 16	72.0	80.0	-8.0
Xanomeline High Dose		Week 16	72.0	74.0	-2.0
Xanomeline High Dose		Week 16	72.0	80.0	-8.0
Xanomeline High Dose		Week 2	80.0	80.0	0.0
Xanomeline High Dose		Week 2	90.0	74.0	16.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 20	54.0	80.0	-26.0
Xanomeline High Dose		Week 20	58.0	74.0	-16.0
Xanomeline High Dose		Week 20	60.0	80.0	-20.0
Xanomeline High Dose		Week 24	74.0	80.0	-6.0
Xanomeline High Dose		Week 24	72.0	74.0	-2.0
Xanomeline High Dose		Week 24	72.0	80.0	-8.0
Xanomeline High Dose		Week 26	80.0	80.0	0.0
Xanomeline High Dose		Week 26	78.0	74.0	4.0
Xanomeline High Dose		Week 26	70.0	80.0	-10.0
Xanomeline High Dose		Week 4	78.0	80.0	-2.0
Xanomeline High Dose		Week 4	76.0	74.0	2.0
Xanomeline High Dose		Week 4	82.0	80.0	2.0
Xanomeline High Dose		Week 6	70.0	80.0	-10.0
Xanomeline High Dose		Week 6	70.0	74.0	-4.0
Xanomeline High Dose		Week 6	72.0	80.0	-8.0
Xanomeline High Dose		Week 8	84.0	80.0	4.0
Xanomeline High Dose		Week 8	80.0	74.0	6.0
Xanomeline High Dose		Week 8	82.0	80.0	2.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	74.0
Xanomeline High Dose			80.0	80.0
Placebo		Week 12	60.0	68.0	-8.0
Placebo		Week 12	60.0	70.0	-10.0
Placebo		Week 12	58.0	66.0	-8.0
Placebo		Week 16	60.0	68.0	-8.0
Placebo		Week 16	60.0	70.0	-10.0
Placebo		Week 16	66.0	66.0	0.0
Placebo		Week 2	68.0	68.0	0.0
Placebo		Week 2	60.0	70.0	-10.0
Placebo		Week 2	68.0	66.0	2.0
Placebo		Week 20	70.0	68.0	2.0
Placebo		Week 20	62.0	70.0	-8.0
Placebo		Week 20	70.0	66.0	4.0
Placebo		Week 24	60.0	68.0	-8.0
Placebo		Week 24	60.0	70.0	-10.0
Placebo		Week 24	62.0	66.0	-4.0
Placebo		Week 26	62.0	68.0	-6.0
Placebo		Week 26	62.0	70.0	-8.0
Placebo		Week 26	62.0	66.0	-4.0
Placebo		Week 4	72.0	68.0	4.0
Placebo		Week 4	64.0	70.0	-6.0
Placebo		Week 4	72.0	66.0	6.0
Placebo		Week 6	80.0	68.0	12.0
Placebo		Week 6	82.0	70.0	12.0
Placebo		Week 6	80.0	66.0	14.0
Placebo		Week 8	78.0	68.0	10.0
Placebo		Week 8	80.0	70.0	10.0
Placebo		Week 8	80.0	66.0	14.0
Placebo			74.0	68.0
Placebo			66.0	70.0
Placebo			70.0	66.0
Placebo			80.0	68.0
Placebo			72.0	70.0
Placebo			70.0	66.0
Xanomeline High Dose		Week 12	74.0	68.0	6.0
Xanomeline High Dose		Week 12	62.0	66.0	-4.0
Xanomeline High Dose		Week 12	68.0	70.0	-2.0
Xanomeline High Dose		Week 16	70.0	68.0	2.0
Xanomeline High Dose		Week 16	72.0	66.0	6.0
Xanomeline High Dose		Week 16	78.0	70.0	8.0
Xanomeline High Dose		Week 2	60.0	68.0	-8.0
Xanomeline High Dose		Week 2	64.0	66.0	-2.0
Xanomeline High Dose		Week 2	62.0	70.0	-8.0
Xanomeline High Dose		Week 20	64.0	68.0	-4.0
Xanomeline High Dose		Week 20	60.0	66.0	-6.0
Xanomeline High Dose		Week 20	62.0	70.0	-8.0
Xanomeline High Dose		Week 24	62.0	68.0	-6.0
Xanomeline High Dose		Week 24	64.0	66.0	-2.0
Xanomeline High Dose		Week 24	70.0	70.0	0.0
Xanomeline High Dose		Week 26	70.0	68.0	2.0
Xanomeline High Dose		Week 26	72.0	66.0	6.0
Xanomeline High Dose		Week 26	70.0	70.0	0.0
Xanomeline High Dose		Week 4	90.0	68.0	22.0
Xanomeline High Dose		Week 4	92.0	66.0	26.0
Xanomeline High Dose		Week 4	88.0	70.0	18.0
Xanomeline High Dose		Week 6	60.0	68.0	-8.0
Xanomeline High Dose		Week 6	62.0	66.0	-4.0
Xanomeline High Dose		Week 6	62.0	70.0	-8.0
Xanomeline High Dose		Week 8	70.0	68.0	2.0
Xanomeline High Dose		Week 8	72.0	66.0	6.0
Xanomeline High Dose		Week 8	72.0	70.0	2.0
Xanomeline High Dose			72.0	68.0
Xanomeline High Dose			70.0	66.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			68.0	66.0
Xanomeline High Dose			70.0	70.0
Xanomeline Low Dose		Week 12	70.0	64.0	6.0
Xanomeline Low Dose		Week 12	68.0	72.0	-4.0
Xanomeline Low Dose		Week 12	70.0	74.0	-4.0
Xanomeline Low Dose		Week 16	80.0	64.0	16.0
Xanomeline Low Dose		Week 16	74.0	72.0	2.0
Xanomeline Low Dose		Week 16	74.0	74.0	0.0
Xanomeline Low Dose		Week 2	76.0	64.0	12.0
Xanomeline Low Dose		Week 2	78.0	72.0	6.0
Xanomeline Low Dose		Week 2	76.0	74.0	2.0
Xanomeline Low Dose		Week 20	72.0	64.0	8.0
Xanomeline Low Dose		Week 20	78.0	72.0	6.0
Xanomeline Low Dose		Week 20	78.0	74.0	4.0
Xanomeline Low Dose		Week 24	80.0	64.0	16.0
Xanomeline Low Dose		Week 24	72.0	72.0	0.0
Xanomeline Low Dose		Week 24	70.0	74.0	-4.0
Xanomeline Low Dose		Week 26	68.0	64.0	4.0
Xanomeline Low Dose		Week 26	72.0	72.0	0.0
Xanomeline Low Dose		Week 26	78.0	74.0	4.0
Xanomeline Low Dose		Week 4	68.0	64.0	4.0
Xanomeline Low Dose		Week 4	74.0	72.0	2.0
Xanomeline Low Dose		Week 4	66.0	74.0	-8.0
Xanomeline Low Dose		Week 6	78.0	64.0	14.0
Xanomeline Low Dose		Week 6	64.0	72.0	-8.0
Xanomeline Low Dose		Week 6	68.0	74.0	-6.0
Xanomeline Low Dose		Week 8	72.0	64.0	8.0
Xanomeline Low Dose		Week 8	76.0	72.0	4.0
Xanomeline Low Dose		Week 8	72.0	74.0	-2.0
Xanomeline Low Dose			80.0	64.0
Xanomeline Low Dose			80.0	72.0
Xanomeline Low Dose			78.0	74.0
Xanomeline Low Dose			72.0	64.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			64.0	74.0
Xanomeline High Dose		Week 12	80.0	82.0	-2.0
Xanomeline High Dose		Week 12	82.0	80.0	2.0
Xanomeline High Dose		Week 12	79.0	78.0	1.0
Xanomeline High Dose		Week 16	82.0	82.0	0.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 16	70.0	78.0	-8.0
Xanomeline High Dose		Week 2	74.0	82.0	-8.0
Xanomeline High Dose		Week 2	60.0	80.0	-20.0
Xanomeline High Dose		Week 2	58.0	78.0	-20.0
Xanomeline High Dose		Week 20	78.0	82.0	-4.0
Xanomeline High Dose		Week 20	62.0	80.0	-18.0
Xanomeline High Dose		Week 20	60.0	78.0	-18.0
Xanomeline High Dose		Week 24	74.0	82.0	-8.0
Xanomeline High Dose		Week 24	70.0	80.0	-10.0
Xanomeline High Dose		Week 24	68.0	78.0	-10.0
Xanomeline High Dose		Week 26	70.0	82.0	-12.0
Xanomeline High Dose		Week 26	68.0	80.0	-12.0
Xanomeline High Dose		Week 26	72.0	78.0	-6.0
Xanomeline High Dose		Week 4	70.0	82.0	-12.0
Xanomeline High Dose		Week 4	68.0	80.0	-12.0
Xanomeline High Dose		Week 4	66.0	78.0	-12.0
Xanomeline High Dose		Week 6	70.0	82.0	-12.0
Xanomeline High Dose		Week 6	62.0	80.0	-18.0
Xanomeline High Dose		Week 6	62.0	78.0	-16.0
Xanomeline High Dose		Week 8	82.0	82.0	0.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose		Week 8	78.0	78.0	0.0
Xanomeline High Dose			66.0	82.0
Xanomeline High Dose			54.0	80.0
Xanomeline High Dose			68.0	78.0
Xanomeline High Dose			74.0	82.0
Xanomeline High Dose			72.0	80.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose		Week 12	62.0	72.0	-10.0
Xanomeline High Dose		Week 12	64.0	74.0	-10.0
Xanomeline High Dose		Week 12	62.0	72.0	-10.0
Xanomeline High Dose		Week 16	72.0	72.0	0.0
Xanomeline High Dose		Week 16	70.0	74.0	-4.0
Xanomeline High Dose		Week 16	68.0	72.0	-4.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	70.0	74.0	-4.0
Xanomeline High Dose		Week 2	68.0	72.0	-4.0
Xanomeline High Dose		Week 20	72.0	72.0	0.0
Xanomeline High Dose		Week 20	66.0	74.0	-8.0
Xanomeline High Dose		Week 20	72.0	72.0	0.0
Xanomeline High Dose		Week 24	64.0	72.0	-8.0
Xanomeline High Dose		Week 24	62.0	74.0	-12.0
Xanomeline High Dose		Week 24	70.0	72.0	-2.0
Xanomeline High Dose		Week 26	70.0	72.0	-2.0
Xanomeline High Dose		Week 26	72.0	74.0	-2.0
Xanomeline High Dose		Week 26	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	74.0	72.0	2.0
Xanomeline High Dose		Week 4	70.0	74.0	-4.0
Xanomeline High Dose		Week 4	70.0	72.0	-2.0
Xanomeline High Dose		Week 6	80.0	72.0	8.0
Xanomeline High Dose		Week 6	84.0	74.0	10.0
Xanomeline High Dose		Week 6	82.0	72.0	10.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 8	82.0	74.0	8.0
Xanomeline High Dose		Week 8	78.0	72.0	6.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			70.0	74.0
Xanomeline High Dose			68.0	72.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 2	70.0	78.0	-8.0
Placebo		Week 2	66.0	76.0	-10.0
Placebo		Week 4	78.0	80.0	-2.0
Placebo		Week 4	74.0	78.0	-4.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 6	78.0	80.0	-2.0
Placebo		Week 6	76.0	78.0	-2.0
Placebo		Week 6	76.0	76.0	0.0
Placebo		Week 8	84.0	80.0	4.0
Placebo		Week 8	80.0	78.0	2.0
Placebo		Week 8	84.0	76.0	8.0
Placebo			88.0	80.0
Placebo			86.0	78.0
Placebo			80.0	76.0
Placebo			72.0	80.0
Placebo			70.0	78.0
Placebo			70.0	76.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	82.0	86.0	-4.0
Placebo		Week 2	80.0	86.0	-6.0
Placebo		Week 4	88.0	88.0	0.0
Placebo		Week 4	94.0	86.0	8.0
Placebo		Week 4	96.0	86.0	10.0
Placebo		Week 6	76.0	88.0	-12.0
Placebo		Week 6	80.0	86.0	-6.0
Placebo		Week 6	78.0	86.0	-8.0
Placebo		Week 8	78.0	88.0	-10.0
Placebo		Week 8	84.0	86.0	-2.0
Placebo		Week 8	86.0	86.0	0.0
Placebo			94.0	88.0
Placebo			92.0	86.0
Placebo			90.0	86.0
Placebo			84.0	88.0
Placebo			92.0	86.0
Placebo			88.0	86.0
Xanomeline High Dose		Week 12	64.0	70.0	-6.0
Xanomeline High Dose		Week 12	60.0	64.0	-4.0
Xanomeline High Dose		Week 12	70.0	68.0	2.0
Xanomeline High Dose		Week 16	72.0	70.0	2.0
Xanomeline High Dose		Week 16	70.0	64.0	6.0
Xanomeline High Dose		Week 16	70.0	68.0	2.0
Xanomeline High Dose		Week 2	70.0	70.0	0.0
Xanomeline High Dose		Week 2	72.0	64.0	8.0
Xanomeline High Dose		Week 2	74.0	68.0	6.0
Xanomeline High Dose		Week 20	70.0	70.0	0.0
Xanomeline High Dose		Week 20	68.0	64.0	4.0
Xanomeline High Dose		Week 20	81.0	68.0	13.0
Xanomeline High Dose		Week 4	80.0	70.0	10.0
Xanomeline High Dose		Week 4	78.0	64.0	14.0
Xanomeline High Dose		Week 4	80.0	68.0	12.0
Xanomeline High Dose		Week 6	60.0	70.0	-10.0
Xanomeline High Dose		Week 6	62.0	64.0	-2.0
Xanomeline High Dose		Week 6	70.0	68.0	2.0
Xanomeline High Dose		Week 8	72.0	70.0	2.0
Xanomeline High Dose		Week 8	78.0	64.0	14.0
Xanomeline High Dose		Week 8	78.0	68.0	10.0
Xanomeline Low Dose		Week 12	80.0	76.0	4.0
Xanomeline Low Dose		Week 12	80.0	72.0	8.0
Xanomeline Low Dose		Week 12	88.0	70.0	18.0
Xanomeline Low Dose		Week 16	76.0	76.0	0.0
Xanomeline Low Dose		Week 16	86.0	72.0	14.0
Xanomeline Low Dose		Week 16	84.0	70.0	14.0
Xanomeline Low Dose		Week 2	88.0	76.0	12.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 20	64.0	76.0	-12.0
Xanomeline Low Dose		Week 20	60.0	72.0	-12.0
Xanomeline Low Dose		Week 20	60.0	70.0	-10.0
Xanomeline Low Dose		Week 24	70.0	76.0	-6.0
Xanomeline Low Dose		Week 24	78.0	72.0	6.0
Xanomeline Low Dose		Week 24	76.0	70.0	6.0
Xanomeline Low Dose		Week 4	72.0	76.0	-4.0
Xanomeline Low Dose		Week 4	70.0	72.0	-2.0
Xanomeline Low Dose		Week 4	68.0	70.0	-2.0
Xanomeline Low Dose		Week 6	80.0	76.0	4.0
Xanomeline Low Dose		Week 6	78.0	72.0	6.0
Xanomeline Low Dose		Week 6	78.0	70.0	8.0
Xanomeline Low Dose		Week 8	84.0	76.0	8.0
Xanomeline Low Dose		Week 8	88.0	72.0	16.0
Xanomeline Low Dose		Week 8	86.0	70.0	16.0
Xanomeline Low Dose			88.0	76.0
Xanomeline Low Dose			86.0	72.0
Xanomeline Low Dose			86.0	70.0
Xanomeline Low Dose			70.0	76.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			68.0	70.0
Xanomeline Low Dose		Week 2	57.0	72.0	-15.0
Xanomeline Low Dose		Week 2	64.0	69.0	-5.0
Xanomeline Low Dose		Week 2	66.0	69.0	-3.0
Xanomeline Low Dose		Week 4	57.0	72.0	-15.0
Xanomeline Low Dose		Week 4	65.0	69.0	-4.0
Xanomeline Low Dose		Week 4	69.0	69.0	0.0
Xanomeline Low Dose			76.0	72.0
Xanomeline Low Dose			74.0	69.0
Xanomeline Low Dose			82.0	69.0
Xanomeline Low Dose			64.0	72.0
Xanomeline Low Dose			69.0	69.0
Xanomeline Low Dose			75.0	69.0
Xanomeline High Dose		Week 12	68.0	71.0	-3.0
Xanomeline High Dose		Week 12	71.0	77.0	-6.0
Xanomeline High Dose		Week 12	73.0	75.0	-2.0
Xanomeline High Dose		Week 16	69.0	71.0	-2.0
Xanomeline High Dose		Week 16	72.0	77.0	-5.0
Xanomeline High Dose		Week 16	72.0	75.0	-3.0
Xanomeline High Dose		Week 2	78.0	71.0	7.0
Xanomeline High Dose		Week 2	69.0	77.0	-8.0
Xanomeline High Dose		Week 2	80.0	75.0	5.0
Xanomeline High Dose		Week 20	69.0	71.0	-2.0
Xanomeline High Dose		Week 20	76.0	77.0	-1.0
Xanomeline High Dose		Week 20	68.0	75.0	-7.0
Xanomeline High Dose		Week 4	71.0	71.0	0.0
Xanomeline High Dose		Week 4	76.0	77.0	-1.0
Xanomeline High Dose		Week 4	68.0	75.0	-7.0
Xanomeline High Dose		Week 6	68.0	71.0	-3.0
Xanomeline High Dose		Week 6	72.0	77.0	-5.0
Xanomeline High Dose		Week 6	76.0	75.0	1.0
Xanomeline High Dose		Week 8	60.0	71.0	-11.0
Xanomeline High Dose		Week 8	73.0	77.0	-4.0
Xanomeline High Dose		Week 8	74.0	75.0	-1.0
Xanomeline High Dose			65.0	71.0
Xanomeline High Dose			73.0	77.0
Xanomeline High Dose			68.0	75.0
Xanomeline High Dose			57.0	71.0
Xanomeline High Dose			69.0	77.0
Xanomeline High Dose			68.0	75.0
Placebo		Week 12	73.0	82.0	-9.0
Placebo		Week 12	79.0	87.0	-8.0
Placebo		Week 12	83.0	87.0	-4.0
Placebo		Week 16	71.0	82.0	-11.0
Placebo		Week 16	86.0	87.0	-1.0
Placebo		Week 16	75.0	87.0	-12.0
Placebo		Week 2	84.0	82.0	2.0
Placebo		Week 2	84.0	87.0	-3.0
Placebo		Week 2	84.0	87.0	-3.0
Placebo		Week 20	78.0	82.0	-4.0
Placebo		Week 20	78.0	87.0	-9.0
Placebo		Week 20	78.0	87.0	-9.0
Placebo		Week 24	83.0	82.0	1.0
Placebo		Week 24	79.0	87.0	-8.0
Placebo		Week 24	74.0	87.0	-13.0
Placebo		Week 26	71.0	82.0	-11.0
Placebo		Week 26	68.0	87.0	-19.0
Placebo		Week 26	73.0	87.0	-14.0
Placebo		Week 4	70.0	82.0	-12.0
Placebo		Week 4	78.0	87.0	-9.0
Placebo		Week 4	74.0	87.0	-13.0
Placebo		Week 6	64.0	82.0	-18.0
Placebo		Week 6	84.0	87.0	-3.0
Placebo		Week 6	76.0	87.0	-11.0
Placebo		Week 8	73.0	82.0	-9.0
Placebo		Week 8	88.0	87.0	1.0
Placebo		Week 8	81.0	87.0	-6.0
Placebo			86.0	82.0
Placebo			86.0	87.0
Placebo			89.0	87.0
Placebo			63.0	82.0
Placebo			74.0	87.0
Placebo			80.0	87.0
Placebo		Week 12	68.0	73.0	-5.0
Placebo		Week 12	75.0	87.0	-12.0
Placebo		Week 12	67.0	77.0	-10.0
Placebo		Week 16	64.0	73.0	-9.0
Placebo		Week 16	59.0	87.0	-28.0
Placebo		Week 16	60.0	77.0	-17.0
Placebo		Week 2	65.0	73.0	-8.0
Placebo		Week 2	80.0	87.0	-7.0
Placebo		Week 2	58.0	77.0	-19.0
Placebo		Week 20	64.0	73.0	-9.0
Placebo		Week 20	73.0	87.0	-14.0
Placebo		Week 20	65.0	77.0	-12.0
Placebo		Week 24	57.0	73.0	-16.0
Placebo		Week 24	59.0	87.0	-28.0
Placebo		Week 24	67.0	77.0	-10.0
Placebo		Week 4	72.0	73.0	-1.0
Placebo		Week 4	68.0	87.0	-19.0
Placebo		Week 4	71.0	77.0	-6.0
Placebo		Week 6	64.0	73.0	-9.0
Placebo		Week 6	69.0	87.0	-18.0
Placebo		Week 6	61.0	77.0	-16.0
Placebo		Week 8	78.0	73.0	5.0
Placebo		Week 8	70.0	87.0	-17.0
Placebo		Week 8	72.0	77.0	-5.0
Placebo			84.0	73.0
Placebo			84.0	87.0
Placebo			80.0	77.0
Placebo			82.0	73.0
Placebo			82.0	87.0
Placebo			90.0	77.0
Xanomeline Low Dose		Week 2	92.0	82.0	10.0
Xanomeline Low Dose		Week 2	90.0	76.0	14.0
Xanomeline Low Dose		Week 2	88.0	73.0	15.0
Xanomeline Low Dose			90.0	82.0
Xanomeline Low Dose			88.0	76.0
Xanomeline Low Dose			90.0	73.0
Placebo		Week 12	99.0	99.0	0.0
Placebo		Week 12	92.0	91.0	1.0
Placebo		Week 12	100.0	95.0	5.0
Placebo		Week 2	90.0	99.0	-9.0
Placebo		Week 2	94.0	91.0	3.0
Placebo		Week 2	90.0	95.0	-5.0
Placebo		Week 4	87.0	99.0	-12.0
Placebo		Week 4	95.0	91.0	4.0
Placebo		Week 4	91.0	95.0	-4.0
Placebo		Week 6	84.0	99.0	-15.0
Placebo		Week 6	80.0	91.0	-11.0
Placebo		Week 6	80.0	95.0	-15.0
Placebo		Week 8	85.0	99.0	-14.0
Placebo		Week 8	83.0	91.0	-8.0
Placebo		Week 8	92.0	95.0	-3.0
Placebo			90.0	99.0
Placebo			86.0	91.0
Placebo			89.0	95.0
Placebo			77.0	99.0
Placebo			84.0	91.0
Placebo			85.0	95.0
Xanomeline Low Dose		Week 12	63.0	59.0	4.0
Xanomeline Low Dose		Week 12	55.0	63.0	-8.0
Xanomeline Low Dose		Week 12	66.0	62.0	4.0
Xanomeline Low Dose		Week 16	56.0	59.0	-3.0
Xanomeline Low Dose		Week 16	55.0	63.0	-8.0
Xanomeline Low Dose		Week 16	56.0	62.0	-6.0
Xanomeline Low Dose		Week 2	64.0	59.0	5.0
Xanomeline Low Dose		Week 2	64.0	63.0	1.0
Xanomeline Low Dose		Week 2	61.0	62.0	-1.0
Xanomeline Low Dose		Week 4	59.0	59.0	0.0
Xanomeline Low Dose		Week 4	56.0	63.0	-7.0
Xanomeline Low Dose		Week 4	56.0	62.0	-6.0
Xanomeline Low Dose		Week 6	60.0	59.0	1.0
Xanomeline Low Dose		Week 6	60.0	63.0	-3.0
Xanomeline Low Dose		Week 6	52.0	62.0	-10.0
Xanomeline Low Dose		Week 8	64.0	59.0	5.0
Xanomeline Low Dose		Week 8	62.0	63.0	-1.0
Xanomeline Low Dose		Week 8	62.0	62.0	0.0
Xanomeline Low Dose			70.0	59.0
Xanomeline Low Dose			70.0	63.0
Xanomeline Low Dose			68.0	62.0
Xanomeline Low Dose			56.0	59.0
Xanomeline Low Dose			53.0	63.0
Xanomeline Low Dose			56.0	62.0
Xanomeline Low Dose		Week 12	70.0	87.0	-17.0
Xanomeline Low Dose		Week 12	75.0	68.0	7.0
Xanomeline Low Dose		Week 12	71.0	58.0	13.0
Xanomeline Low Dose		Week 16	64.0	87.0	-23.0
Xanomeline Low Dose		Week 16	59.0	68.0	-9.0
Xanomeline Low Dose		Week 16	61.0	58.0	3.0
Xanomeline Low Dose		Week 2	64.0	87.0	-23.0
Xanomeline Low Dose		Week 2	66.0	68.0	-2.0
Xanomeline Low Dose		Week 2	68.0	58.0	10.0
Xanomeline Low Dose		Week 20	77.0	87.0	-10.0
Xanomeline Low Dose		Week 20	71.0	68.0	3.0
Xanomeline Low Dose		Week 20	76.0	58.0	18.0
Xanomeline Low Dose		Week 24	79.0	87.0	-8.0
Xanomeline Low Dose		Week 24	69.0	68.0	1.0
Xanomeline Low Dose		Week 24	64.0	58.0	6.0
Xanomeline Low Dose		Week 26	72.0	87.0	-15.0
Xanomeline Low Dose		Week 26	69.0	68.0	1.0
Xanomeline Low Dose		Week 26	80.0	58.0	22.0
Xanomeline Low Dose		Week 4	73.0	87.0	-14.0
Xanomeline Low Dose		Week 4	55.0	68.0	-13.0
Xanomeline Low Dose		Week 4	66.0	58.0	8.0
Xanomeline Low Dose		Week 6	58.0	87.0	-29.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	65.0	58.0	7.0
Xanomeline Low Dose		Week 8	64.0	87.0	-23.0
Xanomeline Low Dose		Week 8	54.0	68.0	-14.0
Xanomeline Low Dose		Week 8	64.0	58.0	6.0
Xanomeline Low Dose			74.0	87.0
Xanomeline Low Dose			64.0	68.0
Xanomeline Low Dose			66.0	58.0
Xanomeline Low Dose			68.0	87.0
Xanomeline Low Dose			61.0	68.0
Xanomeline Low Dose			57.0	58.0
Xanomeline High Dose		Week 2	76.0	69.0	7.0
Xanomeline High Dose		Week 2	66.0	61.0	5.0
Xanomeline High Dose		Week 2	60.0	73.0	-13.0
Xanomeline High Dose		Week 4	65.0	69.0	-4.0
Xanomeline High Dose		Week 4	56.0	61.0	-5.0
Xanomeline High Dose		Week 4	61.0	73.0	-12.0
Xanomeline High Dose		Week 6	74.0	69.0	5.0
Xanomeline High Dose		Week 6	68.0	61.0	7.0
Xanomeline High Dose		Week 6	66.0	73.0	-7.0
Xanomeline High Dose		Week 8	64.0	69.0	-5.0
Xanomeline High Dose		Week 8	80.0	61.0	19.0
Xanomeline High Dose		Week 8	57.0	73.0	-16.0
Xanomeline High Dose			65.0	69.0
Xanomeline High Dose			73.0	61.0
Xanomeline High Dose			73.0	73.0
Placebo		Week 12	85.0	68.0	17.0
Placebo		Week 12	72.0	93.0	-21.0
Placebo		Week 12	84.0	77.0	7.0
Placebo		Week 16	83.0	68.0	15.0
Placebo		Week 16	86.0	93.0	-7.0
Placebo		Week 16	79.0	77.0	2.0
Placebo		Week 2	72.0	68.0	4.0
Placebo		Week 2	92.0	93.0	-1.0
Placebo		Week 2	92.0	77.0	15.0
Placebo		Week 20	81.0	68.0	13.0
Placebo		Week 20	79.0	93.0	-14.0
Placebo		Week 20	79.0	77.0	2.0
Placebo		Week 24	109.0	68.0	41.0
Placebo		Week 24	117.0	93.0	24.0
Placebo		Week 24	96.0	77.0	19.0
Placebo		Week 26	71.0	68.0	3.0
Placebo		Week 26	66.0	93.0	-27.0
Placebo		Week 26	67.0	77.0	-10.0
Placebo		Week 4	98.0	68.0	30.0
Placebo		Week 4	96.0	93.0	3.0
Placebo		Week 4	100.0	77.0	23.0
Placebo		Week 6	94.0	68.0	26.0
Placebo		Week 6	94.0	93.0	1.0
Placebo		Week 6	98.0	77.0	21.0
Placebo		Week 8	91.0	68.0	23.0
Placebo		Week 8	101.0	93.0	8.0
Placebo		Week 8	101.0	77.0	24.0
Placebo			92.0	68.0
Placebo			88.0	93.0
Placebo			84.0	77.0
Placebo			90.0	68.0
Placebo			90.0	93.0
Placebo			90.0	77.0
Xanomeline High Dose		Week 2	74.0	56.0	18.0
Xanomeline High Dose		Week 2	83.0	73.0	10.0
Xanomeline High Dose		Week 2	70.0	104.0	-34.0
Xanomeline High Dose		Week 4	69.0	56.0	13.0
Xanomeline High Dose		Week 4	76.0	73.0	3.0
Xanomeline High Dose		Week 4	93.0	104.0	-11.0
Xanomeline High Dose		Week 6	53.0	56.0	-3.0
Xanomeline High Dose		Week 6	52.0	73.0	-21.0
Xanomeline High Dose		Week 6	54.0	104.0	-50.0
Xanomeline High Dose		Week 8	61.0	56.0	5.0
Xanomeline High Dose		Week 8	64.0	73.0	-9.0
Xanomeline High Dose		Week 8	59.0	104.0	-45.0
Xanomeline High Dose			56.0	56.0
Xanomeline High Dose			69.0	73.0
Xanomeline High Dose			61.0	104.0
Xanomeline High Dose			70.0	104.0
Xanomeline High Dose		Week 2	72.0	79.0	-7.0
Xanomeline High Dose		Week 2	76.0	76.0	0.0
Xanomeline High Dose		Week 2	77.0	73.0	4.0
Xanomeline High Dose		Week 4	80.0	79.0	1.0
Xanomeline High Dose		Week 4	79.0	76.0	3.0
Xanomeline High Dose		Week 4	83.0	73.0	10.0
Xanomeline High Dose		Week 6	87.0	79.0	8.0
Xanomeline High Dose		Week 6	86.0	76.0	10.0
Xanomeline High Dose		Week 6	87.0	73.0	14.0
Xanomeline High Dose			78.0	79.0
Xanomeline High Dose			79.0	76.0
Xanomeline High Dose			73.0	73.0
Xanomeline High Dose			64.0	79.0
Xanomeline High Dose			72.0	76.0
Xanomeline High Dose			80.0	73.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

MAP

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	91.7	80.7	11.0
Placebo		Week 12	88.7	74.3	14.3
Placebo		Week 12	88.7	84.3	4.3
Placebo		Week 16	98.3	80.7	17.7
Placebo		Week 16	93.7	74.3	19.3
Placebo		Week 16	94.7	84.3	10.3
Placebo		Week 2	75.3	80.7	-5.3
Placebo		Week 2	73.7	74.3	-0.7
Placebo		Week 2	80.0	84.3	-4.3
Placebo		Week 20	90.3	80.7	9.7
Placebo		Week 20	89.7	74.3	15.3
Placebo		Week 20	87.3	84.3	3.0
Placebo		Week 24	85.0	80.7	4.3
Placebo		Week 24	81.7	74.3	7.3
Placebo		Week 24	93.0	84.3	8.7
Placebo		Week 26	83.0	80.7	2.3
Placebo		Week 26	82.0	74.3	7.7
Placebo		Week 26	79.7	84.3	-4.7
Placebo		Week 4	88.7	80.7	8.0
Placebo		Week 4	82.3	74.3	8.0
Placebo		Week 4	79.3	84.3	-5.0
Placebo		Week 6	86.0	80.7	5.3
Placebo		Week 6	87.7	74.3	13.3
Placebo		Week 6	86.0	84.3	1.7
Placebo		Week 8	90.7	80.7	10.0
Placebo		Week 8	90.0	74.3	15.7
Placebo		Week 8	94.0	84.3	9.7
Placebo			90.3	80.7
Placebo			83.0	74.3
Placebo			92.0	84.3
Placebo			94.0	80.7
Placebo			84.3	74.3
Placebo			76.3	84.3
Placebo		Week 2	99.3	99.3	0.0
Placebo		Week 2	100.7	101.3	-0.7
Placebo		Week 2	106.0	102.7	3.3
Placebo			99.0	99.3
Placebo			102.0	101.3
Placebo			105.3	102.7
Xanomeline High Dose		Week 12	92.0	102.7	-10.7
Xanomeline High Dose		Week 12	101.0	99.0	2.0
Xanomeline High Dose		Week 12	99.3	96.3	3.0
Xanomeline High Dose		Week 16	90.7	102.7	-12.0
Xanomeline High Dose		Week 16	94.0	99.0	-5.0
Xanomeline High Dose		Week 16	96.0	96.3	-0.3
Xanomeline High Dose		Week 2	96.7	102.7	-6.0
Xanomeline High Dose		Week 2	99.3	99.0	0.3
Xanomeline High Dose		Week 2	97.0	96.3	0.7
Xanomeline High Dose		Week 20	95.7	102.7	-7.0
Xanomeline High Dose		Week 20	91.7	99.0	-7.3
Xanomeline High Dose		Week 20	95.0	96.3	-1.3
Xanomeline High Dose		Week 24	92.0	102.7	-10.7
Xanomeline High Dose		Week 24	92.3	99.0	-6.7
Xanomeline High Dose		Week 24	95.0	96.3	-1.3
Xanomeline High Dose		Week 26	90.3	102.7	-12.3
Xanomeline High Dose		Week 26	92.0	99.0	-7.0
Xanomeline High Dose		Week 26	95.0	96.3	-1.3
Xanomeline High Dose		Week 4	89.3	102.7	-13.3
Xanomeline High Dose		Week 4	91.3	99.0	-7.7
Xanomeline High Dose		Week 4	91.3	96.3	-5.0
Xanomeline High Dose		Week 6	89.7	102.7	-13.0
Xanomeline High Dose		Week 6	95.0	99.0	-4.0
Xanomeline High Dose		Week 6	94.7	96.3	-1.7
Xanomeline High Dose		Week 8	96.3	102.7	-6.3
Xanomeline High Dose		Week 8	102.7	99.0	3.7
Xanomeline High Dose		Week 8	99.3	96.3	3.0
Xanomeline High Dose			100.7	102.7
Xanomeline High Dose			100.3	99.0
Xanomeline High Dose			104.3	96.3
Xanomeline High Dose			96.7	102.7
Xanomeline High Dose			102.7	99.0
Xanomeline High Dose			102.7	96.3
Xanomeline Low Dose			106.3	100.7
Xanomeline Low Dose			100.3	83.3
Xanomeline Low Dose			103.0	87.0
Xanomeline High Dose		Week 12	95.7	94.3	1.3
Xanomeline High Dose		Week 12	94.0	109.0	-15.0
Xanomeline High Dose		Week 12	101.0	110.7	-9.7
Xanomeline High Dose		Week 16	109.3	94.3	15.0
Xanomeline High Dose		Week 16	112.3	109.0	3.3
Xanomeline High Dose		Week 16	110.0	110.7	-0.7
Xanomeline High Dose		Week 2	115.0	94.3	20.7
Xanomeline High Dose		Week 2	131.0	109.0	22.0
Xanomeline High Dose		Week 2	109.7	110.7	-1.0
Xanomeline High Dose		Week 20	107.7	94.3	13.3
Xanomeline High Dose		Week 20	111.7	109.0	2.7
Xanomeline High Dose		Week 20	109.7	110.7	-1.0
Xanomeline High Dose		Week 24	113.3	94.3	19.0
Xanomeline High Dose		Week 24	130.7	109.0	21.7
Xanomeline High Dose		Week 24	120.0	110.7	9.3
Xanomeline High Dose		Week 26	96.0	94.3	1.7
Xanomeline High Dose		Week 26	112.0	109.0	3.0
Xanomeline High Dose		Week 26	103.7	110.7	-7.0
Xanomeline High Dose		Week 4	102.3	94.3	8.0
Xanomeline High Dose		Week 4	102.7	109.0	-6.3
Xanomeline High Dose		Week 4	103.7	110.7	-7.0
Xanomeline High Dose		Week 6	86.3	94.3	-8.0
Xanomeline High Dose		Week 6	108.7	109.0	-0.3
Xanomeline High Dose		Week 6	110.0	110.7	-0.7
Xanomeline High Dose		Week 8	111.3	94.3	17.0
Xanomeline High Dose		Week 8	119.0	109.0	10.0
Xanomeline High Dose		Week 8	116.7	110.7	6.0
Xanomeline High Dose			82.7	94.3
Xanomeline High Dose			98.7	109.0
Xanomeline High Dose			93.7	110.7
Placebo		Week 2	96.3	91.0	5.3
Placebo		Week 2	104.7	93.7	11.0
Placebo		Week 2	99.7	107.7	-8.0
Placebo			96.7	91.0
Placebo			83.0	93.7
Placebo			98.0	107.7
Xanomeline Low Dose		Week 12	89.7	90.7	-1.0
Xanomeline Low Dose		Week 12	90.7	95.3	-4.7
Xanomeline Low Dose		Week 12	94.3	97.3	-3.0
Xanomeline Low Dose		Week 16	90.7	90.7	0.0
Xanomeline Low Dose		Week 16	96.7	95.3	1.3
Xanomeline Low Dose		Week 16	95.7	97.3	-1.7
Xanomeline Low Dose		Week 2	89.3	90.7	-1.3
Xanomeline Low Dose		Week 2	98.0	95.3	2.7
Xanomeline Low Dose		Week 2	100.0	97.3	2.7
Xanomeline Low Dose		Week 20	85.0	90.7	-5.7
Xanomeline Low Dose		Week 20	76.0	95.3	-19.3
Xanomeline Low Dose		Week 20	79.0	97.3	-18.3
Xanomeline Low Dose		Week 24	101.0	90.7	10.3
Xanomeline Low Dose		Week 24	99.7	95.3	4.3
Xanomeline Low Dose		Week 24	99.3	97.3	2.0
Xanomeline Low Dose		Week 26	89.0	90.7	-1.7
Xanomeline Low Dose		Week 26	96.0	95.3	0.7
Xanomeline Low Dose		Week 26	95.0	97.3	-2.3
Xanomeline Low Dose		Week 4	93.0	90.7	2.3
Xanomeline Low Dose		Week 4	91.3	95.3	-4.0
Xanomeline Low Dose		Week 4	91.0	97.3	-6.3
Xanomeline Low Dose		Week 6	86.0	90.7	-4.7
Xanomeline Low Dose		Week 6	88.0	95.3	-7.3
Xanomeline Low Dose		Week 6	93.3	97.3	-4.0
Xanomeline Low Dose		Week 8	95.3	90.7	4.7
Xanomeline Low Dose		Week 8	92.0	95.3	-3.3
Xanomeline Low Dose		Week 8	87.7	97.3	-9.7
Xanomeline Low Dose			85.0	90.7
Xanomeline Low Dose			100.7	95.3
Xanomeline Low Dose			88.0	97.3
Xanomeline Low Dose			89.3	90.7
Xanomeline Low Dose			90.7	95.3
Xanomeline Low Dose			92.7	97.3
Xanomeline Low Dose		Week 2	93.3	98.7	-5.3
Xanomeline Low Dose		Week 2	85.0	80.0	5.0
Xanomeline Low Dose		Week 2	79.3	82.7	-3.3
Xanomeline Low Dose		Week 4	83.7	98.7	-15.0
Xanomeline Low Dose		Week 4	68.0	80.0	-12.0
Xanomeline Low Dose		Week 4	69.0	82.7	-13.7
Xanomeline Low Dose		Week 6	95.0	98.7	-3.7
Xanomeline Low Dose		Week 6	83.0	80.0	3.0
Xanomeline Low Dose		Week 6	80.7	82.7	-2.0
Xanomeline Low Dose		Week 8	91.7	98.7	-7.0
Xanomeline Low Dose		Week 8	72.3	80.0	-7.7
Xanomeline Low Dose		Week 8	72.7	82.7	-10.0
Xanomeline Low Dose			100.0	98.7
Xanomeline Low Dose			86.7	80.0
Xanomeline Low Dose			86.7	82.7
Xanomeline Low Dose			86.7	98.7
Xanomeline Low Dose			72.7	80.0
Xanomeline Low Dose			66.3	82.7
Placebo		Week 12	89.0	101.7	-12.7
Placebo		Week 12	88.7	95.7	-7.0
Placebo		Week 12	91.3	97.0	-5.7
Placebo		Week 16	88.7	101.7	-13.0
Placebo		Week 16	86.0	95.7	-9.7
Placebo		Week 16	83.3	97.0	-13.7
Placebo		Week 2	97.7	101.7	-4.0
Placebo		Week 2	88.3	95.7	-7.3
Placebo		Week 2	92.3	97.0	-4.7
Placebo		Week 20	100.0	101.7	-1.7
Placebo		Week 20	108.0	95.7	12.3
Placebo		Week 20	104.3	97.0	7.3
Placebo		Week 24	94.0	101.7	-7.7
Placebo		Week 24	83.7	95.7	-12.0
Placebo		Week 24	87.3	97.0	-9.7
Placebo		Week 26	89.7	101.7	-12.0
Placebo		Week 26	82.3	95.7	-13.3
Placebo		Week 26	88.7	97.0	-8.3
Placebo		Week 4	93.3	101.7	-8.3
Placebo		Week 4	83.3	95.7	-12.3
Placebo		Week 4	96.7	97.0	-0.3
Placebo		Week 6	84.3	101.7	-17.3
Placebo		Week 6	86.0	95.7	-9.7
Placebo		Week 6	86.0	97.0	-11.0
Placebo		Week 8	86.7	101.7	-15.0
Placebo		Week 8	83.3	95.7	-12.3
Placebo		Week 8	92.3	97.0	-4.7
Placebo			94.3	101.7
Placebo			94.7	95.7
Placebo			102.7	97.0
Placebo			93.3	101.7
Placebo			86.0	95.7
Placebo			93.3	97.0
Placebo		Week 12	82.7	90.0	-7.3
Placebo		Week 12	79.0	85.3	-6.3
Placebo		Week 12	88.7	88.7	0.0
Placebo		Week 16	91.7	90.0	1.7
Placebo		Week 16	95.7	85.3	10.3
Placebo		Week 16	102.3	88.7	13.7
Placebo		Week 2	89.0	90.0	-1.0
Placebo		Week 2	89.7	85.3	4.3
Placebo		Week 2	84.3	88.7	-4.3
Placebo		Week 20	80.0	90.0	-10.0
Placebo		Week 20	78.3	85.3	-7.0
Placebo		Week 20	80.7	88.7	-8.0
Placebo		Week 24	92.0	90.0	2.0
Placebo		Week 24	92.0	85.3	6.7
Placebo		Week 24	99.7	88.7	11.0
Placebo		Week 26	93.3	90.0	3.3
Placebo		Week 26	104.0	85.3	18.7
Placebo		Week 26	107.7	88.7	19.0
Placebo		Week 4	82.7	90.0	-7.3
Placebo		Week 4	94.3	85.3	9.0
Placebo		Week 4	89.0	88.7	0.3
Placebo		Week 6	83.7	90.0	-6.3
Placebo		Week 6	87.0	85.3	1.7
Placebo		Week 6	92.7	88.7	4.0
Placebo		Week 8	98.3	90.0	8.3
Placebo		Week 8	91.3	85.3	6.0
Placebo		Week 8	99.3	88.7	10.7
Placebo			98.3	90.0
Placebo			94.0	85.3
Placebo			92.3	88.7
Placebo			83.7	90.0
Placebo			83.7	85.3
Placebo			90.7	88.7
Xanomeline High Dose		Week 12	80.3	92.7	-12.3
Xanomeline High Dose		Week 12	88.3	83.3	5.0
Xanomeline High Dose		Week 12	88.7	87.3	1.3
Xanomeline High Dose		Week 16	93.7	92.7	1.0
Xanomeline High Dose		Week 16	91.0	83.3	7.7
Xanomeline High Dose		Week 16	100.7	87.3	13.3
Xanomeline High Dose		Week 2	93.7	92.7	1.0
Xanomeline High Dose		Week 2	85.0	83.3	1.7
Xanomeline High Dose		Week 2	90.7	87.3	3.3
Xanomeline High Dose		Week 20	104.3	92.7	11.7
Xanomeline High Dose		Week 20	91.3	83.3	8.0
Xanomeline High Dose		Week 20	86.0	87.3	-1.3
Xanomeline High Dose		Week 24	97.7	92.7	5.0
Xanomeline High Dose		Week 24	88.3	83.3	5.0
Xanomeline High Dose		Week 24	86.0	87.3	-1.3
Xanomeline High Dose		Week 4	106.3	92.7	13.7
Xanomeline High Dose		Week 4	100.3	83.3	17.0
Xanomeline High Dose		Week 4	92.0	87.3	4.7
Xanomeline High Dose		Week 6	90.3	92.7	-2.3
Xanomeline High Dose		Week 6	82.3	83.3	-1.0
Xanomeline High Dose		Week 6	82.3	87.3	-5.0
Xanomeline High Dose		Week 8	87.7	92.7	-5.0
Xanomeline High Dose		Week 8	88.7	83.3	5.3
Xanomeline High Dose		Week 8	86.0	87.3	-1.3
Xanomeline High Dose			83.0	92.7
Xanomeline High Dose			82.3	83.3
Xanomeline High Dose			81.3	87.3
Xanomeline High Dose			94.0	92.7
Xanomeline High Dose			83.3	83.3
Xanomeline High Dose			88.7	87.3
Xanomeline High Dose		Week 2	74.0	76.7	-2.7
Xanomeline High Dose		Week 2	63.3	79.3	-16.0
Xanomeline High Dose		Week 2	77.3	72.3	5.0
Xanomeline High Dose		Week 4	77.0	76.7	0.3
Xanomeline High Dose		Week 4	82.3	79.3	3.0
Xanomeline High Dose		Week 4	78.0	72.3	5.7
Xanomeline High Dose			71.7	76.7
Xanomeline High Dose			80.0	79.3
Xanomeline High Dose			81.7	72.3
Xanomeline High Dose			66.0	76.7
Xanomeline High Dose			78.3	79.3
Xanomeline High Dose			78.0	72.3
Xanomeline High Dose		Week 12	83.3	85.3	-2.0
Xanomeline High Dose		Week 12	81.7	77.3	4.3
Xanomeline High Dose		Week 12	82.0	91.3	-9.3
Xanomeline High Dose		Week 16	83.3	85.3	-2.0
Xanomeline High Dose		Week 16	84.3	77.3	7.0
Xanomeline High Dose		Week 16	87.0	91.3	-4.3
Xanomeline High Dose		Week 2	86.7	85.3	1.3
Xanomeline High Dose		Week 2	81.7	77.3	4.3
Xanomeline High Dose		Week 2	87.0	91.3	-4.3
Xanomeline High Dose		Week 20	84.7	85.3	-0.7
Xanomeline High Dose		Week 20	77.0	77.3	-0.3
Xanomeline High Dose		Week 20	80.0	91.3	-11.3
Xanomeline High Dose		Week 24	76.3	85.3	-9.0
Xanomeline High Dose		Week 24	80.7	77.3	3.3
Xanomeline High Dose		Week 24	82.0	91.3	-9.3
Xanomeline High Dose		Week 26	81.0	85.3	-4.3
Xanomeline High Dose		Week 26	81.7	77.3	4.3
Xanomeline High Dose		Week 26	77.0	91.3	-14.3
Xanomeline High Dose		Week 4	84.3	85.3	-1.0
Xanomeline High Dose		Week 4	77.0	77.3	-0.3
Xanomeline High Dose		Week 4	72.3	91.3	-19.0
Xanomeline High Dose		Week 6	89.0	85.3	3.7
Xanomeline High Dose		Week 6	75.3	77.3	-2.0
Xanomeline High Dose		Week 6	82.7	91.3	-8.7
Xanomeline High Dose		Week 8	90.7	85.3	5.3
Xanomeline High Dose		Week 8	86.7	77.3	9.3
Xanomeline High Dose		Week 8	90.0	91.3	-1.3
Xanomeline High Dose			97.3	85.3
Xanomeline High Dose			84.7	77.3
Xanomeline High Dose			83.7	91.3
Xanomeline High Dose			91.7	85.3
Xanomeline High Dose			90.0	77.3
Xanomeline High Dose			92.0	91.3
Placebo		Week 12	95.7	87.3	8.3
Placebo		Week 12	90.7	87.0	3.7
Placebo		Week 12	88.3	86.0	2.3
Placebo		Week 16	91.3	87.3	4.0
Placebo		Week 16	85.7	87.0	-1.3
Placebo		Week 16	88.7	86.0	2.7
Placebo		Week 2	89.3	87.3	2.0
Placebo		Week 2	86.0	87.0	-1.0
Placebo		Week 2	91.7	86.0	5.7
Placebo		Week 20	84.0	87.3	-3.3
Placebo		Week 20	84.0	87.0	-3.0
Placebo		Week 20	86.7	86.0	0.7
Placebo		Week 24	87.7	87.3	0.3
Placebo		Week 24	81.3	87.0	-5.7
Placebo		Week 24	87.0	86.0	1.0
Placebo		Week 4	83.3	87.3	-4.0
Placebo		Week 4	80.0	87.0	-7.0
Placebo		Week 4	86.7	86.0	0.7
Placebo		Week 6	87.7	87.3	0.3
Placebo		Week 6	95.7	87.0	8.7
Placebo		Week 6	99.3	86.0	13.3
Placebo		Week 8	85.3	87.3	-2.0
Placebo		Week 8	90.3	87.0	3.3
Placebo		Week 8	86.0	86.0	0.0
Placebo			96.7	87.3
Placebo			91.3	87.0
Placebo			98.0	86.0
Placebo			86.3	87.3
Placebo			75.3	87.0
Placebo			80.0	86.0
Xanomeline High Dose		Week 2	104.0	94.7	9.3
Xanomeline High Dose		Week 2	104.0	96.7	7.3
Xanomeline High Dose		Week 2	109.3	99.3	10.0
Xanomeline High Dose		Week 4	94.0	94.7	-0.7
Xanomeline High Dose		Week 4	93.7	96.7	-3.0
Xanomeline High Dose		Week 4	98.3	99.3	-1.0
Xanomeline High Dose			108.7	94.7
Xanomeline High Dose			107.7	96.7
Xanomeline High Dose			112.0	99.3
Xanomeline High Dose			97.3	94.7
Xanomeline High Dose			96.7	96.7
Xanomeline High Dose			94.3	99.3
Xanomeline Low Dose		Week 2	107.0	97.0	10.0
Xanomeline Low Dose		Week 2	95.0	85.3	9.7
Xanomeline Low Dose		Week 2	97.7	88.7	9.0
Xanomeline Low Dose		Week 4	101.7	97.0	4.7
Xanomeline Low Dose		Week 4	99.7	85.3	14.3
Xanomeline Low Dose		Week 4	100.0	88.7	11.3
Xanomeline Low Dose			93.3	97.0
Xanomeline Low Dose			89.7	85.3
Xanomeline Low Dose			95.0	88.7
Xanomeline Low Dose			104.7	97.0
Xanomeline Low Dose			100.3	85.3
Xanomeline Low Dose			101.3	88.7
Xanomeline Low Dose		Week 12	87.3	110.0	-22.7
Xanomeline Low Dose		Week 12	90.7	103.3	-12.7
Xanomeline Low Dose		Week 12	96.0	106.7	-10.7
Xanomeline Low Dose		Week 16	103.3	110.0	-6.7
Xanomeline Low Dose		Week 16	92.7	103.3	-10.7
Xanomeline Low Dose		Week 16	105.0	106.7	-1.7
Xanomeline Low Dose		Week 2	107.3	110.0	-2.7
Xanomeline Low Dose		Week 2	106.0	103.3	2.7
Xanomeline Low Dose		Week 2	101.7	106.7	-5.0
Xanomeline Low Dose		Week 20	90.0	110.0	-20.0
Xanomeline Low Dose		Week 20	108.0	103.3	4.7
Xanomeline Low Dose		Week 20	108.7	106.7	2.0
Xanomeline Low Dose		Week 24	114.3	110.0	4.3
Xanomeline Low Dose		Week 24	108.0	103.3	4.7
Xanomeline Low Dose		Week 24	114.7	106.7	8.0
Xanomeline Low Dose		Week 26	113.0	110.0	3.0
Xanomeline Low Dose		Week 26	114.0	103.3	10.7
Xanomeline Low Dose		Week 26	111.7	106.7	5.0
Xanomeline Low Dose		Week 4	103.3	110.0	-6.7
Xanomeline Low Dose		Week 4	90.7	103.3	-12.7
Xanomeline Low Dose		Week 4	105.3	106.7	-1.3
Xanomeline Low Dose		Week 6	94.0	110.0	-16.0
Xanomeline Low Dose		Week 6	102.7	103.3	-0.7
Xanomeline Low Dose		Week 6	96.7	106.7	-10.0
Xanomeline Low Dose		Week 8	88.3	110.0	-21.7
Xanomeline Low Dose		Week 8	80.7	103.3	-22.7
Xanomeline Low Dose		Week 8	90.7	106.7	-16.0
Xanomeline Low Dose			110.0	110.0
Xanomeline Low Dose			106.7	103.3
Xanomeline Low Dose			102.7	106.7
Xanomeline Low Dose			98.0	110.0
Xanomeline Low Dose			108.0	103.3
Xanomeline Low Dose			104.7	106.7
Placebo		Week 12	71.7	69.7	2.0
Placebo		Week 12	65.0	85.7	-20.7
Placebo		Week 12	76.7	76.7	0.0
Placebo		Week 16	86.3	69.7	16.7
Placebo		Week 16	78.7	85.7	-7.0
Placebo		Week 16	76.7	76.7	0.0
Placebo		Week 2	75.3	69.7	5.7
Placebo		Week 2	84.3	85.7	-1.3
Placebo		Week 2	84.0	76.7	7.3
Placebo		Week 20	80.7	69.7	11.0
Placebo		Week 20	79.0	85.7	-6.7
Placebo		Week 20	83.7	76.7	7.0
Placebo		Week 24	71.0	69.7	1.3
Placebo		Week 24	68.0	85.7	-17.7
Placebo		Week 24	85.3	76.7	8.7
Placebo		Week 26	79.7	69.7	10.0
Placebo		Week 26	64.0	85.7	-21.7
Placebo		Week 26	78.3	76.7	1.7
Placebo		Week 4	70.0	69.7	0.3
Placebo		Week 4	78.7	85.7	-7.0
Placebo		Week 4	74.0	76.7	-2.7
Placebo		Week 6	87.0	69.7	17.3
Placebo		Week 6	90.7	85.7	5.0
Placebo		Week 6	84.0	76.7	7.3
Placebo		Week 8	84.3	69.7	14.7
Placebo		Week 8	81.3	85.7	-4.3
Placebo		Week 8	88.3	76.7	11.7
Placebo			70.7	69.7
Placebo			73.3	85.7
Placebo			76.0	76.7
Xanomeline Low Dose		Week 2	76.3	87.7	-11.3
Xanomeline Low Dose		Week 2	72.0	77.3	-5.3
Xanomeline Low Dose		Week 2	74.7	69.3	5.3
Xanomeline Low Dose		Week 4	75.0	87.7	-12.7
Xanomeline Low Dose		Week 4	73.3	77.3	-4.0
Xanomeline Low Dose		Week 4	72.7	69.3	3.3
Xanomeline Low Dose		Week 6	81.0	87.7	-6.7
Xanomeline Low Dose		Week 6	86.3	77.3	9.0
Xanomeline Low Dose		Week 6	79.0	69.3	9.7
Xanomeline Low Dose		Week 8	91.3	87.7	3.7
Xanomeline Low Dose		Week 8	81.3	77.3	4.0
Xanomeline Low Dose		Week 8	87.7	69.3	18.3
Xanomeline Low Dose			95.3	87.7
Xanomeline Low Dose			81.0	77.3
Xanomeline Low Dose			96.7	69.3
Xanomeline Low Dose			86.0	87.7
Xanomeline Low Dose			57.0	77.3
Xanomeline Low Dose			78.0	69.3
Placebo		Week 12	96.3	96.7	-0.3
Placebo		Week 12	107.7	95.3	12.3
Placebo		Week 12	106.7	98.0	8.7
Placebo		Week 16	98.0	96.7	1.3
Placebo		Week 16	98.0	95.3	2.7
Placebo		Week 16	113.0	98.0	15.0
Placebo		Week 2	108.0	96.7	11.3
Placebo		Week 2	109.7	95.3	14.3
Placebo		Week 2	105.3	98.0	7.3
Placebo		Week 20	94.7	96.7	-2.0
Placebo		Week 20	84.0	95.3	-11.3
Placebo		Week 20	90.3	98.0	-7.7
Placebo		Week 24	89.0	96.7	-7.7
Placebo		Week 24	90.0	95.3	-5.3
Placebo		Week 24	91.7	98.0	-6.3
Placebo		Week 26	115.3	96.7	18.7
Placebo		Week 26	112.0	95.3	16.7
Placebo		Week 26	110.0	98.0	12.0
Placebo		Week 4	99.0	96.7	2.3
Placebo		Week 4	104.3	95.3	9.0
Placebo		Week 4	106.3	98.0	8.3
Placebo		Week 6	94.3	96.7	-2.3
Placebo		Week 6	97.7	95.3	2.3
Placebo		Week 6	99.7	98.0	1.7
Placebo		Week 8	97.3	96.7	0.7
Placebo		Week 8	96.0	95.3	0.7
Placebo		Week 8	103.0	98.0	5.0
Placebo			108.7	96.7
Placebo			102.7	95.3
Placebo			109.3	98.0
Placebo			100.0	96.7
Placebo			97.3	95.3
Placebo			102.0	98.0
Xanomeline High Dose		Week 12	104.0	109.0	-5.0
Xanomeline High Dose		Week 12	100.0	106.0	-6.0
Xanomeline High Dose		Week 12	104.0	108.7	-4.7
Xanomeline High Dose		Week 16	103.0	109.0	-6.0
Xanomeline High Dose		Week 16	93.0	106.0	-13.0
Xanomeline High Dose		Week 16	100.3	108.7	-8.3
Xanomeline High Dose		Week 2	101.3	109.0	-7.7
Xanomeline High Dose		Week 2	98.3	106.0	-7.7
Xanomeline High Dose		Week 2	106.3	108.7	-2.3
Xanomeline High Dose		Week 20	104.3	109.0	-4.7
Xanomeline High Dose		Week 20	104.0	106.0	-2.0
Xanomeline High Dose		Week 20	97.7	108.7	-11.0
Xanomeline High Dose		Week 24	105.0	109.0	-4.0
Xanomeline High Dose		Week 24	93.0	106.0	-13.0
Xanomeline High Dose		Week 24	101.7	108.7	-7.0
Xanomeline High Dose		Week 4	102.7	109.0	-6.3
Xanomeline High Dose		Week 4	103.0	106.0	-3.0
Xanomeline High Dose		Week 4	102.3	108.7	-6.3
Xanomeline High Dose		Week 6	102.0	109.0	-7.0
Xanomeline High Dose		Week 6	94.7	106.0	-11.3
Xanomeline High Dose		Week 6	91.3	108.7	-17.3
Xanomeline High Dose		Week 8	103.3	109.0	-5.7
Xanomeline High Dose		Week 8	94.7	106.0	-11.3
Xanomeline High Dose		Week 8	100.3	108.7	-8.3
Xanomeline High Dose			110.3	109.0
Xanomeline High Dose			104.7	106.0
Xanomeline High Dose			108.7	108.7
Xanomeline High Dose			113.0	109.0
Xanomeline High Dose			109.7	106.0
Xanomeline High Dose			99.7	108.7
Xanomeline High Dose		Week 12	86.3	96.7	-10.3
Xanomeline High Dose		Week 12	95.0	102.7	-7.7
Xanomeline High Dose		Week 12	97.7	100.0	-2.3
Xanomeline High Dose		Week 2	84.3	96.7	-12.3
Xanomeline High Dose		Week 2	94.7	102.7	-8.0
Xanomeline High Dose		Week 2	94.3	100.0	-5.7
Xanomeline High Dose		Week 4	96.0	96.7	-0.7
Xanomeline High Dose		Week 4	91.7	102.7	-11.0
Xanomeline High Dose		Week 4	97.3	100.0	-2.7
Xanomeline High Dose		Week 6	88.7	96.7	-8.0
Xanomeline High Dose		Week 6	83.7	102.7	-19.0
Xanomeline High Dose		Week 6	90.7	100.0	-9.3
Xanomeline High Dose		Week 8	94.7	96.7	-2.0
Xanomeline High Dose		Week 8	97.7	102.7	-5.0
Xanomeline High Dose		Week 8	99.3	100.0	-0.7
Xanomeline High Dose			90.3	96.7
Xanomeline High Dose			82.0	102.7
Xanomeline High Dose			97.7	100.0
Xanomeline High Dose			97.3	96.7
Xanomeline High Dose			93.3	102.7
Xanomeline High Dose			99.3	100.0
Xanomeline High Dose		Week 12	81.0	83.3	-2.3
Xanomeline High Dose		Week 12	86.3	87.0	-0.7
Xanomeline High Dose		Week 12	80.0	82.7	-2.7
Xanomeline High Dose		Week 16	95.0	83.3	11.7
Xanomeline High Dose		Week 16	88.0	87.0	1.0
Xanomeline High Dose		Week 16	89.0	82.7	6.3
Xanomeline High Dose		Week 2	89.3	83.3	6.0
Xanomeline High Dose		Week 2	80.0	87.0	-7.0
Xanomeline High Dose		Week 2	89.3	82.7	6.7
Xanomeline High Dose		Week 20	83.7	83.3	0.3
Xanomeline High Dose		Week 20	85.3	87.0	-1.7
Xanomeline High Dose		Week 20	88.0	82.7	5.3
Xanomeline High Dose		Week 24	88.0	83.3	4.7
Xanomeline High Dose		Week 24	91.7	87.0	4.7
Xanomeline High Dose		Week 24	94.3	82.7	11.7
Xanomeline High Dose		Week 26	79.0	83.3	-4.3
Xanomeline High Dose		Week 26	89.7	87.0	2.7
Xanomeline High Dose		Week 26	90.3	82.7	7.7
Xanomeline High Dose		Week 4	84.0	83.3	0.7
Xanomeline High Dose		Week 4	87.7	87.0	0.7
Xanomeline High Dose		Week 4	79.7	82.7	-3.0
Xanomeline High Dose		Week 6	93.3	83.3	10.0
Xanomeline High Dose		Week 6	95.0	87.0	8.0
Xanomeline High Dose		Week 6	94.0	82.7	11.3
Xanomeline High Dose		Week 8	80.0	83.3	-3.3
Xanomeline High Dose		Week 8	73.0	87.0	-14.0
Xanomeline High Dose		Week 8	82.0	82.7	-0.7
Xanomeline High Dose			86.0	83.3
Xanomeline High Dose			93.0	87.0
Xanomeline High Dose			86.0	82.7
Xanomeline Low Dose		Week 12	97.0	101.0	-4.0
Xanomeline Low Dose		Week 12	89.3	89.7	-0.3
Xanomeline Low Dose		Week 12	88.0	95.0	-7.0
Xanomeline Low Dose		Week 2	99.3	101.0	-1.7
Xanomeline Low Dose		Week 2	99.7	89.7	10.0
Xanomeline Low Dose		Week 2	94.3	95.0	-0.7
Xanomeline Low Dose		Week 4	99.3	101.0	-1.7
Xanomeline Low Dose		Week 4	98.3	89.7	8.7
Xanomeline Low Dose		Week 4	94.3	95.0	-0.7
Xanomeline Low Dose		Week 6	101.3	101.0	0.3
Xanomeline Low Dose		Week 6	94.0	89.7	4.3
Xanomeline Low Dose		Week 6	99.7	95.0	4.7
Xanomeline Low Dose		Week 8	93.0	101.0	-8.0
Xanomeline Low Dose		Week 8	92.7	89.7	3.0
Xanomeline Low Dose		Week 8	92.3	95.0	-2.7
Xanomeline Low Dose			96.3	101.0
Xanomeline Low Dose			96.7	89.7
Xanomeline Low Dose			94.0	95.0
Xanomeline Low Dose			96.3	101.0
Xanomeline Low Dose			91.7	89.7
Xanomeline Low Dose			95.3	95.0
Xanomeline High Dose		Week 12	89.0	94.3	-5.3
Xanomeline High Dose		Week 12	95.3	103.7	-8.3
Xanomeline High Dose		Week 12	97.7	100.7	-3.0
Xanomeline High Dose		Week 2	85.3	94.3	-9.0
Xanomeline High Dose		Week 2	90.7	103.7	-13.0
Xanomeline High Dose		Week 2	97.0	100.7	-3.7
Xanomeline High Dose		Week 4	91.7	94.3	-2.7
Xanomeline High Dose		Week 4	91.7	103.7	-12.0
Xanomeline High Dose		Week 4	97.0	100.7	-3.7
Xanomeline High Dose		Week 6	79.3	94.3	-15.0
Xanomeline High Dose		Week 6	85.0	103.7	-18.7
Xanomeline High Dose		Week 6	91.7	100.7	-9.0
Xanomeline High Dose		Week 8	89.7	94.3	-4.7
Xanomeline High Dose		Week 8	94.3	103.7	-9.3
Xanomeline High Dose		Week 8	98.7	100.7	-2.0
Xanomeline High Dose			87.0	94.3
Xanomeline High Dose			94.3	103.7
Xanomeline High Dose			94.3	100.7
Xanomeline High Dose			97.7	94.3
Xanomeline High Dose			91.7	103.7
Xanomeline High Dose			92.0	100.7
Xanomeline Low Dose		Week 12	88.3	88.0	0.3
Xanomeline Low Dose		Week 12	82.0	81.0	1.0
Xanomeline Low Dose		Week 12	81.0	83.7	-2.7
Xanomeline Low Dose		Week 16	91.0	88.0	3.0
Xanomeline Low Dose		Week 16	89.0	81.0	8.0
Xanomeline Low Dose		Week 16	91.7	83.7	8.0
Xanomeline Low Dose		Week 2	100.3	88.0	12.3
Xanomeline Low Dose		Week 2	90.0	81.0	9.0
Xanomeline Low Dose		Week 2	94.3	83.7	10.7
Xanomeline Low Dose		Week 20	88.7	88.0	0.7
Xanomeline Low Dose		Week 20	79.3	81.0	-1.7
Xanomeline Low Dose		Week 20	79.3	83.7	-4.3
Xanomeline Low Dose		Week 24	90.7	88.0	2.7
Xanomeline Low Dose		Week 24	89.0	81.0	8.0
Xanomeline Low Dose		Week 24	89.3	83.7	5.7
Xanomeline Low Dose		Week 26	86.3	88.0	-1.7
Xanomeline Low Dose		Week 26	76.3	81.0	-4.7
Xanomeline Low Dose		Week 26	78.7	83.7	-5.0
Xanomeline Low Dose		Week 4	84.7	88.0	-3.3
Xanomeline Low Dose		Week 4	84.3	81.0	3.3
Xanomeline Low Dose		Week 4	79.0	83.7	-4.7
Xanomeline Low Dose		Week 6	90.7	88.0	2.7
Xanomeline Low Dose		Week 6	89.0	81.0	8.0
Xanomeline Low Dose		Week 6	85.0	83.7	1.3
Xanomeline Low Dose		Week 8	88.7	88.0	0.7
Xanomeline Low Dose		Week 8	81.0	81.0	0.0
Xanomeline Low Dose		Week 8	79.0	83.7	-4.7
Xanomeline Low Dose			101.0	88.0
Xanomeline Low Dose			91.3	81.0
Xanomeline Low Dose			90.0	83.7
Xanomeline Low Dose			91.7	88.0
Xanomeline Low Dose			87.3	81.0
Xanomeline Low Dose			81.7	83.7
Xanomeline Low Dose		Week 12	77.7	87.3	-9.7
Xanomeline Low Dose		Week 12	74.3	81.3	-7.0
Xanomeline Low Dose		Week 12	78.7	81.3	-2.7
Xanomeline Low Dose		Week 16	81.3	87.3	-6.0
Xanomeline Low Dose		Week 16	74.7	81.3	-6.7
Xanomeline Low Dose		Week 16	79.3	81.3	-2.0
Xanomeline Low Dose		Week 2	78.3	87.3	-9.0
Xanomeline Low Dose		Week 2	79.3	81.3	-2.0
Xanomeline Low Dose		Week 2	76.3	81.3	-5.0
Xanomeline Low Dose		Week 20	74.7	87.3	-12.7
Xanomeline Low Dose		Week 20	70.0	81.3	-11.3
Xanomeline Low Dose		Week 20	73.0	81.3	-8.3
Xanomeline Low Dose		Week 24	76.3	87.3	-11.0
Xanomeline Low Dose		Week 24	74.3	81.3	-7.0
Xanomeline Low Dose		Week 24	71.7	81.3	-9.7
Xanomeline Low Dose		Week 26	73.7	87.3	-13.7
Xanomeline Low Dose		Week 26	73.3	81.3	-8.0
Xanomeline Low Dose		Week 26	74.0	81.3	-7.3
Xanomeline Low Dose		Week 4	83.3	87.3	-4.0
Xanomeline Low Dose		Week 4	82.7	81.3	1.3
Xanomeline Low Dose		Week 4	78.0	81.3	-3.3
Xanomeline Low Dose		Week 6	86.0	87.3	-1.3
Xanomeline Low Dose		Week 6	79.3	81.3	-2.0
Xanomeline Low Dose		Week 6	80.0	81.3	-1.3
Xanomeline Low Dose		Week 8	73.0	87.3	-14.3
Xanomeline Low Dose		Week 8	75.7	81.3	-5.7
Xanomeline Low Dose		Week 8	77.0	81.3	-4.3
Xanomeline Low Dose			87.7	87.3
Xanomeline Low Dose			82.7	81.3
Xanomeline Low Dose			81.0	81.3
Xanomeline Low Dose			84.0	87.3
Xanomeline Low Dose			84.0	81.3
Xanomeline Low Dose			85.3	81.3
Xanomeline Low Dose		Week 2	113.3	105.7	7.7
Xanomeline Low Dose		Week 2	116.3	113.3	3.0
Xanomeline Low Dose		Week 2	115.7	112.0	3.7
Xanomeline Low Dose			104.7	105.7
Xanomeline Low Dose			115.7	113.3
Xanomeline Low Dose			108.3	112.0
Placebo		Week 12	77.0	80.7	-3.7
Placebo		Week 12	70.3	70.7	-0.3
Placebo		Week 12	78.3	74.7	3.7
Placebo		Week 16	74.7	80.7	-6.0
Placebo		Week 16	70.7	70.7	0.0
Placebo		Week 16	77.7	74.7	3.0
Placebo		Week 2	73.3	80.7	-7.3
Placebo		Week 2	74.0	70.7	3.3
Placebo		Week 2	78.0	74.7	3.3
Placebo		Week 20	73.7	80.7	-7.0
Placebo		Week 20	66.7	70.7	-4.0
Placebo		Week 20	78.0	74.7	3.3
Placebo		Week 24	72.7	80.7	-8.0
Placebo		Week 24	77.3	70.7	6.7
Placebo		Week 24	71.7	74.7	-3.0
Placebo		Week 4	65.0	80.7	-15.7
Placebo		Week 4	61.3	70.7	-9.3
Placebo		Week 4	74.3	74.7	-0.3
Placebo		Week 6	75.0	80.7	-5.7
Placebo		Week 6	75.3	70.7	4.7
Placebo		Week 6	74.3	74.7	-0.3
Placebo		Week 8	71.0	80.7	-9.7
Placebo		Week 8	69.7	70.7	-1.0
Placebo		Week 8	74.0	74.7	-0.7
Placebo			74.0	80.7
Placebo			74.3	70.7
Placebo			76.7	74.7
Placebo			68.7	80.7
Placebo			70.0	70.7
Placebo			75.3	74.7
Placebo		Week 12	75.7	82.0	-6.3
Placebo		Week 12	87.3	88.7	-1.3
Placebo		Week 12	80.3	78.3	2.0
Placebo		Week 16	96.0	82.0	14.0
Placebo		Week 16	87.0	88.7	-1.7
Placebo		Week 16	90.0	78.3	11.7
Placebo		Week 2	79.7	82.0	-2.3
Placebo		Week 2	69.7	88.7	-19.0
Placebo		Week 2	65.7	78.3	-12.7
Placebo		Week 20	75.3	82.0	-6.7
Placebo		Week 20	78.0	88.7	-10.7
Placebo		Week 20	66.0	78.3	-12.3
Placebo		Week 24	85.3	82.0	3.3
Placebo		Week 24	91.3	88.7	2.7
Placebo		Week 24	78.0	78.3	-0.3
Placebo		Week 26	64.0	82.0	-18.0
Placebo		Week 26	76.3	88.7	-12.3
Placebo		Week 26	75.7	78.3	-2.7
Placebo		Week 4	72.0	82.0	-10.0
Placebo		Week 4	68.7	88.7	-20.0
Placebo		Week 4	72.3	78.3	-6.0
Placebo		Week 6	73.0	82.0	-9.0
Placebo		Week 6	70.7	88.7	-18.0
Placebo		Week 6	69.0	78.3	-9.3
Placebo		Week 8	85.0	82.0	3.0
Placebo		Week 8	78.3	88.7	-10.3
Placebo		Week 8	87.0	78.3	8.7
Placebo			68.7	82.0
Placebo			80.0	88.7
Placebo			79.7	78.3
Placebo			72.7	82.0
Placebo			67.3	88.7
Placebo			64.3	78.3
Xanomeline High Dose		Week 12	75.3	87.7	-12.3
Xanomeline High Dose		Week 12	80.7	86.0	-5.3
Xanomeline High Dose		Week 12	80.7	87.0	-6.3
Xanomeline High Dose		Week 16	87.3	87.7	-0.3
Xanomeline High Dose		Week 16	83.3	86.0	-2.7
Xanomeline High Dose		Week 16	89.3	87.0	2.3
Xanomeline High Dose		Week 2	90.0	87.7	2.3
Xanomeline High Dose		Week 2	80.7	86.0	-5.3
Xanomeline High Dose		Week 2	90.0	87.0	3.0
Xanomeline High Dose		Week 20	82.3	87.7	-5.3
Xanomeline High Dose		Week 20	82.3	86.0	-3.7
Xanomeline High Dose		Week 20	88.0	87.0	1.0
Xanomeline High Dose		Week 24	92.7	87.7	5.0
Xanomeline High Dose		Week 24	82.7	86.0	-3.3
Xanomeline High Dose		Week 24	85.3	87.0	-1.7
Xanomeline High Dose		Week 26	84.7	87.7	-3.0
Xanomeline High Dose		Week 26	75.7	86.0	-10.3
Xanomeline High Dose		Week 26	80.3	87.0	-6.7
Xanomeline High Dose		Week 4	80.0	87.7	-7.7
Xanomeline High Dose		Week 4	80.3	86.0	-5.7
Xanomeline High Dose		Week 4	88.7	87.0	1.7
Xanomeline High Dose		Week 6	85.7	87.7	-2.0
Xanomeline High Dose		Week 6	79.0	86.0	-7.0
Xanomeline High Dose		Week 6	83.0	87.0	-4.0
Xanomeline High Dose		Week 8	90.0	87.7	2.3
Xanomeline High Dose		Week 8	81.7	86.0	-4.3
Xanomeline High Dose		Week 8	86.7	87.0	-0.3
Xanomeline High Dose			86.7	87.7
Xanomeline High Dose			86.7	86.0
Xanomeline High Dose			82.7	87.0
Xanomeline High Dose			88.3	87.7
Xanomeline High Dose			88.0	86.0
Xanomeline High Dose			82.7	87.0
Placebo		Week 2	89.7	99.0	-9.3
Placebo		Week 2	83.3	95.3	-12.0
Placebo		Week 2	83.7	94.0	-10.3
Placebo		Week 12	88.7	94.0	-5.3
Placebo		Week 12	90.3	93.3	-3.0
Placebo		Week 12	89.0	96.3	-7.3
Placebo		Week 16	95.0	94.0	1.0
Placebo		Week 16	94.0	93.3	0.7
Placebo		Week 16	99.3	96.3	3.0
Placebo		Week 2	89.7	94.0	-4.3
Placebo		Week 2	92.0	93.3	-1.3
Placebo		Week 2	90.7	96.3	-5.7
Placebo		Week 20	89.7	94.0	-4.3
Placebo		Week 20	94.0	93.3	0.7
Placebo		Week 20	91.3	96.3	-5.0
Placebo		Week 24	98.7	94.0	4.7
Placebo		Week 24	95.7	93.3	2.3
Placebo		Week 24	93.0	96.3	-3.3
Placebo		Week 26	96.3	94.0	2.3
Placebo		Week 26	93.7	93.3	0.3
Placebo		Week 26	92.3	96.3	-4.0
Placebo		Week 4	104.7	94.0	10.7
Placebo		Week 4	98.7	93.3	5.3
Placebo		Week 4	101.3	96.3	5.0
Placebo		Week 6	96.3	94.0	2.3
Placebo		Week 6	91.3	93.3	-2.0
Placebo		Week 6	97.3	96.3	1.0
Placebo		Week 8	91.0	94.0	-3.0
Placebo		Week 8	88.7	93.3	-4.7
Placebo		Week 8	88.7	96.3	-7.7
Placebo			88.3	94.0
Placebo			93.3	93.3
Placebo			91.0	96.3
Placebo			92.0	94.0
Placebo			96.0	93.3
Placebo			96.7	96.3
Placebo		Week 12	86.3	90.0	-3.7
Placebo		Week 12	83.3	88.7	-5.3
Placebo		Week 12	88.7	92.0	-3.3
Placebo		Week 16	82.0	90.0	-8.0
Placebo		Week 16	88.3	88.7	-0.3
Placebo		Week 16	81.3	92.0	-10.7
Placebo		Week 2	86.0	90.0	-4.0
Placebo		Week 2	86.0	88.7	-2.7
Placebo		Week 2	91.7	92.0	-0.3
Placebo		Week 20	87.7	90.0	-2.3
Placebo		Week 20	87.7	88.7	-1.0
Placebo		Week 20	94.0	92.0	2.0
Placebo		Week 24	79.0	90.0	-11.0
Placebo		Week 24	86.7	88.7	-2.0
Placebo		Week 24	83.7	92.0	-8.3
Placebo		Week 26	89.0	90.0	-1.0
Placebo		Week 26	79.7	88.7	-9.0
Placebo		Week 26	74.7	92.0	-17.3
Placebo		Week 4	81.7	90.0	-8.3
Placebo		Week 4	85.7	88.7	-3.0
Placebo		Week 4	91.7	92.0	-0.3
Placebo		Week 6	76.3	90.0	-13.7
Placebo		Week 6	74.7	88.7	-14.0
Placebo		Week 6	84.7	92.0	-7.3
Placebo		Week 8	93.0	90.0	3.0
Placebo		Week 8	84.7	88.7	-4.0
Placebo		Week 8	89.3	92.0	-2.7
Placebo			80.3	90.0
Placebo			78.3	88.7
Placebo			83.0	92.0
Placebo			87.7	90.0
Placebo			77.7	88.7
Placebo			87.0	92.0
Xanomeline Low Dose		Week 2	102.7	107.3	-4.7
Xanomeline Low Dose		Week 2	116.7	115.3	1.3
Xanomeline Low Dose		Week 2	112.0	110.7	1.3
Xanomeline Low Dose		Week 4	103.3	107.3	-4.0
Xanomeline Low Dose		Week 4	106.7	115.3	-8.7
Xanomeline Low Dose		Week 4	115.3	110.7	4.7
Xanomeline Low Dose		Week 6	105.3	107.3	-2.0
Xanomeline Low Dose		Week 6	111.3	115.3	-4.0
Xanomeline Low Dose		Week 6	106.7	110.7	-4.0
Placebo		Week 12	95.7	87.3	8.3
Placebo		Week 12	101.3	90.7	10.7
Placebo		Week 12	105.7	89.3	16.3
Placebo		Week 16	100.7	87.3	13.3
Placebo		Week 16	107.3	90.7	16.7
Placebo		Week 16	106.0	89.3	16.7
Placebo		Week 2	103.3	87.3	16.0
Placebo		Week 2	85.3	90.7	-5.3
Placebo		Week 2	84.7	89.3	-4.7
Placebo		Week 20	82.0	87.3	-5.3
Placebo		Week 20	91.3	90.7	0.7
Placebo		Week 20	92.3	89.3	3.0
Placebo		Week 24	95.7	87.3	8.3
Placebo		Week 24	100.7	90.7	10.0
Placebo		Week 24	104.0	89.3	14.7
Placebo		Week 26	80.0	87.3	-7.3
Placebo		Week 26	80.0	90.7	-10.7
Placebo		Week 26	78.0	89.3	-11.3
Placebo		Week 4	78.7	87.3	-8.7
Placebo		Week 4	77.0	90.7	-13.7
Placebo		Week 4	80.7	89.3	-8.7
Placebo		Week 6	76.7	87.3	-10.7
Placebo		Week 6	89.3	90.7	-1.3
Placebo		Week 6	81.7	89.3	-7.7
Placebo		Week 8	91.0	87.3	3.7
Placebo		Week 8	94.3	90.7	3.7
Placebo		Week 8	104.3	89.3	15.0
Placebo			84.0	87.3
Placebo			89.0	90.7
Placebo			87.0	89.3
Placebo			84.0	87.3
Placebo			89.0	90.7
Placebo			94.0	89.3
Xanomeline Low Dose		Week 12	92.3	92.3	0.0
Xanomeline Low Dose		Week 12	93.0	93.3	-0.3
Xanomeline Low Dose		Week 12	89.0	103.7	-14.7
Xanomeline Low Dose		Week 16	89.0	92.3	-3.3
Xanomeline Low Dose		Week 16	102.0	93.3	8.7
Xanomeline Low Dose		Week 16	95.0	103.7	-8.7
Xanomeline Low Dose		Week 2	105.7	92.3	13.3
Xanomeline Low Dose		Week 2	101.3	93.3	8.0
Xanomeline Low Dose		Week 2	93.7	103.7	-10.0
Xanomeline Low Dose		Week 20	100.3	92.3	8.0
Xanomeline Low Dose		Week 20	99.0	93.3	5.7
Xanomeline Low Dose		Week 20	93.0	103.7	-10.7
Xanomeline Low Dose		Week 24	91.3	92.3	-1.0
Xanomeline Low Dose		Week 24	89.0	93.3	-4.3
Xanomeline Low Dose		Week 24	103.0	103.7	-0.7
Xanomeline Low Dose		Week 26	103.0	92.3	10.7
Xanomeline Low Dose		Week 26	86.0	93.3	-7.3
Xanomeline Low Dose		Week 26	91.7	103.7	-12.0
Xanomeline Low Dose		Week 4	103.3	92.3	11.0
Xanomeline Low Dose		Week 4	91.0	93.3	-2.3
Xanomeline Low Dose		Week 4	96.3	103.7	-7.3
Xanomeline Low Dose		Week 6	94.0	92.3	1.7
Xanomeline Low Dose		Week 6	90.0	93.3	-3.3
Xanomeline Low Dose		Week 6	90.0	103.7	-13.7
Xanomeline Low Dose		Week 8	95.7	92.3	3.3
Xanomeline Low Dose		Week 8	96.3	93.3	3.0
Xanomeline Low Dose		Week 8	99.0	103.7	-4.7
Xanomeline Low Dose			96.7	92.3
Xanomeline Low Dose			95.7	93.3
Xanomeline Low Dose			93.0	103.7
Xanomeline Low Dose			105.3	92.3
Xanomeline Low Dose			96.7	93.3
Xanomeline Low Dose			103.3	103.7
Xanomeline High Dose		Week 2	104.7	112.3	-7.7
Xanomeline High Dose		Week 2	97.7	102.0	-4.3
Xanomeline High Dose		Week 2	101.0	96.7	4.3
Xanomeline High Dose		Week 4	104.0	112.3	-8.3
Xanomeline High Dose		Week 4	93.0	102.0	-9.0
Xanomeline High Dose		Week 4	101.7	96.7	5.0
Xanomeline High Dose			98.7	112.3
Xanomeline High Dose			83.0	102.0
Xanomeline High Dose			88.3	96.7
Xanomeline High Dose			92.7	112.3
Xanomeline High Dose			99.3	102.0
Xanomeline High Dose			97.7	96.7
Xanomeline Low Dose		Week 2	96.7	90.7	6.0
Xanomeline Low Dose		Week 2	83.3	80.3	3.0
Xanomeline Low Dose		Week 2	86.7	86.0	0.7
Xanomeline Low Dose		Week 4	98.7	90.7	8.0
Xanomeline Low Dose		Week 4	96.7	80.3	16.3
Xanomeline Low Dose		Week 4	99.0	86.0	13.0
Xanomeline Low Dose		Week 6	78.0	90.7	-12.7
Xanomeline Low Dose		Week 6	76.0	80.3	-4.3
Xanomeline Low Dose		Week 6	77.3	86.0	-8.7
Xanomeline Low Dose		Week 8	90.7	90.7	0.0
Xanomeline Low Dose		Week 8	87.3	80.3	7.0
Xanomeline Low Dose		Week 8	82.3	86.0	-3.7
Xanomeline Low Dose			96.0	90.7
Xanomeline Low Dose			88.7	80.3
Xanomeline Low Dose			80.0	86.0
Xanomeline Low Dose			72.0	90.7
Xanomeline Low Dose			67.3	80.3
Xanomeline Low Dose			63.3	86.0
Placebo		Week 12	91.3	80.7	10.7
Placebo		Week 12	90.7	80.0	10.7
Placebo		Week 12	88.7	82.0	6.7
Placebo		Week 16	80.0	80.7	-0.7
Placebo		Week 16	86.0	80.0	6.0
Placebo		Week 16	86.0	82.0	4.0
Placebo		Week 2	80.7	80.7	0.0
Placebo		Week 2	85.3	80.0	5.3
Placebo		Week 2	86.0	82.0	4.0
Placebo		Week 20	88.7	80.7	8.0
Placebo		Week 20	84.7	80.0	4.7
Placebo		Week 20	87.3	82.0	5.3
Placebo		Week 24	91.3	80.7	10.7
Placebo		Week 24	88.7	80.0	8.7
Placebo		Week 24	92.7	82.0	10.7
Placebo		Week 26	90.0	80.7	9.3
Placebo		Week 26	93.3	80.0	13.3
Placebo		Week 26	92.0	82.0	10.0
Placebo		Week 4	86.7	80.7	6.0
Placebo		Week 4	98.0	80.0	18.0
Placebo		Week 4	97.3	82.0	15.3
Placebo		Week 6	89.3	80.7	8.7
Placebo		Week 6	91.3	80.0	11.3
Placebo		Week 6	96.0	82.0	14.0
Placebo		Week 8	82.7	80.7	2.0
Placebo		Week 8	80.7	80.0	0.7
Placebo		Week 8	83.3	82.0	1.3
Placebo			87.3	80.7
Placebo			83.3	80.0
Placebo			87.3	82.0
Placebo			83.3	80.7
Placebo			85.3	80.0
Placebo			87.3	82.0
Xanomeline High Dose		Week 12	95.3	105.3	-10.0
Xanomeline High Dose		Week 12	91.3	105.3	-14.0
Xanomeline High Dose		Week 12	98.0	103.3	-5.3
Xanomeline High Dose		Week 2	110.0	105.3	4.7
Xanomeline High Dose		Week 2	105.0	105.3	-0.3
Xanomeline High Dose		Week 2	98.3	103.3	-5.0
Xanomeline High Dose		Week 4	100.0	105.3	-5.3
Xanomeline High Dose		Week 4	101.0	105.3	-4.3
Xanomeline High Dose		Week 4	96.7	103.3	-6.7
Xanomeline High Dose		Week 6	108.0	105.3	2.7
Xanomeline High Dose		Week 6	108.0	105.3	2.7
Xanomeline High Dose		Week 6	97.3	103.3	-6.0
Xanomeline High Dose		Week 8	113.3	105.3	8.0
Xanomeline High Dose		Week 8	106.7	105.3	1.3
Xanomeline High Dose		Week 8	109.3	103.3	6.0
Xanomeline High Dose			110.0	105.3
Xanomeline High Dose			105.0	105.3
Xanomeline High Dose			105.0	103.3
Xanomeline High Dose			110.0	105.3
Xanomeline High Dose			102.0	105.3
Xanomeline High Dose			103.3	103.3
Xanomeline Low Dose		Week 12	90.0	96.7	-6.7
Xanomeline Low Dose		Week 12	94.7	94.7	0.0
Xanomeline Low Dose		Week 12	96.7	91.3	5.3
Xanomeline Low Dose		Week 2	85.3	96.7	-11.3
Xanomeline Low Dose		Week 2	90.0	94.7	-4.7
Xanomeline Low Dose		Week 2	90.0	91.3	-1.3
Xanomeline Low Dose		Week 4	91.3	96.7	-5.3
Xanomeline Low Dose		Week 4	90.0	94.7	-4.7
Xanomeline Low Dose		Week 4	89.3	91.3	-2.0
Xanomeline Low Dose		Week 6	84.7	96.7	-12.0
Xanomeline Low Dose		Week 6	82.0	94.7	-12.7
Xanomeline Low Dose		Week 6	84.0	91.3	-7.3
Xanomeline Low Dose		Week 8	93.3	96.7	-3.3
Xanomeline Low Dose		Week 8	97.3	94.7	2.7
Xanomeline Low Dose		Week 8	97.3	91.3	6.0
Xanomeline Low Dose			81.3	96.7
Xanomeline Low Dose			86.7	94.7
Xanomeline Low Dose			84.7	91.3
Xanomeline Low Dose			84.7	96.7
Xanomeline Low Dose			90.0	94.7
Xanomeline Low Dose			90.7	91.3
Placebo		Week 2	96.0	94.0	2.0
Placebo		Week 2	103.3	98.0	5.3
Placebo		Week 2	100.7	94.7	6.0
Placebo		Week 4	103.3	94.0	9.3
Placebo		Week 4	100.0	98.0	2.0
Placebo		Week 4	101.3	94.7	6.7
Placebo			103.3	94.0
Placebo			101.3	98.0
Placebo			102.7	94.7
Placebo			100.0	94.0
Placebo			105.3	98.0
Placebo			102.0	94.7
Placebo		Week 12	90.0	100.7	-10.7
Placebo		Week 12	96.7	106.0	-9.3
Placebo		Week 12	96.7	110.7	-14.0
Placebo		Week 16	83.3	100.7	-17.3
Placebo		Week 16	91.3	106.0	-14.7
Placebo		Week 16	89.3	110.7	-21.3
Placebo		Week 2	98.7	100.7	-2.0
Placebo		Week 2	103.3	106.0	-2.7
Placebo		Week 2	104.0	110.7	-6.7
Placebo		Week 20	86.0	100.7	-14.7
Placebo		Week 20	90.0	106.0	-16.0
Placebo		Week 20	91.3	110.7	-19.3
Placebo		Week 24	92.7	100.7	-8.0
Placebo		Week 24	93.3	106.0	-12.7
Placebo		Week 24	92.0	110.7	-18.7
Placebo		Week 26	84.7	100.7	-16.0
Placebo		Week 26	88.0	106.0	-18.0
Placebo		Week 26	87.3	110.7	-23.3
Placebo		Week 4	90.7	100.7	-10.0
Placebo		Week 4	92.7	106.0	-13.3
Placebo		Week 4	93.3	110.7	-17.3
Placebo		Week 6	84.7	100.7	-16.0
Placebo		Week 6	85.3	106.0	-20.7
Placebo		Week 6	83.3	110.7	-27.3
Placebo		Week 8	96.7	100.7	-4.0
Placebo		Week 8	98.7	106.0	-7.3
Placebo		Week 8	96.0	110.7	-14.7
Placebo			94.7	100.7
Placebo			93.3	106.0
Placebo			97.3	110.7
Placebo			89.3	100.7
Placebo			92.0	106.0
Placebo			90.7	110.7
Xanomeline Low Dose		Week 12	95.3	96.0	-0.7
Xanomeline Low Dose		Week 12	92.7	93.3	-0.7
Xanomeline Low Dose		Week 12	92.7	90.7	2.0
Xanomeline Low Dose		Week 16	101.3	96.0	5.3
Xanomeline Low Dose		Week 16	90.0	93.3	-3.3
Xanomeline Low Dose		Week 16	93.3	90.7	2.7
Xanomeline Low Dose		Week 2	86.7	96.0	-9.3
Xanomeline Low Dose		Week 2	90.0	93.3	-3.3
Xanomeline Low Dose		Week 2	90.7	90.7	0.0
Xanomeline Low Dose		Week 4	86.7	96.0	-9.3
Xanomeline Low Dose		Week 4	91.3	93.3	-2.0
Xanomeline Low Dose		Week 4	87.3	90.7	-3.3
Xanomeline Low Dose		Week 6	92.7	96.0	-3.3
Xanomeline Low Dose		Week 6	93.3	93.3	0.0
Xanomeline Low Dose		Week 6	83.3	90.7	-7.3
Xanomeline Low Dose		Week 8	100.0	96.0	4.0
Xanomeline Low Dose		Week 8	96.0	93.3	2.7
Xanomeline Low Dose		Week 8	95.3	90.7	4.7
Xanomeline Low Dose			96.7	96.0
Xanomeline Low Dose			96.0	93.3
Xanomeline Low Dose			95.3	90.7
Xanomeline Low Dose			88.0	96.0
Xanomeline Low Dose			89.3	93.3
Xanomeline Low Dose			90.0	90.7
Xanomeline Low Dose		Week 2	90.0	100.0	-10.0
Xanomeline Low Dose		Week 2	93.3	103.3	-10.0
Xanomeline Low Dose		Week 2	89.3	88.0	1.3
Xanomeline Low Dose		Week 4	99.3	100.0	-0.7
Xanomeline Low Dose		Week 4	98.0	103.3	-5.3
Xanomeline Low Dose		Week 4	99.3	88.0	11.3
Xanomeline Low Dose		Week 6	95.3	100.0	-4.7
Xanomeline Low Dose		Week 6	84.7	103.3	-18.7
Xanomeline Low Dose		Week 6	81.3	88.0	-6.7
Xanomeline Low Dose			91.3	100.0
Xanomeline Low Dose			95.3	103.3
Xanomeline Low Dose			94.0	88.0
Placebo		Week 12	84.7	86.7	-2.0
Placebo		Week 12	82.0	98.0	-16.0
Placebo		Week 12	82.0	93.3	-11.3
Placebo		Week 16	78.7	86.7	-8.0
Placebo		Week 16	82.7	98.0	-15.3
Placebo		Week 16	84.7	93.3	-8.7
Placebo		Week 2	90.7	86.7	4.0
Placebo		Week 2	90.0	98.0	-8.0
Placebo		Week 2	89.3	93.3	-4.0
Placebo		Week 20	88.7	86.7	2.0
Placebo		Week 20	84.7	98.0	-13.3
Placebo		Week 20	84.0	93.3	-9.3
Placebo		Week 24	87.3	86.7	0.7
Placebo		Week 24	88.0	98.0	-10.0
Placebo		Week 24	86.0	93.3	-7.3
Placebo		Week 26	83.3	86.7	-3.3
Placebo		Week 26	84.0	98.0	-14.0
Placebo		Week 26	82.7	93.3	-10.7
Placebo		Week 4	90.0	86.7	3.3
Placebo		Week 4	88.7	98.0	-9.3
Placebo		Week 4	93.3	93.3	0.0
Placebo		Week 6	90.0	86.7	3.3
Placebo		Week 6	92.0	98.0	-6.0
Placebo		Week 6	90.0	93.3	-3.3
Placebo		Week 8	88.7	86.7	2.0
Placebo		Week 8	84.7	98.0	-13.3
Placebo		Week 8	84.0	93.3	-9.3
Placebo			88.7	86.7
Placebo			89.3	98.0
Placebo			93.3	93.3
Placebo			93.3	86.7
Placebo			92.0	98.0
Placebo			91.3	93.3
Xanomeline High Dose		Week 12	96.0	111.3	-15.3
Xanomeline High Dose		Week 12	95.3	114.0	-18.7
Xanomeline High Dose		Week 12	102.7	109.3	-6.7
Xanomeline High Dose		Week 16	111.3	111.3	0.0
Xanomeline High Dose		Week 16	108.0	114.0	-6.0
Xanomeline High Dose		Week 16	107.3	109.3	-2.0
Xanomeline High Dose		Week 2	104.0	111.3	-7.3
Xanomeline High Dose		Week 2	103.3	114.0	-10.7
Xanomeline High Dose		Week 2	105.3	109.3	-4.0
Xanomeline High Dose		Week 20	100.0	111.3	-11.3
Xanomeline High Dose		Week 20	102.7	114.0	-11.3
Xanomeline High Dose		Week 20	104.7	109.3	-4.7
Xanomeline High Dose		Week 24	92.7	111.3	-18.7
Xanomeline High Dose		Week 24	93.3	114.0	-20.7
Xanomeline High Dose		Week 24	93.3	109.3	-16.0
Xanomeline High Dose		Week 4	96.7	111.3	-14.7
Xanomeline High Dose		Week 4	93.3	114.0	-20.7
Xanomeline High Dose		Week 4	96.0	109.3	-13.3
Xanomeline High Dose		Week 6	96.7	111.3	-14.7
Xanomeline High Dose		Week 6	98.7	114.0	-15.3
Xanomeline High Dose		Week 6	100.0	109.3	-9.3
Xanomeline High Dose		Week 8	90.0	111.3	-21.3
Xanomeline High Dose		Week 8	92.0	114.0	-22.0
Xanomeline High Dose		Week 8	96.7	109.3	-12.7
Xanomeline High Dose			98.0	111.3
Xanomeline High Dose			101.3	114.0
Xanomeline High Dose			98.0	109.3
Xanomeline High Dose			96.7	111.3
Xanomeline High Dose			92.7	114.0
Xanomeline High Dose			96.0	109.3
Xanomeline High Dose		Week 12	100.0	98.0	2.0
Xanomeline High Dose		Week 12	96.7	100.7	-4.0
Xanomeline High Dose		Week 12	96.0	97.3	-1.3
Xanomeline High Dose		Week 16	100.0	98.0	2.0
Xanomeline High Dose		Week 16	100.7	100.7	0.0
Xanomeline High Dose		Week 16	103.3	97.3	6.0
Xanomeline High Dose		Week 2	90.0	98.0	-8.0
Xanomeline High Dose		Week 2	78.0	100.7	-22.7
Xanomeline High Dose		Week 2	74.7	97.3	-22.7
Xanomeline High Dose		Week 4	98.7	98.0	0.7
Xanomeline High Dose		Week 4	87.3	100.7	-13.3
Xanomeline High Dose		Week 4	108.0	97.3	10.7
Xanomeline High Dose		Week 6	104.7	98.0	6.7
Xanomeline High Dose		Week 6	92.7	100.7	-8.0
Xanomeline High Dose		Week 6	91.3	97.3	-6.0
Xanomeline High Dose		Week 8	96.7	98.0	-1.3
Xanomeline High Dose		Week 8	94.7	100.7	-6.0
Xanomeline High Dose		Week 8	94.0	97.3	-3.3
Xanomeline High Dose			96.0	98.0
Xanomeline High Dose			98.7	100.7
Xanomeline High Dose			98.0	97.3
Xanomeline High Dose			99.3	98.0
Xanomeline High Dose			91.3	100.7
Xanomeline High Dose			97.3	97.3
Placebo		Week 12	83.3	82.7	0.7
Placebo		Week 12	89.3	77.3	12.0
Placebo		Week 12	90.7	80.7	10.0
Placebo		Week 16	88.7	82.7	6.0
Placebo		Week 16	89.3	77.3	12.0
Placebo		Week 16	89.3	80.7	8.7
Placebo		Week 2	77.3	82.7	-5.3
Placebo		Week 2	77.3	77.3	0.0
Placebo		Week 2	80.7	80.7	0.0
Placebo		Week 20	80.0	82.7	-2.7
Placebo		Week 20	80.7	77.3	3.3
Placebo		Week 20	79.3	80.7	-1.3
Placebo		Week 24	80.0	82.7	-2.7
Placebo		Week 24	78.7	77.3	1.3
Placebo		Week 24	77.3	80.7	-3.3
Placebo		Week 26	68.0	82.7	-14.7
Placebo		Week 26	66.7	77.3	-10.7
Placebo		Week 26	73.3	80.7	-7.3
Placebo		Week 4	78.7	82.7	-4.0
Placebo		Week 4	79.3	77.3	2.0
Placebo		Week 4	77.3	80.7	-3.3
Placebo		Week 6	80.7	82.7	-2.0
Placebo		Week 6	76.7	77.3	-0.7
Placebo		Week 6	73.3	80.7	-7.3
Placebo		Week 8	85.3	82.7	2.7
Placebo		Week 8	83.3	77.3	6.0
Placebo		Week 8	73.3	80.7	-7.3
Placebo			80.7	82.7
Placebo			80.7	77.3
Placebo			84.0	80.7
Placebo			84.7	82.7
Placebo			82.0	77.3
Placebo			82.7	80.7
Xanomeline High Dose		Week 2	100.0	96.7	3.3
Xanomeline High Dose		Week 2	101.3	93.3	8.0
Xanomeline High Dose		Week 2	98.7	96.7	2.0
Xanomeline High Dose		Week 4	93.3	96.7	-3.3
Xanomeline High Dose		Week 4	90.0	93.3	-3.3
Xanomeline High Dose		Week 4	86.7	96.7	-10.0
Xanomeline High Dose			73.3	96.7
Xanomeline High Dose			75.3	93.3
Xanomeline High Dose			73.3	96.7
Xanomeline High Dose			88.0	96.7
Xanomeline High Dose			92.7	93.3
Xanomeline High Dose			86.0	96.7
Xanomeline Low Dose		Week 12	96.7	100.0	-3.3
Xanomeline Low Dose		Week 12	104.7	103.3	1.3
Xanomeline Low Dose		Week 12	99.3	107.3	-8.0
Xanomeline Low Dose		Week 16	90.0	100.0	-10.0
Xanomeline Low Dose		Week 16	97.3	103.3	-6.0
Xanomeline Low Dose		Week 16	96.7	107.3	-10.7
Xanomeline Low Dose		Week 2	84.7	100.0	-15.3
Xanomeline Low Dose		Week 2	96.0	103.3	-7.3
Xanomeline Low Dose		Week 2	95.3	107.3	-12.0
Xanomeline Low Dose		Week 20	97.3	100.0	-2.7
Xanomeline Low Dose		Week 20	104.7	103.3	1.3
Xanomeline Low Dose		Week 20	97.3	107.3	-10.0
Xanomeline Low Dose		Week 24	99.3	100.0	-0.7
Xanomeline Low Dose		Week 24	104.0	103.3	0.7
Xanomeline Low Dose		Week 24	100.7	107.3	-6.7
Xanomeline Low Dose		Week 26	94.0	100.0	-6.0
Xanomeline Low Dose		Week 26	95.3	103.3	-8.0
Xanomeline Low Dose		Week 26	98.0	107.3	-9.3
Xanomeline Low Dose		Week 4	90.0	100.0	-10.0
Xanomeline Low Dose		Week 4	98.0	103.3	-5.3
Xanomeline Low Dose		Week 4	91.3	107.3	-16.0
Xanomeline Low Dose		Week 6	97.3	100.0	-2.7
Xanomeline Low Dose		Week 6	108.7	103.3	5.3
Xanomeline Low Dose		Week 6	100.0	107.3	-7.3
Xanomeline Low Dose		Week 8	100.0	100.0	0.0
Xanomeline Low Dose		Week 8	104.0	103.3	0.7
Xanomeline Low Dose		Week 8	108.0	107.3	0.7
Xanomeline Low Dose			93.3	100.0
Xanomeline Low Dose			106.0	103.3
Xanomeline Low Dose			100.0	107.3
Xanomeline Low Dose			89.3	100.0
Xanomeline Low Dose			87.3	103.3
Xanomeline Low Dose			92.0	107.3
Xanomeline High Dose		Week 12	101.3	104.7	-3.3
Xanomeline High Dose		Week 12	100.7	112.7	-12.0
Xanomeline High Dose		Week 12	100.7	113.3	-12.7
Xanomeline High Dose		Week 16	101.3	104.7	-3.3
Xanomeline High Dose		Week 16	105.3	112.7	-7.3
Xanomeline High Dose		Week 16	103.3	113.3	-10.0
Xanomeline High Dose		Week 2	108.0	104.7	3.3
Xanomeline High Dose		Week 2	111.3	112.7	-1.3
Xanomeline High Dose		Week 2	108.3	113.3	-5.0
Xanomeline High Dose		Week 20	103.3	104.7	-1.3
Xanomeline High Dose		Week 20	102.0	112.7	-10.7
Xanomeline High Dose		Week 20	103.3	113.3	-10.0
Xanomeline High Dose		Week 24	92.7	104.7	-12.0
Xanomeline High Dose		Week 24	96.7	112.7	-16.0
Xanomeline High Dose		Week 24	94.7	113.3	-18.7
Xanomeline High Dose		Week 26	97.3	104.7	-7.3
Xanomeline High Dose		Week 26	99.3	112.7	-13.3
Xanomeline High Dose		Week 26	100.0	113.3	-13.3
Xanomeline High Dose		Week 4	106.7	104.7	2.0
Xanomeline High Dose		Week 4	109.0	112.7	-3.7
Xanomeline High Dose		Week 4	107.3	113.3	-6.0
Xanomeline High Dose		Week 6	92.7	104.7	-12.0
Xanomeline High Dose		Week 6	92.7	112.7	-20.0
Xanomeline High Dose		Week 6	90.7	113.3	-22.7
Xanomeline High Dose		Week 8	92.0	104.7	-12.7
Xanomeline High Dose		Week 8	93.3	112.7	-19.3
Xanomeline High Dose		Week 8	94.0	113.3	-19.3
Xanomeline High Dose			107.3	104.7
Xanomeline High Dose			111.3	112.7
Xanomeline High Dose			113.3	113.3
Xanomeline High Dose			101.3	104.7
Xanomeline High Dose			103.3	112.7
Xanomeline High Dose			99.3	113.3
Xanomeline High Dose		Week 2	97.3	103.3	-6.0
Xanomeline High Dose		Week 4	90.7	103.3	-12.7
Xanomeline High Dose		Week 4	102.0	104.7	-2.7
Xanomeline High Dose		Week 4	98.0	99.3	-1.3
Xanomeline High Dose			100.7	103.3
Xanomeline High Dose			104.0	104.7
Xanomeline High Dose			96.0	99.3
Xanomeline High Dose			98.0	103.3
Xanomeline High Dose			98.7	104.7
Xanomeline High Dose			97.3	99.3
Xanomeline Low Dose		Week 2	83.3	99.3	-16.0
Xanomeline Low Dose		Week 2	87.3	96.0	-8.7
Xanomeline Low Dose		Week 2	90.7	100.0	-9.3
Xanomeline Low Dose			89.3	99.3
Xanomeline Low Dose			96.0	96.0
Xanomeline Low Dose			106.7	100.0
Placebo		Week 12	101.3	115.3	-14.0
Placebo		Week 12	92.7	118.0	-25.3
Placebo		Week 12	93.3	116.0	-22.7
Placebo		Week 16	106.7	115.3	-8.7
Placebo		Week 16	95.3	118.0	-22.7
Placebo		Week 16	92.7	116.0	-23.3
Placebo		Week 2	99.3	115.3	-16.0
Placebo		Week 2	114.7	118.0	-3.3
Placebo		Week 2	108.7	116.0	-7.3
Placebo		Week 4	106.0	115.3	-9.3
Placebo		Week 4	110.7	118.0	-7.3
Placebo		Week 4	106.7	116.0	-9.3
Placebo		Week 6	113.3	115.3	-2.0
Placebo		Week 6	106.7	118.0	-11.3
Placebo		Week 6	110.0	116.0	-6.0
Placebo		Week 8	116.0	115.3	0.7
Placebo		Week 8	112.0	118.0	-6.0
Placebo		Week 8	108.0	116.0	-8.0
Placebo			93.3	115.3
Placebo			99.3	118.0
Placebo			100.7	116.0
Placebo			109.3	115.3
Placebo			108.0	118.0
Placebo			112.7	116.0
Xanomeline High Dose		Week 2	77.3	94.7	-17.3
Xanomeline High Dose		Week 2	74.0	84.0	-10.0
Xanomeline High Dose		Week 2	72.0	88.7	-16.7
Xanomeline High Dose		Week 4	85.3	94.7	-9.3
Xanomeline High Dose		Week 4	76.7	84.0	-7.3
Xanomeline High Dose		Week 4	75.3	88.7	-13.3
Xanomeline High Dose			87.3	94.7
Xanomeline High Dose			80.7	84.0
Xanomeline High Dose			85.3	88.7
Xanomeline Low Dose		Week 2	96.0	104.7	-8.7
Xanomeline Low Dose		Week 2	110.7	97.3	13.3
Xanomeline Low Dose		Week 2	106.7	104.7	2.0
Xanomeline Low Dose			102.7	104.7
Xanomeline Low Dose			108.7	97.3
Xanomeline Low Dose			114.7	104.7
Xanomeline High Dose		Week 2	104.7	104.7	0.0
Xanomeline High Dose		Week 2	106.7	108.7	-2.0
Xanomeline High Dose		Week 2	104.0	110.7	-6.7
Xanomeline High Dose		Week 4	98.7	104.7	-6.0
Xanomeline High Dose		Week 4	101.3	108.7	-7.3
Xanomeline High Dose		Week 4	105.3	110.7	-5.3
Xanomeline High Dose		Week 6	94.0	104.7	-10.7
Xanomeline High Dose		Week 6	89.3	108.7	-19.3
Xanomeline High Dose		Week 6	88.7	110.7	-22.0
Xanomeline High Dose		Week 8	100.7	104.7	-4.0
Xanomeline High Dose		Week 8	92.0	108.7	-16.7
Xanomeline High Dose		Week 8	88.0	110.7	-22.7
Xanomeline High Dose			90.0	104.7
Xanomeline High Dose			96.0	108.7
Xanomeline High Dose			98.0	110.7
Xanomeline High Dose			86.7	104.7
Xanomeline High Dose			92.0	108.7
Xanomeline High Dose			90.7	110.7
Xanomeline High Dose		Week 2	110.7	110.0	0.7
Xanomeline High Dose		Week 2	106.7	106.7	0.0
Xanomeline High Dose		Week 2	108.0	112.7	-4.7
Xanomeline High Dose		Week 4	110.0	110.0	0.0
Xanomeline High Dose		Week 4	107.3	106.7	0.7
Xanomeline High Dose		Week 4	108.7	112.7	-4.0
Xanomeline High Dose		Week 6	109.3	110.0	-0.7
Xanomeline High Dose		Week 6	102.0	106.7	-4.7
Xanomeline High Dose		Week 6	106.0	112.7	-6.7
Xanomeline High Dose			116.7	110.0
Xanomeline High Dose			108.7	106.7
Xanomeline High Dose			112.0	112.7
Xanomeline High Dose			108.7	110.0
Xanomeline High Dose			107.3	106.7
Xanomeline High Dose			110.7	112.7
Xanomeline High Dose		Week 12	99.3	109.3	-10.0
Xanomeline High Dose		Week 12	110.7	110.7	0.0
Xanomeline High Dose		Week 12	100.0	106.7	-6.7
Xanomeline High Dose		Week 2	104.0	109.3	-5.3
Xanomeline High Dose		Week 2	106.0	110.7	-4.7
Xanomeline High Dose		Week 2	104.7	106.7	-2.0
Xanomeline High Dose		Week 4	108.7	109.3	-0.7
Xanomeline High Dose		Week 4	112.0	110.7	1.3
Xanomeline High Dose		Week 4	101.3	106.7	-5.3
Xanomeline High Dose		Week 6	108.0	109.3	-1.3
Xanomeline High Dose		Week 6	100.0	110.7	-10.7
Xanomeline High Dose		Week 6	98.7	106.7	-8.0
Xanomeline High Dose		Week 8	107.3	109.3	-2.0
Xanomeline High Dose		Week 8	109.3	110.7	-1.3
Xanomeline High Dose		Week 8	108.0	106.7	1.3
Xanomeline High Dose			102.0	109.3
Xanomeline High Dose			107.3	110.7
Xanomeline High Dose			104.7	106.7
Xanomeline High Dose			106.7	109.3
Xanomeline High Dose			112.7	110.7
Xanomeline High Dose			109.3	106.7
Xanomeline Low Dose		Week 12	107.3	98.7	8.7
Xanomeline Low Dose		Week 12	93.3	90.7	2.7
Xanomeline Low Dose		Week 12	96.0	91.3	4.7
Xanomeline Low Dose		Week 16	106.0	98.7	7.3
Xanomeline Low Dose		Week 16	106.0	90.7	15.3
Xanomeline Low Dose		Week 16	106.7	91.3	15.3
Xanomeline Low Dose		Week 2	99.3	98.7	0.7
Xanomeline Low Dose		Week 2	92.7	90.7	2.0
Xanomeline Low Dose		Week 2	98.7	91.3	7.3
Xanomeline Low Dose		Week 20	106.7	98.7	8.0
Xanomeline Low Dose		Week 20	106.0	90.7	15.3
Xanomeline Low Dose		Week 20	106.0	91.3	14.7
Xanomeline Low Dose		Week 4	94.7	98.7	-4.0
Xanomeline Low Dose		Week 4	91.3	90.7	0.7
Xanomeline Low Dose		Week 4	97.3	91.3	6.0
Xanomeline Low Dose		Week 6	86.7	98.7	-12.0
Xanomeline Low Dose		Week 6	94.7	90.7	4.0
Xanomeline Low Dose		Week 6	95.3	91.3	4.0
Xanomeline Low Dose		Week 8	90.0	98.7	-8.7
Xanomeline Low Dose		Week 8	94.7	90.7	4.0
Xanomeline Low Dose		Week 8	92.0	91.3	0.7
Xanomeline Low Dose			103.3	98.7
Xanomeline Low Dose			102.7	90.7
Xanomeline Low Dose			99.3	91.3
Xanomeline Low Dose			96.0	98.7
Xanomeline Low Dose			91.3	90.7
Xanomeline Low Dose			88.7	91.3
Xanomeline Low Dose		Week 2	103.3	94.7	8.7
Xanomeline Low Dose		Week 2	94.0	96.0	-2.0
Xanomeline Low Dose		Week 2	98.0	93.3	4.7
Xanomeline Low Dose		Week 4	102.7	94.7	8.0
Xanomeline Low Dose		Week 4	99.3	96.0	3.3
Xanomeline Low Dose		Week 4	104.7	93.3	11.3
Xanomeline Low Dose		Week 6	95.3	94.7	0.7
Xanomeline Low Dose		Week 6	98.7	96.0	2.7
Xanomeline Low Dose		Week 6	98.0	93.3	4.7
Xanomeline Low Dose		Week 8	94.7	94.7	0.0
Xanomeline Low Dose		Week 8	101.3	96.0	5.3
Xanomeline Low Dose		Week 8	92.0	93.3	-1.3
Xanomeline Low Dose			100.0	94.7
Xanomeline Low Dose			94.0	96.0
Xanomeline Low Dose			92.7	93.3
Xanomeline Low Dose			94.0	94.7
Xanomeline Low Dose			99.3	96.0
Xanomeline Low Dose			101.3	93.3
Placebo		Week 12	84.0	81.3	2.7
Placebo		Week 12	76.0	93.3	-17.3
Placebo		Week 12	76.0	88.0	-12.0
Placebo		Week 16	84.0	81.3	2.7
Placebo		Week 16	78.0	93.3	-15.3
Placebo		Week 16	77.3	88.0	-10.7
Placebo		Week 2	86.0	81.3	4.7
Placebo		Week 2	84.7	93.3	-8.7
Placebo		Week 2	88.0	88.0	0.0
Placebo		Week 20	88.7	81.3	7.3
Placebo		Week 20	80.0	93.3	-13.3
Placebo		Week 20	79.3	88.0	-8.7
Placebo		Week 24	84.7	81.3	3.3
Placebo		Week 24	84.7	93.3	-8.7
Placebo		Week 24	86.7	88.0	-1.3
Placebo		Week 26	82.0	81.3	0.7
Placebo		Week 26	82.7	93.3	-10.7
Placebo		Week 26	86.0	88.0	-2.0
Placebo		Week 4	82.0	81.3	0.7
Placebo		Week 4	75.3	93.3	-18.0
Placebo		Week 4	79.3	88.0	-8.7
Placebo		Week 6	90.0	81.3	8.7
Placebo		Week 6	86.7	93.3	-6.7
Placebo		Week 6	84.0	88.0	-4.0
Placebo		Week 8	78.0	81.3	-3.3
Placebo		Week 8	85.3	93.3	-8.0
Placebo		Week 8	82.7	88.0	-5.3
Placebo			79.3	81.3
Placebo			86.0	93.3
Placebo			86.0	88.0
Placebo			81.3	81.3
Placebo			74.7	93.3
Placebo			72.7	88.0
Xanomeline Low Dose		Week 12	88.0	97.3	-9.3
Xanomeline Low Dose		Week 12	79.3	90.0	-10.7
Xanomeline Low Dose		Week 12	82.7	95.3	-12.7
Xanomeline Low Dose		Week 16	88.7	97.3	-8.7
Xanomeline Low Dose		Week 16	88.7	90.0	-1.3
Xanomeline Low Dose		Week 16	92.0	95.3	-3.3
Xanomeline Low Dose		Week 2	96.0	97.3	-1.3
Xanomeline Low Dose		Week 2	96.7	90.0	6.7
Xanomeline Low Dose		Week 2	90.7	95.3	-4.7
Xanomeline Low Dose		Week 20	89.3	97.3	-8.0
Xanomeline Low Dose		Week 20	88.0	90.0	-2.0
Xanomeline Low Dose		Week 20	90.7	95.3	-4.7
Xanomeline Low Dose		Week 24	94.0	97.3	-3.3
Xanomeline Low Dose		Week 24	96.7	90.0	6.7
Xanomeline Low Dose		Week 24	92.0	95.3	-3.3
Xanomeline Low Dose		Week 26	88.7	97.3	-8.7
Xanomeline Low Dose		Week 26	91.3	90.0	1.3
Xanomeline Low Dose		Week 26	86.7	95.3	-8.7
Xanomeline Low Dose		Week 4	100.7	97.3	3.3
Xanomeline Low Dose		Week 4	98.7	90.0	8.7
Xanomeline Low Dose		Week 4	93.3	95.3	-2.0
Xanomeline Low Dose		Week 6	96.0	97.3	-1.3
Xanomeline Low Dose		Week 6	96.0	90.0	6.0
Xanomeline Low Dose		Week 6	97.3	95.3	2.0
Xanomeline Low Dose		Week 8	93.3	97.3	-4.0
Xanomeline Low Dose		Week 8	92.0	90.0	2.0
Xanomeline Low Dose		Week 8	95.3	95.3	0.0
Xanomeline Low Dose			96.7	97.3
Xanomeline Low Dose			97.3	90.0
Xanomeline Low Dose			95.3	95.3
Xanomeline Low Dose			92.7	97.3
Xanomeline Low Dose			98.0	90.0
Xanomeline Low Dose			98.0	95.3
Placebo		Week 12	84.7	81.3	3.3
Placebo		Week 12	84.7	92.0	-7.3
Placebo		Week 12	85.3	90.0	-4.7
Placebo		Week 16	83.3	81.3	2.0
Placebo		Week 16	84.7	92.0	-7.3
Placebo		Week 16	83.3	90.0	-6.7
Placebo		Week 2	83.3	81.3	2.0
Placebo		Week 2	78.7	92.0	-13.3
Placebo		Week 2	81.3	90.0	-8.7
Placebo		Week 20	90.0	81.3	8.7
Placebo		Week 20	89.3	92.0	-2.7
Placebo		Week 20	91.3	90.0	1.3
Placebo		Week 24	88.7	81.3	7.3
Placebo		Week 24	74.0	92.0	-18.0
Placebo		Week 24	80.0	90.0	-10.0
Placebo		Week 26	70.0	81.3	-11.3
Placebo		Week 26	68.0	92.0	-24.0
Placebo		Week 26	66.7	90.0	-23.3
Placebo		Week 4	78.7	81.3	-2.7
Placebo		Week 4	82.0	92.0	-10.0
Placebo		Week 4	83.3	90.0	-6.7
Placebo		Week 6	84.7	81.3	3.3
Placebo		Week 6	84.7	92.0	-7.3
Placebo		Week 6	87.3	90.0	-2.7
Placebo		Week 8	85.3	81.3	4.0
Placebo		Week 8	86.0	92.0	-6.0
Placebo		Week 8	84.0	90.0	-6.0
Placebo			86.0	81.3
Placebo			80.0	92.0
Placebo			84.7	90.0
Placebo			83.3	81.3
Placebo			82.0	92.0
Placebo			86.7	90.0
Xanomeline Low Dose		Week 12	110.0	100.7	9.3
Xanomeline Low Dose		Week 12	108.7	106.0	2.7
Xanomeline Low Dose		Week 12	104.7	100.7	4.0
Xanomeline Low Dose		Week 16	107.3	100.7	6.7
Xanomeline Low Dose		Week 16	108.0	106.0	2.0
Xanomeline Low Dose		Week 16	109.3	100.7	8.7
Xanomeline Low Dose		Week 2	104.0	100.7	3.3
Xanomeline Low Dose		Week 2	110.7	106.0	4.7
Xanomeline Low Dose		Week 2	111.3	100.7	10.7
Xanomeline Low Dose		Week 20	106.0	100.7	5.3
Xanomeline Low Dose		Week 20	109.3	106.0	3.3
Xanomeline Low Dose		Week 20	105.3	100.7	4.7
Xanomeline Low Dose		Week 24	106.0	100.7	5.3
Xanomeline Low Dose		Week 24	109.3	106.0	3.3
Xanomeline Low Dose		Week 24	108.0	100.7	7.3
Xanomeline Low Dose		Week 26	116.7	100.7	16.0
Xanomeline Low Dose		Week 26	108.7	106.0	2.7
Xanomeline Low Dose		Week 26	108.0	100.7	7.3
Xanomeline Low Dose		Week 4	105.3	100.7	4.7
Xanomeline Low Dose		Week 4	112.0	106.0	6.0
Xanomeline Low Dose		Week 4	108.0	100.7	7.3
Xanomeline Low Dose		Week 6	110.0	100.7	9.3
Xanomeline Low Dose		Week 6	110.0	106.0	4.0
Xanomeline Low Dose		Week 6	109.3	100.7	8.7
Xanomeline Low Dose		Week 8	106.0	100.7	5.3
Xanomeline Low Dose		Week 8	103.3	106.0	-2.7
Xanomeline Low Dose		Week 8	104.7	100.7	4.0
Xanomeline Low Dose			104.0	100.7
Xanomeline Low Dose			107.3	106.0
Xanomeline Low Dose			109.3	100.7
Xanomeline Low Dose			106.0	100.7
Xanomeline Low Dose			110.7	106.0
Xanomeline Low Dose			107.3	100.7
Placebo		Week 2	104.7	103.3	1.3
Placebo		Week 2	98.7	106.0	-7.3
Placebo		Week 2	95.3	100.7	-5.3
Placebo			106.7	103.3
Placebo			103.3	106.0
Placebo			106.7	100.7
Xanomeline High Dose		Week 2	91.3	86.0	5.3
Xanomeline High Dose		Week 2	94.7	83.3	11.3
Xanomeline High Dose		Week 2	93.3	84.7	8.7
Xanomeline High Dose		Week 4	103.3	86.0	17.3
Xanomeline High Dose		Week 4	99.3	83.3	16.0
Xanomeline High Dose		Week 4	98.7	84.7	14.0
Xanomeline High Dose		Week 6	98.7	86.0	12.7
Xanomeline High Dose		Week 6	96.7	83.3	13.3
Xanomeline High Dose		Week 6	100.0	84.7	15.3
Xanomeline High Dose			93.3	86.0
Xanomeline High Dose			88.7	83.3
Xanomeline High Dose			88.7	84.7
Xanomeline High Dose			102.0	86.0
Xanomeline High Dose			101.3	83.3
Xanomeline High Dose			100.0	84.7
Placebo		Week 2	89.3	102.7	-13.3
Placebo		Week 2	89.3	93.3	-4.0
Placebo		Week 2	91.3	88.7	2.7
Placebo		Week 4	93.3	102.7	-9.3
Placebo		Week 4	87.3	93.3	-6.0
Placebo		Week 4	90.7	88.7	2.0
Placebo		Week 6	104.0	102.7	1.3
Placebo		Week 6	89.3	93.3	-4.0
Placebo		Week 6	88.0	88.7	-0.7
Placebo		Week 8	106.0	102.7	3.3
Placebo		Week 8	90.7	93.3	-2.7
Placebo		Week 8	89.3	88.7	0.7
Placebo			101.3	102.7
Placebo			96.0	93.3
Placebo			95.3	88.7
Placebo			92.7	102.7
Placebo			82.7	93.3
Placebo			83.3	88.7
Xanomeline High Dose		Week 2	92.7	88.0	4.7
Xanomeline High Dose		Week 2	86.0	83.3	2.7
Xanomeline High Dose		Week 2	87.3	88.0	-0.7
Xanomeline High Dose		Week 4	89.3	88.0	1.3
Xanomeline High Dose		Week 4	88.0	83.3	4.7
Xanomeline High Dose		Week 4	90.0	88.0	2.0
Xanomeline High Dose		Week 6	86.7	88.0	-1.3
Xanomeline High Dose		Week 6	94.7	83.3	11.3
Xanomeline High Dose		Week 6	92.0	88.0	4.0
Xanomeline High Dose		Week 8	99.3	88.0	11.3
Xanomeline High Dose		Week 8	99.3	83.3	16.0
Xanomeline High Dose		Week 8	94.0	88.0	6.0
Xanomeline High Dose			87.3	88.0
Xanomeline High Dose			90.0	83.3
Xanomeline High Dose			86.0	88.0
Xanomeline High Dose			92.0	88.0
Xanomeline High Dose			86.7	83.3
Xanomeline High Dose			92.7	88.0
Xanomeline Low Dose		Week 2	93.3	96.0	-2.7
Xanomeline Low Dose		Week 2	100.0	102.7	-2.7
Xanomeline Low Dose		Week 2	100.7	98.0	2.7
Xanomeline Low Dose		Week 4	89.3	96.0	-6.7
Xanomeline Low Dose		Week 4	84.0	102.7	-18.7
Xanomeline Low Dose		Week 4	94.0	98.0	-4.0
Xanomeline Low Dose			100.7	96.0
Xanomeline Low Dose			102.0	102.7
Xanomeline Low Dose			102.7	98.0
Xanomeline Low Dose		Week 2	76.0	76.7	-0.7
Xanomeline Low Dose		Week 2	86.0	94.7	-8.7
Xanomeline Low Dose		Week 2	87.3	97.3	-10.0
Xanomeline Low Dose		Week 4	79.3	76.7	2.7
Xanomeline Low Dose		Week 4	86.7	94.7	-8.0
Xanomeline Low Dose		Week 4	88.0	97.3	-9.3
Xanomeline Low Dose		Week 6	86.0	76.7	9.3
Xanomeline Low Dose		Week 6	88.7	94.7	-6.0
Xanomeline Low Dose		Week 6	88.0	97.3	-9.3
Xanomeline Low Dose		Week 8	88.0	76.7	11.3
Xanomeline Low Dose		Week 8	90.7	94.7	-4.0
Xanomeline Low Dose		Week 8	90.7	97.3	-6.7
Xanomeline Low Dose			82.7	76.7
Xanomeline Low Dose			94.0	94.7
Xanomeline Low Dose			100.7	97.3
Xanomeline Low Dose			83.3	76.7
Xanomeline Low Dose			85.3	94.7
Xanomeline Low Dose			86.0	97.3
Xanomeline High Dose		Week 2	96.7	100.0	-3.3
Xanomeline High Dose		Week 2	98.7	104.0	-5.3
Xanomeline High Dose		Week 2	94.0	107.3	-13.3
Xanomeline High Dose		Week 4	88.0	100.0	-12.0
Xanomeline High Dose		Week 4	102.7	104.0	-1.3
Xanomeline High Dose		Week 4	101.3	107.3	-6.0
Xanomeline High Dose		Week 6	96.0	100.0	-4.0
Xanomeline High Dose		Week 6	99.3	104.0	-4.7
Xanomeline High Dose		Week 6	100.7	107.3	-6.7
Xanomeline High Dose		Week 8	97.3	100.0	-2.7
Xanomeline High Dose		Week 8	94.7	104.0	-9.3
Xanomeline High Dose		Week 8	93.3	107.3	-14.0
Xanomeline High Dose			99.3	100.0
Xanomeline High Dose			100.7	104.0
Xanomeline High Dose			98.7	107.3
Xanomeline High Dose			87.3	100.0
Xanomeline High Dose			92.0	104.0
Xanomeline High Dose			94.7	107.3
Placebo		Week 12	90.0	94.7	-4.7
Placebo		Week 12	100.7	98.7	2.0
Placebo		Week 12	97.3	97.3	0.0
Placebo		Week 16	91.3	94.7	-3.3
Placebo		Week 16	104.0	98.7	5.3
Placebo		Week 16	82.7	97.3	-14.7
Placebo		Week 2	94.7	94.7	0.0
Placebo		Week 2	102.7	98.7	4.0
Placebo		Week 2	98.0	97.3	0.7
Placebo		Week 20	91.3	94.7	-3.3
Placebo		Week 20	104.0	98.7	5.3
Placebo		Week 20	91.3	97.3	-6.0
Placebo		Week 24	88.0	94.7	-6.7
Placebo		Week 24	98.7	98.7	0.0
Placebo		Week 24	85.3	97.3	-12.0
Placebo		Week 26	93.3	94.7	-1.3
Placebo		Week 26	94.0	98.7	-4.7
Placebo		Week 26	92.7	97.3	-4.7
Placebo		Week 4	92.7	94.7	-2.0
Placebo		Week 4	92.7	98.7	-6.0
Placebo		Week 4	87.3	97.3	-10.0
Placebo		Week 6	88.7	94.7	-6.0
Placebo		Week 6	84.7	98.7	-14.0
Placebo		Week 6	88.0	97.3	-9.3
Placebo		Week 8	94.0	94.7	-0.7
Placebo		Week 8	96.0	98.7	-2.7
Placebo		Week 8	98.0	97.3	0.7
Placebo			94.7	94.7
Placebo			96.7	98.7
Placebo			92.7	97.3
Placebo		Week 12	93.3	102.0	-8.7
Placebo		Week 12	98.0	91.3	6.7
Placebo		Week 12	100.7	94.0	6.7
Placebo		Week 16	88.0	102.0	-14.0
Placebo		Week 16	98.7	91.3	7.3
Placebo		Week 16	98.7	94.0	4.7
Placebo		Week 2	98.7	102.0	-3.3
Placebo		Week 2	90.7	91.3	-0.7
Placebo		Week 2	90.7	94.0	-3.3
Placebo		Week 20	90.0	102.0	-12.0
Placebo		Week 20	89.3	91.3	-2.0
Placebo		Week 20	90.0	94.0	-4.0
Placebo		Week 24	86.7	102.0	-15.3
Placebo		Week 24	90.0	91.3	-1.3
Placebo		Week 24	83.3	94.0	-10.7
Placebo		Week 4	98.7	102.0	-3.3
Placebo		Week 4	93.3	91.3	2.0
Placebo		Week 4	94.0	94.0	0.0
Placebo		Week 6	95.3	102.0	-6.7
Placebo		Week 6	89.3	91.3	-2.0
Placebo		Week 6	93.3	94.0	-0.7
Placebo		Week 8	99.3	102.0	-2.7
Placebo		Week 8	94.7	91.3	3.3
Placebo		Week 8	94.0	94.0	0.0
Placebo			97.3	102.0
Placebo			97.3	91.3
Placebo			95.3	94.0
Placebo			96.0	102.0
Placebo			89.3	91.3
Placebo			92.7	94.0
Placebo		Week 2	86.0	104.0	-18.0
Placebo		Week 2	77.3	88.7	-11.3
Placebo		Week 2	76.7	88.0	-11.3
Placebo		Week 4	94.0	104.0	-10.0
Placebo		Week 4	94.7	88.7	6.0
Placebo		Week 4	91.3	88.0	3.3
Placebo		Week 6	88.0	104.0	-16.0
Placebo		Week 6	84.7	88.7	-4.0
Placebo		Week 6	86.7	88.0	-1.3
Placebo			104.0	104.0
Placebo			96.7	88.7
Placebo			99.3	88.0
Placebo			85.3	104.0
Placebo			78.0	88.7
Placebo			81.3	88.0
Placebo		Week 12	87.3	86.7	0.7
Placebo		Week 12	94.7	90.7	4.0
Placebo		Week 12	93.3	94.0	-0.7
Placebo		Week 16	108.0	86.7	21.3
Placebo		Week 16	102.7	90.7	12.0
Placebo		Week 16	106.0	94.0	12.0
Placebo		Week 2	90.7	86.7	4.0
Placebo		Week 2	94.7	90.7	4.0
Placebo		Week 2	94.0	94.0	0.0
Placebo		Week 20	106.7	86.7	20.0
Placebo		Week 20	100.0	90.7	9.3
Placebo		Week 20	84.7	94.0	-9.3
Placebo		Week 4	88.0	86.7	1.3
Placebo		Week 4	96.0	90.7	5.3
Placebo		Week 4	92.7	94.0	-1.3
Placebo		Week 6	86.7	86.7	0.0
Placebo		Week 6	94.0	90.7	3.3
Placebo		Week 6	94.0	94.0	0.0
Placebo		Week 8	90.0	86.7	3.3
Placebo		Week 8	92.7	90.7	2.0
Placebo		Week 8	96.0	94.0	2.0
Placebo			90.0	86.7
Placebo			94.0	90.7
Placebo			96.0	94.0
Placebo			87.3	86.7
Placebo			94.0	90.7
Placebo			94.7	94.0
Xanomeline Low Dose		Week 2	93.3	102.0	-8.7
Xanomeline Low Dose		Week 2	85.0	102.0	-17.0
Xanomeline Low Dose		Week 2	85.0	100.7	-15.7
Xanomeline Low Dose			93.3	102.0
Xanomeline Low Dose			83.3	102.0
Xanomeline Low Dose			83.3	100.7
Placebo		Week 12	106.0	108.3	-2.3
Placebo		Week 12	99.3	107.7	-8.3
Placebo		Week 12	103.3	107.7	-4.3
Placebo		Week 16	93.3	108.3	-15.0
Placebo		Week 16	92.7	107.7	-15.0
Placebo		Week 16	92.7	107.7	-15.0
Placebo		Week 2	90.0	108.3	-18.3
Placebo		Week 2	91.7	107.7	-16.0
Placebo		Week 2	91.7	107.7	-16.0
Placebo		Week 4	100.0	108.3	-8.3
Placebo		Week 4	97.3	107.7	-10.3
Placebo		Week 4	99.3	107.7	-8.3
Placebo		Week 6	110.0	108.3	1.7
Placebo		Week 6	100.0	107.7	-7.7
Placebo		Week 6	96.7	107.7	-11.0
Placebo		Week 8	100.0	108.3	-8.3
Placebo		Week 8	98.3	107.7	-9.3
Placebo		Week 8	98.3	107.7	-9.3
Placebo			103.3	108.3
Placebo			100.0	107.7
Placebo			101.3	107.7
Placebo			93.3	108.3
Placebo			96.7	107.7
Placebo			96.7	107.7
Placebo		Week 2	100.0	93.3	6.7
Placebo		Week 2	88.3	91.7	-3.3
Placebo		Week 2	93.3	91.7	1.7
Placebo			90.0	93.3
Placebo			86.0	91.7
Placebo			94.3	91.7
Xanomeline High Dose		Week 12	103.3	80.0	23.3
Xanomeline High Dose		Week 12	101.3	80.0	21.3
Xanomeline High Dose		Week 12	102.0	80.0	22.0
Xanomeline High Dose		Week 16	109.7	80.0	29.7
Xanomeline High Dose		Week 16	105.3	80.0	25.3
Xanomeline High Dose		Week 16	101.3	80.0	21.3
Xanomeline High Dose		Week 2	97.7	80.0	17.7
Xanomeline High Dose		Week 2	99.3	80.0	19.3
Xanomeline High Dose		Week 2	105.3	80.0	25.3
Xanomeline High Dose		Week 20	113.7	80.0	33.7
Xanomeline High Dose		Week 20	107.3	80.0	27.3
Xanomeline High Dose		Week 20	106.7	80.0	26.7
Xanomeline High Dose		Week 24	95.3	80.0	15.3
Xanomeline High Dose		Week 24	93.3	80.0	13.3
Xanomeline High Dose		Week 24	94.7	80.0	14.7
Xanomeline High Dose		Week 26	103.3	80.0	23.3
Xanomeline High Dose		Week 26	103.3	80.0	23.3
Xanomeline High Dose		Week 26	103.3	80.0	23.3
Xanomeline High Dose		Week 4	106.7	80.0	26.7
Xanomeline High Dose		Week 4	106.3	80.0	26.3
Xanomeline High Dose		Week 4	106.0	80.0	26.0
Xanomeline High Dose		Week 6	104.0	80.0	24.0
Xanomeline High Dose		Week 6	96.7	80.0	16.7
Xanomeline High Dose		Week 6	106.7	80.0	26.7
Xanomeline High Dose		Week 8	108.7	80.0	28.7
Xanomeline High Dose		Week 8	104.3	80.0	24.3
Xanomeline High Dose		Week 8	108.7	80.0	28.7
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			86.7	80.0
Xanomeline High Dose			93.3	80.0
Xanomeline High Dose			106.7	80.0
Xanomeline High Dose			100.0	80.0
Xanomeline High Dose			96.7	80.0
Xanomeline High Dose		Week 12	99.3	106.7	-7.3
Xanomeline High Dose		Week 12	106.7	103.3	3.3
Xanomeline High Dose		Week 12	106.7	103.3	3.3
Xanomeline High Dose		Week 2	113.3	106.7	6.7
Xanomeline High Dose		Week 2	115.0	103.3	11.7
Xanomeline High Dose		Week 2	113.3	103.3	10.0
Xanomeline High Dose		Week 4	104.7	106.7	-2.0
Xanomeline High Dose		Week 4	100.0	103.3	-3.3
Xanomeline High Dose		Week 4	103.3	103.3	0.0
Xanomeline High Dose		Week 6	105.0	106.7	-1.7
Xanomeline High Dose		Week 6	103.3	103.3	0.0
Xanomeline High Dose		Week 6	111.7	103.3	8.3
Xanomeline High Dose		Week 8	116.7	106.7	10.0
Xanomeline High Dose		Week 8	103.3	103.3	0.0
Xanomeline High Dose		Week 8	103.3	103.3	0.0
Xanomeline High Dose			100.0	106.7
Xanomeline High Dose			96.0	103.3
Xanomeline High Dose			96.0	103.3
Xanomeline High Dose			103.3	106.7
Xanomeline High Dose			98.7	103.3
Xanomeline High Dose			98.7	103.3
Placebo		Week 12	99.3	86.7	12.7
Placebo		Week 12	106.7	93.3	13.3
Placebo		Week 12	106.7	93.3	13.3
Placebo		Week 16	86.7	86.7	0.0
Placebo		Week 16	83.3	93.3	-10.0
Placebo		Week 16	83.3	93.3	-10.0
Placebo		Week 2	96.0	86.7	9.3
Placebo		Week 2	93.3	93.3	0.0
Placebo		Week 2	93.3	93.3	0.0
Placebo		Week 20	97.3	86.7	10.7
Placebo		Week 20	93.3	93.3	0.0
Placebo		Week 20	93.3	93.3	0.0
Placebo		Week 24	99.3	86.7	12.7
Placebo		Week 24	100.0	93.3	6.7
Placebo		Week 24	98.7	93.3	5.3
Placebo		Week 26	96.7	86.7	10.0
Placebo		Week 26	96.0	93.3	2.7
Placebo		Week 26	96.7	93.3	3.3
Placebo		Week 4	91.7	86.7	5.0
Placebo		Week 4	98.3	93.3	5.0
Placebo		Week 4	96.7	93.3	3.3
Placebo		Week 6	96.7	86.7	10.0
Placebo		Week 6	90.0	93.3	-3.3
Placebo		Week 6	90.0	93.3	-3.3
Placebo		Week 8	99.3	86.7	12.7
Placebo		Week 8	108.3	93.3	15.0
Placebo		Week 8	103.3	93.3	10.0
Placebo			102.7	86.7
Placebo			96.7	93.3
Placebo			96.0	93.3
Placebo			102.7	86.7
Placebo			96.7	93.3
Placebo			96.7	93.3
Xanomeline Low Dose		Week 12	104.0	90.0	14.0
Xanomeline Low Dose		Week 12	103.3	93.3	10.0
Xanomeline Low Dose		Week 12	103.3	93.3	10.0
Xanomeline Low Dose		Week 16	103.3	90.0	13.3
Xanomeline Low Dose		Week 16	102.0	93.3	8.7
Xanomeline Low Dose		Week 16	102.0	93.3	8.7
Xanomeline Low Dose		Week 2	103.3	90.0	13.3
Xanomeline Low Dose		Week 2	102.7	93.3	9.3
Xanomeline Low Dose		Week 2	100.0	93.3	6.7
Xanomeline Low Dose		Week 20	101.7	90.0	11.7
Xanomeline Low Dose		Week 20	103.3	93.3	10.0
Xanomeline Low Dose		Week 20	103.3	93.3	10.0
Xanomeline Low Dose		Week 24	106.7	90.0	16.7
Xanomeline Low Dose		Week 24	106.7	93.3	13.3
Xanomeline Low Dose		Week 24	106.7	93.3	13.3
Xanomeline Low Dose		Week 4	98.0	90.0	8.0
Xanomeline Low Dose		Week 4	95.0	93.3	1.7
Xanomeline Low Dose		Week 4	96.0	93.3	2.7
Xanomeline Low Dose		Week 6	95.0	90.0	5.0
Xanomeline Low Dose		Week 6	93.3	93.3	0.0
Xanomeline Low Dose		Week 6	93.3	93.3	0.0
Xanomeline Low Dose		Week 8	102.7	90.0	12.7
Xanomeline Low Dose		Week 8	115.0	93.3	21.7
Xanomeline Low Dose		Week 8	113.3	93.3	20.0
Xanomeline Low Dose			103.7	90.0
Xanomeline Low Dose			100.0	93.3
Xanomeline Low Dose			100.0	93.3
Xanomeline Low Dose			93.3	90.0
Xanomeline Low Dose			86.7	93.3
Xanomeline Low Dose			86.7	93.3
Xanomeline High Dose		Week 2	102.0	111.7	-9.7
Xanomeline High Dose		Week 2	96.7	113.3	-16.7
Xanomeline High Dose		Week 2	96.7	113.3	-16.7
Xanomeline High Dose			111.7	111.7
Xanomeline High Dose			110.0	113.3
Xanomeline High Dose			110.0	113.3
Xanomeline High Dose		Week 12	75.0	99.3	-24.3
Xanomeline High Dose		Week 12	73.3	93.3	-20.0
Xanomeline High Dose		Week 12	73.3	93.3	-20.0
Xanomeline High Dose		Week 2	106.7	99.3	7.3
Xanomeline High Dose		Week 2	103.3	93.3	10.0
Xanomeline High Dose		Week 2	103.3	93.3	10.0
Xanomeline High Dose		Week 4	100.0	99.3	0.7
Xanomeline High Dose		Week 4	98.3	93.3	5.0
Xanomeline High Dose		Week 4	98.3	93.3	5.0
Xanomeline High Dose		Week 6	110.0	99.3	10.7
Xanomeline High Dose		Week 6	100.3	93.3	7.0
Xanomeline High Dose		Week 6	102.7	93.3	9.3
Xanomeline High Dose		Week 8	105.0	99.3	5.7
Xanomeline High Dose		Week 8	90.0	93.3	-3.3
Xanomeline High Dose		Week 8	93.0	93.3	-0.3
Xanomeline High Dose			86.7	99.3
Xanomeline High Dose			93.3	93.3
Xanomeline High Dose			93.3	93.3
Xanomeline High Dose			110.7	99.3
Xanomeline High Dose			98.7	93.3
Xanomeline High Dose			96.7	93.3
Placebo		Week 12	100.0	101.7	-1.7
Placebo		Week 12	96.7	100.0	-3.3
Placebo		Week 12	96.7	100.0	-3.3
Placebo		Week 16	90.0	101.7	-11.7
Placebo		Week 16	90.0	100.0	-10.0
Placebo		Week 16	90.0	100.0	-10.0
Placebo		Week 2	96.0	101.7	-5.7
Placebo		Week 2	90.0	100.0	-10.0
Placebo		Week 2	90.0	100.0	-10.0
Placebo		Week 20	99.3	101.7	-2.3
Placebo		Week 20	95.0	100.0	-5.0
Placebo		Week 20	95.0	100.0	-5.0
Placebo		Week 24	93.3	101.7	-8.3
Placebo		Week 24	89.3	100.0	-10.7
Placebo		Week 24	88.3	100.0	-11.7
Placebo		Week 26	93.3	101.7	-8.3
Placebo		Week 26	91.7	100.0	-8.3
Placebo		Week 26	90.0	100.0	-10.0
Placebo		Week 4	93.3	101.7	-8.3
Placebo		Week 4	93.3	100.0	-6.7
Placebo		Week 4	93.3	100.0	-6.7
Placebo		Week 6	82.0	101.7	-19.7
Placebo		Week 6	80.0	100.0	-20.0
Placebo		Week 6	87.0	100.0	-13.0
Placebo		Week 8	105.0	101.7	3.3
Placebo		Week 8	103.3	100.0	3.3
Placebo		Week 8	100.0	100.0	0.0
Placebo			93.3	101.7
Placebo			88.7	100.0
Placebo			88.0	100.0
Xanomeline High Dose		Week 2	86.7	77.7	9.0
Xanomeline High Dose		Week 2	89.3	83.3	6.0
Xanomeline High Dose		Week 2	88.0	82.0	6.0
Xanomeline High Dose			93.3	77.7
Xanomeline High Dose			86.7	83.3
Xanomeline High Dose			86.7	82.0
Xanomeline Low Dose		Week 12	123.3	113.3	10.0
Xanomeline Low Dose		Week 12	120.0	111.7	8.3
Xanomeline Low Dose		Week 12	122.0	111.7	10.3
Xanomeline Low Dose		Week 16	115.0	113.3	1.7
Xanomeline Low Dose		Week 16	109.3	111.7	-2.3
Xanomeline Low Dose		Week 16	109.3	111.7	-2.3
Xanomeline Low Dose		Week 2	93.3	113.3	-20.0
Xanomeline Low Dose		Week 2	86.7	111.7	-25.0
Xanomeline Low Dose		Week 2	86.7	111.7	-25.0
Xanomeline Low Dose		Week 4	96.7	113.3	-16.7
Xanomeline Low Dose		Week 4	100.0	111.7	-11.7
Xanomeline Low Dose		Week 4	96.7	111.7	-15.0
Xanomeline Low Dose		Week 6	125.0	113.3	11.7
Xanomeline Low Dose		Week 6	113.3	111.7	1.7
Xanomeline Low Dose		Week 6	106.7	111.7	-5.0
Xanomeline Low Dose		Week 8	90.0	113.3	-23.3
Xanomeline Low Dose		Week 8	90.0	111.7	-21.7
Xanomeline Low Dose		Week 8	86.7	111.7	-25.0
Xanomeline Low Dose			112.0	113.3
Xanomeline Low Dose			100.0	111.7
Xanomeline Low Dose			100.0	111.7
Xanomeline Low Dose			110.0	113.3
Xanomeline Low Dose			100.0	111.7
Xanomeline Low Dose			100.0	111.7
Xanomeline Low Dose		Week 12	81.7	101.7	-20.0
Xanomeline Low Dose		Week 12	76.7	100.0	-23.3
Xanomeline Low Dose		Week 12	71.7	100.0	-28.3
Xanomeline Low Dose		Week 16	88.3	101.7	-13.3
Xanomeline Low Dose		Week 16	86.7	100.0	-13.3
Xanomeline Low Dose		Week 16	86.7	100.0	-13.3
Xanomeline Low Dose		Week 2	92.7	101.7	-9.0
Xanomeline Low Dose		Week 2	91.3	100.0	-8.7
Xanomeline Low Dose		Week 2	90.7	100.0	-9.3
Xanomeline Low Dose		Week 20	90.0	101.7	-11.7
Xanomeline Low Dose		Week 20	90.0	100.0	-10.0
Xanomeline Low Dose		Week 20	90.0	100.0	-10.0
Xanomeline Low Dose		Week 24	76.7	101.7	-25.0
Xanomeline Low Dose		Week 24	76.7	100.0	-23.3
Xanomeline Low Dose		Week 24	76.7	100.0	-23.3
Xanomeline Low Dose		Week 26	80.0	101.7	-21.7
Xanomeline Low Dose		Week 26	75.0	100.0	-25.0
Xanomeline Low Dose		Week 26	75.0	100.0	-25.0
Xanomeline Low Dose		Week 4	90.0	101.7	-11.7
Xanomeline Low Dose		Week 4	84.7	100.0	-15.3
Xanomeline Low Dose		Week 4	83.3	100.0	-16.7
Xanomeline Low Dose		Week 6	100.7	101.7	-1.0
Xanomeline Low Dose		Week 6	94.7	100.0	-5.3
Xanomeline Low Dose		Week 6	92.7	100.0	-7.3
Xanomeline Low Dose		Week 8	70.0	101.7	-31.7
Xanomeline Low Dose		Week 8	73.3	100.0	-26.7
Xanomeline Low Dose		Week 8	73.3	100.0	-26.7
Xanomeline Low Dose			90.7	101.7
Xanomeline Low Dose			88.3	100.0
Xanomeline Low Dose			88.3	100.0
Xanomeline Low Dose			93.3	101.7
Xanomeline Low Dose			83.3	100.0
Xanomeline Low Dose			83.3	100.0
Placebo		Week 12	108.0	100.7	7.3
Placebo		Week 12	102.0	98.0	4.0
Placebo		Week 12	97.0	98.7	-1.7
Placebo		Week 16	99.3	100.7	-1.3
Placebo		Week 16	114.0	98.0	16.0
Placebo		Week 16	107.3	98.7	8.7
Placebo		Week 2	102.0	100.7	1.3
Placebo		Week 2	100.0	98.0	2.0
Placebo		Week 2	96.7	98.7	-2.0
Placebo		Week 20	115.3	100.7	14.7
Placebo		Week 20	120.7	98.0	22.7
Placebo		Week 20	111.3	98.7	12.7
Placebo		Week 24	100.7	100.7	0.0
Placebo		Week 24	110.7	98.0	12.7
Placebo		Week 24	118.0	98.7	19.3
Placebo		Week 4	113.3	100.7	12.7
Placebo		Week 4	111.3	98.0	13.3
Placebo		Week 4	111.3	98.7	12.7
Placebo		Week 6	106.0	100.7	5.3
Placebo		Week 6	103.3	98.0	5.3
Placebo		Week 6	106.0	98.7	7.3
Placebo		Week 8	103.3	100.7	2.7
Placebo		Week 8	100.0	98.0	2.0
Placebo		Week 8	100.7	98.7	2.0
Placebo			100.7	100.7
Placebo			99.3	98.0
Placebo			99.3	98.7
Placebo			114.0	100.7
Placebo			111.3	98.0
Placebo			113.3	98.7
Xanomeline High Dose		Week 2	92.7	93.3	-0.7
Xanomeline High Dose		Week 2	90.0	91.3	-1.3
Xanomeline High Dose		Week 2	89.3	89.3	0.0
Xanomeline High Dose		Week 4	98.7	93.3	5.3
Xanomeline High Dose		Week 4	86.7	91.3	-4.7
Xanomeline High Dose		Week 4	88.7	89.3	-0.7
Xanomeline High Dose			89.3	93.3
Xanomeline High Dose			89.3	91.3
Xanomeline High Dose			86.0	89.3
Xanomeline High Dose			95.3	93.3
Xanomeline High Dose			83.3	91.3
Xanomeline High Dose			84.0	89.3
Placebo		Week 12	98.7	103.3	-4.7
Placebo		Week 12	100.0	100.7	-0.7
Placebo		Week 12	100.7	90.0	10.7
Placebo		Week 16	95.3	103.3	-8.0
Placebo		Week 16	93.3	100.7	-7.3
Placebo		Week 16	98.0	90.0	8.0
Placebo		Week 2	83.3	103.3	-20.0
Placebo		Week 2	81.3	100.7	-19.3
Placebo		Week 2	78.7	90.0	-11.3
Placebo		Week 20	90.0	103.3	-13.3
Placebo		Week 20	76.7	100.7	-24.0
Placebo		Week 20	77.3	90.0	-12.7
Placebo		Week 24	98.0	103.3	-5.3
Placebo		Week 24	96.0	100.7	-4.7
Placebo		Week 24	90.0	90.0	0.0
Placebo		Week 4	82.0	103.3	-21.3
Placebo		Week 4	82.7	100.7	-18.0
Placebo		Week 4	81.3	90.0	-8.7
Placebo		Week 6	103.3	103.3	0.0
Placebo		Week 6	99.3	100.7	-1.3
Placebo		Week 6	106.0	90.0	16.0
Placebo		Week 8	101.3	103.3	-2.0
Placebo		Week 8	97.3	100.7	-3.3
Placebo		Week 8	99.3	90.0	9.3
Placebo			85.3	103.3
Placebo			83.3	100.7
Placebo			84.7	90.0
Placebo			83.3	103.3
Placebo			78.7	100.7
Placebo			83.3	90.0
Xanomeline Low Dose		Week 2	101.3	93.3	8.0
Xanomeline Low Dose		Week 2	101.3	112.0	-10.7
Xanomeline Low Dose		Week 2	103.0	124.7	-21.7
Xanomeline Low Dose			105.0	93.3
Xanomeline Low Dose			108.3	112.0
Xanomeline Low Dose			108.0	124.7
Xanomeline Low Dose		Week 12	76.7	80.0	-3.3
Xanomeline Low Dose		Week 12	76.7	73.3	3.3
Xanomeline Low Dose		Week 12	82.0	90.0	-8.0
Xanomeline Low Dose		Week 16	76.7	80.0	-3.3
Xanomeline Low Dose		Week 16	75.3	73.3	2.0
Xanomeline Low Dose		Week 16	73.3	90.0	-16.7
Xanomeline Low Dose		Week 2	86.7	80.0	6.7
Xanomeline Low Dose		Week 2	81.7	73.3	8.3
Xanomeline Low Dose		Week 2	83.3	90.0	-6.7
Xanomeline Low Dose		Week 20	84.0	80.0	4.0
Xanomeline Low Dose		Week 20	91.3	73.3	18.0
Xanomeline Low Dose		Week 20	94.7	90.0	4.7
Xanomeline Low Dose		Week 24	76.7	80.0	-3.3
Xanomeline Low Dose		Week 24	76.7	73.3	3.3
Xanomeline Low Dose		Week 24	73.3	90.0	-16.7
Xanomeline Low Dose		Week 26	76.0	80.0	-4.0
Xanomeline Low Dose		Week 26	86.7	73.3	13.3
Xanomeline Low Dose		Week 26	83.3	90.0	-6.7
Xanomeline Low Dose		Week 4	86.7	80.0	6.7
Xanomeline Low Dose		Week 4	96.7	73.3	23.3
Xanomeline Low Dose		Week 4	94.0	90.0	4.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	95.3	73.3	22.0
Xanomeline Low Dose		Week 6	84.7	90.0	-5.3
Xanomeline Low Dose		Week 8	83.3	80.0	3.3
Xanomeline Low Dose		Week 8	77.3	73.3	4.0
Xanomeline Low Dose		Week 8	78.7	90.0	-11.3
Xanomeline Low Dose			68.7	80.0
Xanomeline Low Dose			80.0	73.3
Xanomeline Low Dose			81.3	90.0
Xanomeline Low Dose			89.3	80.0
Xanomeline Low Dose			66.7	73.3
Xanomeline Low Dose			76.7	90.0
Placebo		Week 12	106.7	107.3	-0.7
Placebo		Week 12	106.7	95.3	11.3
Placebo		Week 12	106.7	103.3	3.3
Placebo		Week 16	111.3	107.3	4.0
Placebo		Week 16	102.0	95.3	6.7
Placebo		Week 16	110.0	103.3	6.7
Placebo		Week 2	108.0	107.3	0.7
Placebo		Week 2	102.7	95.3	7.3
Placebo		Week 2	106.7	103.3	3.3
Placebo		Week 20	106.7	107.3	-0.7
Placebo		Week 20	99.3	95.3	4.0
Placebo		Week 20	99.3	103.3	-4.0
Placebo		Week 24	106.7	107.3	-0.7
Placebo		Week 24	100.0	95.3	4.7
Placebo		Week 24	104.7	103.3	1.3
Placebo		Week 26	86.7	107.3	-20.7
Placebo		Week 26	90.0	95.3	-5.3
Placebo		Week 26	97.3	103.3	-6.0
Placebo		Week 4	95.3	107.3	-12.0
Placebo		Week 4	100.0	95.3	4.7
Placebo		Week 4	100.3	103.3	-3.0
Placebo		Week 6	102.0	107.3	-5.3
Placebo		Week 6	98.7	95.3	3.3
Placebo		Week 6	101.3	103.3	-2.0
Placebo		Week 8	96.7	107.3	-10.7
Placebo		Week 8	90.0	95.3	-5.3
Placebo		Week 8	106.7	103.3	3.3
Placebo			99.3	107.3
Placebo			98.7	95.3
Placebo			102.7	103.3
Placebo		Week 2	96.0	98.0	-2.0
Placebo		Week 2	90.0	86.7	3.3
Placebo		Week 2	96.7	101.3	-4.7
Placebo		Week 4	116.7	98.0	18.7
Placebo		Week 4	114.7	86.7	28.0
Placebo		Week 4	113.3	101.3	12.0
Placebo			111.3	98.0
Placebo			109.3	86.7
Placebo			109.3	101.3
Placebo			106.0	98.0
Placebo			96.7	86.7
Placebo			102.7	101.3
Placebo		Week 12	86.7	100.0	-13.3
Placebo		Week 12	89.3	96.7	-7.3
Placebo		Week 12	91.3	96.7	-5.3
Placebo		Week 16	90.0	100.0	-10.0
Placebo		Week 16	90.0	96.7	-6.7
Placebo		Week 16	93.3	96.7	-3.3
Placebo		Week 2	109.3	100.0	9.3
Placebo		Week 2	108.7	96.7	12.0
Placebo		Week 2	107.3	96.7	10.7
Placebo		Week 20	86.7	100.0	-13.3
Placebo		Week 20	81.3	96.7	-15.3
Placebo		Week 20	86.0	96.7	-10.7
Placebo		Week 24	86.7	100.0	-13.3
Placebo		Week 24	90.0	96.7	-6.7
Placebo		Week 24	92.7	96.7	-4.0
Placebo		Week 26	104.7	100.0	4.7
Placebo		Week 26	100.7	96.7	4.0
Placebo		Week 26	110.7	96.7	14.0
Placebo		Week 4	106.7	100.0	6.7
Placebo		Week 4	96.7	96.7	0.0
Placebo		Week 4	103.3	96.7	6.7
Placebo		Week 6	93.3	100.0	-6.7
Placebo		Week 6	92.7	96.7	-4.0
Placebo		Week 6	102.7	96.7	6.0
Placebo		Week 8	94.7	100.0	-5.3
Placebo		Week 8	100.0	96.7	3.3
Placebo		Week 8	99.3	96.7	2.7
Placebo			101.3	100.0
Placebo			104.0	96.7
Placebo			104.0	96.7
Placebo			100.0	100.0
Placebo			97.3	96.7
Placebo			98.7	96.7
Xanomeline High Dose		Week 12	103.3	99.3	4.0
Xanomeline High Dose		Week 12	100.0	95.3	4.7
Xanomeline High Dose		Week 12	97.3	106.0	-8.7
Xanomeline High Dose		Week 2	92.0	99.3	-7.3
Xanomeline High Dose		Week 2	97.3	95.3	2.0
Xanomeline High Dose		Week 2	98.7	106.0	-7.3
Xanomeline High Dose		Week 4	91.3	99.3	-8.0
Xanomeline High Dose		Week 4	103.3	95.3	8.0
Xanomeline High Dose		Week 4	96.7	106.0	-9.3
Xanomeline High Dose		Week 6	96.7	99.3	-2.7
Xanomeline High Dose		Week 6	90.0	95.3	-5.3
Xanomeline High Dose		Week 6	90.0	106.0	-16.0
Xanomeline High Dose		Week 8	92.0	99.3	-7.3
Xanomeline High Dose		Week 8	92.0	95.3	-3.3
Xanomeline High Dose		Week 8	95.3	106.0	-10.7
Xanomeline High Dose			106.7	99.3
Xanomeline High Dose			100.0	95.3
Xanomeline High Dose			102.7	106.0
Xanomeline High Dose			96.0	99.3
Xanomeline High Dose			108.7	95.3
Xanomeline High Dose			112.0	106.0
Xanomeline Low Dose		Week 2	104.3	106.7	-2.3
Xanomeline Low Dose		Week 2	123.3	123.3	0.0
Xanomeline Low Dose		Week 2	110.7	120.0	-9.3
Xanomeline High Dose		Week 2	93.3	103.3	-10.0
Xanomeline High Dose		Week 2	90.0	116.0	-26.0
Xanomeline High Dose		Week 2	90.0	119.3	-29.3
Xanomeline High Dose		Week 4	105.0	103.3	1.7
Xanomeline High Dose		Week 4	96.7	116.0	-19.3
Xanomeline High Dose		Week 4	96.7	119.3	-22.7
Xanomeline High Dose			106.7	103.3
Xanomeline High Dose			100.7	116.0
Xanomeline High Dose			99.3	119.3
Xanomeline High Dose			95.3	103.3
Xanomeline High Dose			87.7	116.0
Xanomeline High Dose			102.0	119.3
Placebo		Week 12	110.0	101.3	8.7
Placebo		Week 12	113.3	109.7	3.7
Placebo		Week 12	117.3	110.0	7.3
Placebo		Week 16	116.7	101.3	15.3
Placebo		Week 16	120.7	109.7	11.0
Placebo		Week 16	124.0	110.0	14.0
Placebo		Week 2	99.3	101.3	-2.0
Placebo		Week 2	110.0	109.7	0.3
Placebo		Week 2	109.3	110.0	-0.7
Placebo		Week 20	103.3	101.3	2.0
Placebo		Week 20	104.7	109.7	-5.0
Placebo		Week 20	104.7	110.0	-5.3
Placebo		Week 24	100.0	101.3	-1.3
Placebo		Week 24	95.3	109.7	-14.3
Placebo		Week 24	94.0	110.0	-16.0
Placebo		Week 26	96.7	101.3	-4.7
Placebo		Week 26	101.3	109.7	-8.3
Placebo		Week 26	104.0	110.0	-6.0
Placebo		Week 4	106.7	101.3	5.3
Placebo		Week 4	110.0	109.7	0.3
Placebo		Week 4	112.0	110.0	2.0
Placebo		Week 6	100.0	101.3	-1.3
Placebo		Week 6	92.7	109.7	-17.0
Placebo		Week 6	91.3	110.0	-18.7
Placebo		Week 8	98.7	101.3	-2.7
Placebo		Week 8	100.0	109.7	-9.7
Placebo		Week 8	92.7	110.0	-17.3
Placebo			93.3	101.3
Placebo			110.0	109.7
Placebo			116.7	110.0
Placebo			109.3	101.3
Placebo			110.0	109.7
Placebo			110.0	110.0
Xanomeline Low Dose		Week 2	95.3	105.3	-10.0
Xanomeline Low Dose		Week 2	90.0	112.0	-22.0
Xanomeline Low Dose		Week 2	100.0	116.7	-16.7
Xanomeline Low Dose		Week 4	108.7	105.3	3.3
Xanomeline Low Dose		Week 4	110.0	112.0	-2.0
Xanomeline Low Dose		Week 4	109.3	116.7	-7.3
Xanomeline Low Dose		Week 6	103.3	105.3	-2.0
Xanomeline Low Dose		Week 6	103.3	112.0	-8.7
Xanomeline Low Dose		Week 6	114.0	116.7	-2.7
Xanomeline Low Dose			93.3	105.3
Xanomeline Low Dose			80.0	112.0
Xanomeline Low Dose			93.3	116.7
Xanomeline Low Dose			96.7	105.3
Xanomeline Low Dose			88.0	112.0
Xanomeline Low Dose			92.0	116.7
Placebo		Week 12	98.0	95.3	2.7
Placebo		Week 12	82.7	96.0	-13.3
Placebo		Week 12	97.3	100.7	-3.3
Placebo		Week 16	102.7	95.3	7.3
Placebo		Week 16	98.7	96.0	2.7
Placebo		Week 16	119.3	100.7	18.7
Placebo		Week 2	99.3	95.3	4.0
Placebo		Week 2	92.7	96.0	-3.3
Placebo		Week 2	104.0	100.7	3.3
Placebo		Week 20	96.7	95.3	1.3
Placebo		Week 20	108.7	96.0	12.7
Placebo		Week 20	104.0	100.7	3.3
Placebo		Week 24	82.0	95.3	-13.3
Placebo		Week 24	88.7	96.0	-7.3
Placebo		Week 24	83.3	100.7	-17.3
Placebo		Week 26	99.3	95.3	4.0
Placebo		Week 26	98.0	96.0	2.0
Placebo		Week 26	100.7	100.7	0.0
Placebo		Week 4	102.0	95.3	6.7
Placebo		Week 4	98.0	96.0	2.0
Placebo		Week 4	108.7	100.7	8.0
Placebo		Week 6	98.7	95.3	3.3
Placebo		Week 6	89.3	96.0	-6.7
Placebo		Week 6	98.0	100.7	-2.7
Placebo		Week 8	96.7	95.3	1.3
Placebo		Week 8	92.0	96.0	-4.0
Placebo		Week 8	90.7	100.7	-10.0
Placebo			101.3	95.3
Placebo			94.0	96.0
Placebo			102.7	100.7
Placebo			96.7	95.3
Placebo			94.7	96.0
Placebo			103.3	100.7
Placebo		Week 12	102.7	100.0	2.7
Placebo		Week 12	105.3	100.7	4.7
Placebo		Week 12	113.3	114.7	-1.3
Placebo		Week 16	96.7	100.0	-3.3
Placebo		Week 16	96.0	100.7	-4.7
Placebo		Week 16	103.3	114.7	-11.3
Placebo		Week 2	90.0	100.0	-10.0
Placebo		Week 2	86.7	100.7	-14.0
Placebo		Week 2	94.0	114.7	-20.7
Placebo		Week 20	104.0	100.0	4.0
Placebo		Week 20	104.7	100.7	4.0
Placebo		Week 20	104.7	114.7	-10.0
Placebo		Week 24	98.7	100.0	-1.3
Placebo		Week 24	98.0	100.7	-2.7
Placebo		Week 24	101.3	114.7	-13.3
Placebo		Week 26	106.7	100.0	6.7
Placebo		Week 26	111.3	100.7	10.7
Placebo		Week 26	108.7	114.7	-6.0
Placebo		Week 4	98.0	100.0	-2.0
Placebo		Week 4	102.0	100.7	1.3
Placebo		Week 4	104.7	114.7	-10.0
Placebo		Week 6	96.7	100.0	-3.3
Placebo		Week 6	88.0	100.7	-12.7
Placebo		Week 6	96.7	114.7	-18.0
Placebo		Week 8	98.7	100.0	-1.3
Placebo		Week 8	94.0	100.7	-6.7
Placebo		Week 8	95.3	114.7	-19.3
Placebo			106.7	100.0
Placebo			106.7	100.7
Placebo			112.0	114.7
Placebo			95.3	100.0
Placebo			94.0	100.7
Placebo			93.3	114.7
Xanomeline Low Dose		Week 12	96.0	97.3	-1.3
Xanomeline Low Dose		Week 12	92.0	93.3	-1.3
Xanomeline Low Dose		Week 12	96.0	96.0	0.0
Xanomeline Low Dose		Week 2	84.7	97.3	-12.7
Xanomeline Low Dose		Week 2	100.0	93.3	6.7
Xanomeline Low Dose		Week 2	100.0	96.0	4.0
Xanomeline Low Dose		Week 4	105.3	97.3	8.0
Xanomeline Low Dose		Week 4	104.7	93.3	11.3
Xanomeline Low Dose		Week 4	93.3	96.0	-2.7
Xanomeline Low Dose		Week 6	94.0	97.3	-3.3
Xanomeline Low Dose		Week 6	79.3	93.3	-14.0
Xanomeline Low Dose		Week 6	90.0	96.0	-6.0
Xanomeline Low Dose		Week 8	95.3	97.3	-2.0
Xanomeline Low Dose		Week 8	102.0	93.3	8.7
Xanomeline Low Dose		Week 8	102.0	96.0	6.0
Xanomeline Low Dose			94.7	97.3
Xanomeline Low Dose			93.3	93.3
Xanomeline Low Dose			94.0	96.0
Xanomeline Low Dose			96.0	97.3
Xanomeline Low Dose			102.0	93.3
Xanomeline Low Dose			98.3	96.0
Placebo		Week 12	88.7	106.7	-18.0
Placebo		Week 12	87.3	106.7	-19.3
Placebo		Week 12	88.7	106.7	-18.0
Placebo		Week 16	83.3	106.7	-23.3
Placebo		Week 16	86.0	106.7	-20.7
Placebo		Week 16	83.3	106.7	-23.3
Placebo		Week 2	102.0	106.7	-4.7
Placebo		Week 2	106.7	106.7	0.0
Placebo		Week 2	106.7	106.7	0.0
Placebo		Week 20	96.0	106.7	-10.7
Placebo		Week 20	90.0	106.7	-16.7
Placebo		Week 20	94.7	106.7	-12.0
Placebo		Week 24	97.3	106.7	-9.3
Placebo		Week 24	99.3	106.7	-7.3
Placebo		Week 24	102.0	106.7	-4.7
Placebo		Week 26	106.0	106.7	-0.7
Placebo		Week 26	98.0	106.7	-8.7
Placebo		Week 26	116.7	106.7	10.0
Placebo		Week 4	91.3	106.7	-15.3
Placebo		Week 4	95.3	106.7	-11.3
Placebo		Week 4	94.0	106.7	-12.7
Placebo		Week 6	82.0	106.7	-24.7
Placebo		Week 6	101.3	106.7	-5.3
Placebo		Week 6	106.0	106.7	-0.7
Placebo		Week 8	90.0	106.7	-16.7
Placebo		Week 8	93.3	106.7	-13.3
Placebo		Week 8	93.3	106.7	-13.3
Xanomeline High Dose		Week 12	92.7	90.0	2.7
Xanomeline High Dose		Week 12	97.3	90.0	7.3
Xanomeline High Dose		Week 12	97.3	89.3	8.0
Xanomeline High Dose		Week 16	98.7	90.0	8.7
Xanomeline High Dose		Week 16	96.7	90.0	6.7
Xanomeline High Dose		Week 16	92.7	89.3	3.3
Xanomeline High Dose		Week 2	103.3	90.0	13.3
Xanomeline High Dose		Week 2	98.7	90.0	8.7
Xanomeline High Dose		Week 2	102.0	89.3	12.7
Xanomeline High Dose		Week 20	101.3	90.0	11.3
Xanomeline High Dose		Week 20	96.7	90.0	6.7
Xanomeline High Dose		Week 20	106.0	89.3	16.7
Xanomeline High Dose		Week 24	103.3	90.0	13.3
Xanomeline High Dose		Week 24	98.0	90.0	8.0
Xanomeline High Dose		Week 24	100.0	89.3	10.7
Xanomeline High Dose		Week 26	102.0	90.0	12.0
Xanomeline High Dose		Week 26	96.7	90.0	6.7
Xanomeline High Dose		Week 26	92.7	89.3	3.3
Xanomeline High Dose		Week 4	114.0	90.0	24.0
Xanomeline High Dose		Week 4	104.7	90.0	14.7
Xanomeline High Dose		Week 4	101.3	89.3	12.0
Xanomeline High Dose		Week 6	93.3	90.0	3.3
Xanomeline High Dose		Week 6	90.0	90.0	0.0
Xanomeline High Dose		Week 6	91.3	89.3	2.0
Xanomeline High Dose		Week 8	100.0	90.0	10.0
Xanomeline High Dose		Week 8	100.0	90.0	10.0
Xanomeline High Dose		Week 8	100.0	89.3	10.7
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			88.7	90.0
Xanomeline High Dose			90.0	89.3
Xanomeline High Dose			93.3	90.0
Xanomeline High Dose			90.0	90.0
Xanomeline High Dose			97.3	89.3
Placebo		Week 12	86.7	103.3	-16.7
Placebo		Week 12	92.7	113.3	-20.7
Placebo		Week 12	100.0	113.3	-13.3
Placebo		Week 16	100.0	103.3	-3.3
Placebo		Week 16	108.7	113.3	-4.7
Placebo		Week 16	112.7	113.3	-0.7
Placebo		Week 2	110.7	103.3	7.3
Placebo		Week 2	113.3	113.3	0.0
Placebo		Week 2	113.3	113.3	0.0
Placebo		Week 20	76.7	103.3	-26.7
Placebo		Week 20	98.0	113.3	-15.3
Placebo		Week 20	101.3	113.3	-12.0
Placebo		Week 24	113.3	103.3	10.0
Placebo		Week 24	114.7	113.3	1.3
Placebo		Week 24	113.3	113.3	0.0
Placebo		Week 26	96.7	103.3	-6.7
Placebo		Week 26	102.0	113.3	-11.3
Placebo		Week 26	96.7	113.3	-16.7
Placebo		Week 4	108.0	103.3	4.7
Placebo		Week 4	118.7	113.3	5.3
Placebo		Week 4	119.3	113.3	6.0
Placebo		Week 6	98.3	103.3	-5.0
Placebo		Week 6	113.3	113.3	0.0
Placebo		Week 6	114.0	113.3	0.7
Placebo		Week 8	100.0	103.3	-3.3
Placebo		Week 8	98.7	113.3	-14.7
Placebo		Week 8	97.3	113.3	-16.0
Placebo			118.7	103.3
Placebo			110.0	113.3
Placebo			110.0	113.3
Placebo			102.7	103.3
Placebo			104.0	113.3
Placebo			98.7	113.3
Xanomeline High Dose		Week 12	94.7	108.7	-14.0
Xanomeline High Dose		Week 12	106.7	93.3	13.3
Xanomeline High Dose		Week 12	99.3	98.7	0.7
Xanomeline High Dose		Week 2	100.0	108.7	-8.7
Xanomeline High Dose		Week 2	106.0	93.3	12.7
Xanomeline High Dose		Week 2	108.0	98.7	9.3
Xanomeline High Dose		Week 4	76.7	108.7	-32.0
Xanomeline High Dose		Week 4	79.7	93.3	-13.7
Xanomeline High Dose		Week 4	77.3	98.7	-21.3
Xanomeline High Dose		Week 6	91.3	108.7	-17.3
Xanomeline High Dose		Week 6	94.0	93.3	0.7
Xanomeline High Dose		Week 6	96.7	98.7	-2.0
Xanomeline High Dose		Week 8	88.0	108.7	-20.7
Xanomeline High Dose		Week 8	88.0	93.3	-5.3
Xanomeline High Dose		Week 8	90.0	98.7	-8.7
Xanomeline High Dose			114.0	108.7
Xanomeline High Dose			114.7	93.3
Xanomeline High Dose			118.0	98.7
Xanomeline High Dose			101.3	108.7
Xanomeline High Dose			105.3	93.3
Xanomeline High Dose			105.3	98.7
Xanomeline Low Dose		Week 12	101.3	100.0	1.3
Xanomeline Low Dose		Week 12	97.3	73.3	24.0
Xanomeline Low Dose		Week 12	100.7	83.3	17.3
Xanomeline Low Dose		Week 16	94.7	100.0	-5.3
Xanomeline Low Dose		Week 16	96.7	73.3	23.3
Xanomeline Low Dose		Week 16	97.3	83.3	14.0
Xanomeline Low Dose		Week 2	108.0	100.0	8.0
Xanomeline Low Dose		Week 2	83.3	73.3	10.0
Xanomeline Low Dose		Week 2	86.7	83.3	3.3
Xanomeline Low Dose		Week 20	99.3	100.0	-0.7
Xanomeline Low Dose		Week 20	91.3	73.3	18.0
Xanomeline Low Dose		Week 20	96.0	83.3	12.7
Xanomeline Low Dose		Week 24	100.7	100.0	0.7
Xanomeline Low Dose		Week 24	94.0	73.3	20.7
Xanomeline Low Dose		Week 24	100.0	83.3	16.7
Xanomeline Low Dose		Week 26	91.3	100.0	-8.7
Xanomeline Low Dose		Week 26	78.7	73.3	5.3
Xanomeline Low Dose		Week 26	90.0	83.3	6.7
Xanomeline Low Dose		Week 4	114.7	100.0	14.7
Xanomeline Low Dose		Week 4	118.7	73.3	45.3
Xanomeline Low Dose		Week 4	109.3	83.3	26.0
Xanomeline Low Dose		Week 6	102.7	100.0	2.7
Xanomeline Low Dose		Week 6	100.0	73.3	26.7
Xanomeline Low Dose		Week 6	96.7	83.3	13.3
Xanomeline Low Dose		Week 8	100.7	100.0	0.7
Xanomeline Low Dose		Week 8	102.7	73.3	29.3
Xanomeline Low Dose		Week 8	95.3	83.3	12.0
Xanomeline Low Dose			94.0	100.0
Xanomeline Low Dose			81.3	73.3
Xanomeline Low Dose			98.7	83.3
Xanomeline Low Dose			96.7	100.0
Xanomeline Low Dose			89.3	73.3
Xanomeline Low Dose			100.0	83.3
Xanomeline Low Dose		Week 2	90.7	75.3	15.3
Xanomeline Low Dose		Week 2	98.7	79.3	19.3
Xanomeline Low Dose		Week 2	92.0	81.3	10.7
Xanomeline Low Dose		Week 4	84.0	75.3	8.7
Xanomeline Low Dose		Week 4	92.0	79.3	12.7
Xanomeline Low Dose		Week 4	92.7	81.3	11.3
Xanomeline Low Dose		Week 6	74.7	75.3	-0.7
Xanomeline Low Dose		Week 6	74.0	79.3	-5.3
Xanomeline Low Dose		Week 6	74.0	81.3	-7.3
Xanomeline Low Dose			74.7	75.3
Xanomeline Low Dose			72.7	79.3
Xanomeline Low Dose			77.3	81.3
Placebo		Week 12	84.7	94.0	-9.3
Placebo		Week 12	77.3	87.3	-10.0
Placebo		Week 12	87.3	86.7	0.7
Placebo		Week 16	78.0	94.0	-16.0
Placebo		Week 16	89.3	87.3	2.0
Placebo		Week 16	92.0	86.7	5.3
Placebo		Week 2	90.0	94.0	-4.0
Placebo		Week 2	83.3	87.3	-4.0
Placebo		Week 2	84.7	86.7	-2.0
Placebo		Week 20	80.0	94.0	-14.0
Placebo		Week 20	84.0	87.3	-3.3
Placebo		Week 20	70.0	86.7	-16.7
Placebo		Week 4	97.3	94.0	3.3
Placebo		Week 4	89.3	87.3	2.0
Placebo		Week 4	94.7	86.7	8.0
Placebo		Week 6	94.7	94.0	0.7
Placebo		Week 6	91.3	87.3	4.0
Placebo		Week 6	94.7	86.7	8.0
Placebo		Week 8	82.7	94.0	-11.3
Placebo		Week 8	76.7	87.3	-10.7
Placebo		Week 8	76.7	86.7	-10.0
Placebo			90.0	94.0
Placebo			86.7	87.3
Placebo			86.7	86.7
Xanomeline High Dose		Week 12	111.3	115.3	-4.0
Xanomeline High Dose		Week 12	106.7	110.0	-3.3
Xanomeline High Dose		Week 12	107.3	110.7	-3.3
Xanomeline High Dose		Week 16	102.7	115.3	-12.7
Xanomeline High Dose		Week 16	97.3	110.0	-12.7
Xanomeline High Dose		Week 16	96.7	110.7	-14.0
Xanomeline High Dose		Week 2	106.7	115.3	-8.7
Xanomeline High Dose		Week 2	106.7	110.0	-3.3
Xanomeline High Dose		Week 2	103.3	110.7	-7.3
Xanomeline High Dose		Week 20	90.0	115.3	-25.3
Xanomeline High Dose		Week 20	101.3	110.0	-8.7
Xanomeline High Dose		Week 20	106.7	110.7	-4.0
Xanomeline High Dose		Week 24	116.0	115.3	0.7
Xanomeline High Dose		Week 24	118.7	110.0	8.7
Xanomeline High Dose		Week 24	118.7	110.7	8.0
Xanomeline High Dose		Week 26	101.3	115.3	-14.0
Xanomeline High Dose		Week 26	103.3	110.0	-6.7
Xanomeline High Dose		Week 26	95.3	110.7	-15.3
Xanomeline High Dose		Week 4	116.0	115.3	0.7
Xanomeline High Dose		Week 4	115.3	110.0	5.3
Xanomeline High Dose		Week 4	120.0	110.7	9.3
Xanomeline High Dose		Week 6	94.7	115.3	-20.7
Xanomeline High Dose		Week 6	89.3	110.0	-20.7
Xanomeline High Dose		Week 6	94.0	110.7	-16.7
Xanomeline High Dose		Week 8	96.7	115.3	-18.7
Xanomeline High Dose		Week 8	96.7	110.0	-13.3
Xanomeline High Dose		Week 8	100.7	110.7	-10.0
Xanomeline High Dose			110.0	115.3
Xanomeline High Dose			113.3	110.0
Xanomeline High Dose			110.0	110.7
Xanomeline High Dose			110.0	115.3
Xanomeline High Dose			111.3	110.0
Xanomeline High Dose			106.7	110.7
Xanomeline Low Dose		Week 2	120.0	110.7	9.3
Xanomeline Low Dose		Week 2	116.7	98.7	18.0
Xanomeline Low Dose		Week 2	120.0	98.7	21.3
Xanomeline Low Dose		Week 4	106.7	110.7	-4.0
Xanomeline Low Dose		Week 4	108.0	98.7	9.3
Xanomeline Low Dose		Week 4	106.7	98.7	8.0
Xanomeline Low Dose			113.3	110.7
Xanomeline Low Dose			114.7	98.7
Xanomeline Low Dose			114.0	98.7
Xanomeline Low Dose			93.3	110.7
Xanomeline Low Dose			106.7	98.7
Xanomeline Low Dose			107.3	98.7
Placebo		Week 12	84.7	110.7	-26.0
Placebo		Week 12	91.3	119.3	-28.0
Placebo		Week 12	92.0	119.3	-27.3
Placebo		Week 16	105.3	110.7	-5.3
Placebo		Week 16	106.0	119.3	-13.3
Placebo		Week 16	108.7	119.3	-10.7
Placebo		Week 2	104.0	110.7	-6.7
Placebo		Week 2	107.3	119.3	-12.0
Placebo		Week 2	116.0	119.3	-3.3
Placebo		Week 20	106.0	110.7	-4.7
Placebo		Week 20	106.0	119.3	-13.3
Placebo		Week 20	108.7	119.3	-10.7
Placebo		Week 24	104.7	110.7	-6.0
Placebo		Week 24	101.3	119.3	-18.0
Placebo		Week 24	108.7	119.3	-10.7
Placebo		Week 26	98.7	110.7	-12.0
Placebo		Week 26	103.3	119.3	-16.0
Placebo		Week 26	100.0	119.3	-19.3
Placebo		Week 4	103.3	110.7	-7.3
Placebo		Week 4	98.0	119.3	-21.3
Placebo		Week 4	108.7	119.3	-10.7
Placebo		Week 6	94.0	110.7	-16.7
Placebo		Week 6	86.7	119.3	-32.7
Placebo		Week 6	103.3	119.3	-16.0
Placebo		Week 8	103.3	110.7	-7.3
Placebo		Week 8	98.0	119.3	-21.3
Placebo		Week 8	108.7	119.3	-10.7
Placebo			102.0	110.7
Placebo			103.3	119.3
Placebo			100.0	119.3
Placebo			96.0	110.7
Placebo			103.3	119.3
Placebo			112.0	119.3
Xanomeline Low Dose		Week 2	89.3	98.7	-9.3
Xanomeline Low Dose		Week 2	80.0	93.3	-13.3
Xanomeline Low Dose		Week 2	83.3	92.7	-9.3
Xanomeline Low Dose			92.7	98.7
Xanomeline Low Dose			83.3	93.3
Xanomeline Low Dose			86.7	92.7
Xanomeline Low Dose		Week 12	111.3	102.7	8.7
Xanomeline Low Dose		Week 12	101.3	110.0	-8.7
Xanomeline Low Dose		Week 12	106.7	111.3	-4.7
Xanomeline Low Dose		Week 16	104.7	102.7	2.0
Xanomeline Low Dose		Week 16	94.0	110.0	-16.0
Xanomeline Low Dose		Week 16	90.7	111.3	-20.7
Xanomeline Low Dose		Week 2	116.0	102.7	13.3
Xanomeline Low Dose		Week 2	112.7	110.0	2.7
Xanomeline Low Dose		Week 2	110.0	111.3	-1.3
Xanomeline Low Dose		Week 20	93.3	102.7	-9.3
Xanomeline Low Dose		Week 20	91.3	110.0	-18.7
Xanomeline Low Dose		Week 20	92.0	111.3	-19.3
Xanomeline Low Dose		Week 24	104.7	102.7	2.0
Xanomeline Low Dose		Week 24	100.0	110.0	-10.0
Xanomeline Low Dose		Week 24	92.0	111.3	-19.3
Xanomeline Low Dose		Week 26	96.0	102.7	-6.7
Xanomeline Low Dose		Week 26	92.7	110.0	-17.3
Xanomeline Low Dose		Week 26	94.0	111.3	-17.3
Xanomeline Low Dose		Week 4	118.7	102.7	16.0
Xanomeline Low Dose		Week 4	102.7	110.0	-7.3
Xanomeline Low Dose		Week 4	98.7	111.3	-12.7
Xanomeline Low Dose		Week 6	103.3	102.7	0.7
Xanomeline Low Dose		Week 6	96.0	110.0	-14.0
Xanomeline Low Dose		Week 6	95.3	111.3	-16.0
Xanomeline Low Dose		Week 8	100.7	102.7	-2.0
Xanomeline Low Dose		Week 8	96.7	110.0	-13.3
Xanomeline Low Dose		Week 8	100.7	111.3	-10.7
Xanomeline High Dose		Week 12	90.0	96.0	-6.0
Xanomeline High Dose		Week 12	86.0	89.3	-3.3
Xanomeline High Dose		Week 12	90.0	93.3	-3.3
Xanomeline High Dose		Week 16	98.7	96.0	2.7
Xanomeline High Dose		Week 16	90.0	89.3	0.7
Xanomeline High Dose		Week 16	94.0	93.3	0.7
Xanomeline High Dose		Week 2	94.0	96.0	-2.0
Xanomeline High Dose		Week 2	84.7	89.3	-4.7
Xanomeline High Dose		Week 2	83.3	93.3	-10.0
Xanomeline High Dose		Week 20	88.7	96.0	-7.3
Xanomeline High Dose		Week 20	91.3	89.3	2.0
Xanomeline High Dose		Week 20	86.0	93.3	-7.3
Xanomeline High Dose		Week 24	86.7	96.0	-9.3
Xanomeline High Dose		Week 24	81.3	89.3	-8.0
Xanomeline High Dose		Week 24	92.7	93.3	-0.7
Xanomeline High Dose		Week 26	82.7	96.0	-13.3
Xanomeline High Dose		Week 26	83.3	89.3	-6.0
Xanomeline High Dose		Week 26	74.0	93.3	-19.3
Xanomeline High Dose		Week 4	98.7	96.0	2.7
Xanomeline High Dose		Week 4	106.7	89.3	17.3
Xanomeline High Dose		Week 4	99.3	93.3	6.0
Xanomeline High Dose		Week 6	93.3	96.0	-2.7
Xanomeline High Dose		Week 6	91.3	89.3	2.0
Xanomeline High Dose		Week 6	94.0	93.3	0.7
Xanomeline High Dose		Week 8	92.0	96.0	-4.0
Xanomeline High Dose		Week 8	101.3	89.3	12.0
Xanomeline High Dose		Week 8	92.0	93.3	-1.3
Xanomeline High Dose			88.0	96.0
Xanomeline High Dose			99.3	89.3
Xanomeline High Dose			94.7	93.3
Xanomeline High Dose			93.3	96.0
Xanomeline High Dose			86.7	89.3
Xanomeline High Dose			86.7	93.3
Xanomeline Low Dose		Week 12	85.3	82.7	2.7
Xanomeline Low Dose		Week 12	76.7	83.3	-6.7
Xanomeline Low Dose		Week 12	76.7	82.7	-6.0
Xanomeline Low Dose		Week 2	90.7	82.7	8.0
Xanomeline Low Dose		Week 2	91.3	83.3	8.0
Xanomeline Low Dose		Week 2	85.3	82.7	2.7
Xanomeline Low Dose		Week 4	97.3	82.7	14.7
Xanomeline Low Dose		Week 4	97.3	83.3	14.0
Xanomeline Low Dose		Week 4	98.0	82.7	15.3
Xanomeline Low Dose		Week 6	87.3	82.7	4.7
Xanomeline Low Dose		Week 6	86.7	83.3	3.3
Xanomeline Low Dose		Week 6	87.3	82.7	4.7
Xanomeline Low Dose		Week 8	90.7	82.7	8.0
Xanomeline Low Dose		Week 8	86.0	83.3	2.7
Xanomeline Low Dose		Week 8	96.0	82.7	13.3
Xanomeline Low Dose			90.0	82.7
Xanomeline Low Dose			95.3	83.3
Xanomeline Low Dose			91.3	82.7
Xanomeline Low Dose			79.3	82.7
Xanomeline Low Dose			85.3	83.3
Xanomeline Low Dose			85.3	82.7
Placebo		Week 12	93.3	91.3	2.0
Placebo		Week 12	90.0	90.7	-0.7
Placebo		Week 12	97.3	93.3	4.0
Placebo		Week 16	90.0	91.3	-1.3
Placebo		Week 16	93.3	90.7	2.7
Placebo		Week 16	97.3	93.3	4.0
Placebo		Week 2	96.0	91.3	4.7
Placebo		Week 2	86.0	90.7	-4.7
Placebo		Week 2	88.0	93.3	-5.3
Placebo		Week 20	98.7	91.3	7.3
Placebo		Week 20	95.3	90.7	4.7
Placebo		Week 20	98.7	93.3	5.3
Placebo		Week 24	96.0	91.3	4.7
Placebo		Week 24	92.7	90.7	2.0
Placebo		Week 24	92.0	93.3	-1.3
Placebo		Week 26	93.3	91.3	2.0
Placebo		Week 26	92.7	90.7	2.0
Placebo		Week 26	86.0	93.3	-7.3
Placebo		Week 4	96.7	91.3	5.3
Placebo		Week 4	92.0	90.7	1.3
Placebo		Week 4	93.3	93.3	0.0
Placebo		Week 6	93.3	91.3	2.0
Placebo		Week 6	88.7	90.7	-2.0
Placebo		Week 6	91.3	93.3	-2.0
Placebo		Week 8	102.0	91.3	10.7
Placebo		Week 8	96.7	90.7	6.0
Placebo		Week 8	99.3	93.3	6.0
Placebo			98.0	91.3
Placebo			93.3	90.7
Placebo			89.3	93.3
Placebo			95.3	91.3
Placebo			93.3	90.7
Placebo			90.7	93.3
Xanomeline High Dose		Week 12	98.0	100.0	-2.0
Xanomeline High Dose		Week 12	93.3	103.3	-10.0
Xanomeline High Dose		Week 12	93.3	105.3	-12.0
Xanomeline High Dose		Week 16	99.3	100.0	-0.7
Xanomeline High Dose		Week 16	93.3	103.3	-10.0
Xanomeline High Dose		Week 16	89.3	105.3	-16.0
Xanomeline High Dose		Week 2	96.0	100.0	-4.0
Xanomeline High Dose		Week 2	103.3	103.3	0.0
Xanomeline High Dose		Week 2	98.7	105.3	-6.7
Xanomeline High Dose		Week 20	83.3	100.0	-16.7
Xanomeline High Dose		Week 20	86.0	103.3	-17.3
Xanomeline High Dose		Week 20	86.0	105.3	-19.3
Xanomeline High Dose		Week 24	96.7	100.0	-3.3
Xanomeline High Dose		Week 24	100.0	103.3	-3.3
Xanomeline High Dose		Week 24	100.0	105.3	-5.3
Xanomeline High Dose		Week 26	82.7	100.0	-17.3
Xanomeline High Dose		Week 26	84.7	103.3	-18.7
Xanomeline High Dose		Week 26	90.7	105.3	-14.7
Xanomeline High Dose		Week 4	100.7	100.0	0.7
Xanomeline High Dose		Week 4	96.7	103.3	-6.7
Xanomeline High Dose		Week 4	97.3	105.3	-8.0
Xanomeline High Dose		Week 6	86.7	100.0	-13.3
Xanomeline High Dose		Week 6	89.3	103.3	-14.0
Xanomeline High Dose		Week 6	85.3	105.3	-20.0
Xanomeline High Dose		Week 8	101.3	100.0	1.3
Xanomeline High Dose		Week 8	108.0	103.3	4.7
Xanomeline High Dose		Week 8	104.0	105.3	-1.3
Xanomeline High Dose			97.3	100.0
Xanomeline High Dose			89.3	103.3
Xanomeline High Dose			93.3	105.3
Xanomeline High Dose			93.3	100.0
Xanomeline High Dose			93.3	103.3
Xanomeline High Dose			96.0	105.3
Xanomeline Low Dose		Week 2	90.0	90.0	0.0
Xanomeline Low Dose		Week 2	93.3	72.7	20.7
Xanomeline Low Dose		Week 2	92.7	88.7	4.0
Xanomeline Low Dose		Week 4	94.7	90.0	4.7
Xanomeline Low Dose		Week 4	96.0	72.7	23.3
Xanomeline Low Dose		Week 4	102.7	88.7	14.0
Xanomeline Low Dose		Week 6	96.7	90.0	6.7
Xanomeline Low Dose		Week 6	94.7	72.7	22.0
Xanomeline Low Dose		Week 6	99.3	88.7	10.7
Xanomeline Low Dose		Week 8	102.7	90.0	12.7
Xanomeline Low Dose		Week 8	98.0	72.7	25.3
Xanomeline Low Dose		Week 8	95.3	88.7	6.7
Xanomeline Low Dose			107.3	90.0
Xanomeline Low Dose			96.7	72.7
Xanomeline Low Dose			93.3	88.7
Xanomeline Low Dose			97.3	90.0
Xanomeline Low Dose			84.0	72.7
Xanomeline Low Dose			86.0	88.7
Xanomeline High Dose		Week 2	96.0	102.7	-6.7
Xanomeline High Dose		Week 2	91.3	101.3	-10.0
Xanomeline High Dose		Week 2	88.0	94.0	-6.0
Xanomeline High Dose		Week 4	97.3	102.7	-5.3
Xanomeline High Dose		Week 4	104.7	101.3	3.3
Xanomeline High Dose		Week 4	96.7	94.0	2.7
Xanomeline High Dose		Week 6	102.7	102.7	0.0
Xanomeline High Dose		Week 6	95.3	101.3	-6.0
Xanomeline High Dose		Week 6	96.0	94.0	2.0
Xanomeline High Dose			104.7	102.7
Xanomeline High Dose			92.7	101.3
Xanomeline High Dose			90.0	94.0
Xanomeline Low Dose		Week 12	82.0	88.7	-6.7
Xanomeline Low Dose		Week 12	79.3	90.7	-11.3
Xanomeline Low Dose		Week 12	83.3	88.0	-4.7
Xanomeline Low Dose		Week 2	89.3	88.7	0.7
Xanomeline Low Dose		Week 2	90.0	90.7	-0.7
Xanomeline Low Dose		Week 2	89.3	88.0	1.3
Xanomeline Low Dose		Week 4	90.0	88.7	1.3
Xanomeline Low Dose		Week 4	90.7	90.7	0.0
Xanomeline Low Dose		Week 4	90.0	88.0	2.0
Xanomeline Low Dose		Week 6	89.3	88.7	0.7
Xanomeline Low Dose		Week 6	88.7	90.7	-2.0
Xanomeline Low Dose		Week 6	88.0	88.0	0.0
Xanomeline Low Dose		Week 8	86.7	88.7	-2.0
Xanomeline Low Dose		Week 8	87.3	90.7	-3.3
Xanomeline Low Dose		Week 8	87.3	88.0	-0.7
Xanomeline Low Dose			87.3	88.7
Xanomeline Low Dose			98.0	90.7
Xanomeline Low Dose			104.0	88.0
Xanomeline Low Dose			86.7	88.7
Xanomeline Low Dose			93.3	90.7
Xanomeline Low Dose			83.3	88.0
Xanomeline High Dose		Week 2	106.7	98.0	8.7
Xanomeline High Dose		Week 2	93.3	102.7	-9.3
Xanomeline High Dose		Week 2	98.7	106.0	-7.3
Xanomeline High Dose		Week 4	96.7	98.0	-1.3
Xanomeline High Dose		Week 4	104.7	102.7	2.0
Xanomeline High Dose		Week 4	101.3	106.0	-4.7
Xanomeline High Dose		Week 6	91.3	98.0	-6.7
Xanomeline High Dose		Week 6	87.3	102.7	-15.3
Xanomeline High Dose		Week 6	83.3	106.0	-22.7
Xanomeline High Dose		Week 8	99.3	98.0	1.3
Xanomeline High Dose		Week 8	93.3	102.7	-9.3
Xanomeline High Dose		Week 8	92.0	106.0	-14.0
Xanomeline High Dose			99.3	98.0
Xanomeline High Dose			104.7	102.7
Xanomeline High Dose			102.0	106.0
Placebo		Week 12	73.3	78.7	-5.3
Placebo		Week 12	66.7	78.0	-11.3
Placebo		Week 12	66.0	78.7	-12.7
Placebo		Week 16	78.7	78.7	0.0
Placebo		Week 16	69.3	78.0	-8.7
Placebo		Week 16	76.7	78.7	-2.0
Placebo		Week 2	79.3	78.7	0.7
Placebo		Week 2	82.7	78.0	4.7
Placebo		Week 2	76.0	78.7	-2.7
Placebo		Week 20	78.7	78.7	0.0
Placebo		Week 20	72.7	78.0	-5.3
Placebo		Week 20	74.7	78.7	-4.0
Placebo		Week 4	71.3	78.7	-7.3
Placebo		Week 4	70.0	78.0	-8.0
Placebo		Week 4	74.0	78.7	-4.7
Placebo		Week 6	80.0	78.7	1.3
Placebo		Week 6	75.3	78.0	-2.7
Placebo		Week 6	86.7	78.7	8.0
Placebo		Week 8	88.0	78.7	9.3
Placebo		Week 8	85.3	78.0	7.3
Placebo		Week 8	79.3	78.7	0.7
Placebo			75.3	78.7
Placebo			73.3	78.0
Placebo			72.7	78.7
Placebo			82.7	78.7
Placebo			77.3	78.0
Placebo			80.0	78.7
Xanomeline Low Dose		Week 2	98.0	100.7	-2.7
Xanomeline Low Dose		Week 2	102.7	105.3	-2.7
Xanomeline Low Dose		Week 2	102.7	108.0	-5.3
Xanomeline Low Dose		Week 4	100.0	100.7	-0.7
Xanomeline Low Dose		Week 4	106.7	105.3	1.3
Xanomeline Low Dose		Week 4	111.3	108.0	3.3
Xanomeline Low Dose		Week 6	100.0	100.7	-0.7
Xanomeline Low Dose		Week 6	110.0	105.3	4.7
Xanomeline Low Dose		Week 6	108.0	108.0	0.0
Xanomeline Low Dose		Week 8	88.7	100.7	-12.0
Xanomeline Low Dose		Week 8	93.3	105.3	-12.0
Xanomeline Low Dose		Week 8	103.3	108.0	-4.7
Xanomeline Low Dose			102.7	100.7
Xanomeline Low Dose			106.7	105.3
Xanomeline Low Dose			104.7	108.0
Xanomeline Low Dose			105.3	100.7
Xanomeline Low Dose			113.3	105.3
Xanomeline Low Dose			117.3	108.0
Placebo		Week 12	92.0	105.3	-13.3
Placebo		Week 12	92.0	98.7	-6.7
Placebo		Week 12	87.3	96.0	-8.7
Placebo		Week 16	101.3	105.3	-4.0
Placebo		Week 16	94.7	98.7	-4.0
Placebo		Week 16	103.3	96.0	7.3
Placebo		Week 2	101.3	105.3	-4.0
Placebo		Week 2	103.3	98.7	4.7
Placebo		Week 2	100.7	96.0	4.7
Placebo		Week 20	90.7	105.3	-14.7
Placebo		Week 20	89.3	98.7	-9.3
Placebo		Week 20	88.0	96.0	-8.0
Placebo		Week 24	95.3	105.3	-10.0
Placebo		Week 24	91.3	98.7	-7.3
Placebo		Week 24	96.7	96.0	0.7
Placebo		Week 26	107.3	105.3	2.0
Placebo		Week 26	100.0	98.7	1.3
Placebo		Week 26	96.7	96.0	0.7
Placebo		Week 4	95.3	105.3	-10.0
Placebo		Week 4	96.7	98.7	-2.0
Placebo		Week 4	94.7	96.0	-1.3
Placebo		Week 6	107.3	105.3	2.0
Placebo		Week 6	96.7	98.7	-2.0
Placebo		Week 6	96.0	96.0	0.0
Placebo		Week 8	104.7	105.3	-0.7
Placebo		Week 8	106.0	98.7	7.3
Placebo		Week 8	102.7	96.0	6.7
Placebo			100.0	105.3
Placebo			93.3	98.7
Placebo			98.7	96.0
Placebo			93.3	105.3
Placebo			99.3	98.7
Placebo			98.7	96.0
Placebo		Week 12	100.0	104.0	-4.0
Placebo		Week 12	93.3	106.0	-12.7
Placebo		Week 12	101.3	99.3	2.0
Placebo		Week 16	98.0	104.0	-6.0
Placebo		Week 16	94.0	106.0	-12.0
Placebo		Week 16	93.3	99.3	-6.0
Placebo		Week 2	92.7	104.0	-11.3
Placebo		Week 2	83.3	106.0	-22.7
Placebo		Week 2	90.7	99.3	-8.7
Placebo		Week 4	98.0	104.0	-6.0
Placebo		Week 4	103.3	106.0	-2.7
Placebo		Week 4	106.0	99.3	6.7
Placebo		Week 6	93.3	104.0	-10.7
Placebo		Week 6	96.7	106.0	-9.3
Placebo		Week 6	95.3	99.3	-4.0
Placebo		Week 8	99.3	104.0	-4.7
Placebo		Week 8	100.0	106.0	-6.0
Placebo		Week 8	97.3	99.3	-2.0
Placebo			100.0	104.0
Placebo			98.7	106.0
Placebo			92.0	99.3
Placebo			106.0	104.0
Placebo			114.7	106.0
Placebo			110.0	99.3
Xanomeline High Dose		Week 12	95.3	90.0	5.3
Xanomeline High Dose		Week 12	97.3	96.0	1.3
Xanomeline High Dose		Week 12	98.0	92.7	5.3
Xanomeline High Dose		Week 16	90.7	90.0	0.7
Xanomeline High Dose		Week 16	95.3	96.0	-0.7
Xanomeline High Dose		Week 16	92.7	92.7	0.0
Xanomeline High Dose		Week 2	96.7	90.0	6.7
Xanomeline High Dose		Week 2	102.7	96.0	6.7
Xanomeline High Dose		Week 2	104.7	92.7	12.0
Xanomeline High Dose		Week 20	91.3	90.0	1.3
Xanomeline High Dose		Week 20	95.3	96.0	-0.7
Xanomeline High Dose		Week 20	93.3	92.7	0.7
Xanomeline High Dose		Week 24	76.7	90.0	-13.3
Xanomeline High Dose		Week 24	81.3	96.0	-14.7
Xanomeline High Dose		Week 24	86.7	92.7	-6.0
Xanomeline High Dose		Week 26	86.0	90.0	-4.0
Xanomeline High Dose		Week 26	98.0	96.0	2.0
Xanomeline High Dose		Week 26	94.7	92.7	2.0
Xanomeline High Dose		Week 4	96.7	90.0	6.7
Xanomeline High Dose		Week 4	94.0	96.0	-2.0
Xanomeline High Dose		Week 4	94.7	92.7	2.0
Xanomeline High Dose		Week 6	102.7	90.0	12.7
Xanomeline High Dose		Week 6	101.3	96.0	5.3
Xanomeline High Dose		Week 6	101.3	92.7	8.7
Xanomeline High Dose		Week 8	92.7	90.0	2.7
Xanomeline High Dose		Week 8	100.0	96.0	4.0
Xanomeline High Dose		Week 8	100.7	92.7	8.0
Xanomeline High Dose			96.7	90.0
Xanomeline High Dose			104.0	96.0
Xanomeline High Dose			99.3	92.7
Xanomeline High Dose			101.3	90.0
Xanomeline High Dose			96.0	96.0
Xanomeline High Dose			106.0	92.7
Placebo		Week 12	88.0	110.0	-22.0
Placebo		Week 12	83.3	104.0	-20.7
Placebo		Week 12	87.3	99.3	-12.0
Placebo		Week 16	102.0	110.0	-8.0
Placebo		Week 16	92.7	104.0	-11.3
Placebo		Week 16	96.7	99.3	-2.7
Placebo		Week 2	92.0	110.0	-18.0
Placebo		Week 2	76.7	104.0	-27.3
Placebo		Week 2	82.7	99.3	-16.7
Placebo		Week 20	98.0	110.0	-12.0
Placebo		Week 20	88.0	104.0	-16.0
Placebo		Week 20	95.3	99.3	-4.0
Placebo		Week 24	98.7	110.0	-11.3
Placebo		Week 24	94.7	104.0	-9.3
Placebo		Week 24	103.3	99.3	4.0
Placebo		Week 26	88.0	110.0	-22.0
Placebo		Week 26	86.0	104.0	-18.0
Placebo		Week 26	93.3	99.3	-6.0
Placebo		Week 4	94.0	110.0	-16.0
Placebo		Week 4	76.0	104.0	-28.0
Placebo		Week 4	83.3	99.3	-16.0
Placebo		Week 6	94.7	110.0	-15.3
Placebo		Week 6	103.3	104.0	-0.7
Placebo		Week 6	101.3	99.3	2.0
Placebo		Week 8	92.7	110.0	-17.3
Placebo		Week 8	82.7	104.0	-21.3
Placebo		Week 8	93.3	99.3	-6.0
Placebo			103.3	110.0
Placebo			98.0	104.0
Placebo			97.3	99.3
Xanomeline Low Dose		Week 12	114.7	106.7	8.0
Xanomeline Low Dose		Week 12	118.7	113.3	5.3
Xanomeline Low Dose		Week 12	110.0	121.3	-11.3
Xanomeline Low Dose		Week 16	113.3	106.7	6.7
Xanomeline Low Dose		Week 16	118.7	113.3	5.3
Xanomeline Low Dose		Week 16	115.3	121.3	-6.0
Xanomeline Low Dose		Week 2	114.0	106.7	7.3
Xanomeline Low Dose		Week 2	124.7	113.3	11.3
Xanomeline Low Dose		Week 2	124.7	121.3	3.3
Xanomeline Low Dose		Week 20	112.0	106.7	5.3
Xanomeline Low Dose		Week 20	118.7	113.3	5.3
Xanomeline Low Dose		Week 20	110.0	121.3	-11.3
Xanomeline Low Dose		Week 24	110.0	106.7	3.3
Xanomeline Low Dose		Week 24	112.0	113.3	-1.3
Xanomeline Low Dose		Week 24	112.7	121.3	-8.7
Xanomeline Low Dose		Week 26	103.3	106.7	-3.3
Xanomeline Low Dose		Week 26	111.3	113.3	-2.0
Xanomeline Low Dose		Week 26	110.0	121.3	-11.3
Xanomeline Low Dose		Week 4	115.3	106.7	8.7
Xanomeline Low Dose		Week 4	118.7	113.3	5.3
Xanomeline Low Dose		Week 4	120.0	121.3	-1.3
Xanomeline Low Dose		Week 6	116.7	106.7	10.0
Xanomeline Low Dose		Week 6	120.7	113.3	7.3
Xanomeline Low Dose		Week 6	122.0	121.3	0.7
Xanomeline Low Dose		Week 8	108.0	106.7	1.3
Xanomeline Low Dose		Week 8	114.0	113.3	0.7
Xanomeline Low Dose		Week 8	113.3	121.3	-8.0
Xanomeline Low Dose			107.3	106.7
Xanomeline Low Dose			110.7	113.3
Xanomeline Low Dose			115.3	121.3
Xanomeline Low Dose			109.3	106.7
Xanomeline Low Dose			112.7	113.3
Xanomeline Low Dose			114.0	121.3
Placebo		Week 12	92.0	88.7	3.3
Placebo		Week 12	91.3	89.3	2.0
Placebo		Week 12	89.3	98.0	-8.7
Placebo		Week 16	91.3	88.7	2.7
Placebo		Week 16	88.0	89.3	-1.3
Placebo		Week 16	94.0	98.0	-4.0
Placebo		Week 2	90.0	88.7	1.3
Placebo		Week 2	88.7	89.3	-0.7
Placebo		Week 2	88.0	98.0	-10.0
Placebo		Week 20	103.3	88.7	14.7
Placebo		Week 20	98.7	89.3	9.3
Placebo		Week 20	98.7	98.0	0.7
Placebo		Week 24	83.3	88.7	-5.3
Placebo		Week 24	98.7	89.3	9.3
Placebo		Week 24	94.7	98.0	-3.3
Placebo		Week 26	93.3	88.7	4.7
Placebo		Week 26	93.3	89.3	4.0
Placebo		Week 26	93.3	98.0	-4.7
Placebo		Week 4	90.0	88.7	1.3
Placebo		Week 4	92.7	89.3	3.3
Placebo		Week 4	92.7	98.0	-5.3
Placebo		Week 6	90.0	88.7	1.3
Placebo		Week 6	92.7	89.3	3.3
Placebo		Week 6	96.7	98.0	-1.3
Placebo		Week 8	84.7	88.7	-4.0
Placebo		Week 8	98.0	89.3	8.7
Placebo		Week 8	96.0	98.0	-2.0
Placebo			100.7	88.7
Placebo			96.7	89.3
Placebo			100.0	98.0
Placebo			88.7	88.7
Placebo			86.0	89.3
Placebo			86.7	98.0
Xanomeline Low Dose		Week 2	96.7	97.3	-0.7
Xanomeline Low Dose		Week 2	98.0	100.0	-2.0
Xanomeline Low Dose		Week 2	98.7	102.0	-3.3
Xanomeline High Dose		Week 12	87.3	100.0	-12.7
Xanomeline High Dose		Week 12	84.7	112.7	-28.0
Xanomeline High Dose		Week 12	86.7	108.0	-21.3
Xanomeline High Dose		Week 16	101.3	100.0	1.3
Xanomeline High Dose		Week 16	100.7	112.7	-12.0
Xanomeline High Dose		Week 16	100.7	108.0	-7.3
Xanomeline High Dose		Week 2	96.7	100.0	-3.3
Xanomeline High Dose		Week 2	98.0	112.7	-14.7
Xanomeline High Dose		Week 2	97.3	108.0	-10.7
Xanomeline High Dose		Week 20	86.7	100.0	-13.3
Xanomeline High Dose		Week 20	96.0	112.7	-16.7
Xanomeline High Dose		Week 20	93.3	108.0	-14.7
Xanomeline High Dose		Week 24	96.7	100.0	-3.3
Xanomeline High Dose		Week 24	100.0	112.7	-12.7
Xanomeline High Dose		Week 24	98.0	108.0	-10.0
Xanomeline High Dose		Week 4	103.3	100.0	3.3
Xanomeline High Dose		Week 4	102.0	112.7	-10.7
Xanomeline High Dose		Week 4	100.0	108.0	-8.0
Xanomeline High Dose		Week 6	96.0	100.0	-4.0
Xanomeline High Dose		Week 6	99.3	112.7	-13.3
Xanomeline High Dose		Week 6	97.3	108.0	-10.7
Xanomeline High Dose		Week 8	94.7	100.0	-5.3
Xanomeline High Dose		Week 8	98.0	112.7	-14.7
Xanomeline High Dose		Week 8	96.0	108.0	-12.0
Xanomeline High Dose			106.0	100.0
Xanomeline High Dose			105.3	112.7
Xanomeline High Dose			102.7	108.0
Xanomeline High Dose			104.0	100.0
Xanomeline High Dose			99.3	112.7
Xanomeline High Dose			102.7	108.0
Xanomeline High Dose		Week 2	102.0	107.3	-5.3
Xanomeline High Dose		Week 2	98.0	100.0	-2.0
Xanomeline High Dose		Week 2	98.0	98.0	0.0
Xanomeline High Dose		Week 4	103.3	107.3	-4.0
Xanomeline High Dose		Week 4	100.7	100.0	0.7
Xanomeline High Dose		Week 4	101.3	98.0	3.3
Xanomeline High Dose			103.3	107.3
Xanomeline High Dose			102.0	100.0
Xanomeline High Dose			102.0	98.0
Xanomeline High Dose			96.0	107.3
Xanomeline High Dose			96.0	100.0
Xanomeline High Dose			94.0	98.0
Placebo		Week 12	86.7	102.7	-16.0
Placebo		Week 12	90.0	99.3	-9.3
Placebo		Week 12	93.3	102.0	-8.7
Placebo		Week 16	81.3	102.7	-21.3
Placebo		Week 16	80.7	99.3	-18.7
Placebo		Week 16	78.7	102.0	-23.3
Placebo		Week 2	90.0	102.7	-12.7
Placebo		Week 2	88.0	99.3	-11.3
Placebo		Week 2	91.3	102.0	-10.7
Placebo		Week 20	86.7	102.7	-16.0
Placebo		Week 20	86.0	99.3	-13.3
Placebo		Week 20	86.7	102.0	-15.3
Placebo		Week 24	100.0	102.7	-2.7
Placebo		Week 24	102.7	99.3	3.3
Placebo		Week 24	100.0	102.0	-2.0
Placebo		Week 26	96.7	102.7	-6.0
Placebo		Week 26	91.3	99.3	-8.0
Placebo		Week 26	90.7	102.0	-11.3
Placebo		Week 4	86.7	102.7	-16.0
Placebo		Week 4	88.7	99.3	-10.7
Placebo		Week 4	88.0	102.0	-14.0
Placebo		Week 6	100.0	102.7	-2.7
Placebo		Week 6	92.7	99.3	-6.7
Placebo		Week 6	95.3	102.0	-6.7
Placebo		Week 8	86.7	102.7	-16.0
Placebo		Week 8	86.0	99.3	-13.3
Placebo		Week 8	88.0	102.0	-14.0
Xanomeline Low Dose		Week 2	110.0	113.3	-3.3
Xanomeline Low Dose		Week 2	112.0	116.7	-4.7
Xanomeline Low Dose		Week 2	110.0	116.7	-6.7
Xanomeline Low Dose		Week 4	100.0	113.3	-13.3
Xanomeline Low Dose		Week 4	99.3	116.7	-17.3
Xanomeline Low Dose		Week 4	98.7	116.7	-18.0
Xanomeline Low Dose		Week 6	103.3	113.3	-10.0
Xanomeline Low Dose		Week 6	108.0	116.7	-8.7
Xanomeline Low Dose		Week 6	105.0	116.7	-11.7
Xanomeline Low Dose		Week 8	112.7	113.3	-0.7
Xanomeline Low Dose		Week 8	114.7	116.7	-2.0
Xanomeline Low Dose		Week 8	112.7	116.7	-4.0
Xanomeline Low Dose			110.0	113.3
Xanomeline Low Dose			115.3	116.7
Xanomeline Low Dose			113.3	116.7
Xanomeline Low Dose			103.3	113.3
Xanomeline Low Dose			107.3	116.7
Xanomeline Low Dose			104.7	116.7
Xanomeline Low Dose		Week 2	102.7	106.7	-4.0
Xanomeline Low Dose		Week 2	96.0	100.7	-4.7
Xanomeline Low Dose		Week 2	99.3	100.0	-0.7
Xanomeline Low Dose		Week 4	102.7	106.7	-4.0
Xanomeline Low Dose		Week 4	104.7	100.7	4.0
Xanomeline Low Dose		Week 4	104.0	100.0	4.0
Xanomeline Low Dose		Week 6	95.3	106.7	-11.3
Xanomeline Low Dose		Week 6	102.7	100.7	2.0
Xanomeline Low Dose		Week 6	99.3	100.0	-0.7
Xanomeline Low Dose			82.0	106.7
Xanomeline Low Dose			91.3	100.7
Xanomeline Low Dose			88.0	100.0
Xanomeline Low Dose			86.0	106.7
Xanomeline Low Dose			88.3	100.7
Xanomeline Low Dose			86.3	100.0
Placebo		Week 12	98.0	83.3	14.7
Placebo		Week 12	104.0	93.3	10.7
Placebo		Week 12	103.3	90.0	13.3
Placebo		Week 16	110.0	83.3	26.7
Placebo		Week 16	116.0	93.3	22.7
Placebo		Week 16	116.7	90.0	26.7
Placebo		Week 2	110.0	83.3	26.7
Placebo		Week 2	112.7	93.3	19.3
Placebo		Week 2	110.7	90.0	20.7
Placebo		Week 20	100.0	83.3	16.7
Placebo		Week 20	106.0	93.3	12.7
Placebo		Week 20	104.0	90.0	14.0
Placebo		Week 24	117.3	83.3	34.0
Placebo		Week 24	118.0	93.3	24.7
Placebo		Week 24	116.0	90.0	26.0
Placebo		Week 26	110.7	83.3	27.3
Placebo		Week 26	109.3	93.3	16.0
Placebo		Week 26	109.3	90.0	19.3
Placebo		Week 4	113.3	83.3	30.0
Placebo		Week 4	111.3	93.3	18.0
Placebo		Week 4	110.7	90.0	20.7
Placebo		Week 6	96.0	83.3	12.7
Placebo		Week 6	98.3	93.3	5.0
Placebo		Week 6	96.7	90.0	6.7
Placebo		Week 8	113.3	83.3	30.0
Placebo		Week 8	108.7	93.3	15.3
Placebo		Week 8	106.7	90.0	16.7
Placebo			103.3	83.3
Placebo			99.3	93.3
Placebo			100.7	90.0
Placebo			100.0	83.3
Placebo			102.0	93.3
Placebo			101.3	90.0
Xanomeline High Dose		Week 12	113.3	96.7	16.7
Xanomeline High Dose		Week 12	114.0	102.0	12.0
Xanomeline High Dose		Week 12	112.0	102.7	9.3
Xanomeline High Dose		Week 16	95.3	96.7	-1.3
Xanomeline High Dose		Week 16	99.3	102.0	-2.7
Xanomeline High Dose		Week 16	100.0	102.7	-2.7
Xanomeline High Dose		Week 2	88.7	96.7	-8.0
Xanomeline High Dose		Week 2	90.0	102.0	-12.0
Xanomeline High Dose		Week 2	89.3	102.7	-13.3
Xanomeline High Dose		Week 4	108.7	96.7	12.0
Xanomeline High Dose		Week 4	104.0	102.0	2.0
Xanomeline High Dose		Week 4	106.0	102.7	3.3
Xanomeline High Dose		Week 6	110.0	96.7	13.3
Xanomeline High Dose		Week 6	109.3	102.0	7.3
Xanomeline High Dose		Week 6	108.7	102.7	6.0
Xanomeline High Dose		Week 8	100.0	96.7	3.3
Xanomeline High Dose		Week 8	102.7	102.0	0.7
Xanomeline High Dose		Week 8	101.3	102.7	-1.3
Xanomeline High Dose			90.0	96.7
Xanomeline High Dose			98.7	102.0
Xanomeline High Dose			95.3	102.7
Placebo		Week 12	106.0	104.7	1.3
Placebo		Week 12	105.3	96.7	8.7
Placebo		Week 12	105.3	97.3	8.0
Placebo		Week 16	102.0	104.7	-2.7
Placebo		Week 16	100.0	96.7	3.3
Placebo		Week 16	102.7	97.3	5.3
Placebo		Week 2	90.0	104.7	-14.7
Placebo		Week 2	86.7	96.7	-10.0
Placebo		Week 2	86.0	97.3	-11.3
Placebo		Week 20	99.3	104.7	-5.3
Placebo		Week 20	93.3	96.7	-3.3
Placebo		Week 20	98.0	97.3	0.7
Placebo		Week 24	95.3	104.7	-9.3
Placebo		Week 24	86.7	96.7	-10.0
Placebo		Week 24	90.7	97.3	-6.7
Placebo		Week 26	86.7	104.7	-18.0
Placebo		Week 26	84.7	96.7	-12.0
Placebo		Week 26	81.3	97.3	-16.0
Placebo		Week 4	100.0	104.7	-4.7
Placebo		Week 4	97.3	96.7	0.7
Placebo		Week 4	96.7	97.3	-0.7
Placebo		Week 6	100.0	104.7	-4.7
Placebo		Week 6	92.7	96.7	-4.0
Placebo		Week 6	97.3	97.3	0.0
Placebo		Week 8	103.3	104.7	-1.3
Placebo		Week 8	100.7	96.7	4.0
Placebo		Week 8	100.0	97.3	2.7
Placebo			84.7	104.7
Placebo			85.3	96.7
Placebo			86.0	97.3
Placebo		Week 12	109.3	112.7	-3.3
Placebo		Week 12	108.0	118.7	-10.7
Placebo		Week 12	108.0	119.3	-11.3
Placebo		Week 16	113.3	112.7	0.7
Placebo		Week 16	118.7	118.7	0.0
Placebo		Week 16	114.7	119.3	-4.7
Placebo		Week 2	106.7	112.7	-6.0
Placebo		Week 2	103.0	118.7	-15.7
Placebo		Week 2	101.7	119.3	-17.7
Placebo		Week 20	109.3	112.7	-3.3
Placebo		Week 20	110.7	118.7	-8.0
Placebo		Week 20	111.3	119.3	-8.0
Placebo		Week 24	101.7	112.7	-11.0
Placebo		Week 24	100.0	118.7	-18.7
Placebo		Week 24	103.3	119.3	-16.0
Placebo		Week 26	93.3	112.7	-19.3
Placebo		Week 26	98.7	118.7	-20.0
Placebo		Week 26	96.7	119.3	-22.7
Placebo		Week 4	108.0	112.7	-4.7
Placebo		Week 4	110.7	118.7	-8.0
Placebo		Week 4	111.3	119.3	-8.0
Placebo		Week 6	106.0	112.7	-6.7
Placebo		Week 6	104.7	118.7	-14.0
Placebo		Week 6	102.7	119.3	-16.7
Placebo		Week 8	106.7	112.7	-6.0
Placebo		Week 8	107.3	118.7	-11.3
Placebo		Week 8	106.0	119.3	-13.3
Placebo			102.7	112.7
Placebo			102.7	118.7
Placebo			97.3	119.3
Placebo			95.3	112.7
Placebo			100.0	118.7
Placebo			97.3	119.3
Xanomeline High Dose		Week 2	110.0	124.0	-14.0
Xanomeline High Dose		Week 2	112.0	126.7	-14.7
Xanomeline High Dose		Week 2	112.7	124.7	-12.0
Xanomeline High Dose		Week 4	104.7	124.0	-19.3
Xanomeline High Dose		Week 4	106.7	126.7	-20.0
Xanomeline High Dose		Week 4	106.0	124.7	-18.7
Xanomeline High Dose		Week 6	119.3	124.0	-4.7
Xanomeline High Dose		Week 6	119.3	126.7	-7.3
Xanomeline High Dose		Week 6	117.3	124.7	-7.3
Xanomeline High Dose			124.0	124.0
Xanomeline High Dose			121.3	126.7
Xanomeline High Dose			120.7	124.7
Xanomeline High Dose			119.3	124.0
Xanomeline High Dose			122.0	126.7
Xanomeline High Dose			120.0	124.7
Xanomeline High Dose		Week 2	88.0	91.3	-3.3
Xanomeline High Dose		Week 2	87.3	96.7	-9.3
Xanomeline High Dose		Week 2	86.7	94.0	-7.3
Xanomeline High Dose			88.0	91.3
Xanomeline High Dose			94.0	96.7
Xanomeline High Dose			91.3	94.0
Xanomeline Low Dose		Week 2	93.3	89.3	4.0
Xanomeline Low Dose		Week 2	90.0	95.3	-5.3
Xanomeline Low Dose		Week 2	91.7	93.3	-1.7
Xanomeline Low Dose		Week 4	94.7	89.3	5.3
Xanomeline Low Dose		Week 4	94.7	95.3	-0.7
Xanomeline Low Dose		Week 4	94.0	93.3	0.7
Xanomeline Low Dose		Week 12	106.7	120.0	-13.3
Xanomeline Low Dose		Week 12	96.7	120.7	-24.0
Xanomeline Low Dose		Week 12	100.7	118.7	-18.0
Xanomeline Low Dose		Week 2	96.7	120.0	-23.3
Xanomeline Low Dose		Week 2	100.0	120.7	-20.7
Xanomeline Low Dose		Week 2	98.7	118.7	-20.0
Xanomeline Low Dose		Week 4	103.3	120.0	-16.7
Xanomeline Low Dose		Week 4	100.0	120.7	-20.7
Xanomeline Low Dose		Week 4	102.0	118.7	-16.7
Xanomeline Low Dose		Week 6	98.7	120.0	-21.3
Xanomeline Low Dose		Week 6	100.0	120.7	-20.7
Xanomeline Low Dose		Week 6	97.3	118.7	-21.3
Xanomeline Low Dose		Week 8	122.0	120.0	2.0
Xanomeline Low Dose		Week 8	118.7	120.7	-2.0
Xanomeline Low Dose		Week 8	118.7	118.7	0.0
Xanomeline Low Dose			101.3	120.0
Xanomeline Low Dose			100.0	120.7
Xanomeline Low Dose			98.0	118.7
Xanomeline Low Dose			86.7	120.0
Xanomeline Low Dose			91.3	120.7
Xanomeline Low Dose			89.3	118.7
Placebo		Week 12	102.0	114.0	-12.0
Placebo		Week 12	104.0	109.3	-5.3
Placebo		Week 12	103.3	111.3	-8.0
Placebo		Week 16	103.3	114.0	-10.7
Placebo		Week 16	100.7	109.3	-8.7
Placebo		Week 16	102.0	111.3	-9.3
Placebo		Week 2	105.3	114.0	-8.7
Placebo		Week 2	106.0	109.3	-3.3
Placebo		Week 2	106.7	111.3	-4.7
Placebo		Week 20	96.7	114.0	-17.3
Placebo		Week 20	98.0	109.3	-11.3
Placebo		Week 20	98.7	111.3	-12.7
Placebo		Week 24	103.3	114.0	-10.7
Placebo		Week 24	109.3	109.3	0.0
Placebo		Week 24	106.7	111.3	-4.7
Placebo		Week 26	106.7	114.0	-7.3
Placebo		Week 26	112.0	109.3	2.7
Placebo		Week 26	110.0	111.3	-1.3
Placebo		Week 4	109.3	114.0	-4.7
Placebo		Week 4	118.7	109.3	9.3
Placebo		Week 4	116.7	111.3	5.3
Placebo		Week 6	105.3	114.0	-8.7
Placebo		Week 6	106.7	109.3	-2.7
Placebo		Week 6	106.0	111.3	-5.3
Placebo		Week 8	102.7	114.0	-11.3
Placebo		Week 8	100.0	109.3	-9.3
Placebo		Week 8	100.0	111.3	-11.3
Placebo			110.0	114.0
Placebo			109.3	109.3
Placebo			110.0	111.3
Placebo			93.3	114.0
Placebo			102.7	109.3
Placebo			99.3	111.3
Xanomeline High Dose		Week 12	106.0	90.7	15.3
Xanomeline High Dose		Week 12	96.7	95.3	1.3
Xanomeline High Dose		Week 12	97.3	93.3	4.0
Xanomeline High Dose		Week 16	90.7	90.7	0.0
Xanomeline High Dose		Week 16	96.7	95.3	1.3
Xanomeline High Dose		Week 16	96.7	93.3	3.3
Xanomeline High Dose		Week 2	96.7	90.7	6.0
Xanomeline High Dose		Week 2	99.3	95.3	4.0
Xanomeline High Dose		Week 2	97.3	93.3	4.0
Xanomeline High Dose		Week 20	83.3	90.7	-7.3
Xanomeline High Dose		Week 20	88.0	95.3	-7.3
Xanomeline High Dose		Week 20	87.3	93.3	-6.0
Xanomeline High Dose		Week 24	86.7	90.7	-4.0
Xanomeline High Dose		Week 24	88.0	95.3	-7.3
Xanomeline High Dose		Week 24	86.7	93.3	-6.7
Xanomeline High Dose		Week 26	76.7	90.7	-14.0
Xanomeline High Dose		Week 26	84.0	95.3	-11.3
Xanomeline High Dose		Week 26	82.0	93.3	-11.3
Xanomeline High Dose		Week 4	83.3	90.7	-7.3
Xanomeline High Dose		Week 4	91.3	95.3	-4.0
Xanomeline High Dose		Week 4	94.7	93.3	1.3
Xanomeline High Dose		Week 6	86.0	90.7	-4.7
Xanomeline High Dose		Week 6	88.0	95.3	-7.3
Xanomeline High Dose		Week 6	90.0	93.3	-3.3
Xanomeline High Dose		Week 8	81.3	90.7	-9.3
Xanomeline High Dose		Week 8	90.0	95.3	-5.3
Xanomeline High Dose		Week 8	88.0	93.3	-5.3
Xanomeline High Dose			89.3	90.7
Xanomeline High Dose			91.3	95.3
Xanomeline High Dose			93.3	93.3
Xanomeline Low Dose		Week 12	95.3	106.7	-11.3
Xanomeline Low Dose		Week 12	96.0	106.7	-10.7
Xanomeline Low Dose		Week 12	99.3	106.0	-6.7
Xanomeline Low Dose		Week 16	93.3	106.7	-13.3
Xanomeline Low Dose		Week 16	100.7	106.7	-6.0
Xanomeline Low Dose		Week 16	97.3	106.0	-8.7
Xanomeline Low Dose		Week 2	102.0	106.7	-4.7
Xanomeline Low Dose		Week 2	102.0	106.7	-4.7
Xanomeline Low Dose		Week 2	101.3	106.0	-4.7
Xanomeline Low Dose		Week 20	83.3	106.7	-23.3
Xanomeline Low Dose		Week 20	96.7	106.7	-10.0
Xanomeline Low Dose		Week 20	93.3	106.0	-12.7
Xanomeline Low Dose		Week 24	101.3	106.7	-5.3
Xanomeline Low Dose		Week 24	102.0	106.7	-4.7
Xanomeline Low Dose		Week 24	100.0	106.0	-6.0
Xanomeline Low Dose		Week 26	96.0	106.7	-10.7
Xanomeline Low Dose		Week 26	98.0	106.7	-8.7
Xanomeline Low Dose		Week 26	97.3	106.0	-8.7
Xanomeline Low Dose		Week 4	87.3	106.7	-19.3
Xanomeline Low Dose		Week 4	92.0	106.7	-14.7
Xanomeline Low Dose		Week 4	90.0	106.0	-16.0
Xanomeline Low Dose		Week 6	95.3	106.7	-11.3
Xanomeline Low Dose		Week 6	102.7	106.7	-4.0
Xanomeline Low Dose		Week 6	100.7	106.0	-5.3
Xanomeline Low Dose		Week 8	96.7	106.7	-10.0
Xanomeline Low Dose		Week 8	102.7	106.7	-4.0
Xanomeline Low Dose		Week 8	100.7	106.0	-5.3
Xanomeline Low Dose			93.3	106.7
Xanomeline Low Dose			96.0	106.7
Xanomeline Low Dose			95.3	106.0
Xanomeline Low Dose			99.3	106.7
Xanomeline Low Dose			103.3	106.7
Xanomeline Low Dose			101.3	106.0
Xanomeline High Dose		Week 12	83.3	90.0	-6.7
Xanomeline High Dose		Week 12	89.3	93.3	-4.0
Xanomeline High Dose		Week 12	86.0	96.0	-10.0
Xanomeline High Dose		Week 16	80.0	90.0	-10.0
Xanomeline High Dose		Week 16	83.3	93.3	-10.0
Xanomeline High Dose		Week 16	81.3	96.0	-14.7
Xanomeline High Dose		Week 2	90.0	90.0	0.0
Xanomeline High Dose		Week 2	97.3	93.3	4.0
Xanomeline High Dose		Week 2	95.3	96.0	-0.7
Xanomeline High Dose		Week 20	83.3	90.0	-6.7
Xanomeline High Dose		Week 20	82.0	93.3	-11.3
Xanomeline High Dose		Week 20	84.0	96.0	-12.0
Xanomeline High Dose		Week 24	83.3	90.0	-6.7
Xanomeline High Dose		Week 24	101.3	93.3	8.0
Xanomeline High Dose		Week 24	100.7	96.0	4.7
Xanomeline High Dose		Week 26	90.0	90.0	0.0
Xanomeline High Dose		Week 26	93.3	93.3	0.0
Xanomeline High Dose		Week 26	91.3	96.0	-4.7
Xanomeline High Dose		Week 4	88.7	90.0	-1.3
Xanomeline High Dose		Week 4	89.3	93.3	-4.0
Xanomeline High Dose		Week 4	90.0	96.0	-6.0
Xanomeline High Dose		Week 6	92.0	90.0	2.0
Xanomeline High Dose		Week 6	88.7	93.3	-4.7
Xanomeline High Dose		Week 6	91.3	96.0	-4.7
Xanomeline High Dose		Week 8	89.3	90.0	-0.7
Xanomeline High Dose		Week 8	95.3	93.3	2.0
Xanomeline High Dose		Week 8	92.0	96.0	-4.0
Xanomeline High Dose			87.3	90.0
Xanomeline High Dose			99.3	93.3
Xanomeline High Dose			94.0	96.0
Xanomeline High Dose			91.3	90.0
Xanomeline High Dose			99.3	93.3
Xanomeline High Dose			97.3	96.0
Placebo		Week 12	87.3	103.3	-16.0
Placebo		Week 12	84.0	108.0	-24.0
Placebo		Week 12	88.3	106.0	-17.7
Placebo		Week 16	98.7	103.3	-4.7
Placebo		Week 16	96.7	108.0	-11.3
Placebo		Week 16	100.0	106.0	-6.0
Placebo		Week 2	86.7	103.3	-16.7
Placebo		Week 2	86.0	108.0	-22.0
Placebo		Week 2	86.0	106.0	-20.0
Placebo		Week 4	94.0	103.3	-9.3
Placebo		Week 4	90.7	108.0	-17.3
Placebo		Week 4	93.3	106.0	-12.7
Placebo		Week 6	93.3	103.3	-10.0
Placebo		Week 6	84.0	108.0	-24.0
Placebo		Week 6	88.7	106.0	-17.3
Placebo		Week 8	88.7	103.3	-14.7
Placebo		Week 8	88.7	108.0	-19.3
Placebo		Week 8	90.7	106.0	-15.3
Placebo			105.3	103.3
Placebo			96.7	108.0
Placebo			99.3	106.0
Placebo			94.7	103.3
Placebo			94.0	108.0
Placebo			96.0	106.0
Xanomeline Low Dose		Week 2	113.3	109.3	4.0
Xanomeline Low Dose		Week 2	116.0	113.3	2.7
Xanomeline Low Dose		Week 2	114.0	111.3	2.7
Placebo		Week 2	105.3	94.0	11.3
Placebo		Week 2	106.0	98.7	7.3
Placebo		Week 2	108.0	96.7	11.3
Placebo		Week 4	103.3	94.0	9.3
Placebo		Week 4	112.0	98.7	13.3
Placebo		Week 4	109.3	96.7	12.7
Placebo		Week 6	111.3	94.0	17.3
Placebo		Week 6	113.3	98.7	14.7
Placebo		Week 6	110.0	96.7	13.3
Placebo			100.0	94.0
Placebo			98.0	98.7
Placebo			99.3	96.7
Placebo			90.0	94.0
Placebo			90.7	98.7
Placebo			91.3	96.7
Xanomeline High Dose		Week 2	92.7	96.7	-4.0
Xanomeline High Dose		Week 2	90.7	110.7	-20.0
Xanomeline High Dose		Week 2	94.0	104.7	-10.7
Xanomeline High Dose		Week 4	85.3	96.7	-11.3
Xanomeline High Dose		Week 4	94.0	110.7	-16.7
Xanomeline High Dose		Week 4	86.7	104.7	-18.0
Xanomeline High Dose		Week 6	104.7	96.7	8.0
Xanomeline High Dose		Week 6	104.0	110.7	-6.7
Xanomeline High Dose		Week 6	102.0	104.7	-2.7
Xanomeline High Dose		Week 8	100.7	96.7	4.0
Xanomeline High Dose		Week 8	105.3	110.7	-5.3
Xanomeline High Dose		Week 8	104.7	104.7	0.0
Xanomeline High Dose			106.0	96.7
Xanomeline High Dose			106.7	110.7
Xanomeline High Dose			106.7	104.7
Xanomeline High Dose			103.3	96.7
Xanomeline High Dose			105.3	110.7
Xanomeline High Dose			105.3	104.7
Xanomeline Low Dose		Week 2	96.7	100.7	-4.0
Xanomeline Low Dose		Week 2	109.3	104.7	4.7
Xanomeline Low Dose		Week 2	106.0	102.7	3.3
Xanomeline Low Dose		Week 4	110.7	100.7	10.0
Xanomeline Low Dose		Week 4	110.7	104.7	6.0
Xanomeline Low Dose		Week 4	110.0	102.7	7.3
Xanomeline Low Dose		Week 6	97.3	100.7	-3.3
Xanomeline Low Dose		Week 6	93.3	104.7	-11.3
Xanomeline Low Dose		Week 6	94.7	102.7	-8.0
Xanomeline Low Dose		Week 8	113.3	100.7	12.7
Xanomeline Low Dose		Week 8	117.3	104.7	12.7
Xanomeline Low Dose		Week 8	116.0	102.7	13.3
Xanomeline Low Dose			104.7	100.7
Xanomeline Low Dose			104.0	104.7
Xanomeline Low Dose			106.0	102.7
Xanomeline Low Dose			106.7	100.7
Xanomeline Low Dose			110.7	104.7
Xanomeline Low Dose			111.3	102.7
Placebo		Week 2	80.7	93.3	-12.7
Placebo		Week 2	87.3	97.3	-10.0
Placebo		Week 2	84.0	95.3	-11.3
Placebo		Week 4	94.7	93.3	1.3
Placebo		Week 4	94.0	97.3	-3.3
Placebo		Week 4	94.7	95.3	-0.7
Placebo			79.3	93.3
Placebo			80.7	97.3
Placebo			84.0	95.3
Placebo		Week 12	118.7	115.3	3.3
Placebo		Week 12	120.0	115.3	4.7
Placebo		Week 12	119.3	114.0	5.3
Placebo		Week 16	118.7	115.3	3.3
Placebo		Week 16	120.0	115.3	4.7
Placebo		Week 16	117.3	114.0	3.3
Placebo		Week 2	114.7	115.3	-0.7
Placebo		Week 2	115.3	115.3	0.0
Placebo		Week 2	114.0	114.0	0.0
Placebo		Week 4	109.3	115.3	-6.0
Placebo		Week 4	110.0	115.3	-5.3
Placebo		Week 4	109.3	114.0	-4.7
Placebo		Week 6	116.0	115.3	0.7
Placebo		Week 6	108.0	115.3	-7.3
Placebo		Week 6	111.3	114.0	-2.7
Placebo		Week 8	117.3	115.3	2.0
Placebo		Week 8	116.7	115.3	1.3
Placebo		Week 8	116.7	114.0	2.7
Placebo			118.7	115.3
Placebo			114.0	115.3
Placebo			114.7	114.0
Placebo			115.3	115.3
Placebo			114.0	115.3
Placebo			114.7	114.0
Xanomeline High Dose		Week 12	80.0	105.3	-25.3
Xanomeline High Dose		Week 12	90.0	103.3	-13.3
Xanomeline High Dose		Week 12	88.0	102.0	-14.0
Xanomeline High Dose		Week 16	104.7	105.3	-0.7
Xanomeline High Dose		Week 16	100.0	103.3	-3.3
Xanomeline High Dose		Week 16	102.0	102.0	0.0
Xanomeline High Dose		Week 2	103.3	105.3	-2.0
Xanomeline High Dose		Week 2	100.0	103.3	-3.3
Xanomeline High Dose		Week 2	100.0	102.0	-2.0
Xanomeline High Dose		Week 20	104.7	105.3	-0.7
Xanomeline High Dose		Week 20	101.3	103.3	-2.0
Xanomeline High Dose		Week 20	100.7	102.0	-1.3
Xanomeline High Dose		Week 24	100.0	105.3	-5.3
Xanomeline High Dose		Week 24	95.3	103.3	-8.0
Xanomeline High Dose		Week 24	97.3	102.0	-4.7
Xanomeline High Dose		Week 26	93.3	105.3	-12.0
Xanomeline High Dose		Week 26	96.0	103.3	-7.3
Xanomeline High Dose		Week 26	94.0	102.0	-8.0
Xanomeline High Dose		Week 4	102.0	105.3	-3.3
Xanomeline High Dose		Week 4	100.0	103.3	-3.3
Xanomeline High Dose		Week 4	99.3	102.0	-2.7
Xanomeline High Dose		Week 6	105.3	105.3	0.0
Xanomeline High Dose		Week 6	96.7	103.3	-6.7
Xanomeline High Dose		Week 6	101.3	102.0	-0.7
Xanomeline High Dose		Week 8	105.3	105.3	0.0
Xanomeline High Dose		Week 8	106.0	103.3	2.7
Xanomeline High Dose		Week 8	108.0	102.0	6.0
Xanomeline High Dose			92.0	105.3
Xanomeline High Dose			95.3	103.3
Xanomeline High Dose			93.3	102.0
Xanomeline High Dose			102.0	105.3
Xanomeline High Dose			103.3	103.3
Xanomeline High Dose			102.7	102.0
Xanomeline Low Dose		Week 12	105.3	103.3	2.0
Xanomeline Low Dose		Week 12	110.7	104.0	6.7
Xanomeline Low Dose		Week 12	108.7	100.7	8.0
Xanomeline Low Dose		Week 16	96.7	103.3	-6.7
Xanomeline Low Dose		Week 16	104.0	104.0	0.0
Xanomeline Low Dose		Week 16	102.0	100.7	1.3
Xanomeline Low Dose		Week 2	94.7	103.3	-8.7
Xanomeline Low Dose		Week 2	98.7	104.0	-5.3
Xanomeline Low Dose		Week 2	96.7	100.7	-4.0
Xanomeline Low Dose		Week 20	93.3	103.3	-10.0
Xanomeline Low Dose		Week 20	102.0	104.0	-2.0
Xanomeline Low Dose		Week 20	100.0	100.7	-0.7
Xanomeline Low Dose		Week 4	101.3	103.3	-2.0
Xanomeline Low Dose		Week 4	104.0	104.0	0.0
Xanomeline Low Dose		Week 4	104.0	100.7	3.3
Xanomeline Low Dose		Week 6	104.7	103.3	1.3
Xanomeline Low Dose		Week 6	108.7	104.0	4.7
Xanomeline Low Dose		Week 6	106.7	100.7	6.0
Xanomeline Low Dose		Week 8	106.7	103.3	3.3
Xanomeline Low Dose		Week 8	116.7	104.0	12.7
Xanomeline Low Dose		Week 8	114.0	100.7	13.3
Xanomeline Low Dose			104.0	103.3
Xanomeline Low Dose			103.3	104.0
Xanomeline Low Dose			102.7	100.7
Xanomeline Low Dose			97.3	103.3
Xanomeline Low Dose			108.7	104.0
Xanomeline Low Dose			106.7	100.7
Placebo		Week 12	83.3	109.3	-26.0
Placebo		Week 12	80.0	104.7	-24.7
Placebo		Week 12	82.7	108.0	-25.3
Placebo		Week 16	94.7	109.3	-14.7
Placebo		Week 16	88.7	104.7	-16.0
Placebo		Week 16	88.7	108.0	-19.3
Placebo		Week 2	90.0	109.3	-19.3
Placebo		Week 2	94.0	104.7	-10.7
Placebo		Week 2	90.7	108.0	-17.3
Placebo		Week 20	96.7	109.3	-12.7
Placebo		Week 20	96.7	104.7	-8.0
Placebo		Week 20	96.0	108.0	-12.0
Placebo		Week 24	96.7	109.3	-12.7
Placebo		Week 24	100.7	104.7	-4.0
Placebo		Week 24	98.7	108.0	-9.3
Placebo		Week 26	95.3	109.3	-14.0
Placebo		Week 26	98.0	104.7	-6.7
Placebo		Week 26	97.3	108.0	-10.7
Placebo		Week 4	81.3	109.3	-28.0
Placebo		Week 4	80.0	104.7	-24.7
Placebo		Week 4	79.3	108.0	-28.7
Placebo		Week 6	90.0	109.3	-19.3
Placebo		Week 6	90.7	104.7	-14.0
Placebo		Week 6	92.7	108.0	-15.3
Placebo		Week 8	99.3	109.3	-10.0
Placebo		Week 8	95.3	104.7	-9.3
Placebo		Week 8	96.0	108.0	-12.0
Placebo			91.3	109.3
Placebo			92.7	104.7
Placebo			94.7	108.0
Placebo			84.0	109.3
Placebo			90.0	104.7
Placebo			87.3	108.0
Xanomeline Low Dose		Week 12	110.0	120.0	-10.0
Xanomeline Low Dose		Week 12	114.7	118.7	-4.0
Xanomeline Low Dose		Week 12	112.0	120.0	-8.0
Xanomeline Low Dose		Week 16	96.7	120.0	-23.3
Xanomeline Low Dose		Week 16	102.0	118.7	-16.7
Xanomeline Low Dose		Week 16	100.7	120.0	-19.3
Xanomeline Low Dose		Week 2	103.3	120.0	-16.7
Xanomeline Low Dose		Week 2	110.0	118.7	-8.7
Xanomeline Low Dose		Week 2	108.0	120.0	-12.0
Xanomeline Low Dose		Week 4	106.7	120.0	-13.3
Xanomeline Low Dose		Week 4	112.0	118.7	-6.7
Xanomeline Low Dose		Week 4	111.3	120.0	-8.7
Xanomeline Low Dose		Week 6	119.3	120.0	-0.7
Xanomeline Low Dose		Week 6	120.0	118.7	1.3
Xanomeline Low Dose		Week 6	118.7	120.0	-1.3
Xanomeline Low Dose		Week 8	101.3	120.0	-18.7
Xanomeline Low Dose		Week 8	104.0	118.7	-14.7
Xanomeline Low Dose		Week 8	106.7	120.0	-13.3
Xanomeline Low Dose			116.7	120.0
Xanomeline Low Dose			115.3	118.7
Xanomeline Low Dose			113.3	120.0
Xanomeline Low Dose			110.0	120.0
Xanomeline Low Dose			116.0	118.7
Xanomeline Low Dose			112.7	120.0
Xanomeline High Dose		Week 12	106.0	122.0	-16.0
Xanomeline High Dose		Week 12	110.0	120.7	-10.7
Xanomeline High Dose		Week 12	110.0	120.0	-10.0
Xanomeline High Dose		Week 16	103.3	122.0	-18.7
Xanomeline High Dose		Week 16	102.7	120.7	-18.0
Xanomeline High Dose		Week 16	99.3	120.0	-20.7
Xanomeline High Dose		Week 2	79.3	122.0	-42.7
Xanomeline High Dose		Week 2	84.7	120.7	-36.0
Xanomeline High Dose		Week 2	82.7	120.0	-37.3
Xanomeline High Dose		Week 20	111.3	122.0	-10.7
Xanomeline High Dose		Week 20	107.3	120.7	-13.3
Xanomeline High Dose		Week 20	110.0	120.0	-10.0
Xanomeline High Dose		Week 24	100.7	122.0	-21.3
Xanomeline High Dose		Week 24	108.0	120.7	-12.7
Xanomeline High Dose		Week 24	105.3	120.0	-14.7
Xanomeline High Dose		Week 26	94.0	122.0	-28.0
Xanomeline High Dose		Week 26	96.7	120.7	-24.0
Xanomeline High Dose		Week 26	97.3	120.0	-22.7
Xanomeline High Dose		Week 4	84.0	122.0	-38.0
Xanomeline High Dose		Week 4	86.0	120.7	-34.7
Xanomeline High Dose		Week 4	84.0	120.0	-36.0
Xanomeline High Dose		Week 6	101.3	122.0	-20.7
Xanomeline High Dose		Week 6	96.7	120.7	-24.0
Xanomeline High Dose		Week 6	98.0	120.0	-22.0
Xanomeline High Dose		Week 8	107.3	122.0	-14.7
Xanomeline High Dose		Week 8	105.3	120.7	-15.3
Xanomeline High Dose		Week 8	107.3	120.0	-12.7
Xanomeline High Dose			88.0	122.0
Xanomeline High Dose			92.7	120.7
Xanomeline High Dose			92.0	120.0
Xanomeline High Dose			92.7	122.0
Xanomeline High Dose			97.3	120.7
Xanomeline High Dose			95.3	120.0
Xanomeline High Dose		Week 2	104.0	104.7	-0.7
Xanomeline High Dose		Week 2	92.0	94.0	-2.0
Xanomeline High Dose		Week 2	97.3	102.7	-5.3
Xanomeline High Dose			97.3	104.7
Xanomeline High Dose			90.7	94.0
Xanomeline High Dose			91.3	102.7
Placebo		Week 12	93.3	98.0	-4.7
Placebo		Week 12	88.7	89.3	-0.7
Placebo		Week 12	88.7	88.7	0.0
Placebo		Week 16	90.7	98.0	-7.3
Placebo		Week 16	92.0	89.3	2.7
Placebo		Week 16	89.3	88.7	0.7
Placebo		Week 2	87.3	98.0	-10.7
Placebo		Week 2	80.7	89.3	-8.7
Placebo		Week 2	80.7	88.7	-8.0
Placebo		Week 20	95.3	98.0	-2.7
Placebo		Week 20	86.0	89.3	-3.3
Placebo		Week 20	83.3	88.7	-5.3
Placebo		Week 24	103.3	98.0	5.3
Placebo		Week 24	100.0	89.3	10.7
Placebo		Week 24	92.7	88.7	4.0
Placebo		Week 26	99.3	98.0	1.3
Placebo		Week 26	86.0	89.3	-3.3
Placebo		Week 26	78.7	88.7	-10.0
Placebo		Week 4	96.0	98.0	-2.0
Placebo		Week 4	84.7	89.3	-4.7
Placebo		Week 4	86.7	88.7	-2.0
Placebo		Week 6	101.3	98.0	3.3
Placebo		Week 6	92.7	89.3	3.3
Placebo		Week 6	90.7	88.7	2.0
Placebo		Week 8	101.3	98.0	3.3
Placebo		Week 8	88.0	89.3	-1.3
Placebo		Week 8	90.0	88.7	1.3
Placebo			81.3	98.0
Placebo			82.7	89.3
Placebo			83.3	88.7
Placebo			87.3	98.0
Placebo			77.3	89.3
Placebo			76.7	88.7
Xanomeline Low Dose		Week 2	100.0	105.3	-5.3
Xanomeline Low Dose		Week 2	102.0	94.7	7.3
Xanomeline Low Dose		Week 2	102.7	98.0	4.7
Xanomeline Low Dose		Week 4	109.3	105.3	4.0
Xanomeline Low Dose		Week 4	98.0	94.7	3.3
Xanomeline Low Dose		Week 4	101.3	98.0	3.3
Xanomeline Low Dose		Week 6	106.0	105.3	0.7
Xanomeline Low Dose		Week 6	97.3	94.7	2.7
Xanomeline Low Dose		Week 6	104.0	98.0	6.0
Xanomeline Low Dose		Week 8	101.3	105.3	-4.0
Xanomeline Low Dose		Week 8	94.0	94.7	-0.7
Xanomeline Low Dose		Week 8	91.3	98.0	-6.7
Xanomeline Low Dose			100.0	105.3
Xanomeline Low Dose			100.7	94.7
Xanomeline Low Dose			101.3	98.0
Xanomeline Low Dose			93.3	105.3
Xanomeline Low Dose			86.7	94.7
Xanomeline Low Dose			80.0	98.0
Xanomeline Low Dose		Week 12	90.0	83.3	6.7
Xanomeline Low Dose		Week 12	93.3	90.0	3.3
Xanomeline Low Dose		Week 12	90.0	93.3	-3.3
Xanomeline Low Dose		Week 16	83.3	83.3	0.0
Xanomeline Low Dose		Week 16	86.7	90.0	-3.3
Xanomeline Low Dose		Week 16	90.0	93.3	-3.3
Xanomeline Low Dose		Week 2	90.0	83.3	6.7
Xanomeline Low Dose		Week 2	86.7	90.0	-3.3
Xanomeline Low Dose		Week 2	93.3	93.3	0.0
Xanomeline Low Dose		Week 20	90.7	83.3	7.3
Xanomeline Low Dose		Week 20	90.0	90.0	0.0
Xanomeline Low Dose		Week 20	96.7	93.3	3.3
Xanomeline Low Dose		Week 24	80.0	83.3	-3.3
Xanomeline Low Dose		Week 24	80.0	90.0	-10.0
Xanomeline Low Dose		Week 24	96.7	93.3	3.3
Xanomeline Low Dose		Week 26	83.3	83.3	0.0
Xanomeline Low Dose		Week 26	86.7	90.0	-3.3
Xanomeline Low Dose		Week 26	88.7	93.3	-4.7
Xanomeline Low Dose		Week 4	90.0	83.3	6.7
Xanomeline Low Dose		Week 4	86.7	90.0	-3.3
Xanomeline Low Dose		Week 4	80.0	93.3	-13.3
Xanomeline Low Dose		Week 6	80.0	83.3	-3.3
Xanomeline Low Dose		Week 6	83.3	90.0	-6.7
Xanomeline Low Dose		Week 6	93.3	93.3	0.0
Xanomeline Low Dose		Week 8	90.0	83.3	6.7
Xanomeline Low Dose		Week 8	83.3	90.0	-6.7
Xanomeline Low Dose		Week 8	83.3	93.3	-10.0
Xanomeline Low Dose			80.0	83.3
Xanomeline Low Dose			83.3	90.0
Xanomeline Low Dose			93.3	93.3
Xanomeline Low Dose			90.0	83.3
Xanomeline Low Dose			96.7	90.0
Xanomeline Low Dose			100.0	93.3
Xanomeline Low Dose		Week 12	106.7	106.7	0.0
Xanomeline Low Dose		Week 12	110.0	110.0	0.0
Xanomeline Low Dose		Week 12	110.0	116.7	-6.7
Xanomeline Low Dose		Week 16	103.3	106.7	-3.3
Xanomeline Low Dose		Week 16	100.0	110.0	-10.0
Xanomeline Low Dose		Week 16	106.7	116.7	-10.0
Xanomeline Low Dose		Week 2	110.0	106.7	3.3
Xanomeline Low Dose		Week 2	106.7	110.0	-3.3
Xanomeline Low Dose		Week 2	110.0	116.7	-6.7
Xanomeline Low Dose		Week 20	94.0	106.7	-12.7
Xanomeline Low Dose		Week 20	93.3	110.0	-16.7
Xanomeline Low Dose		Week 20	93.3	116.7	-23.3
Xanomeline Low Dose		Week 24	110.0	106.7	3.3
Xanomeline Low Dose		Week 24	110.0	110.0	0.0
Xanomeline Low Dose		Week 24	111.7	116.7	-5.0
Xanomeline Low Dose		Week 26	106.7	106.7	0.0
Xanomeline Low Dose		Week 26	110.0	110.0	0.0
Xanomeline Low Dose		Week 26	110.0	116.7	-6.7
Xanomeline Low Dose		Week 4	120.0	106.7	13.3
Xanomeline Low Dose		Week 4	116.7	110.0	6.7
Xanomeline Low Dose		Week 4	116.7	116.7	0.0
Xanomeline Low Dose		Week 6	111.3	106.7	4.7
Xanomeline Low Dose		Week 6	110.0	110.0	0.0
Xanomeline Low Dose		Week 6	110.0	116.7	-6.7
Xanomeline Low Dose		Week 8	106.7	106.7	0.0
Xanomeline Low Dose		Week 8	106.7	110.0	-3.3
Xanomeline Low Dose		Week 8	110.0	116.7	-6.7
Xanomeline Low Dose			83.3	106.7
Xanomeline Low Dose			93.3	110.0
Xanomeline Low Dose			90.0	116.7
Xanomeline High Dose		Week 12	90.0	83.3	6.7
Xanomeline High Dose		Week 12	83.3	83.3	0.0
Xanomeline High Dose		Week 12	76.7	83.3	-6.7
Xanomeline High Dose		Week 16	76.7	83.3	-6.7
Xanomeline High Dose		Week 16	80.0	83.3	-3.3
Xanomeline High Dose		Week 16	83.3	83.3	0.0
Xanomeline High Dose		Week 2	90.0	83.3	6.7
Xanomeline High Dose		Week 2	93.3	83.3	10.0
Xanomeline High Dose		Week 2	93.3	83.3	10.0
Xanomeline High Dose		Week 20	80.0	83.3	-3.3
Xanomeline High Dose		Week 20	76.7	83.3	-6.7
Xanomeline High Dose		Week 20	73.3	83.3	-10.0
Xanomeline High Dose		Week 24	90.0	83.3	6.7
Xanomeline High Dose		Week 24	70.0	83.3	-13.3
Xanomeline High Dose		Week 24	63.3	83.3	-20.0
Xanomeline High Dose		Week 26	70.0	83.3	-13.3
Xanomeline High Dose		Week 26	70.0	83.3	-13.3
Xanomeline High Dose		Week 26	66.7	83.3	-16.7
Xanomeline High Dose		Week 4	96.7	83.3	13.3
Xanomeline High Dose		Week 4	90.0	83.3	6.7
Xanomeline High Dose		Week 4	93.3	83.3	10.0
Xanomeline High Dose		Week 6	90.0	83.3	6.7
Xanomeline High Dose		Week 6	83.3	83.3	0.0
Xanomeline High Dose		Week 6	83.3	83.3	0.0
Xanomeline High Dose		Week 8	83.3	83.3	0.0
Xanomeline High Dose		Week 8	86.7	83.3	3.3
Xanomeline High Dose		Week 8	83.3	83.3	0.0
Xanomeline High Dose			83.3	83.3
Xanomeline High Dose			90.0	83.3
Xanomeline High Dose			80.0	83.3
Xanomeline High Dose			86.7	83.3
Xanomeline High Dose			93.3	83.3
Xanomeline High Dose			93.3	83.3
Xanomeline High Dose		Week 2	84.7	87.3	-2.7
Xanomeline High Dose		Week 2	82.0	80.0	2.0
Xanomeline High Dose		Week 2	84.0	93.3	-9.3
Xanomeline High Dose		Week 4	80.7	87.3	-6.7
Xanomeline High Dose		Week 4	73.3	80.0	-6.7
Xanomeline High Dose		Week 4	76.7	93.3	-16.7
Xanomeline High Dose			82.7	87.3
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			84.0	93.3
Xanomeline High Dose			80.0	87.3
Xanomeline High Dose			76.7	80.0
Xanomeline High Dose			70.0	93.3
Placebo		Week 12	93.3	86.7	6.7
Placebo		Week 12	100.0	83.3	16.7
Placebo		Week 12	96.7	83.3	13.3
Placebo		Week 16	113.3	86.7	26.7
Placebo		Week 16	106.7	83.3	23.3
Placebo		Week 16	106.7	83.3	23.3
Placebo		Week 2	86.7	86.7	0.0
Placebo		Week 2	100.0	83.3	16.7
Placebo		Week 2	103.3	83.3	20.0
Placebo		Week 20	86.7	86.7	0.0
Placebo		Week 20	80.0	83.3	-3.3
Placebo		Week 20	96.7	83.3	13.3
Placebo		Week 24	83.3	86.7	-3.3
Placebo		Week 24	93.3	83.3	10.0
Placebo		Week 24	96.7	83.3	13.3
Placebo		Week 26	76.7	86.7	-10.0
Placebo		Week 26	96.7	83.3	13.3
Placebo		Week 26	76.7	83.3	-6.7
Placebo		Week 4	90.0	86.7	3.3
Placebo		Week 4	76.7	83.3	-6.7
Placebo		Week 4	80.0	83.3	-3.3
Placebo		Week 6	90.0	86.7	3.3
Placebo		Week 6	110.0	83.3	26.7
Placebo		Week 6	96.7	83.3	13.3
Placebo		Week 8	90.0	86.7	3.3
Placebo		Week 8	86.7	83.3	3.3
Placebo		Week 8	93.3	83.3	10.0
Placebo			90.0	86.7
Placebo			96.7	83.3
Placebo			70.0	83.3
Placebo			86.7	86.7
Placebo			110.0	83.3
Placebo			92.0	83.3
Xanomeline High Dose		Week 12	73.3	86.7	-13.3
Xanomeline High Dose		Week 12	76.7	83.3	-6.7
Xanomeline High Dose		Week 12	76.7	96.7	-20.0
Xanomeline High Dose		Week 16	103.3	86.7	16.7
Xanomeline High Dose		Week 16	103.3	83.3	20.0
Xanomeline High Dose		Week 16	100.0	96.7	3.3
Xanomeline High Dose		Week 2	80.0	86.7	-6.7
Xanomeline High Dose		Week 2	80.0	83.3	-3.3
Xanomeline High Dose		Week 2	80.0	96.7	-16.7
Xanomeline High Dose		Week 20	86.7	86.7	0.0
Xanomeline High Dose		Week 20	86.7	83.3	3.3
Xanomeline High Dose		Week 20	88.0	96.7	-8.7
Xanomeline High Dose		Week 24	90.0	86.7	3.3
Xanomeline High Dose		Week 24	93.3	83.3	10.0
Xanomeline High Dose		Week 24	90.0	96.7	-6.7
Xanomeline High Dose		Week 26	76.7	86.7	-10.0
Xanomeline High Dose		Week 26	86.7	83.3	3.3
Xanomeline High Dose		Week 26	83.3	96.7	-13.3
Xanomeline High Dose		Week 4	96.7	86.7	10.0
Xanomeline High Dose		Week 4	90.0	83.3	6.7
Xanomeline High Dose		Week 4	90.0	96.7	-6.7
Xanomeline High Dose		Week 6	80.0	86.7	-6.7
Xanomeline High Dose		Week 6	73.3	83.3	-10.0
Xanomeline High Dose		Week 6	70.0	96.7	-26.7
Xanomeline High Dose		Week 8	90.0	86.7	3.3
Xanomeline High Dose		Week 8	90.0	83.3	6.7
Xanomeline High Dose		Week 8	80.0	96.7	-16.7
Xanomeline High Dose			96.7	86.7
Xanomeline High Dose			86.7	83.3
Xanomeline High Dose			90.0	96.7
Xanomeline High Dose			92.7	86.7
Xanomeline High Dose			98.7	83.3
Xanomeline High Dose			93.3	96.7
Placebo		Week 12	76.7	70.0	6.7
Placebo		Week 12	76.0	67.3	8.7
Placebo		Week 12	70.0	62.7	7.3
Placebo		Week 16	63.3	70.0	-6.7
Placebo		Week 16	60.0	67.3	-7.3
Placebo		Week 16	58.7	62.7	-4.0
Placebo		Week 2	76.7	70.0	6.7
Placebo		Week 2	80.0	67.3	12.7
Placebo		Week 2	73.3	62.7	10.7
Placebo		Week 20	70.0	70.0	0.0
Placebo		Week 20	70.0	67.3	2.7
Placebo		Week 20	66.7	62.7	4.0
Placebo		Week 24	73.3	70.0	3.3
Placebo		Week 24	70.0	67.3	2.7
Placebo		Week 24	73.3	62.7	10.7
Placebo		Week 26	73.3	70.0	3.3
Placebo		Week 26	63.3	67.3	-4.0
Placebo		Week 26	73.3	62.7	10.7
Placebo		Week 4	73.3	70.0	3.3
Placebo		Week 4	70.0	67.3	2.7
Placebo		Week 4	68.0	62.7	5.3
Placebo		Week 6	73.3	70.0	3.3
Placebo		Week 6	66.7	67.3	-0.7
Placebo		Week 6	68.0	62.7	5.3
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	63.3	67.3	-4.0
Placebo		Week 8	70.0	62.7	7.3
Placebo			73.3	70.0
Placebo			67.3	67.3
Placebo			73.3	62.7
Placebo			77.3	70.0
Placebo			73.3	67.3
Placebo			66.7	62.7
Placebo		Week 12	96.7	76.7	20.0
Placebo		Week 12	86.7	76.7	10.0
Placebo		Week 12	90.7	73.3	17.3
Placebo		Week 16	86.7	76.7	10.0
Placebo		Week 16	86.7	76.7	10.0
Placebo		Week 16	93.3	73.3	20.0
Placebo		Week 2	100.0	76.7	23.3
Placebo		Week 2	93.3	76.7	16.7
Placebo		Week 2	90.0	73.3	16.7
Placebo		Week 20	90.0	76.7	13.3
Placebo		Week 20	90.0	76.7	13.3
Placebo		Week 20	89.3	73.3	16.0
Placebo		Week 24	93.3	76.7	16.7
Placebo		Week 24	93.3	76.7	16.7
Placebo		Week 24	86.7	73.3	13.3
Placebo		Week 26	85.0	76.7	8.3
Placebo		Week 26	86.7	76.7	10.0
Placebo		Week 26	86.7	73.3	13.3
Placebo		Week 4	100.0	76.7	23.3
Placebo		Week 4	100.0	76.7	23.3
Placebo		Week 4	100.0	73.3	26.7
Placebo		Week 6	83.3	76.7	6.7
Placebo		Week 6	93.3	76.7	16.7
Placebo		Week 6	90.0	73.3	16.7
Placebo		Week 8	83.3	76.7	6.7
Placebo		Week 8	93.3	76.7	16.7
Placebo		Week 8	93.3	73.3	20.0
Placebo			86.7	76.7
Placebo			87.3	76.7
Placebo			84.0	73.3
Xanomeline Low Dose		Week 12	106.7	86.7	20.0
Xanomeline Low Dose		Week 12	103.3	86.7	16.7
Xanomeline Low Dose		Week 12	103.3	86.7	16.7
Xanomeline Low Dose		Week 2	90.0	86.7	3.3
Xanomeline Low Dose		Week 2	96.7	86.7	10.0
Xanomeline Low Dose		Week 2	96.7	86.7	10.0
Xanomeline Low Dose		Week 4	90.0	86.7	3.3
Xanomeline Low Dose		Week 4	93.3	86.7	6.7
Xanomeline Low Dose		Week 4	96.7	86.7	10.0
Xanomeline Low Dose		Week 6	98.3	86.7	11.7
Xanomeline Low Dose		Week 6	100.0	86.7	13.3
Xanomeline Low Dose		Week 6	100.0	86.7	13.3
Xanomeline Low Dose		Week 8	101.7	86.7	15.0
Xanomeline Low Dose		Week 8	103.3	86.7	16.7
Xanomeline Low Dose		Week 8	93.3	86.7	6.7
Xanomeline Low Dose			90.0	86.7
Xanomeline Low Dose			90.0	86.7
Xanomeline Low Dose			86.7	86.7
Xanomeline Low Dose			98.3	86.7
Xanomeline Low Dose			100.0	86.7
Xanomeline Low Dose			101.7	86.7
Placebo		Week 12	96.0	94.7	1.3
Placebo		Week 12	98.7	100.0	-1.3
Placebo		Week 12	94.7	98.0	-3.3
Placebo		Week 16	104.7	94.7	10.0
Placebo		Week 16	98.7	100.0	-1.3
Placebo		Week 16	98.0	98.0	0.0
Placebo		Week 2	106.7	94.7	12.0
Placebo		Week 2	103.3	100.0	3.3
Placebo		Week 2	100.0	98.0	2.0
Placebo		Week 20	104.7	94.7	10.0
Placebo		Week 20	96.0	100.0	-4.0
Placebo		Week 20	92.0	98.0	-6.0
Placebo		Week 24	104.0	94.7	9.3
Placebo		Week 24	94.7	100.0	-5.3
Placebo		Week 24	90.7	98.0	-7.3
Placebo		Week 26	102.7	94.7	8.0
Placebo		Week 26	98.0	100.0	-2.0
Placebo		Week 26	93.3	98.0	-4.7
Placebo		Week 4	105.3	94.7	10.7
Placebo		Week 4	106.7	100.0	6.7
Placebo		Week 4	106.7	98.0	8.7
Placebo		Week 6	96.7	94.7	2.0
Placebo		Week 6	91.3	100.0	-8.7
Placebo		Week 6	93.3	98.0	-4.7
Placebo		Week 8	104.7	94.7	10.0
Placebo		Week 8	95.3	100.0	-4.7
Placebo		Week 8	104.7	98.0	6.7
Placebo			104.7	94.7
Placebo			104.0	100.0
Placebo			100.7	98.0
Placebo			112.0	94.7
Placebo			104.0	100.0
Placebo			101.3	98.0
Xanomeline Low Dose		Week 2	83.3	99.3	-16.0
Xanomeline Low Dose		Week 2	84.0	96.7	-12.7
Xanomeline Low Dose		Week 2	80.0	96.0	-16.0
Xanomeline Low Dose		Week 4	101.3	99.3	2.0
Xanomeline Low Dose		Week 4	100.7	96.7	4.0
Xanomeline Low Dose		Week 4	99.3	96.0	3.3
Xanomeline Low Dose		Week 6	86.7	99.3	-12.7
Xanomeline Low Dose		Week 6	101.3	96.7	4.7
Xanomeline Low Dose		Week 6	99.3	96.0	3.3
Xanomeline Low Dose		Week 8	95.3	99.3	-4.0
Xanomeline Low Dose		Week 8	96.0	96.7	-0.7
Xanomeline Low Dose		Week 8	96.7	96.0	0.7
Xanomeline Low Dose			83.3	99.3
Xanomeline Low Dose			96.0	96.7
Xanomeline Low Dose			88.7	96.0
Xanomeline Low Dose			93.3	99.3
Xanomeline Low Dose			92.7	96.7
Xanomeline Low Dose			90.0	96.0
Xanomeline Low Dose		Week 12	92.0	87.3	4.7
Xanomeline Low Dose		Week 12	80.0	90.7	-10.7
Xanomeline Low Dose		Week 12	85.3	86.7	-1.3
Xanomeline Low Dose		Week 16	94.7	87.3	7.3
Xanomeline Low Dose		Week 16	101.3	90.7	10.7
Xanomeline Low Dose		Week 16	104.7	86.7	18.0
Xanomeline Low Dose		Week 2	88.7	87.3	1.3
Xanomeline Low Dose		Week 2	92.0	90.7	1.3
Xanomeline Low Dose		Week 2	93.3	86.7	6.7
Xanomeline Low Dose		Week 20	82.0	87.3	-5.3
Xanomeline Low Dose		Week 20	86.7	90.7	-4.0
Xanomeline Low Dose		Week 20	82.0	86.7	-4.7
Xanomeline Low Dose		Week 24	90.7	87.3	3.3
Xanomeline Low Dose		Week 24	77.3	90.7	-13.3
Xanomeline Low Dose		Week 24	80.0	86.7	-6.7
Xanomeline Low Dose		Week 26	90.7	87.3	3.3
Xanomeline Low Dose		Week 26	87.3	90.7	-3.3
Xanomeline Low Dose		Week 26	86.0	86.7	-0.7
Xanomeline Low Dose		Week 4	80.7	87.3	-6.7
Xanomeline Low Dose		Week 4	78.7	90.7	-12.0
Xanomeline Low Dose		Week 4	82.0	86.7	-4.7
Xanomeline Low Dose		Week 6	87.3	87.3	0.0
Xanomeline Low Dose		Week 6	86.7	90.7	-4.0
Xanomeline Low Dose		Week 6	84.7	86.7	-2.0
Xanomeline Low Dose		Week 8	79.3	87.3	-8.0
Xanomeline Low Dose		Week 8	76.7	90.7	-14.0
Xanomeline Low Dose		Week 8	78.7	86.7	-8.0
Xanomeline High Dose		Week 12	87.3	111.3	-24.0
Xanomeline High Dose		Week 12	88.7	104.7	-16.0
Xanomeline High Dose		Week 12	90.7	110.7	-20.0
Xanomeline High Dose		Week 16	89.3	111.3	-22.0
Xanomeline High Dose		Week 16	90.7	104.7	-14.0
Xanomeline High Dose		Week 16	89.3	110.7	-21.3
Xanomeline High Dose		Week 2	87.3	111.3	-24.0
Xanomeline High Dose		Week 2	93.3	104.7	-11.3
Xanomeline High Dose		Week 2	86.7	110.7	-24.0
Xanomeline High Dose		Week 20	92.0	111.3	-19.3
Xanomeline High Dose		Week 20	90.0	104.7	-14.7
Xanomeline High Dose		Week 20	96.7	110.7	-14.0
Xanomeline High Dose		Week 24	92.7	111.3	-18.7
Xanomeline High Dose		Week 24	91.3	104.7	-13.3
Xanomeline High Dose		Week 24	90.7	110.7	-20.0
Xanomeline High Dose		Week 26	80.0	111.3	-31.3
Xanomeline High Dose		Week 26	80.7	104.7	-24.0
Xanomeline High Dose		Week 26	91.3	110.7	-19.3
Xanomeline High Dose		Week 4	90.7	111.3	-20.7
Xanomeline High Dose		Week 4	92.0	104.7	-12.7
Xanomeline High Dose		Week 4	104.7	110.7	-6.0
Xanomeline High Dose		Week 6	95.3	111.3	-16.0
Xanomeline High Dose		Week 6	98.0	104.7	-6.7
Xanomeline High Dose		Week 6	99.3	110.7	-11.3
Xanomeline High Dose		Week 8	90.0	111.3	-21.3
Xanomeline High Dose		Week 8	94.0	104.7	-10.7
Xanomeline High Dose		Week 8	88.0	110.7	-22.7
Xanomeline High Dose			95.3	111.3
Xanomeline High Dose			100.7	104.7
Xanomeline High Dose			98.7	110.7
Placebo		Week 12	91.3	94.7	-3.3
Placebo		Week 12	86.7	87.3	-0.7
Placebo		Week 12	88.0	89.3	-1.3
Placebo		Week 16	94.0	94.7	-0.7
Placebo		Week 16	84.0	87.3	-3.3
Placebo		Week 16	84.0	89.3	-5.3
Placebo		Week 2	91.3	94.7	-3.3
Placebo		Week 2	85.3	87.3	-2.0
Placebo		Week 2	82.0	89.3	-7.3
Placebo		Week 20	98.7	94.7	4.0
Placebo		Week 20	92.0	87.3	4.7
Placebo		Week 20	94.0	89.3	4.7
Placebo		Week 24	77.3	94.7	-17.3
Placebo		Week 24	76.0	87.3	-11.3
Placebo		Week 24	84.7	89.3	-4.7
Placebo		Week 26	96.0	94.7	1.3
Placebo		Week 26	86.0	87.3	-1.3
Placebo		Week 26	77.3	89.3	-12.0
Placebo		Week 4	87.3	94.7	-7.3
Placebo		Week 4	79.3	87.3	-8.0
Placebo		Week 4	82.0	89.3	-7.3
Placebo		Week 6	92.7	94.7	-2.0
Placebo		Week 6	83.3	87.3	-4.0
Placebo		Week 6	82.0	89.3	-7.3
Placebo		Week 8	87.3	94.7	-7.3
Placebo		Week 8	82.7	87.3	-4.7
Placebo		Week 8	85.3	89.3	-4.0
Placebo			97.3	94.7
Placebo			88.7	87.3
Placebo			96.7	89.3
Placebo			90.0	94.7
Placebo			89.3	87.3
Placebo			86.0	89.3
Xanomeline Low Dose		Week 12	111.0	88.0	23.0
Xanomeline Low Dose		Week 12	93.0	84.3	8.7
Xanomeline Low Dose		Week 12	95.3	80.0	15.3
Xanomeline Low Dose		Week 16	88.7	88.0	0.7
Xanomeline Low Dose		Week 16	81.3	84.3	-3.0
Xanomeline Low Dose		Week 16	81.0	80.0	1.0
Xanomeline Low Dose		Week 2	90.3	88.0	2.3
Xanomeline Low Dose		Week 2	78.0	84.3	-6.3
Xanomeline Low Dose		Week 2	75.7	80.0	-4.3
Xanomeline Low Dose		Week 20	91.7	88.0	3.7
Xanomeline Low Dose		Week 20	84.0	84.3	-0.3
Xanomeline Low Dose		Week 20	102.7	80.0	22.7
Xanomeline Low Dose		Week 24	96.0	88.0	8.0
Xanomeline Low Dose		Week 24	86.0	84.3	1.7
Xanomeline Low Dose		Week 24	92.0	80.0	12.0
Xanomeline Low Dose		Week 26	91.3	88.0	3.3
Xanomeline Low Dose		Week 26	89.3	84.3	5.0
Xanomeline Low Dose		Week 26	79.7	80.0	-0.3
Xanomeline Low Dose		Week 4	102.0	88.0	14.0
Xanomeline Low Dose		Week 4	86.3	84.3	2.0
Xanomeline Low Dose		Week 4	96.7	80.0	16.7
Xanomeline Low Dose		Week 6	94.3	88.0	6.3
Xanomeline Low Dose		Week 6	73.3	84.3	-11.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	85.3	88.0	-2.7
Xanomeline Low Dose		Week 8	86.3	84.3	2.0
Xanomeline Low Dose		Week 8	81.0	80.0	1.0
Xanomeline Low Dose			82.7	88.0
Xanomeline Low Dose			85.7	84.3
Xanomeline Low Dose			88.7	80.0
Xanomeline Low Dose			96.0	88.0
Xanomeline Low Dose			82.3	84.3
Xanomeline Low Dose			96.7	80.0
Xanomeline Low Dose		Week 2	95.7	86.0	9.7
Xanomeline Low Dose		Week 2	96.7	99.3	-2.7
Xanomeline Low Dose		Week 2	112.7	95.3	17.3
Xanomeline Low Dose		Week 4	88.0	86.0	2.0
Xanomeline Low Dose		Week 4	96.0	99.3	-3.3
Xanomeline Low Dose		Week 4	97.0	95.3	1.7
Xanomeline Low Dose		Week 6	83.7	86.0	-2.3
Xanomeline Low Dose		Week 6	101.0	99.3	1.7
Xanomeline Low Dose		Week 6	88.7	95.3	-6.7
Xanomeline Low Dose		Week 8	91.7	86.0	5.7
Xanomeline Low Dose		Week 8	90.7	99.3	-8.7
Xanomeline Low Dose		Week 8	86.7	95.3	-8.7
Xanomeline Low Dose			89.0	86.0
Xanomeline Low Dose			102.7	99.3
Xanomeline Low Dose			99.7	95.3
Xanomeline Low Dose			94.0	86.0
Xanomeline Low Dose			104.7	99.3
Xanomeline Low Dose			84.0	95.3
Placebo		Week 2	97.7	88.3	9.3
Placebo		Week 2	104.7	101.3	3.3
Placebo		Week 2	105.3	100.0	5.3
Placebo		Week 4	101.7	88.3	13.3
Placebo		Week 4	107.3	101.3	6.0
Placebo		Week 4	98.7	100.0	-1.3
Placebo			94.0	88.3
Placebo			101.0	101.3
Placebo			103.3	100.0
Placebo			90.7	88.3
Placebo			106.0	101.3
Placebo			107.7	100.0
Placebo		Week 12	95.7	106.7	-11.0
Placebo		Week 12	102.3	100.7	1.7
Placebo		Week 12	98.3	105.3	-7.0
Placebo		Week 16	103.3	106.7	-3.3
Placebo		Week 16	100.7	100.7	0.0
Placebo		Week 16	94.3	105.3	-11.0
Placebo		Week 2	100.7	106.7	-6.0
Placebo		Week 2	97.3	100.7	-3.3
Placebo		Week 2	104.3	105.3	-1.0
Placebo		Week 20	74.3	106.7	-32.3
Placebo		Week 20	78.7	100.7	-22.0
Placebo		Week 20	80.3	105.3	-25.0
Placebo		Week 24	90.7	106.7	-16.0
Placebo		Week 24	90.3	100.7	-10.3
Placebo		Week 24	105.7	105.3	0.3
Placebo		Week 4	92.7	106.7	-14.0
Placebo		Week 4	102.0	100.7	1.3
Placebo		Week 4	98.3	105.3	-7.0
Placebo		Week 6	91.3	106.7	-15.3
Placebo		Week 6	98.0	100.7	-2.7
Placebo		Week 6	91.3	105.3	-14.0
Placebo		Week 8	103.3	106.7	-3.3
Placebo		Week 8	106.7	100.7	6.0
Placebo		Week 8	107.3	105.3	2.0
Placebo			98.7	106.7
Placebo			99.7	100.7
Placebo			101.0	105.3
Placebo			92.0	106.7
Placebo			111.3	100.7
Placebo			89.0	105.3
Xanomeline High Dose		Week 2	82.7	84.3	-1.7
Xanomeline High Dose		Week 2	90.7	80.0	10.7
Xanomeline High Dose		Week 2	89.7	87.3	2.3
Xanomeline High Dose			88.0	84.3
Xanomeline High Dose			95.0	80.0
Xanomeline High Dose			100.3	87.3
Xanomeline High Dose		Week 2	92.7	103.0	-10.3
Xanomeline High Dose		Week 2	96.3	110.3	-14.0
Xanomeline High Dose		Week 2	96.3	98.7	-2.3
Xanomeline High Dose		Week 4	103.3	103.0	0.3
Xanomeline High Dose		Week 4	114.7	110.3	4.3
Xanomeline High Dose		Week 4	113.0	98.7	14.3
Xanomeline High Dose		Week 6	96.7	103.0	-6.3
Xanomeline High Dose		Week 6	107.3	110.3	-3.0
Xanomeline High Dose		Week 6	100.0	98.7	1.3
Xanomeline High Dose		Week 8	91.0	103.0	-12.0
Xanomeline High Dose		Week 8	98.0	110.3	-12.3
Xanomeline High Dose		Week 8	94.0	98.7	-4.7
Xanomeline High Dose			105.0	103.0
Xanomeline High Dose			108.3	110.3
Xanomeline High Dose			104.7	98.7
Xanomeline High Dose			89.3	103.0
Xanomeline High Dose			93.0	110.3
Xanomeline High Dose			92.7	98.7
Placebo		Week 12	81.0	99.3	-18.3
Placebo		Week 12	92.7	107.0	-14.3
Placebo		Week 12	84.3	105.0	-20.7
Placebo		Week 16	90.3	99.3	-9.0
Placebo		Week 16	106.3	107.0	-0.7
Placebo		Week 16	96.0	105.0	-9.0
Placebo		Week 2	89.0	99.3	-10.3
Placebo		Week 2	97.3	107.0	-9.7
Placebo		Week 2	93.0	105.0	-12.0
Placebo		Week 20	93.0	99.3	-6.3
Placebo		Week 20	95.0	107.0	-12.0
Placebo		Week 20	83.3	105.0	-21.7
Placebo		Week 24	95.7	99.3	-3.7
Placebo		Week 24	86.7	107.0	-20.3
Placebo		Week 24	90.0	105.0	-15.0
Placebo		Week 4	91.3	99.3	-8.0
Placebo		Week 4	100.0	107.0	-7.0
Placebo		Week 4	98.0	105.0	-7.0
Placebo		Week 6	94.3	99.3	-5.0
Placebo		Week 6	92.3	107.0	-14.7
Placebo		Week 6	101.0	105.0	-4.0
Placebo		Week 8	110.7	99.3	11.3
Placebo		Week 8	94.7	107.0	-12.3
Placebo		Week 8	97.3	105.0	-7.7
Placebo			100.3	99.3
Placebo			98.3	107.0
Placebo			96.0	105.0
Placebo			95.7	99.3
Placebo			100.3	107.0
Placebo			91.0	105.0
Placebo		Week 12	104.7	110.0	-5.3
Placebo		Week 12	103.3	109.3	-6.0
Placebo		Week 12	104.7	112.7	-8.0
Placebo		Week 16	118.0	110.0	8.0
Placebo		Week 16	109.3	109.3	0.0
Placebo		Week 16	113.3	112.7	0.7
Placebo		Week 2	111.3	110.0	1.3
Placebo		Week 2	106.7	109.3	-2.7
Placebo		Week 2	117.3	112.7	4.7
Placebo		Week 20	110.0	110.0	0.0
Placebo		Week 20	115.3	109.3	6.0
Placebo		Week 20	115.3	112.7	2.7
Placebo		Week 24	89.3	110.0	-20.7
Placebo		Week 24	92.0	109.3	-17.3
Placebo		Week 24	91.3	112.7	-21.3
Placebo		Week 26	95.3	110.0	-14.7
Placebo		Week 26	93.3	109.3	-16.0
Placebo		Week 26	94.7	112.7	-18.0
Placebo		Week 4	96.7	110.0	-13.3
Placebo		Week 4	93.3	109.3	-16.0
Placebo		Week 4	94.7	112.7	-18.0
Placebo		Week 6	96.7	110.0	-13.3
Placebo		Week 6	111.3	109.3	2.0
Placebo		Week 6	88.0	112.7	-24.7
Placebo		Week 8	106.7	110.0	-3.3
Placebo		Week 8	116.7	109.3	7.3
Placebo		Week 8	102.7	112.7	-10.0
Placebo			110.7	110.0
Placebo			106.7	109.3
Placebo			106.7	112.7
Placebo			99.3	110.0
Placebo			98.0	109.3
Placebo			100.0	112.7
Placebo		Week 12	106.7	124.0	-17.3
Placebo		Week 12	93.3	129.3	-36.0
Placebo		Week 12	116.7	134.7	-18.0
Placebo		Week 16	100.0	124.0	-24.0
Placebo		Week 16	102.0	129.3	-27.3
Placebo		Week 16	100.0	134.7	-34.7
Placebo		Week 2	103.3	124.0	-20.7
Placebo		Week 2	106.0	129.3	-23.3
Placebo		Week 2	105.3	134.7	-29.3
Placebo		Week 20	123.3	124.0	-0.7
Placebo		Week 20	123.3	129.3	-6.0
Placebo		Week 20	122.0	134.7	-12.7
Placebo		Week 24	125.3	124.0	1.3
Placebo		Week 24	136.7	129.3	7.3
Placebo		Week 24	136.7	134.7	2.0
Placebo		Week 26	113.3	124.0	-10.7
Placebo		Week 26	115.3	129.3	-14.0
Placebo		Week 26	114.0	134.7	-20.7
Placebo		Week 4	112.0	124.0	-12.0
Placebo		Week 4	109.3	129.3	-20.0
Placebo		Week 4	108.0	134.7	-26.7
Placebo		Week 6	133.3	124.0	9.3
Placebo		Week 6	140.0	129.3	10.7
Placebo		Week 6	136.7	134.7	2.0
Placebo		Week 8	116.0	124.0	-8.0
Placebo		Week 8	121.3	129.3	-8.0
Placebo		Week 8	113.3	134.7	-21.3
Placebo			107.3	124.0
Placebo			120.0	129.3
Placebo			131.3	134.7
Placebo			100.0	124.0
Placebo			102.0	129.3
Placebo			101.3	134.7
Placebo		Week 12	104.0	101.3	2.7
Placebo		Week 12	88.7	99.3	-10.7
Placebo		Week 12	92.0	96.7	-4.7
Placebo		Week 16	99.3	101.3	-2.0
Placebo		Week 16	102.0	99.3	2.7
Placebo		Week 16	99.3	96.7	2.7
Placebo		Week 2	114.7	101.3	13.3
Placebo		Week 2	90.0	99.3	-9.3
Placebo		Week 2	89.3	96.7	-7.3
Placebo		Week 20	108.0	101.3	6.7
Placebo		Week 20	109.3	99.3	10.0
Placebo		Week 20	106.7	96.7	10.0
Placebo		Week 24	107.3	101.3	6.0
Placebo		Week 24	105.3	99.3	6.0
Placebo		Week 24	98.7	96.7	2.0
Placebo		Week 26	105.3	101.3	4.0
Placebo		Week 26	105.3	99.3	6.0
Placebo		Week 26	104.0	96.7	7.3
Placebo		Week 4	104.7	101.3	3.3
Placebo		Week 4	86.7	99.3	-12.7
Placebo		Week 4	91.3	96.7	-5.3
Placebo		Week 6	114.7	101.3	13.3
Placebo		Week 6	100.0	99.3	0.7
Placebo		Week 6	98.0	96.7	1.3
Placebo		Week 8	109.3	101.3	8.0
Placebo		Week 8	108.0	99.3	8.7
Placebo		Week 8	110.0	96.7	13.3
Placebo			100.7	101.3
Placebo			84.7	99.3
Placebo			86.7	96.7
Placebo			100.7	101.3
Placebo			92.7	99.3
Placebo			91.3	96.7
Xanomeline Low Dose		Week 12	99.3	123.3	-24.0
Xanomeline Low Dose		Week 12	102.0	110.0	-8.0
Xanomeline Low Dose		Week 12	108.0	120.0	-12.0
Xanomeline Low Dose		Week 2	108.7	123.3	-14.7
Xanomeline Low Dose		Week 2	113.3	110.0	3.3
Xanomeline Low Dose		Week 2	127.3	120.0	7.3
Xanomeline Low Dose		Week 4	100.0	123.3	-23.3
Xanomeline Low Dose		Week 4	103.3	110.0	-6.7
Xanomeline Low Dose		Week 4	107.3	120.0	-12.7
Xanomeline Low Dose		Week 6	100.0	123.3	-23.3
Xanomeline Low Dose		Week 6	100.7	110.0	-9.3
Xanomeline Low Dose		Week 6	103.3	120.0	-16.7
Xanomeline Low Dose		Week 8	107.3	123.3	-16.0
Xanomeline Low Dose		Week 8	110.0	110.0	0.0
Xanomeline Low Dose		Week 8	126.7	120.0	6.7
Xanomeline Low Dose			120.0	123.3
Xanomeline Low Dose			110.0	110.0
Xanomeline Low Dose			122.7	120.0
Xanomeline Low Dose			108.7	123.3
Xanomeline Low Dose			124.0	110.0
Xanomeline Low Dose			112.7	120.0
Xanomeline High Dose		Week 2	99.3	107.3	-8.0
Xanomeline High Dose		Week 2	73.3	108.7	-35.3
Xanomeline High Dose		Week 2	85.3	111.3	-26.0
Xanomeline High Dose		Week 4	93.3	107.3	-14.0
Xanomeline High Dose		Week 4	78.0	108.7	-30.7
Xanomeline High Dose		Week 4	92.0	111.3	-19.3
Xanomeline High Dose		Week 6	112.0	107.3	4.7
Xanomeline High Dose		Week 6	101.3	108.7	-7.3
Xanomeline High Dose		Week 6	96.0	111.3	-15.3
Xanomeline High Dose		Week 8	113.3	107.3	6.0
Xanomeline High Dose		Week 8	111.3	108.7	2.7
Xanomeline High Dose		Week 8	113.3	111.3	2.0
Xanomeline High Dose			102.0	107.3
Xanomeline High Dose			90.0	108.7
Xanomeline High Dose			92.0	111.3
Xanomeline High Dose			107.3	107.3
Xanomeline High Dose			91.3	108.7
Xanomeline High Dose			104.0	111.3
Xanomeline Low Dose		Week 2	80.7	105.3	-24.7
Xanomeline Low Dose		Week 2	86.7	92.7	-6.0
Xanomeline Low Dose		Week 2	89.3	107.3	-18.0
Xanomeline Low Dose		Week 4	83.3	105.3	-22.0
Xanomeline Low Dose		Week 4	82.7	92.7	-10.0
Xanomeline Low Dose		Week 4	84.0	107.3	-23.3
Xanomeline Low Dose			97.3	105.3
Xanomeline Low Dose			96.7	92.7
Xanomeline Low Dose			94.7	107.3
Xanomeline Low Dose			98.0	105.3
Xanomeline Low Dose			75.3	92.7
Xanomeline Low Dose			92.7	107.3
Xanomeline Low Dose		Week 12	93.3	94.0	-0.7
Xanomeline Low Dose		Week 12	103.3	95.3	8.0
Xanomeline Low Dose		Week 12	106.7	94.0	12.7
Xanomeline Low Dose		Week 16	91.3	94.0	-2.7
Xanomeline Low Dose		Week 16	86.7	95.3	-8.7
Xanomeline Low Dose		Week 16	94.7	94.0	0.7
Xanomeline Low Dose		Week 2	86.0	94.0	-8.0
Xanomeline Low Dose		Week 2	90.0	95.3	-5.3
Xanomeline Low Dose		Week 2	85.3	94.0	-8.7
Xanomeline Low Dose		Week 20	76.7	94.0	-17.3
Xanomeline Low Dose		Week 20	79.3	95.3	-16.0
Xanomeline Low Dose		Week 20	84.0	94.0	-10.0
Xanomeline Low Dose		Week 24	94.0	94.0	0.0
Xanomeline Low Dose		Week 24	93.3	95.3	-2.0
Xanomeline Low Dose		Week 24	90.7	94.0	-3.3
Xanomeline Low Dose		Week 26	84.0	94.0	-10.0
Xanomeline Low Dose		Week 26	81.3	95.3	-14.0
Xanomeline Low Dose		Week 26	76.7	94.0	-17.3
Xanomeline Low Dose		Week 4	96.7	94.0	2.7
Xanomeline Low Dose		Week 4	100.7	95.3	5.3
Xanomeline Low Dose		Week 4	100.0	94.0	6.0
Xanomeline Low Dose		Week 6	92.7	94.0	-1.3
Xanomeline Low Dose		Week 6	96.0	95.3	0.7
Xanomeline Low Dose		Week 6	99.3	94.0	5.3
Xanomeline Low Dose		Week 8	90.0	94.0	-4.0
Xanomeline Low Dose		Week 8	92.0	95.3	-3.3
Xanomeline Low Dose		Week 8	90.7	94.0	-3.3
Xanomeline Low Dose			85.3	94.0
Xanomeline Low Dose			91.3	95.3
Xanomeline Low Dose			90.0	94.0
Xanomeline Low Dose			88.0	94.0
Xanomeline Low Dose			100.7	95.3
Xanomeline Low Dose			98.0	94.0
Placebo		Week 12	104.0	101.3	2.7
Placebo		Week 12	108.7	109.3	-0.7
Placebo		Week 12	112.7	98.0	14.7
Placebo		Week 16	113.3	101.3	12.0
Placebo		Week 16	111.3	109.3	2.0
Placebo		Week 16	108.0	98.0	10.0
Placebo		Week 2	104.7	101.3	3.3
Placebo		Week 2	111.3	109.3	2.0
Placebo		Week 2	120.0	98.0	22.0
Placebo		Week 20	114.7	101.3	13.3
Placebo		Week 20	125.3	109.3	16.0
Placebo		Week 20	126.7	98.0	28.7
Placebo		Week 24	95.3	101.3	-6.0
Placebo		Week 24	88.7	109.3	-20.7
Placebo		Week 24	91.3	98.0	-6.7
Placebo		Week 26	96.7	101.3	-4.7
Placebo		Week 26	90.7	109.3	-18.7
Placebo		Week 26	93.3	98.0	-4.7
Placebo		Week 4	96.7	101.3	-4.7
Placebo		Week 4	101.3	109.3	-8.0
Placebo		Week 4	103.3	98.0	5.3
Placebo		Week 6	94.7	101.3	-6.7
Placebo		Week 6	102.0	109.3	-7.3
Placebo		Week 6	99.3	98.0	1.3
Placebo		Week 8	99.3	101.3	-2.0
Placebo		Week 8	96.0	109.3	-13.3
Placebo		Week 8	94.0	98.0	-4.0
Placebo			113.3	101.3
Placebo			106.0	109.3
Placebo			116.0	98.0
Placebo			104.7	101.3
Placebo			112.0	109.3
Placebo			116.7	98.0
Xanomeline Low Dose		Week 12	94.7	94.7	0.0
Xanomeline Low Dose		Week 12	97.3	86.0	11.3
Xanomeline Low Dose		Week 12	95.3	66.7	28.7
Xanomeline Low Dose		Week 2	100.0	94.7	5.3
Xanomeline Low Dose		Week 2	91.3	86.0	5.3
Xanomeline Low Dose		Week 2	91.3	66.7	24.7
Xanomeline Low Dose		Week 4	88.0	94.7	-6.7
Xanomeline Low Dose		Week 4	90.0	86.0	4.0
Xanomeline Low Dose		Week 4	88.0	66.7	21.3
Xanomeline Low Dose		Week 6	93.3	94.7	-1.3
Xanomeline Low Dose		Week 6	98.7	86.0	12.7
Xanomeline Low Dose		Week 6	96.0	66.7	29.3
Xanomeline Low Dose		Week 8	98.7	94.7	4.0
Xanomeline Low Dose		Week 8	99.3	86.0	13.3
Xanomeline Low Dose		Week 8	99.3	66.7	32.7
Xanomeline Low Dose			88.0	94.7
Xanomeline Low Dose			90.0	86.0
Xanomeline Low Dose			90.7	66.7
Xanomeline Low Dose			85.3	94.7
Xanomeline Low Dose			83.3	86.0
Xanomeline Low Dose			85.3	66.7
Xanomeline Low Dose		Week 12	78.0	91.3	-13.3
Xanomeline Low Dose		Week 12	80.0	90.0	-10.0
Xanomeline Low Dose		Week 12	79.3	90.7	-11.3
Xanomeline Low Dose		Week 16	100.7	91.3	9.3
Xanomeline Low Dose		Week 16	94.7	90.0	4.7
Xanomeline Low Dose		Week 16	96.0	90.7	5.3
Xanomeline Low Dose		Week 2	94.7	91.3	3.3
Xanomeline Low Dose		Week 2	93.3	90.0	3.3
Xanomeline Low Dose		Week 2	95.3	90.7	4.7
Xanomeline Low Dose		Week 20	86.7	91.3	-4.7
Xanomeline Low Dose		Week 20	89.3	90.0	-0.7
Xanomeline Low Dose		Week 20	85.3	90.7	-5.3
Xanomeline Low Dose		Week 24	84.0	91.3	-7.3
Xanomeline Low Dose		Week 24	87.3	90.0	-2.7
Xanomeline Low Dose		Week 24	82.0	90.7	-8.7
Xanomeline Low Dose		Week 4	85.3	91.3	-6.0
Xanomeline Low Dose		Week 4	83.3	90.0	-6.7
Xanomeline Low Dose		Week 4	81.3	90.7	-9.3
Xanomeline Low Dose		Week 6	90.7	91.3	-0.7
Xanomeline Low Dose		Week 6	91.3	90.0	1.3
Xanomeline Low Dose		Week 6	94.0	90.7	3.3
Xanomeline Low Dose		Week 8	94.0	91.3	2.7
Xanomeline Low Dose		Week 8	93.3	90.0	3.3
Xanomeline Low Dose		Week 8	92.0	90.7	1.3
Xanomeline Low Dose			90.0	91.3
Xanomeline Low Dose			89.3	90.0
Xanomeline Low Dose			90.0	90.7
Xanomeline Low Dose			70.0	91.3
Xanomeline Low Dose			86.0	90.0
Xanomeline Low Dose			82.7	90.7
Placebo		Week 12	86.0	94.7	-8.7
Placebo		Week 12	90.7	97.3	-6.7
Placebo		Week 12	90.0	98.7	-8.7
Placebo		Week 16	84.0	94.7	-10.7
Placebo		Week 16	78.0	97.3	-19.3
Placebo		Week 16	78.0	98.7	-20.7
Placebo		Week 2	83.3	94.7	-11.3
Placebo		Week 2	86.0	97.3	-11.3
Placebo		Week 2	87.3	98.7	-11.3
Placebo		Week 20	90.7	94.7	-4.0
Placebo		Week 20	85.3	97.3	-12.0
Placebo		Week 20	90.0	98.7	-8.7
Placebo		Week 24	95.3	94.7	0.7
Placebo		Week 24	86.7	97.3	-10.7
Placebo		Week 24	90.0	98.7	-8.7
Placebo		Week 26	90.7	94.7	-4.0
Placebo		Week 26	89.3	97.3	-8.0
Placebo		Week 26	91.3	98.7	-7.3
Placebo		Week 4	90.7	94.7	-4.0
Placebo		Week 4	92.7	97.3	-4.7
Placebo		Week 4	91.3	98.7	-7.3
Placebo		Week 6	86.7	94.7	-8.0
Placebo		Week 6	83.3	97.3	-14.0
Placebo		Week 6	86.7	98.7	-12.0
Placebo		Week 8	83.3	94.7	-11.3
Placebo		Week 8	82.0	97.3	-15.3
Placebo		Week 8	92.7	98.7	-6.0
Placebo			92.7	94.7
Placebo			101.3	97.3
Placebo			101.3	98.7
Placebo			77.3	94.7
Placebo			82.0	97.3
Placebo			81.3	98.7
Xanomeline Low Dose		Week 12	86.7	91.3	-4.7
Xanomeline Low Dose		Week 12	76.0	89.3	-13.3
Xanomeline Low Dose		Week 12	92.7	88.0	4.7
Xanomeline Low Dose		Week 16	78.0	91.3	-13.3
Xanomeline Low Dose		Week 16	81.3	89.3	-8.0
Xanomeline Low Dose		Week 16	82.0	88.0	-6.0
Xanomeline Low Dose		Week 2	89.3	91.3	-2.0
Xanomeline Low Dose		Week 2	90.7	89.3	1.3
Xanomeline Low Dose		Week 2	94.7	88.0	6.7
Xanomeline Low Dose		Week 20	96.7	91.3	5.3
Xanomeline Low Dose		Week 20	90.0	89.3	0.7
Xanomeline Low Dose		Week 20	96.0	88.0	8.0
Xanomeline Low Dose		Week 24	94.0	91.3	2.7
Xanomeline Low Dose		Week 24	96.7	89.3	7.3
Xanomeline Low Dose		Week 24	92.0	88.0	4.0
Xanomeline Low Dose		Week 4	93.3	91.3	2.0
Xanomeline Low Dose		Week 4	94.0	89.3	4.7
Xanomeline Low Dose		Week 4	94.0	88.0	6.0
Xanomeline Low Dose		Week 6	87.3	91.3	-4.0
Xanomeline Low Dose		Week 6	86.7	89.3	-2.7
Xanomeline Low Dose		Week 6	86.7	88.0	-1.3
Xanomeline Low Dose		Week 8	86.0	91.3	-5.3
Xanomeline Low Dose		Week 8	88.7	89.3	-0.7
Xanomeline Low Dose		Week 8	86.0	88.0	-2.0
Xanomeline Low Dose			90.7	91.3
Xanomeline Low Dose			95.3	89.3
Xanomeline Low Dose			102.0	88.0
Xanomeline Low Dose			86.0	91.3
Xanomeline Low Dose			86.0	89.3
Xanomeline Low Dose			86.7	88.0
Placebo		Week 12	84.7	78.0	6.7
Placebo		Week 12	86.7	86.0	0.7
Placebo		Week 12	96.7	90.0	6.7
Placebo		Week 16	86.7	78.0	8.7
Placebo		Week 16	84.7	86.0	-1.3
Placebo		Week 16	94.0	90.0	4.0
Placebo		Week 2	90.0	78.0	12.0
Placebo		Week 2	92.0	86.0	6.0
Placebo		Week 2	100.0	90.0	10.0
Placebo		Week 20	79.3	78.0	1.3
Placebo		Week 20	83.3	86.0	-2.7
Placebo		Week 20	94.7	90.0	4.7
Placebo		Week 24	87.3	78.0	9.3
Placebo		Week 24	96.7	86.0	10.7
Placebo		Week 24	96.7	90.0	6.7
Placebo		Week 26	90.7	78.0	12.7
Placebo		Week 26	90.7	86.0	4.7
Placebo		Week 26	97.3	90.0	7.3
Placebo		Week 4	80.0	78.0	2.0
Placebo		Week 4	89.3	86.0	3.3
Placebo		Week 4	90.7	90.0	0.7
Placebo		Week 6	76.7	78.0	-1.3
Placebo		Week 6	90.0	86.0	4.0
Placebo		Week 6	96.7	90.0	6.7
Placebo		Week 8	90.7	78.0	12.7
Placebo		Week 8	91.3	86.0	5.3
Placebo		Week 8	90.0	90.0	0.0
Xanomeline High Dose		Week 12	86.0	94.0	-8.0
Xanomeline High Dose		Week 12	88.0	89.3	-1.3
Xanomeline High Dose		Week 12	86.7	87.3	-0.7
Xanomeline High Dose		Week 16	88.7	94.0	-5.3
Xanomeline High Dose		Week 16	86.7	89.3	-2.7
Xanomeline High Dose		Week 16	80.0	87.3	-7.3
Xanomeline High Dose		Week 2	80.0	94.0	-14.0
Xanomeline High Dose		Week 2	87.3	89.3	-2.0
Xanomeline High Dose		Week 2	86.0	87.3	-1.3
Xanomeline High Dose		Week 4	82.7	94.0	-11.3
Xanomeline High Dose		Week 4	86.7	89.3	-2.7
Xanomeline High Dose		Week 4	86.7	87.3	-0.7
Xanomeline High Dose		Week 6	86.7	94.0	-7.3
Xanomeline High Dose		Week 6	85.3	89.3	-4.0
Xanomeline High Dose		Week 6	89.3	87.3	2.0
Xanomeline High Dose		Week 8	88.0	94.0	-6.0
Xanomeline High Dose		Week 8	90.0	89.3	0.7
Xanomeline High Dose		Week 8	90.7	87.3	3.3
Xanomeline High Dose			86.0	94.0
Xanomeline High Dose			81.3	89.3
Xanomeline High Dose			86.7	87.3
Xanomeline High Dose			86.0	94.0
Xanomeline High Dose			80.0	89.3
Xanomeline High Dose			81.3	87.3
Xanomeline High Dose		Week 2	102.0	98.0	4.0
Xanomeline High Dose		Week 2	100.0	93.3	6.7
Xanomeline High Dose		Week 2	103.3	96.0	7.3
Xanomeline High Dose		Week 4	106.0	98.0	8.0
Xanomeline High Dose		Week 4	107.3	93.3	14.0
Xanomeline High Dose		Week 4	105.3	96.0	9.3
Xanomeline High Dose			100.7	98.0
Xanomeline High Dose			95.3	93.3
Xanomeline High Dose			91.3	96.0
Xanomeline High Dose			92.0	98.0
Xanomeline High Dose			98.0	93.3
Xanomeline High Dose			96.0	96.0
Xanomeline Low Dose		Week 2	101.3	106.7	-5.3
Xanomeline Low Dose		Week 2	102.0	106.7	-4.7
Xanomeline Low Dose		Week 2	101.3	108.7	-7.3
Xanomeline Low Dose		Week 4	95.3	106.7	-11.3
Xanomeline Low Dose		Week 4	100.0	106.7	-6.7
Xanomeline Low Dose		Week 4	100.0	108.7	-8.7
Xanomeline Low Dose		Week 6	83.3	106.7	-23.3
Xanomeline Low Dose		Week 6	96.0	106.7	-10.7
Xanomeline Low Dose		Week 6	96.7	108.7	-12.0
Xanomeline Low Dose		Week 8	97.3	106.7	-9.3
Xanomeline Low Dose		Week 8	110.0	106.7	3.3
Xanomeline Low Dose		Week 8	108.7	108.7	0.0
Placebo		Week 2	95.3	112.0	-16.7
Placebo		Week 2	98.7	113.3	-14.7
Placebo		Week 2	94.7	110.7	-16.0
Placebo		Week 4	93.3	112.0	-18.7
Placebo		Week 4	90.7	113.3	-22.7
Placebo		Week 4	91.3	110.7	-19.3
Placebo		Week 6	94.0	112.0	-18.0
Placebo		Week 6	96.7	113.3	-16.7
Placebo		Week 6	91.3	110.7	-19.3
Placebo			92.7	112.0
Placebo			94.0	113.3
Placebo			93.3	110.7
Placebo			90.0	112.0
Placebo			88.0	113.3
Placebo			90.7	110.7
Xanomeline Low Dose		Week 12	74.7	88.0	-13.3
Xanomeline Low Dose		Week 12	76.7	92.0	-15.3
Xanomeline Low Dose		Week 12	87.3	89.3	-2.0
Xanomeline Low Dose		Week 16	83.3	88.0	-4.7
Xanomeline Low Dose		Week 16	103.3	92.0	11.3
Xanomeline Low Dose		Week 16	86.7	89.3	-2.7
Xanomeline Low Dose		Week 2	91.3	88.0	3.3
Xanomeline Low Dose		Week 2	99.3	92.0	7.3
Xanomeline Low Dose		Week 2	99.3	89.3	10.0
Xanomeline Low Dose		Week 4	85.3	88.0	-2.7
Xanomeline Low Dose		Week 4	96.7	92.0	4.7
Xanomeline Low Dose		Week 4	97.3	89.3	8.0
Xanomeline Low Dose		Week 6	86.7	88.0	-1.3
Xanomeline Low Dose		Week 6	87.3	92.0	-4.7
Xanomeline Low Dose		Week 6	84.7	89.3	-4.7
Xanomeline Low Dose		Week 8	99.3	88.0	11.3
Xanomeline Low Dose		Week 8	100.0	92.0	8.0
Xanomeline Low Dose		Week 8	100.7	89.3	11.3
Xanomeline High Dose		Week 12	86.0	116.0	-30.0
Xanomeline High Dose		Week 12	88.0	136.0	-48.0
Xanomeline High Dose		Week 12	92.0	128.0	-36.0
Xanomeline High Dose		Week 16	86.0	116.0	-30.0
Xanomeline High Dose		Week 16	93.3	136.0	-42.7
Xanomeline High Dose		Week 16	94.0	128.0	-34.0
Xanomeline High Dose		Week 2	100.0	116.0	-16.0
Xanomeline High Dose		Week 2	102.0	136.0	-34.0
Xanomeline High Dose		Week 2	101.3	128.0	-26.7
Xanomeline High Dose		Week 20	80.0	116.0	-36.0
Xanomeline High Dose		Week 20	84.7	136.0	-51.3
Xanomeline High Dose		Week 20	93.3	128.0	-34.7
Xanomeline High Dose		Week 24	113.3	116.0	-2.7
Xanomeline High Dose		Week 24	113.3	136.0	-22.7
Xanomeline High Dose		Week 24	108.7	128.0	-19.3
Xanomeline High Dose		Week 26	93.3	116.0	-22.7
Xanomeline High Dose		Week 26	102.0	136.0	-34.0
Xanomeline High Dose		Week 26	102.7	128.0	-25.3
Xanomeline High Dose		Week 4	102.7	116.0	-13.3
Xanomeline High Dose		Week 4	99.3	136.0	-36.7
Xanomeline High Dose		Week 4	104.0	128.0	-24.0
Xanomeline High Dose		Week 6	84.7	116.0	-31.3
Xanomeline High Dose		Week 6	96.0	136.0	-40.0
Xanomeline High Dose		Week 6	105.3	128.0	-22.7
Xanomeline High Dose		Week 8	91.0	116.0	-25.0
Xanomeline High Dose		Week 8	112.0	136.0	-24.0
Xanomeline High Dose		Week 8	116.7	128.0	-11.3
Xanomeline High Dose		Week 2	88.0	87.3	0.7
Xanomeline High Dose		Week 2	90.0	88.0	2.0
Xanomeline High Dose		Week 2	93.3	85.3	8.0
Xanomeline High Dose		Week 4	78.7	87.3	-8.7
Xanomeline High Dose		Week 4	76.0	88.0	-12.0
Xanomeline High Dose		Week 4	84.7	85.3	-0.7
Xanomeline High Dose		Week 6	81.3	87.3	-6.0
Xanomeline High Dose		Week 6	81.3	88.0	-6.7
Xanomeline High Dose		Week 6	80.0	85.3	-5.3
Xanomeline High Dose		Week 8	90.0	87.3	2.7
Xanomeline High Dose		Week 8	91.3	88.0	3.3
Xanomeline High Dose		Week 8	96.7	85.3	11.3
Xanomeline High Dose			81.3	87.3
Xanomeline High Dose			82.0	88.0
Xanomeline High Dose			82.7	85.3
Xanomeline High Dose			87.3	87.3
Xanomeline High Dose			83.3	88.0
Xanomeline High Dose			82.7	85.3
Xanomeline High Dose		Week 12	100.7	98.0	2.7
Xanomeline High Dose		Week 12	95.3	88.0	7.3
Xanomeline High Dose		Week 12	99.3	94.0	5.3
Xanomeline High Dose		Week 16	94.7	98.0	-3.3
Xanomeline High Dose		Week 16	91.3	88.0	3.3
Xanomeline High Dose		Week 16	95.3	94.0	1.3
Xanomeline High Dose		Week 2	103.3	98.0	5.3
Xanomeline High Dose		Week 2	110.0	88.0	22.0
Xanomeline High Dose		Week 2	108.0	94.0	14.0
Xanomeline High Dose		Week 20	80.7	98.0	-17.3
Xanomeline High Dose		Week 20	79.3	88.0	-8.7
Xanomeline High Dose		Week 20	79.3	94.0	-14.7
Xanomeline High Dose		Week 24	102.7	98.0	4.7
Xanomeline High Dose		Week 24	100.7	88.0	12.7
Xanomeline High Dose		Week 24	98.7	94.0	4.7
Xanomeline High Dose		Week 26	104.7	98.0	6.7
Xanomeline High Dose		Week 26	102.0	88.0	14.0
Xanomeline High Dose		Week 26	96.7	94.0	2.7
Xanomeline High Dose		Week 4	102.0	98.0	4.0
Xanomeline High Dose		Week 4	92.7	88.0	4.7
Xanomeline High Dose		Week 4	98.0	94.0	4.0
Xanomeline High Dose		Week 6	93.3	98.0	-4.7
Xanomeline High Dose		Week 6	90.7	88.0	2.7
Xanomeline High Dose		Week 6	93.3	94.0	-0.7
Xanomeline High Dose		Week 8	107.3	98.0	9.3
Xanomeline High Dose		Week 8	95.3	88.0	7.3
Xanomeline High Dose		Week 8	98.0	94.0	4.0
Xanomeline High Dose			100.0	98.0
Xanomeline High Dose			100.7	88.0
Xanomeline High Dose			100.0	94.0
Placebo		Week 12	80.7	88.7	-8.0
Placebo		Week 12	77.3	86.7	-9.3
Placebo		Week 12	78.0	88.0	-10.0
Placebo		Week 16	76.7	88.7	-12.0
Placebo		Week 16	77.3	86.7	-9.3
Placebo		Week 16	84.0	88.0	-4.0
Placebo		Week 2	89.3	88.7	0.7
Placebo		Week 2	76.7	86.7	-10.0
Placebo		Week 2	86.0	88.0	-2.0
Placebo		Week 20	88.0	88.7	-0.7
Placebo		Week 20	78.0	86.7	-8.7
Placebo		Week 20	78.0	88.0	-10.0
Placebo		Week 24	84.7	88.7	-4.0
Placebo		Week 24	82.7	86.7	-4.0
Placebo		Week 24	83.3	88.0	-4.7
Placebo		Week 26	78.0	88.7	-10.7
Placebo		Week 26	74.7	86.7	-12.0
Placebo		Week 26	78.7	88.0	-9.3
Placebo		Week 4	91.3	88.7	2.7
Placebo		Week 4	88.7	86.7	2.0
Placebo		Week 4	92.7	88.0	4.7
Placebo		Week 6	95.0	88.7	6.3
Placebo		Week 6	96.0	86.7	9.3
Placebo		Week 6	94.0	88.0	6.0
Placebo		Week 8	95.3	88.7	6.7
Placebo		Week 8	97.3	86.7	10.7
Placebo		Week 8	96.7	88.0	8.7
Placebo			95.3	88.7
Placebo			81.3	86.7
Placebo			90.0	88.0
Placebo			97.3	88.7
Placebo			94.7	86.7
Placebo			90.0	88.0
Xanomeline High Dose		Week 12	98.7	94.7	4.0
Xanomeline High Dose		Week 12	82.7	90.0	-7.3
Xanomeline High Dose		Week 12	88.7	92.7	-4.0
Xanomeline High Dose		Week 16	100.0	94.7	5.3
Xanomeline High Dose		Week 16	89.3	90.0	-0.7
Xanomeline High Dose		Week 16	98.0	92.7	5.3
Xanomeline High Dose		Week 2	80.7	94.7	-14.0
Xanomeline High Dose		Week 2	80.0	90.0	-10.0
Xanomeline High Dose		Week 2	73.3	92.7	-19.3
Xanomeline High Dose		Week 20	84.0	94.7	-10.7
Xanomeline High Dose		Week 20	79.3	90.0	-10.7
Xanomeline High Dose		Week 20	81.3	92.7	-11.3
Xanomeline High Dose		Week 24	79.3	94.7	-15.3
Xanomeline High Dose		Week 24	77.3	90.0	-12.7
Xanomeline High Dose		Week 24	83.3	92.7	-9.3
Xanomeline High Dose		Week 26	87.3	94.7	-7.3
Xanomeline High Dose		Week 26	85.3	90.0	-4.7
Xanomeline High Dose		Week 26	86.7	92.7	-6.0
Xanomeline High Dose		Week 4	114.0	94.7	19.3
Xanomeline High Dose		Week 4	111.3	90.0	21.3
Xanomeline High Dose		Week 4	108.7	92.7	16.0
Xanomeline High Dose		Week 6	74.0	94.7	-20.7
Xanomeline High Dose		Week 6	75.3	90.0	-14.7
Xanomeline High Dose		Week 6	78.0	92.7	-14.7
Xanomeline High Dose		Week 8	93.3	94.7	-1.3
Xanomeline High Dose		Week 8	95.3	90.0	5.3
Xanomeline High Dose		Week 8	94.0	92.7	1.3
Xanomeline High Dose			87.3	94.7
Xanomeline High Dose			86.7	90.0
Xanomeline High Dose			86.7	92.7
Xanomeline High Dose			89.3	94.7
Xanomeline High Dose			88.0	90.0
Xanomeline High Dose			89.3	92.7
Xanomeline Low Dose		Week 12	94.0	86.7	7.3
Xanomeline Low Dose		Week 12	91.3	88.7	2.7
Xanomeline Low Dose		Week 12	88.7	89.3	-0.7
Xanomeline Low Dose		Week 16	99.3	86.7	12.7
Xanomeline Low Dose		Week 16	91.3	88.7	2.7
Xanomeline Low Dose		Week 16	90.7	89.3	1.3
Xanomeline Low Dose		Week 2	94.0	86.7	7.3
Xanomeline Low Dose		Week 2	94.7	88.7	6.0
Xanomeline Low Dose		Week 2	94.0	89.3	4.7
Xanomeline Low Dose		Week 20	84.7	86.7	-2.0
Xanomeline Low Dose		Week 20	91.3	88.7	2.7
Xanomeline Low Dose		Week 20	93.3	89.3	4.0
Xanomeline Low Dose		Week 24	96.0	86.7	9.3
Xanomeline Low Dose		Week 24	90.0	88.7	1.3
Xanomeline Low Dose		Week 24	88.0	89.3	-1.3
Xanomeline Low Dose		Week 26	90.7	86.7	4.0
Xanomeline Low Dose		Week 26	92.0	88.7	3.3
Xanomeline Low Dose		Week 26	94.7	89.3	5.3
Xanomeline Low Dose		Week 4	88.0	86.7	1.3
Xanomeline Low Dose		Week 4	91.3	88.7	2.7
Xanomeline Low Dose		Week 4	85.3	89.3	-4.0
Xanomeline Low Dose		Week 6	95.3	86.7	8.7
Xanomeline Low Dose		Week 6	82.0	88.7	-6.7
Xanomeline Low Dose		Week 6	84.0	89.3	-5.3
Xanomeline Low Dose		Week 8	94.0	86.7	7.3
Xanomeline Low Dose		Week 8	91.3	88.7	2.7
Xanomeline Low Dose		Week 8	88.0	89.3	-1.3
Xanomeline Low Dose			98.7	86.7
Xanomeline Low Dose			98.0	88.7
Xanomeline Low Dose			94.7	89.3
Xanomeline Low Dose			90.7	86.7
Xanomeline Low Dose			86.7	88.7
Xanomeline Low Dose			84.0	89.3
Xanomeline High Dose		Week 12	96.7	98.7	-2.0
Xanomeline High Dose		Week 12	98.7	94.0	4.7
Xanomeline High Dose		Week 12	92.7	93.3	-0.7
Xanomeline High Dose		Week 16	97.3	98.7	-1.3
Xanomeline High Dose		Week 16	96.0	94.0	2.0
Xanomeline High Dose		Week 16	86.0	93.3	-7.3
Xanomeline High Dose		Week 2	88.7	98.7	-10.0
Xanomeline High Dose		Week 2	74.0	94.0	-20.0
Xanomeline High Dose		Week 2	74.0	93.3	-19.3
Xanomeline High Dose		Week 20	92.7	98.7	-6.0
Xanomeline High Dose		Week 20	80.7	94.0	-13.3
Xanomeline High Dose		Week 20	80.0	93.3	-13.3
Xanomeline High Dose		Week 24	92.7	98.7	-6.0
Xanomeline High Dose		Week 24	88.0	94.0	-6.0
Xanomeline High Dose		Week 24	87.3	93.3	-6.0
Xanomeline High Dose		Week 26	87.3	98.7	-11.3
Xanomeline High Dose		Week 26	81.3	94.0	-12.7
Xanomeline High Dose		Week 26	88.0	93.3	-5.3
Xanomeline High Dose		Week 4	86.0	98.7	-12.7
Xanomeline High Dose		Week 4	82.7	94.0	-11.3
Xanomeline High Dose		Week 4	80.7	93.3	-12.7
Xanomeline High Dose		Week 6	80.7	98.7	-18.0
Xanomeline High Dose		Week 6	74.0	94.0	-20.0
Xanomeline High Dose		Week 6	73.3	93.3	-20.0
Xanomeline High Dose		Week 8	94.7	98.7	-4.0
Xanomeline High Dose		Week 8	92.7	94.0	-1.3
Xanomeline High Dose		Week 8	90.3	93.3	-3.0
Xanomeline High Dose			84.7	98.7
Xanomeline High Dose			70.0	94.0
Xanomeline High Dose			82.7	93.3
Xanomeline High Dose			93.3	98.7
Xanomeline High Dose			89.3	94.0
Xanomeline High Dose			87.3	93.3
Xanomeline High Dose		Week 12	81.3	87.3	-6.0
Xanomeline High Dose		Week 12	82.0	88.0	-6.0
Xanomeline High Dose		Week 12	78.7	86.7	-8.0
Xanomeline High Dose		Week 16	87.3	87.3	0.0
Xanomeline High Dose		Week 16	85.3	88.0	-2.7
Xanomeline High Dose		Week 16	84.0	86.7	-2.7
Xanomeline High Dose		Week 2	84.0	87.3	-3.3
Xanomeline High Dose		Week 2	83.3	88.0	-4.7
Xanomeline High Dose		Week 2	82.0	86.7	-4.7
Xanomeline High Dose		Week 20	84.0	87.3	-3.3
Xanomeline High Dose		Week 20	76.7	88.0	-11.3
Xanomeline High Dose		Week 20	84.0	86.7	-2.7
Xanomeline High Dose		Week 24	79.3	87.3	-8.0
Xanomeline High Dose		Week 24	75.3	88.0	-12.7
Xanomeline High Dose		Week 24	84.7	86.7	-2.0
Xanomeline High Dose		Week 26	86.0	87.3	-1.3
Xanomeline High Dose		Week 26	88.7	88.0	0.7
Xanomeline High Dose		Week 26	81.3	86.7	-5.3
Xanomeline High Dose		Week 4	84.0	87.3	-3.3
Xanomeline High Dose		Week 4	80.7	88.0	-7.3
Xanomeline High Dose		Week 4	82.7	86.7	-4.0
Xanomeline High Dose		Week 6	93.3	87.3	6.0
Xanomeline High Dose		Week 6	95.3	88.0	7.3
Xanomeline High Dose		Week 6	93.3	86.7	6.7
Xanomeline High Dose		Week 8	92.7	87.3	5.3
Xanomeline High Dose		Week 8	95.3	88.0	7.3
Xanomeline High Dose		Week 8	90.7	86.7	4.0
Xanomeline High Dose			85.3	87.3
Xanomeline High Dose			83.3	88.0
Xanomeline High Dose			81.3	86.7
Placebo		Week 2	92.7	97.3	-4.7
Placebo		Week 2	90.0	94.0	-4.0
Placebo		Week 2	87.3	92.0	-4.7
Placebo		Week 4	96.0	97.3	-1.3
Placebo		Week 4	90.0	94.0	-4.0
Placebo		Week 4	92.0	92.0	0.0
Placebo		Week 6	96.0	97.3	-1.3
Placebo		Week 6	93.3	94.0	-0.7
Placebo		Week 6	91.3	92.0	-0.7
Placebo		Week 8	100.7	97.3	3.3
Placebo		Week 8	97.3	94.0	3.3
Placebo		Week 8	102.0	92.0	10.0
Placebo			101.3	97.3
Placebo			98.7	94.0
Placebo			95.3	92.0
Placebo			93.3	97.3
Placebo			90.7	94.0
Placebo			90.0	92.0
Placebo		Week 2	100.0	102.7	-2.7
Placebo		Week 2	96.0	100.0	-4.0
Placebo		Week 2	94.0	100.7	-6.7
Placebo		Week 4	102.7	102.7	0.0
Placebo		Week 4	103.3	100.0	3.3
Placebo		Week 4	106.0	100.7	5.3
Placebo		Week 6	88.0	102.7	-14.7
Placebo		Week 6	91.3	100.0	-8.7
Placebo		Week 6	88.7	100.7	-12.0
Placebo		Week 8	93.3	102.7	-9.3
Placebo		Week 8	95.3	100.0	-4.7
Placebo		Week 8	96.0	100.7	-4.7
Placebo			116.7	102.7
Placebo			110.7	100.0
Placebo			104.0	100.7
Placebo			100.0	102.7
Placebo			102.0	100.0
Placebo			100.7	100.7
Xanomeline High Dose		Week 12	82.0	83.3	-1.3
Xanomeline High Dose		Week 12	76.7	77.3	-0.7
Xanomeline High Dose		Week 12	84.0	84.7	-0.7
Xanomeline High Dose		Week 16	84.7	83.3	1.3
Xanomeline High Dose		Week 16	84.0	77.3	6.7
Xanomeline High Dose		Week 16	80.7	84.7	-4.0
Xanomeline High Dose		Week 2	84.7	83.3	1.3
Xanomeline High Dose		Week 2	87.3	77.3	10.0
Xanomeline High Dose		Week 2	89.3	84.7	4.7
Xanomeline High Dose		Week 20	86.7	83.3	3.3
Xanomeline High Dose		Week 20	85.0	77.3	7.7
Xanomeline High Dose		Week 20	94.7	84.7	10.0
Xanomeline High Dose		Week 4	92.7	83.3	9.3
Xanomeline High Dose		Week 4	89.3	77.3	12.0
Xanomeline High Dose		Week 4	91.3	84.7	6.7
Xanomeline High Dose		Week 6	73.3	83.3	-10.0
Xanomeline High Dose		Week 6	72.7	77.3	-4.7
Xanomeline High Dose		Week 6	79.3	84.7	-5.3
Xanomeline High Dose		Week 8	88.7	83.3	5.3
Xanomeline High Dose		Week 8	91.3	77.3	14.0
Xanomeline High Dose		Week 8	93.3	84.7	8.7
Xanomeline Low Dose		Week 12	102.0	94.0	8.0
Xanomeline Low Dose		Week 12	94.7	85.3	9.3
Xanomeline Low Dose		Week 12	102.0	84.7	17.3
Xanomeline Low Dose		Week 16	94.7	94.0	0.7
Xanomeline Low Dose		Week 16	104.0	85.3	18.7
Xanomeline Low Dose		Week 16	102.0	84.7	17.3
Xanomeline Low Dose		Week 2	108.0	94.0	14.0
Xanomeline Low Dose		Week 2	96.7	85.3	11.3
Xanomeline Low Dose		Week 2	93.3	84.7	8.7
Xanomeline Low Dose		Week 20	83.3	94.0	-10.7
Xanomeline Low Dose		Week 20	79.3	85.3	-6.0
Xanomeline Low Dose		Week 20	78.7	84.7	-6.0
Xanomeline Low Dose		Week 24	94.0	94.0	0.0
Xanomeline Low Dose		Week 24	105.3	85.3	20.0
Xanomeline Low Dose		Week 24	98.7	84.7	14.0
Xanomeline Low Dose		Week 4	92.7	94.0	-1.3
Xanomeline Low Dose		Week 4	88.0	85.3	2.7
Xanomeline Low Dose		Week 4	87.3	84.7	2.7
Xanomeline Low Dose		Week 6	96.0	94.0	2.0
Xanomeline Low Dose		Week 6	94.0	85.3	8.7
Xanomeline Low Dose		Week 6	93.3	84.7	8.7
Xanomeline Low Dose		Week 8	108.0	94.0	14.0
Xanomeline Low Dose		Week 8	111.3	85.3	26.0
Xanomeline Low Dose		Week 8	109.3	84.7	24.7
Xanomeline Low Dose			103.3	94.0
Xanomeline Low Dose			100.0	85.3
Xanomeline Low Dose			99.3	84.7
Xanomeline Low Dose			90.7	94.0
Xanomeline Low Dose			88.7	85.3
Xanomeline Low Dose			86.7	84.7
Xanomeline Low Dose		Week 2	84.3	96.3	-12.0
Xanomeline Low Dose		Week 2	88.3	94.7	-6.3
Xanomeline Low Dose		Week 2	87.0	97.0	-10.0
Xanomeline Low Dose		Week 4	81.7	96.3	-14.7
Xanomeline Low Dose		Week 4	89.7	94.7	-5.0
Xanomeline Low Dose		Week 4	95.0	97.0	-2.0
Xanomeline Low Dose			102.0	96.3
Xanomeline Low Dose			110.3	94.7
Xanomeline Low Dose			112.0	97.0
Xanomeline Low Dose			86.0	96.3
Xanomeline Low Dose			92.3	94.7
Xanomeline Low Dose			101.0	97.0
Xanomeline High Dose		Week 12	86.3	89.3	-3.0
Xanomeline High Dose		Week 12	93.3	100.0	-6.7
Xanomeline High Dose		Week 12	97.0	96.3	0.7
Xanomeline High Dose		Week 16	87.7	89.3	-1.7
Xanomeline High Dose		Week 16	91.7	100.0	-8.3
Xanomeline High Dose		Week 16	91.3	96.3	-5.0
Xanomeline High Dose		Week 2	95.7	89.3	6.3
Xanomeline High Dose		Week 2	92.0	100.0	-8.0
Xanomeline High Dose		Week 2	102.0	96.3	5.7
Xanomeline High Dose		Week 20	87.0	89.3	-2.3
Xanomeline High Dose		Week 20	89.0	100.0	-11.0
Xanomeline High Dose		Week 20	86.0	96.3	-10.3
Xanomeline High Dose		Week 4	91.7	89.3	2.3
Xanomeline High Dose		Week 4	91.7	100.0	-8.3
Xanomeline High Dose		Week 4	96.3	96.3	0.0
Xanomeline High Dose		Week 6	86.3	89.3	-3.0
Xanomeline High Dose		Week 6	91.3	100.0	-8.7
Xanomeline High Dose		Week 6	91.3	96.3	-5.0
Xanomeline High Dose		Week 8	81.0	89.3	-8.3
Xanomeline High Dose		Week 8	87.3	100.0	-12.7
Xanomeline High Dose		Week 8	93.3	96.3	-3.0
Xanomeline High Dose			84.7	89.3
Xanomeline High Dose			94.7	100.0
Xanomeline High Dose			94.0	96.3
Xanomeline High Dose			79.0	89.3
Xanomeline High Dose			92.3	100.0
Xanomeline High Dose			88.7	96.3
Placebo		Week 12	92.7	98.7	-6.0
Placebo		Week 12	93.3	108.3	-15.0
Placebo		Week 12	103.7	109.3	-5.7
Placebo		Week 16	95.3	98.7	-3.3
Placebo		Week 16	107.3	108.3	-1.0
Placebo		Week 16	103.7	109.3	-5.7
Placebo		Week 2	104.0	98.7	5.3
Placebo		Week 2	106.7	108.3	-1.7
Placebo		Week 2	110.0	109.3	0.7
Placebo		Week 20	100.0	98.7	1.3
Placebo		Week 20	100.7	108.3	-7.7
Placebo		Week 20	92.3	109.3	-17.0
Placebo		Week 24	101.3	98.7	2.7
Placebo		Week 24	99.0	108.3	-9.3
Placebo		Week 24	96.7	109.3	-12.7
Placebo		Week 26	95.7	98.7	-3.0
Placebo		Week 26	94.7	108.3	-13.7
Placebo		Week 26	97.0	109.3	-12.3
Placebo		Week 4	92.0	98.7	-6.7
Placebo		Week 4	97.7	108.3	-10.7
Placebo		Week 4	95.0	109.3	-14.3
Placebo		Week 6	80.7	98.7	-18.0
Placebo		Week 6	106.0	108.3	-2.3
Placebo		Week 6	94.0	109.3	-15.3
Placebo		Week 8	95.0	98.7	-3.7
Placebo		Week 8	107.3	108.3	-1.0
Placebo		Week 8	100.3	109.3	-9.0
Placebo			105.7	98.7
Placebo			104.7	108.3
Placebo			111.0	109.3
Placebo			86.0	98.7
Placebo			95.0	108.3
Placebo			99.7	109.3
Placebo		Week 12	99.0	96.0	3.0
Placebo		Week 12	100.7	109.0	-8.3
Placebo		Week 12	100.7	105.0	-4.3
Placebo		Week 16	86.0	96.0	-10.0
Placebo		Week 16	85.0	109.0	-24.0
Placebo		Week 16	88.3	105.0	-16.7
Placebo		Week 2	92.3	96.0	-3.7
Placebo		Week 2	102.0	109.0	-7.0
Placebo		Week 2	84.0	105.0	-21.0
Placebo		Week 20	90.7	96.0	-5.3
Placebo		Week 20	105.7	109.0	-3.3
Placebo		Week 20	100.3	105.0	-4.7
Placebo		Week 24	81.7	96.0	-14.3
Placebo		Week 24	84.0	109.0	-25.0
Placebo		Week 24	88.0	105.0	-17.0
Placebo		Week 4	96.0	96.0	0.0
Placebo		Week 4	89.7	109.0	-19.3
Placebo		Week 4	95.7	105.0	-9.3
Placebo		Week 6	88.7	96.0	-7.3
Placebo		Week 6	94.7	109.0	-14.3
Placebo		Week 6	89.3	105.0	-15.7
Placebo		Week 8	98.7	96.0	2.7
Placebo		Week 8	92.7	109.0	-16.3
Placebo		Week 8	91.3	105.0	-13.7
Placebo			102.7	96.0
Placebo			105.3	109.0
Placebo			102.7	105.0
Placebo			108.0	96.0
Placebo			113.3	109.0
Placebo			113.3	105.0
Xanomeline Low Dose		Week 2	124.7	108.0	16.7
Xanomeline Low Dose		Week 2	110.0	102.0	8.0
Xanomeline Low Dose		Week 2	112.0	97.7	14.3
Xanomeline Low Dose			106.0	108.0
Xanomeline Low Dose			108.7	102.0
Xanomeline Low Dose			111.3	97.7
Placebo		Week 12	120.3	115.0	5.3
Placebo		Week 12	113.3	106.7	6.7
Placebo		Week 12	120.7	117.3	3.3
Placebo		Week 2	113.3	115.0	-1.7
Placebo		Week 2	119.3	106.7	12.7
Placebo		Week 2	116.0	117.3	-1.3
Placebo		Week 4	108.0	115.0	-7.0
Placebo		Week 4	114.7	106.7	8.0
Placebo		Week 4	109.7	117.3	-7.7
Placebo		Week 6	102.7	115.0	-12.3
Placebo		Week 6	100.0	106.7	-6.7
Placebo		Week 6	100.7	117.3	-16.7
Placebo		Week 8	103.3	115.0	-11.7
Placebo		Week 8	101.7	106.7	-5.0
Placebo		Week 8	110.0	117.3	-7.3
Placebo			107.7	115.0
Placebo			101.7	106.7
Placebo			112.3	117.3
Placebo			95.3	115.0
Placebo			102.0	106.7
Placebo			101.7	117.3
Xanomeline Low Dose		Week 12	85.3	80.0	5.3
Xanomeline Low Dose		Week 12	79.3	84.0	-4.7
Xanomeline Low Dose		Week 12	87.3	81.0	6.3
Xanomeline Low Dose		Week 16	78.0	80.0	-2.0
Xanomeline Low Dose		Week 16	74.3	84.0	-9.7
Xanomeline Low Dose		Week 16	72.7	81.0	-8.3
Xanomeline Low Dose		Week 2	90.7	80.0	10.7
Xanomeline Low Dose		Week 2	88.7	84.0	4.7
Xanomeline Low Dose		Week 2	87.0	81.0	6.0
Xanomeline Low Dose		Week 4	77.0	80.0	-3.0
Xanomeline Low Dose		Week 4	78.0	84.0	-6.0
Xanomeline Low Dose		Week 4	78.0	81.0	-3.0
Xanomeline Low Dose		Week 6	80.7	80.0	0.7
Xanomeline Low Dose		Week 6	83.3	84.0	-0.7
Xanomeline Low Dose		Week 6	72.7	81.0	-8.3
Xanomeline Low Dose		Week 8	86.3	80.0	6.3
Xanomeline Low Dose		Week 8	83.7	84.0	-0.3
Xanomeline Low Dose		Week 8	82.0	81.0	1.0
Xanomeline Low Dose			86.7	80.0
Xanomeline Low Dose			85.3	84.0
Xanomeline Low Dose			82.0	81.0
Xanomeline Low Dose			78.0	80.0
Xanomeline Low Dose			76.0	84.0
Xanomeline Low Dose			78.0	81.0
Xanomeline Low Dose		Week 12	91.7	117.3	-25.7
Xanomeline Low Dose		Week 12	96.7	96.3	0.3
Xanomeline Low Dose		Week 12	90.0	84.7	5.3
Xanomeline Low Dose		Week 16	91.0	117.3	-26.3
Xanomeline Low Dose		Week 16	90.3	96.3	-6.0
Xanomeline Low Dose		Week 16	86.3	84.7	1.7
Xanomeline Low Dose		Week 2	86.0	117.3	-31.3
Xanomeline Low Dose		Week 2	87.3	96.3	-9.0
Xanomeline Low Dose		Week 2	88.7	84.7	4.0
Xanomeline Low Dose		Week 20	97.7	117.3	-19.7
Xanomeline Low Dose		Week 20	93.0	96.3	-3.3
Xanomeline Low Dose		Week 20	91.7	84.7	7.0
Xanomeline Low Dose		Week 24	96.0	117.3	-21.3
Xanomeline Low Dose		Week 24	92.3	96.3	-4.0
Xanomeline Low Dose		Week 24	87.7	84.7	3.0
Xanomeline Low Dose		Week 26	94.3	117.3	-23.0
Xanomeline Low Dose		Week 26	100.7	96.3	4.3
Xanomeline Low Dose		Week 26	100.0	84.7	15.3
Xanomeline Low Dose		Week 4	93.7	117.3	-23.7
Xanomeline Low Dose		Week 4	83.0	96.3	-13.3
Xanomeline Low Dose		Week 4	92.7	84.7	8.0
Xanomeline Low Dose		Week 6	79.7	117.3	-37.7
Xanomeline Low Dose		Week 6	88.7	96.3	-7.7
Xanomeline Low Dose		Week 6	87.0	84.7	2.3
Xanomeline Low Dose		Week 8	88.7	117.3	-28.7
Xanomeline Low Dose		Week 8	85.7	96.3	-10.7
Xanomeline Low Dose		Week 8	86.3	84.7	1.7
Xanomeline Low Dose			100.7	117.3
Xanomeline Low Dose			92.0	96.3
Xanomeline Low Dose			94.0	84.7
Xanomeline Low Dose			88.7	117.3
Xanomeline Low Dose			81.3	96.3
Xanomeline Low Dose			79.0	84.7
Xanomeline High Dose		Week 2	99.3	95.0	4.3
Xanomeline High Dose		Week 2	94.0	89.0	5.0
Xanomeline High Dose		Week 2	86.0	97.7	-11.7
Xanomeline High Dose		Week 4	84.3	95.0	-10.7
Xanomeline High Dose		Week 4	74.7	89.0	-14.3
Xanomeline High Dose		Week 4	82.0	97.7	-15.7
Xanomeline High Dose		Week 6	95.3	95.0	0.3
Xanomeline High Dose		Week 6	91.3	89.0	2.3
Xanomeline High Dose		Week 6	90.3	97.7	-7.3
Xanomeline High Dose		Week 8	86.0	95.0	-9.0
Xanomeline High Dose		Week 8	97.0	89.0	8.0
Xanomeline High Dose		Week 8	82.3	97.7	-15.3
Xanomeline High Dose			90.0	95.0
Xanomeline High Dose			95.0	89.0
Xanomeline High Dose			95.0	97.7
Placebo		Week 12	102.3	95.3	7.0
Placebo		Week 12	95.3	115.0	-19.7
Placebo		Week 12	104.7	102.3	2.3
Placebo		Week 16	105.3	95.3	10.0
Placebo		Week 16	109.0	115.0	-6.0
Placebo		Week 16	104.0	102.3	1.7
Placebo		Week 2	98.7	95.3	3.3
Placebo		Week 2	119.0	115.0	4.0
Placebo		Week 2	113.0	102.3	10.7
Placebo		Week 20	103.0	95.3	7.7
Placebo		Week 20	98.3	115.0	-16.7
Placebo		Week 20	102.0	102.3	-0.3
Placebo		Week 24	131.3	95.3	36.0
Placebo		Week 24	144.3	115.0	29.3
Placebo		Week 24	126.0	102.3	23.7
Placebo		Week 26	90.7	95.3	-4.7
Placebo		Week 26	86.0	115.0	-29.0
Placebo		Week 26	93.0	102.3	-9.3
Placebo		Week 4	123.3	95.3	28.0
Placebo		Week 4	131.3	115.0	16.3
Placebo		Week 4	121.7	102.3	19.3
Placebo		Week 6	123.7	95.3	28.3
Placebo		Week 6	122.0	115.0	7.0
Placebo		Week 6	124.3	102.3	22.0
Placebo		Week 8	123.7	95.3	28.3
Placebo		Week 8	128.3	115.0	13.3
Placebo		Week 8	125.7	102.3	23.3
Placebo			117.3	95.3
Placebo			112.0	115.0
Placebo			108.0	102.3
Placebo			110.0	95.3
Placebo			110.0	115.0
Placebo			110.0	102.3
Xanomeline High Dose		Week 2	97.3	83.3	14.0
Xanomeline High Dose		Week 2	100.7	90.0	10.7
Xanomeline High Dose		Week 2	91.3	120.0	-28.7
Xanomeline High Dose		Week 4	86.3	83.3	3.0
Xanomeline High Dose		Week 4	96.7	90.0	6.7
Xanomeline High Dose		Week 4	103.3	120.0	-16.7
Xanomeline High Dose		Week 6	78.3	83.3	-5.0
Xanomeline High Dose		Week 6	80.3	90.0	-9.7
Xanomeline High Dose		Week 6	77.0	120.0	-43.0
Xanomeline High Dose		Week 8	89.7	83.3	6.3
Xanomeline High Dose		Week 8	88.7	90.0	-1.3
Xanomeline High Dose		Week 8	88.0	120.0	-32.0
Xanomeline High Dose			80.3	83.3
Xanomeline High Dose			93.7	90.0
Xanomeline High Dose			87.0	120.0
Xanomeline High Dose			90.3	120.0
Xanomeline High Dose		Week 2	94.0	103.7	-9.7
Xanomeline High Dose		Week 2	96.7	101.7	-5.0
Xanomeline High Dose		Week 2	95.0	97.7	-2.7
Xanomeline High Dose		Week 4	105.0	103.7	1.3
Xanomeline High Dose		Week 4	101.3	101.7	-0.3
Xanomeline High Dose		Week 4	106.7	97.7	9.0
Xanomeline High Dose		Week 6	114.7	103.7	11.0
Xanomeline High Dose		Week 6	106.0	101.7	4.3
Xanomeline High Dose		Week 6	112.3	97.7	14.7
Xanomeline High Dose			101.3	103.7
Xanomeline High Dose			98.0	101.7
Xanomeline High Dose			94.0	97.7
Xanomeline High Dose			86.3	103.7
Xanomeline High Dose			94.0	101.7
Xanomeline High Dose			102.0	97.7

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

PULSE

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	54.0	56.0	-2.0
Placebo		Week 12	53.0	59.0	-6.0
Placebo		Week 12	52.0	59.0	-7.0
Placebo		Week 16	60.0	56.0	4.0
Placebo		Week 16	55.0	59.0	-4.0
Placebo		Week 16	61.0	59.0	2.0
Placebo		Week 2	58.0	56.0	2.0
Placebo		Week 2	61.0	59.0	2.0
Placebo		Week 2	62.0	59.0	3.0
Placebo		Week 20	54.0	56.0	-2.0
Placebo		Week 20	59.0	59.0	0.0
Placebo		Week 20	58.0	59.0	-1.0
Placebo		Week 24	55.0	56.0	-1.0
Placebo		Week 24	57.0	59.0	-2.0
Placebo		Week 24	56.0	59.0	-3.0
Placebo		Week 26	60.0	56.0	4.0
Placebo		Week 26	61.0	59.0	2.0
Placebo		Week 26	59.0	59.0	0.0
Placebo		Week 4	59.0	56.0	3.0
Placebo		Week 4	62.0	59.0	3.0
Placebo		Week 4	59.0	59.0	0.0
Placebo		Week 6	55.0	56.0	-1.0
Placebo		Week 6	56.0	59.0	-3.0
Placebo		Week 6	57.0	59.0	-2.0
Placebo		Week 8	57.0	56.0	1.0
Placebo		Week 8	60.0	59.0	1.0
Placebo		Week 8	57.0	59.0	-2.0
Placebo			61.0	56.0
Placebo			65.0	59.0
Placebo			61.0	59.0
Placebo			67.0	56.0
Placebo			69.0	59.0
Placebo			65.0	59.0
Placebo		Week 2	84.0	68.0	16.0
Placebo		Week 2	92.0	80.0	12.0
Placebo		Week 2	94.0	76.0	18.0
Placebo			71.0	68.0
Placebo			79.0	80.0
Placebo			77.0	76.0
Xanomeline High Dose		Week 12	61.0	62.0	-1.0
Xanomeline High Dose		Week 12	64.0	62.0	2.0
Xanomeline High Dose		Week 12	70.0	66.0	4.0
Xanomeline High Dose		Week 16	60.0	62.0	-2.0
Xanomeline High Dose		Week 16	70.0	62.0	8.0
Xanomeline High Dose		Week 16	69.0	66.0	3.0
Xanomeline High Dose		Week 2	65.0	62.0	3.0
Xanomeline High Dose		Week 2	77.0	62.0	15.0
Xanomeline High Dose		Week 2	72.0	66.0	6.0
Xanomeline High Dose		Week 20	60.0	62.0	-2.0
Xanomeline High Dose		Week 20	67.0	62.0	5.0
Xanomeline High Dose		Week 20	69.0	66.0	3.0
Xanomeline High Dose		Week 24	62.0	62.0	0.0
Xanomeline High Dose		Week 24	72.0	62.0	10.0
Xanomeline High Dose		Week 24	73.0	66.0	7.0
Xanomeline High Dose		Week 26	53.0	62.0	-9.0
Xanomeline High Dose		Week 26	58.0	62.0	-4.0
Xanomeline High Dose		Week 26	59.0	66.0	-7.0
Xanomeline High Dose		Week 4	68.0	62.0	6.0
Xanomeline High Dose		Week 4	81.0	62.0	19.0
Xanomeline High Dose		Week 4	76.0	66.0	10.0
Xanomeline High Dose		Week 6	56.0	62.0	-6.0
Xanomeline High Dose		Week 6	60.0	62.0	-2.0
Xanomeline High Dose		Week 6	62.0	66.0	-4.0
Xanomeline High Dose		Week 8	67.0	62.0	5.0
Xanomeline High Dose		Week 8	76.0	62.0	14.0
Xanomeline High Dose		Week 8	81.0	66.0	15.0
Xanomeline High Dose			60.0	62.0
Xanomeline High Dose			66.0	62.0
Xanomeline High Dose			65.0	66.0
Xanomeline High Dose			63.0	62.0
Xanomeline High Dose			68.0	62.0
Xanomeline High Dose			70.0	66.0
Xanomeline Low Dose			62.0	55.0
Xanomeline Low Dose			62.0	64.0
Xanomeline Low Dose			60.0	62.0
Xanomeline High Dose		Week 12	66.0	76.0	-10.0
Xanomeline High Dose		Week 12	70.0	83.0	-13.0
Xanomeline High Dose		Week 12	69.0	80.0	-11.0
Xanomeline High Dose		Week 16	74.0	76.0	-2.0
Xanomeline High Dose		Week 16	79.0	83.0	-4.0
Xanomeline High Dose		Week 16	78.0	80.0	-2.0
Xanomeline High Dose		Week 2	86.0	76.0	10.0
Xanomeline High Dose		Week 2	91.0	83.0	8.0
Xanomeline High Dose		Week 2	86.0	80.0	6.0
Xanomeline High Dose		Week 20	86.0	76.0	10.0
Xanomeline High Dose		Week 20	84.0	83.0	1.0
Xanomeline High Dose		Week 20	80.0	80.0	0.0
Xanomeline High Dose		Week 24	96.0	76.0	20.0
Xanomeline High Dose		Week 24	97.0	83.0	14.0
Xanomeline High Dose		Week 24	91.0	80.0	11.0
Xanomeline High Dose		Week 26	74.0	76.0	-2.0
Xanomeline High Dose		Week 26	86.0	83.0	3.0
Xanomeline High Dose		Week 26	76.0	80.0	-4.0
Xanomeline High Dose		Week 4	87.0	76.0	11.0
Xanomeline High Dose		Week 4	91.0	83.0	8.0
Xanomeline High Dose		Week 4	88.0	80.0	8.0
Xanomeline High Dose		Week 6	97.0	76.0	21.0
Xanomeline High Dose		Week 6	93.0	83.0	10.0
Xanomeline High Dose		Week 6	94.0	80.0	14.0
Xanomeline High Dose		Week 8	78.0	76.0	2.0
Xanomeline High Dose		Week 8	71.0	83.0	-12.0
Xanomeline High Dose		Week 8	71.0	80.0	-9.0
Xanomeline High Dose			83.0	76.0
Xanomeline High Dose			90.0	83.0
Xanomeline High Dose			86.0	80.0
Placebo		Week 2	66.0	58.0	8.0
Placebo		Week 2	75.0	67.0	8.0
Placebo		Week 2	78.0	67.0	11.0
Placebo			62.0	58.0
Placebo			74.0	67.0
Placebo			72.0	67.0
Xanomeline Low Dose		Week 12	58.0	60.0	-2.0
Xanomeline Low Dose		Week 12	72.0	68.0	4.0
Xanomeline Low Dose		Week 12	70.0	64.0	6.0
Xanomeline Low Dose		Week 16	67.0	60.0	7.0
Xanomeline Low Dose		Week 16	74.0	68.0	6.0
Xanomeline Low Dose		Week 16	72.0	64.0	8.0
Xanomeline Low Dose		Week 2	66.0	60.0	6.0
Xanomeline Low Dose		Week 2	72.0	68.0	4.0
Xanomeline Low Dose		Week 2	68.0	64.0	4.0
Xanomeline Low Dose		Week 20	61.0	60.0	1.0
Xanomeline Low Dose		Week 20	70.0	68.0	2.0
Xanomeline Low Dose		Week 20	67.0	64.0	3.0
Xanomeline Low Dose		Week 24	65.0	60.0	5.0
Xanomeline Low Dose		Week 24	74.0	68.0	6.0
Xanomeline Low Dose		Week 24	72.0	64.0	8.0
Xanomeline Low Dose		Week 26	58.0	60.0	-2.0
Xanomeline Low Dose		Week 26	76.0	68.0	8.0
Xanomeline Low Dose		Week 26	66.0	64.0	2.0
Xanomeline Low Dose		Week 4	50.0	60.0	-10.0
Xanomeline Low Dose		Week 4	54.0	68.0	-14.0
Xanomeline Low Dose		Week 4	54.0	64.0	-10.0
Xanomeline Low Dose		Week 6	64.0	60.0	4.0
Xanomeline Low Dose		Week 6	76.0	68.0	8.0
Xanomeline Low Dose		Week 6	74.0	64.0	10.0
Xanomeline Low Dose		Week 8	54.0	60.0	-6.0
Xanomeline Low Dose		Week 8	62.0	68.0	-6.0
Xanomeline Low Dose		Week 8	61.0	64.0	-3.0
Xanomeline Low Dose			55.0	60.0
Xanomeline Low Dose			59.0	68.0
Xanomeline Low Dose			60.0	64.0
Xanomeline Low Dose			62.0	60.0
Xanomeline Low Dose			68.0	68.0
Xanomeline Low Dose			66.0	64.0
Xanomeline Low Dose		Week 2	53.0	50.0	3.0
Xanomeline Low Dose		Week 2	70.0	62.0	8.0
Xanomeline Low Dose		Week 2	65.0	60.0	5.0
Xanomeline Low Dose		Week 4	51.0	50.0	1.0
Xanomeline Low Dose		Week 4	57.0	62.0	-5.0
Xanomeline Low Dose		Week 4	64.0	60.0	4.0
Xanomeline Low Dose		Week 6	52.0	50.0	2.0
Xanomeline Low Dose		Week 6	62.0	62.0	0.0
Xanomeline Low Dose		Week 6	62.0	60.0	2.0
Xanomeline Low Dose		Week 8	50.0	50.0	0.0
Xanomeline Low Dose		Week 8	52.0	62.0	-10.0
Xanomeline Low Dose		Week 8	54.0	60.0	-6.0
Xanomeline Low Dose			52.0	50.0
Xanomeline Low Dose			64.0	62.0
Xanomeline Low Dose			65.0	60.0
Xanomeline Low Dose			50.0	50.0
Xanomeline Low Dose			63.0	62.0
Xanomeline Low Dose			60.0	60.0
Placebo		Week 12	75.0	62.0	13.0
Placebo		Week 12	89.0	70.0	19.0
Placebo		Week 12	89.0	70.0	19.0
Placebo		Week 16	70.0	62.0	8.0
Placebo		Week 16	78.0	70.0	8.0
Placebo		Week 16	78.0	70.0	8.0
Placebo		Week 2	62.0	62.0	0.0
Placebo		Week 2	73.0	70.0	3.0
Placebo		Week 2	68.0	70.0	-2.0
Placebo		Week 20	72.0	62.0	10.0
Placebo		Week 20	87.0	70.0	17.0
Placebo		Week 20	85.0	70.0	15.0
Placebo		Week 24	61.0	62.0	-1.0
Placebo		Week 24	74.0	70.0	4.0
Placebo		Week 24	75.0	70.0	5.0
Placebo		Week 26	65.0	62.0	3.0
Placebo		Week 26	75.0	70.0	5.0
Placebo		Week 26	75.0	70.0	5.0
Placebo		Week 4	64.0	62.0	2.0
Placebo		Week 4	72.0	70.0	2.0
Placebo		Week 4	81.0	70.0	11.0
Placebo		Week 6	74.0	62.0	12.0
Placebo		Week 6	77.0	70.0	7.0
Placebo		Week 6	79.0	70.0	9.0
Placebo		Week 8	65.0	62.0	3.0
Placebo		Week 8	83.0	70.0	13.0
Placebo		Week 8	80.0	70.0	10.0
Placebo			59.0	62.0
Placebo			72.0	70.0
Placebo			68.0	70.0
Placebo			67.0	62.0
Placebo			81.0	70.0
Placebo			84.0	70.0
Placebo		Week 12	68.0	70.0	-2.0
Placebo		Week 12	75.0	77.0	-2.0
Placebo		Week 12	74.0	76.0	-2.0
Placebo		Week 16	65.0	70.0	-5.0
Placebo		Week 16	72.0	77.0	-5.0
Placebo		Week 16	72.0	76.0	-4.0
Placebo		Week 2	68.0	70.0	-2.0
Placebo		Week 2	76.0	77.0	-1.0
Placebo		Week 2	72.0	76.0	-4.0
Placebo		Week 20	74.0	70.0	4.0
Placebo		Week 20	83.0	77.0	6.0
Placebo		Week 20	80.0	76.0	4.0
Placebo		Week 24	60.0	70.0	-10.0
Placebo		Week 24	76.0	77.0	-1.0
Placebo		Week 24	74.0	76.0	-2.0
Placebo		Week 26	63.0	70.0	-7.0
Placebo		Week 26	76.0	77.0	-1.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 4	74.0	70.0	4.0
Placebo		Week 4	80.0	77.0	3.0
Placebo		Week 4	79.0	76.0	3.0
Placebo		Week 6	60.0	70.0	-10.0
Placebo		Week 6	72.0	77.0	-5.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 8	70.0	70.0	0.0
Placebo		Week 8	76.0	77.0	-1.0
Placebo		Week 8	75.0	76.0	-1.0
Placebo			65.0	70.0
Placebo			70.0	77.0
Placebo			68.0	76.0
Placebo			69.0	70.0
Placebo			78.0	77.0
Placebo			82.0	76.0
Xanomeline High Dose		Week 12	79.0	70.0	9.0
Xanomeline High Dose		Week 12	88.0	73.0	15.0
Xanomeline High Dose		Week 12	82.0	64.0	18.0
Xanomeline High Dose		Week 16	70.0	70.0	0.0
Xanomeline High Dose		Week 16	72.0	73.0	-1.0
Xanomeline High Dose		Week 16	74.0	64.0	10.0
Xanomeline High Dose		Week 2	59.0	70.0	-11.0
Xanomeline High Dose		Week 2	64.0	73.0	-9.0
Xanomeline High Dose		Week 2	66.0	64.0	2.0
Xanomeline High Dose		Week 20	77.0	70.0	7.0
Xanomeline High Dose		Week 20	81.0	73.0	8.0
Xanomeline High Dose		Week 20	80.0	64.0	16.0
Xanomeline High Dose		Week 24	57.0	70.0	-13.0
Xanomeline High Dose		Week 24	61.0	73.0	-12.0
Xanomeline High Dose		Week 24	57.0	64.0	-7.0
Xanomeline High Dose		Week 4	64.0	70.0	-6.0
Xanomeline High Dose		Week 4	68.0	73.0	-5.0
Xanomeline High Dose		Week 4	61.0	64.0	-3.0
Xanomeline High Dose		Week 6	63.0	70.0	-7.0
Xanomeline High Dose		Week 6	61.0	73.0	-12.0
Xanomeline High Dose		Week 6	62.0	64.0	-2.0
Xanomeline High Dose		Week 8	57.0	70.0	-13.0
Xanomeline High Dose		Week 8	61.0	73.0	-12.0
Xanomeline High Dose		Week 8	62.0	64.0	-2.0
Xanomeline High Dose			65.0	70.0
Xanomeline High Dose			74.0	73.0
Xanomeline High Dose			75.0	64.0
Xanomeline High Dose			66.0	70.0
Xanomeline High Dose			67.0	73.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose		Week 2	62.0	67.0	-5.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	69.0	68.0	1.0
Xanomeline High Dose		Week 4	68.0	67.0	1.0
Xanomeline High Dose		Week 4	73.0	72.0	1.0
Xanomeline High Dose		Week 4	73.0	68.0	5.0
Xanomeline High Dose			65.0	67.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			67.0	68.0
Xanomeline High Dose			68.0	67.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			72.0	68.0
Xanomeline High Dose		Week 12	57.0	58.0	-1.0
Xanomeline High Dose		Week 12	65.0	73.0	-8.0
Xanomeline High Dose		Week 12	70.0	70.0	0.0
Xanomeline High Dose		Week 16	60.0	58.0	2.0
Xanomeline High Dose		Week 16	78.0	73.0	5.0
Xanomeline High Dose		Week 16	77.0	70.0	7.0
Xanomeline High Dose		Week 2	74.0	58.0	16.0
Xanomeline High Dose		Week 2	86.0	73.0	13.0
Xanomeline High Dose		Week 2	81.0	70.0	11.0
Xanomeline High Dose		Week 20	52.0	58.0	-6.0
Xanomeline High Dose		Week 20	59.0	73.0	-14.0
Xanomeline High Dose		Week 20	59.0	70.0	-11.0
Xanomeline High Dose		Week 24	59.0	58.0	1.0
Xanomeline High Dose		Week 24	74.0	73.0	1.0
Xanomeline High Dose		Week 24	76.0	70.0	6.0
Xanomeline High Dose		Week 26	62.0	58.0	4.0
Xanomeline High Dose		Week 26	77.0	73.0	4.0
Xanomeline High Dose		Week 26	75.0	70.0	5.0
Xanomeline High Dose		Week 4	72.0	58.0	14.0
Xanomeline High Dose		Week 4	83.0	73.0	10.0
Xanomeline High Dose		Week 4	84.0	70.0	14.0
Xanomeline High Dose		Week 6	61.0	58.0	3.0
Xanomeline High Dose		Week 6	73.0	73.0	0.0
Xanomeline High Dose		Week 6	74.0	70.0	4.0
Xanomeline High Dose		Week 8	70.0	58.0	12.0
Xanomeline High Dose		Week 8	80.0	73.0	7.0
Xanomeline High Dose		Week 8	77.0	70.0	7.0
Xanomeline High Dose			75.0	58.0
Xanomeline High Dose			80.0	73.0
Xanomeline High Dose			80.0	70.0
Xanomeline High Dose			70.0	58.0
Xanomeline High Dose			76.0	73.0
Xanomeline High Dose			77.0	70.0
Placebo		Week 12	80.0	84.0	-4.0
Placebo		Week 12	84.0	89.0	-5.0
Placebo		Week 12	86.0	86.0	0.0
Placebo		Week 16	74.0	84.0	-10.0
Placebo		Week 16	74.0	89.0	-15.0
Placebo		Week 16	76.0	86.0	-10.0
Placebo		Week 2	72.0	84.0	-12.0
Placebo		Week 2	74.0	89.0	-15.0
Placebo		Week 2	79.0	86.0	-7.0
Placebo		Week 20	68.0	84.0	-16.0
Placebo		Week 20	68.0	89.0	-21.0
Placebo		Week 20	71.0	86.0	-15.0
Placebo		Week 24	74.0	84.0	-10.0
Placebo		Week 24	77.0	89.0	-12.0
Placebo		Week 24	79.0	86.0	-7.0
Placebo		Week 4	76.0	84.0	-8.0
Placebo		Week 4	75.0	89.0	-14.0
Placebo		Week 4	78.0	86.0	-8.0
Placebo		Week 6	66.0	84.0	-18.0
Placebo		Week 6	78.0	89.0	-11.0
Placebo		Week 6	72.0	86.0	-14.0
Placebo		Week 8	74.0	84.0	-10.0
Placebo		Week 8	80.0	89.0	-9.0
Placebo		Week 8	78.0	86.0	-8.0
Placebo			82.0	84.0
Placebo			88.0	89.0
Placebo			86.0	86.0
Placebo			70.0	84.0
Placebo			76.0	89.0
Placebo			74.0	86.0
Xanomeline High Dose		Week 2	68.0	66.0	2.0
Xanomeline High Dose		Week 2	74.0	74.0	0.0
Xanomeline High Dose		Week 2	74.0	70.0	4.0
Xanomeline High Dose		Week 4	67.0	66.0	1.0
Xanomeline High Dose		Week 4	81.0	74.0	7.0
Xanomeline High Dose		Week 4	71.0	70.0	1.0
Xanomeline High Dose			71.0	66.0
Xanomeline High Dose			77.0	74.0
Xanomeline High Dose			78.0	70.0
Xanomeline High Dose			61.0	66.0
Xanomeline High Dose			72.0	74.0
Xanomeline High Dose			70.0	70.0
Xanomeline Low Dose		Week 2	61.0	57.0	4.0
Xanomeline Low Dose		Week 2	64.0	65.0	-1.0
Xanomeline Low Dose		Week 2	67.0	56.0	11.0
Xanomeline Low Dose		Week 4	63.0	57.0	6.0
Xanomeline Low Dose		Week 4	68.0	65.0	3.0
Xanomeline Low Dose		Week 4	68.0	56.0	12.0
Xanomeline Low Dose			66.0	57.0
Xanomeline Low Dose			76.0	65.0
Xanomeline Low Dose			70.0	56.0
Xanomeline Low Dose			59.0	57.0
Xanomeline Low Dose			64.0	65.0
Xanomeline Low Dose			65.0	56.0
Xanomeline Low Dose		Week 12	85.0	74.0	11.0
Xanomeline Low Dose		Week 12	94.0	86.0	8.0
Xanomeline Low Dose		Week 12	91.0	82.0	9.0
Xanomeline Low Dose		Week 16	72.0	74.0	-2.0
Xanomeline Low Dose		Week 16	84.0	86.0	-2.0
Xanomeline Low Dose		Week 16	86.0	82.0	4.0
Xanomeline Low Dose		Week 2	67.0	74.0	-7.0
Xanomeline Low Dose		Week 2	75.0	86.0	-11.0
Xanomeline Low Dose		Week 2	86.0	82.0	4.0
Xanomeline Low Dose		Week 20	60.0	74.0	-14.0
Xanomeline Low Dose		Week 20	80.0	86.0	-6.0
Xanomeline Low Dose		Week 20	76.0	82.0	-6.0
Xanomeline Low Dose		Week 24	83.0	74.0	9.0
Xanomeline Low Dose		Week 24	86.0	86.0	0.0
Xanomeline Low Dose		Week 24	88.0	82.0	6.0
Xanomeline Low Dose		Week 26	82.0	74.0	8.0
Xanomeline Low Dose		Week 26	86.0	86.0	0.0
Xanomeline Low Dose		Week 26	87.0	82.0	5.0
Xanomeline Low Dose		Week 4	83.0	74.0	9.0
Xanomeline Low Dose		Week 4	95.0	86.0	9.0
Xanomeline Low Dose		Week 4	89.0	82.0	7.0
Xanomeline Low Dose		Week 6	76.0	74.0	2.0
Xanomeline Low Dose		Week 6	79.0	86.0	-7.0
Xanomeline Low Dose		Week 6	80.0	82.0	-2.0
Xanomeline Low Dose		Week 8	86.0	74.0	12.0
Xanomeline Low Dose		Week 8	96.0	86.0	10.0
Xanomeline Low Dose		Week 8	92.0	82.0	10.0
Xanomeline Low Dose			84.0	74.0
Xanomeline Low Dose			84.0	86.0
Xanomeline Low Dose			82.0	82.0
Xanomeline Low Dose			78.0	74.0
Xanomeline Low Dose			86.0	86.0
Xanomeline Low Dose			88.0	82.0
Placebo		Week 12	56.0	57.0	-1.0
Placebo		Week 12	74.0	69.0	5.0
Placebo		Week 12	64.0	64.0	0.0
Placebo		Week 16	61.0	57.0	4.0
Placebo		Week 16	62.0	69.0	-7.0
Placebo		Week 16	62.0	64.0	-2.0
Placebo		Week 2	50.0	57.0	-7.0
Placebo		Week 2	60.0	69.0	-9.0
Placebo		Week 2	55.0	64.0	-9.0
Placebo		Week 20	53.0	57.0	-4.0
Placebo		Week 20	60.0	69.0	-9.0
Placebo		Week 20	58.0	64.0	-6.0
Placebo		Week 24	50.0	57.0	-7.0
Placebo		Week 24	59.0	69.0	-10.0
Placebo		Week 24	56.0	64.0	-8.0
Placebo		Week 26	54.0	57.0	-3.0
Placebo		Week 26	55.0	69.0	-14.0
Placebo		Week 26	54.0	64.0	-10.0
Placebo		Week 4	57.0	57.0	0.0
Placebo		Week 4	62.0	69.0	-7.0
Placebo		Week 4	58.0	64.0	-6.0
Placebo		Week 6	53.0	57.0	-4.0
Placebo		Week 6	57.0	69.0	-12.0
Placebo		Week 6	56.0	64.0	-8.0
Placebo		Week 8	54.0	57.0	-3.0
Placebo		Week 8	68.0	69.0	-1.0
Placebo		Week 8	62.0	64.0	-2.0
Placebo			55.0	57.0
Placebo			65.0	69.0
Placebo			59.0	64.0
Xanomeline Low Dose		Week 2	74.0	57.0	17.0
Xanomeline Low Dose		Week 2	85.0	76.0	9.0
Xanomeline Low Dose		Week 2	84.0	64.0	20.0
Xanomeline Low Dose		Week 4	66.0	57.0	9.0
Xanomeline Low Dose		Week 4	79.0	76.0	3.0
Xanomeline Low Dose		Week 4	73.0	64.0	9.0
Xanomeline Low Dose		Week 6	63.0	57.0	6.0
Xanomeline Low Dose		Week 6	74.0	76.0	-2.0
Xanomeline Low Dose		Week 6	67.0	64.0	3.0
Xanomeline Low Dose		Week 8	65.0	57.0	8.0
Xanomeline Low Dose		Week 8	75.0	76.0	-1.0
Xanomeline Low Dose		Week 8	74.0	64.0	10.0
Xanomeline Low Dose			64.0	57.0
Xanomeline Low Dose			75.0	76.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			61.0	57.0
Xanomeline Low Dose			76.0	76.0
Xanomeline Low Dose			76.0	64.0
Placebo		Week 12	53.0	58.0	-5.0
Placebo		Week 12	62.0	56.0	6.0
Placebo		Week 12	62.0	57.0	5.0
Placebo		Week 16	51.0	58.0	-7.0
Placebo		Week 16	56.0	56.0	0.0
Placebo		Week 16	59.0	57.0	2.0
Placebo		Week 2	51.0	58.0	-7.0
Placebo		Week 2	54.0	56.0	-2.0
Placebo		Week 2	56.0	57.0	-1.0
Placebo		Week 20	60.0	58.0	2.0
Placebo		Week 20	54.0	56.0	-2.0
Placebo		Week 20	66.0	57.0	9.0
Placebo		Week 24	59.0	58.0	1.0
Placebo		Week 24	66.0	56.0	10.0
Placebo		Week 24	67.0	57.0	10.0
Placebo		Week 26	50.0	58.0	-8.0
Placebo		Week 26	59.0	56.0	3.0
Placebo		Week 26	57.0	57.0	0.0
Placebo		Week 4	52.0	58.0	-6.0
Placebo		Week 4	50.0	56.0	-6.0
Placebo		Week 4	54.0	57.0	-3.0
Placebo		Week 6	54.0	58.0	-4.0
Placebo		Week 6	60.0	56.0	4.0
Placebo		Week 6	59.0	57.0	2.0
Placebo		Week 8	52.0	58.0	-6.0
Placebo		Week 8	55.0	56.0	-1.0
Placebo		Week 8	56.0	57.0	-1.0
Placebo			50.0	58.0
Placebo			56.0	56.0
Placebo			54.0	57.0
Placebo			52.0	58.0
Placebo			52.0	56.0
Placebo			56.0	57.0
Xanomeline High Dose		Week 12	70.0	83.0	-13.0
Xanomeline High Dose		Week 12	84.0	87.0	-3.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 16	81.0	83.0	-2.0
Xanomeline High Dose		Week 16	87.0	87.0	0.0
Xanomeline High Dose		Week 16	83.0	80.0	3.0
Xanomeline High Dose		Week 2	87.0	83.0	4.0
Xanomeline High Dose		Week 2	86.0	87.0	-1.0
Xanomeline High Dose		Week 2	89.0	80.0	9.0
Xanomeline High Dose		Week 20	77.0	83.0	-6.0
Xanomeline High Dose		Week 20	89.0	87.0	2.0
Xanomeline High Dose		Week 20	80.0	80.0	0.0
Xanomeline High Dose		Week 24	69.0	83.0	-14.0
Xanomeline High Dose		Week 24	75.0	87.0	-12.0
Xanomeline High Dose		Week 24	70.0	80.0	-10.0
Xanomeline High Dose		Week 4	75.0	83.0	-8.0
Xanomeline High Dose		Week 4	77.0	87.0	-10.0
Xanomeline High Dose		Week 4	73.0	80.0	-7.0
Xanomeline High Dose		Week 6	81.0	83.0	-2.0
Xanomeline High Dose		Week 6	87.0	87.0	0.0
Xanomeline High Dose		Week 6	86.0	80.0	6.0
Xanomeline High Dose		Week 8	84.0	83.0	1.0
Xanomeline High Dose		Week 8	91.0	87.0	4.0
Xanomeline High Dose		Week 8	83.0	80.0	3.0
Xanomeline High Dose			82.0	83.0
Xanomeline High Dose			79.0	87.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			85.0	83.0
Xanomeline High Dose			86.0	87.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose		Week 12	80.0	64.0	16.0
Xanomeline High Dose		Week 12	85.0	70.0	15.0
Xanomeline High Dose		Week 12	89.0	70.0	19.0
Xanomeline High Dose		Week 2	70.0	64.0	6.0
Xanomeline High Dose		Week 2	72.0	70.0	2.0
Xanomeline High Dose		Week 2	71.0	70.0	1.0
Xanomeline High Dose		Week 4	83.0	64.0	19.0
Xanomeline High Dose		Week 4	88.0	70.0	18.0
Xanomeline High Dose		Week 4	87.0	70.0	17.0
Xanomeline High Dose		Week 6	79.0	64.0	15.0
Xanomeline High Dose		Week 6	86.0	70.0	16.0
Xanomeline High Dose		Week 6	88.0	70.0	18.0
Xanomeline High Dose		Week 8	84.0	64.0	20.0
Xanomeline High Dose		Week 8	85.0	70.0	15.0
Xanomeline High Dose		Week 8	87.0	70.0	17.0
Xanomeline High Dose			66.0	64.0
Xanomeline High Dose			69.0	70.0
Xanomeline High Dose			76.0	70.0
Xanomeline High Dose			82.0	64.0
Xanomeline High Dose			88.0	70.0
Xanomeline High Dose			86.0	70.0
Xanomeline High Dose		Week 12	83.0	84.0	-1.0
Xanomeline High Dose		Week 12	98.0	96.0	2.0
Xanomeline High Dose		Week 12	94.0	98.0	-4.0
Xanomeline High Dose		Week 16	86.0	84.0	2.0
Xanomeline High Dose		Week 16	89.0	96.0	-7.0
Xanomeline High Dose		Week 16	90.0	98.0	-8.0
Xanomeline High Dose		Week 2	84.0	84.0	0.0
Xanomeline High Dose		Week 2	82.0	96.0	-14.0
Xanomeline High Dose		Week 2	84.0	98.0	-14.0
Xanomeline High Dose		Week 20	87.0	84.0	3.0
Xanomeline High Dose		Week 20	95.0	96.0	-1.0
Xanomeline High Dose		Week 20	96.0	98.0	-2.0
Xanomeline High Dose		Week 24	77.0	84.0	-7.0
Xanomeline High Dose		Week 24	82.0	96.0	-14.0
Xanomeline High Dose		Week 24	81.0	98.0	-17.0
Xanomeline High Dose		Week 26	80.0	84.0	-4.0
Xanomeline High Dose		Week 26	89.0	96.0	-7.0
Xanomeline High Dose		Week 26	89.0	98.0	-9.0
Xanomeline High Dose		Week 4	85.0	84.0	1.0
Xanomeline High Dose		Week 4	90.0	96.0	-6.0
Xanomeline High Dose		Week 4	93.0	98.0	-5.0
Xanomeline High Dose		Week 6	80.0	84.0	-4.0
Xanomeline High Dose		Week 6	86.0	96.0	-10.0
Xanomeline High Dose		Week 6	86.0	98.0	-12.0
Xanomeline High Dose		Week 8	90.0	84.0	6.0
Xanomeline High Dose		Week 8	97.0	96.0	1.0
Xanomeline High Dose		Week 8	98.0	98.0	0.0
Xanomeline High Dose			86.0	84.0
Xanomeline High Dose			97.0	96.0
Xanomeline High Dose			98.0	98.0
Xanomeline Low Dose		Week 12	54.0	57.0	-3.0
Xanomeline Low Dose		Week 12	65.0	64.0	1.0
Xanomeline Low Dose		Week 12	62.0	70.0	-8.0
Xanomeline Low Dose		Week 2	56.0	57.0	-1.0
Xanomeline Low Dose		Week 2	67.0	64.0	3.0
Xanomeline Low Dose		Week 2	65.0	70.0	-5.0
Xanomeline Low Dose		Week 4	59.0	57.0	2.0
Xanomeline Low Dose		Week 4	81.0	64.0	17.0
Xanomeline Low Dose		Week 4	74.0	70.0	4.0
Xanomeline Low Dose		Week 6	55.0	57.0	-2.0
Xanomeline Low Dose		Week 6	60.0	64.0	-4.0
Xanomeline Low Dose		Week 6	58.0	70.0	-12.0
Xanomeline Low Dose		Week 8	54.0	57.0	-3.0
Xanomeline Low Dose		Week 8	63.0	64.0	-1.0
Xanomeline Low Dose		Week 8	64.0	70.0	-6.0
Xanomeline Low Dose			56.0	57.0
Xanomeline Low Dose			77.0	64.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			64.0	57.0
Xanomeline Low Dose			81.0	64.0
Xanomeline Low Dose			80.0	70.0
Xanomeline High Dose		Week 12	53.0	54.0	-1.0
Xanomeline High Dose		Week 12	55.0	62.0	-7.0
Xanomeline High Dose		Week 12	56.0	61.0	-5.0
Xanomeline High Dose		Week 2	72.0	54.0	18.0
Xanomeline High Dose		Week 2	80.0	62.0	18.0
Xanomeline High Dose		Week 2	82.0	61.0	21.0
Xanomeline High Dose		Week 4	52.0	54.0	-2.0
Xanomeline High Dose		Week 4	62.0	62.0	0.0
Xanomeline High Dose		Week 4	66.0	61.0	5.0
Xanomeline High Dose		Week 6	79.0	54.0	25.0
Xanomeline High Dose		Week 6	91.0	62.0	29.0
Xanomeline High Dose		Week 6	86.0	61.0	25.0
Xanomeline High Dose		Week 8	62.0	54.0	8.0
Xanomeline High Dose		Week 8	76.0	62.0	14.0
Xanomeline High Dose		Week 8	77.0	61.0	16.0
Xanomeline High Dose			72.0	54.0
Xanomeline High Dose			89.0	62.0
Xanomeline High Dose			87.0	61.0
Xanomeline High Dose			60.0	54.0
Xanomeline High Dose			64.0	62.0
Xanomeline High Dose			64.0	61.0
Xanomeline Low Dose		Week 12	60.0	63.0	-3.0
Xanomeline Low Dose		Week 12	71.0	73.0	-2.0
Xanomeline Low Dose		Week 12	69.0	69.0	0.0
Xanomeline Low Dose		Week 16	53.0	63.0	-10.0
Xanomeline Low Dose		Week 16	62.0	73.0	-11.0
Xanomeline Low Dose		Week 16	62.0	69.0	-7.0
Xanomeline Low Dose		Week 2	67.0	63.0	4.0
Xanomeline Low Dose		Week 2	78.0	73.0	5.0
Xanomeline Low Dose		Week 2	73.0	69.0	4.0
Xanomeline Low Dose		Week 20	61.0	63.0	-2.0
Xanomeline Low Dose		Week 20	79.0	73.0	6.0
Xanomeline Low Dose		Week 20	74.0	69.0	5.0
Xanomeline Low Dose		Week 24	56.0	63.0	-7.0
Xanomeline Low Dose		Week 24	65.0	73.0	-8.0
Xanomeline Low Dose		Week 24	65.0	69.0	-4.0
Xanomeline Low Dose		Week 26	56.0	63.0	-7.0
Xanomeline Low Dose		Week 26	69.0	73.0	-4.0
Xanomeline Low Dose		Week 26	68.0	69.0	-1.0
Xanomeline Low Dose		Week 4	60.0	63.0	-3.0
Xanomeline Low Dose		Week 4	72.0	73.0	-1.0
Xanomeline Low Dose		Week 4	66.0	69.0	-3.0
Xanomeline Low Dose		Week 6	65.0	63.0	2.0
Xanomeline Low Dose		Week 6	78.0	73.0	5.0
Xanomeline Low Dose		Week 6	75.0	69.0	6.0
Xanomeline Low Dose		Week 8	57.0	63.0	-6.0
Xanomeline Low Dose		Week 8	65.0	73.0	-8.0
Xanomeline Low Dose		Week 8	66.0	69.0	-3.0
Xanomeline Low Dose			63.0	63.0
Xanomeline Low Dose			75.0	73.0
Xanomeline Low Dose			72.0	69.0
Xanomeline Low Dose			65.0	63.0
Xanomeline Low Dose			77.0	73.0
Xanomeline Low Dose			73.0	69.0
Xanomeline Low Dose		Week 12	54.0	56.0	-2.0
Xanomeline Low Dose		Week 12	59.0	66.0	-7.0
Xanomeline Low Dose		Week 12	64.0	62.0	2.0
Xanomeline Low Dose		Week 16	57.0	56.0	1.0
Xanomeline Low Dose		Week 16	66.0	66.0	0.0
Xanomeline Low Dose		Week 16	61.0	62.0	-1.0
Xanomeline Low Dose		Week 2	54.0	56.0	-2.0
Xanomeline Low Dose		Week 2	70.0	66.0	4.0
Xanomeline Low Dose		Week 2	63.0	62.0	1.0
Xanomeline Low Dose		Week 20	54.0	56.0	-2.0
Xanomeline Low Dose		Week 20	71.0	66.0	5.0
Xanomeline Low Dose		Week 20	63.0	62.0	1.0
Xanomeline Low Dose		Week 24	53.0	56.0	-3.0
Xanomeline Low Dose		Week 24	59.0	66.0	-7.0
Xanomeline Low Dose		Week 24	56.0	62.0	-6.0
Xanomeline Low Dose		Week 26	54.0	56.0	-2.0
Xanomeline Low Dose		Week 26	72.0	66.0	6.0
Xanomeline Low Dose		Week 26	59.0	62.0	-3.0
Xanomeline Low Dose		Week 4	56.0	56.0	0.0
Xanomeline Low Dose		Week 4	66.0	66.0	0.0
Xanomeline Low Dose		Week 4	62.0	62.0	0.0
Xanomeline Low Dose		Week 6	54.0	56.0	-2.0
Xanomeline Low Dose		Week 6	66.0	66.0	0.0
Xanomeline Low Dose		Week 6	64.0	62.0	2.0
Xanomeline Low Dose		Week 8	53.0	56.0	-3.0
Xanomeline Low Dose		Week 8	67.0	66.0	1.0
Xanomeline Low Dose		Week 8	69.0	62.0	7.0
Xanomeline Low Dose			60.0	56.0
Xanomeline Low Dose			72.0	66.0
Xanomeline Low Dose			68.0	62.0
Xanomeline Low Dose			54.0	56.0
Xanomeline Low Dose			64.0	66.0
Xanomeline Low Dose			62.0	62.0
Xanomeline Low Dose		Week 2	62.0	80.0	-18.0
Xanomeline Low Dose		Week 2	82.0	94.0	-12.0
Xanomeline Low Dose		Week 2	83.0	86.0	-3.0
Xanomeline Low Dose			66.0	80.0
Xanomeline Low Dose			72.0	94.0
Xanomeline Low Dose			67.0	86.0
Placebo		Week 12	62.0	61.0	1.0
Placebo		Week 12	67.0	68.0	-1.0
Placebo		Week 12	65.0	67.0	-2.0
Placebo		Week 16	66.0	61.0	5.0
Placebo		Week 16	79.0	68.0	11.0
Placebo		Week 16	83.0	67.0	16.0
Placebo		Week 2	62.0	61.0	1.0
Placebo		Week 2	73.0	68.0	5.0
Placebo		Week 2	74.0	67.0	7.0
Placebo		Week 20	61.0	61.0	0.0
Placebo		Week 20	74.0	68.0	6.0
Placebo		Week 20	75.0	67.0	8.0
Placebo		Week 24	64.0	61.0	3.0
Placebo		Week 24	82.0	68.0	14.0
Placebo		Week 24	80.0	67.0	13.0
Placebo		Week 4	66.0	61.0	5.0
Placebo		Week 4	87.0	68.0	19.0
Placebo		Week 4	86.0	67.0	19.0
Placebo		Week 6	62.0	61.0	1.0
Placebo		Week 6	66.0	68.0	-2.0
Placebo		Week 6	68.0	67.0	1.0
Placebo		Week 8	59.0	61.0	-2.0
Placebo		Week 8	79.0	68.0	11.0
Placebo		Week 8	83.0	67.0	16.0
Placebo			62.0	61.0
Placebo			80.0	68.0
Placebo			70.0	67.0
Placebo			62.0	61.0
Placebo			70.0	68.0
Placebo			74.0	67.0
Placebo		Week 12	78.0	51.0	27.0
Placebo		Week 12	93.0	84.0	9.0
Placebo		Week 12	77.0	83.0	-6.0
Placebo		Week 16	59.0	51.0	8.0
Placebo		Week 16	62.0	84.0	-22.0
Placebo		Week 16	55.0	83.0	-28.0
Placebo		Week 2	59.0	51.0	8.0
Placebo		Week 2	75.0	84.0	-9.0
Placebo		Week 2	62.0	83.0	-21.0
Placebo		Week 20	70.0	51.0	19.0
Placebo		Week 20	85.0	84.0	1.0
Placebo		Week 20	79.0	83.0	-4.0
Placebo		Week 24	57.0	51.0	6.0
Placebo		Week 24	62.0	84.0	-22.0
Placebo		Week 24	56.0	83.0	-27.0
Placebo		Week 26	54.0	51.0	3.0
Placebo		Week 26	86.0	84.0	2.0
Placebo		Week 26	72.0	83.0	-11.0
Placebo		Week 4	79.0	51.0	28.0
Placebo		Week 4	96.0	84.0	12.0
Placebo		Week 4	90.0	83.0	7.0
Placebo		Week 6	59.0	51.0	8.0
Placebo		Week 6	65.0	84.0	-19.0
Placebo		Week 6	77.0	83.0	-6.0
Placebo		Week 8	57.0	51.0	6.0
Placebo		Week 8	82.0	84.0	-2.0
Placebo		Week 8	81.0	83.0	-2.0
Placebo			72.0	51.0
Placebo			74.0	84.0
Placebo			68.0	83.0
Placebo			57.0	51.0
Placebo			78.0	84.0
Placebo			72.0	83.0
Xanomeline High Dose		Week 12	63.0	77.0	-14.0
Xanomeline High Dose		Week 12	81.0	87.0	-6.0
Xanomeline High Dose		Week 12	76.0	89.0	-13.0
Xanomeline High Dose		Week 16	70.0	77.0	-7.0
Xanomeline High Dose		Week 16	82.0	87.0	-5.0
Xanomeline High Dose		Week 16	78.0	89.0	-11.0
Xanomeline High Dose		Week 2	84.0	77.0	7.0
Xanomeline High Dose		Week 2	88.0	87.0	1.0
Xanomeline High Dose		Week 2	88.0	89.0	-1.0
Xanomeline High Dose		Week 20	73.0	77.0	-4.0
Xanomeline High Dose		Week 20	86.0	87.0	-1.0
Xanomeline High Dose		Week 20	85.0	89.0	-4.0
Xanomeline High Dose		Week 24	92.0	77.0	15.0
Xanomeline High Dose		Week 24	98.0	87.0	11.0
Xanomeline High Dose		Week 24	96.0	89.0	7.0
Xanomeline High Dose		Week 26	79.0	77.0	2.0
Xanomeline High Dose		Week 26	86.0	87.0	-1.0
Xanomeline High Dose		Week 26	88.0	89.0	-1.0
Xanomeline High Dose		Week 4	70.0	77.0	-7.0
Xanomeline High Dose		Week 4	82.0	87.0	-5.0
Xanomeline High Dose		Week 4	78.0	89.0	-11.0
Xanomeline High Dose		Week 6	80.0	77.0	3.0
Xanomeline High Dose		Week 6	88.0	87.0	1.0
Xanomeline High Dose		Week 6	86.0	89.0	-3.0
Xanomeline High Dose		Week 8	70.0	77.0	-7.0
Xanomeline High Dose		Week 8	86.0	87.0	-1.0
Xanomeline High Dose		Week 8	81.0	89.0	-8.0
Xanomeline High Dose			80.0	77.0
Xanomeline High Dose			84.0	87.0
Xanomeline High Dose			86.0	89.0
Xanomeline High Dose			78.0	77.0
Xanomeline High Dose			82.0	87.0
Xanomeline High Dose			81.0	89.0
Placebo		Week 2	73.0	75.0	-2.0
Placebo		Week 2	86.0	79.0	7.0
Placebo		Week 2	83.0	80.0	3.0
Placebo		Week 12	77.0	57.0	20.0
Placebo		Week 12	88.0	60.0	28.0
Placebo		Week 12	86.0	59.0	27.0
Placebo		Week 16	53.0	57.0	-4.0
Placebo		Week 16	60.0	60.0	0.0
Placebo		Week 16	60.0	59.0	1.0
Placebo		Week 2	72.0	57.0	15.0
Placebo		Week 2	78.0	60.0	18.0
Placebo		Week 2	82.0	59.0	23.0
Placebo		Week 20	74.0	57.0	17.0
Placebo		Week 20	84.0	60.0	24.0
Placebo		Week 20	81.0	59.0	22.0
Placebo		Week 24	61.0	57.0	4.0
Placebo		Week 24	64.0	60.0	4.0
Placebo		Week 24	62.0	59.0	3.0
Placebo		Week 26	68.0	57.0	11.0
Placebo		Week 26	74.0	60.0	14.0
Placebo		Week 26	71.0	59.0	12.0
Placebo		Week 4	55.0	57.0	-2.0
Placebo		Week 4	58.0	60.0	-2.0
Placebo		Week 4	57.0	59.0	-2.0
Placebo		Week 6	74.0	57.0	17.0
Placebo		Week 6	84.0	60.0	24.0
Placebo		Week 6	80.0	59.0	21.0
Placebo		Week 8	62.0	57.0	5.0
Placebo		Week 8	66.0	60.0	6.0
Placebo		Week 8	64.0	59.0	5.0
Placebo			58.0	57.0
Placebo			64.0	60.0
Placebo			61.0	59.0
Placebo			58.0	57.0
Placebo			60.0	60.0
Placebo			61.0	59.0
Placebo		Week 12	61.0	62.0	-1.0
Placebo		Week 12	72.0	72.0	0.0
Placebo		Week 12	66.0	68.0	-2.0
Placebo		Week 16	62.0	62.0	0.0
Placebo		Week 16	66.0	72.0	-6.0
Placebo		Week 16	72.0	68.0	4.0
Placebo		Week 2	67.0	62.0	5.0
Placebo		Week 2	70.0	72.0	-2.0
Placebo		Week 2	69.0	68.0	1.0
Placebo		Week 20	67.0	62.0	5.0
Placebo		Week 20	70.0	72.0	-2.0
Placebo		Week 20	67.0	68.0	-1.0
Placebo		Week 24	60.0	62.0	-2.0
Placebo		Week 24	76.0	72.0	4.0
Placebo		Week 24	68.0	68.0	0.0
Placebo		Week 26	65.0	62.0	3.0
Placebo		Week 26	77.0	72.0	5.0
Placebo		Week 26	73.0	68.0	5.0
Placebo		Week 4	62.0	62.0	0.0
Placebo		Week 4	85.0	72.0	13.0
Placebo		Week 4	81.0	68.0	13.0
Placebo		Week 6	65.0	62.0	3.0
Placebo		Week 6	75.0	72.0	3.0
Placebo		Week 6	74.0	68.0	6.0
Placebo		Week 8	62.0	62.0	0.0
Placebo		Week 8	70.0	72.0	-2.0
Placebo		Week 8	64.0	68.0	-4.0
Placebo			65.0	62.0
Placebo			74.0	72.0
Placebo			73.0	68.0
Placebo			70.0	62.0
Placebo			77.0	72.0
Placebo			73.0	68.0
Xanomeline Low Dose		Week 2	74.0	68.0	6.0
Xanomeline Low Dose		Week 2	76.0	75.0	1.0
Xanomeline Low Dose		Week 2	76.0	72.0	4.0
Xanomeline Low Dose		Week 4	77.0	68.0	9.0
Xanomeline Low Dose		Week 4	85.0	75.0	10.0
Xanomeline Low Dose		Week 4	88.0	72.0	16.0
Xanomeline Low Dose		Week 6	73.0	68.0	5.0
Xanomeline Low Dose		Week 6	80.0	75.0	5.0
Xanomeline Low Dose		Week 6	76.0	72.0	4.0
Placebo		Week 12	51.0	52.0	-1.0
Placebo		Week 12	59.0	56.0	3.0
Placebo		Week 12	57.0	54.0	3.0
Placebo		Week 16	50.0	52.0	-2.0
Placebo		Week 16	54.0	56.0	-2.0
Placebo		Week 16	57.0	54.0	3.0
Placebo		Week 2	53.0	52.0	1.0
Placebo		Week 2	53.0	56.0	-3.0
Placebo		Week 2	54.0	54.0	0.0
Placebo		Week 20	56.0	52.0	4.0
Placebo		Week 20	71.0	56.0	15.0
Placebo		Week 20	65.0	54.0	11.0
Placebo		Week 24	52.0	52.0	0.0
Placebo		Week 24	55.0	56.0	-1.0
Placebo		Week 24	57.0	54.0	3.0
Placebo		Week 26	55.0	52.0	3.0
Placebo		Week 26	66.0	56.0	10.0
Placebo		Week 26	60.0	54.0	6.0
Placebo		Week 4	54.0	52.0	2.0
Placebo		Week 4	60.0	56.0	4.0
Placebo		Week 4	57.0	54.0	3.0
Placebo		Week 6	53.0	52.0	1.0
Placebo		Week 6	59.0	56.0	3.0
Placebo		Week 6	55.0	54.0	1.0
Placebo		Week 8	52.0	52.0	0.0
Placebo		Week 8	54.0	56.0	-2.0
Placebo		Week 8	58.0	54.0	4.0
Placebo			50.0	52.0
Placebo			50.0	56.0
Placebo			51.0	54.0
Placebo			50.0	52.0
Placebo			59.0	56.0
Placebo			51.0	54.0
Xanomeline Low Dose		Week 12	70.0	78.0	-8.0
Xanomeline Low Dose		Week 12	74.0	78.0	-4.0
Xanomeline Low Dose		Week 12	74.0	81.0	-7.0
Xanomeline Low Dose		Week 16	68.0	78.0	-10.0
Xanomeline Low Dose		Week 16	73.0	78.0	-5.0
Xanomeline Low Dose		Week 16	73.0	81.0	-8.0
Xanomeline Low Dose		Week 2	78.0	78.0	0.0
Xanomeline Low Dose		Week 2	83.0	78.0	5.0
Xanomeline Low Dose		Week 2	87.0	81.0	6.0
Xanomeline Low Dose		Week 20	96.0	78.0	18.0
Xanomeline Low Dose		Week 20	98.0	78.0	20.0
Xanomeline Low Dose		Week 20	97.0	81.0	16.0
Xanomeline Low Dose		Week 24	77.0	78.0	-1.0
Xanomeline Low Dose		Week 24	80.0	78.0	2.0
Xanomeline Low Dose		Week 24	83.0	81.0	2.0
Xanomeline Low Dose		Week 26	68.0	78.0	-10.0
Xanomeline Low Dose		Week 26	74.0	78.0	-4.0
Xanomeline Low Dose		Week 26	72.0	81.0	-9.0
Xanomeline Low Dose		Week 4	73.0	78.0	-5.0
Xanomeline Low Dose		Week 4	78.0	78.0	0.0
Xanomeline Low Dose		Week 4	79.0	81.0	-2.0
Xanomeline Low Dose		Week 6	76.0	78.0	-2.0
Xanomeline Low Dose		Week 6	80.0	78.0	2.0
Xanomeline Low Dose		Week 6	81.0	81.0	0.0
Xanomeline Low Dose		Week 8	67.0	78.0	-11.0
Xanomeline Low Dose		Week 8	69.0	78.0	-9.0
Xanomeline Low Dose		Week 8	71.0	81.0	-10.0
Xanomeline Low Dose			76.0	78.0
Xanomeline Low Dose			72.0	78.0
Xanomeline Low Dose			79.0	81.0
Xanomeline Low Dose			76.0	78.0
Xanomeline Low Dose			78.0	78.0
Xanomeline Low Dose			72.0	81.0
Xanomeline High Dose		Week 2	65.0	64.0	1.0
Xanomeline High Dose		Week 2	64.0	72.0	-8.0
Xanomeline High Dose		Week 2	64.0	68.0	-4.0
Xanomeline High Dose		Week 4	62.0	64.0	-2.0
Xanomeline High Dose		Week 4	65.0	72.0	-7.0
Xanomeline High Dose		Week 4	62.0	68.0	-6.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			77.0	72.0
Xanomeline High Dose			77.0	68.0
Xanomeline High Dose			69.0	64.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			74.0	68.0
Xanomeline Low Dose		Week 2	78.0	76.0	2.0
Xanomeline Low Dose		Week 2	84.0	78.0	6.0
Xanomeline Low Dose		Week 2	82.0	80.0	2.0
Xanomeline Low Dose		Week 4	80.0	76.0	4.0
Xanomeline Low Dose		Week 4	77.0	78.0	-1.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	78.0	76.0	2.0
Xanomeline Low Dose		Week 6	76.0	78.0	-2.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 8	80.0	76.0	4.0
Xanomeline Low Dose		Week 8	80.0	78.0	2.0
Xanomeline Low Dose		Week 8	82.0	80.0	2.0
Xanomeline Low Dose			78.0	76.0
Xanomeline Low Dose			82.0	78.0
Xanomeline Low Dose			76.0	80.0
Xanomeline Low Dose			50.0	76.0
Xanomeline Low Dose			56.0	78.0
Xanomeline Low Dose			56.0	80.0
Placebo		Week 12	84.0	60.0	24.0
Placebo		Week 12	82.0	80.0	2.0
Placebo		Week 12	82.0	82.0	0.0
Placebo		Week 16	88.0	60.0	28.0
Placebo		Week 16	86.0	80.0	6.0
Placebo		Week 16	88.0	82.0	6.0
Placebo		Week 2	88.0	60.0	28.0
Placebo		Week 2	92.0	80.0	12.0
Placebo		Week 2	88.0	82.0	6.0
Placebo		Week 20	86.0	60.0	26.0
Placebo		Week 20	88.0	80.0	8.0
Placebo		Week 20	86.0	82.0	4.0
Placebo		Week 24	84.0	60.0	24.0
Placebo		Week 24	84.0	80.0	4.0
Placebo		Week 24	82.0	82.0	0.0
Placebo		Week 26	88.0	60.0	28.0
Placebo		Week 26	86.0	80.0	6.0
Placebo		Week 26	88.0	82.0	6.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	80.0	82.0	-2.0
Placebo		Week 6	80.0	60.0	20.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 6	88.0	82.0	6.0
Placebo		Week 8	90.0	60.0	30.0
Placebo		Week 8	94.0	80.0	14.0
Placebo		Week 8	94.0	82.0	12.0
Placebo			84.0	60.0
Placebo			86.0	80.0
Placebo			88.0	82.0
Placebo			92.0	60.0
Placebo			92.0	80.0
Placebo			88.0	82.0
Xanomeline High Dose		Week 12	74.0	76.0	-2.0
Xanomeline High Dose		Week 12	78.0	84.0	-6.0
Xanomeline High Dose		Week 12	76.0	88.0	-12.0
Xanomeline High Dose		Week 2	84.0	76.0	8.0
Xanomeline High Dose		Week 2	86.0	84.0	2.0
Xanomeline High Dose		Week 2	82.0	88.0	-6.0
Xanomeline High Dose		Week 4	75.0	76.0	-1.0
Xanomeline High Dose		Week 4	73.0	84.0	-11.0
Xanomeline High Dose		Week 4	77.0	88.0	-11.0
Xanomeline High Dose		Week 6	68.0	76.0	-8.0
Xanomeline High Dose		Week 6	72.0	84.0	-12.0
Xanomeline High Dose		Week 6	72.0	88.0	-16.0
Xanomeline High Dose		Week 8	74.0	76.0	-2.0
Xanomeline High Dose		Week 8	66.0	84.0	-18.0
Xanomeline High Dose		Week 8	70.0	88.0	-18.0
Xanomeline High Dose			84.0	76.0
Xanomeline High Dose			86.0	84.0
Xanomeline High Dose			82.0	88.0
Xanomeline High Dose			76.0	76.0
Xanomeline High Dose			80.0	84.0
Xanomeline High Dose			84.0	88.0
Xanomeline Low Dose		Week 12	72.0	80.0	-8.0
Xanomeline Low Dose		Week 12	72.0	78.0	-6.0
Xanomeline Low Dose		Week 12	74.0	80.0	-6.0
Xanomeline Low Dose		Week 2	72.0	80.0	-8.0
Xanomeline Low Dose		Week 2	80.0	78.0	2.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	72.0	80.0	-8.0
Xanomeline Low Dose		Week 4	72.0	78.0	-6.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	62.0	80.0	-18.0
Xanomeline Low Dose		Week 6	64.0	78.0	-14.0
Xanomeline Low Dose		Week 6	62.0	80.0	-18.0
Xanomeline Low Dose		Week 8	78.0	80.0	-2.0
Xanomeline Low Dose		Week 8	79.0	78.0	1.0
Xanomeline Low Dose		Week 8	80.0	80.0	0.0
Xanomeline Low Dose			66.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			68.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			74.0	80.0
Placebo		Week 2	66.0	74.0	-8.0
Placebo		Week 2	74.0	82.0	-8.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 4	78.0	74.0	4.0
Placebo		Week 4	78.0	82.0	-4.0
Placebo		Week 4	76.0	80.0	-4.0
Placebo			78.0	74.0
Placebo			78.0	82.0
Placebo			78.0	80.0
Placebo			68.0	74.0
Placebo			70.0	82.0
Placebo			74.0	80.0
Placebo		Week 12	78.0	72.0	6.0
Placebo		Week 12	80.0	78.0	2.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 16	74.0	72.0	2.0
Placebo		Week 16	78.0	78.0	0.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 2	70.0	72.0	-2.0
Placebo		Week 2	78.0	78.0	0.0
Placebo		Week 2	79.0	80.0	-1.0
Placebo		Week 20	67.0	72.0	-5.0
Placebo		Week 20	66.0	78.0	-12.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 24	81.0	72.0	9.0
Placebo		Week 24	80.0	78.0	2.0
Placebo		Week 24	76.0	80.0	-4.0
Placebo		Week 26	73.0	72.0	1.0
Placebo		Week 26	72.0	78.0	-6.0
Placebo		Week 26	74.0	80.0	-6.0
Placebo		Week 4	78.0	72.0	6.0
Placebo		Week 4	79.0	78.0	1.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 6	74.0	72.0	2.0
Placebo		Week 6	70.0	78.0	-8.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 8	78.0	72.0	6.0
Placebo		Week 8	80.0	78.0	2.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			70.0	72.0
Placebo			72.0	78.0
Placebo			80.0	80.0
Placebo			78.0	72.0
Placebo			79.0	78.0
Placebo			78.0	80.0
Xanomeline Low Dose		Week 12	80.0	64.0	16.0
Xanomeline Low Dose		Week 12	84.0	62.0	22.0
Xanomeline Low Dose		Week 12	88.0	60.0	28.0
Xanomeline Low Dose		Week 16	80.0	64.0	16.0
Xanomeline Low Dose		Week 16	84.0	62.0	22.0
Xanomeline Low Dose		Week 16	84.0	60.0	24.0
Xanomeline Low Dose		Week 2	72.0	64.0	8.0
Xanomeline Low Dose		Week 2	80.0	62.0	18.0
Xanomeline Low Dose		Week 2	80.0	60.0	20.0
Xanomeline Low Dose		Week 4	68.0	64.0	4.0
Xanomeline Low Dose		Week 4	76.0	62.0	14.0
Xanomeline Low Dose		Week 4	80.0	60.0	20.0
Xanomeline Low Dose		Week 6	68.0	64.0	4.0
Xanomeline Low Dose		Week 6	72.0	62.0	10.0
Xanomeline Low Dose		Week 6	84.0	60.0	24.0
Xanomeline Low Dose		Week 8	82.0	64.0	18.0
Xanomeline Low Dose		Week 8	80.0	62.0	18.0
Xanomeline Low Dose		Week 8	76.0	60.0	16.0
Xanomeline Low Dose			80.0	64.0
Xanomeline Low Dose			82.0	62.0
Xanomeline Low Dose			82.0	60.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			68.0	62.0
Xanomeline Low Dose			70.0	60.0
Xanomeline Low Dose		Week 2	84.0	72.0	12.0
Xanomeline Low Dose		Week 2	88.0	80.0	8.0
Xanomeline Low Dose		Week 2	86.0	72.0	14.0
Xanomeline Low Dose		Week 4	85.0	72.0	13.0
Xanomeline Low Dose		Week 4	88.0	80.0	8.0
Xanomeline Low Dose		Week 4	84.0	72.0	12.0
Xanomeline Low Dose		Week 6	84.0	72.0	12.0
Xanomeline Low Dose		Week 6	88.0	80.0	8.0
Xanomeline Low Dose		Week 6	84.0	72.0	12.0
Xanomeline Low Dose			84.0	72.0
Xanomeline Low Dose			86.0	80.0
Xanomeline Low Dose			82.0	72.0
Placebo		Week 12	68.0	80.0	-12.0
Placebo		Week 12	66.0	76.0	-10.0
Placebo		Week 12	66.0	72.0	-6.0
Placebo		Week 16	60.0	80.0	-20.0
Placebo		Week 16	62.0	76.0	-14.0
Placebo		Week 16	62.0	72.0	-10.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	78.0	76.0	2.0
Placebo		Week 2	76.0	72.0	4.0
Placebo		Week 20	68.0	80.0	-12.0
Placebo		Week 20	68.0	76.0	-8.0
Placebo		Week 20	68.0	72.0	-4.0
Placebo		Week 24	64.0	80.0	-16.0
Placebo		Week 24	64.0	76.0	-12.0
Placebo		Week 24	68.0	72.0	-4.0
Placebo		Week 26	56.0	80.0	-24.0
Placebo		Week 26	56.0	76.0	-20.0
Placebo		Week 26	60.0	72.0	-12.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	76.0	72.0	4.0
Placebo		Week 6	64.0	80.0	-16.0
Placebo		Week 6	68.0	76.0	-8.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 8	60.0	80.0	-20.0
Placebo		Week 8	68.0	76.0	-8.0
Placebo		Week 8	76.0	72.0	4.0
Placebo			78.0	80.0
Placebo			80.0	76.0
Placebo			80.0	72.0
Placebo			82.0	80.0
Placebo			84.0	76.0
Placebo			84.0	72.0
Xanomeline High Dose		Week 12	74.0	82.0	-8.0
Xanomeline High Dose		Week 12	78.0	84.0	-6.0
Xanomeline High Dose		Week 12	80.0	86.0	-6.0
Xanomeline High Dose		Week 16	60.0	82.0	-22.0
Xanomeline High Dose		Week 16	60.0	84.0	-24.0
Xanomeline High Dose		Week 16	66.0	86.0	-20.0
Xanomeline High Dose		Week 2	78.0	82.0	-4.0
Xanomeline High Dose		Week 2	76.0	84.0	-8.0
Xanomeline High Dose		Week 2	80.0	86.0	-6.0
Xanomeline High Dose		Week 20	86.0	82.0	4.0
Xanomeline High Dose		Week 20	88.0	84.0	4.0
Xanomeline High Dose		Week 20	90.0	86.0	4.0
Xanomeline High Dose		Week 24	80.0	82.0	-2.0
Xanomeline High Dose		Week 24	80.0	84.0	-4.0
Xanomeline High Dose		Week 24	80.0	86.0	-6.0
Xanomeline High Dose		Week 4	74.0	82.0	-8.0
Xanomeline High Dose		Week 4	76.0	84.0	-8.0
Xanomeline High Dose		Week 4	78.0	86.0	-8.0
Xanomeline High Dose		Week 6	72.0	82.0	-10.0
Xanomeline High Dose		Week 6	70.0	84.0	-14.0
Xanomeline High Dose		Week 6	72.0	86.0	-14.0
Xanomeline High Dose		Week 8	72.0	82.0	-10.0
Xanomeline High Dose		Week 8	76.0	84.0	-8.0
Xanomeline High Dose		Week 8	72.0	86.0	-14.0
Xanomeline High Dose			76.0	82.0
Xanomeline High Dose			78.0	84.0
Xanomeline High Dose			78.0	86.0
Xanomeline High Dose			74.0	82.0
Xanomeline High Dose			72.0	84.0
Xanomeline High Dose			76.0	86.0
Xanomeline High Dose		Week 12	80.0	64.0	16.0
Xanomeline High Dose		Week 12	80.0	66.0	14.0
Xanomeline High Dose		Week 12	84.0	64.0	20.0
Xanomeline High Dose		Week 16	84.0	64.0	20.0
Xanomeline High Dose		Week 16	88.0	66.0	22.0
Xanomeline High Dose		Week 16	96.0	64.0	32.0
Xanomeline High Dose		Week 2	88.0	64.0	24.0
Xanomeline High Dose		Week 2	68.0	66.0	2.0
Xanomeline High Dose		Week 2	80.0	64.0	16.0
Xanomeline High Dose		Week 4	88.0	64.0	24.0
Xanomeline High Dose		Week 4	80.0	66.0	14.0
Xanomeline High Dose		Week 4	90.0	64.0	26.0
Xanomeline High Dose		Week 6	80.0	64.0	16.0
Xanomeline High Dose		Week 6	84.0	66.0	18.0
Xanomeline High Dose		Week 6	84.0	64.0	20.0
Xanomeline High Dose		Week 8	80.0	64.0	16.0
Xanomeline High Dose		Week 8	80.0	66.0	14.0
Xanomeline High Dose		Week 8	82.0	64.0	18.0
Xanomeline High Dose			94.0	64.0
Xanomeline High Dose			88.0	66.0
Xanomeline High Dose			92.0	64.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose			84.0	66.0
Xanomeline High Dose			82.0	64.0
Placebo		Week 12	88.0	64.0	24.0
Placebo		Week 12	100.0	64.0	36.0
Placebo		Week 12	104.0	68.0	36.0
Placebo		Week 16	86.0	64.0	22.0
Placebo		Week 16	84.0	64.0	20.0
Placebo		Week 16	82.0	68.0	14.0
Placebo		Week 2	100.0	64.0	36.0
Placebo		Week 2	106.0	64.0	42.0
Placebo		Week 2	104.0	68.0	36.0
Placebo		Week 20	84.0	64.0	20.0
Placebo		Week 20	88.0	64.0	24.0
Placebo		Week 20	92.0	68.0	24.0
Placebo		Week 24	84.0	64.0	20.0
Placebo		Week 24	82.0	64.0	18.0
Placebo		Week 24	82.0	68.0	14.0
Placebo		Week 26	104.0	64.0	40.0
Placebo		Week 26	108.0	64.0	44.0
Placebo		Week 26	100.0	68.0	32.0
Placebo		Week 4	74.0	64.0	10.0
Placebo		Week 4	80.0	64.0	16.0
Placebo		Week 4	86.0	68.0	18.0
Placebo		Week 6	84.0	64.0	20.0
Placebo		Week 6	68.0	64.0	4.0
Placebo		Week 6	80.0	68.0	12.0
Placebo		Week 8	72.0	64.0	8.0
Placebo		Week 8	80.0	64.0	16.0
Placebo		Week 8	82.0	68.0	14.0
Placebo			84.0	64.0
Placebo			89.0	64.0
Placebo			88.0	68.0
Placebo			86.0	64.0
Placebo			90.0	64.0
Placebo			92.0	68.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 4	80.0	68.0	12.0
Xanomeline High Dose		Week 4	90.0	72.0	18.0
Xanomeline High Dose		Week 4	90.0	68.0	22.0
Xanomeline High Dose			88.0	68.0
Xanomeline High Dose			96.0	72.0
Xanomeline High Dose			92.0	68.0
Xanomeline High Dose			92.0	68.0
Xanomeline High Dose			100.0	72.0
Xanomeline High Dose			100.0	68.0
Xanomeline Low Dose		Week 12	64.0	64.0	0.0
Xanomeline Low Dose		Week 12	76.0	80.0	-4.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 16	60.0	64.0	-4.0
Xanomeline Low Dose		Week 16	68.0	80.0	-12.0
Xanomeline Low Dose		Week 16	64.0	68.0	-4.0
Xanomeline Low Dose		Week 2	72.0	64.0	8.0
Xanomeline Low Dose		Week 2	70.0	80.0	-10.0
Xanomeline Low Dose		Week 2	72.0	68.0	4.0
Xanomeline Low Dose		Week 20	50.0	64.0	-14.0
Xanomeline Low Dose		Week 20	40.0	80.0	-40.0
Xanomeline Low Dose		Week 20	50.0	68.0	-18.0
Xanomeline Low Dose		Week 24	56.0	64.0	-8.0
Xanomeline Low Dose		Week 24	60.0	80.0	-20.0
Xanomeline Low Dose		Week 24	56.0	68.0	-12.0
Xanomeline Low Dose		Week 26	64.0	64.0	0.0
Xanomeline Low Dose		Week 26	60.0	80.0	-20.0
Xanomeline Low Dose		Week 26	64.0	68.0	-4.0
Xanomeline Low Dose		Week 4	64.0	64.0	0.0
Xanomeline Low Dose		Week 4	76.0	80.0	-4.0
Xanomeline Low Dose		Week 4	72.0	68.0	4.0
Xanomeline Low Dose		Week 6	68.0	64.0	4.0
Xanomeline Low Dose		Week 6	72.0	80.0	-8.0
Xanomeline Low Dose		Week 6	76.0	68.0	8.0
Xanomeline Low Dose		Week 8	68.0	64.0	4.0
Xanomeline Low Dose		Week 8	76.0	80.0	-4.0
Xanomeline Low Dose		Week 8	78.0	68.0	10.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			74.0	68.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			66.0	68.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	80.0	84.0	-4.0
Xanomeline High Dose		Week 12	80.0	82.0	-2.0
Xanomeline High Dose		Week 16	85.0	78.0	7.0
Xanomeline High Dose		Week 16	86.0	84.0	2.0
Xanomeline High Dose		Week 16	86.0	82.0	4.0
Xanomeline High Dose		Week 2	86.0	78.0	8.0
Xanomeline High Dose		Week 2	88.0	84.0	4.0
Xanomeline High Dose		Week 2	88.0	82.0	6.0
Xanomeline High Dose		Week 20	85.0	78.0	7.0
Xanomeline High Dose		Week 20	87.0	84.0	3.0
Xanomeline High Dose		Week 20	80.0	82.0	-2.0
Xanomeline High Dose		Week 24	76.0	78.0	-2.0
Xanomeline High Dose		Week 24	80.0	84.0	-4.0
Xanomeline High Dose		Week 24	80.0	82.0	-2.0
Xanomeline High Dose		Week 26	85.0	78.0	7.0
Xanomeline High Dose		Week 26	88.0	84.0	4.0
Xanomeline High Dose		Week 26	88.0	82.0	6.0
Xanomeline High Dose		Week 4	88.0	78.0	10.0
Xanomeline High Dose		Week 4	89.0	84.0	5.0
Xanomeline High Dose		Week 4	88.0	82.0	6.0
Xanomeline High Dose		Week 6	82.0	78.0	4.0
Xanomeline High Dose		Week 6	86.0	84.0	2.0
Xanomeline High Dose		Week 6	89.0	82.0	7.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose		Week 8	79.0	84.0	-5.0
Xanomeline High Dose		Week 8	77.0	82.0	-5.0
Xanomeline High Dose			81.0	78.0
Xanomeline High Dose			81.0	84.0
Xanomeline High Dose			84.0	82.0
Xanomeline High Dose			87.0	78.0
Xanomeline High Dose			88.0	84.0
Xanomeline High Dose			84.0	82.0
Xanomeline High Dose		Week 2	64.0	58.0	6.0
Xanomeline High Dose		Week 4	68.0	58.0	10.0
Xanomeline High Dose		Week 4	72.0	66.0	6.0
Xanomeline High Dose		Week 4	72.0	60.0	12.0
Xanomeline High Dose			72.0	58.0
Xanomeline High Dose			66.0	66.0
Xanomeline High Dose			66.0	60.0
Xanomeline High Dose			70.0	58.0
Xanomeline High Dose			76.0	66.0
Xanomeline High Dose			72.0	60.0
Xanomeline Low Dose		Week 2	68.0	72.0	-4.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	70.0	68.0	2.0
Xanomeline Low Dose			74.0	72.0
Xanomeline Low Dose			64.0	72.0
Xanomeline Low Dose			68.0	68.0
Placebo		Week 12	68.0	74.0	-6.0
Placebo		Week 12	72.0	78.0	-6.0
Placebo		Week 12	72.0	74.0	-2.0
Placebo		Week 16	68.0	74.0	-6.0
Placebo		Week 16	74.0	78.0	-4.0
Placebo		Week 16	72.0	74.0	-2.0
Placebo		Week 2	64.0	74.0	-10.0
Placebo		Week 2	68.0	78.0	-10.0
Placebo		Week 2	68.0	74.0	-6.0
Placebo		Week 4	68.0	74.0	-6.0
Placebo		Week 4	68.0	78.0	-10.0
Placebo		Week 4	64.0	74.0	-10.0
Placebo		Week 6	68.0	74.0	-6.0
Placebo		Week 6	72.0	78.0	-6.0
Placebo		Week 6	70.0	74.0	-4.0
Placebo		Week 8	72.0	74.0	-2.0
Placebo		Week 8	72.0	78.0	-6.0
Placebo		Week 8	72.0	74.0	-2.0
Placebo			64.0	74.0
Placebo			72.0	78.0
Placebo			72.0	74.0
Placebo			64.0	74.0
Placebo			68.0	78.0
Placebo			68.0	74.0
Xanomeline High Dose		Week 2	68.0	76.0	-8.0
Xanomeline High Dose		Week 2	68.0	72.0	-4.0
Xanomeline High Dose		Week 2	68.0	80.0	-12.0
Xanomeline High Dose		Week 4	72.0	76.0	-4.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 4	76.0	80.0	-4.0
Xanomeline High Dose			72.0	76.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			80.0	80.0
Xanomeline Low Dose		Week 2	90.0	68.0	22.0
Xanomeline Low Dose		Week 2	88.0	66.0	22.0
Xanomeline Low Dose		Week 2	86.0	74.0	12.0
Xanomeline Low Dose			80.0	68.0
Xanomeline Low Dose			82.0	66.0
Xanomeline Low Dose			88.0	74.0
Xanomeline High Dose		Week 2	58.0	64.0	-6.0
Xanomeline High Dose		Week 2	60.0	68.0	-8.0
Xanomeline High Dose		Week 2	64.0	64.0	0.0
Xanomeline High Dose		Week 4	66.0	64.0	2.0
Xanomeline High Dose		Week 4	63.0	68.0	-5.0
Xanomeline High Dose		Week 4	60.0	64.0	-4.0
Xanomeline High Dose		Week 6	64.0	64.0	0.0
Xanomeline High Dose		Week 6	68.0	68.0	0.0
Xanomeline High Dose		Week 6	68.0	64.0	4.0
Xanomeline High Dose		Week 8	68.0	64.0	4.0
Xanomeline High Dose		Week 8	72.0	68.0	4.0
Xanomeline High Dose		Week 8	70.0	64.0	6.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			62.0	64.0
Xanomeline High Dose			66.0	68.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose		Week 2	60.0	68.0	-8.0
Xanomeline High Dose		Week 2	69.0	80.0	-11.0
Xanomeline High Dose		Week 2	75.0	68.0	7.0
Xanomeline High Dose		Week 4	68.0	68.0	0.0
Xanomeline High Dose		Week 4	72.0	80.0	-8.0
Xanomeline High Dose		Week 4	70.0	68.0	2.0
Xanomeline High Dose		Week 6	64.0	68.0	-4.0
Xanomeline High Dose		Week 6	72.0	80.0	-8.0
Xanomeline High Dose		Week 6	70.0	68.0	2.0
Xanomeline High Dose			66.0	68.0
Xanomeline High Dose			75.0	80.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			66.0	68.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose		Week 12	72.0	64.0	8.0
Xanomeline High Dose		Week 12	80.0	72.0	8.0
Xanomeline High Dose		Week 12	80.0	68.0	12.0
Xanomeline High Dose		Week 2	72.0	64.0	8.0
Xanomeline High Dose		Week 2	80.0	72.0	8.0
Xanomeline High Dose		Week 2	76.0	68.0	8.0
Xanomeline High Dose		Week 4	76.0	64.0	12.0
Xanomeline High Dose		Week 4	80.0	72.0	8.0
Xanomeline High Dose		Week 4	80.0	68.0	12.0
Xanomeline High Dose		Week 6	80.0	64.0	16.0
Xanomeline High Dose		Week 6	88.0	72.0	16.0
Xanomeline High Dose		Week 6	88.0	68.0	20.0
Xanomeline High Dose		Week 8	76.0	64.0	12.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 8	80.0	68.0	12.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			80.0	68.0
Xanomeline Low Dose		Week 12	64.0	56.0	8.0
Xanomeline Low Dose		Week 12	72.0	60.0	12.0
Xanomeline Low Dose		Week 12	68.0	56.0	12.0
Xanomeline Low Dose		Week 16	68.0	56.0	12.0
Xanomeline Low Dose		Week 16	74.0	60.0	14.0
Xanomeline Low Dose		Week 16	72.0	56.0	16.0
Xanomeline Low Dose		Week 2	72.0	56.0	16.0
Xanomeline Low Dose		Week 2	88.0	60.0	28.0
Xanomeline Low Dose		Week 2	92.0	56.0	36.0
Xanomeline Low Dose		Week 20	64.0	56.0	8.0
Xanomeline Low Dose		Week 20	70.0	60.0	10.0
Xanomeline Low Dose		Week 20	68.0	56.0	12.0
Xanomeline Low Dose		Week 4	64.0	56.0	8.0
Xanomeline Low Dose		Week 4	76.0	60.0	16.0
Xanomeline Low Dose		Week 4	80.0	56.0	24.0
Xanomeline Low Dose		Week 6	60.0	56.0	4.0
Xanomeline Low Dose		Week 6	64.0	60.0	4.0
Xanomeline Low Dose		Week 6	60.0	56.0	4.0
Xanomeline Low Dose		Week 8	62.0	56.0	6.0
Xanomeline Low Dose		Week 8	74.0	60.0	14.0
Xanomeline Low Dose		Week 8	70.0	56.0	14.0
Xanomeline Low Dose			60.0	56.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			56.0	56.0
Xanomeline Low Dose			60.0	56.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			68.0	56.0
Xanomeline Low Dose		Week 2	64.0	60.0	4.0
Xanomeline Low Dose		Week 2	78.0	72.0	6.0
Xanomeline Low Dose		Week 2	80.0	66.0	14.0
Xanomeline Low Dose		Week 4	63.0	60.0	3.0
Xanomeline Low Dose		Week 4	78.0	72.0	6.0
Xanomeline Low Dose		Week 4	82.0	66.0	16.0
Xanomeline Low Dose		Week 6	68.0	60.0	8.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 6	72.0	66.0	6.0
Xanomeline Low Dose		Week 8	66.0	60.0	6.0
Xanomeline Low Dose		Week 8	80.0	72.0	8.0
Xanomeline Low Dose		Week 8	84.0	66.0	18.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			70.0	72.0
Xanomeline Low Dose			62.0	66.0
Xanomeline Low Dose			72.0	60.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose			76.0	66.0
Placebo		Week 12	68.0	60.0	8.0
Placebo		Week 12	72.0	72.0	0.0
Placebo		Week 12	74.0	64.0	10.0
Placebo		Week 16	66.0	60.0	6.0
Placebo		Week 16	70.0	72.0	-2.0
Placebo		Week 16	70.0	64.0	6.0
Placebo		Week 2	60.0	60.0	0.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 2	72.0	64.0	8.0
Placebo		Week 20	68.0	60.0	8.0
Placebo		Week 20	72.0	72.0	0.0
Placebo		Week 20	72.0	64.0	8.0
Placebo		Week 24	64.0	60.0	4.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 24	72.0	64.0	8.0
Placebo		Week 26	70.0	60.0	10.0
Placebo		Week 26	74.0	72.0	2.0
Placebo		Week 26	72.0	64.0	8.0
Placebo		Week 4	64.0	60.0	4.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	68.0	64.0	4.0
Placebo		Week 6	64.0	60.0	4.0
Placebo		Week 6	70.0	72.0	-2.0
Placebo		Week 6	68.0	64.0	4.0
Placebo		Week 8	68.0	60.0	8.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	72.0	64.0	8.0
Placebo			64.0	60.0
Placebo			68.0	72.0
Placebo			64.0	64.0
Placebo			68.0	60.0
Placebo			68.0	72.0
Placebo			64.0	64.0
Xanomeline Low Dose		Week 12	74.0	68.0	6.0
Xanomeline Low Dose		Week 12	76.0	68.0	8.0
Xanomeline Low Dose		Week 12	76.0	70.0	6.0
Xanomeline Low Dose		Week 16	70.0	68.0	2.0
Xanomeline Low Dose		Week 16	78.0	68.0	10.0
Xanomeline Low Dose		Week 16	80.0	70.0	10.0
Xanomeline Low Dose		Week 2	72.0	68.0	4.0
Xanomeline Low Dose		Week 2	76.0	68.0	8.0
Xanomeline Low Dose		Week 2	74.0	70.0	4.0
Xanomeline Low Dose		Week 20	72.0	68.0	4.0
Xanomeline Low Dose		Week 20	80.0	68.0	12.0
Xanomeline Low Dose		Week 20	72.0	70.0	2.0
Xanomeline Low Dose		Week 24	72.0	68.0	4.0
Xanomeline Low Dose		Week 24	76.0	68.0	8.0
Xanomeline Low Dose		Week 24	70.0	70.0	0.0
Xanomeline Low Dose		Week 26	70.0	68.0	2.0
Xanomeline Low Dose		Week 26	80.0	68.0	12.0
Xanomeline Low Dose		Week 26	76.0	70.0	6.0
Xanomeline Low Dose		Week 4	72.0	68.0	4.0
Xanomeline Low Dose		Week 4	76.0	68.0	8.0
Xanomeline Low Dose		Week 4	78.0	70.0	8.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	74.0	68.0	6.0
Xanomeline Low Dose		Week 6	72.0	70.0	2.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	76.0	68.0	8.0
Xanomeline Low Dose		Week 8	76.0	70.0	6.0
Xanomeline Low Dose			76.0	68.0
Xanomeline Low Dose			80.0	68.0
Xanomeline Low Dose			76.0	70.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			82.0	68.0
Xanomeline Low Dose			82.0	70.0
Placebo		Week 12	64.0	64.0	0.0
Placebo		Week 12	70.0	68.0	2.0
Placebo		Week 12	70.0	64.0	6.0
Placebo		Week 16	62.0	64.0	-2.0
Placebo		Week 16	70.0	68.0	2.0
Placebo		Week 16	72.0	64.0	8.0
Placebo		Week 2	68.0	64.0	4.0
Placebo		Week 2	76.0	68.0	8.0
Placebo		Week 2	76.0	64.0	12.0
Placebo		Week 20	66.0	64.0	2.0
Placebo		Week 20	70.0	68.0	2.0
Placebo		Week 20	72.0	64.0	8.0
Placebo		Week 24	70.0	64.0	6.0
Placebo		Week 24	68.0	68.0	0.0
Placebo		Week 24	68.0	64.0	4.0
Placebo		Week 26	84.0	64.0	20.0
Placebo		Week 26	80.0	68.0	12.0
Placebo		Week 26	80.0	64.0	16.0
Placebo		Week 4	64.0	64.0	0.0
Placebo		Week 4	68.0	68.0	0.0
Placebo		Week 4	68.0	64.0	4.0
Placebo		Week 6	64.0	64.0	0.0
Placebo		Week 6	72.0	68.0	4.0
Placebo		Week 6	72.0	64.0	8.0
Placebo		Week 8	60.0	64.0	-4.0
Placebo		Week 8	68.0	68.0	0.0
Placebo		Week 8	66.0	64.0	2.0
Placebo			68.0	64.0
Placebo			72.0	68.0
Placebo			72.0	64.0
Placebo			68.0	64.0
Placebo			72.0	68.0
Placebo			72.0	64.0
Xanomeline Low Dose		Week 12	84.0	64.0	20.0
Xanomeline Low Dose		Week 12	78.0	68.0	10.0
Xanomeline Low Dose		Week 12	80.0	68.0	12.0
Xanomeline Low Dose		Week 16	73.0	64.0	9.0
Xanomeline Low Dose		Week 16	76.0	68.0	8.0
Xanomeline Low Dose		Week 16	80.0	68.0	12.0
Xanomeline Low Dose		Week 2	78.0	64.0	14.0
Xanomeline Low Dose		Week 2	88.0	68.0	20.0
Xanomeline Low Dose		Week 2	88.0	68.0	20.0
Xanomeline Low Dose		Week 20	69.0	64.0	5.0
Xanomeline Low Dose		Week 20	72.0	68.0	4.0
Xanomeline Low Dose		Week 20	78.0	68.0	10.0
Xanomeline Low Dose		Week 24	64.0	64.0	0.0
Xanomeline Low Dose		Week 24	74.0	68.0	6.0
Xanomeline Low Dose		Week 24	80.0	68.0	12.0
Xanomeline Low Dose		Week 26	68.0	64.0	4.0
Xanomeline Low Dose		Week 26	72.0	68.0	4.0
Xanomeline Low Dose		Week 26	76.0	68.0	8.0
Xanomeline Low Dose		Week 4	80.0	64.0	16.0
Xanomeline Low Dose		Week 4	88.0	68.0	20.0
Xanomeline Low Dose		Week 4	84.0	68.0	16.0
Xanomeline Low Dose		Week 6	74.0	64.0	10.0
Xanomeline Low Dose		Week 6	72.0	68.0	4.0
Xanomeline Low Dose		Week 6	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	72.0	64.0	8.0
Xanomeline Low Dose		Week 8	74.0	68.0	6.0
Xanomeline Low Dose		Week 8	74.0	68.0	6.0
Xanomeline Low Dose			66.0	64.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			72.0	68.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			84.0	68.0
Xanomeline Low Dose			84.0	68.0
Placebo		Week 2	66.0	70.0	-4.0
Placebo		Week 2	70.0	72.0	-2.0
Placebo		Week 2	70.0	76.0	-6.0
Placebo			60.0	70.0
Placebo			60.0	72.0
Placebo			75.0	76.0
Xanomeline High Dose		Week 2	80.0	82.0	-2.0
Xanomeline High Dose		Week 2	88.0	88.0	0.0
Xanomeline High Dose		Week 2	82.0	82.0	0.0
Xanomeline High Dose		Week 4	76.0	82.0	-6.0
Xanomeline High Dose		Week 4	76.0	88.0	-12.0
Xanomeline High Dose		Week 4	80.0	82.0	-2.0
Xanomeline High Dose		Week 6	88.0	82.0	6.0
Xanomeline High Dose		Week 6	84.0	88.0	-4.0
Xanomeline High Dose		Week 6	88.0	82.0	6.0
Xanomeline High Dose			80.0	82.0
Xanomeline High Dose			88.0	88.0
Xanomeline High Dose			84.0	82.0
Xanomeline High Dose			84.0	82.0
Xanomeline High Dose			88.0	88.0
Xanomeline High Dose			84.0	82.0
Placebo		Week 2	68.0	60.0	8.0
Placebo		Week 2	72.0	72.0	0.0
Placebo		Week 2	72.0	68.0	4.0
Placebo		Week 4	68.0	60.0	8.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	72.0	68.0	4.0
Placebo		Week 6	60.0	60.0	0.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 6	72.0	68.0	4.0
Placebo		Week 8	64.0	60.0	4.0
Placebo		Week 8	70.0	72.0	-2.0
Placebo		Week 8	68.0	68.0	0.0
Placebo			64.0	60.0
Placebo			70.0	72.0
Placebo			68.0	68.0
Placebo			64.0	60.0
Placebo			68.0	72.0
Placebo			68.0	68.0
Xanomeline High Dose		Week 2	76.0	58.0	18.0
Xanomeline High Dose		Week 2	80.0	75.0	5.0
Xanomeline High Dose		Week 2	84.0	70.0	14.0
Xanomeline High Dose		Week 4	74.0	58.0	16.0
Xanomeline High Dose		Week 4	80.0	75.0	5.0
Xanomeline High Dose		Week 4	80.0	70.0	10.0
Xanomeline High Dose		Week 6	68.0	58.0	10.0
Xanomeline High Dose		Week 6	72.0	75.0	-3.0
Xanomeline High Dose		Week 6	74.0	70.0	4.0
Xanomeline High Dose		Week 8	66.0	58.0	8.0
Xanomeline High Dose		Week 8	70.0	75.0	-5.0
Xanomeline High Dose		Week 8	72.0	70.0	2.0
Xanomeline High Dose			62.0	58.0
Xanomeline High Dose			72.0	75.0
Xanomeline High Dose			70.0	70.0
Xanomeline High Dose			72.0	58.0
Xanomeline High Dose			78.0	75.0
Xanomeline High Dose			80.0	70.0
Xanomeline Low Dose		Week 2	62.0	60.0	2.0
Xanomeline Low Dose		Week 2	68.0	64.0	4.0
Xanomeline Low Dose		Week 2	66.0	60.0	6.0
Xanomeline Low Dose		Week 4	64.0	60.0	4.0
Xanomeline Low Dose		Week 4	72.0	64.0	8.0
Xanomeline Low Dose		Week 4	68.0	60.0	8.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	66.0	64.0	2.0
Xanomeline Low Dose		Week 2	64.0	68.0	-4.0
Xanomeline Low Dose		Week 4	64.0	60.0	4.0
Xanomeline Low Dose		Week 4	68.0	64.0	4.0
Xanomeline Low Dose		Week 4	66.0	68.0	-2.0
Xanomeline Low Dose		Week 6	64.0	60.0	4.0
Xanomeline Low Dose		Week 6	70.0	64.0	6.0
Xanomeline Low Dose		Week 6	70.0	68.0	2.0
Xanomeline Low Dose		Week 8	60.0	60.0	0.0
Xanomeline Low Dose		Week 8	66.0	64.0	2.0
Xanomeline Low Dose		Week 8	66.0	68.0	-2.0
Xanomeline Low Dose			62.0	60.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			68.0	68.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			70.0	68.0
Xanomeline High Dose		Week 2	66.0	70.0	-4.0
Xanomeline High Dose		Week 2	66.0	74.0	-8.0
Xanomeline High Dose		Week 2	70.0	79.0	-9.0
Xanomeline High Dose		Week 4	81.0	70.0	11.0
Xanomeline High Dose		Week 4	81.0	74.0	7.0
Xanomeline High Dose		Week 4	80.0	79.0	1.0
Xanomeline High Dose		Week 6	75.0	70.0	5.0
Xanomeline High Dose		Week 6	82.0	74.0	8.0
Xanomeline High Dose		Week 6	78.0	79.0	-1.0
Xanomeline High Dose		Week 8	68.0	70.0	-2.0
Xanomeline High Dose		Week 8	72.0	74.0	-2.0
Xanomeline High Dose		Week 8	74.0	79.0	-5.0
Xanomeline High Dose			68.0	70.0
Xanomeline High Dose			86.0	74.0
Xanomeline High Dose			75.0	79.0
Xanomeline High Dose			81.0	70.0
Xanomeline High Dose			80.0	74.0
Xanomeline High Dose			80.0	79.0
Placebo		Week 12	74.0	70.0	4.0
Placebo		Week 12	86.0	76.0	10.0
Placebo		Week 12	72.0	72.0	0.0
Placebo		Week 16	72.0	70.0	2.0
Placebo		Week 16	72.0	76.0	-4.0
Placebo		Week 16	72.0	72.0	0.0
Placebo		Week 2	68.0	70.0	-2.0
Placebo		Week 2	72.0	76.0	-4.0
Placebo		Week 2	72.0	72.0	0.0
Placebo		Week 20	72.0	70.0	2.0
Placebo		Week 20	72.0	76.0	-4.0
Placebo		Week 20	72.0	72.0	0.0
Placebo		Week 24	76.0	70.0	6.0
Placebo		Week 24	78.0	76.0	2.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 26	74.0	70.0	4.0
Placebo		Week 26	74.0	76.0	-2.0
Placebo		Week 26	72.0	72.0	0.0
Placebo		Week 4	58.0	70.0	-12.0
Placebo		Week 4	64.0	76.0	-12.0
Placebo		Week 4	68.0	72.0	-4.0
Placebo		Week 6	56.0	70.0	-14.0
Placebo		Week 6	64.0	76.0	-12.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 8	64.0	70.0	-6.0
Placebo		Week 8	70.0	76.0	-6.0
Placebo		Week 8	72.0	72.0	0.0
Placebo			62.0	70.0
Placebo			68.0	76.0
Placebo			68.0	72.0
Placebo		Week 12	64.0	60.0	4.0
Placebo		Week 12	70.0	64.0	6.0
Placebo		Week 12	72.0	64.0	8.0
Placebo		Week 16	60.0	60.0	0.0
Placebo		Week 16	72.0	64.0	8.0
Placebo		Week 16	76.0	64.0	12.0
Placebo		Week 2	64.0	60.0	4.0
Placebo		Week 2	66.0	64.0	2.0
Placebo		Week 2	64.0	64.0	0.0
Placebo		Week 20	66.0	60.0	6.0
Placebo		Week 20	72.0	64.0	8.0
Placebo		Week 20	74.0	64.0	10.0
Placebo		Week 24	70.0	60.0	10.0
Placebo		Week 24	70.0	64.0	6.0
Placebo		Week 24	72.0	64.0	8.0
Placebo		Week 4	66.0	60.0	6.0
Placebo		Week 4	72.0	64.0	8.0
Placebo		Week 4	70.0	64.0	6.0
Placebo		Week 6	64.0	60.0	4.0
Placebo		Week 6	70.0	64.0	6.0
Placebo		Week 6	70.0	64.0	6.0
Placebo		Week 8	68.0	60.0	8.0
Placebo		Week 8	72.0	64.0	8.0
Placebo		Week 8	72.0	64.0	8.0
Placebo			60.0	60.0
Placebo			64.0	64.0
Placebo			60.0	64.0
Placebo			64.0	60.0
Placebo			68.0	64.0
Placebo			68.0	64.0
Placebo		Week 2	68.0	72.0	-4.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	72.0	78.0	-6.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	82.0	80.0	2.0
Placebo		Week 4	82.0	78.0	4.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	76.0	80.0	-4.0
Placebo		Week 6	76.0	78.0	-2.0
Placebo			88.0	72.0
Placebo			92.0	80.0
Placebo			90.0	78.0
Placebo		Week 12	70.0	74.0	-4.0
Placebo		Week 12	78.0	80.0	-2.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 16	78.0	74.0	4.0
Placebo		Week 16	78.0	80.0	-2.0
Placebo		Week 16	78.0	80.0	-2.0
Placebo		Week 2	80.0	74.0	6.0
Placebo		Week 2	86.0	80.0	6.0
Placebo		Week 2	84.0	80.0	4.0
Placebo		Week 20	68.0	74.0	-6.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 20	76.0	80.0	-4.0
Placebo		Week 4	76.0	74.0	2.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 6	72.0	74.0	-2.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	76.0	80.0	-4.0
Placebo		Week 8	74.0	74.0	0.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			80.0	74.0
Placebo			84.0	80.0
Placebo			84.0	80.0
Placebo			74.0	74.0
Placebo			80.0	80.0
Placebo			80.0	80.0
Xanomeline Low Dose		Week 2	70.0	72.0	-2.0
Xanomeline Low Dose		Week 2	70.0	70.0	0.0
Xanomeline Low Dose		Week 2	68.0	67.0	1.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			70.0	70.0
Xanomeline Low Dose			68.0	67.0
Placebo		Week 12	90.0	84.0	6.0
Placebo		Week 12	90.0	88.0	2.0
Placebo		Week 12	90.0	82.0	8.0
Placebo		Week 16	68.0	84.0	-16.0
Placebo		Week 16	70.0	88.0	-18.0
Placebo		Week 16	70.0	82.0	-12.0
Placebo		Week 2	80.0	84.0	-4.0
Placebo		Week 2	80.0	88.0	-8.0
Placebo		Week 2	80.0	82.0	-2.0
Placebo		Week 4	88.0	84.0	4.0
Placebo		Week 4	92.0	88.0	4.0
Placebo		Week 4	92.0	82.0	10.0
Placebo		Week 6	60.0	84.0	-24.0
Placebo		Week 6	60.0	88.0	-28.0
Placebo		Week 6	62.0	82.0	-20.0
Placebo		Week 8	72.0	84.0	-12.0
Placebo		Week 8	72.0	88.0	-16.0
Placebo		Week 8	70.0	82.0	-12.0
Placebo			64.0	84.0
Placebo			64.0	88.0
Placebo			64.0	82.0
Placebo			72.0	84.0
Placebo			74.0	88.0
Placebo			76.0	82.0
Placebo		Week 2	61.0	60.0	1.0
Placebo		Week 2	80.0	62.0	18.0
Placebo		Week 2	80.0	60.0	20.0
Placebo			62.0	60.0
Placebo			64.0	62.0
Placebo			64.0	60.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	88.0	78.0	10.0
Xanomeline High Dose		Week 16	68.0	80.0	-12.0
Xanomeline High Dose		Week 16	68.0	78.0	-10.0
Xanomeline High Dose		Week 16	70.0	78.0	-8.0
Xanomeline High Dose		Week 2	62.0	80.0	-18.0
Xanomeline High Dose		Week 2	60.0	78.0	-18.0
Xanomeline High Dose		Week 2	60.0	78.0	-18.0
Xanomeline High Dose		Week 20	84.0	80.0	4.0
Xanomeline High Dose		Week 20	88.0	78.0	10.0
Xanomeline High Dose		Week 20	88.0	78.0	10.0
Xanomeline High Dose		Week 24	74.0	80.0	-6.0
Xanomeline High Dose		Week 24	70.0	78.0	-8.0
Xanomeline High Dose		Week 24	70.0	78.0	-8.0
Xanomeline High Dose		Week 26	68.0	80.0	-12.0
Xanomeline High Dose		Week 26	72.0	78.0	-6.0
Xanomeline High Dose		Week 26	72.0	78.0	-6.0
Xanomeline High Dose		Week 4	96.0	80.0	16.0
Xanomeline High Dose		Week 4	94.0	78.0	16.0
Xanomeline High Dose		Week 4	92.0	78.0	14.0
Xanomeline High Dose		Week 6	72.0	80.0	-8.0
Xanomeline High Dose		Week 6	76.0	78.0	-2.0
Xanomeline High Dose		Week 6	72.0	78.0	-6.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose		Week 8	80.0	78.0	2.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			71.0	78.0
Xanomeline High Dose			70.0	78.0
Xanomeline High Dose			100.0	80.0
Xanomeline High Dose			100.0	78.0
Xanomeline High Dose			100.0	78.0
Xanomeline High Dose		Week 12	80.0	60.0	20.0
Xanomeline High Dose		Week 12	84.0	64.0	20.0
Xanomeline High Dose		Week 12	84.0	62.0	22.0
Xanomeline High Dose		Week 2	64.0	60.0	4.0
Xanomeline High Dose		Week 2	62.0	64.0	-2.0
Xanomeline High Dose		Week 2	62.0	62.0	0.0
Xanomeline High Dose		Week 4	62.0	60.0	2.0
Xanomeline High Dose		Week 4	60.0	64.0	-4.0
Xanomeline High Dose		Week 4	62.0	62.0	0.0
Xanomeline High Dose		Week 6	64.0	60.0	4.0
Xanomeline High Dose		Week 6	64.0	64.0	0.0
Xanomeline High Dose		Week 6	60.0	62.0	-2.0
Xanomeline High Dose		Week 8	64.0	60.0	4.0
Xanomeline High Dose		Week 8	68.0	64.0	4.0
Xanomeline High Dose		Week 8	64.0	62.0	2.0
Xanomeline High Dose			68.0	60.0
Xanomeline High Dose			62.0	64.0
Xanomeline High Dose			62.0	62.0
Xanomeline High Dose			64.0	60.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			66.0	62.0
Placebo		Week 12	80.0	78.0	2.0
Placebo		Week 12	84.0	78.0	6.0
Placebo		Week 12	84.0	78.0	6.0
Placebo		Week 16	62.0	78.0	-16.0
Placebo		Week 16	64.0	78.0	-14.0
Placebo		Week 16	64.0	78.0	-14.0
Placebo		Week 2	62.0	78.0	-16.0
Placebo		Week 2	64.0	78.0	-14.0
Placebo		Week 2	64.0	78.0	-14.0
Placebo		Week 20	72.0	78.0	-6.0
Placebo		Week 20	72.0	78.0	-6.0
Placebo		Week 20	70.0	78.0	-8.0
Placebo		Week 24	84.0	78.0	6.0
Placebo		Week 24	84.0	78.0	6.0
Placebo		Week 24	82.0	78.0	4.0
Placebo		Week 26	78.0	78.0	0.0
Placebo		Week 26	74.0	78.0	-4.0
Placebo		Week 26	78.0	78.0	0.0
Placebo		Week 4	84.0	78.0	6.0
Placebo		Week 4	88.0	78.0	10.0
Placebo		Week 4	86.0	78.0	8.0
Placebo		Week 6	71.0	78.0	-7.0
Placebo		Week 6	72.0	78.0	-6.0
Placebo		Week 6	70.0	78.0	-8.0
Placebo		Week 8	72.0	78.0	-6.0
Placebo		Week 8	72.0	78.0	-6.0
Placebo		Week 8	72.0	78.0	-6.0
Placebo			62.0	78.0
Placebo			61.0	78.0
Placebo			60.0	78.0
Placebo			80.0	78.0
Placebo			88.0	78.0
Placebo			84.0	78.0
Xanomeline Low Dose		Week 12	72.0	78.0	-6.0
Xanomeline Low Dose		Week 12	84.0	80.0	4.0
Xanomeline Low Dose		Week 12	80.0	78.0	2.0
Xanomeline Low Dose		Week 16	68.0	78.0	-10.0
Xanomeline Low Dose		Week 16	74.0	80.0	-6.0
Xanomeline Low Dose		Week 16	74.0	78.0	-4.0
Xanomeline Low Dose		Week 2	69.0	78.0	-9.0
Xanomeline Low Dose		Week 2	72.0	80.0	-8.0
Xanomeline Low Dose		Week 2	70.0	78.0	-8.0
Xanomeline Low Dose		Week 20	78.0	78.0	0.0
Xanomeline Low Dose		Week 20	80.0	80.0	0.0
Xanomeline Low Dose		Week 20	78.0	78.0	0.0
Xanomeline Low Dose		Week 24	68.0	78.0	-10.0
Xanomeline Low Dose		Week 24	68.0	80.0	-12.0
Xanomeline Low Dose		Week 24	68.0	78.0	-10.0
Xanomeline Low Dose		Week 4	64.0	78.0	-14.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	72.0	78.0	-6.0
Xanomeline Low Dose		Week 6	82.0	78.0	4.0
Xanomeline Low Dose		Week 6	84.0	80.0	4.0
Xanomeline Low Dose		Week 6	82.0	78.0	4.0
Xanomeline Low Dose		Week 8	72.0	78.0	-6.0
Xanomeline Low Dose		Week 8	64.0	80.0	-16.0
Xanomeline Low Dose		Week 8	64.0	78.0	-14.0
Xanomeline Low Dose			68.0	78.0
Xanomeline Low Dose			68.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			68.0	78.0
Xanomeline Low Dose			69.0	80.0
Xanomeline Low Dose			70.0	78.0
Xanomeline High Dose		Week 2	80.0	68.0	12.0
Xanomeline High Dose		Week 2	84.0	64.0	20.0
Xanomeline High Dose		Week 2	84.0	68.0	16.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose		Week 12	72.0	64.0	8.0
Xanomeline High Dose		Week 12	72.0	64.0	8.0
Xanomeline High Dose		Week 12	70.0	62.0	8.0
Xanomeline High Dose		Week 2	80.0	64.0	16.0
Xanomeline High Dose		Week 2	81.0	64.0	17.0
Xanomeline High Dose		Week 2	80.0	62.0	18.0
Xanomeline High Dose		Week 4	64.0	64.0	0.0
Xanomeline High Dose		Week 4	68.0	64.0	4.0
Xanomeline High Dose		Week 4	68.0	62.0	6.0
Xanomeline High Dose		Week 6	68.0	64.0	4.0
Xanomeline High Dose		Week 6	80.0	64.0	16.0
Xanomeline High Dose		Week 6	80.0	62.0	18.0
Xanomeline High Dose		Week 8	60.0	64.0	-4.0
Xanomeline High Dose		Week 8	72.0	64.0	8.0
Xanomeline High Dose		Week 8	68.0	62.0	6.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			67.0	62.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			68.0	62.0
Placebo		Week 12	70.0	68.0	2.0
Placebo		Week 12	70.0	68.0	2.0
Placebo		Week 12	68.0	68.0	0.0
Placebo		Week 16	80.0	68.0	12.0
Placebo		Week 16	80.0	68.0	12.0
Placebo		Week 16	80.0	68.0	12.0
Placebo		Week 2	64.0	68.0	-4.0
Placebo		Week 2	60.0	68.0	-8.0
Placebo		Week 2	60.0	68.0	-8.0
Placebo		Week 20	68.0	68.0	0.0
Placebo		Week 20	68.0	68.0	0.0
Placebo		Week 20	70.0	68.0	2.0
Placebo		Week 24	72.0	68.0	4.0
Placebo		Week 24	76.0	68.0	8.0
Placebo		Week 24	76.0	68.0	8.0
Placebo		Week 26	72.0	68.0	4.0
Placebo		Week 26	72.0	68.0	4.0
Placebo		Week 26	70.0	68.0	2.0
Placebo		Week 4	80.0	68.0	12.0
Placebo		Week 4	78.0	68.0	10.0
Placebo		Week 4	78.0	68.0	10.0
Placebo		Week 6	72.0	68.0	4.0
Placebo		Week 6	70.0	68.0	2.0
Placebo		Week 6	68.0	68.0	0.0
Placebo		Week 8	72.0	68.0	4.0
Placebo		Week 8	70.0	68.0	2.0
Placebo		Week 8	70.0	68.0	2.0
Placebo			62.0	68.0
Placebo			64.0	68.0
Placebo			64.0	68.0
Xanomeline High Dose		Week 2	78.0	64.0	14.0
Xanomeline High Dose		Week 2	78.0	68.0	10.0
Xanomeline High Dose		Week 2	80.0	68.0	12.0
Xanomeline High Dose			80.0	64.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			80.0	68.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 16	68.0	68.0	0.0
Xanomeline Low Dose		Week 16	68.0	68.0	0.0
Xanomeline Low Dose		Week 16	69.0	68.0	1.0
Xanomeline Low Dose		Week 2	74.0	68.0	6.0
Xanomeline Low Dose		Week 2	70.0	68.0	2.0
Xanomeline Low Dose		Week 2	71.0	68.0	3.0
Xanomeline Low Dose		Week 4	78.0	68.0	10.0
Xanomeline Low Dose		Week 4	80.0	68.0	12.0
Xanomeline Low Dose		Week 4	81.0	68.0	13.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	72.0	68.0	4.0
Xanomeline Low Dose		Week 6	70.0	68.0	2.0
Xanomeline Low Dose		Week 8	98.0	68.0	30.0
Xanomeline Low Dose		Week 8	95.0	68.0	27.0
Xanomeline Low Dose		Week 8	98.0	68.0	30.0
Xanomeline Low Dose			84.0	68.0
Xanomeline Low Dose			80.0	68.0
Xanomeline Low Dose			78.0	68.0
Xanomeline Low Dose			80.0	68.0
Xanomeline Low Dose			81.0	68.0
Xanomeline Low Dose			82.0	68.0
Xanomeline Low Dose		Week 12	60.0	64.0	-4.0
Xanomeline Low Dose		Week 12	64.0	66.0	-2.0
Xanomeline Low Dose		Week 12	60.0	62.0	-2.0
Xanomeline Low Dose		Week 16	64.0	64.0	0.0
Xanomeline Low Dose		Week 16	68.0	66.0	2.0
Xanomeline Low Dose		Week 16	68.0	62.0	6.0
Xanomeline Low Dose		Week 2	70.0	64.0	6.0
Xanomeline Low Dose		Week 2	72.0	66.0	6.0
Xanomeline Low Dose		Week 2	70.0	62.0	8.0
Xanomeline Low Dose		Week 20	68.0	64.0	4.0
Xanomeline Low Dose		Week 20	68.0	66.0	2.0
Xanomeline Low Dose		Week 20	70.0	62.0	8.0
Xanomeline Low Dose		Week 24	64.0	64.0	0.0
Xanomeline Low Dose		Week 24	68.0	66.0	2.0
Xanomeline Low Dose		Week 24	60.0	62.0	-2.0
Xanomeline Low Dose		Week 26	62.0	64.0	-2.0
Xanomeline Low Dose		Week 26	64.0	66.0	-2.0
Xanomeline Low Dose		Week 26	68.0	62.0	6.0
Xanomeline Low Dose		Week 4	62.0	64.0	-2.0
Xanomeline Low Dose		Week 4	64.0	66.0	-2.0
Xanomeline Low Dose		Week 4	64.0	62.0	2.0
Xanomeline Low Dose		Week 6	74.0	64.0	10.0
Xanomeline Low Dose		Week 6	72.0	66.0	6.0
Xanomeline Low Dose		Week 6	74.0	62.0	12.0
Xanomeline Low Dose		Week 8	60.0	64.0	-4.0
Xanomeline Low Dose		Week 8	62.0	66.0	-4.0
Xanomeline Low Dose		Week 8	60.0	62.0	-2.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			80.0	66.0
Xanomeline Low Dose			80.0	62.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			68.0	66.0
Xanomeline Low Dose			68.0	62.0
Placebo		Week 12	74.0	80.0	-6.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	71.0	80.0	-9.0
Placebo		Week 16	70.0	80.0	-10.0
Placebo		Week 16	83.0	80.0	3.0
Placebo		Week 16	79.0	80.0	-1.0
Placebo		Week 2	70.0	80.0	-10.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 20	73.0	80.0	-7.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 20	70.0	80.0	-10.0
Placebo		Week 24	71.0	80.0	-9.0
Placebo		Week 24	56.0	80.0	-24.0
Placebo		Week 24	73.0	80.0	-7.0
Placebo		Week 4	78.0	80.0	-2.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 6	78.0	80.0	-2.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	78.0	80.0	-2.0
Placebo		Week 8	64.0	80.0	-16.0
Placebo		Week 8	66.0	80.0	-14.0
Placebo		Week 8	64.0	80.0	-16.0
Placebo			72.0	80.0
Placebo			78.0	80.0
Placebo			72.0	80.0
Placebo			80.0	80.0
Placebo			88.0	80.0
Placebo			86.0	80.0
Xanomeline High Dose		Week 2	80.0	84.0	-4.0
Xanomeline High Dose		Week 2	88.0	88.0	0.0
Xanomeline High Dose		Week 2	88.0	84.0	4.0
Xanomeline High Dose		Week 4	88.0	84.0	4.0
Xanomeline High Dose		Week 4	88.0	88.0	0.0
Xanomeline High Dose		Week 4	90.0	84.0	6.0
Xanomeline High Dose			84.0	84.0
Xanomeline High Dose			88.0	88.0
Xanomeline High Dose			86.0	84.0
Xanomeline High Dose			90.0	84.0
Xanomeline High Dose			94.0	88.0
Xanomeline High Dose			94.0	84.0
Placebo		Week 12	60.0	60.0	0.0
Placebo		Week 12	64.0	68.0	-4.0
Placebo		Week 12	64.0	66.0	-2.0
Placebo		Week 16	60.0	60.0	0.0
Placebo		Week 16	64.0	68.0	-4.0
Placebo		Week 16	60.0	66.0	-6.0
Placebo		Week 2	60.0	60.0	0.0
Placebo		Week 2	64.0	68.0	-4.0
Placebo		Week 2	68.0	66.0	2.0
Placebo		Week 20	56.0	60.0	-4.0
Placebo		Week 20	60.0	68.0	-8.0
Placebo		Week 20	64.0	66.0	-2.0
Placebo		Week 24	56.0	60.0	-4.0
Placebo		Week 24	60.0	68.0	-8.0
Placebo		Week 24	60.0	66.0	-6.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 4	62.0	68.0	-6.0
Placebo		Week 4	66.0	66.0	0.0
Placebo		Week 6	56.0	60.0	-4.0
Placebo		Week 6	60.0	68.0	-8.0
Placebo		Week 6	64.0	66.0	-2.0
Placebo		Week 8	56.0	60.0	-4.0
Placebo		Week 8	60.0	68.0	-8.0
Placebo		Week 8	56.0	66.0	-10.0
Placebo			60.0	60.0
Placebo			58.0	68.0
Placebo			60.0	66.0
Placebo			54.0	60.0
Placebo			56.0	68.0
Placebo			52.0	66.0
Xanomeline Low Dose		Week 2	77.0	84.0	-7.0
Xanomeline Low Dose		Week 2	102.0	100.0	2.0
Xanomeline Low Dose		Week 2	97.0	100.0	-3.0
Xanomeline Low Dose			80.0	84.0
Xanomeline Low Dose			96.0	100.0
Xanomeline Low Dose			92.0	100.0
Xanomeline Low Dose		Week 12	62.0	88.0	-26.0
Xanomeline Low Dose		Week 12	70.0	84.0	-14.0
Xanomeline Low Dose		Week 12	78.0	84.0	-6.0
Xanomeline Low Dose		Week 16	60.0	88.0	-28.0
Xanomeline Low Dose		Week 16	68.0	84.0	-16.0
Xanomeline Low Dose		Week 16	64.0	84.0	-20.0
Xanomeline Low Dose		Week 2	60.0	88.0	-28.0
Xanomeline Low Dose		Week 2	72.0	84.0	-12.0
Xanomeline Low Dose		Week 2	66.0	84.0	-18.0
Xanomeline Low Dose		Week 20	84.0	88.0	-4.0
Xanomeline Low Dose		Week 20	88.0	84.0	4.0
Xanomeline Low Dose		Week 20	92.0	84.0	8.0
Xanomeline Low Dose		Week 24	72.0	88.0	-16.0
Xanomeline Low Dose		Week 24	80.0	84.0	-4.0
Xanomeline Low Dose		Week 24	82.0	84.0	-2.0
Xanomeline Low Dose		Week 26	64.0	88.0	-24.0
Xanomeline Low Dose		Week 26	72.0	84.0	-12.0
Xanomeline Low Dose		Week 26	60.0	84.0	-24.0
Xanomeline Low Dose		Week 4	70.0	88.0	-18.0
Xanomeline Low Dose		Week 4	78.0	84.0	-6.0
Xanomeline Low Dose		Week 4	78.0	84.0	-6.0
Xanomeline Low Dose		Week 6	60.0	88.0	-28.0
Xanomeline Low Dose		Week 6	72.0	84.0	-12.0
Xanomeline Low Dose		Week 6	76.0	84.0	-8.0
Xanomeline Low Dose		Week 8	62.0	88.0	-26.0
Xanomeline Low Dose		Week 8	74.0	84.0	-10.0
Xanomeline Low Dose		Week 8	70.0	84.0	-14.0
Xanomeline Low Dose			60.0	88.0
Xanomeline Low Dose			88.0	84.0
Xanomeline Low Dose			70.0	84.0
Xanomeline Low Dose			66.0	88.0
Xanomeline Low Dose			72.0	84.0
Xanomeline Low Dose			66.0	84.0
Placebo		Week 12	72.0	62.0	10.0
Placebo		Week 12	84.0	66.0	18.0
Placebo		Week 12	72.0	62.0	10.0
Placebo		Week 16	60.0	62.0	-2.0
Placebo		Week 16	56.0	66.0	-10.0
Placebo		Week 16	64.0	62.0	2.0
Placebo		Week 2	80.0	62.0	18.0
Placebo		Week 2	82.0	66.0	16.0
Placebo		Week 2	80.0	62.0	18.0
Placebo		Week 20	64.0	62.0	2.0
Placebo		Week 20	66.0	66.0	0.0
Placebo		Week 20	60.0	62.0	-2.0
Placebo		Week 24	60.0	62.0	-2.0
Placebo		Week 24	72.0	66.0	6.0
Placebo		Week 24	72.0	62.0	10.0
Placebo		Week 26	68.0	62.0	6.0
Placebo		Week 26	64.0	66.0	-2.0
Placebo		Week 26	60.0	62.0	-2.0
Placebo		Week 4	78.0	62.0	16.0
Placebo		Week 4	80.0	66.0	14.0
Placebo		Week 4	82.0	62.0	20.0
Placebo		Week 6	74.0	62.0	12.0
Placebo		Week 6	66.0	66.0	0.0
Placebo		Week 6	72.0	62.0	10.0
Placebo		Week 8	60.0	62.0	-2.0
Placebo		Week 8	68.0	66.0	2.0
Placebo		Week 8	60.0	62.0	-2.0
Placebo			72.0	62.0
Placebo			60.0	66.0
Placebo			72.0	62.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	94.0	104.0	-10.0
Placebo		Week 2	96.0	80.0	16.0
Placebo		Week 4	92.0	88.0	4.0
Placebo		Week 4	100.0	104.0	-4.0
Placebo		Week 4	96.0	80.0	16.0
Placebo			70.0	88.0
Placebo			68.0	104.0
Placebo			72.0	80.0
Placebo			84.0	88.0
Placebo			86.0	104.0
Placebo			80.0	80.0
Placebo		Week 12	70.0	80.0	-10.0
Placebo		Week 12	80.0	78.0	2.0
Placebo		Week 12	82.0	80.0	2.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	76.0	78.0	-2.0
Placebo		Week 16	72.0	80.0	-8.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 2	84.0	78.0	6.0
Placebo		Week 2	84.0	80.0	4.0
Placebo		Week 20	78.0	80.0	-2.0
Placebo		Week 20	76.0	78.0	-2.0
Placebo		Week 20	78.0	80.0	-2.0
Placebo		Week 24	70.0	80.0	-10.0
Placebo		Week 24	64.0	78.0	-14.0
Placebo		Week 24	72.0	80.0	-8.0
Placebo		Week 26	72.0	80.0	-8.0
Placebo		Week 26	72.0	78.0	-6.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 4	78.0	78.0	0.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 6	80.0	78.0	2.0
Placebo		Week 6	80.0	80.0	0.0
Placebo		Week 8	84.0	80.0	4.0
Placebo		Week 8	82.0	78.0	4.0
Placebo		Week 8	80.0	80.0	0.0
Placebo			68.0	80.0
Placebo			68.0	78.0
Placebo			70.0	80.0
Placebo			66.0	80.0
Placebo			72.0	78.0
Placebo			72.0	80.0
Xanomeline High Dose		Week 12	74.0	72.0	2.0
Xanomeline High Dose		Week 12	70.0	68.0	2.0
Xanomeline High Dose		Week 12	76.0	74.0	2.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 2	78.0	74.0	4.0
Xanomeline High Dose		Week 4	62.0	72.0	-10.0
Xanomeline High Dose		Week 4	68.0	68.0	0.0
Xanomeline High Dose		Week 4	78.0	74.0	4.0
Xanomeline High Dose		Week 6	66.0	72.0	-6.0
Xanomeline High Dose		Week 6	66.0	68.0	-2.0
Xanomeline High Dose		Week 6	66.0	74.0	-8.0
Xanomeline High Dose		Week 8	72.0	72.0	0.0
Xanomeline High Dose		Week 8	80.0	68.0	12.0
Xanomeline High Dose		Week 8	76.0	74.0	2.0
Xanomeline High Dose			64.0	72.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			72.0	74.0
Xanomeline High Dose			66.0	72.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			70.0	74.0
Xanomeline Low Dose		Week 2	99.0	80.0	19.0
Xanomeline Low Dose		Week 2	88.0	88.0	0.0
Xanomeline Low Dose		Week 2	95.0	88.0	7.0
Xanomeline High Dose		Week 2	80.0	74.0	6.0
Xanomeline High Dose		Week 2	90.0	100.0	-10.0
Xanomeline High Dose		Week 2	90.0	88.0	2.0
Xanomeline High Dose		Week 4	72.0	74.0	-2.0
Xanomeline High Dose		Week 4	84.0	100.0	-16.0
Xanomeline High Dose		Week 4	78.0	88.0	-10.0
Xanomeline High Dose			72.0	74.0
Xanomeline High Dose			90.0	100.0
Xanomeline High Dose			78.0	88.0
Xanomeline High Dose			82.0	74.0
Xanomeline High Dose			96.0	100.0
Xanomeline High Dose			100.0	88.0
Placebo		Week 12	82.0	86.0	-4.0
Placebo		Week 12	106.0	133.0	-27.0
Placebo		Week 12	106.0	134.0	-28.0
Placebo		Week 16	78.0	86.0	-8.0
Placebo		Week 16	84.0	133.0	-49.0
Placebo		Week 16	84.0	134.0	-50.0
Placebo		Week 2	74.0	86.0	-12.0
Placebo		Week 2	80.0	133.0	-53.0
Placebo		Week 2	88.0	134.0	-46.0
Placebo		Week 20	70.0	86.0	-16.0
Placebo		Week 20	66.0	133.0	-67.0
Placebo		Week 20	68.0	134.0	-66.0
Placebo		Week 24	84.0	86.0	-2.0
Placebo		Week 24	80.0	133.0	-53.0
Placebo		Week 24	88.0	134.0	-46.0
Placebo		Week 26	88.0	86.0	2.0
Placebo		Week 26	88.0	133.0	-45.0
Placebo		Week 26	88.0	134.0	-46.0
Placebo		Week 4	88.0	86.0	2.0
Placebo		Week 4	120.0	133.0	-13.0
Placebo		Week 4	120.0	134.0	-14.0
Placebo		Week 6	66.0	86.0	-20.0
Placebo		Week 6	68.0	133.0	-65.0
Placebo		Week 6	70.0	134.0	-64.0
Placebo		Week 8	66.0	86.0	-20.0
Placebo		Week 8	66.0	133.0	-67.0
Placebo		Week 8	60.0	134.0	-74.0
Placebo			76.0	86.0
Placebo			90.0	133.0
Placebo			90.0	134.0
Placebo			80.0	86.0
Placebo			122.0	133.0
Placebo			110.0	134.0
Xanomeline Low Dose		Week 2	52.0	58.0	-6.0
Xanomeline Low Dose		Week 2	58.0	58.0	0.0
Xanomeline Low Dose		Week 2	52.0	58.0	-6.0
Xanomeline Low Dose		Week 4	64.0	58.0	6.0
Xanomeline Low Dose		Week 4	48.0	58.0	-10.0
Xanomeline Low Dose		Week 4	48.0	58.0	-10.0
Xanomeline Low Dose		Week 6	60.0	58.0	2.0
Xanomeline Low Dose		Week 6	62.0	58.0	4.0
Xanomeline Low Dose		Week 6	76.0	58.0	18.0
Xanomeline Low Dose			52.0	58.0
Xanomeline Low Dose			60.0	58.0
Xanomeline Low Dose			64.0	58.0
Xanomeline Low Dose			60.0	58.0
Xanomeline Low Dose			64.0	58.0
Xanomeline Low Dose			60.0	58.0
Placebo		Week 12	60.0	62.0	-2.0
Placebo		Week 12	84.0	60.0	24.0
Placebo		Week 12	92.0	62.0	30.0
Placebo		Week 16	60.0	62.0	-2.0
Placebo		Week 16	60.0	60.0	0.0
Placebo		Week 16	66.0	62.0	4.0
Placebo		Week 2	80.0	62.0	18.0
Placebo		Week 2	94.0	60.0	34.0
Placebo		Week 2	80.0	62.0	18.0
Placebo		Week 20	60.0	62.0	-2.0
Placebo		Week 20	72.0	60.0	12.0
Placebo		Week 20	76.0	62.0	14.0
Placebo		Week 24	68.0	62.0	6.0
Placebo		Week 24	64.0	60.0	4.0
Placebo		Week 24	72.0	62.0	10.0
Placebo		Week 26	80.0	62.0	18.0
Placebo		Week 26	82.0	60.0	22.0
Placebo		Week 26	80.0	62.0	18.0
Placebo		Week 4	88.0	62.0	26.0
Placebo		Week 4	80.0	60.0	20.0
Placebo		Week 4	92.0	62.0	30.0
Placebo		Week 6	58.0	62.0	-4.0
Placebo		Week 6	88.0	60.0	28.0
Placebo		Week 6	78.0	62.0	16.0
Placebo		Week 8	60.0	62.0	-2.0
Placebo		Week 8	78.0	60.0	18.0
Placebo		Week 8	72.0	62.0	10.0
Placebo			76.0	62.0
Placebo			96.0	60.0
Placebo			102.0	62.0
Placebo			72.0	62.0
Placebo			72.0	60.0
Placebo			78.0	62.0
Placebo		Week 12	76.0	80.0	-4.0
Placebo		Week 12	88.0	96.0	-8.0
Placebo		Week 12	80.0	88.0	-8.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 16	88.0	96.0	-8.0
Placebo		Week 16	84.0	88.0	-4.0
Placebo		Week 2	78.0	80.0	-2.0
Placebo		Week 2	82.0	96.0	-14.0
Placebo		Week 2	80.0	88.0	-8.0
Placebo		Week 20	80.0	80.0	0.0
Placebo		Week 20	96.0	96.0	0.0
Placebo		Week 20	84.0	88.0	-4.0
Placebo		Week 24	76.0	80.0	-4.0
Placebo		Week 24	88.0	96.0	-8.0
Placebo		Week 24	76.0	88.0	-12.0
Placebo		Week 26	94.0	80.0	14.0
Placebo		Week 26	90.0	96.0	-6.0
Placebo		Week 26	88.0	88.0	0.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	92.0	96.0	-4.0
Placebo		Week 4	96.0	88.0	8.0
Placebo		Week 6	66.0	80.0	-14.0
Placebo		Week 6	72.0	96.0	-24.0
Placebo		Week 6	72.0	88.0	-16.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	80.0	96.0	-16.0
Placebo		Week 8	74.0	88.0	-14.0
Placebo			88.0	80.0
Placebo			90.0	96.0
Placebo			94.0	88.0
Placebo			80.0	80.0
Placebo			88.0	96.0
Placebo			80.0	88.0
Xanomeline Low Dose		Week 12	72.0	62.0	10.0
Xanomeline Low Dose		Week 12	88.0	70.0	18.0
Xanomeline Low Dose		Week 12	84.0	68.0	16.0
Xanomeline Low Dose		Week 2	80.0	62.0	18.0
Xanomeline Low Dose		Week 2	92.0	70.0	22.0
Xanomeline Low Dose		Week 2	90.0	68.0	22.0
Xanomeline Low Dose		Week 4	70.0	62.0	8.0
Xanomeline Low Dose		Week 4	72.0	70.0	2.0
Xanomeline Low Dose		Week 4	74.0	68.0	6.0
Xanomeline Low Dose		Week 6	64.0	62.0	2.0
Xanomeline Low Dose		Week 6	80.0	70.0	10.0
Xanomeline Low Dose		Week 6	78.0	68.0	10.0
Xanomeline Low Dose		Week 8	66.0	62.0	4.0
Xanomeline Low Dose		Week 8	74.0	70.0	4.0
Xanomeline Low Dose		Week 8	68.0	68.0	0.0
Xanomeline Low Dose			76.0	62.0
Xanomeline Low Dose			77.0	70.0
Xanomeline Low Dose			78.0	68.0
Xanomeline Low Dose			60.0	62.0
Xanomeline Low Dose			74.0	70.0
Xanomeline Low Dose			70.0	68.0
Placebo		Week 12	78.0	72.0	6.0
Placebo		Week 12	80.0	88.0	-8.0
Placebo		Week 12	82.0	72.0	10.0
Placebo		Week 16	64.0	72.0	-8.0
Placebo		Week 16	74.0	88.0	-14.0
Placebo		Week 16	80.0	72.0	8.0
Placebo		Week 2	74.0	72.0	2.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	82.0	72.0	10.0
Placebo		Week 20	88.0	72.0	16.0
Placebo		Week 20	80.0	88.0	-8.0
Placebo		Week 20	80.0	72.0	8.0
Placebo		Week 24	64.0	72.0	-8.0
Placebo		Week 24	76.0	88.0	-12.0
Placebo		Week 24	84.0	72.0	12.0
Placebo		Week 26	68.0	72.0	-4.0
Placebo		Week 26	80.0	88.0	-8.0
Placebo		Week 26	90.0	72.0	18.0
Placebo		Week 4	76.0	72.0	4.0
Placebo		Week 4	80.0	88.0	-8.0
Placebo		Week 4	88.0	72.0	16.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	92.0	88.0	4.0
Placebo		Week 6	88.0	72.0	16.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 12	64.0	64.0	0.0
Xanomeline High Dose		Week 12	84.0	70.0	14.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 16	60.0	64.0	-4.0
Xanomeline High Dose		Week 16	64.0	70.0	-6.0
Xanomeline High Dose		Week 16	72.0	80.0	-8.0
Xanomeline High Dose		Week 2	70.0	64.0	6.0
Xanomeline High Dose		Week 2	72.0	70.0	2.0
Xanomeline High Dose		Week 2	78.0	80.0	-2.0
Xanomeline High Dose		Week 20	76.0	64.0	12.0
Xanomeline High Dose		Week 20	88.0	70.0	18.0
Xanomeline High Dose		Week 20	90.0	80.0	10.0
Xanomeline High Dose		Week 24	80.0	64.0	16.0
Xanomeline High Dose		Week 24	84.0	70.0	14.0
Xanomeline High Dose		Week 24	84.0	80.0	4.0
Xanomeline High Dose		Week 26	56.0	64.0	-8.0
Xanomeline High Dose		Week 26	60.0	70.0	-10.0
Xanomeline High Dose		Week 26	60.0	80.0	-20.0
Xanomeline High Dose		Week 4	64.0	64.0	0.0
Xanomeline High Dose		Week 4	68.0	70.0	-2.0
Xanomeline High Dose		Week 4	84.0	80.0	4.0
Xanomeline High Dose		Week 6	60.0	64.0	-4.0
Xanomeline High Dose		Week 6	72.0	70.0	2.0
Xanomeline High Dose		Week 6	70.0	80.0	-10.0
Xanomeline High Dose		Week 8	60.0	64.0	-4.0
Xanomeline High Dose		Week 8	66.0	70.0	-4.0
Xanomeline High Dose		Week 8	68.0	80.0	-12.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			72.0	70.0
Xanomeline High Dose			70.0	80.0
Xanomeline High Dose			80.0	64.0
Xanomeline High Dose			82.0	70.0
Xanomeline High Dose			80.0	80.0
Placebo		Week 12	80.0	72.0	8.0
Placebo		Week 12	88.0	72.0	16.0
Placebo		Week 12	88.0	72.0	16.0
Placebo		Week 16	64.0	72.0	-8.0
Placebo		Week 16	64.0	72.0	-8.0
Placebo		Week 16	76.0	72.0	4.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 20	63.0	72.0	-9.0
Placebo		Week 20	74.0	72.0	2.0
Placebo		Week 20	72.0	72.0	0.0
Placebo		Week 24	72.0	72.0	0.0
Placebo		Week 24	70.0	72.0	-2.0
Placebo		Week 24	72.0	72.0	0.0
Placebo		Week 26	60.0	72.0	-12.0
Placebo		Week 26	64.0	72.0	-8.0
Placebo		Week 26	68.0	72.0	-4.0
Placebo		Week 4	76.0	72.0	4.0
Placebo		Week 4	80.0	72.0	8.0
Placebo		Week 4	80.0	72.0	8.0
Placebo		Week 6	88.0	72.0	16.0
Placebo		Week 6	100.0	72.0	28.0
Placebo		Week 6	93.0	72.0	21.0
Placebo		Week 8	64.0	72.0	-8.0
Placebo		Week 8	60.0	72.0	-12.0
Placebo		Week 8	72.0	72.0	0.0
Placebo			72.0	72.0
Placebo			72.0	72.0
Placebo			72.0	72.0
Placebo			66.0	72.0
Placebo			72.0	72.0
Placebo			66.0	72.0
Xanomeline High Dose		Week 12	84.0	80.0	4.0
Xanomeline High Dose		Week 12	88.0	94.0	-6.0
Xanomeline High Dose		Week 12	88.0	90.0	-2.0
Xanomeline High Dose		Week 2	82.0	80.0	2.0
Xanomeline High Dose		Week 2	94.0	94.0	0.0
Xanomeline High Dose		Week 2	88.0	90.0	-2.0
Xanomeline High Dose		Week 4	72.0	80.0	-8.0
Xanomeline High Dose		Week 4	70.0	94.0	-24.0
Xanomeline High Dose		Week 4	70.0	90.0	-20.0
Xanomeline High Dose		Week 6	72.0	80.0	-8.0
Xanomeline High Dose		Week 6	76.0	94.0	-18.0
Xanomeline High Dose		Week 6	76.0	90.0	-14.0
Xanomeline High Dose		Week 8	78.0	80.0	-2.0
Xanomeline High Dose		Week 8	90.0	94.0	-4.0
Xanomeline High Dose		Week 8	84.0	90.0	-6.0
Xanomeline High Dose			69.0	80.0
Xanomeline High Dose			72.0	94.0
Xanomeline High Dose			76.0	90.0
Xanomeline High Dose			76.0	80.0
Xanomeline High Dose			90.0	94.0
Xanomeline High Dose			88.0	90.0
Xanomeline Low Dose		Week 12	64.0	72.0	-8.0
Xanomeline Low Dose		Week 12	78.0	72.0	6.0
Xanomeline Low Dose		Week 12	62.0	82.0	-20.0
Xanomeline Low Dose		Week 16	62.0	72.0	-10.0
Xanomeline Low Dose		Week 16	76.0	72.0	4.0
Xanomeline Low Dose		Week 16	74.0	82.0	-8.0
Xanomeline Low Dose		Week 2	86.0	72.0	14.0
Xanomeline Low Dose		Week 2	82.0	72.0	10.0
Xanomeline Low Dose		Week 2	84.0	82.0	2.0
Xanomeline Low Dose		Week 20	72.0	72.0	0.0
Xanomeline Low Dose		Week 20	76.0	72.0	4.0
Xanomeline Low Dose		Week 20	76.0	82.0	-6.0
Xanomeline Low Dose		Week 24	66.0	72.0	-6.0
Xanomeline Low Dose		Week 24	80.0	72.0	8.0
Xanomeline Low Dose		Week 24	72.0	82.0	-10.0
Xanomeline Low Dose		Week 26	68.0	72.0	-4.0
Xanomeline Low Dose		Week 26	88.0	72.0	16.0
Xanomeline Low Dose		Week 26	80.0	82.0	-2.0
Xanomeline Low Dose		Week 4	64.0	72.0	-8.0
Xanomeline Low Dose		Week 4	72.0	72.0	0.0
Xanomeline Low Dose		Week 4	71.0	82.0	-11.0
Xanomeline Low Dose		Week 6	78.0	72.0	6.0
Xanomeline Low Dose		Week 6	76.0	72.0	4.0
Xanomeline Low Dose		Week 6	78.0	82.0	-4.0
Xanomeline Low Dose		Week 8	72.0	72.0	0.0
Xanomeline Low Dose		Week 8	78.0	72.0	6.0
Xanomeline Low Dose		Week 8	72.0	82.0	-10.0
Xanomeline Low Dose			84.0	72.0
Xanomeline Low Dose			100.0	72.0
Xanomeline Low Dose			96.0	82.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose			96.0	72.0
Xanomeline Low Dose			100.0	82.0
Xanomeline Low Dose		Week 2	72.0	85.0	-13.0
Xanomeline Low Dose		Week 2	76.0	90.0	-14.0
Xanomeline Low Dose		Week 2	76.0	88.0	-12.0
Xanomeline Low Dose		Week 4	82.0	85.0	-3.0
Xanomeline Low Dose		Week 4	90.0	90.0	0.0
Xanomeline Low Dose		Week 4	90.0	88.0	2.0
Xanomeline Low Dose		Week 6	82.0	85.0	-3.0
Xanomeline Low Dose		Week 6	88.0	90.0	-2.0
Xanomeline Low Dose		Week 6	84.0	88.0	-4.0
Xanomeline Low Dose			72.0	85.0
Xanomeline Low Dose			80.0	90.0
Xanomeline Low Dose			72.0	88.0
Placebo		Week 12	60.0	66.0	-6.0
Placebo		Week 12	60.0	72.0	-12.0
Placebo		Week 12	60.0	72.0	-12.0
Placebo		Week 16	64.0	66.0	-2.0
Placebo		Week 16	68.0	72.0	-4.0
Placebo		Week 16	64.0	72.0	-8.0
Placebo		Week 2	60.0	66.0	-6.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 2	64.0	72.0	-8.0
Placebo		Week 20	55.0	66.0	-11.0
Placebo		Week 20	64.0	72.0	-8.0
Placebo		Week 20	62.0	72.0	-10.0
Placebo		Week 4	64.0	66.0	-2.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	64.0	72.0	-8.0
Placebo		Week 6	60.0	66.0	-6.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 8	60.0	66.0	-6.0
Placebo		Week 8	64.0	72.0	-8.0
Placebo		Week 8	68.0	72.0	-4.0
Placebo			60.0	66.0
Placebo			62.0	72.0
Placebo			64.0	72.0
Xanomeline High Dose		Week 12	80.0	78.0	2.0
Xanomeline High Dose		Week 12	84.0	80.0	4.0
Xanomeline High Dose		Week 12	84.0	78.0	6.0
Xanomeline High Dose		Week 16	84.0	78.0	6.0
Xanomeline High Dose		Week 16	96.0	80.0	16.0
Xanomeline High Dose		Week 16	92.0	78.0	14.0
Xanomeline High Dose		Week 2	82.0	78.0	4.0
Xanomeline High Dose		Week 2	88.0	80.0	8.0
Xanomeline High Dose		Week 2	90.0	78.0	12.0
Xanomeline High Dose		Week 20	96.0	78.0	18.0
Xanomeline High Dose		Week 20	92.0	80.0	12.0
Xanomeline High Dose		Week 20	92.0	78.0	14.0
Xanomeline High Dose		Week 24	80.0	78.0	2.0
Xanomeline High Dose		Week 24	92.0	80.0	12.0
Xanomeline High Dose		Week 24	92.0	78.0	14.0
Xanomeline High Dose		Week 26	80.0	78.0	2.0
Xanomeline High Dose		Week 26	84.0	80.0	4.0
Xanomeline High Dose		Week 26	88.0	78.0	10.0
Xanomeline High Dose		Week 4	94.0	78.0	16.0
Xanomeline High Dose		Week 4	102.0	80.0	22.0
Xanomeline High Dose		Week 4	114.0	78.0	36.0
Xanomeline High Dose		Week 6	84.0	78.0	6.0
Xanomeline High Dose		Week 6	76.0	80.0	-4.0
Xanomeline High Dose		Week 6	84.0	78.0	6.0
Xanomeline High Dose		Week 8	82.0	78.0	4.0
Xanomeline High Dose		Week 8	88.0	80.0	8.0
Xanomeline High Dose		Week 8	90.0	78.0	12.0
Xanomeline High Dose			66.0	78.0
Xanomeline High Dose			72.0	80.0
Xanomeline High Dose			72.0	78.0
Xanomeline High Dose			104.0	78.0
Xanomeline High Dose			108.0	80.0
Xanomeline High Dose			102.0	78.0
Xanomeline Low Dose		Week 2	72.0	88.0	-16.0
Xanomeline Low Dose		Week 2	78.0	100.0	-22.0
Xanomeline Low Dose		Week 2	78.0	104.0	-26.0
Xanomeline Low Dose		Week 4	70.0	88.0	-18.0
Xanomeline Low Dose		Week 4	78.0	100.0	-22.0
Xanomeline Low Dose		Week 4	76.0	104.0	-28.0
Xanomeline Low Dose			72.0	88.0
Xanomeline Low Dose			84.0	100.0
Xanomeline Low Dose			72.0	104.0
Xanomeline Low Dose			72.0	88.0
Xanomeline Low Dose			76.0	100.0
Xanomeline Low Dose			88.0	104.0
Placebo		Week 12	72.0	69.0	3.0
Placebo		Week 12	87.0	84.0	3.0
Placebo		Week 12	78.0	78.0	0.0
Placebo		Week 16	72.0	69.0	3.0
Placebo		Week 16	78.0	84.0	-6.0
Placebo		Week 16	75.0	78.0	-3.0
Placebo		Week 2	64.0	69.0	-5.0
Placebo		Week 2	70.0	84.0	-14.0
Placebo		Week 2	78.0	78.0	0.0
Placebo		Week 20	72.0	69.0	3.0
Placebo		Week 20	78.0	84.0	-6.0
Placebo		Week 20	75.0	78.0	-3.0
Placebo		Week 24	63.0	69.0	-6.0
Placebo		Week 24	75.0	84.0	-9.0
Placebo		Week 24	75.0	78.0	-3.0
Placebo		Week 26	60.0	69.0	-9.0
Placebo		Week 26	75.0	84.0	-9.0
Placebo		Week 26	75.0	78.0	-3.0
Placebo		Week 4	66.0	69.0	-3.0
Placebo		Week 4	90.0	84.0	6.0
Placebo		Week 4	75.0	78.0	-3.0
Placebo		Week 6	78.0	69.0	9.0
Placebo		Week 6	96.0	84.0	12.0
Placebo		Week 6	87.0	78.0	9.0
Placebo		Week 8	66.0	69.0	-3.0
Placebo		Week 8	90.0	84.0	6.0
Placebo		Week 8	75.0	78.0	-3.0
Placebo			60.0	69.0
Placebo			75.0	84.0
Placebo			66.0	78.0
Placebo			60.0	69.0
Placebo			78.0	84.0
Placebo			78.0	78.0
Xanomeline Low Dose		Week 2	75.0	63.0	12.0
Xanomeline Low Dose		Week 2	99.0	75.0	24.0
Xanomeline Low Dose		Week 2	75.0	75.0	0.0
Xanomeline Low Dose			78.0	63.0
Xanomeline Low Dose			87.0	75.0
Xanomeline Low Dose			87.0	75.0
Xanomeline Low Dose		Week 12	75.0	60.0	15.0
Xanomeline Low Dose		Week 12	81.0	60.0	21.0
Xanomeline Low Dose		Week 12	75.0	66.0	9.0
Xanomeline Low Dose		Week 16	54.0	60.0	-6.0
Xanomeline Low Dose		Week 16	57.0	60.0	-3.0
Xanomeline Low Dose		Week 16	60.0	66.0	-6.0
Xanomeline Low Dose		Week 2	72.0	60.0	12.0
Xanomeline Low Dose		Week 2	75.0	60.0	15.0
Xanomeline Low Dose		Week 2	81.0	66.0	15.0
Xanomeline Low Dose		Week 20	58.0	60.0	-2.0
Xanomeline Low Dose		Week 20	62.0	60.0	2.0
Xanomeline Low Dose		Week 20	60.0	66.0	-6.0
Xanomeline Low Dose		Week 24	69.0	60.0	9.0
Xanomeline Low Dose		Week 24	63.0	60.0	3.0
Xanomeline Low Dose		Week 24	60.0	66.0	-6.0
Xanomeline Low Dose		Week 26	66.0	60.0	6.0
Xanomeline Low Dose		Week 26	84.0	60.0	24.0
Xanomeline Low Dose		Week 26	75.0	66.0	9.0
Xanomeline Low Dose		Week 4	69.0	60.0	9.0
Xanomeline Low Dose		Week 4	78.0	60.0	18.0
Xanomeline Low Dose		Week 4	78.0	66.0	12.0
Xanomeline Low Dose		Week 6	72.0	60.0	12.0
Xanomeline Low Dose		Week 6	69.0	60.0	9.0
Xanomeline Low Dose		Week 6	66.0	66.0	0.0
Xanomeline Low Dose		Week 8	66.0	60.0	6.0
Xanomeline Low Dose		Week 8	72.0	60.0	12.0
Xanomeline Low Dose		Week 8	72.0	66.0	6.0
Xanomeline High Dose		Week 12	56.0	58.0	-2.0
Xanomeline High Dose		Week 12	74.0	62.0	12.0
Xanomeline High Dose		Week 12	68.0	52.0	16.0
Xanomeline High Dose		Week 16	72.0	58.0	14.0
Xanomeline High Dose		Week 16	78.0	62.0	16.0
Xanomeline High Dose		Week 16	78.0	52.0	26.0
Xanomeline High Dose		Week 2	68.0	58.0	10.0
Xanomeline High Dose		Week 2	82.0	62.0	20.0
Xanomeline High Dose		Week 2	80.0	52.0	28.0
Xanomeline High Dose		Week 20	78.0	58.0	20.0
Xanomeline High Dose		Week 20	80.0	62.0	18.0
Xanomeline High Dose		Week 20	82.0	52.0	30.0
Xanomeline High Dose		Week 24	54.0	58.0	-4.0
Xanomeline High Dose		Week 24	54.0	62.0	-8.0
Xanomeline High Dose		Week 24	54.0	52.0	2.0
Xanomeline High Dose		Week 26	54.0	58.0	-4.0
Xanomeline High Dose		Week 26	56.0	62.0	-6.0
Xanomeline High Dose		Week 26	56.0	52.0	4.0
Xanomeline High Dose		Week 4	66.0	58.0	8.0
Xanomeline High Dose		Week 4	72.0	62.0	10.0
Xanomeline High Dose		Week 4	74.0	52.0	22.0
Xanomeline High Dose		Week 6	64.0	58.0	6.0
Xanomeline High Dose		Week 6	66.0	62.0	4.0
Xanomeline High Dose		Week 6	64.0	52.0	12.0
Xanomeline High Dose		Week 8	78.0	58.0	20.0
Xanomeline High Dose		Week 8	84.0	62.0	22.0
Xanomeline High Dose		Week 8	78.0	52.0	26.0
Xanomeline High Dose			76.0	58.0
Xanomeline High Dose			76.0	62.0
Xanomeline High Dose			78.0	52.0
Xanomeline High Dose			60.0	58.0
Xanomeline High Dose			58.0	62.0
Xanomeline High Dose			58.0	52.0
Xanomeline Low Dose		Week 12	60.0	68.0	-8.0
Xanomeline Low Dose		Week 12	82.0	66.0	16.0
Xanomeline Low Dose		Week 12	76.0	66.0	10.0
Xanomeline Low Dose		Week 2	78.0	68.0	10.0
Xanomeline Low Dose		Week 2	82.0	66.0	16.0
Xanomeline Low Dose		Week 2	84.0	66.0	18.0
Xanomeline Low Dose		Week 4	56.0	68.0	-12.0
Xanomeline Low Dose		Week 4	76.0	66.0	10.0
Xanomeline Low Dose		Week 4	90.0	66.0	24.0
Xanomeline Low Dose		Week 6	78.0	68.0	10.0
Xanomeline Low Dose		Week 6	90.0	66.0	24.0
Xanomeline Low Dose		Week 6	84.0	66.0	18.0
Xanomeline Low Dose		Week 8	88.0	68.0	20.0
Xanomeline Low Dose		Week 8	90.0	66.0	24.0
Xanomeline Low Dose		Week 8	90.0	66.0	24.0
Xanomeline Low Dose			78.0	68.0
Xanomeline Low Dose			72.0	66.0
Xanomeline Low Dose			90.0	66.0
Xanomeline Low Dose			88.0	68.0
Xanomeline Low Dose			90.0	66.0
Xanomeline Low Dose			86.0	66.0
Placebo		Week 12	63.0	78.0	-15.0
Placebo		Week 12	72.0	63.0	9.0
Placebo		Week 12	72.0	60.0	12.0
Placebo		Week 16	60.0	78.0	-18.0
Placebo		Week 16	72.0	63.0	9.0
Placebo		Week 16	69.0	60.0	9.0
Placebo		Week 2	57.0	78.0	-21.0
Placebo		Week 2	66.0	63.0	3.0
Placebo		Week 2	69.0	60.0	9.0
Placebo		Week 20	63.0	78.0	-15.0
Placebo		Week 20	69.0	63.0	6.0
Placebo		Week 20	72.0	60.0	12.0
Placebo		Week 24	63.0	78.0	-15.0
Placebo		Week 24	72.0	63.0	9.0
Placebo		Week 24	66.0	60.0	6.0
Placebo		Week 26	63.0	78.0	-15.0
Placebo		Week 26	69.0	63.0	6.0
Placebo		Week 26	72.0	60.0	12.0
Placebo		Week 4	60.0	78.0	-18.0
Placebo		Week 4	66.0	63.0	3.0
Placebo		Week 4	66.0	60.0	6.0
Placebo		Week 6	66.0	78.0	-12.0
Placebo		Week 6	69.0	63.0	6.0
Placebo		Week 6	72.0	60.0	12.0
Placebo		Week 8	75.0	78.0	-3.0
Placebo		Week 8	72.0	63.0	9.0
Placebo		Week 8	75.0	60.0	15.0
Placebo			66.0	78.0
Placebo			72.0	63.0
Placebo			75.0	60.0
Placebo			60.0	78.0
Placebo			63.0	63.0
Placebo			69.0	60.0
Xanomeline High Dose		Week 12	84.0	63.0	21.0
Xanomeline High Dose		Week 12	87.0	78.0	9.0
Xanomeline High Dose		Week 12	81.0	72.0	9.0
Xanomeline High Dose		Week 16	78.0	63.0	15.0
Xanomeline High Dose		Week 16	84.0	78.0	6.0
Xanomeline High Dose		Week 16	81.0	72.0	9.0
Xanomeline High Dose		Week 2	78.0	63.0	15.0
Xanomeline High Dose		Week 2	78.0	78.0	0.0
Xanomeline High Dose		Week 2	75.0	72.0	3.0
Xanomeline High Dose		Week 20	75.0	63.0	12.0
Xanomeline High Dose		Week 20	81.0	78.0	3.0
Xanomeline High Dose		Week 20	81.0	72.0	9.0
Xanomeline High Dose		Week 24	63.0	63.0	0.0
Xanomeline High Dose		Week 24	66.0	78.0	-12.0
Xanomeline High Dose		Week 24	69.0	72.0	-3.0
Xanomeline High Dose		Week 26	69.0	63.0	6.0
Xanomeline High Dose		Week 26	75.0	78.0	-3.0
Xanomeline High Dose		Week 26	72.0	72.0	0.0
Xanomeline High Dose		Week 4	69.0	63.0	6.0
Xanomeline High Dose		Week 4	87.0	78.0	9.0
Xanomeline High Dose		Week 4	78.0	72.0	6.0
Xanomeline High Dose		Week 6	69.0	63.0	6.0
Xanomeline High Dose		Week 6	78.0	78.0	0.0
Xanomeline High Dose		Week 6	78.0	72.0	6.0
Xanomeline High Dose		Week 8	75.0	63.0	12.0
Xanomeline High Dose		Week 8	75.0	78.0	-3.0
Xanomeline High Dose		Week 8	78.0	72.0	6.0
Xanomeline High Dose			84.0	63.0
Xanomeline High Dose			90.0	78.0
Xanomeline High Dose			90.0	72.0
Xanomeline High Dose			69.0	63.0
Xanomeline High Dose			75.0	78.0
Xanomeline High Dose			78.0	72.0
Xanomeline Low Dose		Week 2	69.0	75.0	-6.0
Xanomeline Low Dose		Week 2	60.0	78.0	-18.0
Xanomeline Low Dose		Week 2	75.0	87.0	-12.0
Xanomeline Low Dose		Week 4	72.0	75.0	-3.0
Xanomeline Low Dose		Week 4	66.0	78.0	-12.0
Xanomeline Low Dose		Week 4	63.0	87.0	-24.0
Xanomeline Low Dose		Week 6	75.0	75.0	0.0
Xanomeline Low Dose		Week 6	78.0	78.0	0.0
Xanomeline Low Dose		Week 6	69.0	87.0	-18.0
Xanomeline Low Dose		Week 8	75.0	75.0	0.0
Xanomeline Low Dose		Week 8	81.0	78.0	3.0
Xanomeline Low Dose		Week 8	68.0	87.0	-19.0
Xanomeline Low Dose			75.0	75.0
Xanomeline Low Dose			81.0	78.0
Xanomeline Low Dose			81.0	87.0
Xanomeline Low Dose			82.0	75.0
Xanomeline Low Dose			94.0	78.0
Xanomeline Low Dose			80.0	87.0
Xanomeline High Dose		Week 2	73.0	64.0	9.0
Xanomeline High Dose		Week 2	76.0	74.0	2.0
Xanomeline High Dose		Week 2	82.0	70.0	12.0
Xanomeline High Dose		Week 4	60.0	64.0	-4.0
Xanomeline High Dose		Week 4	92.0	74.0	18.0
Xanomeline High Dose		Week 4	76.0	70.0	6.0
Xanomeline High Dose		Week 6	70.0	64.0	6.0
Xanomeline High Dose		Week 6	80.0	74.0	6.0
Xanomeline High Dose		Week 6	82.0	70.0	12.0
Xanomeline High Dose			82.0	64.0
Xanomeline High Dose			92.0	74.0
Xanomeline High Dose			82.0	70.0
Xanomeline Low Dose		Week 12	72.0	54.0	18.0
Xanomeline Low Dose		Week 12	78.0	60.0	18.0
Xanomeline Low Dose		Week 12	81.0	60.0	21.0
Xanomeline Low Dose		Week 2	54.0	54.0	0.0
Xanomeline Low Dose		Week 2	69.0	60.0	9.0
Xanomeline Low Dose		Week 2	72.0	60.0	12.0
Xanomeline Low Dose		Week 4	57.0	54.0	3.0
Xanomeline Low Dose		Week 4	66.0	60.0	6.0
Xanomeline Low Dose		Week 4	60.0	60.0	0.0
Xanomeline Low Dose		Week 6	60.0	54.0	6.0
Xanomeline Low Dose		Week 6	66.0	60.0	6.0
Xanomeline Low Dose		Week 6	63.0	60.0	3.0
Xanomeline Low Dose		Week 8	51.0	54.0	-3.0
Xanomeline Low Dose		Week 8	57.0	60.0	-3.0
Xanomeline Low Dose		Week 8	54.0	60.0	-6.0
Xanomeline Low Dose			57.0	54.0
Xanomeline Low Dose			66.0	60.0
Xanomeline Low Dose			60.0	60.0
Xanomeline Low Dose			60.0	54.0
Xanomeline Low Dose			63.0	60.0
Xanomeline Low Dose			57.0	60.0
Xanomeline High Dose		Week 2	96.0	78.0	18.0
Xanomeline High Dose		Week 2	102.0	92.0	10.0
Xanomeline High Dose		Week 2	100.0	90.0	10.0
Xanomeline High Dose		Week 4	90.0	78.0	12.0
Xanomeline High Dose		Week 4	98.0	92.0	6.0
Xanomeline High Dose		Week 4	94.0	90.0	4.0
Xanomeline High Dose		Week 6	80.0	78.0	2.0
Xanomeline High Dose		Week 6	82.0	92.0	-10.0
Xanomeline High Dose		Week 6	82.0	90.0	-8.0
Xanomeline High Dose		Week 8	87.0	78.0	9.0
Xanomeline High Dose		Week 8	94.0	92.0	2.0
Xanomeline High Dose		Week 8	88.0	90.0	-2.0
Xanomeline High Dose			86.0	78.0
Xanomeline High Dose			98.0	92.0
Xanomeline High Dose			98.0	90.0
Placebo		Week 12	60.0	60.0	0.0
Placebo		Week 12	90.0	69.0	21.0
Placebo		Week 12	75.0	60.0	15.0
Placebo		Week 16	57.0	60.0	-3.0
Placebo		Week 16	69.0	69.0	0.0
Placebo		Week 16	60.0	60.0	0.0
Placebo		Week 2	51.0	60.0	-9.0
Placebo		Week 2	60.0	69.0	-9.0
Placebo		Week 2	57.0	60.0	-3.0
Placebo		Week 20	54.0	60.0	-6.0
Placebo		Week 20	63.0	69.0	-6.0
Placebo		Week 20	60.0	60.0	0.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 4	64.0	69.0	-5.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 6	56.0	60.0	-4.0
Placebo		Week 6	70.0	69.0	1.0
Placebo		Week 6	66.0	60.0	6.0
Placebo		Week 8	60.0	60.0	0.0
Placebo		Week 8	69.0	69.0	0.0
Placebo		Week 8	60.0	60.0	0.0
Placebo			57.0	60.0
Placebo			66.0	69.0
Placebo			63.0	60.0
Placebo			60.0	60.0
Placebo			66.0	69.0
Placebo			57.0	60.0
Xanomeline Low Dose		Week 2	60.0	57.0	3.0
Xanomeline Low Dose		Week 2	72.0	60.0	12.0
Xanomeline Low Dose		Week 2	69.0	60.0	9.0
Xanomeline Low Dose		Week 4	66.0	57.0	9.0
Xanomeline Low Dose		Week 4	75.0	60.0	15.0
Xanomeline Low Dose		Week 4	69.0	60.0	9.0
Xanomeline Low Dose		Week 6	60.0	57.0	3.0
Xanomeline Low Dose		Week 6	57.0	60.0	-3.0
Xanomeline Low Dose		Week 6	57.0	60.0	-3.0
Xanomeline Low Dose		Week 8	64.0	57.0	7.0
Xanomeline Low Dose		Week 8	60.0	60.0	0.0
Xanomeline Low Dose		Week 8	60.0	60.0	0.0
Xanomeline Low Dose			54.0	57.0
Xanomeline Low Dose			69.0	60.0
Xanomeline Low Dose			63.0	60.0
Xanomeline Low Dose			62.0	57.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			66.0	60.0
Placebo		Week 12	90.0	100.0	-10.0
Placebo		Week 12	100.0	112.0	-12.0
Placebo		Week 12	88.0	110.0	-22.0
Placebo		Week 16	87.0	100.0	-13.0
Placebo		Week 16	87.0	112.0	-25.0
Placebo		Week 16	90.0	110.0	-20.0
Placebo		Week 2	70.0	100.0	-30.0
Placebo		Week 2	92.0	112.0	-20.0
Placebo		Week 2	78.0	110.0	-32.0
Placebo		Week 20	88.0	100.0	-12.0
Placebo		Week 20	80.0	112.0	-32.0
Placebo		Week 20	82.0	110.0	-28.0
Placebo		Week 24	76.0	100.0	-24.0
Placebo		Week 24	82.0	112.0	-30.0
Placebo		Week 24	80.0	110.0	-30.0
Placebo		Week 26	92.0	100.0	-8.0
Placebo		Week 26	90.0	112.0	-22.0
Placebo		Week 26	86.0	110.0	-24.0
Placebo		Week 4	92.0	100.0	-8.0
Placebo		Week 4	94.0	112.0	-18.0
Placebo		Week 4	92.0	110.0	-18.0
Placebo		Week 6	70.0	100.0	-30.0
Placebo		Week 6	97.0	112.0	-15.0
Placebo		Week 6	88.0	110.0	-22.0
Placebo		Week 8	90.0	100.0	-10.0
Placebo		Week 8	102.0	112.0	-10.0
Placebo		Week 8	102.0	110.0	-8.0
Placebo			81.0	100.0
Placebo			101.0	112.0
Placebo			93.0	110.0
Placebo			80.0	100.0
Placebo			86.0	112.0
Placebo			96.0	110.0
Placebo		Week 12	75.0	84.0	-9.0
Placebo		Week 12	94.0	100.0	-6.0
Placebo		Week 12	90.0	100.0	-10.0
Placebo		Week 16	84.0	84.0	0.0
Placebo		Week 16	90.0	100.0	-10.0
Placebo		Week 16	84.0	100.0	-16.0
Placebo		Week 2	75.0	84.0	-9.0
Placebo		Week 2	90.0	100.0	-10.0
Placebo		Week 2	96.0	100.0	-4.0
Placebo		Week 4	72.0	84.0	-12.0
Placebo		Week 4	81.0	100.0	-19.0
Placebo		Week 4	78.0	100.0	-22.0
Placebo		Week 6	90.0	84.0	6.0
Placebo		Week 6	72.0	100.0	-28.0
Placebo		Week 6	96.0	100.0	-4.0
Placebo		Week 8	75.0	84.0	-9.0
Placebo		Week 8	87.0	100.0	-13.0
Placebo		Week 8	75.0	100.0	-25.0
Placebo			78.0	84.0
Placebo			90.0	100.0
Placebo			84.0	100.0
Placebo			81.0	84.0
Placebo			96.0	100.0
Placebo			93.0	100.0
Xanomeline High Dose		Week 12	75.0	72.0	3.0
Xanomeline High Dose		Week 12	87.0	75.0	12.0
Xanomeline High Dose		Week 12	81.0	81.0	0.0
Xanomeline High Dose		Week 16	51.0	72.0	-21.0
Xanomeline High Dose		Week 16	60.0	75.0	-15.0
Xanomeline High Dose		Week 16	69.0	81.0	-12.0
Xanomeline High Dose		Week 2	60.0	72.0	-12.0
Xanomeline High Dose		Week 2	84.0	75.0	9.0
Xanomeline High Dose		Week 2	81.0	81.0	0.0
Xanomeline High Dose		Week 20	60.0	72.0	-12.0
Xanomeline High Dose		Week 20	75.0	75.0	0.0
Xanomeline High Dose		Week 20	78.0	81.0	-3.0
Xanomeline High Dose		Week 24	66.0	72.0	-6.0
Xanomeline High Dose		Week 24	81.0	75.0	6.0
Xanomeline High Dose		Week 24	75.0	81.0	-6.0
Xanomeline High Dose		Week 26	66.0	72.0	-6.0
Xanomeline High Dose		Week 26	72.0	75.0	-3.0
Xanomeline High Dose		Week 26	87.0	81.0	6.0
Xanomeline High Dose		Week 4	75.0	72.0	3.0
Xanomeline High Dose		Week 4	87.0	75.0	12.0
Xanomeline High Dose		Week 4	90.0	81.0	9.0
Xanomeline High Dose		Week 6	75.0	72.0	3.0
Xanomeline High Dose		Week 6	93.0	75.0	18.0
Xanomeline High Dose		Week 6	90.0	81.0	9.0
Xanomeline High Dose		Week 8	60.0	72.0	-12.0
Xanomeline High Dose		Week 8	72.0	75.0	-3.0
Xanomeline High Dose		Week 8	69.0	81.0	-12.0
Xanomeline High Dose			60.0	72.0
Xanomeline High Dose			75.0	75.0
Xanomeline High Dose			72.0	81.0
Xanomeline High Dose			63.0	72.0
Xanomeline High Dose			72.0	75.0
Xanomeline High Dose			75.0	81.0
Placebo		Week 12	54.0	66.0	-12.0
Placebo		Week 12	63.0	66.0	-3.0
Placebo		Week 12	57.0	69.0	-12.0
Placebo		Week 16	51.0	66.0	-15.0
Placebo		Week 16	60.0	66.0	-6.0
Placebo		Week 16	60.0	69.0	-9.0
Placebo		Week 2	60.0	66.0	-6.0
Placebo		Week 2	69.0	66.0	3.0
Placebo		Week 2	63.0	69.0	-6.0
Placebo		Week 20	60.0	66.0	-6.0
Placebo		Week 20	54.0	66.0	-12.0
Placebo		Week 20	60.0	69.0	-9.0
Placebo		Week 24	63.0	66.0	-3.0
Placebo		Week 24	75.0	66.0	9.0
Placebo		Week 24	60.0	69.0	-9.0
Placebo		Week 26	60.0	66.0	-6.0
Placebo		Week 26	69.0	66.0	3.0
Placebo		Week 26	63.0	69.0	-6.0
Placebo		Week 4	66.0	66.0	0.0
Placebo		Week 4	81.0	66.0	15.0
Placebo		Week 4	78.0	69.0	9.0
Placebo		Week 6	60.0	66.0	-6.0
Placebo		Week 6	69.0	66.0	3.0
Placebo		Week 6	63.0	69.0	-6.0
Placebo		Week 8	63.0	66.0	-3.0
Placebo		Week 8	72.0	66.0	6.0
Placebo		Week 8	72.0	69.0	3.0
Placebo			63.0	66.0
Placebo			66.0	66.0
Placebo			72.0	69.0
Xanomeline Low Dose		Week 12	72.0	81.0	-9.0
Xanomeline Low Dose		Week 12	78.0	81.0	-3.0
Xanomeline Low Dose		Week 12	87.0	78.0	9.0
Xanomeline Low Dose		Week 16	75.0	81.0	-6.0
Xanomeline Low Dose		Week 16	84.0	81.0	3.0
Xanomeline Low Dose		Week 16	78.0	78.0	0.0
Xanomeline Low Dose		Week 2	81.0	81.0	0.0
Xanomeline Low Dose		Week 2	87.0	81.0	6.0
Xanomeline Low Dose		Week 2	93.0	78.0	15.0
Xanomeline Low Dose		Week 20	66.0	81.0	-15.0
Xanomeline Low Dose		Week 20	75.0	81.0	-6.0
Xanomeline Low Dose		Week 20	72.0	78.0	-6.0
Xanomeline Low Dose		Week 24	90.0	81.0	9.0
Xanomeline Low Dose		Week 24	81.0	81.0	0.0
Xanomeline Low Dose		Week 24	72.0	78.0	-6.0
Xanomeline Low Dose		Week 26	72.0	81.0	-9.0
Xanomeline Low Dose		Week 26	75.0	81.0	-6.0
Xanomeline Low Dose		Week 26	72.0	78.0	-6.0
Xanomeline Low Dose		Week 4	78.0	81.0	-3.0
Xanomeline Low Dose		Week 4	81.0	81.0	0.0
Xanomeline Low Dose		Week 4	81.0	78.0	3.0
Xanomeline Low Dose		Week 6	75.0	81.0	-6.0
Xanomeline Low Dose		Week 6	66.0	81.0	-15.0
Xanomeline Low Dose		Week 6	72.0	78.0	-6.0
Xanomeline Low Dose		Week 8	72.0	81.0	-9.0
Xanomeline Low Dose		Week 8	87.0	81.0	6.0
Xanomeline Low Dose		Week 8	90.0	78.0	12.0
Xanomeline Low Dose			87.0	81.0
Xanomeline Low Dose			93.0	81.0
Xanomeline Low Dose			99.0	78.0
Xanomeline Low Dose			69.0	81.0
Xanomeline Low Dose			87.0	81.0
Xanomeline Low Dose			78.0	78.0
Placebo		Week 12	72.0	60.0	12.0
Placebo		Week 12	70.0	64.0	6.0
Placebo		Week 12	84.0	64.0	20.0
Placebo		Week 16	64.0	60.0	4.0
Placebo		Week 16	66.0	64.0	2.0
Placebo		Week 16	64.0	64.0	0.0
Placebo		Week 2	64.0	60.0	4.0
Placebo		Week 2	70.0	64.0	6.0
Placebo		Week 2	72.0	64.0	8.0
Placebo		Week 20	65.0	60.0	5.0
Placebo		Week 20	74.0	64.0	10.0
Placebo		Week 20	66.0	64.0	2.0
Placebo		Week 24	66.0	60.0	6.0
Placebo		Week 24	76.0	64.0	12.0
Placebo		Week 24	72.0	64.0	8.0
Placebo		Week 26	64.0	60.0	4.0
Placebo		Week 26	84.0	64.0	20.0
Placebo		Week 26	76.0	64.0	12.0
Placebo		Week 4	62.0	60.0	2.0
Placebo		Week 4	78.0	64.0	14.0
Placebo		Week 4	68.0	64.0	4.0
Placebo		Week 6	62.0	60.0	2.0
Placebo		Week 6	70.0	64.0	6.0
Placebo		Week 6	70.0	64.0	6.0
Placebo		Week 8	70.0	60.0	10.0
Placebo		Week 8	66.0	64.0	2.0
Placebo		Week 8	66.0	64.0	2.0
Placebo			60.0	60.0
Placebo			74.0	64.0
Placebo			72.0	64.0
Placebo			72.0	60.0
Placebo			80.0	64.0
Placebo			76.0	64.0
Xanomeline Low Dose		Week 2	72.0	60.0	12.0
Xanomeline Low Dose		Week 2	72.0	60.0	12.0
Xanomeline Low Dose		Week 2	68.0	64.0	4.0
Xanomeline High Dose		Week 12	84.0	56.0	28.0
Xanomeline High Dose		Week 12	80.0	56.0	24.0
Xanomeline High Dose		Week 12	80.0	60.0	20.0
Xanomeline High Dose		Week 16	68.0	56.0	12.0
Xanomeline High Dose		Week 16	72.0	56.0	16.0
Xanomeline High Dose		Week 16	68.0	60.0	8.0
Xanomeline High Dose		Week 2	76.0	56.0	20.0
Xanomeline High Dose		Week 2	72.0	56.0	16.0
Xanomeline High Dose		Week 2	72.0	60.0	12.0
Xanomeline High Dose		Week 20	52.0	56.0	-4.0
Xanomeline High Dose		Week 20	56.0	56.0	0.0
Xanomeline High Dose		Week 20	56.0	60.0	-4.0
Xanomeline High Dose		Week 24	64.0	56.0	8.0
Xanomeline High Dose		Week 24	64.0	56.0	8.0
Xanomeline High Dose		Week 24	60.0	60.0	0.0
Xanomeline High Dose		Week 4	80.0	56.0	24.0
Xanomeline High Dose		Week 4	76.0	56.0	20.0
Xanomeline High Dose		Week 4	76.0	60.0	16.0
Xanomeline High Dose		Week 6	84.0	56.0	28.0
Xanomeline High Dose		Week 6	80.0	56.0	24.0
Xanomeline High Dose		Week 6	80.0	60.0	20.0
Xanomeline High Dose		Week 8	68.0	56.0	12.0
Xanomeline High Dose		Week 8	64.0	56.0	8.0
Xanomeline High Dose		Week 8	64.0	60.0	4.0
Xanomeline High Dose			84.0	56.0
Xanomeline High Dose			80.0	56.0
Xanomeline High Dose			80.0	60.0
Xanomeline High Dose			68.0	56.0
Xanomeline High Dose			72.0	56.0
Xanomeline High Dose			68.0	60.0
Xanomeline High Dose		Week 2	72.0	76.0	-4.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 4	64.0	76.0	-12.0
Xanomeline High Dose		Week 4	64.0	72.0	-8.0
Xanomeline High Dose		Week 4	64.0	72.0	-8.0
Xanomeline High Dose			72.0	76.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			72.0	72.0
Xanomeline High Dose			68.0	76.0
Xanomeline High Dose			64.0	72.0
Xanomeline High Dose			64.0	72.0
Placebo		Week 12	86.0	88.0	-2.0
Placebo		Week 12	86.0	88.0	-2.0
Placebo		Week 12	84.0	84.0	0.0
Placebo		Week 16	84.0	88.0	-4.0
Placebo		Week 16	80.0	88.0	-8.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	80.0	88.0	-8.0
Placebo		Week 2	80.0	84.0	-4.0
Placebo		Week 20	76.0	88.0	-12.0
Placebo		Week 20	76.0	88.0	-12.0
Placebo		Week 20	72.0	84.0	-12.0
Placebo		Week 24	92.0	88.0	4.0
Placebo		Week 24	84.0	88.0	-4.0
Placebo		Week 24	88.0	84.0	4.0
Placebo		Week 26	80.0	88.0	-8.0
Placebo		Week 26	80.0	88.0	-8.0
Placebo		Week 26	76.0	84.0	-8.0
Placebo		Week 4	80.0	88.0	-8.0
Placebo		Week 4	80.0	88.0	-8.0
Placebo		Week 4	76.0	84.0	-8.0
Placebo		Week 6	80.0	88.0	-8.0
Placebo		Week 6	80.0	88.0	-8.0
Placebo		Week 6	76.0	84.0	-8.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo		Week 8	80.0	84.0	-4.0
Xanomeline Low Dose		Week 2	80.0	64.0	16.0
Xanomeline Low Dose		Week 2	80.0	60.0	20.0
Xanomeline Low Dose		Week 2	76.0	60.0	16.0
Xanomeline Low Dose		Week 4	88.0	64.0	24.0
Xanomeline Low Dose		Week 4	92.0	60.0	32.0
Xanomeline Low Dose		Week 4	88.0	60.0	28.0
Xanomeline Low Dose		Week 6	84.0	64.0	20.0
Xanomeline Low Dose		Week 6	80.0	60.0	20.0
Xanomeline Low Dose		Week 6	80.0	60.0	20.0
Xanomeline Low Dose		Week 8	84.0	64.0	20.0
Xanomeline Low Dose		Week 8	80.0	60.0	20.0
Xanomeline Low Dose		Week 8	80.0	60.0	20.0
Xanomeline Low Dose			84.0	64.0
Xanomeline Low Dose			80.0	60.0
Xanomeline Low Dose			80.0	60.0
Xanomeline Low Dose			84.0	64.0
Xanomeline Low Dose			80.0	60.0
Xanomeline Low Dose			80.0	60.0
Xanomeline Low Dose		Week 2	64.0	60.0	4.0
Xanomeline Low Dose		Week 2	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	60.0	56.0	4.0
Xanomeline Low Dose		Week 4	68.0	60.0	8.0
Xanomeline Low Dose		Week 4	64.0	60.0	4.0
Xanomeline Low Dose		Week 4	64.0	56.0	8.0
Xanomeline Low Dose		Week 6	68.0	60.0	8.0
Xanomeline Low Dose		Week 6	68.0	60.0	8.0
Xanomeline Low Dose		Week 6	64.0	56.0	8.0
Xanomeline Low Dose			80.0	60.0
Xanomeline Low Dose			76.0	60.0
Xanomeline Low Dose			76.0	56.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			60.0	56.0
Placebo		Week 12	56.0	68.0	-12.0
Placebo		Week 12	60.0	64.0	-4.0
Placebo		Week 12	60.0	64.0	-4.0
Placebo		Week 16	56.0	68.0	-12.0
Placebo		Week 16	60.0	64.0	-4.0
Placebo		Week 16	56.0	64.0	-8.0
Placebo		Week 2	52.0	68.0	-16.0
Placebo		Week 2	64.0	64.0	0.0
Placebo		Week 2	60.0	64.0	-4.0
Placebo		Week 20	64.0	68.0	-4.0
Placebo		Week 20	60.0	64.0	-4.0
Placebo		Week 20	60.0	64.0	-4.0
Placebo		Week 24	60.0	68.0	-8.0
Placebo		Week 24	60.0	64.0	-4.0
Placebo		Week 24	56.0	64.0	-8.0
Placebo		Week 26	64.0	68.0	-4.0
Placebo		Week 26	60.0	64.0	-4.0
Placebo		Week 26	60.0	64.0	-4.0
Placebo		Week 4	64.0	68.0	-4.0
Placebo		Week 4	60.0	64.0	-4.0
Placebo		Week 4	60.0	64.0	-4.0
Placebo		Week 6	64.0	68.0	-4.0
Placebo		Week 6	60.0	64.0	-4.0
Placebo		Week 6	60.0	64.0	-4.0
Placebo		Week 8	60.0	68.0	-8.0
Placebo		Week 8	58.0	64.0	-6.0
Placebo		Week 8	58.0	64.0	-6.0
Placebo			60.0	68.0
Placebo			60.0	64.0
Placebo			56.0	64.0
Placebo			60.0	68.0
Placebo			56.0	64.0
Placebo			56.0	64.0
Xanomeline High Dose		Week 12	80.0	76.0	4.0
Xanomeline High Dose		Week 12	76.0	76.0	0.0
Xanomeline High Dose		Week 12	76.0	72.0	4.0
Xanomeline High Dose		Week 16	68.0	76.0	-8.0
Xanomeline High Dose		Week 16	68.0	76.0	-8.0
Xanomeline High Dose		Week 16	72.0	72.0	0.0
Xanomeline High Dose		Week 2	76.0	76.0	0.0
Xanomeline High Dose		Week 2	76.0	76.0	0.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 4	72.0	76.0	-4.0
Xanomeline High Dose		Week 4	72.0	76.0	-4.0
Xanomeline High Dose		Week 4	68.0	72.0	-4.0
Xanomeline High Dose		Week 6	72.0	76.0	-4.0
Xanomeline High Dose		Week 6	76.0	76.0	0.0
Xanomeline High Dose		Week 6	74.0	72.0	2.0
Xanomeline High Dose		Week 8	80.0	76.0	4.0
Xanomeline High Dose		Week 8	76.0	76.0	0.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose			84.0	76.0
Xanomeline High Dose			88.0	76.0
Xanomeline High Dose			84.0	72.0
Placebo		Week 12	76.0	80.0	-4.0
Placebo		Week 12	72.0	76.0	-4.0
Placebo		Week 12	76.0	76.0	0.0
Placebo		Week 16	80.0	80.0	0.0
Placebo		Week 16	80.0	76.0	4.0
Placebo		Week 16	76.0	76.0	0.0
Placebo		Week 2	84.0	80.0	4.0
Placebo		Week 2	80.0	76.0	4.0
Placebo		Week 2	80.0	76.0	4.0
Placebo		Week 20	76.0	80.0	-4.0
Placebo		Week 20	76.0	76.0	0.0
Placebo		Week 20	80.0	76.0	4.0
Placebo		Week 24	72.0	80.0	-8.0
Placebo		Week 24	72.0	76.0	-4.0
Placebo		Week 24	76.0	76.0	0.0
Placebo		Week 26	76.0	80.0	-4.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 6	68.0	76.0	-8.0
Placebo		Week 8	76.0	80.0	-4.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo			88.0	80.0
Placebo			84.0	76.0
Placebo			84.0	76.0
Placebo		Week 12	64.0	76.0	-12.0
Placebo		Week 12	60.0	72.0	-12.0
Placebo		Week 12	60.0	76.0	-16.0
Placebo		Week 16	72.0	76.0	-4.0
Placebo		Week 16	72.0	72.0	0.0
Placebo		Week 16	68.0	76.0	-8.0
Placebo		Week 2	84.0	76.0	8.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	82.0	76.0	6.0
Placebo		Week 20	68.0	76.0	-8.0
Placebo		Week 20	64.0	72.0	-8.0
Placebo		Week 20	64.0	76.0	-12.0
Placebo		Week 24	80.0	76.0	4.0
Placebo		Week 24	82.0	72.0	10.0
Placebo		Week 24	84.0	76.0	8.0
Placebo		Week 26	80.0	76.0	4.0
Placebo		Week 26	80.0	72.0	8.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 4	72.0	76.0	-4.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 6	76.0	72.0	4.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	68.0	76.0	-8.0
Placebo			72.0	76.0
Placebo			68.0	72.0
Placebo			72.0	76.0
Placebo			80.0	76.0
Placebo			84.0	72.0
Placebo			84.0	76.0
Xanomeline High Dose		Week 2	76.0	64.0	12.0
Xanomeline High Dose		Week 2	76.0	60.0	16.0
Xanomeline High Dose		Week 2	72.0	64.0	8.0
Xanomeline High Dose		Week 4	76.0	64.0	12.0
Xanomeline High Dose		Week 4	82.0	60.0	22.0
Xanomeline High Dose		Week 4	80.0	64.0	16.0
Xanomeline High Dose		Week 6	68.0	64.0	4.0
Xanomeline High Dose		Week 6	64.0	60.0	4.0
Xanomeline High Dose		Week 6	64.0	64.0	0.0
Xanomeline High Dose			80.0	64.0
Xanomeline High Dose			76.0	60.0
Xanomeline High Dose			76.0	64.0
Xanomeline High Dose			68.0	64.0
Xanomeline High Dose			66.0	60.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose		Week 2	68.0	64.0	4.0
Xanomeline High Dose		Week 2	64.0	60.0	4.0
Xanomeline High Dose		Week 2	64.0	60.0	4.0
Xanomeline High Dose			84.0	64.0
Xanomeline High Dose			80.0	60.0
Xanomeline High Dose			80.0	60.0
Xanomeline Low Dose		Week 2	92.0	88.0	4.0
Xanomeline Low Dose		Week 2	88.0	84.0	4.0
Xanomeline Low Dose		Week 2	88.0	84.0	4.0
Xanomeline Low Dose		Week 4	88.0	88.0	0.0
Xanomeline Low Dose		Week 4	88.0	84.0	4.0
Xanomeline Low Dose		Week 4	84.0	84.0	0.0
Xanomeline Low Dose		Week 12	60.0	68.0	-8.0
Xanomeline Low Dose		Week 12	60.0	64.0	-4.0
Xanomeline Low Dose		Week 12	60.0	64.0	-4.0
Xanomeline Low Dose		Week 2	76.0	68.0	8.0
Xanomeline Low Dose		Week 2	76.0	64.0	12.0
Xanomeline Low Dose		Week 2	72.0	64.0	8.0
Xanomeline Low Dose		Week 4	64.0	68.0	-4.0
Xanomeline Low Dose		Week 4	60.0	64.0	-4.0
Xanomeline Low Dose		Week 4	60.0	64.0	-4.0
Xanomeline Low Dose		Week 6	64.0	68.0	-4.0
Xanomeline Low Dose		Week 6	60.0	64.0	-4.0
Xanomeline Low Dose		Week 6	60.0	64.0	-4.0
Xanomeline Low Dose		Week 8	60.0	68.0	-8.0
Xanomeline Low Dose		Week 8	60.0	64.0	-4.0
Xanomeline Low Dose		Week 8	56.0	64.0	-8.0
Xanomeline Low Dose			88.0	68.0
Xanomeline Low Dose			84.0	64.0
Xanomeline Low Dose			84.0	64.0
Xanomeline Low Dose			76.0	68.0
Xanomeline Low Dose			72.0	64.0
Xanomeline Low Dose			72.0	64.0
Placebo		Week 12	60.0	56.0	4.0
Placebo		Week 12	60.0	56.0	4.0
Placebo		Week 12	60.0	60.0	0.0
Placebo		Week 16	68.0	56.0	12.0
Placebo		Week 16	68.0	56.0	12.0
Placebo		Week 16	64.0	60.0	4.0
Placebo		Week 2	68.0	56.0	12.0
Placebo		Week 2	64.0	56.0	8.0
Placebo		Week 2	64.0	60.0	4.0
Placebo		Week 20	60.0	56.0	4.0
Placebo		Week 20	60.0	56.0	4.0
Placebo		Week 20	56.0	60.0	-4.0
Placebo		Week 24	68.0	56.0	12.0
Placebo		Week 24	64.0	56.0	8.0
Placebo		Week 24	64.0	60.0	4.0
Placebo		Week 26	56.0	56.0	0.0
Placebo		Week 26	52.0	56.0	-4.0
Placebo		Week 26	52.0	60.0	-8.0
Placebo		Week 4	52.0	56.0	-4.0
Placebo		Week 4	56.0	56.0	0.0
Placebo		Week 4	56.0	60.0	-4.0
Placebo		Week 6	60.0	56.0	4.0
Placebo		Week 6	60.0	56.0	4.0
Placebo		Week 6	56.0	60.0	-4.0
Placebo		Week 8	52.0	56.0	-4.0
Placebo		Week 8	52.0	56.0	-4.0
Placebo		Week 8	56.0	60.0	-4.0
Placebo			52.0	56.0
Placebo			52.0	56.0
Placebo			56.0	60.0
Placebo			60.0	56.0
Placebo			60.0	56.0
Placebo			64.0	60.0
Xanomeline High Dose		Week 12	80.0	92.0	-12.0
Xanomeline High Dose		Week 12	80.0	88.0	-8.0
Xanomeline High Dose		Week 12	76.0	88.0	-12.0
Xanomeline High Dose		Week 16	64.0	92.0	-28.0
Xanomeline High Dose		Week 16	60.0	88.0	-28.0
Xanomeline High Dose		Week 16	60.0	88.0	-28.0
Xanomeline High Dose		Week 2	96.0	92.0	4.0
Xanomeline High Dose		Week 2	96.0	88.0	8.0
Xanomeline High Dose		Week 2	92.0	88.0	4.0
Xanomeline High Dose		Week 20	64.0	92.0	-28.0
Xanomeline High Dose		Week 20	64.0	88.0	-24.0
Xanomeline High Dose		Week 20	60.0	88.0	-28.0
Xanomeline High Dose		Week 24	68.0	92.0	-24.0
Xanomeline High Dose		Week 24	64.0	88.0	-24.0
Xanomeline High Dose		Week 24	64.0	88.0	-24.0
Xanomeline High Dose		Week 26	76.0	92.0	-16.0
Xanomeline High Dose		Week 26	72.0	88.0	-16.0
Xanomeline High Dose		Week 26	72.0	88.0	-16.0
Xanomeline High Dose		Week 4	100.0	92.0	8.0
Xanomeline High Dose		Week 4	96.0	88.0	8.0
Xanomeline High Dose		Week 4	96.0	88.0	8.0
Xanomeline High Dose		Week 6	100.0	92.0	8.0
Xanomeline High Dose		Week 6	100.0	88.0	12.0
Xanomeline High Dose		Week 6	96.0	88.0	8.0
Xanomeline High Dose		Week 8	72.0	92.0	-20.0
Xanomeline High Dose		Week 8	68.0	88.0	-20.0
Xanomeline High Dose		Week 8	72.0	88.0	-16.0
Xanomeline High Dose			100.0	92.0
Xanomeline High Dose			96.0	88.0
Xanomeline High Dose			96.0	88.0
Xanomeline Low Dose		Week 12	88.0	88.0	0.0
Xanomeline Low Dose		Week 12	84.0	84.0	0.0
Xanomeline Low Dose		Week 12	84.0	84.0	0.0
Xanomeline Low Dose		Week 16	76.0	88.0	-12.0
Xanomeline Low Dose		Week 16	80.0	84.0	-4.0
Xanomeline Low Dose		Week 16	76.0	84.0	-8.0
Xanomeline Low Dose		Week 2	88.0	88.0	0.0
Xanomeline Low Dose		Week 2	84.0	84.0	0.0
Xanomeline Low Dose		Week 2	84.0	84.0	0.0
Xanomeline Low Dose		Week 20	60.0	88.0	-28.0
Xanomeline Low Dose		Week 20	64.0	84.0	-20.0
Xanomeline Low Dose		Week 20	60.0	84.0	-24.0
Xanomeline Low Dose		Week 24	68.0	88.0	-20.0
Xanomeline Low Dose		Week 24	64.0	84.0	-20.0
Xanomeline Low Dose		Week 24	64.0	84.0	-20.0
Xanomeline Low Dose		Week 26	84.0	88.0	-4.0
Xanomeline Low Dose		Week 26	80.0	84.0	-4.0
Xanomeline Low Dose		Week 26	80.0	84.0	-4.0
Xanomeline Low Dose		Week 4	80.0	88.0	-8.0
Xanomeline Low Dose		Week 4	80.0	84.0	-4.0
Xanomeline Low Dose		Week 4	76.0	84.0	-8.0
Xanomeline Low Dose		Week 6	80.0	88.0	-8.0
Xanomeline Low Dose		Week 6	80.0	84.0	-4.0
Xanomeline Low Dose		Week 6	76.0	84.0	-8.0
Xanomeline Low Dose		Week 8	92.0	88.0	4.0
Xanomeline Low Dose		Week 8	88.0	84.0	4.0
Xanomeline Low Dose		Week 8	88.0	84.0	4.0
Xanomeline Low Dose			96.0	88.0
Xanomeline Low Dose			92.0	84.0
Xanomeline Low Dose			92.0	84.0
Xanomeline Low Dose			76.0	88.0
Xanomeline Low Dose			72.0	84.0
Xanomeline Low Dose			72.0	84.0
Xanomeline High Dose		Week 12	64.0	56.0	8.0
Xanomeline High Dose		Week 12	64.0	56.0	8.0
Xanomeline High Dose		Week 12	60.0	60.0	0.0
Xanomeline High Dose		Week 16	64.0	56.0	8.0
Xanomeline High Dose		Week 16	64.0	56.0	8.0
Xanomeline High Dose		Week 16	60.0	60.0	0.0
Xanomeline High Dose		Week 2	88.0	56.0	32.0
Xanomeline High Dose		Week 2	76.0	56.0	20.0
Xanomeline High Dose		Week 2	76.0	60.0	16.0
Xanomeline High Dose		Week 20	72.0	56.0	16.0
Xanomeline High Dose		Week 20	72.0	56.0	16.0
Xanomeline High Dose		Week 20	72.0	60.0	12.0
Xanomeline High Dose		Week 24	68.0	56.0	12.0
Xanomeline High Dose		Week 24	64.0	56.0	8.0
Xanomeline High Dose		Week 24	64.0	60.0	4.0
Xanomeline High Dose		Week 26	60.0	56.0	4.0
Xanomeline High Dose		Week 26	60.0	56.0	4.0
Xanomeline High Dose		Week 26	60.0	60.0	0.0
Xanomeline High Dose		Week 4	72.0	56.0	16.0
Xanomeline High Dose		Week 4	72.0	56.0	16.0
Xanomeline High Dose		Week 4	68.0	60.0	8.0
Xanomeline High Dose		Week 6	60.0	56.0	4.0
Xanomeline High Dose		Week 6	62.0	56.0	6.0
Xanomeline High Dose		Week 6	62.0	60.0	2.0
Xanomeline High Dose		Week 8	64.0	56.0	8.0
Xanomeline High Dose		Week 8	64.0	56.0	8.0
Xanomeline High Dose		Week 8	60.0	60.0	0.0
Xanomeline High Dose			72.0	56.0
Xanomeline High Dose			68.0	56.0
Xanomeline High Dose			68.0	60.0
Xanomeline High Dose			68.0	56.0
Xanomeline High Dose			64.0	56.0
Xanomeline High Dose			64.0	60.0
Placebo		Week 12	64.0	80.0	-16.0
Placebo		Week 12	60.0	80.0	-20.0
Placebo		Week 12	64.0	76.0	-12.0
Placebo		Week 16	72.0	80.0	-8.0
Placebo		Week 16	68.0	80.0	-12.0
Placebo		Week 16	68.0	76.0	-8.0
Placebo		Week 2	60.0	80.0	-20.0
Placebo		Week 2	60.0	80.0	-20.0
Placebo		Week 2	56.0	76.0	-20.0
Placebo		Week 4	76.0	80.0	-4.0
Placebo		Week 4	72.0	80.0	-8.0
Placebo		Week 4	72.0	76.0	-4.0
Placebo		Week 6	68.0	80.0	-12.0
Placebo		Week 6	72.0	80.0	-8.0
Placebo		Week 6	68.0	76.0	-8.0
Placebo		Week 8	68.0	80.0	-12.0
Placebo		Week 8	64.0	80.0	-16.0
Placebo		Week 8	64.0	76.0	-12.0
Placebo			84.0	80.0
Placebo			80.0	80.0
Placebo			80.0	76.0
Placebo			80.0	80.0
Placebo			80.0	80.0
Placebo			76.0	76.0
Xanomeline Low Dose		Week 2	74.0	72.0	2.0
Xanomeline Low Dose		Week 2	80.0	72.0	8.0
Xanomeline Low Dose		Week 2	76.0	68.0	8.0
Placebo		Week 2	76.0	80.0	-4.0
Placebo		Week 2	76.0	76.0	0.0
Placebo		Week 2	72.0	76.0	-4.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 6	76.0	80.0	-4.0
Placebo		Week 6	76.0	76.0	0.0
Placebo		Week 6	72.0	76.0	-4.0
Placebo			76.0	80.0
Placebo			74.0	76.0
Placebo			76.0	76.0
Placebo			80.0	80.0
Placebo			80.0	76.0
Placebo			76.0	76.0
Xanomeline High Dose		Week 2	76.0	64.0	12.0
Xanomeline High Dose		Week 2	72.0	60.0	12.0
Xanomeline High Dose		Week 2	72.0	60.0	12.0
Xanomeline High Dose		Week 4	80.0	64.0	16.0
Xanomeline High Dose		Week 4	76.0	60.0	16.0
Xanomeline High Dose		Week 4	80.0	60.0	20.0
Xanomeline High Dose		Week 6	64.0	64.0	0.0
Xanomeline High Dose		Week 6	72.0	60.0	12.0
Xanomeline High Dose		Week 6	68.0	60.0	8.0
Xanomeline High Dose		Week 8	72.0	64.0	8.0
Xanomeline High Dose		Week 8	72.0	60.0	12.0
Xanomeline High Dose		Week 8	68.0	60.0	8.0
Xanomeline High Dose			76.0	64.0
Xanomeline High Dose			76.0	60.0
Xanomeline High Dose			72.0	60.0
Xanomeline High Dose			76.0	64.0
Xanomeline High Dose			72.0	60.0
Xanomeline High Dose			72.0	60.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	64.0	64.0	0.0
Xanomeline Low Dose		Week 2	64.0	64.0	0.0
Xanomeline Low Dose		Week 4	88.0	68.0	20.0
Xanomeline Low Dose		Week 4	84.0	64.0	20.0
Xanomeline Low Dose		Week 4	84.0	64.0	20.0
Xanomeline Low Dose		Week 6	72.0	68.0	4.0
Xanomeline Low Dose		Week 6	72.0	64.0	8.0
Xanomeline Low Dose		Week 6	72.0	64.0	8.0
Xanomeline Low Dose		Week 8	80.0	68.0	12.0
Xanomeline Low Dose		Week 8	76.0	64.0	12.0
Xanomeline Low Dose		Week 8	80.0	64.0	16.0
Xanomeline Low Dose			64.0	68.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			68.0	68.0
Xanomeline Low Dose			64.0	64.0
Xanomeline Low Dose			68.0	64.0
Placebo		Week 2	68.0	56.0	12.0
Placebo		Week 2	64.0	56.0	8.0
Placebo		Week 2	64.0	60.0	4.0
Placebo		Week 4	72.0	56.0	16.0
Placebo		Week 4	76.0	56.0	20.0
Placebo		Week 4	76.0	60.0	16.0
Placebo			64.0	56.0
Placebo			60.0	56.0
Placebo			60.0	60.0
Placebo		Week 12	96.0	96.0	0.0
Placebo		Week 12	96.0	88.0	8.0
Placebo		Week 12	92.0	88.0	4.0
Placebo		Week 16	84.0	96.0	-12.0
Placebo		Week 16	80.0	88.0	-8.0
Placebo		Week 16	80.0	88.0	-8.0
Placebo		Week 2	88.0	96.0	-8.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 2	84.0	88.0	-4.0
Placebo		Week 4	88.0	96.0	-8.0
Placebo		Week 4	84.0	88.0	-4.0
Placebo		Week 4	84.0	88.0	-4.0
Placebo		Week 6	100.0	96.0	4.0
Placebo		Week 6	96.0	88.0	8.0
Placebo		Week 6	96.0	88.0	8.0
Placebo		Week 8	84.0	96.0	-12.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo		Week 8	80.0	88.0	-8.0
Placebo			96.0	96.0
Placebo			92.0	88.0
Placebo			92.0	88.0
Placebo			78.0	96.0
Placebo			76.0	88.0
Placebo			76.0	88.0
Xanomeline High Dose		Week 12	64.0	72.0	-8.0
Xanomeline High Dose		Week 12	60.0	72.0	-12.0
Xanomeline High Dose		Week 12	64.0	72.0	-8.0
Xanomeline High Dose		Week 16	76.0	72.0	4.0
Xanomeline High Dose		Week 16	76.0	72.0	4.0
Xanomeline High Dose		Week 16	72.0	72.0	0.0
Xanomeline High Dose		Week 2	76.0	72.0	4.0
Xanomeline High Dose		Week 2	76.0	72.0	4.0
Xanomeline High Dose		Week 2	72.0	72.0	0.0
Xanomeline High Dose		Week 20	64.0	72.0	-8.0
Xanomeline High Dose		Week 20	64.0	72.0	-8.0
Xanomeline High Dose		Week 20	64.0	72.0	-8.0
Xanomeline High Dose		Week 24	76.0	72.0	4.0
Xanomeline High Dose		Week 24	76.0	72.0	4.0
Xanomeline High Dose		Week 24	76.0	72.0	4.0
Xanomeline High Dose		Week 26	72.0	72.0	0.0
Xanomeline High Dose		Week 26	72.0	72.0	0.0
Xanomeline High Dose		Week 26	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	64.0	72.0	-8.0
Xanomeline High Dose		Week 4	68.0	72.0	-4.0
Xanomeline High Dose		Week 6	76.0	72.0	4.0
Xanomeline High Dose		Week 6	76.0	72.0	4.0
Xanomeline High Dose		Week 6	72.0	72.0	0.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 8	80.0	72.0	8.0
Xanomeline High Dose		Week 8	84.0	72.0	12.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			76.0	72.0
Xanomeline High Dose			68.0	72.0
Xanomeline High Dose			68.0	72.0
Xanomeline High Dose			64.0	72.0
Xanomeline Low Dose		Week 12	72.0	64.0	8.0
Xanomeline Low Dose		Week 12	72.0	60.0	12.0
Xanomeline Low Dose		Week 12	68.0	60.0	8.0
Xanomeline Low Dose		Week 16	64.0	64.0	0.0
Xanomeline Low Dose		Week 16	60.0	60.0	0.0
Xanomeline Low Dose		Week 16	60.0	60.0	0.0
Xanomeline Low Dose		Week 2	80.0	64.0	16.0
Xanomeline Low Dose		Week 2	76.0	60.0	16.0
Xanomeline Low Dose		Week 2	76.0	60.0	16.0
Xanomeline Low Dose		Week 20	60.0	64.0	-4.0
Xanomeline Low Dose		Week 20	64.0	60.0	4.0
Xanomeline Low Dose		Week 20	64.0	60.0	4.0
Xanomeline Low Dose		Week 4	80.0	64.0	16.0
Xanomeline Low Dose		Week 4	76.0	60.0	16.0
Xanomeline Low Dose		Week 4	76.0	60.0	16.0
Xanomeline Low Dose		Week 6	68.0	64.0	4.0
Xanomeline Low Dose		Week 6	64.0	60.0	4.0
Xanomeline Low Dose		Week 6	68.0	60.0	8.0
Xanomeline Low Dose		Week 8	68.0	64.0	4.0
Xanomeline Low Dose		Week 8	68.0	60.0	8.0
Xanomeline Low Dose		Week 8	64.0	60.0	4.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			72.0	60.0
Xanomeline Low Dose			72.0	60.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			68.0	60.0
Xanomeline Low Dose			64.0	60.0
Placebo		Week 12	80.0	84.0	-4.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 12	80.0	80.0	0.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 2	80.0	84.0	-4.0
Placebo		Week 2	76.0	80.0	-4.0
Placebo		Week 2	76.0	80.0	-4.0
Placebo		Week 20	80.0	84.0	-4.0
Placebo		Week 20	76.0	80.0	-4.0
Placebo		Week 20	76.0	80.0	-4.0
Placebo		Week 24	84.0	84.0	0.0
Placebo		Week 24	84.0	80.0	4.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 26	84.0	84.0	0.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 26	80.0	80.0	0.0
Placebo		Week 4	76.0	84.0	-8.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 6	88.0	84.0	4.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 8	80.0	84.0	-4.0
Placebo		Week 8	76.0	80.0	-4.0
Placebo		Week 8	76.0	80.0	-4.0
Placebo			68.0	84.0
Placebo			64.0	80.0
Placebo			64.0	80.0
Placebo			84.0	84.0
Placebo			80.0	80.0
Placebo			80.0	80.0
Xanomeline Low Dose		Week 12	72.0	76.0	-4.0
Xanomeline Low Dose		Week 12	76.0	76.0	0.0
Xanomeline Low Dose		Week 12	76.0	72.0	4.0
Xanomeline Low Dose		Week 16	60.0	76.0	-16.0
Xanomeline Low Dose		Week 16	56.0	76.0	-20.0
Xanomeline Low Dose		Week 16	56.0	72.0	-16.0
Xanomeline Low Dose		Week 2	116.0	76.0	40.0
Xanomeline Low Dose		Week 2	112.0	76.0	36.0
Xanomeline Low Dose		Week 2	112.0	72.0	40.0
Xanomeline Low Dose		Week 4	88.0	76.0	12.0
Xanomeline Low Dose		Week 4	84.0	76.0	8.0
Xanomeline Low Dose		Week 4	84.0	72.0	12.0
Xanomeline Low Dose		Week 6	76.0	76.0	0.0
Xanomeline Low Dose		Week 6	72.0	76.0	-4.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 8	84.0	76.0	8.0
Xanomeline Low Dose		Week 8	78.0	76.0	2.0
Xanomeline Low Dose		Week 8	78.0	72.0	6.0
Xanomeline Low Dose			60.0	76.0
Xanomeline Low Dose			56.0	76.0
Xanomeline Low Dose			60.0	72.0
Xanomeline Low Dose			84.0	76.0
Xanomeline Low Dose			80.0	76.0
Xanomeline Low Dose			80.0	72.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	80.0	76.0	4.0
Xanomeline High Dose		Week 12	76.0	76.0	0.0
Xanomeline High Dose		Week 16	80.0	80.0	0.0
Xanomeline High Dose		Week 16	80.0	76.0	4.0
Xanomeline High Dose		Week 16	76.0	76.0	0.0
Xanomeline High Dose		Week 2	74.0	80.0	-6.0
Xanomeline High Dose		Week 2	68.0	76.0	-8.0
Xanomeline High Dose		Week 2	72.0	76.0	-4.0
Xanomeline High Dose		Week 20	76.0	80.0	-4.0
Xanomeline High Dose		Week 20	80.0	76.0	4.0
Xanomeline High Dose		Week 20	76.0	76.0	0.0
Xanomeline High Dose		Week 24	84.0	80.0	4.0
Xanomeline High Dose		Week 24	80.0	76.0	4.0
Xanomeline High Dose		Week 24	80.0	76.0	4.0
Xanomeline High Dose		Week 26	92.0	80.0	12.0
Xanomeline High Dose		Week 26	88.0	76.0	12.0
Xanomeline High Dose		Week 26	88.0	76.0	12.0
Xanomeline High Dose		Week 4	92.0	80.0	12.0
Xanomeline High Dose		Week 4	88.0	76.0	12.0
Xanomeline High Dose		Week 4	88.0	76.0	12.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 6	76.0	76.0	0.0
Xanomeline High Dose		Week 6	76.0	76.0	0.0
Xanomeline High Dose		Week 8	80.0	80.0	0.0
Xanomeline High Dose		Week 8	80.0	76.0	4.0
Xanomeline High Dose		Week 8	84.0	76.0	8.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			80.0	76.0
Xanomeline High Dose			76.0	76.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			84.0	76.0
Xanomeline High Dose			84.0	76.0
Xanomeline High Dose		Week 2	84.0	80.0	4.0
Xanomeline High Dose		Week 2	92.0	92.0	0.0
Xanomeline High Dose		Week 2	92.0	88.0	4.0
Xanomeline High Dose			68.0	80.0
Xanomeline High Dose			80.0	92.0
Xanomeline High Dose			84.0	88.0
Placebo		Week 12	76.0	60.0	16.0
Placebo		Week 12	96.0	72.0	24.0
Placebo		Week 12	104.0	72.0	32.0
Placebo		Week 16	64.0	60.0	4.0
Placebo		Week 16	76.0	72.0	4.0
Placebo		Week 16	88.0	72.0	16.0
Placebo		Week 2	68.0	60.0	8.0
Placebo		Week 2	84.0	72.0	12.0
Placebo		Week 2	84.0	72.0	12.0
Placebo		Week 20	68.0	60.0	8.0
Placebo		Week 20	80.0	72.0	8.0
Placebo		Week 20	84.0	72.0	12.0
Placebo		Week 24	64.0	60.0	4.0
Placebo		Week 24	80.0	72.0	8.0
Placebo		Week 24	80.0	72.0	8.0
Placebo		Week 26	68.0	60.0	8.0
Placebo		Week 26	76.0	72.0	4.0
Placebo		Week 26	80.0	72.0	8.0
Placebo		Week 4	64.0	60.0	4.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 4	76.0	72.0	4.0
Placebo		Week 6	72.0	60.0	12.0
Placebo		Week 6	84.0	72.0	12.0
Placebo		Week 6	80.0	72.0	8.0
Placebo		Week 8	68.0	60.0	8.0
Placebo		Week 8	84.0	72.0	12.0
Placebo		Week 8	84.0	72.0	12.0
Placebo			80.0	60.0
Placebo			92.0	72.0
Placebo			96.0	72.0
Placebo			72.0	60.0
Placebo			76.0	72.0
Placebo			80.0	72.0
Xanomeline Low Dose		Week 2	60.0	72.0	-12.0
Xanomeline Low Dose		Week 2	64.0	68.0	-4.0
Xanomeline Low Dose		Week 2	64.0	68.0	-4.0
Xanomeline Low Dose		Week 4	60.0	72.0	-12.0
Xanomeline Low Dose		Week 4	80.0	68.0	12.0
Xanomeline Low Dose		Week 4	80.0	68.0	12.0
Xanomeline Low Dose		Week 6	64.0	72.0	-8.0
Xanomeline Low Dose		Week 6	60.0	68.0	-8.0
Xanomeline Low Dose		Week 6	64.0	68.0	-4.0
Xanomeline Low Dose		Week 8	64.0	72.0	-8.0
Xanomeline Low Dose		Week 8	68.0	68.0	0.0
Xanomeline Low Dose		Week 8	68.0	68.0	0.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose			64.0	68.0
Xanomeline Low Dose			64.0	68.0
Xanomeline Low Dose			64.0	72.0
Xanomeline Low Dose			60.0	68.0
Xanomeline Low Dose			68.0	68.0
Xanomeline Low Dose		Week 12	82.0	80.0	2.0
Xanomeline Low Dose		Week 12	80.0	80.0	0.0
Xanomeline Low Dose		Week 12	68.0	96.0	-28.0
Xanomeline Low Dose		Week 16	68.0	80.0	-12.0
Xanomeline Low Dose		Week 16	76.0	80.0	-4.0
Xanomeline Low Dose		Week 16	76.0	96.0	-20.0
Xanomeline Low Dose		Week 2	88.0	80.0	8.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	102.0	96.0	6.0
Xanomeline Low Dose		Week 20	72.0	80.0	-8.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	71.0	96.0	-25.0
Xanomeline Low Dose		Week 24	80.0	80.0	0.0
Xanomeline Low Dose		Week 24	88.0	80.0	8.0
Xanomeline Low Dose		Week 24	96.0	96.0	0.0
Xanomeline Low Dose		Week 26	68.0	80.0	-12.0
Xanomeline Low Dose		Week 26	92.0	80.0	12.0
Xanomeline Low Dose		Week 26	82.0	96.0	-14.0
Xanomeline Low Dose		Week 4	82.0	80.0	2.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	100.0	96.0	4.0
Xanomeline Low Dose		Week 6	76.0	80.0	-4.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	88.0	96.0	-8.0
Xanomeline Low Dose		Week 8	76.0	80.0	-4.0
Xanomeline Low Dose		Week 8	68.0	80.0	-12.0
Xanomeline Low Dose		Week 8	100.0	96.0	4.0
Xanomeline Low Dose			100.0	80.0
Xanomeline Low Dose			68.0	80.0
Xanomeline Low Dose			80.0	96.0
Xanomeline Low Dose			88.0	80.0
Xanomeline Low Dose			96.0	80.0
Xanomeline Low Dose			96.0	96.0
Xanomeline Low Dose		Week 12	78.0	85.0	-7.0
Xanomeline Low Dose		Week 12	76.0	84.0	-8.0
Xanomeline Low Dose		Week 12	80.0	88.0	-8.0
Xanomeline Low Dose		Week 16	72.0	85.0	-13.0
Xanomeline Low Dose		Week 16	71.0	84.0	-13.0
Xanomeline Low Dose		Week 16	78.0	88.0	-10.0
Xanomeline Low Dose		Week 2	68.0	85.0	-17.0
Xanomeline Low Dose		Week 2	74.0	84.0	-10.0
Xanomeline Low Dose		Week 2	80.0	88.0	-8.0
Xanomeline Low Dose		Week 20	66.0	85.0	-19.0
Xanomeline Low Dose		Week 20	68.0	84.0	-16.0
Xanomeline Low Dose		Week 20	71.0	88.0	-17.0
Xanomeline Low Dose		Week 24	80.0	85.0	-5.0
Xanomeline Low Dose		Week 24	81.0	84.0	-3.0
Xanomeline Low Dose		Week 24	80.0	88.0	-8.0
Xanomeline Low Dose		Week 26	65.0	85.0	-20.0
Xanomeline Low Dose		Week 26	62.0	84.0	-22.0
Xanomeline Low Dose		Week 26	62.0	88.0	-26.0
Xanomeline Low Dose		Week 4	64.0	85.0	-21.0
Xanomeline Low Dose		Week 4	63.0	84.0	-21.0
Xanomeline Low Dose		Week 4	62.0	88.0	-26.0
Xanomeline Low Dose		Week 6	84.0	85.0	-1.0
Xanomeline Low Dose		Week 6	88.0	84.0	4.0
Xanomeline Low Dose		Week 6	89.0	88.0	1.0
Xanomeline Low Dose		Week 8	82.0	85.0	-3.0
Xanomeline Low Dose		Week 8	92.0	84.0	8.0
Xanomeline Low Dose		Week 8	92.0	88.0	4.0
Xanomeline Low Dose			60.0	85.0
Xanomeline Low Dose			80.0	84.0
Xanomeline Low Dose			78.0	88.0
Xanomeline High Dose		Week 12	80.0	82.0	-2.0
Xanomeline High Dose		Week 12	80.0	80.0	0.0
Xanomeline High Dose		Week 12	62.0	82.0	-20.0
Xanomeline High Dose		Week 16	72.0	82.0	-10.0
Xanomeline High Dose		Week 16	82.0	80.0	2.0
Xanomeline High Dose		Week 16	80.0	82.0	-2.0
Xanomeline High Dose		Week 2	75.0	82.0	-7.0
Xanomeline High Dose		Week 2	78.0	80.0	-2.0
Xanomeline High Dose		Week 2	78.0	82.0	-4.0
Xanomeline High Dose		Week 20	80.0	82.0	-2.0
Xanomeline High Dose		Week 20	82.0	80.0	2.0
Xanomeline High Dose		Week 20	72.0	82.0	-10.0
Xanomeline High Dose		Week 24	76.0	82.0	-6.0
Xanomeline High Dose		Week 24	60.0	80.0	-20.0
Xanomeline High Dose		Week 24	76.0	82.0	-6.0
Xanomeline High Dose		Week 26	60.0	82.0	-22.0
Xanomeline High Dose		Week 26	80.0	80.0	0.0
Xanomeline High Dose		Week 26	72.0	82.0	-10.0
Xanomeline High Dose		Week 4	68.0	82.0	-14.0
Xanomeline High Dose		Week 4	56.0	80.0	-24.0
Xanomeline High Dose		Week 4	76.0	82.0	-6.0
Xanomeline High Dose		Week 6	68.0	82.0	-14.0
Xanomeline High Dose		Week 6	88.0	80.0	8.0
Xanomeline High Dose		Week 6	88.0	82.0	6.0
Xanomeline High Dose		Week 8	62.0	82.0	-20.0
Xanomeline High Dose		Week 8	76.0	80.0	-4.0
Xanomeline High Dose		Week 8	76.0	82.0	-6.0
Xanomeline High Dose			68.0	82.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			93.0	82.0
Xanomeline High Dose			76.0	82.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			68.0	82.0
Xanomeline High Dose		Week 2	64.0	82.0	-18.0
Xanomeline High Dose		Week 2	68.0	68.0	0.0
Xanomeline High Dose		Week 2	68.0	80.0	-12.0
Xanomeline High Dose		Week 4	88.0	82.0	6.0
Xanomeline High Dose		Week 4	82.0	68.0	14.0
Xanomeline High Dose		Week 4	82.0	80.0	2.0
Xanomeline High Dose			64.0	82.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			80.0	80.0
Xanomeline High Dose			86.0	82.0
Xanomeline High Dose			88.0	68.0
Xanomeline High Dose			76.0	80.0
Placebo		Week 12	68.0	56.0	12.0
Placebo		Week 12	68.0	56.0	12.0
Placebo		Week 12	68.0	68.0	0.0
Placebo		Week 16	56.0	56.0	0.0
Placebo		Week 16	60.0	56.0	4.0
Placebo		Week 16	68.0	68.0	0.0
Placebo		Week 2	60.0	56.0	4.0
Placebo		Week 2	60.0	56.0	4.0
Placebo		Week 2	62.0	68.0	-6.0
Placebo		Week 20	80.0	56.0	24.0
Placebo		Week 20	76.0	56.0	20.0
Placebo		Week 20	68.0	68.0	0.0
Placebo		Week 24	56.0	56.0	0.0
Placebo		Week 24	52.0	56.0	-4.0
Placebo		Week 24	60.0	68.0	-8.0
Placebo		Week 26	68.0	56.0	12.0
Placebo		Week 26	68.0	56.0	12.0
Placebo		Week 26	88.0	68.0	20.0
Placebo		Week 4	52.0	56.0	-4.0
Placebo		Week 4	62.0	56.0	6.0
Placebo		Week 4	68.0	68.0	0.0
Placebo		Week 6	72.0	56.0	16.0
Placebo		Week 6	68.0	56.0	12.0
Placebo		Week 6	68.0	68.0	0.0
Placebo		Week 8	68.0	56.0	12.0
Placebo		Week 8	76.0	56.0	20.0
Placebo		Week 8	72.0	68.0	4.0
Placebo			60.0	56.0
Placebo			62.0	56.0
Placebo			68.0	68.0
Placebo			60.0	56.0
Placebo			72.0	56.0
Placebo			72.0	68.0
Xanomeline High Dose		Week 12	76.0	76.0	0.0
Xanomeline High Dose		Week 12	68.0	68.0	0.0
Xanomeline High Dose		Week 12	88.0	82.0	6.0
Xanomeline High Dose		Week 16	68.0	76.0	-8.0
Xanomeline High Dose		Week 16	82.0	68.0	14.0
Xanomeline High Dose		Week 16	80.0	82.0	-2.0
Xanomeline High Dose		Week 2	80.0	76.0	4.0
Xanomeline High Dose		Week 2	88.0	68.0	20.0
Xanomeline High Dose		Week 2	88.0	82.0	6.0
Xanomeline High Dose		Week 20	80.0	76.0	4.0
Xanomeline High Dose		Week 20	88.0	68.0	20.0
Xanomeline High Dose		Week 20	68.0	82.0	-14.0
Xanomeline High Dose		Week 24	82.0	76.0	6.0
Xanomeline High Dose		Week 24	88.0	68.0	20.0
Xanomeline High Dose		Week 24	96.0	82.0	14.0
Xanomeline High Dose		Week 26	88.0	76.0	12.0
Xanomeline High Dose		Week 26	88.0	68.0	20.0
Xanomeline High Dose		Week 26	88.0	82.0	6.0
Xanomeline High Dose		Week 4	88.0	76.0	12.0
Xanomeline High Dose		Week 4	93.0	68.0	25.0
Xanomeline High Dose		Week 4	82.0	82.0	0.0
Xanomeline High Dose		Week 6	80.0	76.0	4.0
Xanomeline High Dose		Week 6	93.0	68.0	25.0
Xanomeline High Dose		Week 6	80.0	82.0	-2.0
Xanomeline High Dose		Week 8	76.0	76.0	0.0
Xanomeline High Dose		Week 8	76.0	68.0	8.0
Xanomeline High Dose		Week 8	68.0	82.0	-14.0
Xanomeline High Dose			80.0	76.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			82.0	82.0
Xanomeline High Dose			84.0	76.0
Xanomeline High Dose			80.0	68.0
Xanomeline High Dose			88.0	82.0
Placebo		Week 12	93.0	82.0	11.0
Placebo		Week 12	92.0	82.0	10.0
Placebo		Week 12	96.0	80.0	16.0
Placebo		Week 16	82.0	82.0	0.0
Placebo		Week 16	80.0	82.0	-2.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 2	82.0	82.0	0.0
Placebo		Week 2	80.0	82.0	-2.0
Placebo		Week 2	80.0	80.0	0.0
Placebo		Week 20	80.0	82.0	-2.0
Placebo		Week 20	80.0	82.0	-2.0
Placebo		Week 20	92.0	80.0	12.0
Placebo		Week 24	76.0	82.0	-6.0
Placebo		Week 24	76.0	82.0	-6.0
Placebo		Week 24	76.0	80.0	-4.0
Placebo		Week 26	94.0	82.0	12.0
Placebo		Week 26	92.0	82.0	10.0
Placebo		Week 26	92.0	80.0	12.0
Placebo		Week 4	62.0	82.0	-20.0
Placebo		Week 4	62.0	82.0	-20.0
Placebo		Week 4	88.0	80.0	8.0
Placebo		Week 6	68.0	82.0	-14.0
Placebo		Week 6	82.0	82.0	0.0
Placebo		Week 6	93.0	80.0	13.0
Placebo		Week 8	72.0	82.0	-10.0
Placebo		Week 8	72.0	82.0	-10.0
Placebo		Week 8	68.0	80.0	-12.0
Placebo			82.0	82.0
Placebo			82.0	82.0
Placebo			82.0	80.0
Placebo			68.0	82.0
Placebo			72.0	82.0
Placebo			88.0	80.0
Placebo		Week 12	80.0	72.0	8.0
Placebo		Week 12	80.0	78.0	2.0
Placebo		Week 12	80.0	77.0	3.0
Placebo		Week 16	70.0	72.0	-2.0
Placebo		Week 16	71.0	78.0	-7.0
Placebo		Week 16	70.0	77.0	-7.0
Placebo		Week 2	70.0	72.0	-2.0
Placebo		Week 2	78.0	78.0	0.0
Placebo		Week 2	80.0	77.0	3.0
Placebo		Week 20	68.0	72.0	-4.0
Placebo		Week 20	65.0	78.0	-13.0
Placebo		Week 20	68.0	77.0	-9.0
Placebo		Week 24	71.0	72.0	-1.0
Placebo		Week 24	72.0	78.0	-6.0
Placebo		Week 24	71.0	77.0	-6.0
Placebo		Week 26	80.0	72.0	8.0
Placebo		Week 26	81.0	78.0	3.0
Placebo		Week 26	81.0	77.0	4.0
Placebo		Week 4	71.0	72.0	-1.0
Placebo		Week 4	70.0	78.0	-8.0
Placebo		Week 4	71.0	77.0	-6.0
Placebo		Week 6	80.0	72.0	8.0
Placebo		Week 6	80.0	78.0	2.0
Placebo		Week 6	80.0	77.0	3.0
Placebo		Week 8	70.0	72.0	-2.0
Placebo		Week 8	70.0	78.0	-8.0
Placebo		Week 8	65.0	77.0	-12.0
Placebo			68.0	72.0
Placebo			72.0	78.0
Placebo			72.0	77.0
Xanomeline Low Dose		Week 12	90.0	68.0	22.0
Xanomeline Low Dose		Week 12	88.0	70.0	18.0
Xanomeline Low Dose		Week 12	89.0	70.0	19.0
Xanomeline Low Dose		Week 2	78.0	68.0	10.0
Xanomeline Low Dose		Week 2	79.0	70.0	9.0
Xanomeline Low Dose		Week 2	88.0	70.0	18.0
Xanomeline Low Dose		Week 4	88.0	68.0	20.0
Xanomeline Low Dose		Week 4	95.0	70.0	25.0
Xanomeline Low Dose		Week 4	100.0	70.0	30.0
Xanomeline Low Dose		Week 6	83.0	68.0	15.0
Xanomeline Low Dose		Week 6	82.0	70.0	12.0
Xanomeline Low Dose		Week 6	84.0	70.0	14.0
Xanomeline Low Dose		Week 8	88.0	68.0	20.0
Xanomeline Low Dose		Week 8	88.0	70.0	18.0
Xanomeline Low Dose		Week 8	84.0	70.0	14.0
Xanomeline Low Dose			95.0	68.0
Xanomeline Low Dose			88.0	70.0
Xanomeline Low Dose			89.0	70.0
Xanomeline Low Dose			86.0	68.0
Xanomeline Low Dose			88.0	70.0
Xanomeline Low Dose			88.0	70.0
Placebo		Week 12	70.0	72.0	-2.0
Placebo		Week 12	76.0	76.0	0.0
Placebo		Week 12	78.0	74.0	4.0
Placebo		Week 16	66.0	72.0	-6.0
Placebo		Week 16	78.0	76.0	2.0
Placebo		Week 16	70.0	74.0	-4.0
Placebo		Week 2	80.0	72.0	8.0
Placebo		Week 2	76.0	76.0	0.0
Placebo		Week 2	80.0	74.0	6.0
Placebo		Week 20	64.0	72.0	-8.0
Placebo		Week 20	78.0	76.0	2.0
Placebo		Week 20	74.0	74.0	0.0
Placebo		Week 24	68.0	72.0	-4.0
Placebo		Week 24	78.0	76.0	2.0
Placebo		Week 24	78.0	74.0	4.0
Placebo		Week 26	64.0	72.0	-8.0
Placebo		Week 26	74.0	76.0	-2.0
Placebo		Week 26	78.0	74.0	4.0
Placebo		Week 4	78.0	72.0	6.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	80.0	74.0	6.0
Placebo		Week 6	66.0	72.0	-6.0
Placebo		Week 6	80.0	76.0	4.0
Placebo		Week 6	80.0	74.0	6.0
Placebo		Week 8	76.0	72.0	4.0
Placebo		Week 8	78.0	76.0	2.0
Placebo		Week 8	80.0	74.0	6.0
Placebo			80.0	72.0
Placebo			82.0	76.0
Placebo			80.0	74.0
Placebo			70.0	72.0
Placebo			78.0	76.0
Placebo			74.0	74.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	78.0	78.0	0.0
Xanomeline Low Dose		Week 4	80.0	80.0	0.0
Xanomeline Low Dose		Week 4	78.0	80.0	-2.0
Xanomeline Low Dose		Week 4	78.0	78.0	0.0
Xanomeline Low Dose		Week 6	78.0	80.0	-2.0
Xanomeline Low Dose		Week 6	86.0	80.0	6.0
Xanomeline Low Dose		Week 6	72.0	78.0	-6.0
Xanomeline Low Dose		Week 8	76.0	80.0	-4.0
Xanomeline Low Dose		Week 8	78.0	80.0	-2.0
Xanomeline Low Dose		Week 8	80.0	78.0	2.0
Xanomeline Low Dose			66.0	80.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			76.0	78.0
Xanomeline Low Dose			80.0	80.0
Xanomeline Low Dose			78.0	80.0
Xanomeline Low Dose			80.0	78.0
Xanomeline Low Dose		Week 12	76.0	78.0	-2.0
Xanomeline Low Dose		Week 12	84.0	88.0	-4.0
Xanomeline Low Dose		Week 12	86.0	88.0	-2.0
Xanomeline Low Dose		Week 16	70.0	78.0	-8.0
Xanomeline Low Dose		Week 16	82.0	88.0	-6.0
Xanomeline Low Dose		Week 16	84.0	88.0	-4.0
Xanomeline Low Dose		Week 2	74.0	78.0	-4.0
Xanomeline Low Dose		Week 2	86.0	88.0	-2.0
Xanomeline Low Dose		Week 2	80.0	88.0	-8.0
Xanomeline Low Dose		Week 20	72.0	78.0	-6.0
Xanomeline Low Dose		Week 20	74.0	88.0	-14.0
Xanomeline Low Dose		Week 20	72.0	88.0	-16.0
Xanomeline Low Dose		Week 24	66.0	78.0	-12.0
Xanomeline Low Dose		Week 24	82.0	88.0	-6.0
Xanomeline Low Dose		Week 24	74.0	88.0	-14.0
Xanomeline Low Dose		Week 26	68.0	78.0	-10.0
Xanomeline Low Dose		Week 26	76.0	88.0	-12.0
Xanomeline Low Dose		Week 26	76.0	88.0	-12.0
Xanomeline Low Dose		Week 4	70.0	78.0	-8.0
Xanomeline Low Dose		Week 4	78.0	88.0	-10.0
Xanomeline Low Dose		Week 4	78.0	88.0	-10.0
Xanomeline Low Dose		Week 6	90.0	78.0	12.0
Xanomeline Low Dose		Week 6	96.0	88.0	8.0
Xanomeline Low Dose		Week 6	96.0	88.0	8.0
Xanomeline Low Dose		Week 8	84.0	78.0	6.0
Xanomeline Low Dose		Week 8	104.0	88.0	16.0
Xanomeline Low Dose		Week 8	92.0	88.0	4.0
Xanomeline High Dose		Week 12	62.0	82.0	-20.0
Xanomeline High Dose		Week 12	80.0	98.0	-18.0
Xanomeline High Dose		Week 12	86.0	96.0	-10.0
Xanomeline High Dose		Week 16	58.0	82.0	-24.0
Xanomeline High Dose		Week 16	70.0	98.0	-28.0
Xanomeline High Dose		Week 16	86.0	96.0	-10.0
Xanomeline High Dose		Week 2	72.0	82.0	-10.0
Xanomeline High Dose		Week 2	88.0	98.0	-10.0
Xanomeline High Dose		Week 2	90.0	96.0	-6.0
Xanomeline High Dose		Week 20	86.0	82.0	4.0
Xanomeline High Dose		Week 20	92.0	98.0	-6.0
Xanomeline High Dose		Week 20	100.0	96.0	4.0
Xanomeline High Dose		Week 24	48.0	82.0	-34.0
Xanomeline High Dose		Week 24	62.0	98.0	-36.0
Xanomeline High Dose		Week 24	56.0	96.0	-40.0
Xanomeline High Dose		Week 26	56.0	82.0	-26.0
Xanomeline High Dose		Week 26	70.0	98.0	-28.0
Xanomeline High Dose		Week 26	64.0	96.0	-32.0
Xanomeline High Dose		Week 4	84.0	82.0	2.0
Xanomeline High Dose		Week 4	112.0	98.0	14.0
Xanomeline High Dose		Week 4	94.0	96.0	-2.0
Xanomeline High Dose		Week 6	64.0	82.0	-18.0
Xanomeline High Dose		Week 6	68.0	98.0	-30.0
Xanomeline High Dose		Week 6	64.0	96.0	-32.0
Xanomeline High Dose		Week 8	70.0	82.0	-12.0
Xanomeline High Dose		Week 8	104.0	98.0	6.0
Xanomeline High Dose		Week 8	98.0	96.0	2.0
Xanomeline High Dose			84.0	82.0
Xanomeline High Dose			94.0	98.0
Xanomeline High Dose			98.0	96.0
Placebo		Week 12	80.0	76.0	4.0
Placebo		Week 12	84.0	82.0	2.0
Placebo		Week 12	88.0	78.0	10.0
Placebo		Week 16	76.0	76.0	0.0
Placebo		Week 16	72.0	82.0	-10.0
Placebo		Week 16	76.0	78.0	-2.0
Placebo		Week 2	74.0	76.0	-2.0
Placebo		Week 2	76.0	82.0	-6.0
Placebo		Week 2	88.0	78.0	10.0
Placebo		Week 20	72.0	76.0	-4.0
Placebo		Week 20	88.0	82.0	6.0
Placebo		Week 20	84.0	78.0	6.0
Placebo		Week 24	72.0	76.0	-4.0
Placebo		Week 24	74.0	82.0	-8.0
Placebo		Week 24	78.0	78.0	0.0
Placebo		Week 26	74.0	76.0	-2.0
Placebo		Week 26	86.0	82.0	4.0
Placebo		Week 26	86.0	78.0	8.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 4	74.0	82.0	-8.0
Placebo		Week 4	72.0	78.0	-6.0
Placebo		Week 6	74.0	76.0	-2.0
Placebo		Week 6	80.0	82.0	-2.0
Placebo		Week 6	74.0	78.0	-4.0
Placebo		Week 8	74.0	76.0	-2.0
Placebo		Week 8	80.0	82.0	-2.0
Placebo		Week 8	78.0	78.0	0.0
Placebo			82.0	76.0
Placebo			80.0	82.0
Placebo			80.0	78.0
Placebo			78.0	76.0
Placebo			80.0	82.0
Placebo			78.0	78.0
Xanomeline Low Dose		Week 12	89.0	80.0	9.0
Xanomeline Low Dose		Week 12	76.0	84.0	-8.0
Xanomeline Low Dose		Week 12	79.0	86.0	-7.0
Xanomeline Low Dose		Week 16	66.0	80.0	-14.0
Xanomeline Low Dose		Week 16	72.0	84.0	-12.0
Xanomeline Low Dose		Week 16	76.0	86.0	-10.0
Xanomeline Low Dose		Week 2	72.0	80.0	-8.0
Xanomeline Low Dose		Week 2	80.0	84.0	-4.0
Xanomeline Low Dose		Week 2	77.0	86.0	-9.0
Xanomeline Low Dose		Week 20	70.0	80.0	-10.0
Xanomeline Low Dose		Week 20	77.0	84.0	-7.0
Xanomeline Low Dose		Week 20	80.0	86.0	-6.0
Xanomeline Low Dose		Week 24	56.0	80.0	-24.0
Xanomeline Low Dose		Week 24	74.0	84.0	-10.0
Xanomeline Low Dose		Week 24	72.0	86.0	-14.0
Xanomeline Low Dose		Week 26	66.0	80.0	-14.0
Xanomeline Low Dose		Week 26	72.0	84.0	-12.0
Xanomeline Low Dose		Week 26	75.0	86.0	-11.0
Xanomeline Low Dose		Week 4	70.0	80.0	-10.0
Xanomeline Low Dose		Week 4	75.0	84.0	-9.0
Xanomeline Low Dose		Week 4	73.0	86.0	-13.0
Xanomeline Low Dose		Week 6	80.0	80.0	0.0
Xanomeline Low Dose		Week 6	87.0	84.0	3.0
Xanomeline Low Dose		Week 6	90.0	86.0	4.0
Xanomeline Low Dose		Week 8	73.0	80.0	-7.0
Xanomeline Low Dose		Week 8	82.0	84.0	-2.0
Xanomeline Low Dose		Week 8	76.0	86.0	-10.0
Xanomeline Low Dose			86.0	80.0
Xanomeline Low Dose			98.0	84.0
Xanomeline Low Dose			100.0	86.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			75.0	84.0
Xanomeline Low Dose			77.0	86.0
Xanomeline Low Dose		Week 2	65.0	64.0	1.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	86.0	74.0	12.0
Xanomeline Low Dose		Week 4	58.0	64.0	-6.0
Xanomeline Low Dose		Week 4	71.0	72.0	-1.0
Xanomeline Low Dose		Week 4	80.0	74.0	6.0
Xanomeline Low Dose		Week 6	70.0	64.0	6.0
Xanomeline Low Dose		Week 6	85.0	72.0	13.0
Xanomeline Low Dose		Week 6	82.0	74.0	8.0
Xanomeline Low Dose		Week 8	76.0	64.0	12.0
Xanomeline Low Dose		Week 8	80.0	72.0	8.0
Xanomeline Low Dose		Week 8	87.0	74.0	13.0
Xanomeline Low Dose			73.0	64.0
Xanomeline Low Dose			81.0	72.0
Xanomeline Low Dose			91.0	74.0
Xanomeline Low Dose			77.0	64.0
Xanomeline Low Dose			98.0	72.0
Xanomeline Low Dose			86.0	74.0
Placebo		Week 2	83.0	65.0	18.0
Placebo		Week 2	90.0	67.0	23.0
Placebo		Week 2	95.0	74.0	21.0
Placebo		Week 4	74.0	65.0	9.0
Placebo		Week 4	77.0	67.0	10.0
Placebo		Week 4	80.0	74.0	6.0
Placebo			73.0	65.0
Placebo			85.0	67.0
Placebo			91.0	74.0
Placebo			66.0	65.0
Placebo			76.0	67.0
Placebo			80.0	74.0
Placebo		Week 12	80.0	81.0	-1.0
Placebo		Week 12	90.0	80.0	10.0
Placebo		Week 12	88.0	88.0	0.0
Placebo		Week 16	78.0	81.0	-3.0
Placebo		Week 16	77.0	80.0	-3.0
Placebo		Week 16	80.0	88.0	-8.0
Placebo		Week 2	66.0	81.0	-15.0
Placebo		Week 2	73.0	80.0	-7.0
Placebo		Week 2	83.0	88.0	-5.0
Placebo		Week 20	76.0	81.0	-5.0
Placebo		Week 20	85.0	80.0	5.0
Placebo		Week 20	80.0	88.0	-8.0
Placebo		Week 24	80.0	81.0	-1.0
Placebo		Week 24	83.0	80.0	3.0
Placebo		Week 24	86.0	88.0	-2.0
Placebo		Week 4	67.0	81.0	-14.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	77.0	88.0	-11.0
Placebo		Week 6	79.0	81.0	-2.0
Placebo		Week 6	85.0	80.0	5.0
Placebo		Week 6	82.0	88.0	-6.0
Placebo		Week 8	75.0	81.0	-6.0
Placebo		Week 8	79.0	80.0	-1.0
Placebo		Week 8	85.0	88.0	-3.0
Placebo			72.0	81.0
Placebo			80.0	80.0
Placebo			74.0	88.0
Placebo			72.0	81.0
Placebo			87.0	80.0
Placebo			82.0	88.0
Xanomeline High Dose		Week 2	67.0	67.0	0.0
Xanomeline High Dose		Week 2	89.0	79.0	10.0
Xanomeline High Dose		Week 2	91.0	83.0	8.0
Xanomeline High Dose			61.0	67.0
Xanomeline High Dose			111.0	79.0
Xanomeline High Dose			102.0	83.0
Xanomeline High Dose		Week 2	72.0	65.0	7.0
Xanomeline High Dose		Week 2	76.0	69.0	7.0
Xanomeline High Dose		Week 2	79.0	71.0	8.0
Xanomeline High Dose		Week 4	68.0	65.0	3.0
Xanomeline High Dose		Week 4	74.0	69.0	5.0
Xanomeline High Dose		Week 4	76.0	71.0	5.0
Xanomeline High Dose		Week 6	67.0	65.0	2.0
Xanomeline High Dose		Week 6	73.0	69.0	4.0
Xanomeline High Dose		Week 6	79.0	71.0	8.0
Xanomeline High Dose		Week 8	75.0	65.0	10.0
Xanomeline High Dose		Week 8	73.0	69.0	4.0
Xanomeline High Dose		Week 8	72.0	71.0	1.0
Xanomeline High Dose			69.0	65.0
Xanomeline High Dose			74.0	69.0
Xanomeline High Dose			76.0	71.0
Xanomeline High Dose			79.0	65.0
Xanomeline High Dose			80.0	69.0
Xanomeline High Dose			79.0	71.0
Placebo		Week 12	69.0	80.0	-11.0
Placebo		Week 12	72.0	82.0	-10.0
Placebo		Week 12	74.0	82.0	-8.0
Placebo		Week 16	63.0	80.0	-17.0
Placebo		Week 16	67.0	82.0	-15.0
Placebo		Week 16	67.0	82.0	-15.0
Placebo		Week 2	69.0	80.0	-11.0
Placebo		Week 2	76.0	82.0	-6.0
Placebo		Week 2	74.0	82.0	-8.0
Placebo		Week 20	63.0	80.0	-17.0
Placebo		Week 20	69.0	82.0	-13.0
Placebo		Week 20	70.0	82.0	-12.0
Placebo		Week 24	76.0	80.0	-4.0
Placebo		Week 24	83.0	82.0	1.0
Placebo		Week 24	84.0	82.0	2.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 4	68.0	82.0	-14.0
Placebo		Week 4	69.0	82.0	-13.0
Placebo		Week 6	69.0	80.0	-11.0
Placebo		Week 6	75.0	82.0	-7.0
Placebo		Week 6	75.0	82.0	-7.0
Placebo		Week 8	72.0	80.0	-8.0
Placebo		Week 8	75.0	82.0	-7.0
Placebo		Week 8	76.0	82.0	-6.0
Placebo			63.0	80.0
Placebo			65.0	82.0
Placebo			70.0	82.0
Placebo			61.0	80.0
Placebo			64.0	82.0
Placebo			66.0	82.0
Placebo		Week 12	72.0	64.0	8.0
Placebo		Week 12	72.0	68.0	4.0
Placebo		Week 12	72.0	68.0	4.0
Placebo		Week 16	70.0	64.0	6.0
Placebo		Week 16	76.0	68.0	8.0
Placebo		Week 16	76.0	68.0	8.0
Placebo		Week 2	64.0	64.0	0.0
Placebo		Week 2	72.0	68.0	4.0
Placebo		Week 2	60.0	68.0	-8.0
Placebo		Week 20	72.0	64.0	8.0
Placebo		Week 20	72.0	68.0	4.0
Placebo		Week 20	72.0	68.0	4.0
Placebo		Week 24	72.0	64.0	8.0
Placebo		Week 24	72.0	68.0	4.0
Placebo		Week 24	72.0	68.0	4.0
Placebo		Week 26	74.0	64.0	10.0
Placebo		Week 26	78.0	68.0	10.0
Placebo		Week 26	78.0	68.0	10.0
Placebo		Week 4	76.0	64.0	12.0
Placebo		Week 4	76.0	68.0	8.0
Placebo		Week 4	76.0	68.0	8.0
Placebo		Week 6	96.0	64.0	32.0
Placebo		Week 6	108.0	68.0	40.0
Placebo		Week 6	92.0	68.0	24.0
Placebo		Week 8	84.0	64.0	20.0
Placebo		Week 8	80.0	68.0	12.0
Placebo		Week 8	80.0	68.0	12.0
Placebo			70.0	64.0
Placebo			78.0	68.0
Placebo			76.0	68.0
Placebo			70.0	64.0
Placebo			70.0	68.0
Placebo			66.0	68.0
Placebo		Week 12	80.0	64.0	16.0
Placebo		Week 12	96.0	80.0	16.0
Placebo		Week 12	88.0	80.0	8.0
Placebo		Week 16	72.0	64.0	8.0
Placebo		Week 16	72.0	80.0	-8.0
Placebo		Week 16	72.0	80.0	-8.0
Placebo		Week 2	72.0	64.0	8.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 2	72.0	80.0	-8.0
Placebo		Week 20	72.0	64.0	8.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 20	72.0	80.0	-8.0
Placebo		Week 24	80.0	64.0	16.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 24	80.0	80.0	0.0
Placebo		Week 26	76.0	64.0	12.0
Placebo		Week 26	76.0	80.0	-4.0
Placebo		Week 26	76.0	80.0	-4.0
Placebo		Week 4	68.0	64.0	4.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 4	70.0	80.0	-10.0
Placebo		Week 6	68.0	64.0	4.0
Placebo		Week 6	68.0	80.0	-12.0
Placebo		Week 6	68.0	80.0	-12.0
Placebo		Week 8	70.0	64.0	6.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo		Week 8	70.0	80.0	-10.0
Placebo			78.0	64.0
Placebo			81.0	80.0
Placebo			81.0	80.0
Placebo			68.0	64.0
Placebo			70.0	80.0
Placebo			72.0	80.0
Placebo		Week 12	68.0	75.0	-7.0
Placebo		Week 12	72.0	84.0	-12.0
Placebo		Week 12	68.0	88.0	-20.0
Placebo		Week 16	70.0	75.0	-5.0
Placebo		Week 16	70.0	84.0	-14.0
Placebo		Week 16	70.0	88.0	-18.0
Placebo		Week 2	80.0	75.0	5.0
Placebo		Week 2	92.0	84.0	8.0
Placebo		Week 2	88.0	88.0	0.0
Placebo		Week 20	72.0	75.0	-3.0
Placebo		Week 20	72.0	84.0	-12.0
Placebo		Week 20	72.0	88.0	-16.0
Placebo		Week 24	66.0	75.0	-9.0
Placebo		Week 24	70.0	84.0	-14.0
Placebo		Week 24	74.0	88.0	-14.0
Placebo		Week 26	70.0	75.0	-5.0
Placebo		Week 26	70.0	84.0	-14.0
Placebo		Week 26	70.0	88.0	-18.0
Placebo		Week 4	64.0	75.0	-11.0
Placebo		Week 4	72.0	84.0	-12.0
Placebo		Week 4	76.0	88.0	-12.0
Placebo		Week 6	68.0	75.0	-7.0
Placebo		Week 6	68.0	84.0	-16.0
Placebo		Week 6	72.0	88.0	-16.0
Placebo		Week 8	76.0	75.0	1.0
Placebo		Week 8	76.0	84.0	-8.0
Placebo		Week 8	77.0	88.0	-11.0
Placebo			72.0	75.0
Placebo			84.0	84.0
Placebo			80.0	88.0
Placebo			96.0	75.0
Placebo			100.0	84.0
Placebo			100.0	88.0
Xanomeline Low Dose		Week 12	84.0	64.0	20.0
Xanomeline Low Dose		Week 12	88.0	72.0	16.0
Xanomeline Low Dose		Week 12	88.0	64.0	24.0
Xanomeline Low Dose		Week 2	68.0	64.0	4.0
Xanomeline Low Dose		Week 2	72.0	72.0	0.0
Xanomeline Low Dose		Week 2	80.0	64.0	16.0
Xanomeline Low Dose		Week 4	72.0	64.0	8.0
Xanomeline Low Dose		Week 4	76.0	72.0	4.0
Xanomeline Low Dose		Week 4	76.0	64.0	12.0
Xanomeline Low Dose		Week 6	60.0	64.0	-4.0
Xanomeline Low Dose		Week 6	80.0	72.0	8.0
Xanomeline Low Dose		Week 6	76.0	64.0	12.0
Xanomeline Low Dose		Week 8	52.0	64.0	-12.0
Xanomeline Low Dose		Week 8	60.0	72.0	-12.0
Xanomeline Low Dose		Week 8	64.0	64.0	0.0
Xanomeline Low Dose			80.0	64.0
Xanomeline Low Dose			88.0	72.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			68.0	64.0
Xanomeline Low Dose			72.0	72.0
Xanomeline Low Dose			72.0	64.0
Xanomeline High Dose		Week 2	88.0	66.0	22.0
Xanomeline High Dose		Week 2	88.0	80.0	8.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 4	84.0	66.0	18.0
Xanomeline High Dose		Week 4	86.0	80.0	6.0
Xanomeline High Dose		Week 4	86.0	80.0	6.0
Xanomeline High Dose		Week 6	88.0	66.0	22.0
Xanomeline High Dose		Week 6	88.0	80.0	8.0
Xanomeline High Dose		Week 6	80.0	80.0	0.0
Xanomeline High Dose		Week 8	62.0	66.0	-4.0
Xanomeline High Dose		Week 8	85.0	80.0	5.0
Xanomeline High Dose		Week 8	66.0	80.0	-14.0
Xanomeline High Dose			80.0	66.0
Xanomeline High Dose			88.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			75.0	66.0
Xanomeline High Dose			86.0	80.0
Xanomeline High Dose			84.0	80.0
Xanomeline Low Dose		Week 2	65.0	72.0	-7.0
Xanomeline Low Dose		Week 2	76.0	88.0	-12.0
Xanomeline Low Dose		Week 2	76.0	72.0	4.0
Xanomeline Low Dose		Week 4	76.0	72.0	4.0
Xanomeline Low Dose		Week 4	88.0	88.0	0.0
Xanomeline Low Dose		Week 4	84.0	72.0	12.0
Xanomeline Low Dose			80.0	72.0
Xanomeline Low Dose			88.0	88.0
Xanomeline Low Dose			84.0	72.0
Xanomeline Low Dose			60.0	72.0
Xanomeline Low Dose			76.0	88.0
Xanomeline Low Dose			68.0	72.0
Xanomeline Low Dose		Week 12	62.0	68.0	-6.0
Xanomeline Low Dose		Week 12	66.0	68.0	-2.0
Xanomeline Low Dose		Week 12	66.0	68.0	-2.0
Xanomeline Low Dose		Week 16	62.0	68.0	-6.0
Xanomeline Low Dose		Week 16	66.0	68.0	-2.0
Xanomeline Low Dose		Week 16	62.0	68.0	-6.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 20	60.0	68.0	-8.0
Xanomeline Low Dose		Week 20	62.0	68.0	-6.0
Xanomeline Low Dose		Week 20	62.0	68.0	-6.0
Xanomeline Low Dose		Week 24	68.0	68.0	0.0
Xanomeline Low Dose		Week 24	72.0	68.0	4.0
Xanomeline Low Dose		Week 24	72.0	68.0	4.0
Xanomeline Low Dose		Week 26	66.0	68.0	-2.0
Xanomeline Low Dose		Week 26	64.0	68.0	-4.0
Xanomeline Low Dose		Week 26	62.0	68.0	-6.0
Xanomeline Low Dose		Week 4	74.0	68.0	6.0
Xanomeline Low Dose		Week 4	74.0	68.0	6.0
Xanomeline Low Dose		Week 4	74.0	68.0	6.0
Xanomeline Low Dose		Week 6	64.0	68.0	-4.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	70.0	68.0	2.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			70.0	68.0
Xanomeline Low Dose			60.0	68.0
Xanomeline Low Dose			60.0	68.0
Xanomeline Low Dose			60.0	68.0
Placebo		Week 12	72.0	76.0	-4.0
Placebo		Week 12	76.0	76.0	0.0
Placebo		Week 12	80.0	84.0	-4.0
Placebo		Week 16	64.0	76.0	-12.0
Placebo		Week 16	72.0	76.0	-4.0
Placebo		Week 16	72.0	84.0	-12.0
Placebo		Week 2	64.0	76.0	-12.0
Placebo		Week 2	80.0	76.0	4.0
Placebo		Week 2	72.0	84.0	-12.0
Placebo		Week 20	74.0	76.0	-2.0
Placebo		Week 20	76.0	76.0	0.0
Placebo		Week 20	76.0	84.0	-8.0
Placebo		Week 24	78.0	76.0	2.0
Placebo		Week 24	82.0	76.0	6.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 26	68.0	76.0	-8.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 26	78.0	84.0	-6.0
Placebo		Week 4	68.0	76.0	-8.0
Placebo		Week 4	80.0	76.0	4.0
Placebo		Week 4	80.0	84.0	-4.0
Placebo		Week 6	76.0	76.0	0.0
Placebo		Week 6	86.0	76.0	10.0
Placebo		Week 6	86.0	84.0	2.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo		Week 8	72.0	76.0	-4.0
Placebo		Week 8	72.0	84.0	-12.0
Placebo			60.0	76.0
Placebo			70.0	76.0
Placebo			70.0	84.0
Placebo			64.0	76.0
Placebo			72.0	76.0
Placebo			76.0	84.0
Xanomeline Low Dose		Week 12	68.0	67.0	1.0
Xanomeline Low Dose		Week 12	68.0	80.0	-12.0
Xanomeline Low Dose		Week 12	68.0	76.0	-8.0
Xanomeline Low Dose		Week 2	76.0	67.0	9.0
Xanomeline Low Dose		Week 2	80.0	80.0	0.0
Xanomeline Low Dose		Week 2	88.0	76.0	12.0
Xanomeline Low Dose		Week 4	70.0	67.0	3.0
Xanomeline Low Dose		Week 4	70.0	80.0	-10.0
Xanomeline Low Dose		Week 4	70.0	76.0	-6.0
Xanomeline Low Dose		Week 6	68.0	67.0	1.0
Xanomeline Low Dose		Week 6	68.0	80.0	-12.0
Xanomeline Low Dose		Week 6	68.0	76.0	-8.0
Xanomeline Low Dose		Week 8	72.0	67.0	5.0
Xanomeline Low Dose		Week 8	72.0	80.0	-8.0
Xanomeline Low Dose		Week 8	72.0	76.0	-4.0
Xanomeline Low Dose			70.0	67.0
Xanomeline Low Dose			72.0	80.0
Xanomeline Low Dose			72.0	76.0
Xanomeline Low Dose			70.0	67.0
Xanomeline Low Dose			70.0	80.0
Xanomeline Low Dose			70.0	76.0
Xanomeline Low Dose		Week 12	70.0	50.0	20.0
Xanomeline Low Dose		Week 12	70.0	56.0	14.0
Xanomeline Low Dose		Week 12	70.0	52.0	18.0
Xanomeline Low Dose		Week 16	48.0	50.0	-2.0
Xanomeline Low Dose		Week 16	52.0	56.0	-4.0
Xanomeline Low Dose		Week 16	52.0	52.0	0.0
Xanomeline Low Dose		Week 2	54.0	50.0	4.0
Xanomeline Low Dose		Week 2	60.0	56.0	4.0
Xanomeline Low Dose		Week 2	52.0	52.0	0.0
Xanomeline Low Dose		Week 20	68.0	50.0	18.0
Xanomeline Low Dose		Week 20	68.0	56.0	12.0
Xanomeline Low Dose		Week 20	68.0	52.0	16.0
Xanomeline Low Dose		Week 24	52.0	50.0	2.0
Xanomeline Low Dose		Week 24	52.0	56.0	-4.0
Xanomeline Low Dose		Week 24	52.0	52.0	0.0
Xanomeline Low Dose		Week 4	48.0	50.0	-2.0
Xanomeline Low Dose		Week 4	64.0	56.0	8.0
Xanomeline Low Dose		Week 4	60.0	52.0	8.0
Xanomeline Low Dose		Week 6	52.0	50.0	2.0
Xanomeline Low Dose		Week 6	56.0	56.0	0.0
Xanomeline Low Dose		Week 6	56.0	52.0	4.0
Xanomeline Low Dose		Week 8	51.0	50.0	1.0
Xanomeline Low Dose		Week 8	68.0	56.0	12.0
Xanomeline Low Dose		Week 8	64.0	52.0	12.0
Xanomeline Low Dose			60.0	50.0
Xanomeline Low Dose			56.0	56.0
Xanomeline Low Dose			60.0	52.0
Xanomeline Low Dose			50.0	50.0
Xanomeline Low Dose			58.0	56.0
Xanomeline Low Dose			50.0	52.0
Placebo		Week 12	80.0	60.0	20.0
Placebo		Week 12	80.0	64.0	16.0
Placebo		Week 12	80.0	67.0	13.0
Placebo		Week 16	66.0	60.0	6.0
Placebo		Week 16	78.0	64.0	14.0
Placebo		Week 16	78.0	67.0	11.0
Placebo		Week 2	70.0	60.0	10.0
Placebo		Week 2	70.0	64.0	6.0
Placebo		Week 2	70.0	67.0	3.0
Placebo		Week 20	68.0	60.0	8.0
Placebo		Week 20	84.0	64.0	20.0
Placebo		Week 20	80.0	67.0	13.0
Placebo		Week 24	68.0	60.0	8.0
Placebo		Week 24	68.0	64.0	4.0
Placebo		Week 24	64.0	67.0	-3.0
Placebo		Week 26	78.0	60.0	18.0
Placebo		Week 26	80.0	64.0	16.0
Placebo		Week 26	80.0	67.0	13.0
Placebo		Week 4	70.0	60.0	10.0
Placebo		Week 4	70.0	64.0	6.0
Placebo		Week 4	70.0	67.0	3.0
Placebo		Week 6	64.0	60.0	4.0
Placebo		Week 6	84.0	64.0	20.0
Placebo		Week 6	76.0	67.0	9.0
Placebo		Week 8	68.0	60.0	8.0
Placebo		Week 8	76.0	64.0	12.0
Placebo		Week 8	72.0	67.0	5.0
Placebo			64.0	60.0
Placebo			68.0	64.0
Placebo			64.0	67.0
Placebo			68.0	60.0
Placebo			76.0	64.0
Placebo			76.0	67.0
Xanomeline Low Dose		Week 12	80.0	71.0	9.0
Xanomeline Low Dose		Week 12	84.0	84.0	0.0
Xanomeline Low Dose		Week 12	88.0	81.0	7.0
Xanomeline Low Dose		Week 16	80.0	71.0	9.0
Xanomeline Low Dose		Week 16	84.0	84.0	0.0
Xanomeline Low Dose		Week 16	84.0	81.0	3.0
Xanomeline Low Dose		Week 2	64.0	71.0	-7.0
Xanomeline Low Dose		Week 2	74.0	84.0	-10.0
Xanomeline Low Dose		Week 2	74.0	81.0	-7.0
Xanomeline Low Dose		Week 20	74.0	71.0	3.0
Xanomeline Low Dose		Week 20	78.0	84.0	-6.0
Xanomeline Low Dose		Week 20	88.0	81.0	7.0
Xanomeline Low Dose		Week 24	70.0	71.0	-1.0
Xanomeline Low Dose		Week 24	84.0	84.0	0.0
Xanomeline Low Dose		Week 24	84.0	81.0	3.0
Xanomeline Low Dose		Week 4	68.0	71.0	-3.0
Xanomeline Low Dose		Week 4	80.0	84.0	-4.0
Xanomeline Low Dose		Week 4	80.0	81.0	-1.0
Xanomeline Low Dose		Week 6	72.0	71.0	1.0
Xanomeline Low Dose		Week 6	74.0	84.0	-10.0
Xanomeline Low Dose		Week 6	74.0	81.0	-7.0
Xanomeline Low Dose		Week 8	68.0	71.0	-3.0
Xanomeline Low Dose		Week 8	70.0	84.0	-14.0
Xanomeline Low Dose		Week 8	70.0	81.0	-11.0
Xanomeline Low Dose			76.0	71.0
Xanomeline Low Dose			88.0	84.0
Xanomeline Low Dose			80.0	81.0
Xanomeline Low Dose			80.0	71.0
Xanomeline Low Dose			88.0	84.0
Xanomeline Low Dose			80.0	81.0
Placebo		Week 12	66.0	74.0	-8.0
Placebo		Week 12	70.0	70.0	0.0
Placebo		Week 12	72.0	84.0	-12.0
Placebo		Week 16	68.0	74.0	-6.0
Placebo		Week 16	76.0	70.0	6.0
Placebo		Week 16	80.0	84.0	-4.0
Placebo		Week 2	64.0	74.0	-10.0
Placebo		Week 2	76.0	70.0	6.0
Placebo		Week 2	78.0	84.0	-6.0
Placebo		Week 20	68.0	74.0	-6.0
Placebo		Week 20	66.0	70.0	-4.0
Placebo		Week 20	64.0	84.0	-20.0
Placebo		Week 24	64.0	74.0	-10.0
Placebo		Week 24	80.0	70.0	10.0
Placebo		Week 24	80.0	84.0	-4.0
Placebo		Week 26	60.0	74.0	-14.0
Placebo		Week 26	62.0	70.0	-8.0
Placebo		Week 26	66.0	84.0	-18.0
Placebo		Week 4	66.0	74.0	-8.0
Placebo		Week 4	78.0	70.0	8.0
Placebo		Week 4	80.0	84.0	-4.0
Placebo		Week 6	76.0	74.0	2.0
Placebo		Week 6	82.0	70.0	12.0
Placebo		Week 6	82.0	84.0	-2.0
Placebo		Week 8	82.0	74.0	8.0
Placebo		Week 8	82.0	70.0	12.0
Placebo		Week 8	82.0	84.0	-2.0
Xanomeline High Dose		Week 12	70.0	66.0	4.0
Xanomeline High Dose		Week 12	70.0	68.0	2.0
Xanomeline High Dose		Week 12	70.0	68.0	2.0
Xanomeline High Dose		Week 16	54.0	66.0	-12.0
Xanomeline High Dose		Week 16	60.0	68.0	-8.0
Xanomeline High Dose		Week 16	64.0	68.0	-4.0
Xanomeline High Dose		Week 2	63.0	66.0	-3.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 2	72.0	68.0	4.0
Xanomeline High Dose		Week 4	60.0	66.0	-6.0
Xanomeline High Dose		Week 4	64.0	68.0	-4.0
Xanomeline High Dose		Week 4	68.0	68.0	0.0
Xanomeline High Dose		Week 6	74.0	66.0	8.0
Xanomeline High Dose		Week 6	74.0	68.0	6.0
Xanomeline High Dose		Week 6	74.0	68.0	6.0
Xanomeline High Dose		Week 8	72.0	66.0	6.0
Xanomeline High Dose		Week 8	70.0	68.0	2.0
Xanomeline High Dose		Week 8	70.0	68.0	2.0
Xanomeline High Dose			69.0	66.0
Xanomeline High Dose			72.0	68.0
Xanomeline High Dose			72.0	68.0
Xanomeline High Dose			60.0	66.0
Xanomeline High Dose			64.0	68.0
Xanomeline High Dose			64.0	68.0
Xanomeline High Dose		Week 2	60.0	64.0	-4.0
Xanomeline High Dose		Week 2	64.0	64.0	0.0
Xanomeline High Dose		Week 2	68.0	60.0	8.0
Xanomeline High Dose		Week 4	72.0	64.0	8.0
Xanomeline High Dose		Week 4	68.0	64.0	4.0
Xanomeline High Dose		Week 4	68.0	60.0	8.0
Xanomeline High Dose			60.0	64.0
Xanomeline High Dose			65.0	64.0
Xanomeline High Dose			68.0	60.0
Xanomeline High Dose			60.0	64.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			64.0	60.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	68.0	66.0	2.0
Xanomeline Low Dose		Week 2	68.0	68.0	0.0
Xanomeline Low Dose		Week 4	68.0	68.0	0.0
Xanomeline Low Dose		Week 4	68.0	66.0	2.0
Xanomeline Low Dose		Week 4	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	76.0	68.0	8.0
Xanomeline Low Dose		Week 6	78.0	66.0	12.0
Xanomeline Low Dose		Week 6	78.0	68.0	10.0
Xanomeline Low Dose		Week 8	72.0	68.0	4.0
Xanomeline Low Dose		Week 8	84.0	66.0	18.0
Xanomeline Low Dose		Week 8	84.0	68.0	16.0
Placebo		Week 2	64.0	82.0	-18.0
Placebo		Week 2	64.0	82.0	-18.0
Placebo		Week 2	64.0	82.0	-18.0
Placebo		Week 4	72.0	82.0	-10.0
Placebo		Week 4	80.0	82.0	-2.0
Placebo		Week 4	80.0	82.0	-2.0
Placebo		Week 6	70.0	82.0	-12.0
Placebo		Week 6	74.0	82.0	-8.0
Placebo		Week 6	74.0	82.0	-8.0
Placebo			74.0	82.0
Placebo			74.0	82.0
Placebo			74.0	82.0
Placebo			72.0	82.0
Placebo			80.0	82.0
Placebo			80.0	82.0
Xanomeline Low Dose		Week 12	72.0	70.0	2.0
Xanomeline Low Dose		Week 12	74.0	70.0	4.0
Xanomeline Low Dose		Week 12	74.0	70.0	4.0
Xanomeline Low Dose		Week 16	88.0	70.0	18.0
Xanomeline Low Dose		Week 16	104.0	70.0	34.0
Xanomeline Low Dose		Week 16	92.0	70.0	22.0
Xanomeline Low Dose		Week 2	82.0	70.0	12.0
Xanomeline Low Dose		Week 2	84.0	70.0	14.0
Xanomeline Low Dose		Week 2	86.0	70.0	16.0
Xanomeline Low Dose		Week 4	68.0	70.0	-2.0
Xanomeline Low Dose		Week 4	74.0	70.0	4.0
Xanomeline Low Dose		Week 4	74.0	70.0	4.0
Xanomeline Low Dose		Week 6	72.0	70.0	2.0
Xanomeline Low Dose		Week 6	74.0	70.0	4.0
Xanomeline Low Dose		Week 6	74.0	70.0	4.0
Xanomeline Low Dose		Week 8	80.0	70.0	10.0
Xanomeline Low Dose		Week 8	82.0	70.0	12.0
Xanomeline Low Dose		Week 8	82.0	70.0	12.0
Xanomeline High Dose		Week 12	62.0	68.0	-6.0
Xanomeline High Dose		Week 12	64.0	72.0	-8.0
Xanomeline High Dose		Week 12	64.0	72.0	-8.0
Xanomeline High Dose		Week 16	54.0	68.0	-14.0
Xanomeline High Dose		Week 16	56.0	72.0	-16.0
Xanomeline High Dose		Week 16	58.0	72.0	-14.0
Xanomeline High Dose		Week 2	70.0	68.0	2.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 2	70.0	72.0	-2.0
Xanomeline High Dose		Week 20	60.0	68.0	-8.0
Xanomeline High Dose		Week 20	64.0	72.0	-8.0
Xanomeline High Dose		Week 20	60.0	72.0	-12.0
Xanomeline High Dose		Week 24	68.0	68.0	0.0
Xanomeline High Dose		Week 24	66.0	72.0	-6.0
Xanomeline High Dose		Week 24	66.0	72.0	-6.0
Xanomeline High Dose		Week 26	66.0	68.0	-2.0
Xanomeline High Dose		Week 26	76.0	72.0	4.0
Xanomeline High Dose		Week 26	76.0	72.0	4.0
Xanomeline High Dose		Week 4	72.0	68.0	4.0
Xanomeline High Dose		Week 4	76.0	72.0	4.0
Xanomeline High Dose		Week 4	76.0	72.0	4.0
Xanomeline High Dose		Week 6	74.0	68.0	6.0
Xanomeline High Dose		Week 6	78.0	72.0	6.0
Xanomeline High Dose		Week 6	78.0	72.0	6.0
Xanomeline High Dose		Week 8	60.0	68.0	-8.0
Xanomeline High Dose		Week 8	68.0	72.0	-4.0
Xanomeline High Dose		Week 8	68.0	72.0	-4.0
Xanomeline High Dose		Week 2	73.0	60.0	13.0
Xanomeline High Dose		Week 2	74.0	68.0	6.0
Xanomeline High Dose		Week 2	74.0	64.0	10.0
Xanomeline High Dose		Week 4	60.0	60.0	0.0
Xanomeline High Dose		Week 4	64.0	68.0	-4.0
Xanomeline High Dose		Week 4	68.0	64.0	4.0
Xanomeline High Dose		Week 6	70.0	60.0	10.0
Xanomeline High Dose		Week 6	68.0	68.0	0.0
Xanomeline High Dose		Week 6	70.0	64.0	6.0
Xanomeline High Dose		Week 8	62.0	60.0	2.0
Xanomeline High Dose		Week 8	64.0	68.0	-4.0
Xanomeline High Dose		Week 8	64.0	64.0	0.0
Xanomeline High Dose			74.0	60.0
Xanomeline High Dose			70.0	68.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose			64.0	60.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose		Week 12	72.0	73.0	-1.0
Xanomeline High Dose		Week 12	88.0	73.0	15.0
Xanomeline High Dose		Week 12	80.0	73.0	7.0
Xanomeline High Dose		Week 16	68.0	73.0	-5.0
Xanomeline High Dose		Week 16	82.0	73.0	9.0
Xanomeline High Dose		Week 16	82.0	73.0	9.0
Xanomeline High Dose		Week 2	68.0	73.0	-5.0
Xanomeline High Dose		Week 2	68.0	73.0	-5.0
Xanomeline High Dose		Week 2	68.0	73.0	-5.0
Xanomeline High Dose		Week 20	64.0	73.0	-9.0
Xanomeline High Dose		Week 20	72.0	73.0	-1.0
Xanomeline High Dose		Week 20	80.0	73.0	7.0
Xanomeline High Dose		Week 24	64.0	73.0	-9.0
Xanomeline High Dose		Week 24	62.0	73.0	-11.0
Xanomeline High Dose		Week 24	62.0	73.0	-11.0
Xanomeline High Dose		Week 26	68.0	73.0	-5.0
Xanomeline High Dose		Week 26	66.0	73.0	-7.0
Xanomeline High Dose		Week 26	66.0	73.0	-7.0
Xanomeline High Dose		Week 4	60.0	73.0	-13.0
Xanomeline High Dose		Week 4	68.0	73.0	-5.0
Xanomeline High Dose		Week 4	84.0	73.0	11.0
Xanomeline High Dose		Week 6	60.0	73.0	-13.0
Xanomeline High Dose		Week 6	64.0	73.0	-9.0
Xanomeline High Dose		Week 6	62.0	73.0	-11.0
Xanomeline High Dose		Week 8	78.0	73.0	5.0
Xanomeline High Dose		Week 8	78.0	73.0	5.0
Xanomeline High Dose		Week 8	80.0	73.0	7.0
Xanomeline High Dose			70.0	73.0
Xanomeline High Dose			70.0	73.0
Xanomeline High Dose			70.0	73.0
Placebo		Week 12	84.0	76.0	8.0
Placebo		Week 12	82.0	88.0	-6.0
Placebo		Week 12	82.0	88.0	-6.0
Placebo		Week 16	64.0	76.0	-12.0
Placebo		Week 16	66.0	88.0	-22.0
Placebo		Week 16	66.0	88.0	-22.0
Placebo		Week 2	70.0	76.0	-6.0
Placebo		Week 2	80.0	88.0	-8.0
Placebo		Week 2	80.0	88.0	-8.0
Placebo		Week 20	80.0	76.0	4.0
Placebo		Week 20	80.0	88.0	-8.0
Placebo		Week 20	84.0	88.0	-4.0
Placebo		Week 24	70.0	76.0	-6.0
Placebo		Week 24	74.0	88.0	-14.0
Placebo		Week 24	74.0	88.0	-14.0
Placebo		Week 26	70.0	76.0	-6.0
Placebo		Week 26	84.0	88.0	-4.0
Placebo		Week 26	80.0	88.0	-8.0
Placebo		Week 4	68.0	76.0	-8.0
Placebo		Week 4	68.0	88.0	-20.0
Placebo		Week 4	68.0	88.0	-20.0
Placebo		Week 6	64.0	76.0	-12.0
Placebo		Week 6	68.0	88.0	-20.0
Placebo		Week 6	68.0	88.0	-20.0
Placebo		Week 8	74.0	76.0	-2.0
Placebo		Week 8	74.0	88.0	-14.0
Placebo		Week 8	74.0	88.0	-14.0
Placebo			80.0	76.0
Placebo			88.0	88.0
Placebo			80.0	88.0
Placebo			70.0	76.0
Placebo			70.0	88.0
Placebo			70.0	88.0
Xanomeline High Dose		Week 12	63.0	68.0	-5.0
Xanomeline High Dose		Week 12	68.0	72.0	-4.0
Xanomeline High Dose		Week 12	72.0	72.0	0.0
Xanomeline High Dose		Week 16	68.0	68.0	0.0
Xanomeline High Dose		Week 16	72.0	72.0	0.0
Xanomeline High Dose		Week 16	72.0	72.0	0.0
Xanomeline High Dose		Week 2	76.0	68.0	8.0
Xanomeline High Dose		Week 2	80.0	72.0	8.0
Xanomeline High Dose		Week 2	80.0	72.0	8.0
Xanomeline High Dose		Week 20	82.0	68.0	14.0
Xanomeline High Dose		Week 20	84.0	72.0	12.0
Xanomeline High Dose		Week 20	84.0	72.0	12.0
Xanomeline High Dose		Week 24	60.0	68.0	-8.0
Xanomeline High Dose		Week 24	68.0	72.0	-4.0
Xanomeline High Dose		Week 24	68.0	72.0	-4.0
Xanomeline High Dose		Week 26	60.0	68.0	-8.0
Xanomeline High Dose		Week 26	68.0	72.0	-4.0
Xanomeline High Dose		Week 26	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	70.0	68.0	2.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 4	72.0	72.0	0.0
Xanomeline High Dose		Week 6	64.0	68.0	-4.0
Xanomeline High Dose		Week 6	76.0	72.0	4.0
Xanomeline High Dose		Week 6	70.0	72.0	-2.0
Xanomeline High Dose		Week 8	68.0	68.0	0.0
Xanomeline High Dose		Week 8	68.0	72.0	-4.0
Xanomeline High Dose		Week 8	68.0	72.0	-4.0
Xanomeline High Dose			81.0	68.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			80.0	72.0
Xanomeline High Dose			68.0	68.0
Xanomeline High Dose			68.0	72.0
Xanomeline High Dose			70.0	72.0
Xanomeline Low Dose		Week 12	58.0	72.0	-14.0
Xanomeline Low Dose		Week 12	64.0	78.0	-14.0
Xanomeline Low Dose		Week 12	66.0	72.0	-6.0
Xanomeline Low Dose		Week 16	52.0	72.0	-20.0
Xanomeline Low Dose		Week 16	60.0	78.0	-18.0
Xanomeline Low Dose		Week 16	58.0	72.0	-14.0
Xanomeline Low Dose		Week 2	80.0	72.0	8.0
Xanomeline Low Dose		Week 2	82.0	78.0	4.0
Xanomeline Low Dose		Week 2	78.0	72.0	6.0
Xanomeline Low Dose		Week 20	64.0	72.0	-8.0
Xanomeline Low Dose		Week 20	70.0	78.0	-8.0
Xanomeline Low Dose		Week 20	72.0	72.0	0.0
Xanomeline Low Dose		Week 24	59.0	72.0	-13.0
Xanomeline Low Dose		Week 24	60.0	78.0	-18.0
Xanomeline Low Dose		Week 24	60.0	72.0	-12.0
Xanomeline Low Dose		Week 26	60.0	72.0	-12.0
Xanomeline Low Dose		Week 26	64.0	78.0	-14.0
Xanomeline Low Dose		Week 26	64.0	72.0	-8.0
Xanomeline Low Dose		Week 4	72.0	72.0	0.0
Xanomeline Low Dose		Week 4	72.0	78.0	-6.0
Xanomeline Low Dose		Week 4	68.0	72.0	-4.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 6	72.0	78.0	-6.0
Xanomeline Low Dose		Week 6	72.0	72.0	0.0
Xanomeline Low Dose		Week 8	64.0	72.0	-8.0
Xanomeline Low Dose		Week 8	60.0	78.0	-18.0
Xanomeline Low Dose		Week 8	62.0	72.0	-10.0
Xanomeline Low Dose			60.0	72.0
Xanomeline Low Dose			72.0	78.0
Xanomeline Low Dose			64.0	72.0
Xanomeline Low Dose			76.0	72.0
Xanomeline Low Dose			70.0	78.0
Xanomeline Low Dose			72.0	72.0
Xanomeline High Dose		Week 12	60.0	66.0	-6.0
Xanomeline High Dose		Week 12	52.0	64.0	-12.0
Xanomeline High Dose		Week 12	56.0	62.0	-6.0
Xanomeline High Dose		Week 16	64.0	66.0	-2.0
Xanomeline High Dose		Week 16	68.0	64.0	4.0
Xanomeline High Dose		Week 16	70.0	62.0	8.0
Xanomeline High Dose		Week 2	68.0	66.0	2.0
Xanomeline High Dose		Week 2	59.0	64.0	-5.0
Xanomeline High Dose		Week 2	56.0	62.0	-6.0
Xanomeline High Dose		Week 20	68.0	66.0	2.0
Xanomeline High Dose		Week 20	64.0	64.0	0.0
Xanomeline High Dose		Week 20	66.0	62.0	4.0
Xanomeline High Dose		Week 24	70.0	66.0	4.0
Xanomeline High Dose		Week 24	72.0	64.0	8.0
Xanomeline High Dose		Week 24	60.0	62.0	-2.0
Xanomeline High Dose		Week 26	64.0	66.0	-2.0
Xanomeline High Dose		Week 26	60.0	64.0	-4.0
Xanomeline High Dose		Week 26	62.0	62.0	0.0
Xanomeline High Dose		Week 4	66.0	66.0	0.0
Xanomeline High Dose		Week 4	58.0	64.0	-6.0
Xanomeline High Dose		Week 4	60.0	62.0	-2.0
Xanomeline High Dose		Week 6	76.0	66.0	10.0
Xanomeline High Dose		Week 6	70.0	64.0	6.0
Xanomeline High Dose		Week 6	72.0	62.0	10.0
Xanomeline High Dose		Week 8	70.0	66.0	4.0
Xanomeline High Dose		Week 8	64.0	64.0	0.0
Xanomeline High Dose		Week 8	56.0	62.0	-6.0
Xanomeline High Dose			78.0	66.0
Xanomeline High Dose			72.0	64.0
Xanomeline High Dose			66.0	62.0
Xanomeline High Dose			68.0	66.0
Xanomeline High Dose			64.0	64.0
Xanomeline High Dose			60.0	62.0
Xanomeline High Dose		Week 12	56.0	66.0	-10.0
Xanomeline High Dose		Week 12	70.0	80.0	-10.0
Xanomeline High Dose		Week 12	70.0	78.0	-8.0
Xanomeline High Dose		Week 16	72.0	66.0	6.0
Xanomeline High Dose		Week 16	84.0	80.0	4.0
Xanomeline High Dose		Week 16	82.0	78.0	4.0
Xanomeline High Dose		Week 2	86.0	66.0	20.0
Xanomeline High Dose		Week 2	90.0	80.0	10.0
Xanomeline High Dose		Week 2	90.0	78.0	12.0
Xanomeline High Dose		Week 20	84.0	66.0	18.0
Xanomeline High Dose		Week 20	86.0	80.0	6.0
Xanomeline High Dose		Week 20	92.0	78.0	14.0
Xanomeline High Dose		Week 24	64.0	66.0	-2.0
Xanomeline High Dose		Week 24	64.0	80.0	-16.0
Xanomeline High Dose		Week 24	68.0	78.0	-10.0
Xanomeline High Dose		Week 26	90.0	66.0	24.0
Xanomeline High Dose		Week 26	100.0	80.0	20.0
Xanomeline High Dose		Week 26	100.0	78.0	22.0
Xanomeline High Dose		Week 4	86.0	66.0	20.0
Xanomeline High Dose		Week 4	96.0	80.0	16.0
Xanomeline High Dose		Week 4	86.0	78.0	8.0
Xanomeline High Dose		Week 6	90.0	66.0	24.0
Xanomeline High Dose		Week 6	85.0	80.0	5.0
Xanomeline High Dose		Week 6	90.0	78.0	12.0
Xanomeline High Dose		Week 8	80.0	66.0	14.0
Xanomeline High Dose		Week 8	90.0	80.0	10.0
Xanomeline High Dose		Week 8	88.0	78.0	10.0
Xanomeline High Dose			80.0	66.0
Xanomeline High Dose			84.0	80.0
Xanomeline High Dose			88.0	78.0
Placebo		Week 2	68.0	60.0	8.0
Placebo		Week 2	72.0	64.0	8.0
Placebo		Week 2	74.0	64.0	10.0
Placebo		Week 4	60.0	60.0	0.0
Placebo		Week 4	62.0	64.0	-2.0
Placebo		Week 4	62.0	64.0	-2.0
Placebo		Week 6	60.0	60.0	0.0
Placebo		Week 6	62.0	64.0	-2.0
Placebo		Week 6	62.0	64.0	-2.0
Placebo		Week 8	66.0	60.0	6.0
Placebo		Week 8	82.0	64.0	18.0
Placebo		Week 8	76.0	64.0	12.0
Placebo			64.0	60.0
Placebo			70.0	64.0
Placebo			72.0	64.0
Placebo			62.0	60.0
Placebo			68.0	64.0
Placebo			70.0	64.0
Placebo		Week 2	84.0	84.0	0.0
Placebo		Week 2	90.0	96.0	-6.0
Placebo		Week 2	90.0	90.0	0.0
Placebo		Week 4	90.0	84.0	6.0
Placebo		Week 4	96.0	96.0	0.0
Placebo		Week 4	92.0	90.0	2.0
Placebo		Week 6	90.0	84.0	6.0
Placebo		Week 6	86.0	96.0	-10.0
Placebo		Week 6	90.0	90.0	0.0
Placebo		Week 8	88.0	84.0	4.0
Placebo		Week 8	96.0	96.0	0.0
Placebo		Week 8	98.0	90.0	8.0
Placebo			90.0	84.0
Placebo			84.0	96.0
Placebo			90.0	90.0
Placebo			84.0	84.0
Placebo			90.0	96.0
Placebo			96.0	90.0
Xanomeline High Dose		Week 12	54.0	52.0	2.0
Xanomeline High Dose		Week 12	50.0	58.0	-8.0
Xanomeline High Dose		Week 12	56.0	54.0	2.0
Xanomeline High Dose		Week 16	72.0	52.0	20.0
Xanomeline High Dose		Week 16	76.0	58.0	18.0
Xanomeline High Dose		Week 16	68.0	54.0	14.0
Xanomeline High Dose		Week 2	68.0	52.0	16.0
Xanomeline High Dose		Week 2	70.0	58.0	12.0
Xanomeline High Dose		Week 2	74.0	54.0	20.0
Xanomeline High Dose		Week 20	60.0	52.0	8.0
Xanomeline High Dose		Week 20	71.0	58.0	13.0
Xanomeline High Dose		Week 20	68.0	54.0	14.0
Xanomeline High Dose		Week 4	68.0	52.0	16.0
Xanomeline High Dose		Week 4	66.0	58.0	8.0
Xanomeline High Dose		Week 4	68.0	54.0	14.0
Xanomeline High Dose		Week 6	66.0	52.0	14.0
Xanomeline High Dose		Week 6	54.0	58.0	-4.0
Xanomeline High Dose		Week 6	64.0	54.0	10.0
Xanomeline High Dose		Week 8	50.0	52.0	-2.0
Xanomeline High Dose		Week 8	60.0	58.0	2.0
Xanomeline High Dose		Week 8	68.0	54.0	14.0
Xanomeline Low Dose		Week 12	60.0	60.0	0.0
Xanomeline Low Dose		Week 12	74.0	62.0	12.0
Xanomeline Low Dose		Week 12	75.0	64.0	11.0
Xanomeline Low Dose		Week 16	58.0	60.0	-2.0
Xanomeline Low Dose		Week 16	62.0	62.0	0.0
Xanomeline Low Dose		Week 16	64.0	64.0	0.0
Xanomeline Low Dose		Week 2	68.0	60.0	8.0
Xanomeline Low Dose		Week 2	80.0	62.0	18.0
Xanomeline Low Dose		Week 2	78.0	64.0	14.0
Xanomeline Low Dose		Week 20	60.0	60.0	0.0
Xanomeline Low Dose		Week 20	64.0	62.0	2.0
Xanomeline Low Dose		Week 20	64.0	64.0	0.0
Xanomeline Low Dose		Week 24	68.0	60.0	8.0
Xanomeline Low Dose		Week 24	74.0	62.0	12.0
Xanomeline Low Dose		Week 24	72.0	64.0	8.0
Xanomeline Low Dose		Week 4	56.0	60.0	-4.0
Xanomeline Low Dose		Week 4	60.0	62.0	-2.0
Xanomeline Low Dose		Week 4	64.0	64.0	0.0
Xanomeline Low Dose		Week 6	60.0	60.0	0.0
Xanomeline Low Dose		Week 6	62.0	62.0	0.0
Xanomeline Low Dose		Week 6	62.0	64.0	-2.0
Xanomeline Low Dose		Week 8	66.0	60.0	6.0
Xanomeline Low Dose		Week 8	78.0	62.0	16.0
Xanomeline Low Dose		Week 8	84.0	64.0	20.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			62.0	62.0
Xanomeline Low Dose			60.0	64.0
Xanomeline Low Dose			64.0	60.0
Xanomeline Low Dose			74.0	62.0
Xanomeline Low Dose			72.0	64.0
Xanomeline Low Dose		Week 2	84.0	81.0	3.0
Xanomeline Low Dose		Week 2	93.0	94.0	-1.0
Xanomeline Low Dose		Week 2	89.0	87.0	2.0
Xanomeline Low Dose		Week 4	76.0	81.0	-5.0
Xanomeline Low Dose		Week 4	76.0	94.0	-18.0
Xanomeline Low Dose		Week 4	86.0	87.0	-1.0
Xanomeline Low Dose			77.0	81.0
Xanomeline Low Dose			80.0	94.0
Xanomeline Low Dose			82.0	87.0
Xanomeline Low Dose			80.0	81.0
Xanomeline Low Dose			81.0	94.0
Xanomeline Low Dose			86.0	87.0
Xanomeline High Dose		Week 12	68.0	65.0	3.0
Xanomeline High Dose		Week 12	72.0	69.0	3.0
Xanomeline High Dose		Week 12	73.0	70.0	3.0
Xanomeline High Dose		Week 16	61.0	65.0	-4.0
Xanomeline High Dose		Week 16	78.0	69.0	9.0
Xanomeline High Dose		Week 16	75.0	70.0	5.0
Xanomeline High Dose		Week 2	59.0	65.0	-6.0
Xanomeline High Dose		Week 2	72.0	69.0	3.0
Xanomeline High Dose		Week 2	72.0	70.0	2.0
Xanomeline High Dose		Week 20	78.0	65.0	13.0
Xanomeline High Dose		Week 20	89.0	69.0	20.0
Xanomeline High Dose		Week 20	87.0	70.0	17.0
Xanomeline High Dose		Week 4	68.0	65.0	3.0
Xanomeline High Dose		Week 4	83.0	69.0	14.0
Xanomeline High Dose		Week 4	77.0	70.0	7.0
Xanomeline High Dose		Week 6	74.0	65.0	9.0
Xanomeline High Dose		Week 6	87.0	69.0	18.0
Xanomeline High Dose		Week 6	88.0	70.0	18.0
Xanomeline High Dose		Week 8	58.0	65.0	-7.0
Xanomeline High Dose		Week 8	78.0	69.0	9.0
Xanomeline High Dose		Week 8	74.0	70.0	4.0
Xanomeline High Dose			56.0	65.0
Xanomeline High Dose			71.0	69.0
Xanomeline High Dose			69.0	70.0
Xanomeline High Dose			62.0	65.0
Xanomeline High Dose			80.0	69.0
Xanomeline High Dose			79.0	70.0
Placebo		Week 12	57.0	67.0	-10.0
Placebo		Week 12	68.0	72.0	-4.0
Placebo		Week 12	64.0	72.0	-8.0
Placebo		Week 16	55.0	67.0	-12.0
Placebo		Week 16	71.0	72.0	-1.0
Placebo		Week 16	64.0	72.0	-8.0
Placebo		Week 2	64.0	67.0	-3.0
Placebo		Week 2	72.0	72.0	0.0
Placebo		Week 2	71.0	72.0	-1.0
Placebo		Week 20	61.0	67.0	-6.0
Placebo		Week 20	69.0	72.0	-3.0
Placebo		Week 20	68.0	72.0	-4.0
Placebo		Week 24	58.0	67.0	-9.0
Placebo		Week 24	68.0	72.0	-4.0
Placebo		Week 24	65.0	72.0	-7.0
Placebo		Week 26	56.0	67.0	-11.0
Placebo		Week 26	58.0	72.0	-14.0
Placebo		Week 26	64.0	72.0	-8.0
Placebo		Week 4	64.0	67.0	-3.0
Placebo		Week 4	74.0	72.0	2.0
Placebo		Week 4	72.0	72.0	0.0
Placebo		Week 6	62.0	67.0	-5.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	68.0	72.0	-4.0
Placebo		Week 8	62.0	67.0	-5.0
Placebo		Week 8	72.0	72.0	0.0
Placebo		Week 8	69.0	72.0	-3.0
Placebo			61.0	67.0
Placebo			71.0	72.0
Placebo			70.0	72.0
Placebo			66.0	67.0
Placebo			74.0	72.0
Placebo			70.0	72.0
Placebo		Week 12	66.0	60.0	6.0
Placebo		Week 12	70.0	57.0	13.0
Placebo		Week 12	68.0	55.0	13.0
Placebo		Week 16	61.0	60.0	1.0
Placebo		Week 16	61.0	57.0	4.0
Placebo		Week 16	62.0	55.0	7.0
Placebo		Week 2	67.0	60.0	7.0
Placebo		Week 2	63.0	57.0	6.0
Placebo		Week 2	66.0	55.0	11.0
Placebo		Week 20	64.0	60.0	4.0
Placebo		Week 20	70.0	57.0	13.0
Placebo		Week 20	67.0	55.0	12.0
Placebo		Week 24	62.0	60.0	2.0
Placebo		Week 24	58.0	57.0	1.0
Placebo		Week 24	60.0	55.0	5.0
Placebo		Week 4	57.0	60.0	-3.0
Placebo		Week 4	60.0	57.0	3.0
Placebo		Week 4	62.0	55.0	7.0
Placebo		Week 6	67.0	60.0	7.0
Placebo		Week 6	62.0	57.0	5.0
Placebo		Week 6	59.0	55.0	4.0
Placebo		Week 8	80.0	60.0	20.0
Placebo		Week 8	68.0	57.0	11.0
Placebo		Week 8	72.0	55.0	17.0
Placebo			60.0	60.0
Placebo			60.0	57.0
Placebo			56.0	55.0
Placebo			68.0	60.0
Placebo			64.0	57.0
Placebo			60.0	55.0
Xanomeline Low Dose		Week 2	68.0	74.0	-6.0
Xanomeline Low Dose		Week 2	76.0	91.0	-15.0
Xanomeline Low Dose		Week 2	80.0	90.0	-10.0
Xanomeline Low Dose			80.0	74.0
Xanomeline Low Dose			96.0	91.0
Xanomeline Low Dose			80.0	90.0
Placebo		Week 12	59.0	65.0	-6.0
Placebo		Week 12	62.0	72.0	-10.0
Placebo		Week 12	59.0	67.0	-8.0
Placebo		Week 2	68.0	65.0	3.0
Placebo		Week 2	76.0	72.0	4.0
Placebo		Week 2	64.0	67.0	-3.0
Placebo		Week 4	67.0	65.0	2.0
Placebo		Week 4	73.0	72.0	1.0
Placebo		Week 4	71.0	67.0	4.0
Placebo		Week 6	68.0	65.0	3.0
Placebo		Week 6	72.0	72.0	0.0
Placebo		Week 6	74.0	67.0	7.0
Placebo		Week 8	67.0	65.0	2.0
Placebo		Week 8	69.0	72.0	-3.0
Placebo		Week 8	70.0	67.0	3.0
Placebo			60.0	65.0
Placebo			66.0	72.0
Placebo			62.0	67.0
Placebo			65.0	65.0
Placebo			68.0	72.0
Placebo			70.0	67.0
Xanomeline Low Dose		Week 12	59.0	60.0	-1.0
Xanomeline Low Dose		Week 12	86.0	71.0	15.0
Xanomeline Low Dose		Week 12	70.0	64.0	6.0
Xanomeline Low Dose		Week 16	57.0	60.0	-3.0
Xanomeline Low Dose		Week 16	72.0	71.0	1.0
Xanomeline Low Dose		Week 16	69.0	64.0	5.0
Xanomeline Low Dose		Week 2	63.0	60.0	3.0
Xanomeline Low Dose		Week 2	70.0	71.0	-1.0
Xanomeline Low Dose		Week 2	70.0	64.0	6.0
Xanomeline Low Dose		Week 4	61.0	60.0	1.0
Xanomeline Low Dose		Week 4	72.0	71.0	1.0
Xanomeline Low Dose		Week 4	70.0	64.0	6.0
Xanomeline Low Dose		Week 6	61.0	60.0	1.0
Xanomeline Low Dose		Week 6	80.0	71.0	9.0
Xanomeline Low Dose		Week 6	69.0	64.0	5.0
Xanomeline Low Dose		Week 8	63.0	60.0	3.0
Xanomeline Low Dose		Week 8	73.0	71.0	2.0
Xanomeline Low Dose		Week 8	72.0	64.0	8.0
Xanomeline Low Dose			72.0	60.0
Xanomeline Low Dose			72.0	71.0
Xanomeline Low Dose			76.0	64.0
Xanomeline Low Dose			59.0	60.0
Xanomeline Low Dose			82.0	71.0
Xanomeline Low Dose			81.0	64.0
Xanomeline Low Dose		Week 12	78.0	51.0	27.0
Xanomeline Low Dose		Week 12	78.0	53.0	25.0
Xanomeline Low Dose		Week 12	76.0	51.0	25.0
Xanomeline Low Dose		Week 16	52.0	51.0	1.0
Xanomeline Low Dose		Week 16	58.0	53.0	5.0
Xanomeline Low Dose		Week 16	58.0	51.0	7.0
Xanomeline Low Dose		Week 2	54.0	51.0	3.0
Xanomeline Low Dose		Week 2	57.0	53.0	4.0
Xanomeline Low Dose		Week 2	55.0	51.0	4.0
Xanomeline Low Dose		Week 20	53.0	51.0	2.0
Xanomeline Low Dose		Week 20	55.0	53.0	2.0
Xanomeline Low Dose		Week 20	60.0	51.0	9.0
Xanomeline Low Dose		Week 24	76.0	51.0	25.0
Xanomeline Low Dose		Week 24	58.0	53.0	5.0
Xanomeline Low Dose		Week 24	56.0	51.0	5.0
Xanomeline Low Dose		Week 26	55.0	51.0	4.0
Xanomeline Low Dose		Week 26	55.0	53.0	2.0
Xanomeline Low Dose		Week 26	53.0	51.0	2.0
Xanomeline Low Dose		Week 4	52.0	51.0	1.0
Xanomeline Low Dose		Week 4	55.0	53.0	2.0
Xanomeline Low Dose		Week 4	52.0	51.0	1.0
Xanomeline Low Dose		Week 6	52.0	51.0	1.0
Xanomeline Low Dose		Week 6	59.0	53.0	6.0
Xanomeline Low Dose		Week 6	57.0	51.0	6.0
Xanomeline Low Dose		Week 8	49.0	51.0	-2.0
Xanomeline Low Dose		Week 8	51.0	53.0	-2.0
Xanomeline Low Dose		Week 8	54.0	51.0	3.0
Xanomeline Low Dose			56.0	51.0
Xanomeline Low Dose			60.0	53.0
Xanomeline Low Dose			64.0	51.0
Xanomeline Low Dose			55.0	51.0
Xanomeline Low Dose			62.0	53.0
Xanomeline Low Dose			57.0	51.0
Xanomeline High Dose		Week 2	68.0	66.0	2.0
Xanomeline High Dose		Week 2	80.0	72.0	8.0
Xanomeline High Dose		Week 2	68.0	72.0	-4.0
Xanomeline High Dose		Week 4	61.0	66.0	-5.0
Xanomeline High Dose		Week 4	66.0	72.0	-6.0
Xanomeline High Dose		Week 4	65.0	72.0	-7.0
Xanomeline High Dose		Week 6	67.0	66.0	1.0
Xanomeline High Dose		Week 6	74.0	72.0	2.0
Xanomeline High Dose		Week 6	72.0	72.0	0.0
Xanomeline High Dose		Week 8	62.0	66.0	-4.0
Xanomeline High Dose		Week 8	72.0	72.0	0.0
Xanomeline High Dose		Week 8	66.0	72.0	-6.0
Xanomeline High Dose			67.0	66.0
Xanomeline High Dose			70.0	72.0
Xanomeline High Dose			69.0	72.0
Placebo		Week 12	69.0	71.0	-2.0
Placebo		Week 12	83.0	80.0	3.0
Placebo		Week 12	77.0	76.0	1.0
Placebo		Week 16	81.0	71.0	10.0
Placebo		Week 16	82.0	80.0	2.0
Placebo		Week 16	77.0	76.0	1.0
Placebo		Week 2	77.0	71.0	6.0
Placebo		Week 2	79.0	80.0	-1.0
Placebo		Week 2	74.0	76.0	-2.0
Placebo		Week 20	83.0	71.0	12.0
Placebo		Week 20	95.0	80.0	15.0
Placebo		Week 20	76.0	76.0	0.0
Placebo		Week 24	86.0	71.0	15.0
Placebo		Week 24	88.0	80.0	8.0
Placebo		Week 24	83.0	76.0	7.0
Placebo		Week 26	65.0	71.0	-6.0
Placebo		Week 26	74.0	80.0	-6.0
Placebo		Week 26	76.0	76.0	0.0
Placebo		Week 4	65.0	71.0	-6.0
Placebo		Week 4	80.0	80.0	0.0
Placebo		Week 4	76.0	76.0	0.0
Placebo		Week 6	77.0	71.0	6.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 6	88.0	76.0	12.0
Placebo		Week 8	64.0	71.0	-7.0
Placebo		Week 8	80.0	80.0	0.0
Placebo		Week 8	81.0	76.0	5.0
Placebo			68.0	71.0
Placebo			72.0	80.0
Placebo			80.0	76.0
Placebo			84.0	71.0
Placebo			80.0	80.0
Placebo			80.0	76.0
Xanomeline High Dose		Week 2	80.0	74.0	6.0
Xanomeline High Dose		Week 2	78.0	84.0	-6.0
Xanomeline High Dose		Week 2	81.0	90.0	-9.0
Xanomeline High Dose		Week 4	99.0	74.0	25.0
Xanomeline High Dose		Week 4	91.0	84.0	7.0
Xanomeline High Dose		Week 4	97.0	90.0	7.0
Xanomeline High Dose		Week 6	65.0	74.0	-9.0
Xanomeline High Dose		Week 6	71.0	84.0	-13.0
Xanomeline High Dose		Week 6	72.0	90.0	-18.0
Xanomeline High Dose		Week 8	72.0	74.0	-2.0
Xanomeline High Dose		Week 8	81.0	84.0	-3.0
Xanomeline High Dose		Week 8	83.0	90.0	-7.0
Xanomeline High Dose			80.0	74.0
Xanomeline High Dose			89.0	84.0
Xanomeline High Dose			85.0	90.0
Xanomeline High Dose			97.0	90.0
Xanomeline High Dose		Week 2	66.0	65.0	1.0
Xanomeline High Dose		Week 2	86.0	70.0	16.0
Xanomeline High Dose		Week 2	83.0	67.0	16.0
Xanomeline High Dose		Week 4	66.0	65.0	1.0
Xanomeline High Dose		Week 4	69.0	70.0	-1.0
Xanomeline High Dose		Week 4	73.0	67.0	6.0
Xanomeline High Dose		Week 6	61.0	65.0	-4.0
Xanomeline High Dose		Week 6	70.0	70.0	0.0
Xanomeline High Dose		Week 6	62.0	67.0	-5.0
Xanomeline High Dose			64.0	65.0
Xanomeline High Dose			83.0	70.0
Xanomeline High Dose			77.0	67.0
Xanomeline High Dose			62.0	65.0
Xanomeline High Dose			77.0	70.0
Xanomeline High Dose			74.0	67.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

SYSBP

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	139.0	130.0	9.0
Placebo		Week 12	146.0	121.0	25.0
Placebo		Week 12	138.0	131.0	7.0
Placebo		Week 16	163.0	130.0	33.0
Placebo		Week 16	145.0	121.0	24.0
Placebo		Week 16	152.0	131.0	21.0
Placebo		Week 2	114.0	130.0	-16.0
Placebo		Week 2	121.0	121.0	0.0
Placebo		Week 2	132.0	131.0	1.0
Placebo		Week 20	137.0	130.0	7.0
Placebo		Week 20	139.0	121.0	18.0
Placebo		Week 20	136.0	131.0	5.0
Placebo		Week 24	129.0	130.0	-1.0
Placebo		Week 24	131.0	121.0	10.0
Placebo		Week 24	137.0	131.0	6.0
Placebo		Week 26	127.0	130.0	-3.0
Placebo		Week 26	128.0	121.0	7.0
Placebo		Week 26	129.0	131.0	-2.0
Placebo		Week 4	138.0	130.0	8.0
Placebo		Week 4	137.0	121.0	16.0
Placebo		Week 4	132.0	131.0	1.0
Placebo		Week 6	148.0	130.0	18.0
Placebo		Week 6	137.0	121.0	16.0
Placebo		Week 6	138.0	131.0	7.0
Placebo		Week 8	138.0	130.0	8.0
Placebo		Week 8	146.0	121.0	25.0
Placebo		Week 8	140.0	131.0	9.0
Placebo			137.0	130.0
Placebo			127.0	121.0
Placebo			146.0	131.0
Placebo			138.0	130.0
Placebo			131.0	121.0
Placebo			123.0	131.0
Placebo		Week 2	122.0	130.0	-8.0
Placebo		Week 2	130.0	132.0	-2.0
Placebo		Week 2	138.0	132.0	6.0
Placebo			133.0	130.0
Placebo			130.0	132.0
Placebo			138.0	132.0
Xanomeline High Dose		Week 12	128.0	138.0	-10.0
Xanomeline High Dose		Week 12	137.0	145.0	-8.0
Xanomeline High Dose		Week 12	138.0	139.0	-1.0
Xanomeline High Dose		Week 16	122.0	138.0	-16.0
Xanomeline High Dose		Week 16	130.0	145.0	-15.0
Xanomeline High Dose		Week 16	132.0	139.0	-7.0
Xanomeline High Dose		Week 2	134.0	138.0	-4.0
Xanomeline High Dose		Week 2	138.0	145.0	-7.0
Xanomeline High Dose		Week 2	131.0	139.0	-8.0
Xanomeline High Dose		Week 20	129.0	138.0	-9.0
Xanomeline High Dose		Week 20	123.0	145.0	-22.0
Xanomeline High Dose		Week 20	131.0	139.0	-8.0
Xanomeline High Dose		Week 24	130.0	138.0	-8.0
Xanomeline High Dose		Week 24	133.0	145.0	-12.0
Xanomeline High Dose		Week 24	131.0	139.0	-8.0
Xanomeline High Dose		Week 26	131.0	138.0	-7.0
Xanomeline High Dose		Week 26	118.0	145.0	-27.0
Xanomeline High Dose		Week 26	131.0	139.0	-8.0
Xanomeline High Dose		Week 4	130.0	138.0	-8.0
Xanomeline High Dose		Week 4	130.0	145.0	-15.0
Xanomeline High Dose		Week 4	138.0	139.0	-1.0
Xanomeline High Dose		Week 6	131.0	138.0	-7.0
Xanomeline High Dose		Week 6	131.0	145.0	-14.0
Xanomeline High Dose		Week 6	132.0	139.0	-7.0
Xanomeline High Dose		Week 8	137.0	138.0	-1.0
Xanomeline High Dose		Week 8	146.0	145.0	1.0
Xanomeline High Dose		Week 8	130.0	139.0	-9.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			137.0	145.0
Xanomeline High Dose			145.0	139.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			138.0	145.0
Xanomeline High Dose			146.0	139.0
Xanomeline Low Dose			151.0	136.0
Xanomeline Low Dose			139.0	116.0
Xanomeline Low Dose			139.0	121.0
Xanomeline High Dose		Week 12	145.0	163.0	-18.0
Xanomeline High Dose		Week 12	150.0	177.0	-27.0
Xanomeline High Dose		Week 12	177.0	168.0	9.0
Xanomeline High Dose		Week 16	154.0	163.0	-9.0
Xanomeline High Dose		Week 16	183.0	177.0	6.0
Xanomeline High Dose		Week 16	186.0	168.0	18.0
Xanomeline High Dose		Week 2	183.0	163.0	20.0
Xanomeline High Dose		Week 2	191.0	177.0	14.0
Xanomeline High Dose		Week 2	161.0	168.0	-7.0
Xanomeline High Dose		Week 20	167.0	163.0	4.0
Xanomeline High Dose		Week 20	181.0	177.0	4.0
Xanomeline High Dose		Week 20	185.0	168.0	17.0
Xanomeline High Dose		Week 24	178.0	163.0	15.0
Xanomeline High Dose		Week 24	198.0	177.0	21.0
Xanomeline High Dose		Week 24	164.0	168.0	-4.0
Xanomeline High Dose		Week 26	154.0	163.0	-9.0
Xanomeline High Dose		Week 26	150.0	177.0	-27.0
Xanomeline High Dose		Week 26	179.0	168.0	11.0
Xanomeline High Dose		Week 4	165.0	163.0	2.0
Xanomeline High Dose		Week 4	170.0	177.0	-7.0
Xanomeline High Dose		Week 4	169.0	168.0	1.0
Xanomeline High Dose		Week 6	145.0	163.0	-18.0
Xanomeline High Dose		Week 6	174.0	177.0	-3.0
Xanomeline High Dose		Week 6	170.0	168.0	2.0
Xanomeline High Dose		Week 8	188.0	163.0	25.0
Xanomeline High Dose		Week 8	197.0	177.0	20.0
Xanomeline High Dose		Week 8	198.0	168.0	30.0
Xanomeline High Dose			140.0	163.0
Xanomeline High Dose			166.0	177.0
Xanomeline High Dose			159.0	168.0
Placebo		Week 2	145.0	151.0	-6.0
Placebo		Week 2	146.0	145.0	1.0
Placebo		Week 2	153.0	167.0	-14.0
Placebo			146.0	151.0
Placebo			137.0	145.0
Placebo			148.0	167.0
Xanomeline Low Dose		Week 12	121.0	128.0	-7.0
Xanomeline Low Dose		Week 12	132.0	130.0	2.0
Xanomeline Low Dose		Week 12	139.0	132.0	7.0
Xanomeline Low Dose		Week 16	132.0	128.0	4.0
Xanomeline Low Dose		Week 16	138.0	130.0	8.0
Xanomeline Low Dose		Week 16	139.0	132.0	7.0
Xanomeline Low Dose		Week 2	124.0	128.0	-4.0
Xanomeline Low Dose		Week 2	130.0	130.0	0.0
Xanomeline Low Dose		Week 2	132.0	132.0	0.0
Xanomeline Low Dose		Week 20	121.0	128.0	-7.0
Xanomeline Low Dose		Week 20	112.0	130.0	-18.0
Xanomeline Low Dose		Week 20	115.0	132.0	-17.0
Xanomeline Low Dose		Week 24	137.0	128.0	9.0
Xanomeline Low Dose		Week 24	131.0	130.0	1.0
Xanomeline Low Dose		Week 24	130.0	132.0	-2.0
Xanomeline Low Dose		Week 26	123.0	128.0	-5.0
Xanomeline Low Dose		Week 26	132.0	130.0	2.0
Xanomeline Low Dose		Week 26	131.0	132.0	-1.0
Xanomeline Low Dose		Week 4	137.0	128.0	9.0
Xanomeline Low Dose		Week 4	134.0	130.0	4.0
Xanomeline Low Dose		Week 4	137.0	132.0	5.0
Xanomeline Low Dose		Week 6	122.0	128.0	-6.0
Xanomeline Low Dose		Week 6	124.0	130.0	-6.0
Xanomeline Low Dose		Week 6	124.0	132.0	-8.0
Xanomeline Low Dose		Week 8	136.0	128.0	8.0
Xanomeline Low Dose		Week 8	130.0	130.0	0.0
Xanomeline Low Dose		Week 8	131.0	132.0	-1.0
Xanomeline Low Dose			121.0	128.0
Xanomeline Low Dose			144.0	130.0
Xanomeline Low Dose			130.0	132.0
Xanomeline Low Dose			132.0	128.0
Xanomeline Low Dose			132.0	130.0
Xanomeline Low Dose			138.0	132.0
Xanomeline Low Dose		Week 2	122.0	130.0	-8.0
Xanomeline Low Dose		Week 2	119.0	106.0	13.0
Xanomeline Low Dose		Week 2	100.0	110.0	-10.0
Xanomeline Low Dose		Week 4	115.0	130.0	-15.0
Xanomeline Low Dose		Week 4	98.0	106.0	-8.0
Xanomeline Low Dose		Week 4	95.0	110.0	-15.0
Xanomeline Low Dose		Week 6	131.0	130.0	1.0
Xanomeline Low Dose		Week 6	107.0	106.0	1.0
Xanomeline Low Dose		Week 6	104.0	110.0	-6.0
Xanomeline Low Dose		Week 8	123.0	130.0	-7.0
Xanomeline Low Dose		Week 8	113.0	106.0	7.0
Xanomeline Low Dose		Week 8	98.0	110.0	-12.0
Xanomeline Low Dose			144.0	130.0
Xanomeline Low Dose			120.0	106.0
Xanomeline Low Dose			116.0	110.0
Xanomeline Low Dose			122.0	130.0
Xanomeline Low Dose			96.0	106.0
Xanomeline Low Dose			99.0	110.0
Placebo		Week 12	123.0	137.0	-14.0
Placebo		Week 12	130.0	129.0	1.0
Placebo		Week 12	130.0	123.0	7.0
Placebo		Week 16	122.0	137.0	-15.0
Placebo		Week 16	122.0	129.0	-7.0
Placebo		Week 16	114.0	123.0	-9.0
Placebo		Week 2	129.0	137.0	-8.0
Placebo		Week 2	127.0	129.0	-2.0
Placebo		Week 2	131.0	123.0	8.0
Placebo		Week 20	136.0	137.0	-1.0
Placebo		Week 20	154.0	129.0	25.0
Placebo		Week 20	135.0	123.0	12.0
Placebo		Week 24	130.0	137.0	-7.0
Placebo		Week 24	107.0	129.0	-22.0
Placebo		Week 24	116.0	123.0	-7.0
Placebo		Week 26	121.0	137.0	-16.0
Placebo		Week 26	113.0	129.0	-16.0
Placebo		Week 26	122.0	123.0	-1.0
Placebo		Week 4	130.0	137.0	-7.0
Placebo		Week 4	114.0	129.0	-15.0
Placebo		Week 4	130.0	123.0	7.0
Placebo		Week 6	129.0	137.0	-8.0
Placebo		Week 6	122.0	129.0	-7.0
Placebo		Week 6	122.0	123.0	-1.0
Placebo		Week 8	126.0	137.0	-11.0
Placebo		Week 8	106.0	129.0	-23.0
Placebo		Week 8	131.0	123.0	8.0
Placebo			131.0	137.0
Placebo			126.0	129.0
Placebo			138.0	123.0
Placebo			130.0	137.0
Placebo			114.0	129.0
Placebo			122.0	123.0
Placebo		Week 12	114.0	122.0	-8.0
Placebo		Week 12	117.0	122.0	-5.0
Placebo		Week 12	122.0	130.0	-8.0
Placebo		Week 16	123.0	122.0	1.0
Placebo		Week 16	141.0	122.0	19.0
Placebo		Week 16	155.0	130.0	25.0
Placebo		Week 2	123.0	122.0	1.0
Placebo		Week 2	131.0	122.0	9.0
Placebo		Week 2	123.0	130.0	-7.0
Placebo		Week 20	114.0	122.0	-8.0
Placebo		Week 20	107.0	122.0	-15.0
Placebo		Week 20	130.0	130.0	0.0
Placebo		Week 24	124.0	122.0	2.0
Placebo		Week 24	124.0	122.0	2.0
Placebo		Week 24	139.0	130.0	9.0
Placebo		Week 26	140.0	122.0	18.0
Placebo		Week 26	130.0	122.0	8.0
Placebo		Week 26	155.0	130.0	25.0
Placebo		Week 4	100.0	122.0	-22.0
Placebo		Week 4	123.0	122.0	1.0
Placebo		Week 4	123.0	130.0	-7.0
Placebo		Week 6	123.0	122.0	1.0
Placebo		Week 6	121.0	122.0	-1.0
Placebo		Week 6	136.0	130.0	6.0
Placebo		Week 8	145.0	122.0	23.0
Placebo		Week 8	138.0	122.0	16.0
Placebo		Week 8	146.0	130.0	16.0
Placebo			145.0	122.0
Placebo			138.0	122.0
Placebo			131.0	130.0
Placebo			115.0	122.0
Placebo			115.0	122.0
Placebo			122.0	130.0
Xanomeline High Dose		Week 12	129.0	160.0	-31.0
Xanomeline High Dose		Week 12	145.0	138.0	7.0
Xanomeline High Dose		Week 12	146.0	154.0	-8.0
Xanomeline High Dose		Week 16	169.0	160.0	9.0
Xanomeline High Dose		Week 16	153.0	138.0	15.0
Xanomeline High Dose		Week 16	144.0	154.0	-10.0
Xanomeline High Dose		Week 2	169.0	160.0	9.0
Xanomeline High Dose		Week 2	137.0	138.0	-1.0
Xanomeline High Dose		Week 2	144.0	154.0	-10.0
Xanomeline High Dose		Week 20	159.0	160.0	-1.0
Xanomeline High Dose		Week 20	158.0	138.0	20.0
Xanomeline High Dose		Week 20	130.0	154.0	-24.0
Xanomeline High Dose		Week 24	147.0	160.0	-13.0
Xanomeline High Dose		Week 24	137.0	138.0	-1.0
Xanomeline High Dose		Week 24	138.0	154.0	-16.0
Xanomeline High Dose		Week 4	181.0	160.0	21.0
Xanomeline High Dose		Week 4	155.0	138.0	17.0
Xanomeline High Dose		Week 4	160.0	154.0	6.0
Xanomeline High Dose		Week 6	161.0	160.0	1.0
Xanomeline High Dose		Week 6	137.0	138.0	-1.0
Xanomeline High Dose		Week 6	137.0	154.0	-17.0
Xanomeline High Dose		Week 8	145.0	160.0	-15.0
Xanomeline High Dose		Week 8	154.0	138.0	16.0
Xanomeline High Dose		Week 8	146.0	154.0	-8.0
Xanomeline High Dose			137.0	160.0
Xanomeline High Dose			123.0	138.0
Xanomeline High Dose			124.0	154.0
Xanomeline High Dose			154.0	160.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			146.0	154.0
Xanomeline High Dose		Week 2	108.0	128.0	-20.0
Xanomeline High Dose		Week 2	104.0	124.0	-20.0
Xanomeline High Dose		Week 2	116.0	115.0	1.0
Xanomeline High Dose		Week 4	121.0	128.0	-7.0
Xanomeline High Dose		Week 4	129.0	124.0	5.0
Xanomeline High Dose		Week 4	122.0	115.0	7.0
Xanomeline High Dose			113.0	128.0
Xanomeline High Dose			136.0	124.0
Xanomeline High Dose			121.0	115.0
Xanomeline High Dose			108.0	128.0
Xanomeline High Dose			115.0	124.0
Xanomeline High Dose			122.0	115.0
Xanomeline High Dose		Week 12	114.0	116.0	-2.0
Xanomeline High Dose		Week 12	107.0	116.0	-9.0
Xanomeline High Dose		Week 12	108.0	122.0	-14.0
Xanomeline High Dose		Week 16	114.0	116.0	-2.0
Xanomeline High Dose		Week 16	107.0	116.0	-9.0
Xanomeline High Dose		Week 16	109.0	122.0	-13.0
Xanomeline High Dose		Week 2	122.0	116.0	6.0
Xanomeline High Dose		Week 2	113.0	116.0	-3.0
Xanomeline High Dose		Week 2	115.0	122.0	-7.0
Xanomeline High Dose		Week 20	116.0	116.0	0.0
Xanomeline High Dose		Week 20	105.0	116.0	-11.0
Xanomeline High Dose		Week 20	102.0	122.0	-20.0
Xanomeline High Dose		Week 24	101.0	116.0	-15.0
Xanomeline High Dose		Week 24	96.0	116.0	-20.0
Xanomeline High Dose		Week 24	100.0	122.0	-22.0
Xanomeline High Dose		Week 26	107.0	116.0	-9.0
Xanomeline High Dose		Week 26	99.0	116.0	-17.0
Xanomeline High Dose		Week 26	95.0	122.0	-27.0
Xanomeline High Dose		Week 4	115.0	116.0	-1.0
Xanomeline High Dose		Week 4	101.0	116.0	-15.0
Xanomeline High Dose		Week 4	95.0	122.0	-27.0
Xanomeline High Dose		Week 6	115.0	116.0	-1.0
Xanomeline High Dose		Week 6	106.0	116.0	-10.0
Xanomeline High Dose		Week 6	108.0	122.0	-14.0
Xanomeline High Dose		Week 8	122.0	116.0	6.0
Xanomeline High Dose		Week 8	110.0	116.0	-6.0
Xanomeline High Dose		Week 8	116.0	122.0	-6.0
Xanomeline High Dose			132.0	116.0
Xanomeline High Dose			108.0	116.0
Xanomeline High Dose			117.0	122.0
Xanomeline High Dose			123.0	116.0
Xanomeline High Dose			116.0	116.0
Xanomeline High Dose			118.0	122.0
Placebo		Week 12	161.0	142.0	19.0
Placebo		Week 12	140.0	137.0	3.0
Placebo		Week 12	145.0	138.0	7.0
Placebo		Week 16	150.0	142.0	8.0
Placebo		Week 16	145.0	137.0	8.0
Placebo		Week 16	154.0	138.0	16.0
Placebo		Week 2	142.0	142.0	0.0
Placebo		Week 2	154.0	137.0	17.0
Placebo		Week 2	141.0	138.0	3.0
Placebo		Week 20	144.0	142.0	2.0
Placebo		Week 20	138.0	137.0	1.0
Placebo		Week 20	138.0	138.0	0.0
Placebo		Week 24	153.0	142.0	11.0
Placebo		Week 24	140.0	137.0	3.0
Placebo		Week 24	145.0	138.0	7.0
Placebo		Week 4	138.0	142.0	-4.0
Placebo		Week 4	136.0	137.0	-1.0
Placebo		Week 4	138.0	138.0	0.0
Placebo		Week 6	145.0	142.0	3.0
Placebo		Week 6	151.0	137.0	14.0
Placebo		Week 6	154.0	138.0	16.0
Placebo		Week 8	144.0	142.0	2.0
Placebo		Week 8	139.0	137.0	2.0
Placebo		Week 8	138.0	138.0	0.0
Placebo			146.0	142.0
Placebo			138.0	137.0
Placebo			146.0	138.0
Placebo			145.0	142.0
Placebo			122.0	137.0
Placebo			132.0	138.0
Xanomeline High Dose		Week 2	138.0	132.0	6.0
Xanomeline High Dose		Week 2	126.0	130.0	-4.0
Xanomeline High Dose		Week 2	134.0	130.0	4.0
Xanomeline High Dose		Week 4	124.0	132.0	-8.0
Xanomeline High Dose		Week 4	115.0	130.0	-15.0
Xanomeline High Dose		Week 4	129.0	130.0	-1.0
Xanomeline High Dose			144.0	132.0
Xanomeline High Dose			131.0	130.0
Xanomeline High Dose			138.0	130.0
Xanomeline High Dose			120.0	132.0
Xanomeline High Dose			122.0	130.0
Xanomeline High Dose			115.0	130.0
Xanomeline Low Dose		Week 2	147.0	135.0	12.0
Xanomeline Low Dose		Week 2	139.0	124.0	15.0
Xanomeline Low Dose		Week 2	139.0	130.0	9.0
Xanomeline Low Dose		Week 4	145.0	135.0	10.0
Xanomeline Low Dose		Week 4	143.0	124.0	19.0
Xanomeline Low Dose		Week 4	146.0	130.0	16.0
Xanomeline Low Dose			140.0	135.0
Xanomeline Low Dose			123.0	124.0
Xanomeline Low Dose			139.0	130.0
Xanomeline Low Dose			148.0	135.0
Xanomeline Low Dose			147.0	124.0
Xanomeline Low Dose			146.0	130.0
Xanomeline Low Dose		Week 12	136.0	162.0	-26.0
Xanomeline Low Dose		Week 12	144.0	154.0	-10.0
Xanomeline Low Dose		Week 12	152.0	156.0	-4.0
Xanomeline Low Dose		Week 16	156.0	162.0	-6.0
Xanomeline Low Dose		Week 16	138.0	154.0	-16.0
Xanomeline Low Dose		Week 16	155.0	156.0	-1.0
Xanomeline Low Dose		Week 2	178.0	162.0	16.0
Xanomeline Low Dose		Week 2	174.0	154.0	20.0
Xanomeline Low Dose		Week 2	153.0	156.0	-3.0
Xanomeline Low Dose		Week 20	150.0	162.0	-12.0
Xanomeline Low Dose		Week 20	160.0	154.0	6.0
Xanomeline Low Dose		Week 20	154.0	156.0	-2.0
Xanomeline Low Dose		Week 24	173.0	162.0	11.0
Xanomeline Low Dose		Week 24	164.0	154.0	10.0
Xanomeline Low Dose		Week 24	168.0	156.0	12.0
Xanomeline Low Dose		Week 26	173.0	162.0	11.0
Xanomeline Low Dose		Week 26	166.0	154.0	12.0
Xanomeline Low Dose		Week 26	171.0	156.0	15.0
Xanomeline Low Dose		Week 4	152.0	162.0	-10.0
Xanomeline Low Dose		Week 4	144.0	154.0	-10.0
Xanomeline Low Dose		Week 4	160.0	156.0	4.0
Xanomeline Low Dose		Week 6	142.0	162.0	-20.0
Xanomeline Low Dose		Week 6	164.0	154.0	10.0
Xanomeline Low Dose		Week 6	150.0	156.0	-6.0
Xanomeline Low Dose		Week 8	137.0	162.0	-25.0
Xanomeline Low Dose		Week 8	130.0	154.0	-24.0
Xanomeline Low Dose		Week 8	144.0	156.0	-12.0
Xanomeline Low Dose			158.0	162.0
Xanomeline Low Dose			152.0	154.0
Xanomeline Low Dose			148.0	156.0
Xanomeline Low Dose			154.0	162.0
Xanomeline Low Dose			160.0	154.0
Xanomeline Low Dose			160.0	156.0
Placebo		Week 12	115.0	129.0	-14.0
Placebo		Week 12	95.0	145.0	-50.0
Placebo		Week 12	110.0	138.0	-28.0
Placebo		Week 16	131.0	129.0	2.0
Placebo		Week 16	138.0	145.0	-7.0
Placebo		Week 16	132.0	138.0	-6.0
Placebo		Week 2	130.0	129.0	1.0
Placebo		Week 2	131.0	145.0	-14.0
Placebo		Week 2	144.0	138.0	6.0
Placebo		Week 20	130.0	129.0	1.0
Placebo		Week 20	131.0	145.0	-14.0
Placebo		Week 20	147.0	138.0	9.0
Placebo		Week 24	125.0	129.0	-4.0
Placebo		Week 24	114.0	145.0	-31.0
Placebo		Week 24	144.0	138.0	6.0
Placebo		Week 26	137.0	129.0	8.0
Placebo		Week 26	114.0	145.0	-31.0
Placebo		Week 26	137.0	138.0	-1.0
Placebo		Week 4	128.0	129.0	-1.0
Placebo		Week 4	138.0	145.0	-7.0
Placebo		Week 4	130.0	138.0	-8.0
Placebo		Week 6	139.0	129.0	10.0
Placebo		Week 6	148.0	145.0	3.0
Placebo		Week 6	138.0	138.0	0.0
Placebo		Week 8	139.0	129.0	10.0
Placebo		Week 8	138.0	145.0	-7.0
Placebo		Week 8	145.0	138.0	7.0
Placebo			130.0	129.0
Placebo			122.0	145.0
Placebo			130.0	138.0
Xanomeline Low Dose		Week 2	113.0	135.0	-22.0
Xanomeline Low Dose		Week 2	98.0	116.0	-18.0
Xanomeline Low Dose		Week 2	96.0	108.0	-12.0
Xanomeline Low Dose		Week 4	115.0	135.0	-20.0
Xanomeline Low Dose		Week 4	106.0	116.0	-10.0
Xanomeline Low Dose		Week 4	106.0	108.0	-2.0
Xanomeline Low Dose		Week 6	123.0	135.0	-12.0
Xanomeline Low Dose		Week 6	123.0	116.0	7.0
Xanomeline Low Dose		Week 6	123.0	108.0	15.0
Xanomeline Low Dose		Week 8	156.0	135.0	21.0
Xanomeline Low Dose		Week 8	114.0	116.0	-2.0
Xanomeline Low Dose		Week 8	127.0	108.0	19.0
Xanomeline Low Dose			144.0	135.0
Xanomeline Low Dose			115.0	116.0
Xanomeline Low Dose			130.0	108.0
Xanomeline Low Dose			130.0	135.0
Xanomeline Low Dose			91.0	116.0
Xanomeline Low Dose			110.0	108.0
Placebo		Week 12	131.0	138.0	-7.0
Placebo		Week 12	147.0	124.0	23.0
Placebo		Week 12	138.0	132.0	6.0
Placebo		Week 16	134.0	138.0	-4.0
Placebo		Week 16	124.0	124.0	0.0
Placebo		Week 16	143.0	132.0	11.0
Placebo		Week 2	158.0	138.0	20.0
Placebo		Week 2	159.0	124.0	35.0
Placebo		Week 2	144.0	132.0	12.0
Placebo		Week 20	136.0	138.0	-2.0
Placebo		Week 20	120.0	124.0	-4.0
Placebo		Week 20	129.0	132.0	-3.0
Placebo		Week 24	123.0	138.0	-15.0
Placebo		Week 24	126.0	124.0	2.0
Placebo		Week 24	131.0	132.0	-1.0
Placebo		Week 26	160.0	138.0	22.0
Placebo		Week 26	146.0	124.0	22.0
Placebo		Week 26	146.0	132.0	14.0
Placebo		Week 4	135.0	138.0	-3.0
Placebo		Week 4	145.0	124.0	21.0
Placebo		Week 4	147.0	132.0	15.0
Placebo		Week 6	131.0	138.0	-7.0
Placebo		Week 6	131.0	124.0	7.0
Placebo		Week 6	131.0	132.0	-1.0
Placebo		Week 8	142.0	138.0	4.0
Placebo		Week 8	130.0	124.0	6.0
Placebo		Week 8	137.0	132.0	5.0
Placebo			150.0	138.0
Placebo			134.0	124.0
Placebo			146.0	132.0
Placebo			144.0	138.0
Placebo			138.0	124.0
Placebo			142.0	132.0
Xanomeline High Dose		Week 12	146.0	153.0	-7.0
Xanomeline High Dose		Week 12	130.0	148.0	-18.0
Xanomeline High Dose		Week 12	138.0	154.0	-16.0
Xanomeline High Dose		Week 16	139.0	153.0	-14.0
Xanomeline High Dose		Week 16	123.0	148.0	-25.0
Xanomeline High Dose		Week 16	131.0	154.0	-23.0
Xanomeline High Dose		Week 2	140.0	153.0	-13.0
Xanomeline High Dose		Week 2	139.0	148.0	-9.0
Xanomeline High Dose		Week 2	147.0	154.0	-7.0
Xanomeline High Dose		Week 20	145.0	153.0	-8.0
Xanomeline High Dose		Week 20	132.0	148.0	-16.0
Xanomeline High Dose		Week 20	139.0	154.0	-15.0
Xanomeline High Dose		Week 24	139.0	153.0	-14.0
Xanomeline High Dose		Week 24	125.0	148.0	-23.0
Xanomeline High Dose		Week 24	143.0	154.0	-11.0
Xanomeline High Dose		Week 4	136.0	153.0	-17.0
Xanomeline High Dose		Week 4	139.0	148.0	-9.0
Xanomeline High Dose		Week 4	137.0	154.0	-17.0
Xanomeline High Dose		Week 6	138.0	153.0	-15.0
Xanomeline High Dose		Week 6	120.0	148.0	-28.0
Xanomeline High Dose		Week 6	130.0	154.0	-24.0
Xanomeline High Dose		Week 8	140.0	153.0	-13.0
Xanomeline High Dose		Week 8	124.0	148.0	-24.0
Xanomeline High Dose		Week 8	131.0	154.0	-23.0
Xanomeline High Dose			147.0	153.0
Xanomeline High Dose			146.0	148.0
Xanomeline High Dose			148.0	154.0
Xanomeline High Dose			159.0	153.0
Xanomeline High Dose			149.0	148.0
Xanomeline High Dose			131.0	154.0
Xanomeline High Dose		Week 12	123.0	122.0	1.0
Xanomeline High Dose		Week 12	131.0	132.0	-1.0
Xanomeline High Dose		Week 12	131.0	124.0	7.0
Xanomeline High Dose		Week 2	121.0	122.0	-1.0
Xanomeline High Dose		Week 2	130.0	132.0	-2.0
Xanomeline High Dose		Week 2	123.0	124.0	-1.0
Xanomeline High Dose		Week 4	122.0	122.0	0.0
Xanomeline High Dose		Week 4	115.0	132.0	-17.0
Xanomeline High Dose		Week 4	124.0	124.0	0.0
Xanomeline High Dose		Week 6	122.0	122.0	0.0
Xanomeline High Dose		Week 6	115.0	132.0	-17.0
Xanomeline High Dose		Week 6	122.0	124.0	-2.0
Xanomeline High Dose		Week 8	130.0	122.0	8.0
Xanomeline High Dose		Week 8	123.0	132.0	-9.0
Xanomeline High Dose		Week 8	124.0	124.0	0.0
Xanomeline High Dose			123.0	122.0
Xanomeline High Dose			118.0	132.0
Xanomeline High Dose			131.0	124.0
Xanomeline High Dose			128.0	122.0
Xanomeline High Dose			120.0	132.0
Xanomeline High Dose			130.0	124.0
Xanomeline High Dose		Week 12	107.0	106.0	1.0
Xanomeline High Dose		Week 12	107.0	107.0	0.0
Xanomeline High Dose		Week 12	100.0	108.0	-8.0
Xanomeline High Dose		Week 16	121.0	106.0	15.0
Xanomeline High Dose		Week 16	114.0	107.0	7.0
Xanomeline High Dose		Week 16	107.0	108.0	-1.0
Xanomeline High Dose		Week 2	120.0	106.0	14.0
Xanomeline High Dose		Week 2	116.0	107.0	9.0
Xanomeline High Dose		Week 2	124.0	108.0	16.0
Xanomeline High Dose		Week 20	107.0	106.0	1.0
Xanomeline High Dose		Week 20	106.0	107.0	-1.0
Xanomeline High Dose		Week 20	108.0	108.0	0.0
Xanomeline High Dose		Week 24	114.0	106.0	8.0
Xanomeline High Dose		Week 24	123.0	107.0	16.0
Xanomeline High Dose		Week 24	123.0	108.0	15.0
Xanomeline High Dose		Week 26	113.0	106.0	7.0
Xanomeline High Dose		Week 26	121.0	107.0	14.0
Xanomeline High Dose		Week 26	113.0	108.0	5.0
Xanomeline High Dose		Week 4	108.0	106.0	2.0
Xanomeline High Dose		Week 4	113.0	107.0	6.0
Xanomeline High Dose		Week 4	105.0	108.0	-3.0
Xanomeline High Dose		Week 6	122.0	106.0	16.0
Xanomeline High Dose		Week 6	129.0	107.0	22.0
Xanomeline High Dose		Week 6	122.0	108.0	14.0
Xanomeline High Dose		Week 8	106.0	106.0	0.0
Xanomeline High Dose		Week 8	91.0	107.0	-16.0
Xanomeline High Dose		Week 8	100.0	108.0	-8.0
Xanomeline High Dose			112.0	106.0
Xanomeline High Dose			113.0	107.0
Xanomeline High Dose			114.0	108.0
Xanomeline Low Dose		Week 12	123.0	137.0	-14.0
Xanomeline Low Dose		Week 12	116.0	117.0	-1.0
Xanomeline Low Dose		Week 12	116.0	125.0	-9.0
Xanomeline Low Dose		Week 2	130.0	137.0	-7.0
Xanomeline Low Dose		Week 2	115.0	117.0	-2.0
Xanomeline Low Dose		Week 2	115.0	125.0	-10.0
Xanomeline Low Dose		Week 4	130.0	137.0	-7.0
Xanomeline Low Dose		Week 4	121.0	117.0	4.0
Xanomeline Low Dose		Week 4	115.0	125.0	-10.0
Xanomeline Low Dose		Week 6	138.0	137.0	1.0
Xanomeline Low Dose		Week 6	130.0	117.0	13.0
Xanomeline Low Dose		Week 6	139.0	125.0	14.0
Xanomeline Low Dose		Week 8	129.0	137.0	-8.0
Xanomeline Low Dose		Week 8	124.0	117.0	7.0
Xanomeline Low Dose		Week 8	123.0	125.0	-2.0
Xanomeline Low Dose			123.0	137.0
Xanomeline Low Dose			122.0	117.0
Xanomeline Low Dose			122.0	125.0
Xanomeline Low Dose			131.0	137.0
Xanomeline Low Dose			107.0	117.0
Xanomeline Low Dose			116.0	125.0
Xanomeline High Dose		Week 12	115.0	131.0	-16.0
Xanomeline High Dose		Week 12	124.0	137.0	-13.0
Xanomeline High Dose		Week 12	131.0	136.0	-5.0
Xanomeline High Dose		Week 2	114.0	131.0	-17.0
Xanomeline High Dose		Week 2	114.0	137.0	-23.0
Xanomeline High Dose		Week 2	123.0	136.0	-13.0
Xanomeline High Dose		Week 4	123.0	131.0	-8.0
Xanomeline High Dose		Week 4	115.0	137.0	-22.0
Xanomeline High Dose		Week 4	131.0	136.0	-5.0
Xanomeline High Dose		Week 6	108.0	131.0	-23.0
Xanomeline High Dose		Week 6	115.0	137.0	-22.0
Xanomeline High Dose		Week 6	123.0	136.0	-13.0
Xanomeline High Dose		Week 8	115.0	131.0	-16.0
Xanomeline High Dose		Week 8	115.0	137.0	-22.0
Xanomeline High Dose		Week 8	114.0	136.0	-22.0
Xanomeline High Dose			115.0	131.0
Xanomeline High Dose			115.0	137.0
Xanomeline High Dose			115.0	136.0
Xanomeline High Dose			131.0	131.0
Xanomeline High Dose			133.0	137.0
Xanomeline High Dose			130.0	136.0
Xanomeline Low Dose		Week 12	115.0	122.0	-7.0
Xanomeline Low Dose		Week 12	108.0	107.0	1.0
Xanomeline Low Dose		Week 12	107.0	115.0	-8.0
Xanomeline Low Dose		Week 16	123.0	122.0	1.0
Xanomeline Low Dose		Week 16	115.0	107.0	8.0
Xanomeline Low Dose		Week 16	123.0	115.0	8.0
Xanomeline Low Dose		Week 2	139.0	122.0	17.0
Xanomeline Low Dose		Week 2	116.0	107.0	9.0
Xanomeline Low Dose		Week 2	125.0	115.0	10.0
Xanomeline Low Dose		Week 20	116.0	122.0	-6.0
Xanomeline Low Dose		Week 20	100.0	107.0	-7.0
Xanomeline Low Dose		Week 20	100.0	115.0	-15.0
Xanomeline Low Dose		Week 24	122.0	122.0	0.0
Xanomeline Low Dose		Week 24	115.0	107.0	8.0
Xanomeline Low Dose		Week 24	116.0	115.0	1.0
Xanomeline Low Dose		Week 26	115.0	122.0	-7.0
Xanomeline Low Dose		Week 26	99.0	107.0	-8.0
Xanomeline Low Dose		Week 26	100.0	115.0	-15.0
Xanomeline Low Dose		Week 4	116.0	122.0	-6.0
Xanomeline Low Dose		Week 4	115.0	107.0	8.0
Xanomeline Low Dose		Week 4	115.0	115.0	0.0
Xanomeline Low Dose		Week 6	122.0	122.0	0.0
Xanomeline Low Dose		Week 6	115.0	107.0	8.0
Xanomeline Low Dose		Week 6	113.0	115.0	-2.0
Xanomeline Low Dose		Week 8	114.0	122.0	-8.0
Xanomeline Low Dose		Week 8	115.0	107.0	8.0
Xanomeline Low Dose		Week 8	113.0	115.0	-2.0
Xanomeline Low Dose			137.0	122.0
Xanomeline Low Dose			122.0	107.0
Xanomeline Low Dose			116.0	115.0
Xanomeline Low Dose			123.0	122.0
Xanomeline Low Dose			124.0	107.0
Xanomeline Low Dose			107.0	115.0
Xanomeline Low Dose		Week 12	119.0	122.0	-3.0
Xanomeline Low Dose		Week 12	105.0	112.0	-7.0
Xanomeline Low Dose		Week 12	110.0	108.0	2.0
Xanomeline Low Dose		Week 16	120.0	122.0	-2.0
Xanomeline Low Dose		Week 16	104.0	112.0	-8.0
Xanomeline Low Dose		Week 16	110.0	108.0	2.0
Xanomeline Low Dose		Week 2	113.0	122.0	-9.0
Xanomeline Low Dose		Week 2	106.0	112.0	-6.0
Xanomeline Low Dose		Week 2	107.0	108.0	-1.0
Xanomeline Low Dose		Week 20	106.0	122.0	-16.0
Xanomeline Low Dose		Week 20	106.0	112.0	-6.0
Xanomeline Low Dose		Week 20	107.0	108.0	-1.0
Xanomeline Low Dose		Week 24	107.0	122.0	-15.0
Xanomeline Low Dose		Week 24	101.0	112.0	-11.0
Xanomeline Low Dose		Week 24	101.0	108.0	-7.0
Xanomeline Low Dose		Week 26	109.0	122.0	-13.0
Xanomeline Low Dose		Week 26	102.0	112.0	-10.0
Xanomeline Low Dose		Week 26	108.0	108.0	0.0
Xanomeline Low Dose		Week 4	122.0	122.0	0.0
Xanomeline Low Dose		Week 4	112.0	112.0	0.0
Xanomeline Low Dose		Week 4	110.0	108.0	2.0
Xanomeline Low Dose		Week 6	118.0	122.0	-4.0
Xanomeline Low Dose		Week 6	106.0	112.0	-6.0
Xanomeline Low Dose		Week 6	104.0	108.0	-4.0
Xanomeline Low Dose		Week 8	107.0	122.0	-15.0
Xanomeline Low Dose		Week 8	107.0	112.0	-5.0
Xanomeline Low Dose		Week 8	107.0	108.0	-1.0
Xanomeline Low Dose			129.0	122.0
Xanomeline Low Dose			114.0	112.0
Xanomeline Low Dose			115.0	108.0
Xanomeline Low Dose			116.0	122.0
Xanomeline Low Dose			108.0	112.0
Xanomeline Low Dose			108.0	108.0
Xanomeline Low Dose		Week 2	140.0	139.0	1.0
Xanomeline Low Dose		Week 2	145.0	146.0	-1.0
Xanomeline Low Dose		Week 2	147.0	146.0	1.0
Xanomeline Low Dose			138.0	139.0
Xanomeline Low Dose			147.0	146.0
Xanomeline Low Dose			145.0	146.0
Placebo		Week 12	121.0	126.0	-5.0
Placebo		Week 12	113.0	108.0	5.0
Placebo		Week 12	121.0	116.0	5.0
Placebo		Week 16	120.0	126.0	-6.0
Placebo		Week 16	114.0	108.0	6.0
Placebo		Week 16	123.0	116.0	7.0
Placebo		Week 2	116.0	126.0	-10.0
Placebo		Week 2	110.0	108.0	2.0
Placebo		Week 2	118.0	116.0	2.0
Placebo		Week 20	113.0	126.0	-13.0
Placebo		Week 20	104.0	108.0	-4.0
Placebo		Week 20	122.0	116.0	6.0
Placebo		Week 24	122.0	126.0	-4.0
Placebo		Week 24	120.0	108.0	12.0
Placebo		Week 24	113.0	116.0	-3.0
Placebo		Week 4	113.0	126.0	-13.0
Placebo		Week 4	106.0	108.0	-2.0
Placebo		Week 4	123.0	116.0	7.0
Placebo		Week 6	129.0	126.0	3.0
Placebo		Week 6	122.0	108.0	14.0
Placebo		Week 6	115.0	116.0	-1.0
Placebo		Week 8	115.0	126.0	-11.0
Placebo		Week 8	105.0	108.0	-3.0
Placebo		Week 8	108.0	116.0	-8.0
Placebo			114.0	126.0
Placebo			107.0	108.0
Placebo			114.0	116.0
Placebo			114.0	126.0
Placebo			106.0	108.0
Placebo			118.0	116.0
Placebo		Week 12	123.0	126.0	-3.0
Placebo		Week 12	124.0	122.0	2.0
Placebo		Week 12	131.0	107.0	24.0
Placebo		Week 16	146.0	126.0	20.0
Placebo		Week 16	139.0	122.0	17.0
Placebo		Week 16	152.0	107.0	45.0
Placebo		Week 2	121.0	126.0	-5.0
Placebo		Week 2	119.0	122.0	-3.0
Placebo		Week 2	107.0	107.0	0.0
Placebo		Week 20	114.0	126.0	-12.0
Placebo		Week 20	122.0	122.0	0.0
Placebo		Week 20	100.0	107.0	-7.0
Placebo		Week 24	130.0	126.0	4.0
Placebo		Week 24	134.0	122.0	12.0
Placebo		Week 24	122.0	107.0	15.0
Placebo		Week 26	100.0	126.0	-26.0
Placebo		Week 26	107.0	122.0	-15.0
Placebo		Week 26	115.0	107.0	8.0
Placebo		Week 4	108.0	126.0	-18.0
Placebo		Week 4	100.0	122.0	-22.0
Placebo		Week 4	111.0	107.0	4.0
Placebo		Week 6	115.0	126.0	-11.0
Placebo		Week 6	114.0	122.0	-8.0
Placebo		Week 6	109.0	107.0	2.0
Placebo		Week 8	129.0	126.0	3.0
Placebo		Week 8	127.0	122.0	5.0
Placebo		Week 8	131.0	107.0	24.0
Placebo			108.0	126.0
Placebo			132.0	122.0
Placebo			123.0	107.0
Placebo			116.0	126.0
Placebo			100.0	122.0
Placebo			97.0	107.0
Xanomeline High Dose		Week 12	114.0	137.0	-23.0
Xanomeline High Dose		Week 12	122.0	138.0	-16.0
Xanomeline High Dose		Week 12	122.0	131.0	-9.0
Xanomeline High Dose		Week 16	138.0	137.0	1.0
Xanomeline High Dose		Week 16	130.0	138.0	-8.0
Xanomeline High Dose		Week 16	140.0	131.0	9.0
Xanomeline High Dose		Week 2	138.0	137.0	1.0
Xanomeline High Dose		Week 2	130.0	138.0	-8.0
Xanomeline High Dose		Week 2	138.0	131.0	7.0
Xanomeline High Dose		Week 20	131.0	137.0	-6.0
Xanomeline High Dose		Week 20	139.0	138.0	1.0
Xanomeline High Dose		Week 20	132.0	131.0	1.0
Xanomeline High Dose		Week 24	142.0	137.0	5.0
Xanomeline High Dose		Week 24	128.0	138.0	-10.0
Xanomeline High Dose		Week 24	132.0	131.0	1.0
Xanomeline High Dose		Week 26	130.0	137.0	-7.0
Xanomeline High Dose		Week 26	115.0	138.0	-23.0
Xanomeline High Dose		Week 26	123.0	131.0	-8.0
Xanomeline High Dose		Week 4	132.0	137.0	-5.0
Xanomeline High Dose		Week 4	117.0	138.0	-21.0
Xanomeline High Dose		Week 4	138.0	131.0	7.0
Xanomeline High Dose		Week 6	129.0	137.0	-8.0
Xanomeline High Dose		Week 6	129.0	138.0	-9.0
Xanomeline High Dose		Week 6	129.0	131.0	-2.0
Xanomeline High Dose		Week 8	144.0	137.0	7.0
Xanomeline High Dose		Week 8	137.0	138.0	-1.0
Xanomeline High Dose		Week 8	138.0	131.0	7.0
Xanomeline High Dose			136.0	137.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			132.0	131.0
Xanomeline High Dose			145.0	137.0
Xanomeline High Dose			144.0	138.0
Xanomeline High Dose			130.0	131.0
Placebo		Week 2	135.0	159.0	-24.0
Placebo		Week 2	130.0	136.0	-6.0
Placebo		Week 2	129.0	134.0	-5.0
Placebo		Week 12	138.0	138.0	0.0
Placebo		Week 12	137.0	144.0	-7.0
Placebo		Week 12	131.0	153.0	-22.0
Placebo		Week 16	139.0	138.0	1.0
Placebo		Week 16	138.0	144.0	-6.0
Placebo		Week 16	154.0	153.0	1.0
Placebo		Week 2	131.0	138.0	-7.0
Placebo		Week 2	128.0	144.0	-16.0
Placebo		Week 2	130.0	153.0	-23.0
Placebo		Week 20	139.0	138.0	1.0
Placebo		Week 20	138.0	144.0	-6.0
Placebo		Week 20	138.0	153.0	-15.0
Placebo		Week 24	144.0	138.0	6.0
Placebo		Week 24	145.0	144.0	1.0
Placebo		Week 24	145.0	153.0	-8.0
Placebo		Week 26	145.0	138.0	7.0
Placebo		Week 26	145.0	144.0	1.0
Placebo		Week 26	139.0	153.0	-14.0
Placebo		Week 4	154.0	138.0	16.0
Placebo		Week 4	146.0	144.0	2.0
Placebo		Week 4	150.0	153.0	-3.0
Placebo		Week 6	145.0	138.0	7.0
Placebo		Week 6	138.0	144.0	-6.0
Placebo		Week 6	146.0	153.0	-7.0
Placebo		Week 8	145.0	138.0	7.0
Placebo		Week 8	130.0	144.0	-14.0
Placebo		Week 8	138.0	153.0	-15.0
Placebo			129.0	138.0
Placebo			136.0	144.0
Placebo			137.0	153.0
Placebo			138.0	138.0
Placebo			144.0	144.0
Placebo			138.0	153.0
Placebo		Week 12	131.0	138.0	-7.0
Placebo		Week 12	130.0	130.0	0.0
Placebo		Week 12	138.0	140.0	-2.0
Placebo		Week 16	138.0	138.0	0.0
Placebo		Week 16	137.0	130.0	7.0
Placebo		Week 16	122.0	140.0	-18.0
Placebo		Week 2	122.0	138.0	-16.0
Placebo		Week 2	130.0	130.0	0.0
Placebo		Week 2	145.0	140.0	5.0
Placebo		Week 20	129.0	138.0	-9.0
Placebo		Week 20	129.0	130.0	-1.0
Placebo		Week 20	138.0	140.0	-2.0
Placebo		Week 24	113.0	138.0	-25.0
Placebo		Week 24	130.0	130.0	0.0
Placebo		Week 24	133.0	140.0	-7.0
Placebo		Week 26	133.0	138.0	-5.0
Placebo		Week 26	123.0	130.0	-7.0
Placebo		Week 26	116.0	140.0	-24.0
Placebo		Week 4	131.0	138.0	-7.0
Placebo		Week 4	129.0	130.0	-1.0
Placebo		Week 4	147.0	140.0	7.0
Placebo		Week 6	115.0	138.0	-23.0
Placebo		Week 6	116.0	130.0	-14.0
Placebo		Week 6	124.0	140.0	-16.0
Placebo		Week 8	143.0	138.0	5.0
Placebo		Week 8	128.0	130.0	-2.0
Placebo		Week 8	138.0	140.0	-2.0
Placebo			129.0	138.0
Placebo			129.0	130.0
Placebo			129.0	140.0
Placebo			129.0	138.0
Placebo			129.0	130.0
Placebo			131.0	140.0
Xanomeline Low Dose		Week 2	168.0	178.0	-10.0
Xanomeline Low Dose		Week 2	178.0	186.0	-8.0
Xanomeline Low Dose		Week 2	174.0	180.0	-6.0
Xanomeline Low Dose		Week 4	172.0	178.0	-6.0
Xanomeline Low Dose		Week 4	164.0	186.0	-22.0
Xanomeline Low Dose		Week 4	178.0	180.0	-2.0
Xanomeline Low Dose		Week 6	160.0	178.0	-18.0
Xanomeline Low Dose		Week 6	178.0	186.0	-8.0
Xanomeline Low Dose		Week 6	170.0	180.0	-10.0
Placebo		Week 12	129.0	118.0	11.0
Placebo		Week 12	134.0	116.0	18.0
Placebo		Week 12	133.0	116.0	17.0
Placebo		Week 16	144.0	118.0	26.0
Placebo		Week 16	146.0	116.0	30.0
Placebo		Week 16	150.0	116.0	34.0
Placebo		Week 2	136.0	118.0	18.0
Placebo		Week 2	124.0	116.0	8.0
Placebo		Week 2	118.0	116.0	2.0
Placebo		Week 20	116.0	118.0	-2.0
Placebo		Week 20	130.0	116.0	14.0
Placebo		Week 20	131.0	116.0	15.0
Placebo		Week 24	135.0	118.0	17.0
Placebo		Week 24	138.0	116.0	22.0
Placebo		Week 24	144.0	116.0	28.0
Placebo		Week 26	106.0	118.0	-12.0
Placebo		Week 26	120.0	116.0	4.0
Placebo		Week 26	110.0	116.0	-6.0
Placebo		Week 4	108.0	118.0	-10.0
Placebo		Week 4	107.0	116.0	-9.0
Placebo		Week 4	114.0	116.0	-2.0
Placebo		Week 6	108.0	118.0	-10.0
Placebo		Week 6	122.0	116.0	6.0
Placebo		Week 6	115.0	116.0	-1.0
Placebo		Week 8	129.0	118.0	11.0
Placebo		Week 8	131.0	116.0	15.0
Placebo		Week 8	145.0	116.0	29.0
Placebo			116.0	118.0
Placebo			127.0	116.0
Placebo			121.0	116.0
Placebo			116.0	118.0
Placebo			123.0	116.0
Placebo			130.0	116.0
Xanomeline Low Dose		Week 12	131.0	139.0	-8.0
Xanomeline Low Dose		Week 12	139.0	148.0	-9.0
Xanomeline Low Dose		Week 12	131.0	147.0	-16.0
Xanomeline Low Dose		Week 16	131.0	139.0	-8.0
Xanomeline Low Dose		Week 16	146.0	148.0	-2.0
Xanomeline Low Dose		Week 16	147.0	147.0	0.0
Xanomeline Low Dose		Week 2	147.0	139.0	8.0
Xanomeline Low Dose		Week 2	146.0	148.0	-2.0
Xanomeline Low Dose		Week 2	141.0	147.0	-6.0
Xanomeline Low Dose		Week 20	159.0	139.0	20.0
Xanomeline Low Dose		Week 20	149.0	148.0	1.0
Xanomeline Low Dose		Week 20	141.0	147.0	-6.0
Xanomeline Low Dose		Week 24	146.0	139.0	7.0
Xanomeline Low Dose		Week 24	139.0	148.0	-9.0
Xanomeline Low Dose		Week 24	147.0	147.0	0.0
Xanomeline Low Dose		Week 26	139.0	139.0	0.0
Xanomeline Low Dose		Week 26	134.0	148.0	-14.0
Xanomeline Low Dose		Week 26	141.0	147.0	-6.0
Xanomeline Low Dose		Week 4	148.0	139.0	9.0
Xanomeline Low Dose		Week 4	141.0	148.0	-7.0
Xanomeline Low Dose		Week 4	141.0	147.0	-6.0
Xanomeline Low Dose		Week 6	146.0	139.0	7.0
Xanomeline Low Dose		Week 6	156.0	148.0	8.0
Xanomeline Low Dose		Week 6	140.0	147.0	-7.0
Xanomeline Low Dose		Week 8	147.0	139.0	8.0
Xanomeline Low Dose		Week 8	141.0	148.0	-7.0
Xanomeline Low Dose		Week 8	149.0	147.0	2.0
Xanomeline Low Dose			146.0	139.0
Xanomeline Low Dose			137.0	148.0
Xanomeline Low Dose			129.0	147.0
Xanomeline Low Dose			140.0	139.0
Xanomeline Low Dose			138.0	148.0
Xanomeline Low Dose			150.0	147.0
Xanomeline High Dose		Week 2	138.0	159.0	-21.0
Xanomeline High Dose		Week 2	131.0	138.0	-7.0
Xanomeline High Dose		Week 2	139.0	138.0	1.0
Xanomeline High Dose		Week 4	138.0	159.0	-21.0
Xanomeline High Dose		Week 4	121.0	138.0	-17.0
Xanomeline High Dose		Week 4	137.0	138.0	-1.0
Xanomeline High Dose			138.0	159.0
Xanomeline High Dose			109.0	138.0
Xanomeline High Dose			129.0	138.0
Xanomeline High Dose			136.0	159.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			139.0	138.0
Xanomeline Low Dose		Week 2	150.0	144.0	6.0
Xanomeline Low Dose		Week 2	130.0	129.0	1.0
Xanomeline Low Dose		Week 2	140.0	140.0	0.0
Xanomeline Low Dose		Week 4	160.0	144.0	16.0
Xanomeline Low Dose		Week 4	150.0	129.0	21.0
Xanomeline Low Dose		Week 4	157.0	140.0	17.0
Xanomeline Low Dose		Week 6	130.0	144.0	-14.0
Xanomeline Low Dose		Week 6	116.0	129.0	-13.0
Xanomeline Low Dose		Week 6	112.0	140.0	-28.0
Xanomeline Low Dose		Week 8	132.0	144.0	-12.0
Xanomeline Low Dose		Week 8	130.0	129.0	1.0
Xanomeline Low Dose		Week 8	115.0	140.0	-25.0
Xanomeline Low Dose			136.0	144.0
Xanomeline Low Dose			130.0	129.0
Xanomeline Low Dose			116.0	140.0
Xanomeline Low Dose			96.0	144.0
Xanomeline Low Dose			90.0	129.0
Xanomeline Low Dose			86.0	140.0
Placebo		Week 12	130.0	130.0	0.0
Placebo		Week 12	128.0	108.0	20.0
Placebo		Week 12	126.0	110.0	16.0
Placebo		Week 16	120.0	130.0	-10.0
Placebo		Week 16	122.0	108.0	14.0
Placebo		Week 16	118.0	110.0	8.0
Placebo		Week 2	118.0	130.0	-12.0
Placebo		Week 2	112.0	108.0	4.0
Placebo		Week 2	122.0	110.0	12.0
Placebo		Week 20	122.0	130.0	-8.0
Placebo		Week 20	118.0	108.0	10.0
Placebo		Week 20	118.0	110.0	8.0
Placebo		Week 24	122.0	130.0	-8.0
Placebo		Week 24	118.0	108.0	10.0
Placebo		Week 24	122.0	110.0	12.0
Placebo		Week 26	122.0	130.0	-8.0
Placebo		Week 26	124.0	108.0	16.0
Placebo		Week 26	120.0	110.0	10.0
Placebo		Week 4	120.0	130.0	-10.0
Placebo		Week 4	130.0	108.0	22.0
Placebo		Week 4	132.0	110.0	22.0
Placebo		Week 6	128.0	130.0	-2.0
Placebo		Week 6	118.0	108.0	10.0
Placebo		Week 6	128.0	110.0	18.0
Placebo		Week 8	108.0	130.0	-22.0
Placebo		Week 8	110.0	108.0	2.0
Placebo		Week 8	114.0	110.0	4.0
Placebo			122.0	130.0
Placebo			114.0	108.0
Placebo			110.0	110.0
Placebo			118.0	130.0
Placebo			120.0	108.0
Placebo			122.0	110.0
Xanomeline High Dose		Week 12	122.0	144.0	-22.0
Xanomeline High Dose		Week 12	114.0	140.0	-26.0
Xanomeline High Dose		Week 12	118.0	150.0	-32.0
Xanomeline High Dose		Week 2	154.0	144.0	10.0
Xanomeline High Dose		Week 2	137.0	140.0	-3.0
Xanomeline High Dose		Week 2	135.0	150.0	-15.0
Xanomeline High Dose		Week 4	138.0	144.0	-6.0
Xanomeline High Dose		Week 4	127.0	140.0	-13.0
Xanomeline High Dose		Week 4	120.0	150.0	-30.0
Xanomeline High Dose		Week 6	144.0	144.0	0.0
Xanomeline High Dose		Week 6	144.0	140.0	4.0
Xanomeline High Dose		Week 6	128.0	150.0	-22.0
Xanomeline High Dose		Week 8	152.0	144.0	8.0
Xanomeline High Dose		Week 8	140.0	140.0	0.0
Xanomeline High Dose		Week 8	148.0	150.0	-2.0
Xanomeline High Dose			154.0	144.0
Xanomeline High Dose			137.0	140.0
Xanomeline High Dose			135.0	150.0
Xanomeline High Dose			150.0	144.0
Xanomeline High Dose			130.0	140.0
Xanomeline High Dose			130.0	150.0
Xanomeline Low Dose		Week 12	118.0	130.0	-12.0
Xanomeline Low Dose		Week 12	124.0	120.0	4.0
Xanomeline Low Dose		Week 12	126.0	130.0	-4.0
Xanomeline Low Dose		Week 2	120.0	130.0	-10.0
Xanomeline Low Dose		Week 2	122.0	120.0	2.0
Xanomeline Low Dose		Week 2	130.0	130.0	0.0
Xanomeline Low Dose		Week 4	118.0	130.0	-12.0
Xanomeline Low Dose		Week 4	110.0	120.0	-10.0
Xanomeline Low Dose		Week 4	112.0	130.0	-18.0
Xanomeline Low Dose		Week 6	110.0	130.0	-20.0
Xanomeline Low Dose		Week 6	106.0	120.0	-14.0
Xanomeline Low Dose		Week 6	108.0	130.0	-22.0
Xanomeline Low Dose		Week 8	120.0	130.0	-10.0
Xanomeline Low Dose		Week 8	124.0	120.0	4.0
Xanomeline Low Dose		Week 8	124.0	130.0	-6.0
Xanomeline Low Dose			116.0	130.0
Xanomeline Low Dose			120.0	120.0
Xanomeline Low Dose			118.0	130.0
Xanomeline Low Dose			110.0	130.0
Xanomeline Low Dose			110.0	120.0
Xanomeline Low Dose			112.0	130.0
Placebo		Week 2	140.0	142.0	-2.0
Placebo		Week 2	150.0	150.0	0.0
Placebo		Week 2	142.0	144.0	-2.0
Placebo		Week 4	150.0	142.0	8.0
Placebo		Week 4	140.0	150.0	-10.0
Placebo		Week 4	144.0	144.0	0.0
Placebo			150.0	142.0
Placebo			148.0	150.0
Placebo			148.0	144.0
Placebo			140.0	142.0
Placebo			148.0	150.0
Placebo			146.0	144.0
Placebo		Week 12	130.0	142.0	-12.0
Placebo		Week 12	130.0	150.0	-20.0
Placebo		Week 12	130.0	156.0	-26.0
Placebo		Week 16	110.0	142.0	-32.0
Placebo		Week 16	118.0	150.0	-32.0
Placebo		Week 16	116.0	156.0	-40.0
Placebo		Week 2	120.0	142.0	-22.0
Placebo		Week 2	130.0	150.0	-20.0
Placebo		Week 2	132.0	156.0	-24.0
Placebo		Week 20	118.0	142.0	-24.0
Placebo		Week 20	114.0	150.0	-36.0
Placebo		Week 20	118.0	156.0	-38.0
Placebo		Week 24	118.0	142.0	-24.0
Placebo		Week 24	120.0	150.0	-30.0
Placebo		Week 24	120.0	156.0	-36.0
Placebo		Week 26	114.0	142.0	-28.0
Placebo		Week 26	116.0	150.0	-34.0
Placebo		Week 26	114.0	156.0	-42.0
Placebo		Week 4	116.0	142.0	-26.0
Placebo		Week 4	118.0	150.0	-32.0
Placebo		Week 4	120.0	156.0	-36.0
Placebo		Week 6	110.0	142.0	-32.0
Placebo		Week 6	112.0	150.0	-38.0
Placebo		Week 6	110.0	156.0	-46.0
Placebo		Week 8	130.0	142.0	-12.0
Placebo		Week 8	128.0	150.0	-22.0
Placebo		Week 8	128.0	156.0	-28.0
Placebo			124.0	142.0
Placebo			120.0	150.0
Placebo			124.0	156.0
Placebo			112.0	142.0
Placebo			116.0	150.0
Placebo			114.0	156.0
Xanomeline Low Dose		Week 12	142.0	152.0	-10.0
Xanomeline Low Dose		Week 12	138.0	144.0	-6.0
Xanomeline Low Dose		Week 12	138.0	128.0	10.0
Xanomeline Low Dose		Week 16	140.0	152.0	-12.0
Xanomeline Low Dose		Week 16	130.0	144.0	-14.0
Xanomeline Low Dose		Week 16	120.0	128.0	-8.0
Xanomeline Low Dose		Week 2	140.0	152.0	-12.0
Xanomeline Low Dose		Week 2	130.0	144.0	-14.0
Xanomeline Low Dose		Week 2	128.0	128.0	0.0
Xanomeline Low Dose		Week 4	120.0	152.0	-32.0
Xanomeline Low Dose		Week 4	130.0	144.0	-14.0
Xanomeline Low Dose		Week 4	126.0	128.0	-2.0
Xanomeline Low Dose		Week 6	150.0	152.0	-2.0
Xanomeline Low Dose		Week 6	140.0	144.0	-4.0
Xanomeline Low Dose		Week 6	130.0	128.0	2.0
Xanomeline Low Dose		Week 8	156.0	152.0	4.0
Xanomeline Low Dose		Week 8	148.0	144.0	4.0
Xanomeline Low Dose		Week 8	146.0	128.0	18.0
Xanomeline Low Dose			134.0	152.0
Xanomeline Low Dose			132.0	144.0
Xanomeline Low Dose			130.0	128.0
Xanomeline Low Dose			120.0	152.0
Xanomeline Low Dose			124.0	144.0
Xanomeline Low Dose			126.0	128.0
Xanomeline Low Dose		Week 2	130.0	140.0	-10.0
Xanomeline Low Dose		Week 2	132.0	150.0	-18.0
Xanomeline Low Dose		Week 2	128.0	124.0	4.0
Xanomeline Low Dose		Week 4	138.0	140.0	-2.0
Xanomeline Low Dose		Week 4	134.0	150.0	-16.0
Xanomeline Low Dose		Week 4	130.0	124.0	6.0
Xanomeline Low Dose		Week 6	122.0	140.0	-18.0
Xanomeline Low Dose		Week 6	110.0	150.0	-40.0
Xanomeline Low Dose		Week 6	112.0	124.0	-12.0
Xanomeline Low Dose			130.0	140.0
Xanomeline Low Dose			130.0	150.0
Xanomeline Low Dose			126.0	124.0
Placebo		Week 12	118.0	120.0	-2.0
Placebo		Week 12	110.0	134.0	-24.0
Placebo		Week 12	110.0	140.0	-30.0
Placebo		Week 16	112.0	120.0	-8.0
Placebo		Week 16	120.0	134.0	-14.0
Placebo		Week 16	118.0	140.0	-22.0
Placebo		Week 2	124.0	120.0	4.0
Placebo		Week 2	122.0	134.0	-12.0
Placebo		Week 2	120.0	140.0	-20.0
Placebo		Week 20	122.0	120.0	2.0
Placebo		Week 20	118.0	134.0	-16.0
Placebo		Week 20	116.0	140.0	-24.0
Placebo		Week 24	118.0	120.0	-2.0
Placebo		Week 24	120.0	134.0	-14.0
Placebo		Week 24	118.0	140.0	-22.0
Placebo		Week 26	114.0	120.0	-6.0
Placebo		Week 26	116.0	134.0	-18.0
Placebo		Week 26	116.0	140.0	-24.0
Placebo		Week 4	130.0	120.0	10.0
Placebo		Week 4	130.0	134.0	-4.0
Placebo		Week 4	128.0	140.0	-12.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	128.0	134.0	-6.0
Placebo		Week 6	126.0	140.0	-14.0
Placebo		Week 8	106.0	120.0	-14.0
Placebo		Week 8	114.0	134.0	-20.0
Placebo		Week 8	112.0	140.0	-28.0
Placebo			122.0	120.0
Placebo			124.0	134.0
Placebo			128.0	140.0
Placebo			132.0	120.0
Placebo			132.0	134.0
Placebo			134.0	140.0
Xanomeline High Dose		Week 12	128.0	150.0	-22.0
Xanomeline High Dose		Week 12	134.0	154.0	-20.0
Xanomeline High Dose		Week 12	140.0	148.0	-8.0
Xanomeline High Dose		Week 16	154.0	150.0	4.0
Xanomeline High Dose		Week 16	140.0	154.0	-14.0
Xanomeline High Dose		Week 16	142.0	148.0	-6.0
Xanomeline High Dose		Week 2	148.0	150.0	-2.0
Xanomeline High Dose		Week 2	150.0	154.0	-4.0
Xanomeline High Dose		Week 2	152.0	148.0	4.0
Xanomeline High Dose		Week 20	124.0	150.0	-26.0
Xanomeline High Dose		Week 20	128.0	154.0	-26.0
Xanomeline High Dose		Week 20	130.0	148.0	-18.0
Xanomeline High Dose		Week 24	118.0	150.0	-32.0
Xanomeline High Dose		Week 24	120.0	154.0	-34.0
Xanomeline High Dose		Week 24	120.0	148.0	-28.0
Xanomeline High Dose		Week 4	130.0	150.0	-20.0
Xanomeline High Dose		Week 4	132.0	154.0	-22.0
Xanomeline High Dose		Week 4	136.0	148.0	-12.0
Xanomeline High Dose		Week 6	130.0	150.0	-20.0
Xanomeline High Dose		Week 6	140.0	154.0	-14.0
Xanomeline High Dose		Week 6	140.0	148.0	-8.0
Xanomeline High Dose		Week 8	122.0	150.0	-28.0
Xanomeline High Dose		Week 8	120.0	154.0	-34.0
Xanomeline High Dose		Week 8	130.0	148.0	-18.0
Xanomeline High Dose			138.0	150.0
Xanomeline High Dose			140.0	154.0
Xanomeline High Dose			142.0	148.0
Xanomeline High Dose			130.0	150.0
Xanomeline High Dose			126.0	154.0
Xanomeline High Dose			128.0	148.0
Xanomeline High Dose		Week 12	140.0	138.0	2.0
Xanomeline High Dose		Week 12	130.0	142.0	-12.0
Xanomeline High Dose		Week 12	132.0	136.0	-4.0
Xanomeline High Dose		Week 16	140.0	138.0	2.0
Xanomeline High Dose		Week 16	142.0	142.0	0.0
Xanomeline High Dose		Week 16	150.0	136.0	14.0
Xanomeline High Dose		Week 2	110.0	138.0	-28.0
Xanomeline High Dose		Week 2	102.0	142.0	-40.0
Xanomeline High Dose		Week 2	100.0	136.0	-36.0
Xanomeline High Dose		Week 4	132.0	138.0	-6.0
Xanomeline High Dose		Week 4	122.0	142.0	-20.0
Xanomeline High Dose		Week 4	148.0	136.0	12.0
Xanomeline High Dose		Week 6	150.0	138.0	12.0
Xanomeline High Dose		Week 6	138.0	142.0	-4.0
Xanomeline High Dose		Week 6	130.0	136.0	-6.0
Xanomeline High Dose		Week 8	130.0	138.0	-8.0
Xanomeline High Dose		Week 8	128.0	142.0	-14.0
Xanomeline High Dose		Week 8	126.0	136.0	-10.0
Xanomeline High Dose			132.0	138.0
Xanomeline High Dose			136.0	142.0
Xanomeline High Dose			134.0	136.0
Xanomeline High Dose			138.0	138.0
Xanomeline High Dose			130.0	142.0
Xanomeline High Dose			132.0	136.0
Placebo		Week 12	130.0	108.0	22.0
Placebo		Week 12	128.0	100.0	28.0
Placebo		Week 12	136.0	102.0	34.0
Placebo		Week 16	130.0	108.0	22.0
Placebo		Week 16	128.0	100.0	28.0
Placebo		Week 16	128.0	102.0	26.0
Placebo		Week 2	96.0	108.0	-12.0
Placebo		Week 2	92.0	100.0	-8.0
Placebo		Week 2	90.0	102.0	-12.0
Placebo		Week 20	120.0	108.0	12.0
Placebo		Week 20	122.0	100.0	22.0
Placebo		Week 20	118.0	102.0	16.0
Placebo		Week 24	104.0	108.0	-4.0
Placebo		Week 24	108.0	100.0	8.0
Placebo		Week 24	104.0	102.0	2.0
Placebo		Week 26	88.0	108.0	-20.0
Placebo		Week 26	88.0	100.0	-12.0
Placebo		Week 26	88.0	102.0	-14.0
Placebo		Week 4	96.0	108.0	-12.0
Placebo		Week 4	90.0	100.0	-10.0
Placebo		Week 4	92.0	102.0	-10.0
Placebo		Week 6	102.0	108.0	-6.0
Placebo		Week 6	110.0	100.0	10.0
Placebo		Week 6	100.0	102.0	-2.0
Placebo		Week 8	112.0	108.0	4.0
Placebo		Week 8	110.0	100.0	10.0
Placebo		Week 8	100.0	102.0	-2.0
Placebo			110.0	108.0
Placebo			102.0	100.0
Placebo			104.0	102.0
Placebo			110.0	108.0
Placebo			98.0	100.0
Placebo			104.0	102.0
Xanomeline High Dose		Week 2	124.0	130.0	-6.0
Xanomeline High Dose		Week 2	124.0	140.0	-16.0
Xanomeline High Dose		Week 2	120.0	130.0	-10.0
Xanomeline High Dose		Week 4	120.0	130.0	-10.0
Xanomeline High Dose		Week 4	122.0	140.0	-18.0
Xanomeline High Dose		Week 4	120.0	130.0	-10.0
Xanomeline High Dose			100.0	130.0
Xanomeline High Dose			102.0	140.0
Xanomeline High Dose			100.0	130.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			118.0	140.0
Xanomeline High Dose			118.0	130.0
Xanomeline Low Dose		Week 12	130.0	140.0	-10.0
Xanomeline Low Dose		Week 12	138.0	142.0	-4.0
Xanomeline Low Dose		Week 12	134.0	150.0	-16.0
Xanomeline Low Dose		Week 16	130.0	140.0	-10.0
Xanomeline Low Dose		Week 16	140.0	142.0	-2.0
Xanomeline Low Dose		Week 16	130.0	150.0	-20.0
Xanomeline Low Dose		Week 2	114.0	140.0	-26.0
Xanomeline Low Dose		Week 2	140.0	142.0	-2.0
Xanomeline Low Dose		Week 2	142.0	150.0	-8.0
Xanomeline Low Dose		Week 20	132.0	140.0	-8.0
Xanomeline Low Dose		Week 20	138.0	142.0	-4.0
Xanomeline Low Dose		Week 20	132.0	150.0	-18.0
Xanomeline Low Dose		Week 24	138.0	140.0	-2.0
Xanomeline Low Dose		Week 24	140.0	142.0	-2.0
Xanomeline Low Dose		Week 24	138.0	150.0	-12.0
Xanomeline Low Dose		Week 26	138.0	140.0	-2.0
Xanomeline Low Dose		Week 26	134.0	142.0	-8.0
Xanomeline Low Dose		Week 26	138.0	150.0	-12.0
Xanomeline Low Dose		Week 4	122.0	140.0	-18.0
Xanomeline Low Dose		Week 4	134.0	142.0	-8.0
Xanomeline Low Dose		Week 4	130.0	150.0	-20.0
Xanomeline Low Dose		Week 6	132.0	140.0	-8.0
Xanomeline Low Dose		Week 6	150.0	142.0	8.0
Xanomeline Low Dose		Week 6	140.0	150.0	-10.0
Xanomeline Low Dose		Week 8	140.0	140.0	0.0
Xanomeline Low Dose		Week 8	152.0	142.0	10.0
Xanomeline Low Dose		Week 8	160.0	150.0	10.0
Xanomeline Low Dose			120.0	140.0
Xanomeline Low Dose			138.0	142.0
Xanomeline Low Dose			140.0	150.0
Xanomeline Low Dose			124.0	140.0
Xanomeline Low Dose			122.0	142.0
Xanomeline Low Dose			128.0	150.0
Xanomeline High Dose		Week 12	140.0	150.0	-10.0
Xanomeline High Dose		Week 12	138.0	158.0	-20.0
Xanomeline High Dose		Week 12	138.0	160.0	-22.0
Xanomeline High Dose		Week 16	128.0	150.0	-22.0
Xanomeline High Dose		Week 16	136.0	158.0	-22.0
Xanomeline High Dose		Week 16	134.0	160.0	-26.0
Xanomeline High Dose		Week 2	140.0	150.0	-10.0
Xanomeline High Dose		Week 2	146.0	158.0	-12.0
Xanomeline High Dose		Week 2	145.0	160.0	-15.0
Xanomeline High Dose		Week 20	130.0	150.0	-20.0
Xanomeline High Dose		Week 20	130.0	158.0	-28.0
Xanomeline High Dose		Week 20	130.0	160.0	-30.0
Xanomeline High Dose		Week 24	118.0	150.0	-32.0
Xanomeline High Dose		Week 24	122.0	158.0	-36.0
Xanomeline High Dose		Week 24	120.0	160.0	-40.0
Xanomeline High Dose		Week 26	124.0	150.0	-26.0
Xanomeline High Dose		Week 26	126.0	158.0	-32.0
Xanomeline High Dose		Week 26	128.0	160.0	-32.0
Xanomeline High Dose		Week 4	140.0	150.0	-10.0
Xanomeline High Dose		Week 4	143.0	158.0	-15.0
Xanomeline High Dose		Week 4	142.0	160.0	-18.0
Xanomeline High Dose		Week 6	110.0	150.0	-40.0
Xanomeline High Dose		Week 6	118.0	158.0	-40.0
Xanomeline High Dose		Week 6	112.0	160.0	-48.0
Xanomeline High Dose		Week 8	116.0	150.0	-34.0
Xanomeline High Dose		Week 8	120.0	158.0	-38.0
Xanomeline High Dose		Week 8	122.0	160.0	-38.0
Xanomeline High Dose			142.0	150.0
Xanomeline High Dose			146.0	158.0
Xanomeline High Dose			152.0	160.0
Xanomeline High Dose			128.0	150.0
Xanomeline High Dose			130.0	158.0
Xanomeline High Dose			126.0	160.0
Xanomeline High Dose		Week 2	132.0	150.0	-18.0
Xanomeline High Dose		Week 4	128.0	150.0	-22.0
Xanomeline High Dose		Week 4	150.0	146.0	4.0
Xanomeline High Dose		Week 4	138.0	146.0	-8.0
Xanomeline High Dose			142.0	150.0
Xanomeline High Dose			140.0	146.0
Xanomeline High Dose			132.0	146.0
Xanomeline High Dose			134.0	150.0
Xanomeline High Dose			140.0	146.0
Xanomeline High Dose			136.0	146.0
Xanomeline Low Dose		Week 2	118.0	146.0	-28.0
Xanomeline Low Dose		Week 2	126.0	136.0	-10.0
Xanomeline Low Dose		Week 2	128.0	144.0	-16.0
Xanomeline Low Dose			124.0	146.0
Xanomeline Low Dose			140.0	136.0
Xanomeline Low Dose			148.0	144.0
Placebo		Week 12	144.0	162.0	-18.0
Placebo		Week 12	130.0	170.0	-40.0
Placebo		Week 12	132.0	168.0	-36.0
Placebo		Week 16	148.0	162.0	-14.0
Placebo		Week 16	134.0	170.0	-36.0
Placebo		Week 16	130.0	168.0	-38.0
Placebo		Week 2	134.0	162.0	-28.0
Placebo		Week 2	160.0	170.0	-10.0
Placebo		Week 2	146.0	168.0	-22.0
Placebo		Week 4	150.0	162.0	-12.0
Placebo		Week 4	156.0	170.0	-14.0
Placebo		Week 4	148.0	168.0	-20.0
Placebo		Week 6	160.0	162.0	-2.0
Placebo		Week 6	156.0	170.0	-14.0
Placebo		Week 6	158.0	168.0	-10.0
Placebo		Week 8	164.0	162.0	2.0
Placebo		Week 8	156.0	170.0	-14.0
Placebo		Week 8	152.0	168.0	-16.0
Placebo			124.0	162.0
Placebo			130.0	170.0
Placebo			134.0	168.0
Placebo			160.0	162.0
Placebo			156.0	170.0
Placebo			162.0	168.0
Xanomeline High Dose		Week 2	112.0	144.0	-32.0
Xanomeline High Dose		Week 2	106.0	120.0	-14.0
Xanomeline High Dose		Week 2	104.0	130.0	-26.0
Xanomeline High Dose		Week 4	124.0	144.0	-20.0
Xanomeline High Dose		Week 4	110.0	120.0	-10.0
Xanomeline High Dose		Week 4	106.0	130.0	-24.0
Xanomeline High Dose			134.0	144.0
Xanomeline High Dose			110.0	120.0
Xanomeline High Dose			116.0	130.0
Xanomeline Low Dose		Week 2	132.0	150.0	-18.0
Xanomeline Low Dose		Week 2	152.0	128.0	24.0
Xanomeline Low Dose		Week 2	156.0	142.0	14.0
Xanomeline Low Dose			132.0	150.0
Xanomeline Low Dose			150.0	128.0
Xanomeline Low Dose			152.0	142.0
Xanomeline High Dose		Week 2	142.0	142.0	0.0
Xanomeline High Dose		Week 2	144.0	146.0	-2.0
Xanomeline High Dose		Week 2	148.0	148.0	0.0
Xanomeline High Dose		Week 4	128.0	142.0	-14.0
Xanomeline High Dose		Week 4	140.0	146.0	-6.0
Xanomeline High Dose		Week 4	144.0	148.0	-4.0
Xanomeline High Dose		Week 6	122.0	142.0	-20.0
Xanomeline High Dose		Week 6	116.0	146.0	-30.0
Xanomeline High Dose		Week 6	114.0	148.0	-34.0
Xanomeline High Dose		Week 8	130.0	142.0	-12.0
Xanomeline High Dose		Week 8	124.0	146.0	-22.0
Xanomeline High Dose		Week 8	120.0	148.0	-28.0
Xanomeline High Dose			122.0	142.0
Xanomeline High Dose			128.0	146.0
Xanomeline High Dose			130.0	148.0
Xanomeline High Dose			116.0	142.0
Xanomeline High Dose			128.0	146.0
Xanomeline High Dose			124.0	148.0
Xanomeline High Dose		Week 2	152.0	170.0	-18.0
Xanomeline High Dose		Week 2	148.0	160.0	-12.0
Xanomeline High Dose		Week 2	156.0	170.0	-14.0
Xanomeline High Dose		Week 4	154.0	170.0	-16.0
Xanomeline High Dose		Week 4	150.0	160.0	-10.0
Xanomeline High Dose		Week 4	154.0	170.0	-16.0
Xanomeline High Dose		Week 6	156.0	170.0	-14.0
Xanomeline High Dose		Week 6	146.0	160.0	-14.0
Xanomeline High Dose		Week 6	150.0	170.0	-20.0
Xanomeline High Dose			166.0	170.0
Xanomeline High Dose			158.0	160.0
Xanomeline High Dose			176.0	170.0
Xanomeline High Dose			150.0	170.0
Xanomeline High Dose			154.0	160.0
Xanomeline High Dose			156.0	170.0
Xanomeline High Dose		Week 12	142.0	148.0	-6.0
Xanomeline High Dose		Week 12	156.0	152.0	4.0
Xanomeline High Dose		Week 12	144.0	148.0	-4.0
Xanomeline High Dose		Week 2	148.0	148.0	0.0
Xanomeline High Dose		Week 2	142.0	152.0	-10.0
Xanomeline High Dose		Week 2	142.0	148.0	-6.0
Xanomeline High Dose		Week 4	150.0	148.0	2.0
Xanomeline High Dose		Week 4	152.0	152.0	0.0
Xanomeline High Dose		Week 4	144.0	148.0	-4.0
Xanomeline High Dose		Week 6	156.0	148.0	8.0
Xanomeline High Dose		Week 6	144.0	152.0	-8.0
Xanomeline High Dose		Week 6	144.0	148.0	-4.0
Xanomeline High Dose		Week 8	158.0	148.0	10.0
Xanomeline High Dose		Week 8	152.0	152.0	0.0
Xanomeline High Dose		Week 8	152.0	148.0	4.0
Xanomeline High Dose			154.0	148.0
Xanomeline High Dose			158.0	152.0
Xanomeline High Dose			150.0	148.0
Xanomeline High Dose			152.0	148.0
Xanomeline High Dose			158.0	152.0
Xanomeline High Dose			148.0	148.0
Xanomeline Low Dose		Week 12	150.0	140.0	10.0
Xanomeline Low Dose		Week 12	132.0	132.0	0.0
Xanomeline Low Dose		Week 12	136.0	134.0	2.0
Xanomeline Low Dose		Week 16	154.0	140.0	14.0
Xanomeline Low Dose		Week 16	158.0	132.0	26.0
Xanomeline Low Dose		Week 16	152.0	134.0	18.0
Xanomeline Low Dose		Week 2	142.0	140.0	2.0
Xanomeline Low Dose		Week 2	130.0	132.0	-2.0
Xanomeline Low Dose		Week 2	140.0	134.0	6.0
Xanomeline Low Dose		Week 20	152.0	140.0	12.0
Xanomeline Low Dose		Week 20	158.0	132.0	26.0
Xanomeline Low Dose		Week 20	154.0	134.0	20.0
Xanomeline Low Dose		Week 4	144.0	140.0	4.0
Xanomeline Low Dose		Week 4	130.0	132.0	-2.0
Xanomeline Low Dose		Week 4	140.0	134.0	6.0
Xanomeline Low Dose		Week 6	132.0	140.0	-8.0
Xanomeline Low Dose		Week 6	136.0	132.0	4.0
Xanomeline Low Dose		Week 6	138.0	134.0	4.0
Xanomeline Low Dose		Week 8	138.0	140.0	-2.0
Xanomeline Low Dose		Week 8	144.0	132.0	12.0
Xanomeline Low Dose		Week 8	136.0	134.0	2.0
Xanomeline Low Dose			142.0	140.0
Xanomeline Low Dose			140.0	132.0
Xanomeline Low Dose			138.0	134.0
Xanomeline Low Dose			148.0	140.0
Xanomeline Low Dose			138.0	132.0
Xanomeline Low Dose			130.0	134.0
Xanomeline Low Dose		Week 2	142.0	132.0	10.0
Xanomeline Low Dose		Week 2	118.0	124.0	-6.0
Xanomeline Low Dose		Week 2	122.0	128.0	-6.0
Xanomeline Low Dose		Week 4	128.0	132.0	-4.0
Xanomeline Low Dose		Week 4	122.0	124.0	-2.0
Xanomeline Low Dose		Week 4	130.0	128.0	2.0
Xanomeline Low Dose		Week 6	130.0	132.0	-2.0
Xanomeline Low Dose		Week 6	132.0	124.0	8.0
Xanomeline Low Dose		Week 6	126.0	128.0	-2.0
Xanomeline Low Dose		Week 8	132.0	132.0	0.0
Xanomeline Low Dose		Week 8	128.0	124.0	4.0
Xanomeline Low Dose		Week 8	128.0	128.0	0.0
Xanomeline Low Dose			140.0	132.0
Xanomeline Low Dose			122.0	124.0
Xanomeline Low Dose			118.0	128.0
Xanomeline Low Dose			122.0	132.0
Xanomeline Low Dose			130.0	124.0
Xanomeline Low Dose			128.0	128.0
Placebo		Week 12	120.0	124.0	-4.0
Placebo		Week 12	108.0	132.0	-24.0
Placebo		Week 12	104.0	120.0	-16.0
Placebo		Week 16	124.0	124.0	0.0
Placebo		Week 16	110.0	132.0	-22.0
Placebo		Week 16	108.0	120.0	-12.0
Placebo		Week 2	114.0	124.0	-10.0
Placebo		Week 2	126.0	132.0	-6.0
Placebo		Week 2	128.0	120.0	8.0
Placebo		Week 20	126.0	124.0	2.0
Placebo		Week 20	112.0	132.0	-20.0
Placebo		Week 20	110.0	120.0	-10.0
Placebo		Week 24	118.0	124.0	-6.0
Placebo		Week 24	122.0	132.0	-10.0
Placebo		Week 24	120.0	120.0	0.0
Placebo		Week 26	118.0	124.0	-6.0
Placebo		Week 26	116.0	132.0	-16.0
Placebo		Week 26	122.0	120.0	2.0
Placebo		Week 4	122.0	124.0	-2.0
Placebo		Week 4	106.0	132.0	-26.0
Placebo		Week 4	118.0	120.0	-2.0
Placebo		Week 6	126.0	124.0	2.0
Placebo		Week 6	124.0	132.0	-8.0
Placebo		Week 6	120.0	120.0	0.0
Placebo		Week 8	114.0	124.0	-10.0
Placebo		Week 8	116.0	132.0	-16.0
Placebo		Week 8	116.0	120.0	-4.0
Placebo			110.0	124.0
Placebo			122.0	132.0
Placebo			122.0	120.0
Placebo			112.0	124.0
Placebo			104.0	132.0
Placebo			102.0	120.0
Xanomeline Low Dose		Week 12	132.0	140.0	-8.0
Xanomeline Low Dose		Week 12	118.0	122.0	-4.0
Xanomeline Low Dose		Week 12	120.0	126.0	-6.0
Xanomeline Low Dose		Week 16	130.0	140.0	-10.0
Xanomeline Low Dose		Week 16	126.0	122.0	4.0
Xanomeline Low Dose		Week 16	128.0	126.0	2.0
Xanomeline Low Dose		Week 2	136.0	140.0	-4.0
Xanomeline Low Dose		Week 2	130.0	122.0	8.0
Xanomeline Low Dose		Week 2	124.0	126.0	-2.0
Xanomeline Low Dose		Week 20	140.0	140.0	0.0
Xanomeline Low Dose		Week 20	128.0	122.0	6.0
Xanomeline Low Dose		Week 20	120.0	126.0	-6.0
Xanomeline Low Dose		Week 24	138.0	140.0	-2.0
Xanomeline Low Dose		Week 24	130.0	122.0	8.0
Xanomeline Low Dose		Week 24	128.0	126.0	2.0
Xanomeline Low Dose		Week 26	130.0	140.0	-10.0
Xanomeline Low Dose		Week 26	118.0	122.0	-4.0
Xanomeline Low Dose		Week 26	120.0	126.0	-6.0
Xanomeline Low Dose		Week 4	142.0	140.0	2.0
Xanomeline Low Dose		Week 4	132.0	122.0	10.0
Xanomeline Low Dose		Week 4	128.0	126.0	2.0
Xanomeline Low Dose		Week 6	140.0	140.0	0.0
Xanomeline Low Dose		Week 6	136.0	122.0	14.0
Xanomeline Low Dose		Week 6	140.0	126.0	14.0
Xanomeline Low Dose		Week 8	140.0	140.0	0.0
Xanomeline Low Dose		Week 8	132.0	122.0	10.0
Xanomeline Low Dose		Week 8	138.0	126.0	12.0
Xanomeline Low Dose			138.0	140.0
Xanomeline Low Dose			128.0	122.0
Xanomeline Low Dose			126.0	126.0
Xanomeline Low Dose			138.0	140.0
Xanomeline Low Dose			138.0	122.0
Xanomeline Low Dose			142.0	126.0
Placebo		Week 12	126.0	120.0	6.0
Placebo		Week 12	122.0	124.0	-2.0
Placebo		Week 12	124.0	130.0	-6.0
Placebo		Week 16	126.0	120.0	6.0
Placebo		Week 16	110.0	124.0	-14.0
Placebo		Week 16	110.0	130.0	-20.0
Placebo		Week 2	114.0	120.0	-6.0
Placebo		Week 2	104.0	124.0	-20.0
Placebo		Week 2	108.0	130.0	-22.0
Placebo		Week 20	130.0	120.0	10.0
Placebo		Week 20	124.0	124.0	0.0
Placebo		Week 20	126.0	130.0	-4.0
Placebo		Week 24	126.0	120.0	6.0
Placebo		Week 24	102.0	124.0	-22.0
Placebo		Week 24	108.0	130.0	-22.0
Placebo		Week 26	90.0	120.0	-30.0
Placebo		Week 26	84.0	124.0	-40.0
Placebo		Week 26	80.0	130.0	-50.0
Placebo		Week 4	108.0	120.0	-12.0
Placebo		Week 4	110.0	124.0	-14.0
Placebo		Week 4	114.0	130.0	-16.0
Placebo		Week 6	122.0	120.0	2.0
Placebo		Week 6	118.0	124.0	-6.0
Placebo		Week 6	122.0	130.0	-8.0
Placebo		Week 8	124.0	120.0	4.0
Placebo		Week 8	122.0	124.0	-2.0
Placebo		Week 8	120.0	130.0	-10.0
Placebo			118.0	120.0
Placebo			108.0	124.0
Placebo			114.0	130.0
Placebo			118.0	120.0
Placebo			114.0	124.0
Placebo			124.0	130.0
Xanomeline Low Dose		Week 12	166.0	138.0	28.0
Xanomeline Low Dose		Week 12	162.0	146.0	16.0
Xanomeline Low Dose		Week 12	150.0	142.0	8.0
Xanomeline Low Dose		Week 16	158.0	138.0	20.0
Xanomeline Low Dose		Week 16	160.0	146.0	14.0
Xanomeline Low Dose		Week 16	168.0	142.0	26.0
Xanomeline Low Dose		Week 2	140.0	138.0	2.0
Xanomeline Low Dose		Week 2	168.0	146.0	22.0
Xanomeline Low Dose		Week 2	166.0	142.0	24.0
Xanomeline Low Dose		Week 20	162.0	138.0	24.0
Xanomeline Low Dose		Week 20	160.0	146.0	14.0
Xanomeline Low Dose		Week 20	156.0	142.0	14.0
Xanomeline Low Dose		Week 24	158.0	138.0	20.0
Xanomeline Low Dose		Week 24	168.0	146.0	22.0
Xanomeline Low Dose		Week 24	164.0	142.0	22.0
Xanomeline Low Dose		Week 26	170.0	138.0	32.0
Xanomeline Low Dose		Week 26	158.0	146.0	12.0
Xanomeline Low Dose		Week 26	160.0	142.0	18.0
Xanomeline Low Dose		Week 4	140.0	138.0	2.0
Xanomeline Low Dose		Week 4	156.0	146.0	10.0
Xanomeline Low Dose		Week 4	152.0	142.0	10.0
Xanomeline Low Dose		Week 6	170.0	138.0	32.0
Xanomeline Low Dose		Week 6	162.0	146.0	16.0
Xanomeline Low Dose		Week 6	160.0	142.0	18.0
Xanomeline Low Dose		Week 8	154.0	138.0	16.0
Xanomeline Low Dose		Week 8	150.0	146.0	4.0
Xanomeline Low Dose		Week 8	150.0	142.0	8.0
Xanomeline Low Dose			140.0	138.0
Xanomeline Low Dose			150.0	146.0
Xanomeline Low Dose			160.0	142.0
Xanomeline Low Dose			146.0	138.0
Xanomeline Low Dose			152.0	146.0
Xanomeline Low Dose			150.0	142.0
Placebo		Week 2	150.0	146.0	4.0
Placebo		Week 2	144.0	146.0	-2.0
Placebo		Week 2	142.0	142.0	0.0
Placebo			160.0	146.0
Placebo			150.0	146.0
Placebo			160.0	142.0
Xanomeline High Dose		Week 2	130.0	122.0	8.0
Xanomeline High Dose		Week 2	132.0	118.0	14.0
Xanomeline High Dose		Week 2	128.0	118.0	10.0
Xanomeline High Dose		Week 4	146.0	122.0	24.0
Xanomeline High Dose		Week 4	142.0	118.0	24.0
Xanomeline High Dose		Week 4	136.0	118.0	18.0
Xanomeline High Dose		Week 6	136.0	122.0	14.0
Xanomeline High Dose		Week 6	122.0	118.0	4.0
Xanomeline High Dose		Week 6	140.0	118.0	22.0
Xanomeline High Dose			132.0	122.0
Xanomeline High Dose			126.0	118.0
Xanomeline High Dose			126.0	118.0
Xanomeline High Dose			134.0	122.0
Xanomeline High Dose			140.0	118.0
Xanomeline High Dose			136.0	118.0
Placebo		Week 2	128.0	148.0	-20.0
Placebo		Week 2	120.0	128.0	-8.0
Placebo		Week 2	126.0	130.0	-4.0
Placebo		Week 4	132.0	148.0	-16.0
Placebo		Week 4	122.0	128.0	-6.0
Placebo		Week 4	124.0	130.0	-6.0
Placebo		Week 6	148.0	148.0	0.0
Placebo		Week 6	124.0	128.0	-4.0
Placebo		Week 6	120.0	130.0	-10.0
Placebo		Week 8	146.0	148.0	-2.0
Placebo		Week 8	128.0	128.0	0.0
Placebo		Week 8	128.0	130.0	-2.0
Placebo			144.0	148.0
Placebo			128.0	128.0
Placebo			134.0	130.0
Placebo			130.0	148.0
Placebo			116.0	128.0
Placebo			114.0	130.0
Xanomeline High Dose		Week 2	126.0	120.0	6.0
Xanomeline High Dose		Week 2	118.0	122.0	-4.0
Xanomeline High Dose		Week 2	118.0	120.0	-2.0
Xanomeline High Dose		Week 4	124.0	120.0	4.0
Xanomeline High Dose		Week 4	120.0	122.0	-2.0
Xanomeline High Dose		Week 4	122.0	120.0	2.0
Xanomeline High Dose		Week 6	116.0	120.0	-4.0
Xanomeline High Dose		Week 6	128.0	122.0	6.0
Xanomeline High Dose		Week 6	124.0	120.0	4.0
Xanomeline High Dose		Week 8	138.0	120.0	18.0
Xanomeline High Dose		Week 8	130.0	122.0	8.0
Xanomeline High Dose		Week 8	126.0	120.0	6.0
Xanomeline High Dose			122.0	120.0
Xanomeline High Dose			122.0	122.0
Xanomeline High Dose			118.0	120.0
Xanomeline High Dose			124.0	120.0
Xanomeline High Dose			120.0	122.0
Xanomeline High Dose			126.0	120.0
Xanomeline Low Dose		Week 2	140.0	140.0	0.0
Xanomeline Low Dose		Week 2	136.0	144.0	-8.0
Xanomeline Low Dose		Week 2	138.0	142.0	-4.0
Xanomeline Low Dose		Week 4	128.0	140.0	-12.0
Xanomeline Low Dose		Week 4	120.0	144.0	-24.0
Xanomeline Low Dose		Week 4	130.0	142.0	-12.0
Xanomeline Low Dose			142.0	140.0
Xanomeline Low Dose			138.0	144.0
Xanomeline Low Dose			140.0	142.0
Xanomeline Low Dose		Week 2	108.0	110.0	-2.0
Xanomeline Low Dose		Week 2	122.0	128.0	-6.0
Xanomeline Low Dose		Week 2	126.0	132.0	-6.0
Xanomeline Low Dose		Week 4	114.0	110.0	4.0
Xanomeline Low Dose		Week 4	124.0	128.0	-4.0
Xanomeline Low Dose		Week 4	128.0	132.0	-4.0
Xanomeline Low Dose		Week 6	122.0	110.0	12.0
Xanomeline Low Dose		Week 6	126.0	128.0	-2.0
Xanomeline Low Dose		Week 6	124.0	132.0	-8.0
Xanomeline Low Dose		Week 8	124.0	110.0	14.0
Xanomeline Low Dose		Week 8	128.0	128.0	0.0
Xanomeline Low Dose		Week 8	124.0	132.0	-8.0
Xanomeline Low Dose			120.0	110.0
Xanomeline Low Dose			130.0	128.0
Xanomeline Low Dose			134.0	132.0
Xanomeline Low Dose			118.0	110.0
Xanomeline Low Dose			120.0	128.0
Xanomeline Low Dose			122.0	132.0
Xanomeline High Dose		Week 2	138.0	136.0	2.0
Xanomeline High Dose		Week 2	136.0	140.0	-4.0
Xanomeline High Dose		Week 2	130.0	150.0	-20.0
Xanomeline High Dose		Week 4	132.0	136.0	-4.0
Xanomeline High Dose		Week 4	144.0	140.0	4.0
Xanomeline High Dose		Week 4	140.0	150.0	-10.0
Xanomeline High Dose		Week 6	132.0	136.0	-4.0
Xanomeline High Dose		Week 6	138.0	140.0	-2.0
Xanomeline High Dose		Week 6	138.0	150.0	-12.0
Xanomeline High Dose		Week 8	140.0	136.0	4.0
Xanomeline High Dose		Week 8	136.0	140.0	-4.0
Xanomeline High Dose		Week 8	136.0	150.0	-14.0
Xanomeline High Dose			138.0	136.0
Xanomeline High Dose			146.0	140.0
Xanomeline High Dose			140.0	150.0
Xanomeline High Dose			126.0	136.0
Xanomeline High Dose			116.0	140.0
Xanomeline High Dose			128.0	150.0
Placebo		Week 12	122.0	128.0	-6.0
Placebo		Week 12	130.0	132.0	-2.0
Placebo		Week 12	128.0	132.0	-4.0
Placebo		Week 16	134.0	128.0	6.0
Placebo		Week 16	142.0	132.0	10.0
Placebo		Week 16	112.0	132.0	-20.0
Placebo		Week 2	132.0	128.0	4.0
Placebo		Week 2	140.0	132.0	8.0
Placebo		Week 2	134.0	132.0	2.0
Placebo		Week 20	134.0	128.0	6.0
Placebo		Week 20	142.0	132.0	10.0
Placebo		Week 20	134.0	132.0	2.0
Placebo		Week 24	128.0	128.0	0.0
Placebo		Week 24	140.0	132.0	8.0
Placebo		Week 24	120.0	132.0	-12.0
Placebo		Week 26	132.0	128.0	4.0
Placebo		Week 26	126.0	132.0	-6.0
Placebo		Week 26	130.0	132.0	-2.0
Placebo		Week 4	142.0	128.0	14.0
Placebo		Week 4	142.0	132.0	10.0
Placebo		Week 4	134.0	132.0	2.0
Placebo		Week 6	122.0	128.0	-6.0
Placebo		Week 6	118.0	132.0	-14.0
Placebo		Week 6	120.0	132.0	-12.0
Placebo		Week 8	130.0	128.0	2.0
Placebo		Week 8	128.0	132.0	-4.0
Placebo		Week 8	130.0	132.0	-2.0
Placebo			140.0	128.0
Placebo			142.0	132.0
Placebo			138.0	132.0
Placebo		Week 12	132.0	138.0	-6.0
Placebo		Week 12	134.0	126.0	8.0
Placebo		Week 12	138.0	130.0	8.0
Placebo		Week 16	124.0	138.0	-14.0
Placebo		Week 16	140.0	126.0	14.0
Placebo		Week 16	136.0	130.0	6.0
Placebo		Week 2	144.0	138.0	6.0
Placebo		Week 2	124.0	126.0	-2.0
Placebo		Week 2	128.0	130.0	-2.0
Placebo		Week 20	122.0	138.0	-16.0
Placebo		Week 20	128.0	126.0	2.0
Placebo		Week 20	126.0	130.0	-4.0
Placebo		Week 24	124.0	138.0	-14.0
Placebo		Week 24	130.0	126.0	4.0
Placebo		Week 24	122.0	130.0	-8.0
Placebo		Week 4	136.0	138.0	-2.0
Placebo		Week 4	128.0	126.0	2.0
Placebo		Week 4	130.0	130.0	0.0
Placebo		Week 6	130.0	138.0	-8.0
Placebo		Week 6	124.0	126.0	-2.0
Placebo		Week 6	128.0	130.0	-2.0
Placebo		Week 8	138.0	138.0	0.0
Placebo		Week 8	132.0	126.0	6.0
Placebo		Week 8	130.0	130.0	0.0
Placebo			136.0	138.0
Placebo			132.0	126.0
Placebo			130.0	130.0
Placebo			132.0	138.0
Placebo			120.0	126.0
Placebo			126.0	130.0
Placebo		Week 2	122.0	144.0	-22.0
Placebo		Week 2	108.0	118.0	-10.0
Placebo		Week 2	102.0	120.0	-18.0
Placebo		Week 4	130.0	144.0	-14.0
Placebo		Week 4	128.0	118.0	10.0
Placebo		Week 4	126.0	120.0	6.0
Placebo		Week 6	124.0	144.0	-20.0
Placebo		Week 6	118.0	118.0	0.0
Placebo		Week 6	120.0	120.0	0.0
Placebo			140.0	144.0
Placebo			130.0	118.0
Placebo			134.0	120.0
Placebo			120.0	144.0
Placebo			114.0	118.0
Placebo			116.0	120.0
Placebo		Week 12	126.0	116.0	10.0
Placebo		Week 12	128.0	120.0	8.0
Placebo		Week 12	132.0	126.0	6.0
Placebo		Week 16	160.0	116.0	44.0
Placebo		Week 16	140.0	120.0	20.0
Placebo		Week 16	142.0	126.0	16.0
Placebo		Week 2	124.0	116.0	8.0
Placebo		Week 2	128.0	120.0	8.0
Placebo		Week 2	130.0	126.0	4.0
Placebo		Week 20	152.0	116.0	36.0
Placebo		Week 20	136.0	120.0	16.0
Placebo		Week 20	118.0	126.0	-8.0
Placebo		Week 4	120.0	116.0	4.0
Placebo		Week 4	128.0	120.0	8.0
Placebo		Week 4	126.0	126.0	0.0
Placebo		Week 6	120.0	116.0	4.0
Placebo		Week 6	134.0	120.0	14.0
Placebo		Week 6	130.0	126.0	4.0
Placebo		Week 8	126.0	116.0	10.0
Placebo		Week 8	130.0	120.0	10.0
Placebo		Week 8	132.0	126.0	6.0
Placebo			122.0	116.0
Placebo			130.0	120.0
Placebo			132.0	126.0
Placebo			122.0	116.0
Placebo			130.0	120.0
Placebo			128.0	126.0
Xanomeline Low Dose		Week 2	120.0	138.0	-18.0
Xanomeline Low Dose		Week 2	115.0	134.0	-19.0
Xanomeline Low Dose		Week 2	115.0	134.0	-19.0
Xanomeline Low Dose			120.0	138.0
Xanomeline Low Dose			110.0	134.0
Xanomeline Low Dose			110.0	134.0
Placebo		Week 12	142.0	135.0	7.0
Placebo		Week 12	130.0	135.0	-5.0
Placebo		Week 12	142.0	135.0	7.0
Placebo		Week 16	120.0	135.0	-15.0
Placebo		Week 16	118.0	135.0	-17.0
Placebo		Week 16	118.0	135.0	-17.0
Placebo		Week 2	120.0	135.0	-15.0
Placebo		Week 2	125.0	135.0	-10.0
Placebo		Week 2	125.0	135.0	-10.0
Placebo		Week 4	140.0	135.0	5.0
Placebo		Week 4	136.0	135.0	1.0
Placebo		Week 4	138.0	135.0	3.0
Placebo		Week 6	150.0	135.0	15.0
Placebo		Week 6	140.0	135.0	5.0
Placebo		Week 6	140.0	135.0	5.0
Placebo		Week 8	140.0	135.0	5.0
Placebo		Week 8	135.0	135.0	0.0
Placebo		Week 8	135.0	135.0	0.0
Placebo			140.0	135.0
Placebo			140.0	135.0
Placebo			140.0	135.0
Placebo			120.0	135.0
Placebo			130.0	135.0
Placebo			130.0	135.0
Placebo		Week 2	150.0	140.0	10.0
Placebo		Week 2	135.0	135.0	0.0
Placebo		Week 2	140.0	135.0	5.0
Placebo			130.0	140.0
Placebo			130.0	135.0
Placebo			135.0	135.0
Xanomeline High Dose		Week 12	130.0	100.0	30.0
Xanomeline High Dose		Week 12	128.0	100.0	28.0
Xanomeline High Dose		Week 12	130.0	100.0	30.0
Xanomeline High Dose		Week 16	145.0	100.0	45.0
Xanomeline High Dose		Week 16	140.0	100.0	40.0
Xanomeline High Dose		Week 16	140.0	100.0	40.0
Xanomeline High Dose		Week 2	125.0	100.0	25.0
Xanomeline High Dose		Week 2	130.0	100.0	30.0
Xanomeline High Dose		Week 2	140.0	100.0	40.0
Xanomeline High Dose		Week 20	145.0	100.0	45.0
Xanomeline High Dose		Week 20	142.0	100.0	42.0
Xanomeline High Dose		Week 20	140.0	100.0	40.0
Xanomeline High Dose		Week 24	118.0	100.0	18.0
Xanomeline High Dose		Week 24	116.0	100.0	16.0
Xanomeline High Dose		Week 24	120.0	100.0	20.0
Xanomeline High Dose		Week 26	130.0	100.0	30.0
Xanomeline High Dose		Week 26	130.0	100.0	30.0
Xanomeline High Dose		Week 26	130.0	100.0	30.0
Xanomeline High Dose		Week 4	140.0	100.0	40.0
Xanomeline High Dose		Week 4	139.0	100.0	39.0
Xanomeline High Dose		Week 4	138.0	100.0	38.0
Xanomeline High Dose		Week 6	140.0	100.0	40.0
Xanomeline High Dose		Week 6	130.0	100.0	30.0
Xanomeline High Dose		Week 6	144.0	100.0	44.0
Xanomeline High Dose		Week 8	150.0	100.0	50.0
Xanomeline High Dose		Week 8	145.0	100.0	45.0
Xanomeline High Dose		Week 8	150.0	100.0	50.0
Xanomeline High Dose			120.0	100.0
Xanomeline High Dose			120.0	100.0
Xanomeline High Dose			120.0	100.0
Xanomeline High Dose			140.0	100.0
Xanomeline High Dose			130.0	100.0
Xanomeline High Dose			130.0	100.0
Xanomeline High Dose		Week 12	138.0	160.0	-22.0
Xanomeline High Dose		Week 12	144.0	150.0	-6.0
Xanomeline High Dose		Week 12	144.0	150.0	-6.0
Xanomeline High Dose		Week 2	160.0	160.0	0.0
Xanomeline High Dose		Week 2	165.0	150.0	15.0
Xanomeline High Dose		Week 2	160.0	150.0	10.0
Xanomeline High Dose		Week 4	144.0	160.0	-16.0
Xanomeline High Dose		Week 4	140.0	150.0	-10.0
Xanomeline High Dose		Week 4	140.0	150.0	-10.0
Xanomeline High Dose		Week 6	155.0	160.0	-5.0
Xanomeline High Dose		Week 6	150.0	150.0	0.0
Xanomeline High Dose		Week 6	165.0	150.0	15.0
Xanomeline High Dose		Week 8	170.0	160.0	10.0
Xanomeline High Dose		Week 8	150.0	150.0	0.0
Xanomeline High Dose		Week 8	150.0	150.0	0.0
Xanomeline High Dose			130.0	160.0
Xanomeline High Dose			128.0	150.0
Xanomeline High Dose			128.0	150.0
Xanomeline High Dose			142.0	160.0
Xanomeline High Dose			136.0	150.0
Xanomeline High Dose			136.0	150.0
Placebo		Week 12	138.0	120.0	18.0
Placebo		Week 12	144.0	120.0	24.0
Placebo		Week 12	144.0	120.0	24.0
Placebo		Week 16	110.0	120.0	-10.0
Placebo		Week 16	110.0	120.0	-10.0
Placebo		Week 16	110.0	120.0	-10.0
Placebo		Week 2	120.0	120.0	0.0
Placebo		Week 2	120.0	120.0	0.0
Placebo		Week 2	120.0	120.0	0.0
Placebo		Week 20	124.0	120.0	4.0
Placebo		Week 20	120.0	120.0	0.0
Placebo		Week 20	120.0	120.0	0.0
Placebo		Week 24	138.0	120.0	18.0
Placebo		Week 24	144.0	120.0	24.0
Placebo		Week 24	140.0	120.0	20.0
Placebo		Week 26	130.0	120.0	10.0
Placebo		Week 26	128.0	120.0	8.0
Placebo		Week 26	130.0	120.0	10.0
Placebo		Week 4	125.0	120.0	5.0
Placebo		Week 4	145.0	120.0	25.0
Placebo		Week 4	140.0	120.0	20.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 8	138.0	120.0	18.0
Placebo		Week 8	155.0	120.0	35.0
Placebo		Week 8	150.0	120.0	30.0
Placebo			138.0	120.0
Placebo			130.0	120.0
Placebo			128.0	120.0
Placebo			140.0	120.0
Placebo			130.0	120.0
Placebo			130.0	120.0
Xanomeline Low Dose		Week 12	140.0	110.0	30.0
Xanomeline Low Dose		Week 12	130.0	120.0	10.0
Xanomeline Low Dose		Week 12	130.0	120.0	10.0
Xanomeline Low Dose		Week 16	130.0	110.0	20.0
Xanomeline Low Dose		Week 16	126.0	120.0	6.0
Xanomeline Low Dose		Week 16	126.0	120.0	6.0
Xanomeline Low Dose		Week 2	138.0	110.0	28.0
Xanomeline Low Dose		Week 2	140.0	120.0	20.0
Xanomeline Low Dose		Week 2	140.0	120.0	20.0
Xanomeline Low Dose		Week 20	125.0	110.0	15.0
Xanomeline Low Dose		Week 20	130.0	120.0	10.0
Xanomeline Low Dose		Week 20	130.0	120.0	10.0
Xanomeline Low Dose		Week 24	140.0	110.0	30.0
Xanomeline Low Dose		Week 24	140.0	120.0	20.0
Xanomeline Low Dose		Week 24	140.0	120.0	20.0
Xanomeline Low Dose		Week 4	130.0	110.0	20.0
Xanomeline Low Dose		Week 4	125.0	120.0	5.0
Xanomeline Low Dose		Week 4	128.0	120.0	8.0
Xanomeline Low Dose		Week 6	125.0	110.0	15.0
Xanomeline Low Dose		Week 6	120.0	120.0	0.0
Xanomeline Low Dose		Week 6	120.0	120.0	0.0
Xanomeline Low Dose		Week 8	138.0	110.0	28.0
Xanomeline Low Dose		Week 8	155.0	120.0	35.0
Xanomeline Low Dose		Week 8	150.0	120.0	30.0
Xanomeline Low Dose			135.0	110.0
Xanomeline Low Dose			130.0	120.0
Xanomeline Low Dose			130.0	120.0
Xanomeline Low Dose			120.0	110.0
Xanomeline Low Dose			120.0	120.0
Xanomeline Low Dose			120.0	120.0
Xanomeline High Dose		Week 2	138.0	155.0	-17.0
Xanomeline High Dose		Week 2	130.0	160.0	-30.0
Xanomeline High Dose		Week 2	130.0	160.0	-30.0
Xanomeline High Dose			155.0	155.0
Xanomeline High Dose			150.0	160.0
Xanomeline High Dose			150.0	160.0
Xanomeline High Dose		Week 12	105.0	130.0	-25.0
Xanomeline High Dose		Week 12	100.0	120.0	-20.0
Xanomeline High Dose		Week 12	100.0	120.0	-20.0
Xanomeline High Dose		Week 2	140.0	130.0	10.0
Xanomeline High Dose		Week 2	130.0	120.0	10.0
Xanomeline High Dose		Week 2	130.0	120.0	10.0
Xanomeline High Dose		Week 4	140.0	130.0	10.0
Xanomeline High Dose		Week 4	135.0	120.0	15.0
Xanomeline High Dose		Week 4	135.0	120.0	15.0
Xanomeline High Dose		Week 6	160.0	130.0	30.0
Xanomeline High Dose		Week 6	145.0	120.0	25.0
Xanomeline High Dose		Week 6	148.0	120.0	28.0
Xanomeline High Dose		Week 8	155.0	130.0	25.0
Xanomeline High Dose		Week 8	130.0	120.0	10.0
Xanomeline High Dose		Week 8	135.0	120.0	15.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			120.0	120.0
Xanomeline High Dose			120.0	120.0
Xanomeline High Dose			160.0	130.0
Xanomeline High Dose			136.0	120.0
Xanomeline High Dose			130.0	120.0
Placebo		Week 12	140.0	145.0	-5.0
Placebo		Week 12	130.0	140.0	-10.0
Placebo		Week 12	130.0	140.0	-10.0
Placebo		Week 16	130.0	145.0	-15.0
Placebo		Week 16	130.0	140.0	-10.0
Placebo		Week 16	130.0	140.0	-10.0
Placebo		Week 2	148.0	145.0	3.0
Placebo		Week 2	130.0	140.0	-10.0
Placebo		Week 2	130.0	140.0	-10.0
Placebo		Week 20	150.0	145.0	5.0
Placebo		Week 20	145.0	140.0	5.0
Placebo		Week 20	145.0	140.0	5.0
Placebo		Week 24	140.0	145.0	-5.0
Placebo		Week 24	138.0	140.0	-2.0
Placebo		Week 24	135.0	140.0	-5.0
Placebo		Week 26	140.0	145.0	-5.0
Placebo		Week 26	135.0	140.0	-5.0
Placebo		Week 26	130.0	140.0	-10.0
Placebo		Week 4	120.0	145.0	-25.0
Placebo		Week 4	120.0	140.0	-20.0
Placebo		Week 4	120.0	140.0	-20.0
Placebo		Week 6	126.0	145.0	-19.0
Placebo		Week 6	120.0	140.0	-20.0
Placebo		Week 6	125.0	140.0	-15.0
Placebo		Week 8	165.0	145.0	20.0
Placebo		Week 8	160.0	140.0	20.0
Placebo		Week 8	160.0	140.0	20.0
Placebo			140.0	145.0
Placebo			130.0	140.0
Placebo			130.0	140.0
Xanomeline High Dose		Week 2	120.0	105.0	15.0
Xanomeline High Dose		Week 2	128.0	110.0	18.0
Xanomeline High Dose		Week 2	124.0	110.0	14.0
Xanomeline High Dose			120.0	105.0
Xanomeline High Dose			120.0	110.0
Xanomeline High Dose			120.0	110.0
Xanomeline Low Dose		Week 12	170.0	160.0	10.0
Xanomeline Low Dose		Week 12	168.0	155.0	13.0
Xanomeline Low Dose		Week 12	170.0	155.0	15.0
Xanomeline Low Dose		Week 16	165.0	160.0	5.0
Xanomeline Low Dose		Week 16	160.0	155.0	5.0
Xanomeline Low Dose		Week 16	160.0	155.0	5.0
Xanomeline Low Dose		Week 2	120.0	160.0	-40.0
Xanomeline Low Dose		Week 2	120.0	155.0	-35.0
Xanomeline Low Dose		Week 2	120.0	155.0	-35.0
Xanomeline Low Dose		Week 4	130.0	160.0	-30.0
Xanomeline Low Dose		Week 4	130.0	155.0	-25.0
Xanomeline Low Dose		Week 4	130.0	155.0	-25.0
Xanomeline Low Dose		Week 6	195.0	160.0	35.0
Xanomeline Low Dose		Week 6	180.0	155.0	25.0
Xanomeline Low Dose		Week 6	180.0	155.0	25.0
Xanomeline Low Dose		Week 8	130.0	160.0	-30.0
Xanomeline Low Dose		Week 8	150.0	155.0	-5.0
Xanomeline Low Dose		Week 8	140.0	155.0	-15.0
Xanomeline Low Dose			140.0	160.0
Xanomeline Low Dose			140.0	155.0
Xanomeline Low Dose			140.0	155.0
Xanomeline Low Dose			140.0	160.0
Xanomeline Low Dose			140.0	155.0
Xanomeline Low Dose			140.0	155.0
Xanomeline Low Dose		Week 12	125.0	145.0	-20.0
Xanomeline Low Dose		Week 12	110.0	140.0	-30.0
Xanomeline Low Dose		Week 12	105.0	140.0	-35.0
Xanomeline Low Dose		Week 16	125.0	145.0	-20.0
Xanomeline Low Dose		Week 16	120.0	140.0	-20.0
Xanomeline Low Dose		Week 16	120.0	140.0	-20.0
Xanomeline Low Dose		Week 2	114.0	145.0	-31.0
Xanomeline Low Dose		Week 2	118.0	140.0	-22.0
Xanomeline Low Dose		Week 2	116.0	140.0	-24.0
Xanomeline Low Dose		Week 20	130.0	145.0	-15.0
Xanomeline Low Dose		Week 20	130.0	140.0	-10.0
Xanomeline Low Dose		Week 20	130.0	140.0	-10.0
Xanomeline Low Dose		Week 24	110.0	145.0	-35.0
Xanomeline Low Dose		Week 24	110.0	140.0	-30.0
Xanomeline Low Dose		Week 24	110.0	140.0	-30.0
Xanomeline Low Dose		Week 26	110.0	145.0	-35.0
Xanomeline Low Dose		Week 26	105.0	140.0	-35.0
Xanomeline Low Dose		Week 26	105.0	140.0	-35.0
Xanomeline Low Dose		Week 4	110.0	145.0	-35.0
Xanomeline Low Dose		Week 4	110.0	140.0	-30.0
Xanomeline Low Dose		Week 4	110.0	140.0	-30.0
Xanomeline Low Dose		Week 6	138.0	145.0	-7.0
Xanomeline Low Dose		Week 6	128.0	140.0	-12.0
Xanomeline Low Dose		Week 6	126.0	140.0	-14.0
Xanomeline Low Dose		Week 8	100.0	145.0	-45.0
Xanomeline Low Dose		Week 8	100.0	140.0	-40.0
Xanomeline Low Dose		Week 8	100.0	140.0	-40.0
Xanomeline Low Dose			128.0	145.0
Xanomeline Low Dose			125.0	140.0
Xanomeline Low Dose			125.0	140.0
Xanomeline Low Dose			120.0	145.0
Xanomeline Low Dose			110.0	140.0
Xanomeline Low Dose			110.0	140.0
Placebo		Week 12	156.0	142.0	14.0
Placebo		Week 12	130.0	138.0	-8.0
Placebo		Week 12	133.0	136.0	-3.0
Placebo		Week 16	146.0	142.0	4.0
Placebo		Week 16	158.0	138.0	20.0
Placebo		Week 16	150.0	136.0	14.0
Placebo		Week 2	146.0	142.0	4.0
Placebo		Week 2	140.0	138.0	2.0
Placebo		Week 2	130.0	136.0	-6.0
Placebo		Week 20	178.0	142.0	36.0
Placebo		Week 20	186.0	138.0	48.0
Placebo		Week 20	158.0	136.0	22.0
Placebo		Week 24	154.0	142.0	12.0
Placebo		Week 24	156.0	138.0	18.0
Placebo		Week 24	166.0	136.0	30.0
Placebo		Week 4	160.0	142.0	18.0
Placebo		Week 4	150.0	138.0	12.0
Placebo		Week 4	150.0	136.0	14.0
Placebo		Week 6	158.0	142.0	16.0
Placebo		Week 6	150.0	138.0	12.0
Placebo		Week 6	158.0	136.0	22.0
Placebo		Week 8	150.0	142.0	8.0
Placebo		Week 8	140.0	138.0	2.0
Placebo		Week 8	142.0	136.0	6.0
Placebo			142.0	142.0
Placebo			138.0	138.0
Placebo			138.0	136.0
Placebo			162.0	142.0
Placebo			158.0	138.0
Placebo			160.0	136.0
Xanomeline High Dose		Week 2	138.0	120.0	18.0
Xanomeline High Dose		Week 2	130.0	118.0	12.0
Xanomeline High Dose		Week 2	128.0	112.0	16.0
Xanomeline High Dose		Week 4	140.0	120.0	20.0
Xanomeline High Dose		Week 4	120.0	118.0	2.0
Xanomeline High Dose		Week 4	118.0	112.0	6.0
Xanomeline High Dose			128.0	120.0
Xanomeline High Dose			120.0	118.0
Xanomeline High Dose			118.0	112.0
Xanomeline High Dose			126.0	120.0
Xanomeline High Dose			110.0	118.0
Xanomeline High Dose			108.0	112.0
Placebo		Week 12	136.0	142.0	-6.0
Placebo		Week 12	132.0	134.0	-2.0
Placebo		Week 12	130.0	110.0	20.0
Placebo		Week 16	130.0	142.0	-12.0
Placebo		Week 16	120.0	134.0	-14.0
Placebo		Week 16	122.0	110.0	12.0
Placebo		Week 2	110.0	142.0	-32.0
Placebo		Week 2	108.0	134.0	-26.0
Placebo		Week 2	100.0	110.0	-10.0
Placebo		Week 20	130.0	142.0	-12.0
Placebo		Week 20	110.0	134.0	-24.0
Placebo		Week 20	100.0	110.0	-10.0
Placebo		Week 24	130.0	142.0	-12.0
Placebo		Week 24	128.0	134.0	-6.0
Placebo		Week 24	114.0	110.0	4.0
Placebo		Week 4	110.0	142.0	-32.0
Placebo		Week 4	108.0	134.0	-26.0
Placebo		Week 4	112.0	110.0	2.0
Placebo		Week 6	138.0	142.0	-4.0
Placebo		Week 6	130.0	134.0	-4.0
Placebo		Week 6	146.0	110.0	36.0
Placebo		Week 8	140.0	142.0	-2.0
Placebo		Week 8	132.0	134.0	-2.0
Placebo		Week 8	134.0	110.0	24.0
Placebo			120.0	142.0
Placebo			110.0	134.0
Placebo			114.0	110.0
Placebo			110.0	142.0
Placebo			108.0	134.0
Placebo			110.0	110.0
Xanomeline Low Dose		Week 2	132.0	120.0	12.0
Xanomeline Low Dose		Week 2	128.0	140.0	-12.0
Xanomeline Low Dose		Week 2	125.0	158.0	-33.0
Xanomeline Low Dose			135.0	120.0
Xanomeline Low Dose			135.0	140.0
Xanomeline Low Dose			132.0	158.0
Xanomeline Low Dose		Week 12	110.0	100.0	10.0
Xanomeline Low Dose		Week 12	110.0	100.0	10.0
Xanomeline Low Dose		Week 12	110.0	110.0	0.0
Xanomeline Low Dose		Week 16	110.0	100.0	10.0
Xanomeline Low Dose		Week 16	106.0	100.0	6.0
Xanomeline Low Dose		Week 16	100.0	110.0	-10.0
Xanomeline Low Dose		Week 2	120.0	100.0	20.0
Xanomeline Low Dose		Week 2	105.0	100.0	5.0
Xanomeline Low Dose		Week 2	110.0	110.0	0.0
Xanomeline Low Dose		Week 20	116.0	100.0	16.0
Xanomeline Low Dose		Week 20	118.0	100.0	18.0
Xanomeline Low Dose		Week 20	124.0	110.0	14.0
Xanomeline Low Dose		Week 24	110.0	100.0	10.0
Xanomeline Low Dose		Week 24	110.0	100.0	10.0
Xanomeline Low Dose		Week 24	100.0	110.0	-10.0
Xanomeline Low Dose		Week 26	104.0	100.0	4.0
Xanomeline Low Dose		Week 26	108.0	100.0	8.0
Xanomeline Low Dose		Week 26	110.0	110.0	0.0
Xanomeline Low Dose		Week 4	120.0	100.0	20.0
Xanomeline Low Dose		Week 4	130.0	100.0	30.0
Xanomeline Low Dose		Week 4	130.0	110.0	20.0
Xanomeline Low Dose		Week 6	106.0	100.0	6.0
Xanomeline Low Dose		Week 6	118.0	100.0	18.0
Xanomeline Low Dose		Week 6	110.0	110.0	0.0
Xanomeline Low Dose		Week 8	110.0	100.0	10.0
Xanomeline Low Dose		Week 8	92.0	100.0	-8.0
Xanomeline Low Dose		Week 8	100.0	110.0	-10.0
Xanomeline Low Dose			90.0	100.0
Xanomeline Low Dose			100.0	100.0
Xanomeline Low Dose			100.0	110.0
Xanomeline Low Dose			128.0	100.0
Xanomeline Low Dose			100.0	100.0
Xanomeline Low Dose			110.0	110.0
Placebo		Week 12	160.0	170.0	-10.0
Placebo		Week 12	160.0	150.0	10.0
Placebo		Week 12	160.0	170.0	-10.0
Placebo		Week 16	162.0	170.0	-8.0
Placebo		Week 16	150.0	150.0	0.0
Placebo		Week 16	162.0	170.0	-8.0
Placebo		Week 2	168.0	170.0	-2.0
Placebo		Week 2	168.0	150.0	18.0
Placebo		Week 2	164.0	170.0	-6.0
Placebo		Week 20	160.0	170.0	-10.0
Placebo		Week 20	142.0	150.0	-8.0
Placebo		Week 20	138.0	170.0	-32.0
Placebo		Week 24	160.0	170.0	-10.0
Placebo		Week 24	140.0	150.0	-10.0
Placebo		Week 24	150.0	170.0	-20.0
Placebo		Week 26	124.0	170.0	-46.0
Placebo		Week 26	134.0	150.0	-16.0
Placebo		Week 26	152.0	170.0	-18.0
Placebo		Week 4	142.0	170.0	-28.0
Placebo		Week 4	140.0	150.0	-10.0
Placebo		Week 4	145.0	170.0	-25.0
Placebo		Week 6	150.0	170.0	-20.0
Placebo		Week 6	148.0	150.0	-2.0
Placebo		Week 6	148.0	170.0	-22.0
Placebo		Week 8	130.0	170.0	-40.0
Placebo		Week 8	130.0	150.0	-20.0
Placebo		Week 8	140.0	170.0	-30.0
Placebo			138.0	170.0
Placebo			140.0	150.0
Placebo			148.0	170.0
Placebo		Week 2	132.0	142.0	-10.0
Placebo		Week 2	130.0	120.0	10.0
Placebo		Week 2	130.0	144.0	-14.0
Placebo		Week 4	182.0	142.0	40.0
Placebo		Week 4	168.0	120.0	48.0
Placebo		Week 4	164.0	144.0	20.0
Placebo			170.0	142.0
Placebo			168.0	120.0
Placebo			168.0	144.0
Placebo			158.0	142.0
Placebo			140.0	120.0
Placebo			148.0	144.0
Placebo		Week 12	140.0	160.0	-20.0
Placebo		Week 12	140.0	150.0	-10.0
Placebo		Week 12	138.0	150.0	-12.0
Placebo		Week 16	142.0	160.0	-18.0
Placebo		Week 16	130.0	150.0	-20.0
Placebo		Week 16	140.0	150.0	-10.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 2	170.0	150.0	20.0
Placebo		Week 2	170.0	150.0	20.0
Placebo		Week 20	140.0	160.0	-20.0
Placebo		Week 20	128.0	150.0	-22.0
Placebo		Week 20	138.0	150.0	-12.0
Placebo		Week 24	140.0	160.0	-20.0
Placebo		Week 24	150.0	150.0	0.0
Placebo		Week 24	150.0	150.0	0.0
Placebo		Week 26	166.0	160.0	6.0
Placebo		Week 26	158.0	150.0	8.0
Placebo		Week 26	176.0	150.0	26.0
Placebo		Week 4	160.0	160.0	0.0
Placebo		Week 4	150.0	150.0	0.0
Placebo		Week 4	150.0	150.0	0.0
Placebo		Week 6	160.0	160.0	0.0
Placebo		Week 6	150.0	150.0	0.0
Placebo		Week 6	164.0	150.0	14.0
Placebo		Week 8	144.0	160.0	-16.0
Placebo		Week 8	160.0	150.0	10.0
Placebo		Week 8	158.0	150.0	8.0
Placebo			168.0	160.0
Placebo			172.0	150.0
Placebo			168.0	150.0
Placebo			140.0	160.0
Placebo			136.0	150.0
Placebo			140.0	150.0
Xanomeline High Dose		Week 12	150.0	142.0	8.0
Xanomeline High Dose		Week 12	140.0	130.0	10.0
Xanomeline High Dose		Week 12	140.0	134.0	6.0
Xanomeline High Dose		Week 2	128.0	142.0	-14.0
Xanomeline High Dose		Week 2	132.0	130.0	2.0
Xanomeline High Dose		Week 2	132.0	134.0	-2.0
Xanomeline High Dose		Week 4	110.0	142.0	-32.0
Xanomeline High Dose		Week 4	130.0	130.0	0.0
Xanomeline High Dose		Week 4	130.0	134.0	-4.0
Xanomeline High Dose		Week 6	130.0	142.0	-12.0
Xanomeline High Dose		Week 6	120.0	130.0	-10.0
Xanomeline High Dose		Week 6	120.0	134.0	-14.0
Xanomeline High Dose		Week 8	120.0	142.0	-22.0
Xanomeline High Dose		Week 8	116.0	130.0	-14.0
Xanomeline High Dose		Week 8	118.0	134.0	-16.0
Xanomeline High Dose			160.0	142.0
Xanomeline High Dose			160.0	130.0
Xanomeline High Dose			156.0	134.0
Xanomeline High Dose			120.0	142.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			140.0	134.0
Xanomeline Low Dose		Week 2	153.0	184.0	-31.0
Xanomeline Low Dose		Week 2	182.0	194.0	-12.0
Xanomeline Low Dose		Week 2	156.0	184.0	-28.0
Xanomeline High Dose		Week 2	140.0	150.0	-10.0
Xanomeline High Dose		Week 2	130.0	160.0	-30.0
Xanomeline High Dose		Week 2	130.0	158.0	-28.0
Xanomeline High Dose		Week 4	155.0	150.0	5.0
Xanomeline High Dose		Week 4	150.0	160.0	-10.0
Xanomeline High Dose		Week 4	150.0	158.0	-8.0
Xanomeline High Dose			160.0	150.0
Xanomeline High Dose			150.0	160.0
Xanomeline High Dose			158.0	158.0
Xanomeline High Dose			130.0	150.0
Xanomeline High Dose			123.0	160.0
Xanomeline High Dose			146.0	158.0
Placebo		Week 12	150.0	132.0	18.0
Placebo		Week 12	140.0	133.0	7.0
Placebo		Week 12	144.0	134.0	10.0
Placebo		Week 16	178.0	132.0	46.0
Placebo		Week 16	170.0	133.0	37.0
Placebo		Week 16	176.0	134.0	42.0
Placebo		Week 2	130.0	132.0	-2.0
Placebo		Week 2	150.0	133.0	17.0
Placebo		Week 2	128.0	134.0	-6.0
Placebo		Week 20	150.0	132.0	18.0
Placebo		Week 20	150.0	133.0	17.0
Placebo		Week 20	154.0	134.0	20.0
Placebo		Week 24	140.0	132.0	8.0
Placebo		Week 24	130.0	133.0	-3.0
Placebo		Week 24	130.0	134.0	-4.0
Placebo		Week 26	150.0	132.0	18.0
Placebo		Week 26	148.0	133.0	15.0
Placebo		Week 26	148.0	134.0	14.0
Placebo		Week 4	140.0	132.0	8.0
Placebo		Week 4	134.0	133.0	1.0
Placebo		Week 4	140.0	134.0	6.0
Placebo		Week 6	140.0	132.0	8.0
Placebo		Week 6	138.0	133.0	5.0
Placebo		Week 6	130.0	134.0	-4.0
Placebo		Week 8	140.0	132.0	8.0
Placebo		Week 8	140.0	133.0	7.0
Placebo		Week 8	138.0	134.0	4.0
Placebo			140.0	132.0
Placebo			150.0	133.0
Placebo			150.0	134.0
Placebo			140.0	132.0
Placebo			130.0	133.0
Placebo			130.0	134.0
Xanomeline Low Dose		Week 2	126.0	172.0	-46.0
Xanomeline Low Dose		Week 2	130.0	172.0	-42.0
Xanomeline Low Dose		Week 2	140.0	182.0	-42.0
Xanomeline Low Dose		Week 4	154.0	172.0	-18.0
Xanomeline Low Dose		Week 4	170.0	172.0	-2.0
Xanomeline Low Dose		Week 4	160.0	182.0	-22.0
Xanomeline Low Dose		Week 6	150.0	172.0	-22.0
Xanomeline Low Dose		Week 6	150.0	172.0	-22.0
Xanomeline Low Dose		Week 6	162.0	182.0	-20.0
Xanomeline Low Dose			140.0	172.0
Xanomeline Low Dose			120.0	172.0
Xanomeline Low Dose			160.0	182.0
Xanomeline Low Dose			150.0	172.0
Xanomeline Low Dose			144.0	172.0
Xanomeline Low Dose			140.0	182.0
Placebo		Week 12	158.0	142.0	16.0
Placebo		Week 12	128.0	128.0	0.0
Placebo		Week 12	144.0	142.0	2.0
Placebo		Week 16	140.0	142.0	-2.0
Placebo		Week 16	136.0	128.0	8.0
Placebo		Week 16	190.0	142.0	48.0
Placebo		Week 2	142.0	142.0	0.0
Placebo		Week 2	122.0	128.0	-6.0
Placebo		Week 2	144.0	142.0	2.0
Placebo		Week 20	142.0	142.0	0.0
Placebo		Week 20	146.0	128.0	18.0
Placebo		Week 20	132.0	142.0	-10.0
Placebo		Week 24	126.0	142.0	-16.0
Placebo		Week 24	130.0	128.0	2.0
Placebo		Week 24	130.0	142.0	-12.0
Placebo		Week 26	138.0	142.0	-4.0
Placebo		Week 26	134.0	128.0	6.0
Placebo		Week 26	138.0	142.0	-4.0
Placebo		Week 4	130.0	142.0	-12.0
Placebo		Week 4	114.0	128.0	-14.0
Placebo		Week 4	130.0	142.0	-12.0
Placebo		Week 6	140.0	142.0	-2.0
Placebo		Week 6	120.0	128.0	-8.0
Placebo		Week 6	138.0	142.0	-4.0
Placebo		Week 8	130.0	142.0	-12.0
Placebo		Week 8	120.0	128.0	-8.0
Placebo		Week 8	128.0	142.0	-14.0
Placebo			140.0	142.0
Placebo			118.0	128.0
Placebo			140.0	142.0
Placebo			130.0	142.0
Placebo			120.0	128.0
Placebo			130.0	142.0
Placebo		Week 12	132.0	140.0	-8.0
Placebo		Week 12	136.0	138.0	-2.0
Placebo		Week 12	144.0	140.0	4.0
Placebo		Week 16	126.0	140.0	-14.0
Placebo		Week 16	120.0	138.0	-18.0
Placebo		Week 16	130.0	140.0	-10.0
Placebo		Week 2	130.0	140.0	-10.0
Placebo		Week 2	120.0	138.0	-18.0
Placebo		Week 2	130.0	140.0	-10.0
Placebo		Week 20	144.0	140.0	4.0
Placebo		Week 20	138.0	138.0	0.0
Placebo		Week 20	138.0	140.0	-2.0
Placebo		Week 24	128.0	140.0	-12.0
Placebo		Week 24	114.0	138.0	-24.0
Placebo		Week 24	124.0	140.0	-16.0
Placebo		Week 26	140.0	140.0	0.0
Placebo		Week 26	138.0	138.0	0.0
Placebo		Week 26	130.0	140.0	-10.0
Placebo		Week 4	126.0	140.0	-14.0
Placebo		Week 4	130.0	138.0	-8.0
Placebo		Week 4	138.0	140.0	-2.0
Placebo		Week 6	130.0	140.0	-10.0
Placebo		Week 6	120.0	138.0	-18.0
Placebo		Week 6	130.0	140.0	-10.0
Placebo		Week 8	140.0	140.0	0.0
Placebo		Week 8	130.0	138.0	-8.0
Placebo		Week 8	130.0	140.0	-10.0
Placebo			140.0	140.0
Placebo			140.0	138.0
Placebo			140.0	140.0
Placebo			122.0	140.0
Placebo			118.0	138.0
Placebo			120.0	140.0
Xanomeline Low Dose		Week 12	128.0	132.0	-4.0
Xanomeline Low Dose		Week 12	120.0	120.0	0.0
Xanomeline Low Dose		Week 12	120.0	128.0	-8.0
Xanomeline Low Dose		Week 2	118.0	132.0	-14.0
Xanomeline Low Dose		Week 2	120.0	120.0	0.0
Xanomeline Low Dose		Week 2	120.0	128.0	-8.0
Xanomeline Low Dose		Week 4	160.0	132.0	28.0
Xanomeline Low Dose		Week 4	158.0	120.0	38.0
Xanomeline Low Dose		Week 4	140.0	128.0	12.0
Xanomeline Low Dose		Week 6	126.0	132.0	-6.0
Xanomeline Low Dose		Week 6	98.0	120.0	-22.0
Xanomeline Low Dose		Week 6	110.0	128.0	-18.0
Xanomeline Low Dose		Week 8	138.0	132.0	6.0
Xanomeline Low Dose		Week 8	130.0	120.0	10.0
Xanomeline Low Dose		Week 8	138.0	128.0	10.0
Xanomeline Low Dose			140.0	132.0
Xanomeline Low Dose			120.0	120.0
Xanomeline Low Dose			126.0	128.0
Xanomeline Low Dose			128.0	132.0
Xanomeline Low Dose			138.0	120.0
Xanomeline Low Dose			119.0	128.0
Placebo		Week 12	130.0	160.0	-30.0
Placebo		Week 12	130.0	160.0	-30.0
Placebo		Week 12	126.0	160.0	-34.0
Placebo		Week 16	130.0	160.0	-30.0
Placebo		Week 16	130.0	160.0	-30.0
Placebo		Week 16	130.0	160.0	-30.0
Placebo		Week 2	150.0	160.0	-10.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 20	144.0	160.0	-16.0
Placebo		Week 20	130.0	160.0	-30.0
Placebo		Week 20	140.0	160.0	-20.0
Placebo		Week 24	132.0	160.0	-28.0
Placebo		Week 24	130.0	160.0	-30.0
Placebo		Week 24	134.0	160.0	-26.0
Placebo		Week 26	170.0	160.0	10.0
Placebo		Week 26	130.0	160.0	-30.0
Placebo		Week 26	170.0	160.0	10.0
Placebo		Week 4	142.0	160.0	-18.0
Placebo		Week 4	142.0	160.0	-18.0
Placebo		Week 4	142.0	160.0	-18.0
Placebo		Week 6	142.0	160.0	-18.0
Placebo		Week 6	144.0	160.0	-16.0
Placebo		Week 6	154.0	160.0	-6.0
Placebo		Week 8	130.0	160.0	-30.0
Placebo		Week 8	140.0	160.0	-20.0
Placebo		Week 8	140.0	160.0	-20.0
Xanomeline High Dose		Week 12	130.0	130.0	0.0
Xanomeline High Dose		Week 12	124.0	130.0	-6.0
Xanomeline High Dose		Week 12	124.0	132.0	-8.0
Xanomeline High Dose		Week 16	140.0	130.0	10.0
Xanomeline High Dose		Week 16	130.0	130.0	0.0
Xanomeline High Dose		Week 16	130.0	132.0	-2.0
Xanomeline High Dose		Week 2	150.0	130.0	20.0
Xanomeline High Dose		Week 2	140.0	130.0	10.0
Xanomeline High Dose		Week 2	146.0	132.0	14.0
Xanomeline High Dose		Week 20	140.0	130.0	10.0
Xanomeline High Dose		Week 20	130.0	130.0	0.0
Xanomeline High Dose		Week 20	138.0	132.0	6.0
Xanomeline High Dose		Week 24	150.0	130.0	20.0
Xanomeline High Dose		Week 24	130.0	130.0	0.0
Xanomeline High Dose		Week 24	140.0	132.0	8.0
Xanomeline High Dose		Week 26	150.0	130.0	20.0
Xanomeline High Dose		Week 26	142.0	130.0	12.0
Xanomeline High Dose		Week 26	134.0	132.0	2.0
Xanomeline High Dose		Week 4	154.0	130.0	24.0
Xanomeline High Dose		Week 4	134.0	130.0	4.0
Xanomeline High Dose		Week 4	128.0	132.0	-4.0
Xanomeline High Dose		Week 6	140.0	130.0	10.0
Xanomeline High Dose		Week 6	130.0	130.0	0.0
Xanomeline High Dose		Week 6	130.0	132.0	-2.0
Xanomeline High Dose		Week 8	144.0	130.0	14.0
Xanomeline High Dose		Week 8	140.0	130.0	10.0
Xanomeline High Dose		Week 8	140.0	132.0	8.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			126.0	130.0
Xanomeline High Dose			130.0	132.0
Xanomeline High Dose			140.0	130.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			140.0	132.0
Placebo		Week 12	120.0	150.0	-30.0
Placebo		Week 12	130.0	160.0	-30.0
Placebo		Week 12	140.0	160.0	-20.0
Placebo		Week 16	140.0	150.0	-10.0
Placebo		Week 16	146.0	160.0	-14.0
Placebo		Week 16	150.0	160.0	-10.0
Placebo		Week 2	156.0	150.0	6.0
Placebo		Week 2	152.0	160.0	-8.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 20	110.0	150.0	-40.0
Placebo		Week 20	134.0	160.0	-26.0
Placebo		Week 20	144.0	160.0	-16.0
Placebo		Week 24	160.0	150.0	10.0
Placebo		Week 24	160.0	160.0	0.0
Placebo		Week 24	160.0	160.0	0.0
Placebo		Week 26	126.0	150.0	-24.0
Placebo		Week 26	142.0	160.0	-18.0
Placebo		Week 26	138.0	160.0	-22.0
Placebo		Week 4	152.0	150.0	2.0
Placebo		Week 4	160.0	160.0	0.0
Placebo		Week 4	158.0	160.0	-2.0
Placebo		Week 6	127.0	150.0	-23.0
Placebo		Week 6	140.0	160.0	-20.0
Placebo		Week 6	142.0	160.0	-18.0
Placebo		Week 8	140.0	150.0	-10.0
Placebo		Week 8	140.0	160.0	-20.0
Placebo		Week 8	136.0	160.0	-24.0
Placebo			180.0	150.0
Placebo			170.0	160.0
Placebo			170.0	160.0
Placebo			148.0	150.0
Placebo			148.0	160.0
Placebo			140.0	160.0
Xanomeline High Dose		Week 12	124.0	150.0	-26.0
Xanomeline High Dose		Week 12	140.0	120.0	20.0
Xanomeline High Dose		Week 12	130.0	140.0	-10.0
Xanomeline High Dose		Week 2	140.0	150.0	-10.0
Xanomeline High Dose		Week 2	142.0	120.0	22.0
Xanomeline High Dose		Week 2	140.0	140.0	0.0
Xanomeline High Dose		Week 4	110.0	150.0	-40.0
Xanomeline High Dose		Week 4	115.0	120.0	-5.0
Xanomeline High Dose		Week 4	112.0	140.0	-28.0
Xanomeline High Dose		Week 6	118.0	150.0	-32.0
Xanomeline High Dose		Week 6	122.0	120.0	2.0
Xanomeline High Dose		Week 6	126.0	140.0	-14.0
Xanomeline High Dose		Week 8	124.0	150.0	-26.0
Xanomeline High Dose		Week 8	120.0	120.0	0.0
Xanomeline High Dose		Week 8	130.0	140.0	-10.0
Xanomeline High Dose			162.0	150.0
Xanomeline High Dose			160.0	120.0
Xanomeline High Dose			162.0	140.0
Xanomeline High Dose			140.0	150.0
Xanomeline High Dose			140.0	120.0
Xanomeline High Dose			140.0	140.0
Xanomeline Low Dose		Week 12	140.0	140.0	0.0
Xanomeline Low Dose		Week 12	132.0	100.0	32.0
Xanomeline Low Dose		Week 12	134.0	110.0	24.0
Xanomeline Low Dose		Week 16	140.0	140.0	0.0
Xanomeline Low Dose		Week 16	130.0	100.0	30.0
Xanomeline Low Dose		Week 16	128.0	110.0	18.0
Xanomeline Low Dose		Week 2	140.0	140.0	0.0
Xanomeline Low Dose		Week 2	120.0	100.0	20.0
Xanomeline Low Dose		Week 2	120.0	110.0	10.0
Xanomeline Low Dose		Week 20	138.0	140.0	-2.0
Xanomeline Low Dose		Week 20	130.0	100.0	30.0
Xanomeline Low Dose		Week 20	128.0	110.0	18.0
Xanomeline Low Dose		Week 24	150.0	140.0	10.0
Xanomeline Low Dose		Week 24	126.0	100.0	26.0
Xanomeline Low Dose		Week 24	140.0	110.0	30.0
Xanomeline Low Dose		Week 26	134.0	140.0	-6.0
Xanomeline Low Dose		Week 26	116.0	100.0	16.0
Xanomeline Low Dose		Week 26	130.0	110.0	20.0
Xanomeline Low Dose		Week 4	180.0	140.0	40.0
Xanomeline Low Dose		Week 4	180.0	100.0	80.0
Xanomeline Low Dose		Week 4	168.0	110.0	58.0
Xanomeline Low Dose		Week 6	132.0	140.0	-8.0
Xanomeline Low Dose		Week 6	120.0	100.0	20.0
Xanomeline Low Dose		Week 6	130.0	110.0	20.0
Xanomeline Low Dose		Week 8	130.0	140.0	-10.0
Xanomeline Low Dose		Week 8	128.0	100.0	28.0
Xanomeline Low Dose		Week 8	130.0	110.0	20.0
Xanomeline Low Dose			130.0	140.0
Xanomeline Low Dose			124.0	100.0
Xanomeline Low Dose			140.0	110.0
Xanomeline Low Dose			150.0	140.0
Xanomeline Low Dose			120.0	100.0
Xanomeline Low Dose			140.0	110.0
Xanomeline Low Dose		Week 2	136.0	106.0	30.0
Xanomeline Low Dose		Week 2	140.0	106.0	34.0
Xanomeline Low Dose		Week 2	120.0	108.0	12.0
Xanomeline Low Dose		Week 4	112.0	106.0	6.0
Xanomeline Low Dose		Week 4	116.0	106.0	10.0
Xanomeline Low Dose		Week 4	110.0	108.0	2.0
Xanomeline Low Dose		Week 6	104.0	106.0	-2.0
Xanomeline Low Dose		Week 6	98.0	106.0	-8.0
Xanomeline Low Dose		Week 6	102.0	108.0	-6.0
Xanomeline Low Dose			104.0	106.0
Xanomeline Low Dose			98.0	106.0
Xanomeline Low Dose			104.0	108.0
Placebo		Week 12	118.0	122.0	-4.0
Placebo		Week 12	112.0	110.0	2.0
Placebo		Week 12	122.0	112.0	10.0
Placebo		Week 16	110.0	122.0	-12.0
Placebo		Week 16	108.0	110.0	-2.0
Placebo		Week 16	116.0	112.0	4.0
Placebo		Week 2	110.0	122.0	-12.0
Placebo		Week 2	110.0	110.0	0.0
Placebo		Week 2	110.0	112.0	-2.0
Placebo		Week 20	100.0	122.0	-22.0
Placebo		Week 20	124.0	110.0	14.0
Placebo		Week 20	90.0	112.0	-22.0
Placebo		Week 4	124.0	122.0	2.0
Placebo		Week 4	116.0	110.0	6.0
Placebo		Week 4	120.0	112.0	8.0
Placebo		Week 6	120.0	122.0	-2.0
Placebo		Week 6	118.0	110.0	8.0
Placebo		Week 6	120.0	112.0	8.0
Placebo		Week 8	120.0	122.0	-2.0
Placebo		Week 8	110.0	110.0	0.0
Placebo		Week 8	110.0	112.0	-2.0
Placebo			130.0	122.0
Placebo			120.0	110.0
Placebo			120.0	112.0
Xanomeline High Dose		Week 12	158.0	170.0	-12.0
Xanomeline High Dose		Week 12	152.0	170.0	-18.0
Xanomeline High Dose		Week 12	150.0	172.0	-22.0
Xanomeline High Dose		Week 16	152.0	170.0	-18.0
Xanomeline High Dose		Week 16	132.0	170.0	-38.0
Xanomeline High Dose		Week 16	130.0	172.0	-42.0
Xanomeline High Dose		Week 2	160.0	170.0	-10.0
Xanomeline High Dose		Week 2	160.0	170.0	-10.0
Xanomeline High Dose		Week 2	150.0	172.0	-22.0
Xanomeline High Dose		Week 20	142.0	170.0	-28.0
Xanomeline High Dose		Week 20	152.0	170.0	-18.0
Xanomeline High Dose		Week 20	152.0	172.0	-20.0
Xanomeline High Dose		Week 24	164.0	170.0	-6.0
Xanomeline High Dose		Week 24	168.0	170.0	-2.0
Xanomeline High Dose		Week 24	172.0	172.0	0.0
Xanomeline High Dose		Week 26	148.0	170.0	-22.0
Xanomeline High Dose		Week 26	130.0	170.0	-40.0
Xanomeline High Dose		Week 26	130.0	172.0	-42.0
Xanomeline High Dose		Week 4	160.0	170.0	-10.0
Xanomeline High Dose		Week 4	150.0	170.0	-20.0
Xanomeline High Dose		Week 4	160.0	172.0	-12.0
Xanomeline High Dose		Week 6	128.0	170.0	-42.0
Xanomeline High Dose		Week 6	140.0	170.0	-30.0
Xanomeline High Dose		Week 6	130.0	172.0	-42.0
Xanomeline High Dose		Week 8	150.0	170.0	-20.0
Xanomeline High Dose		Week 8	150.0	170.0	-20.0
Xanomeline High Dose		Week 8	150.0	172.0	-22.0
Xanomeline High Dose			150.0	170.0
Xanomeline High Dose			140.0	170.0
Xanomeline High Dose			150.0	172.0
Xanomeline High Dose			162.0	170.0
Xanomeline High Dose			150.0	170.0
Xanomeline High Dose			140.0	172.0
Xanomeline Low Dose		Week 2	180.0	156.0	24.0
Xanomeline Low Dose		Week 2	170.0	140.0	30.0
Xanomeline Low Dose		Week 2	180.0	140.0	40.0
Xanomeline Low Dose		Week 4	160.0	156.0	4.0
Xanomeline Low Dose		Week 4	160.0	140.0	20.0
Xanomeline Low Dose		Week 4	160.0	140.0	20.0
Xanomeline Low Dose			170.0	156.0
Xanomeline Low Dose			180.0	140.0
Xanomeline Low Dose			182.0	140.0
Xanomeline Low Dose			140.0	156.0
Xanomeline Low Dose			180.0	140.0
Xanomeline Low Dose			170.0	140.0
Placebo		Week 12	134.0	160.0	-26.0
Placebo		Week 12	130.0	170.0	-40.0
Placebo		Week 12	132.0	166.0	-34.0
Placebo		Week 16	152.0	160.0	-8.0
Placebo		Week 16	150.0	170.0	-20.0
Placebo		Week 16	150.0	166.0	-16.0
Placebo		Week 2	156.0	160.0	-4.0
Placebo		Week 2	146.0	170.0	-24.0
Placebo		Week 2	160.0	166.0	-6.0
Placebo		Week 20	154.0	160.0	-6.0
Placebo		Week 20	150.0	170.0	-20.0
Placebo		Week 20	150.0	166.0	-16.0
Placebo		Week 24	150.0	160.0	-10.0
Placebo		Week 24	140.0	170.0	-30.0
Placebo		Week 24	150.0	166.0	-16.0
Placebo		Week 26	140.0	160.0	-20.0
Placebo		Week 26	138.0	170.0	-32.0
Placebo		Week 26	140.0	166.0	-26.0
Placebo		Week 4	150.0	160.0	-10.0
Placebo		Week 4	142.0	170.0	-28.0
Placebo		Week 4	150.0	166.0	-16.0
Placebo		Week 6	142.0	160.0	-18.0
Placebo		Week 6	124.0	170.0	-46.0
Placebo		Week 6	150.0	166.0	-16.0
Placebo		Week 8	150.0	160.0	-10.0
Placebo		Week 8	142.0	170.0	-28.0
Placebo		Week 8	150.0	166.0	-16.0
Placebo			142.0	160.0
Placebo			150.0	170.0
Placebo			140.0	166.0
Placebo			124.0	160.0
Placebo			150.0	170.0
Placebo			160.0	166.0
Xanomeline Low Dose		Week 2	112.0	120.0	-8.0
Xanomeline Low Dose		Week 2	100.0	120.0	-20.0
Xanomeline Low Dose		Week 2	110.0	118.0	-8.0
Xanomeline Low Dose			118.0	120.0
Xanomeline Low Dose			110.0	120.0
Xanomeline Low Dose			120.0	118.0
Xanomeline Low Dose		Week 12	142.0	132.0	10.0
Xanomeline Low Dose		Week 12	132.0	150.0	-18.0
Xanomeline Low Dose		Week 12	140.0	150.0	-10.0
Xanomeline Low Dose		Week 16	138.0	132.0	6.0
Xanomeline Low Dose		Week 16	130.0	150.0	-20.0
Xanomeline Low Dose		Week 16	120.0	150.0	-30.0
Xanomeline Low Dose		Week 2	168.0	132.0	36.0
Xanomeline Low Dose		Week 2	158.0	150.0	8.0
Xanomeline Low Dose		Week 2	154.0	150.0	4.0
Xanomeline Low Dose		Week 20	128.0	132.0	-4.0
Xanomeline Low Dose		Week 20	122.0	150.0	-28.0
Xanomeline Low Dose		Week 20	124.0	150.0	-26.0
Xanomeline Low Dose		Week 24	150.0	132.0	18.0
Xanomeline Low Dose		Week 24	140.0	150.0	-10.0
Xanomeline Low Dose		Week 24	120.0	150.0	-30.0
Xanomeline Low Dose		Week 26	128.0	132.0	-4.0
Xanomeline Low Dose		Week 26	118.0	150.0	-32.0
Xanomeline Low Dose		Week 26	122.0	150.0	-28.0
Xanomeline Low Dose		Week 4	160.0	132.0	28.0
Xanomeline Low Dose		Week 4	148.0	150.0	-2.0
Xanomeline Low Dose		Week 4	132.0	150.0	-18.0
Xanomeline Low Dose		Week 6	130.0	132.0	-2.0
Xanomeline Low Dose		Week 6	128.0	150.0	-22.0
Xanomeline Low Dose		Week 6	126.0	150.0	-24.0
Xanomeline Low Dose		Week 8	142.0	132.0	10.0
Xanomeline Low Dose		Week 8	130.0	150.0	-20.0
Xanomeline Low Dose		Week 8	138.0	150.0	-12.0
Xanomeline High Dose		Week 12	130.0	144.0	-14.0
Xanomeline High Dose		Week 12	118.0	132.0	-14.0
Xanomeline High Dose		Week 12	126.0	140.0	-14.0
Xanomeline High Dose		Week 16	148.0	144.0	4.0
Xanomeline High Dose		Week 16	130.0	132.0	-2.0
Xanomeline High Dose		Week 16	134.0	140.0	-6.0
Xanomeline High Dose		Week 2	142.0	144.0	-2.0
Xanomeline High Dose		Week 2	130.0	132.0	-2.0
Xanomeline High Dose		Week 2	118.0	140.0	-22.0
Xanomeline High Dose		Week 20	122.0	144.0	-22.0
Xanomeline High Dose		Week 20	130.0	132.0	-2.0
Xanomeline High Dose		Week 20	122.0	140.0	-18.0
Xanomeline High Dose		Week 24	128.0	144.0	-16.0
Xanomeline High Dose		Week 24	124.0	132.0	-8.0
Xanomeline High Dose		Week 24	130.0	140.0	-10.0
Xanomeline High Dose		Week 26	124.0	144.0	-20.0
Xanomeline High Dose		Week 26	114.0	132.0	-18.0
Xanomeline High Dose		Week 26	106.0	140.0	-34.0
Xanomeline High Dose		Week 4	124.0	144.0	-20.0
Xanomeline High Dose		Week 4	140.0	132.0	8.0
Xanomeline High Dose		Week 4	134.0	140.0	-6.0
Xanomeline High Dose		Week 6	140.0	144.0	-4.0
Xanomeline High Dose		Week 6	118.0	132.0	-14.0
Xanomeline High Dose		Week 6	130.0	140.0	-10.0
Xanomeline High Dose		Week 8	132.0	144.0	-12.0
Xanomeline High Dose		Week 8	148.0	132.0	16.0
Xanomeline High Dose		Week 8	128.0	140.0	-12.0
Xanomeline High Dose			120.0	144.0
Xanomeline High Dose			150.0	132.0
Xanomeline High Dose			140.0	140.0
Xanomeline High Dose			140.0	144.0
Xanomeline High Dose			128.0	132.0
Xanomeline High Dose			120.0	140.0
Xanomeline Low Dose		Week 12	120.0	128.0	-8.0
Xanomeline Low Dose		Week 12	130.0	138.0	-8.0
Xanomeline Low Dose		Week 12	130.0	128.0	2.0
Xanomeline Low Dose		Week 2	140.0	128.0	12.0
Xanomeline Low Dose		Week 2	138.0	138.0	0.0
Xanomeline Low Dose		Week 2	136.0	128.0	8.0
Xanomeline Low Dose		Week 4	144.0	128.0	16.0
Xanomeline Low Dose		Week 4	136.0	138.0	-2.0
Xanomeline Low Dose		Week 4	150.0	128.0	22.0
Xanomeline Low Dose		Week 6	138.0	128.0	10.0
Xanomeline Low Dose		Week 6	140.0	138.0	2.0
Xanomeline Low Dose		Week 6	134.0	128.0	6.0
Xanomeline Low Dose		Week 8	124.0	128.0	-4.0
Xanomeline Low Dose		Week 8	126.0	138.0	-12.0
Xanomeline Low Dose		Week 8	128.0	128.0	0.0
Xanomeline Low Dose			138.0	128.0
Xanomeline Low Dose			150.0	138.0
Xanomeline Low Dose			138.0	128.0
Xanomeline Low Dose			122.0	128.0
Xanomeline Low Dose			132.0	138.0
Xanomeline Low Dose			136.0	128.0
Placebo		Week 12	132.0	130.0	2.0
Placebo		Week 12	110.0	120.0	-10.0
Placebo		Week 12	128.0	120.0	8.0
Placebo		Week 16	130.0	130.0	0.0
Placebo		Week 16	120.0	120.0	0.0
Placebo		Week 16	124.0	120.0	4.0
Placebo		Week 2	128.0	130.0	-2.0
Placebo		Week 2	118.0	120.0	-2.0
Placebo		Week 2	112.0	120.0	-8.0
Placebo		Week 20	140.0	130.0	10.0
Placebo		Week 20	118.0	120.0	-2.0
Placebo		Week 20	124.0	120.0	4.0
Placebo		Week 24	128.0	130.0	-2.0
Placebo		Week 24	122.0	120.0	2.0
Placebo		Week 24	116.0	120.0	-4.0
Placebo		Week 26	124.0	130.0	-6.0
Placebo		Week 26	118.0	120.0	-2.0
Placebo		Week 26	114.0	120.0	-6.0
Placebo		Week 4	134.0	130.0	4.0
Placebo		Week 4	120.0	120.0	0.0
Placebo		Week 4	120.0	120.0	0.0
Placebo		Week 6	120.0	130.0	-10.0
Placebo		Week 6	110.0	120.0	-10.0
Placebo		Week 6	114.0	120.0	-6.0
Placebo		Week 8	138.0	130.0	8.0
Placebo		Week 8	130.0	120.0	10.0
Placebo		Week 8	130.0	120.0	10.0
Placebo			130.0	130.0
Placebo			120.0	120.0
Placebo			124.0	120.0
Placebo			130.0	130.0
Placebo			120.0	120.0
Placebo			116.0	120.0
Xanomeline High Dose		Week 12	130.0	140.0	-10.0
Xanomeline High Dose		Week 12	120.0	130.0	-10.0
Xanomeline High Dose		Week 12	132.0	140.0	-8.0
Xanomeline High Dose		Week 16	142.0	140.0	2.0
Xanomeline High Dose		Week 16	128.0	130.0	-2.0
Xanomeline High Dose		Week 16	120.0	140.0	-20.0
Xanomeline High Dose		Week 2	128.0	140.0	-12.0
Xanomeline High Dose		Week 2	130.0	130.0	0.0
Xanomeline High Dose		Week 2	128.0	140.0	-12.0
Xanomeline High Dose		Week 20	110.0	140.0	-30.0
Xanomeline High Dose		Week 20	118.0	130.0	-12.0
Xanomeline High Dose		Week 20	114.0	140.0	-26.0
Xanomeline High Dose		Week 24	130.0	140.0	-10.0
Xanomeline High Dose		Week 24	140.0	130.0	10.0
Xanomeline High Dose		Week 24	120.0	140.0	-20.0
Xanomeline High Dose		Week 26	108.0	140.0	-32.0
Xanomeline High Dose		Week 26	110.0	130.0	-20.0
Xanomeline High Dose		Week 26	112.0	140.0	-28.0
Xanomeline High Dose		Week 4	138.0	140.0	-2.0
Xanomeline High Dose		Week 4	130.0	130.0	0.0
Xanomeline High Dose		Week 4	132.0	140.0	-8.0
Xanomeline High Dose		Week 6	120.0	140.0	-20.0
Xanomeline High Dose		Week 6	128.0	130.0	-2.0
Xanomeline High Dose		Week 6	120.0	140.0	-20.0
Xanomeline High Dose		Week 8	140.0	140.0	0.0
Xanomeline High Dose		Week 8	144.0	130.0	14.0
Xanomeline High Dose		Week 8	136.0	140.0	-4.0
Xanomeline High Dose			132.0	140.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			132.0	140.0
Xanomeline High Dose			120.0	140.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			128.0	140.0
Xanomeline Low Dose		Week 2	130.0	126.0	4.0
Xanomeline Low Dose		Week 2	124.0	110.0	14.0
Xanomeline Low Dose		Week 2	130.0	118.0	12.0
Xanomeline Low Dose		Week 4	124.0	126.0	-2.0
Xanomeline Low Dose		Week 4	124.0	110.0	14.0
Xanomeline Low Dose		Week 4	132.0	118.0	14.0
Xanomeline Low Dose		Week 6	130.0	126.0	4.0
Xanomeline Low Dose		Week 6	124.0	110.0	14.0
Xanomeline Low Dose		Week 6	138.0	118.0	20.0
Xanomeline Low Dose		Week 8	140.0	126.0	14.0
Xanomeline Low Dose		Week 8	134.0	110.0	24.0
Xanomeline Low Dose		Week 8	130.0	118.0	12.0
Xanomeline Low Dose			150.0	126.0
Xanomeline Low Dose			130.0	110.0
Xanomeline Low Dose			124.0	118.0
Xanomeline Low Dose			128.0	126.0
Xanomeline Low Dose			116.0	110.0
Xanomeline Low Dose			122.0	118.0
Xanomeline High Dose		Week 2	140.0	140.0	0.0
Xanomeline High Dose		Week 2	138.0	140.0	-2.0
Xanomeline High Dose		Week 2	128.0	122.0	6.0
Xanomeline High Dose		Week 4	140.0	140.0	0.0
Xanomeline High Dose		Week 4	150.0	140.0	10.0
Xanomeline High Dose		Week 4	130.0	122.0	8.0
Xanomeline High Dose		Week 6	140.0	140.0	0.0
Xanomeline High Dose		Week 6	118.0	140.0	-22.0
Xanomeline High Dose		Week 6	132.0	122.0	10.0
Xanomeline High Dose			150.0	140.0
Xanomeline High Dose			130.0	140.0
Xanomeline High Dose			130.0	122.0
Xanomeline Low Dose		Week 12	122.0	130.0	-8.0
Xanomeline Low Dose		Week 12	110.0	128.0	-18.0
Xanomeline Low Dose		Week 12	122.0	124.0	-2.0
Xanomeline Low Dose		Week 2	132.0	130.0	2.0
Xanomeline Low Dose		Week 2	130.0	128.0	2.0
Xanomeline Low Dose		Week 2	128.0	124.0	4.0
Xanomeline Low Dose		Week 4	130.0	130.0	0.0
Xanomeline Low Dose		Week 4	132.0	128.0	4.0
Xanomeline Low Dose		Week 4	130.0	124.0	6.0
Xanomeline Low Dose		Week 6	120.0	130.0	-10.0
Xanomeline Low Dose		Week 6	122.0	128.0	-6.0
Xanomeline Low Dose		Week 6	124.0	124.0	0.0
Xanomeline Low Dose		Week 8	140.0	130.0	10.0
Xanomeline Low Dose		Week 8	142.0	128.0	14.0
Xanomeline Low Dose		Week 8	134.0	124.0	10.0
Xanomeline Low Dose			122.0	130.0
Xanomeline Low Dose			150.0	128.0
Xanomeline Low Dose			152.0	124.0
Xanomeline Low Dose			120.0	130.0
Xanomeline Low Dose			120.0	128.0
Xanomeline Low Dose			110.0	124.0
Xanomeline High Dose		Week 2	140.0	138.0	2.0
Xanomeline High Dose		Week 2	136.0	128.0	8.0
Xanomeline High Dose		Week 2	124.0	138.0	-14.0
Xanomeline High Dose		Week 4	130.0	138.0	-8.0
Xanomeline High Dose		Week 4	146.0	128.0	18.0
Xanomeline High Dose		Week 4	140.0	138.0	2.0
Xanomeline High Dose		Week 6	122.0	138.0	-16.0
Xanomeline High Dose		Week 6	122.0	128.0	-6.0
Xanomeline High Dose		Week 6	110.0	138.0	-28.0
Xanomeline High Dose		Week 8	138.0	138.0	0.0
Xanomeline High Dose		Week 8	136.0	128.0	8.0
Xanomeline High Dose		Week 8	132.0	138.0	-6.0
Xanomeline High Dose			142.0	138.0
Xanomeline High Dose			150.0	128.0
Xanomeline High Dose			142.0	138.0
Placebo		Week 12	100.0	100.0	0.0
Placebo		Week 12	80.0	110.0	-30.0
Placebo		Week 12	78.0	108.0	-30.0
Placebo		Week 16	100.0	100.0	0.0
Placebo		Week 16	100.0	110.0	-10.0
Placebo		Week 16	102.0	108.0	-6.0
Placebo		Week 2	110.0	100.0	10.0
Placebo		Week 2	120.0	110.0	10.0
Placebo		Week 2	108.0	108.0	0.0
Placebo		Week 20	100.0	100.0	0.0
Placebo		Week 20	98.0	110.0	-12.0
Placebo		Week 20	100.0	108.0	-8.0
Placebo		Week 4	94.0	100.0	-6.0
Placebo		Week 4	98.0	110.0	-12.0
Placebo		Week 4	102.0	108.0	-6.0
Placebo		Week 6	104.0	100.0	4.0
Placebo		Week 6	102.0	110.0	-8.0
Placebo		Week 6	120.0	108.0	12.0
Placebo		Week 8	124.0	100.0	24.0
Placebo		Week 8	120.0	110.0	10.0
Placebo		Week 8	110.0	108.0	2.0
Placebo			110.0	100.0
Placebo			100.0	110.0
Placebo			98.0	108.0
Placebo			112.0	100.0
Placebo			104.0	110.0
Placebo			116.0	108.0
Xanomeline Low Dose		Week 2	150.0	158.0	-8.0
Xanomeline Low Dose		Week 2	148.0	140.0	8.0
Xanomeline Low Dose		Week 2	152.0	160.0	-8.0
Xanomeline Low Dose		Week 4	160.0	158.0	2.0
Xanomeline Low Dose		Week 4	160.0	140.0	20.0
Xanomeline Low Dose		Week 4	170.0	160.0	10.0
Xanomeline Low Dose		Week 6	160.0	158.0	2.0
Xanomeline Low Dose		Week 6	170.0	140.0	30.0
Xanomeline Low Dose		Week 6	164.0	160.0	4.0
Xanomeline Low Dose		Week 8	130.0	158.0	-28.0
Xanomeline Low Dose		Week 8	140.0	140.0	0.0
Xanomeline Low Dose		Week 8	150.0	160.0	-10.0
Xanomeline Low Dose			160.0	158.0
Xanomeline Low Dose			160.0	140.0
Xanomeline Low Dose			150.0	160.0
Xanomeline Low Dose			160.0	158.0
Xanomeline Low Dose			172.0	140.0
Xanomeline Low Dose			176.0	160.0
Placebo		Week 12	120.0	140.0	-20.0
Placebo		Week 12	120.0	120.0	0.0
Placebo		Week 12	122.0	128.0	-6.0
Placebo		Week 16	140.0	140.0	0.0
Placebo		Week 16	124.0	120.0	4.0
Placebo		Week 16	150.0	128.0	22.0
Placebo		Week 2	128.0	140.0	-12.0
Placebo		Week 2	138.0	120.0	18.0
Placebo		Week 2	138.0	128.0	10.0
Placebo		Week 20	132.0	140.0	-8.0
Placebo		Week 20	124.0	120.0	4.0
Placebo		Week 20	120.0	128.0	-8.0
Placebo		Week 24	130.0	140.0	-10.0
Placebo		Week 24	114.0	120.0	-6.0
Placebo		Week 24	130.0	128.0	2.0
Placebo		Week 26	146.0	140.0	6.0
Placebo		Week 26	136.0	120.0	16.0
Placebo		Week 26	122.0	128.0	-6.0
Placebo		Week 4	130.0	140.0	-10.0
Placebo		Week 4	138.0	120.0	18.0
Placebo		Week 4	132.0	128.0	4.0
Placebo		Week 6	134.0	140.0	-6.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	128.0	128.0	0.0
Placebo		Week 8	130.0	140.0	-10.0
Placebo		Week 8	142.0	120.0	22.0
Placebo		Week 8	140.0	128.0	12.0
Placebo			140.0	140.0
Placebo			120.0	120.0
Placebo			140.0	128.0
Placebo			120.0	140.0
Placebo			118.0	120.0
Placebo			120.0	128.0
Placebo		Week 12	140.0	140.0	0.0
Placebo		Week 12	120.0	130.0	-10.0
Placebo		Week 12	140.0	130.0	10.0
Placebo		Week 16	130.0	140.0	-10.0
Placebo		Week 16	122.0	130.0	-8.0
Placebo		Week 16	120.0	130.0	-10.0
Placebo		Week 2	130.0	140.0	-10.0
Placebo		Week 2	110.0	130.0	-20.0
Placebo		Week 2	112.0	130.0	-18.0
Placebo		Week 4	130.0	140.0	-10.0
Placebo		Week 4	130.0	130.0	0.0
Placebo		Week 4	138.0	130.0	8.0
Placebo		Week 6	120.0	140.0	-20.0
Placebo		Week 6	130.0	130.0	0.0
Placebo		Week 6	130.0	130.0	0.0
Placebo		Week 8	130.0	140.0	-10.0
Placebo		Week 8	140.0	130.0	10.0
Placebo		Week 8	128.0	130.0	-2.0
Placebo			140.0	140.0
Placebo			132.0	130.0
Placebo			124.0	130.0
Placebo			138.0	140.0
Placebo			160.0	130.0
Placebo			150.0	130.0
Xanomeline High Dose		Week 12	130.0	110.0	20.0
Xanomeline High Dose		Week 12	128.0	128.0	0.0
Xanomeline High Dose		Week 12	134.0	110.0	24.0
Xanomeline High Dose		Week 16	120.0	110.0	10.0
Xanomeline High Dose		Week 16	122.0	128.0	-6.0
Xanomeline High Dose		Week 16	118.0	110.0	8.0
Xanomeline High Dose		Week 2	130.0	110.0	20.0
Xanomeline High Dose		Week 2	128.0	128.0	0.0
Xanomeline High Dose		Week 2	134.0	110.0	24.0
Xanomeline High Dose		Week 20	118.0	110.0	8.0
Xanomeline High Dose		Week 20	122.0	128.0	-6.0
Xanomeline High Dose		Week 20	120.0	110.0	10.0
Xanomeline High Dose		Week 24	110.0	110.0	0.0
Xanomeline High Dose		Week 24	108.0	128.0	-20.0
Xanomeline High Dose		Week 24	120.0	110.0	10.0
Xanomeline High Dose		Week 26	110.0	110.0	0.0
Xanomeline High Dose		Week 26	126.0	128.0	-2.0
Xanomeline High Dose		Week 26	124.0	110.0	14.0
Xanomeline High Dose		Week 4	126.0	110.0	16.0
Xanomeline High Dose		Week 4	122.0	128.0	-6.0
Xanomeline High Dose		Week 4	120.0	110.0	10.0
Xanomeline High Dose		Week 6	128.0	110.0	18.0
Xanomeline High Dose		Week 6	124.0	128.0	-4.0
Xanomeline High Dose		Week 6	124.0	110.0	14.0
Xanomeline High Dose		Week 8	110.0	110.0	0.0
Xanomeline High Dose		Week 8	120.0	128.0	-8.0
Xanomeline High Dose		Week 8	122.0	110.0	12.0
Xanomeline High Dose			130.0	110.0
Xanomeline High Dose			132.0	128.0
Xanomeline High Dose			118.0	110.0
Xanomeline High Dose			128.0	110.0
Xanomeline High Dose			120.0	128.0
Xanomeline High Dose			130.0	110.0
Placebo		Week 12	120.0	150.0	-30.0
Placebo		Week 12	114.0	148.0	-34.0
Placebo		Week 12	118.0	130.0	-12.0
Placebo		Week 16	150.0	150.0	0.0
Placebo		Week 16	130.0	148.0	-18.0
Placebo		Week 16	130.0	130.0	0.0
Placebo		Week 2	128.0	150.0	-22.0
Placebo		Week 2	110.0	148.0	-38.0
Placebo		Week 2	108.0	130.0	-22.0
Placebo		Week 20	134.0	150.0	-16.0
Placebo		Week 20	120.0	148.0	-28.0
Placebo		Week 20	130.0	130.0	0.0
Placebo		Week 24	140.0	150.0	-10.0
Placebo		Week 24	132.0	148.0	-16.0
Placebo		Week 24	150.0	130.0	20.0
Placebo		Week 26	120.0	150.0	-30.0
Placebo		Week 26	118.0	148.0	-30.0
Placebo		Week 26	120.0	130.0	-10.0
Placebo		Week 4	126.0	150.0	-24.0
Placebo		Week 4	100.0	148.0	-48.0
Placebo		Week 4	110.0	130.0	-20.0
Placebo		Week 6	140.0	150.0	-10.0
Placebo		Week 6	142.0	148.0	-6.0
Placebo		Week 6	140.0	130.0	10.0
Placebo		Week 8	130.0	150.0	-20.0
Placebo		Week 8	108.0	148.0	-40.0
Placebo		Week 8	120.0	130.0	-10.0
Placebo			150.0	150.0
Placebo			134.0	148.0
Placebo			136.0	130.0
Xanomeline Low Dose		Week 12	160.0	140.0	20.0
Xanomeline Low Dose		Week 12	160.0	160.0	0.0
Xanomeline Low Dose		Week 12	150.0	164.0	-14.0
Xanomeline Low Dose		Week 16	156.0	140.0	16.0
Xanomeline Low Dose		Week 16	160.0	160.0	0.0
Xanomeline Low Dose		Week 16	166.0	164.0	2.0
Xanomeline Low Dose		Week 2	158.0	140.0	18.0
Xanomeline Low Dose		Week 2	174.0	160.0	14.0
Xanomeline Low Dose		Week 2	174.0	164.0	10.0
Xanomeline Low Dose		Week 20	156.0	140.0	16.0
Xanomeline Low Dose		Week 20	160.0	160.0	0.0
Xanomeline Low Dose		Week 20	150.0	164.0	-14.0
Xanomeline Low Dose		Week 24	150.0	140.0	10.0
Xanomeline Low Dose		Week 24	140.0	160.0	-20.0
Xanomeline Low Dose		Week 24	142.0	164.0	-22.0
Xanomeline Low Dose		Week 26	150.0	140.0	10.0
Xanomeline Low Dose		Week 26	150.0	160.0	-10.0
Xanomeline Low Dose		Week 26	150.0	164.0	-14.0
Xanomeline Low Dose		Week 4	154.0	140.0	14.0
Xanomeline Low Dose		Week 4	160.0	160.0	0.0
Xanomeline Low Dose		Week 4	164.0	164.0	0.0
Xanomeline Low Dose		Week 6	166.0	140.0	26.0
Xanomeline Low Dose		Week 6	170.0	160.0	10.0
Xanomeline Low Dose		Week 6	170.0	164.0	6.0
Xanomeline Low Dose		Week 8	156.0	140.0	16.0
Xanomeline Low Dose		Week 8	162.0	160.0	2.0
Xanomeline Low Dose		Week 8	160.0	164.0	-4.0
Xanomeline Low Dose			150.0	140.0
Xanomeline Low Dose			152.0	160.0
Xanomeline Low Dose			158.0	164.0
Xanomeline Low Dose			148.0	140.0
Xanomeline Low Dose			158.0	160.0
Xanomeline Low Dose			158.0	164.0
Placebo		Week 12	132.0	122.0	10.0
Placebo		Week 12	138.0	120.0	18.0
Placebo		Week 12	112.0	138.0	-26.0
Placebo		Week 16	122.0	122.0	0.0
Placebo		Week 16	120.0	120.0	0.0
Placebo		Week 16	118.0	138.0	-20.0
Placebo		Week 2	134.0	122.0	12.0
Placebo		Week 2	138.0	120.0	18.0
Placebo		Week 2	128.0	138.0	-10.0
Placebo		Week 20	150.0	122.0	28.0
Placebo		Week 20	128.0	120.0	8.0
Placebo		Week 20	140.0	138.0	2.0
Placebo		Week 24	110.0	122.0	-12.0
Placebo		Week 24	120.0	120.0	0.0
Placebo		Week 24	128.0	138.0	-10.0
Placebo		Week 26	128.0	122.0	6.0
Placebo		Week 26	120.0	120.0	0.0
Placebo		Week 26	120.0	138.0	-18.0
Placebo		Week 4	126.0	122.0	4.0
Placebo		Week 4	126.0	120.0	6.0
Placebo		Week 4	126.0	138.0	-12.0
Placebo		Week 6	118.0	122.0	-4.0
Placebo		Week 6	122.0	120.0	2.0
Placebo		Week 6	134.0	138.0	-4.0
Placebo		Week 8	130.0	122.0	8.0
Placebo		Week 8	142.0	120.0	22.0
Placebo		Week 8	144.0	138.0	6.0
Placebo			146.0	122.0
Placebo			134.0	120.0
Placebo			144.0	138.0
Placebo			118.0	122.0
Placebo			122.0	120.0
Placebo			120.0	138.0
Xanomeline Low Dose		Week 2	130.0	152.0	-22.0
Xanomeline Low Dose		Week 2	134.0	144.0	-10.0
Xanomeline Low Dose		Week 2	132.0	146.0	-14.0
Xanomeline High Dose		Week 12	110.0	140.0	-30.0
Xanomeline High Dose		Week 12	114.0	146.0	-32.0
Xanomeline High Dose		Week 12	116.0	144.0	-28.0
Xanomeline High Dose		Week 16	124.0	140.0	-16.0
Xanomeline High Dose		Week 16	130.0	146.0	-16.0
Xanomeline High Dose		Week 16	126.0	144.0	-18.0
Xanomeline High Dose		Week 2	130.0	140.0	-10.0
Xanomeline High Dose		Week 2	126.0	146.0	-20.0
Xanomeline High Dose		Week 2	128.0	144.0	-16.0
Xanomeline High Dose		Week 20	120.0	140.0	-20.0
Xanomeline High Dose		Week 20	128.0	146.0	-18.0
Xanomeline High Dose		Week 20	124.0	144.0	-20.0
Xanomeline High Dose		Week 24	130.0	140.0	-10.0
Xanomeline High Dose		Week 24	128.0	146.0	-18.0
Xanomeline High Dose		Week 24	126.0	144.0	-18.0
Xanomeline High Dose		Week 4	130.0	140.0	-10.0
Xanomeline High Dose		Week 4	126.0	146.0	-20.0
Xanomeline High Dose		Week 4	128.0	144.0	-16.0
Xanomeline High Dose		Week 6	120.0	140.0	-20.0
Xanomeline High Dose		Week 6	126.0	146.0	-20.0
Xanomeline High Dose		Week 6	124.0	144.0	-20.0
Xanomeline High Dose		Week 8	124.0	140.0	-16.0
Xanomeline High Dose		Week 8	126.0	146.0	-20.0
Xanomeline High Dose		Week 8	124.0	144.0	-20.0
Xanomeline High Dose			138.0	140.0
Xanomeline High Dose			136.0	146.0
Xanomeline High Dose			132.0	144.0
Xanomeline High Dose			132.0	140.0
Xanomeline High Dose			122.0	146.0
Xanomeline High Dose			128.0	144.0
Xanomeline High Dose		Week 2	130.0	142.0	-12.0
Xanomeline High Dose		Week 2	126.0	136.0	-10.0
Xanomeline High Dose		Week 2	126.0	134.0	-8.0
Xanomeline High Dose		Week 4	130.0	142.0	-12.0
Xanomeline High Dose		Week 4	134.0	136.0	-2.0
Xanomeline High Dose		Week 4	132.0	134.0	-2.0
Xanomeline High Dose			150.0	142.0
Xanomeline High Dose			146.0	136.0
Xanomeline High Dose			146.0	134.0
Xanomeline High Dose			132.0	142.0
Xanomeline High Dose			128.0	136.0
Xanomeline High Dose			130.0	134.0
Placebo		Week 12	120.0	148.0	-28.0
Placebo		Week 12	130.0	134.0	-4.0
Placebo		Week 12	130.0	138.0	-8.0
Placebo		Week 16	112.0	148.0	-36.0
Placebo		Week 16	114.0	134.0	-20.0
Placebo		Week 16	112.0	138.0	-26.0
Placebo		Week 2	130.0	148.0	-18.0
Placebo		Week 2	124.0	134.0	-10.0
Placebo		Week 2	126.0	138.0	-12.0
Placebo		Week 20	120.0	148.0	-28.0
Placebo		Week 20	118.0	134.0	-16.0
Placebo		Week 20	116.0	138.0	-22.0
Placebo		Week 24	140.0	148.0	-8.0
Placebo		Week 24	140.0	134.0	6.0
Placebo		Week 24	136.0	138.0	-2.0
Placebo		Week 26	130.0	148.0	-18.0
Placebo		Week 26	126.0	134.0	-8.0
Placebo		Week 26	128.0	138.0	-10.0
Placebo		Week 4	120.0	148.0	-28.0
Placebo		Week 4	118.0	134.0	-16.0
Placebo		Week 4	120.0	138.0	-18.0
Placebo		Week 6	140.0	148.0	-8.0
Placebo		Week 6	130.0	134.0	-4.0
Placebo		Week 6	134.0	138.0	-4.0
Placebo		Week 8	120.0	148.0	-28.0
Placebo		Week 8	118.0	134.0	-16.0
Placebo		Week 8	120.0	138.0	-18.0
Xanomeline Low Dose		Week 2	150.0	160.0	-10.0
Xanomeline Low Dose		Week 2	156.0	170.0	-14.0
Xanomeline Low Dose		Week 2	154.0	166.0	-12.0
Xanomeline Low Dose		Week 4	140.0	160.0	-20.0
Xanomeline Low Dose		Week 4	134.0	170.0	-36.0
Xanomeline Low Dose		Week 4	136.0	166.0	-30.0
Xanomeline Low Dose		Week 6	154.0	160.0	-6.0
Xanomeline Low Dose		Week 6	156.0	170.0	-14.0
Xanomeline Low Dose		Week 6	155.0	166.0	-11.0
Xanomeline Low Dose		Week 8	158.0	160.0	-2.0
Xanomeline Low Dose		Week 8	160.0	170.0	-10.0
Xanomeline Low Dose		Week 8	158.0	166.0	-8.0
Xanomeline Low Dose			170.0	160.0
Xanomeline Low Dose			166.0	170.0
Xanomeline Low Dose			164.0	166.0
Xanomeline Low Dose			150.0	160.0
Xanomeline Low Dose			146.0	170.0
Xanomeline Low Dose			146.0	166.0
Xanomeline Low Dose		Week 2	148.0	160.0	-12.0
Xanomeline Low Dose		Week 2	144.0	154.0	-10.0
Xanomeline Low Dose		Week 2	146.0	156.0	-10.0
Xanomeline Low Dose		Week 4	140.0	160.0	-20.0
Xanomeline Low Dose		Week 4	138.0	154.0	-16.0
Xanomeline Low Dose		Week 4	140.0	156.0	-16.0
Xanomeline Low Dose		Week 6	146.0	160.0	-14.0
Xanomeline Low Dose		Week 6	148.0	154.0	-6.0
Xanomeline Low Dose		Week 6	146.0	156.0	-10.0
Xanomeline Low Dose			110.0	160.0
Xanomeline Low Dose			118.0	154.0
Xanomeline Low Dose			116.0	156.0
Xanomeline Low Dose			118.0	160.0
Xanomeline Low Dose			115.0	154.0
Xanomeline Low Dose			115.0	156.0
Placebo		Week 12	134.0	110.0	24.0
Placebo		Week 12	132.0	120.0	12.0
Placebo		Week 12	134.0	118.0	16.0
Placebo		Week 16	150.0	110.0	40.0
Placebo		Week 16	156.0	120.0	36.0
Placebo		Week 16	154.0	118.0	36.0
Placebo		Week 2	150.0	110.0	40.0
Placebo		Week 2	150.0	120.0	30.0
Placebo		Week 2	148.0	118.0	30.0
Placebo		Week 20	140.0	110.0	30.0
Placebo		Week 20	138.0	120.0	18.0
Placebo		Week 20	136.0	118.0	18.0
Placebo		Week 24	160.0	110.0	50.0
Placebo		Week 24	158.0	120.0	38.0
Placebo		Week 24	156.0	118.0	38.0
Placebo		Week 26	152.0	110.0	42.0
Placebo		Week 26	144.0	120.0	24.0
Placebo		Week 26	148.0	118.0	30.0
Placebo		Week 4	160.0	110.0	50.0
Placebo		Week 4	154.0	120.0	34.0
Placebo		Week 4	152.0	118.0	34.0
Placebo		Week 6	128.0	110.0	18.0
Placebo		Week 6	125.0	120.0	5.0
Placebo		Week 6	126.0	118.0	8.0
Placebo		Week 8	160.0	110.0	50.0
Placebo		Week 8	158.0	120.0	38.0
Placebo		Week 8	156.0	118.0	38.0
Placebo			150.0	110.0
Placebo			150.0	120.0
Placebo			146.0	118.0
Placebo			140.0	110.0
Placebo			134.0	120.0
Placebo			136.0	118.0
Xanomeline High Dose		Week 12	160.0	150.0	10.0
Xanomeline High Dose		Week 12	158.0	146.0	12.0
Xanomeline High Dose		Week 12	156.0	144.0	12.0
Xanomeline High Dose		Week 16	138.0	150.0	-12.0
Xanomeline High Dose		Week 16	138.0	146.0	-8.0
Xanomeline High Dose		Week 16	136.0	144.0	-8.0
Xanomeline High Dose		Week 2	130.0	150.0	-20.0
Xanomeline High Dose		Week 2	126.0	146.0	-20.0
Xanomeline High Dose		Week 2	128.0	144.0	-16.0
Xanomeline High Dose		Week 4	146.0	150.0	-4.0
Xanomeline High Dose		Week 4	132.0	146.0	-14.0
Xanomeline High Dose		Week 4	134.0	144.0	-10.0
Xanomeline High Dose		Week 6	158.0	150.0	8.0
Xanomeline High Dose		Week 6	160.0	146.0	14.0
Xanomeline High Dose		Week 6	158.0	144.0	14.0
Xanomeline High Dose		Week 8	140.0	150.0	-10.0
Xanomeline High Dose		Week 8	144.0	146.0	-2.0
Xanomeline High Dose		Week 8	140.0	144.0	-4.0
Xanomeline High Dose			130.0	150.0
Xanomeline High Dose			136.0	146.0
Xanomeline High Dose			134.0	144.0
Placebo		Week 12	150.0	134.0	16.0
Placebo		Week 12	144.0	130.0	14.0
Placebo		Week 12	140.0	128.0	12.0
Placebo		Week 16	150.0	134.0	16.0
Placebo		Week 16	140.0	130.0	10.0
Placebo		Week 16	144.0	128.0	16.0
Placebo		Week 2	130.0	134.0	-4.0
Placebo		Week 2	120.0	130.0	-10.0
Placebo		Week 2	122.0	128.0	-6.0
Placebo		Week 20	138.0	134.0	4.0
Placebo		Week 20	120.0	130.0	-10.0
Placebo		Week 20	126.0	128.0	-2.0
Placebo		Week 24	130.0	134.0	-4.0
Placebo		Week 24	120.0	130.0	-10.0
Placebo		Week 24	124.0	128.0	-4.0
Placebo		Week 26	120.0	134.0	-14.0
Placebo		Week 26	118.0	130.0	-12.0
Placebo		Week 26	116.0	128.0	-12.0
Placebo		Week 4	140.0	134.0	6.0
Placebo		Week 4	132.0	130.0	2.0
Placebo		Week 4	134.0	128.0	6.0
Placebo		Week 6	140.0	134.0	6.0
Placebo		Week 6	134.0	130.0	4.0
Placebo		Week 6	136.0	128.0	8.0
Placebo		Week 8	150.0	134.0	16.0
Placebo		Week 8	142.0	130.0	12.0
Placebo		Week 8	144.0	128.0	16.0
Placebo			110.0	134.0
Placebo			116.0	130.0
Placebo			114.0	128.0
Placebo		Week 12	160.0	170.0	-10.0
Placebo		Week 12	160.0	172.0	-12.0
Placebo		Week 12	156.0	170.0	-14.0
Placebo		Week 16	160.0	170.0	-10.0
Placebo		Week 16	164.0	172.0	-8.0
Placebo		Week 16	160.0	170.0	-10.0
Placebo		Week 2	168.0	170.0	-2.0
Placebo		Week 2	165.0	172.0	-7.0
Placebo		Week 2	165.0	170.0	-5.0
Placebo		Week 20	160.0	170.0	-10.0
Placebo		Week 20	156.0	172.0	-16.0
Placebo		Week 20	154.0	170.0	-16.0
Placebo		Week 24	145.0	170.0	-25.0
Placebo		Week 24	140.0	172.0	-32.0
Placebo		Week 24	142.0	170.0	-28.0
Placebo		Week 26	140.0	170.0	-30.0
Placebo		Week 26	136.0	172.0	-36.0
Placebo		Week 26	138.0	170.0	-32.0
Placebo		Week 4	160.0	170.0	-10.0
Placebo		Week 4	160.0	172.0	-12.0
Placebo		Week 4	158.0	170.0	-12.0
Placebo		Week 6	158.0	170.0	-12.0
Placebo		Week 6	154.0	172.0	-18.0
Placebo		Week 6	152.0	170.0	-18.0
Placebo		Week 8	160.0	170.0	-10.0
Placebo		Week 8	150.0	172.0	-22.0
Placebo		Week 8	154.0	170.0	-16.0
Placebo			160.0	170.0
Placebo			156.0	172.0
Placebo			152.0	170.0
Placebo			138.0	170.0
Placebo			144.0	172.0
Placebo			144.0	170.0
Xanomeline High Dose		Week 2	150.0	180.0	-30.0
Xanomeline High Dose		Week 2	152.0	180.0	-28.0
Xanomeline High Dose		Week 2	150.0	178.0	-28.0
Xanomeline High Dose		Week 4	150.0	180.0	-30.0
Xanomeline High Dose		Week 4	152.0	180.0	-28.0
Xanomeline High Dose		Week 4	150.0	178.0	-28.0
Xanomeline High Dose		Week 6	170.0	180.0	-10.0
Xanomeline High Dose		Week 6	162.0	180.0	-18.0
Xanomeline High Dose		Week 6	160.0	178.0	-18.0
Xanomeline High Dose			176.0	180.0
Xanomeline High Dose			168.0	180.0
Xanomeline High Dose			166.0	178.0
Xanomeline High Dose			170.0	180.0
Xanomeline High Dose			170.0	180.0
Xanomeline High Dose			164.0	178.0
Xanomeline High Dose		Week 2	124.0	130.0	-6.0
Xanomeline High Dose		Week 2	118.0	138.0	-20.0
Xanomeline High Dose		Week 2	120.0	134.0	-14.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			130.0	138.0
Xanomeline High Dose			126.0	134.0
Xanomeline Low Dose		Week 2	120.0	120.0	0.0
Xanomeline Low Dose		Week 2	114.0	122.0	-8.0
Xanomeline Low Dose		Week 2	115.0	120.0	-5.0
Xanomeline Low Dose		Week 4	120.0	120.0	0.0
Xanomeline Low Dose		Week 4	116.0	122.0	-6.0
Xanomeline Low Dose		Week 4	118.0	120.0	-2.0
Xanomeline Low Dose		Week 12	140.0	164.0	-24.0
Xanomeline Low Dose		Week 12	130.0	166.0	-36.0
Xanomeline Low Dose		Week 12	126.0	164.0	-38.0
Xanomeline Low Dose		Week 2	150.0	164.0	-14.0
Xanomeline Low Dose		Week 2	140.0	166.0	-26.0
Xanomeline Low Dose		Week 2	144.0	164.0	-20.0
Xanomeline Low Dose		Week 4	150.0	164.0	-14.0
Xanomeline Low Dose		Week 4	140.0	166.0	-26.0
Xanomeline Low Dose		Week 4	142.0	164.0	-22.0
Xanomeline Low Dose		Week 6	140.0	164.0	-24.0
Xanomeline Low Dose		Week 6	140.0	166.0	-26.0
Xanomeline Low Dose		Week 6	136.0	164.0	-28.0
Xanomeline Low Dose		Week 8	170.0	164.0	6.0
Xanomeline Low Dose		Week 8	160.0	166.0	-6.0
Xanomeline Low Dose		Week 8	164.0	164.0	0.0
Xanomeline Low Dose			144.0	164.0
Xanomeline Low Dose			140.0	166.0
Xanomeline Low Dose			142.0	164.0
Xanomeline Low Dose			120.0	164.0
Xanomeline Low Dose			118.0	166.0
Xanomeline Low Dose			120.0	164.0
Placebo		Week 12	134.0	146.0	-12.0
Placebo		Week 12	132.0	144.0	-12.0
Placebo		Week 12	134.0	146.0	-12.0
Placebo		Week 16	130.0	146.0	-16.0
Placebo		Week 16	130.0	144.0	-14.0
Placebo		Week 16	130.0	146.0	-16.0
Placebo		Week 2	136.0	146.0	-10.0
Placebo		Week 2	138.0	144.0	-6.0
Placebo		Week 2	136.0	146.0	-10.0
Placebo		Week 20	130.0	146.0	-16.0
Placebo		Week 20	134.0	144.0	-10.0
Placebo		Week 20	132.0	146.0	-14.0
Placebo		Week 24	150.0	146.0	4.0
Placebo		Week 24	156.0	144.0	12.0
Placebo		Week 24	152.0	146.0	6.0
Placebo		Week 26	140.0	146.0	-6.0
Placebo		Week 26	148.0	144.0	4.0
Placebo		Week 26	146.0	146.0	0.0
Placebo		Week 4	148.0	146.0	2.0
Placebo		Week 4	160.0	144.0	16.0
Placebo		Week 4	158.0	146.0	12.0
Placebo		Week 6	136.0	146.0	-10.0
Placebo		Week 6	140.0	144.0	-4.0
Placebo		Week 6	138.0	146.0	-8.0
Placebo		Week 8	140.0	146.0	-6.0
Placebo		Week 8	140.0	144.0	-4.0
Placebo		Week 8	136.0	146.0	-10.0
Placebo			150.0	146.0
Placebo			148.0	144.0
Placebo			146.0	146.0
Placebo			120.0	146.0
Placebo			132.0	144.0
Placebo			130.0	146.0
Xanomeline High Dose		Week 12	158.0	136.0	22.0
Xanomeline High Dose		Week 12	150.0	130.0	20.0
Xanomeline High Dose		Week 12	148.0	132.0	16.0
Xanomeline High Dose		Week 16	132.0	136.0	-4.0
Xanomeline High Dose		Week 16	130.0	130.0	0.0
Xanomeline High Dose		Week 16	134.0	132.0	2.0
Xanomeline High Dose		Week 2	150.0	136.0	14.0
Xanomeline High Dose		Week 2	142.0	130.0	12.0
Xanomeline High Dose		Week 2	144.0	132.0	12.0
Xanomeline High Dose		Week 20	130.0	136.0	-6.0
Xanomeline High Dose		Week 20	124.0	130.0	-6.0
Xanomeline High Dose		Week 20	126.0	132.0	-6.0
Xanomeline High Dose		Week 24	120.0	136.0	-16.0
Xanomeline High Dose		Week 24	128.0	130.0	-2.0
Xanomeline High Dose		Week 24	124.0	132.0	-8.0
Xanomeline High Dose		Week 26	110.0	136.0	-26.0
Xanomeline High Dose		Week 26	112.0	130.0	-18.0
Xanomeline High Dose		Week 26	110.0	132.0	-22.0
Xanomeline High Dose		Week 4	130.0	136.0	-6.0
Xanomeline High Dose		Week 4	134.0	130.0	4.0
Xanomeline High Dose		Week 4	136.0	132.0	4.0
Xanomeline High Dose		Week 6	130.0	136.0	-6.0
Xanomeline High Dose		Week 6	124.0	130.0	-6.0
Xanomeline High Dose		Week 6	126.0	132.0	-6.0
Xanomeline High Dose		Week 8	120.0	136.0	-16.0
Xanomeline High Dose		Week 8	130.0	130.0	0.0
Xanomeline High Dose		Week 8	128.0	132.0	-4.0
Xanomeline High Dose			140.0	136.0
Xanomeline High Dose			134.0	130.0
Xanomeline High Dose			132.0	132.0
Xanomeline Low Dose		Week 12	130.0	140.0	-10.0
Xanomeline Low Dose		Week 12	128.0	136.0	-8.0
Xanomeline Low Dose		Week 12	130.0	138.0	-8.0
Xanomeline Low Dose		Week 16	120.0	140.0	-20.0
Xanomeline Low Dose		Week 16	122.0	136.0	-14.0
Xanomeline Low Dose		Week 16	120.0	138.0	-18.0
Xanomeline Low Dose		Week 2	130.0	140.0	-10.0
Xanomeline Low Dose		Week 2	130.0	136.0	-6.0
Xanomeline Low Dose		Week 2	128.0	138.0	-10.0
Xanomeline Low Dose		Week 20	110.0	140.0	-30.0
Xanomeline Low Dose		Week 20	122.0	136.0	-14.0
Xanomeline Low Dose		Week 20	120.0	138.0	-18.0
Xanomeline Low Dose		Week 24	132.0	140.0	-8.0
Xanomeline Low Dose		Week 24	126.0	136.0	-10.0
Xanomeline Low Dose		Week 24	124.0	138.0	-14.0
Xanomeline Low Dose		Week 26	120.0	140.0	-20.0
Xanomeline Low Dose		Week 26	114.0	136.0	-22.0
Xanomeline Low Dose		Week 26	116.0	138.0	-22.0
Xanomeline Low Dose		Week 4	118.0	140.0	-22.0
Xanomeline Low Dose		Week 4	116.0	136.0	-20.0
Xanomeline Low Dose		Week 4	118.0	138.0	-20.0
Xanomeline Low Dose		Week 6	126.0	140.0	-14.0
Xanomeline Low Dose		Week 6	128.0	136.0	-8.0
Xanomeline Low Dose		Week 6	126.0	138.0	-12.0
Xanomeline Low Dose		Week 8	130.0	140.0	-10.0
Xanomeline Low Dose		Week 8	128.0	136.0	-8.0
Xanomeline Low Dose		Week 8	130.0	138.0	-8.0
Xanomeline Low Dose			120.0	140.0
Xanomeline Low Dose			120.0	136.0
Xanomeline Low Dose			122.0	138.0
Xanomeline Low Dose			126.0	140.0
Xanomeline Low Dose			130.0	136.0
Xanomeline Low Dose			128.0	138.0
Xanomeline High Dose		Week 12	130.0	150.0	-20.0
Xanomeline High Dose		Week 12	136.0	140.0	-4.0
Xanomeline High Dose		Week 12	134.0	144.0	-10.0
Xanomeline High Dose		Week 16	120.0	150.0	-30.0
Xanomeline High Dose		Week 16	122.0	140.0	-18.0
Xanomeline High Dose		Week 16	120.0	144.0	-24.0
Xanomeline High Dose		Week 2	130.0	150.0	-20.0
Xanomeline High Dose		Week 2	140.0	140.0	0.0
Xanomeline High Dose		Week 2	138.0	144.0	-6.0
Xanomeline High Dose		Week 20	110.0	150.0	-40.0
Xanomeline High Dose		Week 20	110.0	140.0	-30.0
Xanomeline High Dose		Week 20	112.0	144.0	-32.0
Xanomeline High Dose		Week 24	130.0	150.0	-20.0
Xanomeline High Dose		Week 24	144.0	140.0	4.0
Xanomeline High Dose		Week 24	142.0	144.0	-2.0
Xanomeline High Dose		Week 26	110.0	150.0	-40.0
Xanomeline High Dose		Week 26	120.0	140.0	-20.0
Xanomeline High Dose		Week 26	118.0	144.0	-26.0
Xanomeline High Dose		Week 4	126.0	150.0	-24.0
Xanomeline High Dose		Week 4	128.0	140.0	-12.0
Xanomeline High Dose		Week 4	126.0	144.0	-18.0
Xanomeline High Dose		Week 6	140.0	150.0	-10.0
Xanomeline High Dose		Week 6	138.0	140.0	-2.0
Xanomeline High Dose		Week 6	138.0	144.0	-6.0
Xanomeline High Dose		Week 8	140.0	150.0	-10.0
Xanomeline High Dose		Week 8	134.0	140.0	-6.0
Xanomeline High Dose		Week 8	136.0	144.0	-8.0
Xanomeline High Dose			130.0	150.0
Xanomeline High Dose			138.0	140.0
Xanomeline High Dose			134.0	144.0
Xanomeline High Dose			142.0	150.0
Xanomeline High Dose			138.0	140.0
Xanomeline High Dose			136.0	144.0
Placebo		Week 12	122.0	150.0	-28.0
Placebo		Week 12	112.0	144.0	-32.0
Placebo		Week 12	115.0	142.0	-27.0
Placebo		Week 16	136.0	150.0	-14.0
Placebo		Week 16	130.0	144.0	-14.0
Placebo		Week 16	132.0	142.0	-10.0
Placebo		Week 2	120.0	150.0	-30.0
Placebo		Week 2	110.0	144.0	-34.0
Placebo		Week 2	114.0	142.0	-28.0
Placebo		Week 4	130.0	150.0	-20.0
Placebo		Week 4	124.0	144.0	-20.0
Placebo		Week 4	128.0	142.0	-14.0
Placebo		Week 6	120.0	150.0	-30.0
Placebo		Week 6	112.0	144.0	-32.0
Placebo		Week 6	114.0	142.0	-28.0
Placebo		Week 8	130.0	150.0	-20.0
Placebo		Week 8	126.0	144.0	-18.0
Placebo		Week 8	128.0	142.0	-14.0
Placebo			136.0	150.0
Placebo			130.0	144.0
Placebo			134.0	142.0
Placebo			140.0	150.0
Placebo			130.0	144.0
Placebo			132.0	142.0
Xanomeline Low Dose		Week 2	170.0	160.0	10.0
Xanomeline Low Dose		Week 2	160.0	160.0	0.0
Xanomeline Low Dose		Week 2	162.0	158.0	4.0
Placebo		Week 2	160.0	122.0	38.0
Placebo		Week 2	158.0	124.0	34.0
Placebo		Week 2	156.0	122.0	34.0
Placebo		Week 4	150.0	122.0	28.0
Placebo		Week 4	160.0	124.0	36.0
Placebo		Week 4	156.0	122.0	34.0
Placebo		Week 6	170.0	122.0	48.0
Placebo		Week 6	172.0	124.0	48.0
Placebo		Week 6	170.0	122.0	48.0
Placebo			144.0	122.0
Placebo			142.0	124.0
Placebo			142.0	122.0
Placebo			130.0	122.0
Placebo			136.0	124.0
Placebo			134.0	122.0
Xanomeline High Dose		Week 2	134.0	142.0	-8.0
Xanomeline High Dose		Week 2	132.0	152.0	-20.0
Xanomeline High Dose		Week 2	134.0	150.0	-16.0
Xanomeline High Dose		Week 4	120.0	142.0	-22.0
Xanomeline High Dose		Week 4	122.0	152.0	-30.0
Xanomeline High Dose		Week 4	120.0	150.0	-30.0
Xanomeline High Dose		Week 6	138.0	142.0	-4.0
Xanomeline High Dose		Week 6	132.0	152.0	-20.0
Xanomeline High Dose		Week 6	134.0	150.0	-16.0
Xanomeline High Dose		Week 8	134.0	142.0	-8.0
Xanomeline High Dose		Week 8	136.0	152.0	-16.0
Xanomeline High Dose		Week 8	138.0	150.0	-12.0
Xanomeline High Dose			138.0	142.0
Xanomeline High Dose			140.0	152.0
Xanomeline High Dose			136.0	150.0
Xanomeline High Dose			150.0	142.0
Xanomeline High Dose			144.0	152.0
Xanomeline High Dose			148.0	150.0
Xanomeline Low Dose		Week 2	150.0	154.0	-4.0
Xanomeline Low Dose		Week 2	156.0	154.0	2.0
Xanomeline Low Dose		Week 2	154.0	152.0	2.0
Xanomeline Low Dose		Week 4	168.0	154.0	14.0
Xanomeline Low Dose		Week 4	160.0	154.0	6.0
Xanomeline Low Dose		Week 4	162.0	152.0	10.0
Xanomeline Low Dose		Week 6	140.0	154.0	-14.0
Xanomeline Low Dose		Week 6	136.0	154.0	-18.0
Xanomeline Low Dose		Week 6	136.0	152.0	-16.0
Xanomeline Low Dose		Week 8	160.0	154.0	6.0
Xanomeline Low Dose		Week 8	156.0	154.0	2.0
Xanomeline Low Dose		Week 8	156.0	152.0	4.0
Xanomeline Low Dose			150.0	154.0
Xanomeline Low Dose			148.0	154.0
Xanomeline Low Dose			150.0	152.0
Xanomeline Low Dose			160.0	154.0
Xanomeline Low Dose			156.0	154.0
Xanomeline Low Dose			154.0	152.0
Placebo		Week 2	138.0	160.0	-22.0
Placebo		Week 2	142.0	152.0	-10.0
Placebo		Week 2	140.0	150.0	-10.0
Placebo		Week 4	152.0	160.0	-8.0
Placebo		Week 4	146.0	152.0	-6.0
Placebo		Week 4	148.0	150.0	-2.0
Placebo			138.0	160.0
Placebo			138.0	152.0
Placebo			140.0	150.0
Placebo		Week 12	160.0	150.0	10.0
Placebo		Week 12	164.0	150.0	14.0
Placebo		Week 12	162.0	150.0	12.0
Placebo		Week 16	160.0	150.0	10.0
Placebo		Week 16	164.0	150.0	14.0
Placebo		Week 16	160.0	150.0	10.0
Placebo		Week 2	152.0	150.0	2.0
Placebo		Week 2	150.0	150.0	0.0
Placebo		Week 2	150.0	150.0	0.0
Placebo		Week 4	148.0	150.0	-2.0
Placebo		Week 4	142.0	150.0	-8.0
Placebo		Week 4	144.0	150.0	-6.0
Placebo		Week 6	152.0	150.0	2.0
Placebo		Week 6	140.0	150.0	-10.0
Placebo		Week 6	146.0	150.0	-4.0
Placebo		Week 8	156.0	150.0	6.0
Placebo		Week 8	158.0	150.0	8.0
Placebo		Week 8	154.0	150.0	4.0
Placebo			160.0	150.0
Placebo			150.0	150.0
Placebo			148.0	150.0
Placebo			150.0	150.0
Placebo			146.0	150.0
Placebo			148.0	150.0
Xanomeline High Dose		Week 12	100.0	140.0	-40.0
Xanomeline High Dose		Week 12	110.0	138.0	-28.0
Xanomeline High Dose		Week 12	108.0	138.0	-30.0
Xanomeline High Dose		Week 16	134.0	140.0	-6.0
Xanomeline High Dose		Week 16	124.0	138.0	-14.0
Xanomeline High Dose		Week 16	126.0	138.0	-12.0
Xanomeline High Dose		Week 2	130.0	140.0	-10.0
Xanomeline High Dose		Week 2	120.0	138.0	-18.0
Xanomeline High Dose		Week 2	124.0	138.0	-14.0
Xanomeline High Dose		Week 20	130.0	140.0	-10.0
Xanomeline High Dose		Week 20	120.0	138.0	-18.0
Xanomeline High Dose		Week 20	122.0	138.0	-16.0
Xanomeline High Dose		Week 24	140.0	140.0	0.0
Xanomeline High Dose		Week 24	130.0	138.0	-8.0
Xanomeline High Dose		Week 24	132.0	138.0	-6.0
Xanomeline High Dose		Week 26	120.0	140.0	-20.0
Xanomeline High Dose		Week 26	124.0	138.0	-14.0
Xanomeline High Dose		Week 26	122.0	138.0	-16.0
Xanomeline High Dose		Week 4	134.0	140.0	-6.0
Xanomeline High Dose		Week 4	124.0	138.0	-14.0
Xanomeline High Dose		Week 4	126.0	138.0	-12.0
Xanomeline High Dose		Week 6	136.0	140.0	-4.0
Xanomeline High Dose		Week 6	130.0	138.0	-8.0
Xanomeline High Dose		Week 6	132.0	138.0	-6.0
Xanomeline High Dose		Week 8	136.0	140.0	-4.0
Xanomeline High Dose		Week 8	142.0	138.0	4.0
Xanomeline High Dose		Week 8	140.0	138.0	2.0
Xanomeline High Dose			116.0	140.0
Xanomeline High Dose			118.0	138.0
Xanomeline High Dose			116.0	138.0
Xanomeline High Dose			134.0	140.0
Xanomeline High Dose			130.0	138.0
Xanomeline High Dose			132.0	138.0
Xanomeline Low Dose		Week 12	156.0	150.0	6.0
Xanomeline Low Dose		Week 12	152.0	152.0	0.0
Xanomeline Low Dose		Week 12	150.0	150.0	0.0
Xanomeline Low Dose		Week 16	130.0	150.0	-20.0
Xanomeline Low Dose		Week 16	140.0	152.0	-12.0
Xanomeline Low Dose		Week 16	138.0	150.0	-12.0
Xanomeline Low Dose		Week 2	144.0	150.0	-6.0
Xanomeline Low Dose		Week 2	148.0	152.0	-4.0
Xanomeline Low Dose		Week 2	146.0	150.0	-4.0
Xanomeline Low Dose		Week 20	140.0	150.0	-10.0
Xanomeline Low Dose		Week 20	146.0	152.0	-6.0
Xanomeline Low Dose		Week 20	144.0	150.0	-6.0
Xanomeline Low Dose		Week 4	160.0	150.0	10.0
Xanomeline Low Dose		Week 4	160.0	152.0	8.0
Xanomeline Low Dose		Week 4	156.0	150.0	6.0
Xanomeline Low Dose		Week 6	154.0	150.0	4.0
Xanomeline Low Dose		Week 6	154.0	152.0	2.0
Xanomeline Low Dose		Week 6	152.0	150.0	2.0
Xanomeline Low Dose		Week 8	160.0	150.0	10.0
Xanomeline Low Dose		Week 8	170.0	152.0	18.0
Xanomeline Low Dose		Week 8	166.0	150.0	16.0
Xanomeline Low Dose			160.0	150.0
Xanomeline Low Dose			154.0	152.0
Xanomeline Low Dose			156.0	150.0
Xanomeline Low Dose			152.0	150.0
Xanomeline Low Dose			154.0	152.0
Xanomeline Low Dose			152.0	150.0
Placebo		Week 12	130.0	160.0	-30.0
Placebo		Week 12	120.0	154.0	-34.0
Placebo		Week 12	124.0	156.0	-32.0
Placebo		Week 16	124.0	160.0	-36.0
Placebo		Week 16	126.0	154.0	-28.0
Placebo		Week 16	122.0	156.0	-34.0
Placebo		Week 2	130.0	160.0	-30.0
Placebo		Week 2	126.0	154.0	-28.0
Placebo		Week 2	124.0	156.0	-32.0
Placebo		Week 20	150.0	160.0	-10.0
Placebo		Week 20	146.0	154.0	-8.0
Placebo		Week 20	148.0	156.0	-8.0
Placebo		Week 24	150.0	160.0	-10.0
Placebo		Week 24	146.0	154.0	-8.0
Placebo		Week 24	144.0	156.0	-12.0
Placebo		Week 26	126.0	160.0	-34.0
Placebo		Week 26	130.0	154.0	-24.0
Placebo		Week 26	132.0	156.0	-24.0
Placebo		Week 4	120.0	160.0	-40.0
Placebo		Week 4	120.0	154.0	-34.0
Placebo		Week 4	118.0	156.0	-38.0
Placebo		Week 6	130.0	160.0	-30.0
Placebo		Week 6	132.0	154.0	-22.0
Placebo		Week 6	130.0	156.0	-26.0
Placebo		Week 8	150.0	160.0	-10.0
Placebo		Week 8	146.0	154.0	-8.0
Placebo		Week 8	144.0	156.0	-12.0
Placebo			130.0	160.0
Placebo			138.0	154.0
Placebo			136.0	156.0
Placebo			120.0	160.0
Placebo			130.0	154.0
Placebo			126.0	156.0
Xanomeline Low Dose		Week 12	150.0	160.0	-10.0
Xanomeline Low Dose		Week 12	156.0	160.0	-4.0
Xanomeline Low Dose		Week 12	152.0	160.0	-8.0
Xanomeline Low Dose		Week 16	130.0	160.0	-30.0
Xanomeline Low Dose		Week 16	130.0	160.0	-30.0
Xanomeline Low Dose		Week 16	130.0	160.0	-30.0
Xanomeline Low Dose		Week 2	130.0	160.0	-30.0
Xanomeline Low Dose		Week 2	134.0	160.0	-26.0
Xanomeline Low Dose		Week 2	136.0	160.0	-24.0
Xanomeline Low Dose		Week 4	140.0	160.0	-20.0
Xanomeline Low Dose		Week 4	140.0	160.0	-20.0
Xanomeline Low Dose		Week 4	142.0	160.0	-18.0
Xanomeline Low Dose		Week 6	162.0	160.0	2.0
Xanomeline Low Dose		Week 6	160.0	160.0	0.0
Xanomeline Low Dose		Week 6	160.0	160.0	0.0
Xanomeline Low Dose		Week 8	140.0	160.0	-20.0
Xanomeline Low Dose		Week 8	136.0	160.0	-24.0
Xanomeline Low Dose		Week 8	144.0	160.0	-16.0
Xanomeline Low Dose			150.0	160.0
Xanomeline Low Dose			150.0	160.0
Xanomeline Low Dose			148.0	160.0
Xanomeline Low Dose			150.0	160.0
Xanomeline Low Dose			156.0	160.0
Xanomeline Low Dose			154.0	160.0
Xanomeline High Dose		Week 12	146.0	170.0	-24.0
Xanomeline High Dose		Week 12	150.0	166.0	-16.0
Xanomeline High Dose		Week 12	154.0	168.0	-14.0
Xanomeline High Dose		Week 16	150.0	170.0	-20.0
Xanomeline High Dose		Week 16	140.0	166.0	-26.0
Xanomeline High Dose		Week 16	142.0	168.0	-26.0
Xanomeline High Dose		Week 2	118.0	170.0	-52.0
Xanomeline High Dose		Week 2	118.0	166.0	-48.0
Xanomeline High Dose		Week 2	120.0	168.0	-48.0
Xanomeline High Dose		Week 20	154.0	170.0	-16.0
Xanomeline High Dose		Week 20	142.0	166.0	-24.0
Xanomeline High Dose		Week 20	146.0	168.0	-22.0
Xanomeline High Dose		Week 24	142.0	170.0	-28.0
Xanomeline High Dose		Week 24	144.0	166.0	-22.0
Xanomeline High Dose		Week 24	140.0	168.0	-28.0
Xanomeline High Dose		Week 26	122.0	170.0	-48.0
Xanomeline High Dose		Week 26	130.0	166.0	-36.0
Xanomeline High Dose		Week 26	128.0	168.0	-40.0
Xanomeline High Dose		Week 4	120.0	170.0	-50.0
Xanomeline High Dose		Week 4	118.0	166.0	-48.0
Xanomeline High Dose		Week 4	116.0	168.0	-52.0
Xanomeline High Dose		Week 6	140.0	170.0	-30.0
Xanomeline High Dose		Week 6	130.0	166.0	-36.0
Xanomeline High Dose		Week 6	126.0	168.0	-42.0
Xanomeline High Dose		Week 8	142.0	170.0	-28.0
Xanomeline High Dose		Week 8	136.0	166.0	-30.0
Xanomeline High Dose		Week 8	138.0	168.0	-30.0
Xanomeline High Dose			120.0	170.0
Xanomeline High Dose			118.0	166.0
Xanomeline High Dose			116.0	168.0
Xanomeline High Dose			130.0	170.0
Xanomeline High Dose			132.0	166.0
Xanomeline High Dose			130.0	168.0
Xanomeline High Dose		Week 2	152.0	154.0	-2.0
Xanomeline High Dose		Week 2	128.0	126.0	2.0
Xanomeline High Dose		Week 2	136.0	144.0	-8.0
Xanomeline High Dose			144.0	154.0
Xanomeline High Dose			136.0	126.0
Xanomeline High Dose			126.0	144.0
Placebo		Week 12	140.0	150.0	-10.0
Placebo		Week 12	130.0	120.0	10.0
Placebo		Week 12	126.0	126.0	0.0
Placebo		Week 16	140.0	150.0	-10.0
Placebo		Week 16	140.0	120.0	20.0
Placebo		Week 16	128.0	126.0	2.0
Placebo		Week 2	134.0	150.0	-16.0
Placebo		Week 2	114.0	120.0	-6.0
Placebo		Week 2	114.0	126.0	-12.0
Placebo		Week 20	134.0	150.0	-16.0
Placebo		Week 20	118.0	120.0	-2.0
Placebo		Week 20	110.0	126.0	-16.0
Placebo		Week 24	158.0	150.0	8.0
Placebo		Week 24	144.0	120.0	24.0
Placebo		Week 24	130.0	126.0	4.0
Placebo		Week 26	146.0	150.0	-4.0
Placebo		Week 26	118.0	120.0	-2.0
Placebo		Week 26	112.0	126.0	-14.0
Placebo		Week 4	156.0	150.0	6.0
Placebo		Week 4	130.0	120.0	10.0
Placebo		Week 4	128.0	126.0	2.0
Placebo		Week 6	152.0	150.0	2.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	128.0	126.0	2.0
Placebo		Week 8	156.0	150.0	6.0
Placebo		Week 8	124.0	120.0	4.0
Placebo		Week 8	130.0	126.0	4.0
Placebo			120.0	150.0
Placebo			116.0	120.0
Placebo			118.0	126.0
Placebo			130.0	150.0
Placebo			112.0	120.0
Placebo			110.0	126.0
Xanomeline Low Dose		Week 2	160.0	164.0	-4.0
Xanomeline Low Dose		Week 2	158.0	140.0	18.0
Xanomeline Low Dose		Week 2	160.0	150.0	10.0
Xanomeline Low Dose		Week 4	168.0	164.0	4.0
Xanomeline Low Dose		Week 4	150.0	140.0	10.0
Xanomeline Low Dose		Week 4	160.0	150.0	10.0
Xanomeline Low Dose		Week 6	162.0	164.0	-2.0
Xanomeline Low Dose		Week 6	140.0	140.0	0.0
Xanomeline Low Dose		Week 6	160.0	150.0	10.0
Xanomeline Low Dose		Week 8	160.0	164.0	-4.0
Xanomeline Low Dose		Week 8	130.0	140.0	-10.0
Xanomeline Low Dose		Week 8	126.0	150.0	-24.0
Xanomeline Low Dose			164.0	164.0
Xanomeline Low Dose			162.0	140.0
Xanomeline Low Dose			160.0	150.0
Xanomeline Low Dose			140.0	164.0
Xanomeline Low Dose			124.0	140.0
Xanomeline Low Dose			116.0	150.0
Xanomeline Low Dose		Week 12	150.0	130.0	20.0
Xanomeline Low Dose		Week 12	140.0	150.0	-10.0
Xanomeline Low Dose		Week 12	150.0	140.0	10.0
Xanomeline Low Dose		Week 16	130.0	130.0	0.0
Xanomeline Low Dose		Week 16	140.0	150.0	-10.0
Xanomeline Low Dose		Week 16	150.0	140.0	10.0
Xanomeline Low Dose		Week 2	150.0	130.0	20.0
Xanomeline Low Dose		Week 2	140.0	150.0	-10.0
Xanomeline Low Dose		Week 2	160.0	140.0	20.0
Xanomeline Low Dose		Week 20	130.0	130.0	0.0
Xanomeline Low Dose		Week 20	130.0	150.0	-20.0
Xanomeline Low Dose		Week 20	130.0	140.0	-10.0
Xanomeline Low Dose		Week 24	100.0	130.0	-30.0
Xanomeline Low Dose		Week 24	120.0	150.0	-30.0
Xanomeline Low Dose		Week 24	150.0	140.0	10.0
Xanomeline Low Dose		Week 26	130.0	130.0	0.0
Xanomeline Low Dose		Week 26	140.0	150.0	-10.0
Xanomeline Low Dose		Week 26	150.0	140.0	10.0
Xanomeline Low Dose		Week 4	150.0	130.0	20.0
Xanomeline Low Dose		Week 4	160.0	150.0	10.0
Xanomeline Low Dose		Week 4	120.0	140.0	-20.0
Xanomeline Low Dose		Week 6	140.0	130.0	10.0
Xanomeline Low Dose		Week 6	130.0	150.0	-20.0
Xanomeline Low Dose		Week 6	160.0	140.0	20.0
Xanomeline Low Dose		Week 8	130.0	130.0	0.0
Xanomeline Low Dose		Week 8	130.0	150.0	-20.0
Xanomeline Low Dose		Week 8	130.0	140.0	-10.0
Xanomeline Low Dose			140.0	130.0
Xanomeline Low Dose			150.0	150.0
Xanomeline Low Dose			160.0	140.0
Xanomeline Low Dose			150.0	130.0
Xanomeline Low Dose			150.0	150.0
Xanomeline Low Dose			160.0	140.0
Xanomeline Low Dose		Week 12	140.0	140.0	0.0
Xanomeline Low Dose		Week 12	150.0	150.0	0.0
Xanomeline Low Dose		Week 12	150.0	150.0	0.0
Xanomeline Low Dose		Week 16	140.0	140.0	0.0
Xanomeline Low Dose		Week 16	140.0	150.0	-10.0
Xanomeline Low Dose		Week 16	140.0	150.0	-10.0
Xanomeline Low Dose		Week 2	150.0	140.0	10.0
Xanomeline Low Dose		Week 2	140.0	150.0	-10.0
Xanomeline Low Dose		Week 2	150.0	150.0	0.0
Xanomeline Low Dose		Week 20	140.0	140.0	0.0
Xanomeline Low Dose		Week 20	140.0	150.0	-10.0
Xanomeline Low Dose		Week 20	140.0	150.0	-10.0
Xanomeline Low Dose		Week 24	150.0	140.0	10.0
Xanomeline Low Dose		Week 24	150.0	150.0	0.0
Xanomeline Low Dose		Week 24	155.0	150.0	5.0
Xanomeline Low Dose		Week 26	140.0	140.0	0.0
Xanomeline Low Dose		Week 26	150.0	150.0	0.0
Xanomeline Low Dose		Week 26	150.0	150.0	0.0
Xanomeline Low Dose		Week 4	160.0	140.0	20.0
Xanomeline Low Dose		Week 4	160.0	150.0	10.0
Xanomeline Low Dose		Week 4	160.0	150.0	10.0
Xanomeline Low Dose		Week 6	150.0	140.0	10.0
Xanomeline Low Dose		Week 6	150.0	150.0	0.0
Xanomeline Low Dose		Week 6	150.0	150.0	0.0
Xanomeline Low Dose		Week 8	140.0	140.0	0.0
Xanomeline Low Dose		Week 8	140.0	150.0	-10.0
Xanomeline Low Dose		Week 8	150.0	150.0	0.0
Xanomeline Low Dose			130.0	140.0
Xanomeline Low Dose			140.0	150.0
Xanomeline Low Dose			130.0	150.0
Xanomeline High Dose		Week 12	130.0	130.0	0.0
Xanomeline High Dose		Week 12	110.0	130.0	-20.0
Xanomeline High Dose		Week 12	110.0	130.0	-20.0
Xanomeline High Dose		Week 16	130.0	130.0	0.0
Xanomeline High Dose		Week 16	120.0	130.0	-10.0
Xanomeline High Dose		Week 16	130.0	130.0	0.0
Xanomeline High Dose		Week 2	130.0	130.0	0.0
Xanomeline High Dose		Week 2	140.0	130.0	10.0
Xanomeline High Dose		Week 2	140.0	130.0	10.0
Xanomeline High Dose		Week 20	120.0	130.0	-10.0
Xanomeline High Dose		Week 20	110.0	130.0	-20.0
Xanomeline High Dose		Week 20	100.0	130.0	-30.0
Xanomeline High Dose		Week 24	150.0	130.0	20.0
Xanomeline High Dose		Week 24	110.0	130.0	-20.0
Xanomeline High Dose		Week 24	90.0	130.0	-40.0
Xanomeline High Dose		Week 26	110.0	130.0	-20.0
Xanomeline High Dose		Week 26	110.0	130.0	-20.0
Xanomeline High Dose		Week 26	100.0	130.0	-30.0
Xanomeline High Dose		Week 4	150.0	130.0	20.0
Xanomeline High Dose		Week 4	130.0	130.0	0.0
Xanomeline High Dose		Week 4	140.0	130.0	10.0
Xanomeline High Dose		Week 6	130.0	130.0	0.0
Xanomeline High Dose		Week 6	110.0	130.0	-20.0
Xanomeline High Dose		Week 6	110.0	130.0	-20.0
Xanomeline High Dose		Week 8	130.0	130.0	0.0
Xanomeline High Dose		Week 8	140.0	130.0	10.0
Xanomeline High Dose		Week 8	130.0	130.0	0.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			120.0	130.0
Xanomeline High Dose			140.0	130.0
Xanomeline High Dose			140.0	130.0
Xanomeline High Dose			140.0	130.0
Xanomeline High Dose		Week 2	114.0	122.0	-8.0
Xanomeline High Dose		Week 2	106.0	120.0	-14.0
Xanomeline High Dose		Week 2	112.0	120.0	-8.0
Xanomeline High Dose		Week 4	114.0	122.0	-8.0
Xanomeline High Dose		Week 4	100.0	120.0	-20.0
Xanomeline High Dose		Week 4	110.0	120.0	-10.0
Xanomeline High Dose			112.0	122.0
Xanomeline High Dose			104.0	120.0
Xanomeline High Dose			112.0	120.0
Xanomeline High Dose			120.0	122.0
Xanomeline High Dose			110.0	120.0
Xanomeline High Dose			110.0	120.0
Placebo		Week 12	140.0	120.0	20.0
Placebo		Week 12	140.0	110.0	30.0
Placebo		Week 12	130.0	110.0	20.0
Placebo		Week 16	160.0	120.0	40.0
Placebo		Week 16	160.0	110.0	50.0
Placebo		Week 16	160.0	110.0	50.0
Placebo		Week 2	120.0	120.0	0.0
Placebo		Week 2	140.0	110.0	30.0
Placebo		Week 2	130.0	110.0	20.0
Placebo		Week 20	120.0	120.0	0.0
Placebo		Week 20	100.0	110.0	-10.0
Placebo		Week 20	130.0	110.0	20.0
Placebo		Week 24	130.0	120.0	10.0
Placebo		Week 24	120.0	110.0	10.0
Placebo		Week 24	130.0	110.0	20.0
Placebo		Week 26	110.0	120.0	-10.0
Placebo		Week 26	130.0	110.0	20.0
Placebo		Week 26	110.0	110.0	0.0
Placebo		Week 4	130.0	120.0	10.0
Placebo		Week 4	110.0	110.0	0.0
Placebo		Week 4	100.0	110.0	-10.0
Placebo		Week 6	130.0	120.0	10.0
Placebo		Week 6	150.0	110.0	40.0
Placebo		Week 6	130.0	110.0	20.0
Placebo		Week 8	130.0	120.0	10.0
Placebo		Week 8	120.0	110.0	10.0
Placebo		Week 8	140.0	110.0	30.0
Placebo			130.0	120.0
Placebo			130.0	110.0
Placebo			90.0	110.0
Placebo			140.0	120.0
Placebo			150.0	110.0
Placebo			136.0	110.0
Xanomeline High Dose		Week 12	100.0	120.0	-20.0
Xanomeline High Dose		Week 12	110.0	110.0	0.0
Xanomeline High Dose		Week 12	110.0	130.0	-20.0
Xanomeline High Dose		Week 16	150.0	120.0	30.0
Xanomeline High Dose		Week 16	150.0	110.0	40.0
Xanomeline High Dose		Week 16	140.0	130.0	10.0
Xanomeline High Dose		Week 2	120.0	120.0	0.0
Xanomeline High Dose		Week 2	120.0	110.0	10.0
Xanomeline High Dose		Week 2	120.0	130.0	-10.0
Xanomeline High Dose		Week 20	120.0	120.0	0.0
Xanomeline High Dose		Week 20	120.0	110.0	10.0
Xanomeline High Dose		Week 20	124.0	130.0	-6.0
Xanomeline High Dose		Week 24	130.0	120.0	10.0
Xanomeline High Dose		Week 24	140.0	110.0	30.0
Xanomeline High Dose		Week 24	130.0	130.0	0.0
Xanomeline High Dose		Week 26	110.0	120.0	-10.0
Xanomeline High Dose		Week 26	120.0	110.0	10.0
Xanomeline High Dose		Week 26	130.0	130.0	0.0
Xanomeline High Dose		Week 4	150.0	120.0	30.0
Xanomeline High Dose		Week 4	130.0	110.0	20.0
Xanomeline High Dose		Week 4	130.0	130.0	0.0
Xanomeline High Dose		Week 6	120.0	120.0	0.0
Xanomeline High Dose		Week 6	100.0	110.0	-10.0
Xanomeline High Dose		Week 6	90.0	130.0	-40.0
Xanomeline High Dose		Week 8	110.0	120.0	-10.0
Xanomeline High Dose		Week 8	150.0	110.0	40.0
Xanomeline High Dose		Week 8	120.0	130.0	-10.0
Xanomeline High Dose			150.0	120.0
Xanomeline High Dose			120.0	110.0
Xanomeline High Dose			130.0	130.0
Xanomeline High Dose			130.0	120.0
Xanomeline High Dose			140.0	110.0
Xanomeline High Dose			120.0	130.0
Placebo		Week 12	110.0	90.0	20.0
Placebo		Week 12	96.0	90.0	6.0
Placebo		Week 12	90.0	80.0	10.0
Placebo		Week 16	90.0	90.0	0.0
Placebo		Week 16	80.0	90.0	-10.0
Placebo		Week 16	76.0	80.0	-4.0
Placebo		Week 2	110.0	90.0	20.0
Placebo		Week 2	100.0	90.0	10.0
Placebo		Week 2	100.0	80.0	20.0
Placebo		Week 20	90.0	90.0	0.0
Placebo		Week 20	90.0	90.0	0.0
Placebo		Week 20	80.0	80.0	0.0
Placebo		Week 24	100.0	90.0	10.0
Placebo		Week 24	90.0	90.0	0.0
Placebo		Week 24	100.0	80.0	20.0
Placebo		Week 26	100.0	90.0	10.0
Placebo		Week 26	90.0	90.0	0.0
Placebo		Week 26	100.0	80.0	20.0
Placebo		Week 4	100.0	90.0	10.0
Placebo		Week 4	90.0	90.0	0.0
Placebo		Week 4	84.0	80.0	4.0
Placebo		Week 6	100.0	90.0	10.0
Placebo		Week 6	80.0	90.0	-10.0
Placebo		Week 6	84.0	80.0	4.0
Placebo		Week 8	90.0	90.0	0.0
Placebo		Week 8	90.0	90.0	0.0
Placebo		Week 8	90.0	80.0	10.0
Placebo			100.0	90.0
Placebo			90.0	90.0
Placebo			100.0	80.0
Placebo			100.0	90.0
Placebo			100.0	90.0
Placebo			80.0	80.0
Placebo		Week 12	130.0	110.0	20.0
Placebo		Week 12	120.0	110.0	10.0
Placebo		Week 12	120.0	100.0	20.0
Placebo		Week 16	120.0	110.0	10.0
Placebo		Week 16	120.0	110.0	10.0
Placebo		Week 16	120.0	100.0	20.0
Placebo		Week 2	120.0	110.0	10.0
Placebo		Week 2	120.0	110.0	10.0
Placebo		Week 2	120.0	100.0	20.0
Placebo		Week 20	130.0	110.0	20.0
Placebo		Week 20	130.0	110.0	20.0
Placebo		Week 20	128.0	100.0	28.0
Placebo		Week 24	120.0	110.0	10.0
Placebo		Week 24	120.0	110.0	10.0
Placebo		Week 24	120.0	100.0	20.0
Placebo		Week 26	115.0	110.0	5.0
Placebo		Week 26	120.0	110.0	10.0
Placebo		Week 26	120.0	100.0	20.0
Placebo		Week 4	120.0	110.0	10.0
Placebo		Week 4	120.0	110.0	10.0
Placebo		Week 4	120.0	100.0	20.0
Placebo		Week 6	110.0	110.0	0.0
Placebo		Week 6	120.0	110.0	10.0
Placebo		Week 6	120.0	100.0	20.0
Placebo		Week 8	110.0	110.0	0.0
Placebo		Week 8	120.0	110.0	10.0
Placebo		Week 8	120.0	100.0	20.0
Placebo			120.0	110.0
Placebo			120.0	110.0
Placebo			110.0	100.0
Xanomeline Low Dose		Week 12	140.0	120.0	20.0
Xanomeline Low Dose		Week 12	130.0	120.0	10.0
Xanomeline Low Dose		Week 12	130.0	120.0	10.0
Xanomeline Low Dose		Week 2	130.0	120.0	10.0
Xanomeline Low Dose		Week 2	130.0	120.0	10.0
Xanomeline Low Dose		Week 2	130.0	120.0	10.0
Xanomeline Low Dose		Week 4	130.0	120.0	10.0
Xanomeline Low Dose		Week 4	130.0	120.0	10.0
Xanomeline Low Dose		Week 4	130.0	120.0	10.0
Xanomeline Low Dose		Week 6	135.0	120.0	15.0
Xanomeline Low Dose		Week 6	140.0	120.0	20.0
Xanomeline Low Dose		Week 6	140.0	120.0	20.0
Xanomeline Low Dose		Week 8	125.0	120.0	5.0
Xanomeline Low Dose		Week 8	130.0	120.0	10.0
Xanomeline Low Dose		Week 8	120.0	120.0	0.0
Xanomeline Low Dose			130.0	120.0
Xanomeline Low Dose			130.0	120.0
Xanomeline Low Dose			120.0	120.0
Xanomeline Low Dose			135.0	120.0
Xanomeline Low Dose			140.0	120.0
Xanomeline Low Dose			145.0	120.0
Placebo		Week 12	136.0	140.0	-4.0
Placebo		Week 12	144.0	152.0	-8.0
Placebo		Week 12	132.0	150.0	-18.0
Placebo		Week 16	142.0	140.0	2.0
Placebo		Week 16	140.0	152.0	-12.0
Placebo		Week 16	134.0	150.0	-16.0
Placebo		Week 2	160.0	140.0	20.0
Placebo		Week 2	158.0	152.0	6.0
Placebo		Week 2	140.0	150.0	-10.0
Placebo		Week 20	166.0	140.0	26.0
Placebo		Week 20	144.0	152.0	-8.0
Placebo		Week 20	140.0	150.0	-10.0
Placebo		Week 24	168.0	140.0	28.0
Placebo		Week 24	148.0	152.0	-4.0
Placebo		Week 24	140.0	150.0	-10.0
Placebo		Week 26	160.0	140.0	20.0
Placebo		Week 26	154.0	152.0	2.0
Placebo		Week 26	148.0	150.0	-2.0
Placebo		Week 4	160.0	140.0	20.0
Placebo		Week 4	160.0	152.0	8.0
Placebo		Week 4	160.0	150.0	10.0
Placebo		Week 6	142.0	140.0	2.0
Placebo		Week 6	130.0	152.0	-22.0
Placebo		Week 6	140.0	150.0	-10.0
Placebo		Week 8	174.0	140.0	34.0
Placebo		Week 8	146.0	152.0	-6.0
Placebo		Week 8	166.0	150.0	16.0
Placebo			170.0	140.0
Placebo			160.0	152.0
Placebo			158.0	150.0
Placebo			176.0	140.0
Placebo			160.0	152.0
Placebo			156.0	150.0
Xanomeline Low Dose		Week 2	110.0	138.0	-28.0
Xanomeline Low Dose		Week 2	108.0	130.0	-22.0
Xanomeline Low Dose		Week 2	100.0	132.0	-32.0
Xanomeline Low Dose		Week 4	148.0	138.0	10.0
Xanomeline Low Dose		Week 4	142.0	130.0	12.0
Xanomeline Low Dose		Week 4	142.0	132.0	10.0
Xanomeline Low Dose		Week 6	120.0	138.0	-18.0
Xanomeline Low Dose		Week 6	140.0	130.0	10.0
Xanomeline Low Dose		Week 6	142.0	132.0	10.0
Xanomeline Low Dose		Week 8	130.0	138.0	-8.0
Xanomeline Low Dose		Week 8	128.0	130.0	-2.0
Xanomeline Low Dose		Week 8	130.0	132.0	-2.0
Xanomeline Low Dose			110.0	138.0
Xanomeline Low Dose			128.0	130.0
Xanomeline Low Dose			126.0	132.0
Xanomeline Low Dose			140.0	138.0
Xanomeline Low Dose			138.0	130.0
Xanomeline Low Dose			130.0	132.0
Xanomeline Low Dose		Week 12	104.0	114.0	-10.0
Xanomeline Low Dose		Week 12	92.0	112.0	-20.0
Xanomeline Low Dose		Week 12	96.0	104.0	-8.0
Xanomeline Low Dose		Week 16	116.0	114.0	2.0
Xanomeline Low Dose		Week 16	124.0	112.0	12.0
Xanomeline Low Dose		Week 16	126.0	104.0	22.0
Xanomeline Low Dose		Week 2	110.0	114.0	-4.0
Xanomeline Low Dose		Week 2	108.0	112.0	-4.0
Xanomeline Low Dose		Week 2	104.0	104.0	0.0
Xanomeline Low Dose		Week 20	106.0	114.0	-8.0
Xanomeline Low Dose		Week 20	108.0	112.0	-4.0
Xanomeline Low Dose		Week 20	102.0	104.0	-2.0
Xanomeline Low Dose		Week 24	116.0	114.0	2.0
Xanomeline Low Dose		Week 24	92.0	112.0	-20.0
Xanomeline Low Dose		Week 24	104.0	104.0	0.0
Xanomeline Low Dose		Week 26	120.0	114.0	6.0
Xanomeline Low Dose		Week 26	106.0	112.0	-6.0
Xanomeline Low Dose		Week 26	106.0	104.0	2.0
Xanomeline Low Dose		Week 4	102.0	114.0	-12.0
Xanomeline Low Dose		Week 4	96.0	112.0	-16.0
Xanomeline Low Dose		Week 4	102.0	104.0	-2.0
Xanomeline Low Dose		Week 6	106.0	114.0	-8.0
Xanomeline Low Dose		Week 6	100.0	112.0	-12.0
Xanomeline Low Dose		Week 6	98.0	104.0	-6.0
Xanomeline Low Dose		Week 8	102.0	114.0	-12.0
Xanomeline Low Dose		Week 8	98.0	112.0	-14.0
Xanomeline Low Dose		Week 8	100.0	104.0	-4.0
Xanomeline High Dose		Week 12	110.0	158.0	-48.0
Xanomeline High Dose		Week 12	118.0	138.0	-20.0
Xanomeline High Dose		Week 12	116.0	144.0	-28.0
Xanomeline High Dose		Week 16	116.0	158.0	-42.0
Xanomeline High Dose		Week 16	120.0	138.0	-18.0
Xanomeline High Dose		Week 16	124.0	144.0	-20.0
Xanomeline High Dose		Week 2	118.0	158.0	-40.0
Xanomeline High Dose		Week 2	120.0	138.0	-18.0
Xanomeline High Dose		Week 2	120.0	144.0	-24.0
Xanomeline High Dose		Week 20	128.0	158.0	-30.0
Xanomeline High Dose		Week 20	122.0	138.0	-16.0
Xanomeline High Dose		Week 20	130.0	144.0	-14.0
Xanomeline High Dose		Week 24	122.0	158.0	-36.0
Xanomeline High Dose		Week 24	122.0	138.0	-16.0
Xanomeline High Dose		Week 24	124.0	144.0	-20.0
Xanomeline High Dose		Week 26	104.0	158.0	-54.0
Xanomeline High Dose		Week 26	102.0	138.0	-36.0
Xanomeline High Dose		Week 26	114.0	144.0	-30.0
Xanomeline High Dose		Week 4	132.0	158.0	-26.0
Xanomeline High Dose		Week 4	128.0	138.0	-10.0
Xanomeline High Dose		Week 4	130.0	144.0	-14.0
Xanomeline High Dose		Week 6	130.0	158.0	-28.0
Xanomeline High Dose		Week 6	134.0	138.0	-4.0
Xanomeline High Dose		Week 6	134.0	144.0	-10.0
Xanomeline High Dose		Week 8	134.0	158.0	-24.0
Xanomeline High Dose		Week 8	134.0	138.0	-4.0
Xanomeline High Dose		Week 8	124.0	144.0	-20.0
Xanomeline High Dose			126.0	158.0
Xanomeline High Dose			130.0	138.0
Xanomeline High Dose			128.0	144.0
Placebo		Week 12	126.0	132.0	-6.0
Placebo		Week 12	124.0	126.0	-2.0
Placebo		Week 12	124.0	124.0	0.0
Placebo		Week 16	114.0	132.0	-18.0
Placebo		Week 16	112.0	126.0	-14.0
Placebo		Week 16	120.0	124.0	-4.0
Placebo		Week 2	126.0	132.0	-6.0
Placebo		Week 2	116.0	126.0	-10.0
Placebo		Week 2	110.0	124.0	-14.0
Placebo		Week 20	136.0	132.0	4.0
Placebo		Week 20	128.0	126.0	2.0
Placebo		Week 20	126.0	124.0	2.0
Placebo		Week 24	108.0	132.0	-24.0
Placebo		Week 24	112.0	126.0	-14.0
Placebo		Week 24	118.0	124.0	-6.0
Placebo		Week 26	144.0	132.0	12.0
Placebo		Week 26	126.0	126.0	0.0
Placebo		Week 26	112.0	124.0	-12.0
Placebo		Week 4	126.0	132.0	-6.0
Placebo		Week 4	118.0	126.0	-8.0
Placebo		Week 4	110.0	124.0	-14.0
Placebo		Week 6	134.0	132.0	2.0
Placebo		Week 6	114.0	126.0	-12.0
Placebo		Week 6	110.0	124.0	-14.0
Placebo		Week 8	134.0	132.0	2.0
Placebo		Week 8	120.0	126.0	-6.0
Placebo		Week 8	128.0	124.0	4.0
Placebo			132.0	132.0
Placebo			130.0	126.0
Placebo			130.0	124.0
Placebo			126.0	132.0
Placebo			120.0	126.0
Placebo			118.0	124.0
Xanomeline Low Dose		Week 12	155.0	138.0	17.0
Xanomeline Low Dose		Week 12	139.0	129.0	10.0
Xanomeline Low Dose		Week 12	128.0	120.0	8.0
Xanomeline Low Dose		Week 16	146.0	138.0	8.0
Xanomeline Low Dose		Week 16	128.0	129.0	-1.0
Xanomeline Low Dose		Week 16	127.0	120.0	7.0
Xanomeline Low Dose		Week 2	137.0	138.0	-1.0
Xanomeline Low Dose		Week 2	112.0	129.0	-17.0
Xanomeline Low Dose		Week 2	117.0	120.0	-3.0
Xanomeline Low Dose		Week 20	139.0	138.0	1.0
Xanomeline Low Dose		Week 20	128.0	129.0	-1.0
Xanomeline Low Dose		Week 20	148.0	120.0	28.0
Xanomeline Low Dose		Week 24	146.0	138.0	8.0
Xanomeline Low Dose		Week 24	128.0	129.0	-1.0
Xanomeline Low Dose		Week 24	140.0	120.0	20.0
Xanomeline Low Dose		Week 26	146.0	138.0	8.0
Xanomeline Low Dose		Week 26	122.0	129.0	-7.0
Xanomeline Low Dose		Week 26	121.0	120.0	1.0
Xanomeline Low Dose		Week 4	146.0	138.0	8.0
Xanomeline Low Dose		Week 4	135.0	129.0	6.0
Xanomeline Low Dose		Week 4	140.0	120.0	20.0
Xanomeline Low Dose		Week 6	139.0	138.0	1.0
Xanomeline Low Dose		Week 6	104.0	129.0	-25.0
Xanomeline Low Dose		Week 6	110.0	120.0	-10.0
Xanomeline Low Dose		Week 8	144.0	138.0	6.0
Xanomeline Low Dose		Week 8	125.0	129.0	-4.0
Xanomeline Low Dose		Week 8	127.0	120.0	7.0
Xanomeline Low Dose			130.0	138.0
Xanomeline Low Dose			123.0	129.0
Xanomeline Low Dose			126.0	120.0
Xanomeline Low Dose			146.0	138.0
Xanomeline Low Dose			129.0	129.0
Xanomeline Low Dose			142.0	120.0
Xanomeline Low Dose		Week 2	137.0	138.0	-1.0
Xanomeline Low Dose		Week 2	152.0	158.0	-6.0
Xanomeline Low Dose		Week 2	156.0	154.0	2.0
Xanomeline Low Dose		Week 4	130.0	138.0	-8.0
Xanomeline Low Dose		Week 4	156.0	158.0	-2.0
Xanomeline Low Dose		Week 4	139.0	154.0	-15.0
Xanomeline Low Dose		Week 6	131.0	138.0	-7.0
Xanomeline Low Dose		Week 6	153.0	158.0	-5.0
Xanomeline Low Dose		Week 6	128.0	154.0	-26.0
Xanomeline Low Dose		Week 8	131.0	138.0	-7.0
Xanomeline Low Dose		Week 8	144.0	158.0	-14.0
Xanomeline Low Dose		Week 8	126.0	154.0	-28.0
Xanomeline Low Dose			131.0	138.0
Xanomeline Low Dose			150.0	158.0
Xanomeline Low Dose			141.0	154.0
Xanomeline Low Dose			146.0	138.0
Xanomeline Low Dose			152.0	158.0
Xanomeline Low Dose			128.0	154.0
Placebo		Week 2	155.0	145.0	10.0
Placebo		Week 2	162.0	160.0	2.0
Placebo		Week 2	160.0	154.0	6.0
Placebo		Week 4	157.0	145.0	12.0
Placebo		Week 4	160.0	160.0	0.0
Placebo		Week 4	160.0	154.0	6.0
Placebo			152.0	145.0
Placebo			155.0	160.0
Placebo			152.0	154.0
Placebo			148.0	145.0
Placebo			158.0	160.0
Placebo			161.0	154.0
Placebo		Week 12	147.0	160.0	-13.0
Placebo		Week 12	147.0	160.0	-13.0
Placebo		Week 12	149.0	160.0	-11.0
Placebo		Week 16	150.0	160.0	-10.0
Placebo		Week 16	148.0	160.0	-12.0
Placebo		Week 16	141.0	160.0	-19.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 2	160.0	160.0	0.0
Placebo		Week 2	153.0	160.0	-7.0
Placebo		Week 20	115.0	160.0	-45.0
Placebo		Week 20	134.0	160.0	-26.0
Placebo		Week 20	139.0	160.0	-21.0
Placebo		Week 24	140.0	160.0	-20.0
Placebo		Week 24	143.0	160.0	-17.0
Placebo		Week 24	145.0	160.0	-15.0
Placebo		Week 4	150.0	160.0	-10.0
Placebo		Week 4	150.0	160.0	-10.0
Placebo		Week 4	153.0	160.0	-7.0
Placebo		Week 6	146.0	160.0	-14.0
Placebo		Week 6	150.0	160.0	-10.0
Placebo		Week 6	146.0	160.0	-14.0
Placebo		Week 8	156.0	160.0	-4.0
Placebo		Week 8	148.0	160.0	-12.0
Placebo		Week 8	152.0	160.0	-8.0
Placebo			150.0	160.0
Placebo			147.0	160.0
Placebo			145.0	160.0
Placebo			146.0	160.0
Placebo			142.0	160.0
Placebo			141.0	160.0
Xanomeline High Dose		Week 2	106.0	107.0	-1.0
Xanomeline High Dose		Week 2	106.0	104.0	2.0
Xanomeline High Dose		Week 2	107.0	110.0	-3.0
Xanomeline High Dose			108.0	107.0
Xanomeline High Dose			115.0	104.0
Xanomeline High Dose			123.0	110.0
Xanomeline High Dose		Week 2	156.0	153.0	3.0
Xanomeline High Dose		Week 2	153.0	155.0	-2.0
Xanomeline High Dose		Week 2	151.0	160.0	-9.0
Xanomeline High Dose		Week 4	160.0	153.0	7.0
Xanomeline High Dose		Week 4	180.0	155.0	25.0
Xanomeline High Dose		Week 4	179.0	160.0	19.0
Xanomeline High Dose		Week 6	162.0	153.0	9.0
Xanomeline High Dose		Week 6	152.0	155.0	-3.0
Xanomeline High Dose		Week 6	150.0	160.0	-10.0
Xanomeline High Dose		Week 8	149.0	153.0	-4.0
Xanomeline High Dose		Week 8	148.0	155.0	-7.0
Xanomeline High Dose		Week 8	146.0	160.0	-14.0
Xanomeline High Dose			155.0	153.0
Xanomeline High Dose			157.0	155.0
Xanomeline High Dose			154.0	160.0
Xanomeline High Dose			154.0	153.0
Xanomeline High Dose			137.0	155.0
Xanomeline High Dose			136.0	160.0
Placebo		Week 12	131.0	154.0	-23.0
Placebo		Week 12	136.0	151.0	-15.0
Placebo		Week 12	133.0	149.0	-16.0
Placebo		Week 16	145.0	154.0	-9.0
Placebo		Week 16	151.0	151.0	0.0
Placebo		Week 16	156.0	149.0	7.0
Placebo		Week 2	139.0	154.0	-15.0
Placebo		Week 2	140.0	151.0	-11.0
Placebo		Week 2	137.0	149.0	-12.0
Placebo		Week 20	137.0	154.0	-17.0
Placebo		Week 20	149.0	151.0	-2.0
Placebo		Week 20	130.0	149.0	-19.0
Placebo		Week 24	145.0	154.0	-9.0
Placebo		Week 24	136.0	151.0	-15.0
Placebo		Week 24	134.0	149.0	-15.0
Placebo		Week 4	146.0	154.0	-8.0
Placebo		Week 4	144.0	151.0	-7.0
Placebo		Week 4	142.0	149.0	-7.0
Placebo		Week 6	139.0	154.0	-15.0
Placebo		Week 6	147.0	151.0	-4.0
Placebo		Week 6	145.0	149.0	-4.0
Placebo		Week 8	158.0	154.0	4.0
Placebo		Week 8	146.0	151.0	-5.0
Placebo		Week 8	152.0	149.0	3.0
Placebo			145.0	154.0
Placebo			143.0	151.0
Placebo			140.0	149.0
Placebo			145.0	154.0
Placebo			149.0	151.0
Placebo			135.0	149.0
Placebo		Week 12	150.0	170.0	-20.0
Placebo		Week 12	150.0	168.0	-18.0
Placebo		Week 12	150.0	170.0	-20.0
Placebo		Week 16	174.0	170.0	4.0
Placebo		Week 16	156.0	168.0	-12.0
Placebo		Week 16	160.0	170.0	-10.0
Placebo		Week 2	162.0	170.0	-8.0
Placebo		Week 2	164.0	168.0	-4.0
Placebo		Week 2	172.0	170.0	2.0
Placebo		Week 20	150.0	170.0	-20.0
Placebo		Week 20	150.0	168.0	-18.0
Placebo		Week 20	150.0	170.0	-20.0
Placebo		Week 24	144.0	170.0	-26.0
Placebo		Week 24	148.0	168.0	-20.0
Placebo		Week 24	146.0	170.0	-24.0
Placebo		Week 26	130.0	170.0	-40.0
Placebo		Week 26	120.0	168.0	-48.0
Placebo		Week 26	124.0	170.0	-46.0
Placebo		Week 4	130.0	170.0	-40.0
Placebo		Week 4	140.0	168.0	-28.0
Placebo		Week 4	140.0	170.0	-30.0
Placebo		Week 6	134.0	170.0	-36.0
Placebo		Week 6	142.0	168.0	-26.0
Placebo		Week 6	136.0	170.0	-34.0
Placebo		Week 8	164.0	170.0	-6.0
Placebo		Week 8	166.0	168.0	-2.0
Placebo		Week 8	152.0	170.0	-18.0
Placebo			152.0	170.0
Placebo			144.0	168.0
Placebo			140.0	170.0
Placebo			138.0	170.0
Placebo			130.0	168.0
Placebo			140.0	170.0
Placebo		Week 12	140.0	180.0	-40.0
Placebo		Week 12	120.0	180.0	-60.0
Placebo		Week 12	150.0	184.0	-34.0
Placebo		Week 16	140.0	180.0	-40.0
Placebo		Week 16	142.0	180.0	-38.0
Placebo		Week 16	140.0	184.0	-44.0
Placebo		Week 2	150.0	180.0	-30.0
Placebo		Week 2	150.0	180.0	-30.0
Placebo		Week 2	148.0	184.0	-36.0
Placebo		Week 20	190.0	180.0	10.0
Placebo		Week 20	190.0	180.0	10.0
Placebo		Week 20	190.0	184.0	6.0
Placebo		Week 24	180.0	180.0	0.0
Placebo		Week 24	190.0	180.0	10.0
Placebo		Week 24	190.0	184.0	6.0
Placebo		Week 26	160.0	180.0	-20.0
Placebo		Week 26	162.0	180.0	-18.0
Placebo		Week 26	162.0	184.0	-22.0
Placebo		Week 4	160.0	180.0	-20.0
Placebo		Week 4	160.0	180.0	-20.0
Placebo		Week 4	160.0	184.0	-24.0
Placebo		Week 6	200.0	180.0	20.0
Placebo		Week 6	200.0	180.0	20.0
Placebo		Week 6	210.0	184.0	26.0
Placebo		Week 8	180.0	180.0	0.0
Placebo		Week 8	184.0	180.0	4.0
Placebo		Week 8	180.0	184.0	-4.0
Placebo			166.0	180.0
Placebo			152.0	180.0
Placebo			178.0	184.0
Placebo			140.0	180.0
Placebo			142.0	180.0
Placebo			140.0	184.0
Placebo		Week 12	164.0	160.0	4.0
Placebo		Week 12	146.0	150.0	-4.0
Placebo		Week 12	140.0	142.0	-2.0
Placebo		Week 16	130.0	160.0	-30.0
Placebo		Week 16	138.0	150.0	-12.0
Placebo		Week 16	134.0	142.0	-8.0
Placebo		Week 2	172.0	160.0	12.0
Placebo		Week 2	130.0	150.0	-20.0
Placebo		Week 2	128.0	142.0	-14.0
Placebo		Week 20	160.0	160.0	0.0
Placebo		Week 20	160.0	150.0	10.0
Placebo		Week 20	160.0	142.0	18.0
Placebo		Week 24	174.0	160.0	14.0
Placebo		Week 24	176.0	150.0	26.0
Placebo		Week 24	160.0	142.0	18.0
Placebo		Week 26	164.0	160.0	4.0
Placebo		Week 26	164.0	150.0	14.0
Placebo		Week 26	164.0	142.0	22.0
Placebo		Week 4	150.0	160.0	-10.0
Placebo		Week 4	120.0	150.0	-30.0
Placebo		Week 4	130.0	142.0	-12.0
Placebo		Week 6	172.0	160.0	12.0
Placebo		Week 6	160.0	150.0	10.0
Placebo		Week 6	146.0	142.0	4.0
Placebo		Week 8	160.0	160.0	0.0
Placebo		Week 8	168.0	150.0	18.0
Placebo		Week 8	170.0	142.0	28.0
Placebo			162.0	160.0
Placebo			130.0	150.0
Placebo			136.0	142.0
Placebo			162.0	160.0
Placebo			158.0	150.0
Placebo			150.0	142.0
Xanomeline Low Dose		Week 12	138.0	170.0	-32.0
Xanomeline Low Dose		Week 12	142.0	170.0	-28.0
Xanomeline Low Dose		Week 12	148.0	176.0	-28.0
Xanomeline Low Dose		Week 2	158.0	170.0	-12.0
Xanomeline Low Dose		Week 2	152.0	170.0	-18.0
Xanomeline Low Dose		Week 2	186.0	176.0	10.0
Xanomeline Low Dose		Week 4	140.0	170.0	-30.0
Xanomeline Low Dose		Week 4	150.0	170.0	-20.0
Xanomeline Low Dose		Week 4	154.0	176.0	-22.0
Xanomeline Low Dose		Week 6	140.0	170.0	-30.0
Xanomeline Low Dose		Week 6	142.0	170.0	-28.0
Xanomeline Low Dose		Week 6	146.0	176.0	-30.0
Xanomeline Low Dose		Week 8	162.0	170.0	-8.0
Xanomeline Low Dose		Week 8	158.0	170.0	-12.0
Xanomeline Low Dose		Week 8	180.0	176.0	4.0
Xanomeline Low Dose			180.0	170.0
Xanomeline Low Dose			170.0	170.0
Xanomeline Low Dose			176.0	176.0
Xanomeline Low Dose			154.0	170.0
Xanomeline Low Dose			168.0	170.0
Xanomeline Low Dose			150.0	176.0
Xanomeline High Dose		Week 2	122.0	142.0	-20.0
Xanomeline High Dose		Week 2	96.0	138.0	-42.0
Xanomeline High Dose		Week 2	108.0	142.0	-34.0
Xanomeline High Dose		Week 4	120.0	142.0	-22.0
Xanomeline High Dose		Week 4	98.0	138.0	-40.0
Xanomeline High Dose		Week 4	116.0	142.0	-26.0
Xanomeline High Dose		Week 6	140.0	142.0	-2.0
Xanomeline High Dose		Week 6	124.0	138.0	-14.0
Xanomeline High Dose		Week 6	120.0	142.0	-22.0
Xanomeline High Dose		Week 8	164.0	142.0	22.0
Xanomeline High Dose		Week 8	142.0	138.0	4.0
Xanomeline High Dose		Week 8	144.0	142.0	2.0
Xanomeline High Dose			122.0	142.0
Xanomeline High Dose			110.0	138.0
Xanomeline High Dose			112.0	142.0
Xanomeline High Dose			142.0	142.0
Xanomeline High Dose			114.0	138.0
Xanomeline High Dose			140.0	142.0
Xanomeline Low Dose		Week 2	122.0	148.0	-26.0
Xanomeline Low Dose		Week 2	120.0	134.0	-14.0
Xanomeline Low Dose		Week 2	124.0	146.0	-22.0
Xanomeline Low Dose		Week 4	110.0	148.0	-38.0
Xanomeline Low Dose		Week 4	108.0	134.0	-26.0
Xanomeline Low Dose		Week 4	112.0	146.0	-34.0
Xanomeline Low Dose			132.0	148.0
Xanomeline Low Dose			130.0	134.0
Xanomeline Low Dose			128.0	146.0
Xanomeline Low Dose			134.0	148.0
Xanomeline Low Dose			106.0	134.0
Xanomeline Low Dose			130.0	146.0
Xanomeline Low Dose		Week 12	140.0	138.0	2.0
Xanomeline Low Dose		Week 12	150.0	138.0	12.0
Xanomeline Low Dose		Week 12	140.0	134.0	6.0
Xanomeline Low Dose		Week 16	138.0	138.0	0.0
Xanomeline Low Dose		Week 16	124.0	138.0	-14.0
Xanomeline Low Dose		Week 16	144.0	134.0	10.0
Xanomeline Low Dose		Week 2	130.0	138.0	-8.0
Xanomeline Low Dose		Week 2	134.0	138.0	-4.0
Xanomeline Low Dose		Week 2	132.0	134.0	-2.0
Xanomeline Low Dose		Week 20	114.0	138.0	-24.0
Xanomeline Low Dose		Week 20	118.0	138.0	-20.0
Xanomeline Low Dose		Week 20	128.0	134.0	-6.0
Xanomeline Low Dose		Week 24	130.0	138.0	-8.0
Xanomeline Low Dose		Week 24	128.0	138.0	-10.0
Xanomeline Low Dose		Week 24	124.0	134.0	-10.0
Xanomeline Low Dose		Week 26	132.0	138.0	-6.0
Xanomeline Low Dose		Week 26	120.0	138.0	-18.0
Xanomeline Low Dose		Week 26	110.0	134.0	-24.0
Xanomeline Low Dose		Week 4	130.0	138.0	-8.0
Xanomeline Low Dose		Week 4	134.0	138.0	-4.0
Xanomeline Low Dose		Week 4	132.0	134.0	-2.0
Xanomeline Low Dose		Week 6	138.0	138.0	0.0
Xanomeline Low Dose		Week 6	140.0	138.0	2.0
Xanomeline Low Dose		Week 6	138.0	134.0	4.0
Xanomeline Low Dose		Week 8	130.0	138.0	-8.0
Xanomeline Low Dose		Week 8	132.0	138.0	-6.0
Xanomeline Low Dose		Week 8	132.0	134.0	-2.0
Xanomeline Low Dose			120.0	138.0
Xanomeline Low Dose			130.0	138.0
Xanomeline Low Dose			130.0	134.0
Xanomeline Low Dose			124.0	138.0
Xanomeline Low Dose			142.0	138.0
Xanomeline Low Dose			150.0	134.0
Placebo		Week 12	160.0	148.0	12.0
Placebo		Week 12	158.0	152.0	6.0
Placebo		Week 12	158.0	142.0	16.0
Placebo		Week 16	180.0	148.0	32.0
Placebo		Week 16	170.0	152.0	18.0
Placebo		Week 16	160.0	142.0	18.0
Placebo		Week 2	138.0	148.0	-10.0
Placebo		Week 2	166.0	152.0	14.0
Placebo		Week 2	168.0	142.0	26.0
Placebo		Week 20	184.0	148.0	36.0
Placebo		Week 20	196.0	152.0	44.0
Placebo		Week 20	200.0	142.0	58.0
Placebo		Week 24	146.0	148.0	-2.0
Placebo		Week 24	122.0	152.0	-30.0
Placebo		Week 24	130.0	142.0	-12.0
Placebo		Week 26	150.0	148.0	2.0
Placebo		Week 26	132.0	152.0	-20.0
Placebo		Week 26	140.0	142.0	-2.0
Placebo		Week 4	150.0	148.0	2.0
Placebo		Week 4	140.0	152.0	-12.0
Placebo		Week 4	150.0	142.0	8.0
Placebo		Week 6	148.0	148.0	0.0
Placebo		Week 6	154.0	152.0	2.0
Placebo		Week 6	154.0	142.0	12.0
Placebo		Week 8	150.0	148.0	2.0
Placebo		Week 8	140.0	152.0	-12.0
Placebo		Week 8	142.0	142.0	0.0
Placebo			180.0	148.0
Placebo			158.0	152.0
Placebo			176.0	142.0
Placebo			170.0	148.0
Placebo			160.0	152.0
Placebo			170.0	142.0
Xanomeline Low Dose		Week 12	120.0	136.0	-16.0
Xanomeline Low Dose		Week 12	124.0	122.0	2.0
Xanomeline Low Dose		Week 12	122.0	104.0	18.0
Xanomeline Low Dose		Week 2	140.0	136.0	4.0
Xanomeline Low Dose		Week 2	114.0	122.0	-8.0
Xanomeline Low Dose		Week 2	114.0	104.0	10.0
Xanomeline Low Dose		Week 4	120.0	136.0	-16.0
Xanomeline Low Dose		Week 4	122.0	122.0	0.0
Xanomeline Low Dose		Week 4	120.0	104.0	16.0
Xanomeline Low Dose		Week 6	120.0	136.0	-16.0
Xanomeline Low Dose		Week 6	128.0	122.0	6.0
Xanomeline Low Dose		Week 6	124.0	104.0	20.0
Xanomeline Low Dose		Week 8	132.0	136.0	-4.0
Xanomeline Low Dose		Week 8	134.0	122.0	12.0
Xanomeline Low Dose		Week 8	134.0	104.0	30.0
Xanomeline Low Dose			120.0	136.0
Xanomeline Low Dose			122.0	122.0
Xanomeline Low Dose			124.0	104.0
Xanomeline Low Dose			112.0	136.0
Xanomeline Low Dose			110.0	122.0
Xanomeline Low Dose			112.0	104.0
Xanomeline Low Dose		Week 12	110.0	134.0	-24.0
Xanomeline Low Dose		Week 12	112.0	130.0	-18.0
Xanomeline Low Dose		Week 12	110.0	132.0	-22.0
Xanomeline Low Dose		Week 16	142.0	134.0	8.0
Xanomeline Low Dose		Week 16	120.0	130.0	-10.0
Xanomeline Low Dose		Week 16	128.0	132.0	-4.0
Xanomeline Low Dose		Week 2	140.0	134.0	6.0
Xanomeline Low Dose		Week 2	140.0	130.0	10.0
Xanomeline Low Dose		Week 2	142.0	132.0	10.0
Xanomeline Low Dose		Week 20	120.0	134.0	-14.0
Xanomeline Low Dose		Week 20	124.0	130.0	-6.0
Xanomeline Low Dose		Week 20	120.0	132.0	-12.0
Xanomeline Low Dose		Week 24	128.0	134.0	-6.0
Xanomeline Low Dose		Week 24	114.0	130.0	-16.0
Xanomeline Low Dose		Week 24	110.0	132.0	-22.0
Xanomeline Low Dose		Week 4	112.0	134.0	-22.0
Xanomeline Low Dose		Week 4	110.0	130.0	-20.0
Xanomeline Low Dose		Week 4	108.0	132.0	-24.0
Xanomeline Low Dose		Week 6	132.0	134.0	-2.0
Xanomeline Low Dose		Week 6	130.0	130.0	0.0
Xanomeline Low Dose		Week 6	130.0	132.0	-2.0
Xanomeline Low Dose		Week 8	142.0	134.0	8.0
Xanomeline Low Dose		Week 8	132.0	130.0	2.0
Xanomeline Low Dose		Week 8	136.0	132.0	4.0
Xanomeline Low Dose			130.0	134.0
Xanomeline Low Dose			128.0	130.0
Xanomeline Low Dose			126.0	132.0
Xanomeline Low Dose			122.0	134.0
Xanomeline Low Dose			118.0	130.0
Xanomeline Low Dose			124.0	132.0
Placebo		Week 12	130.0	140.0	-10.0
Placebo		Week 12	132.0	132.0	0.0
Placebo		Week 12	130.0	136.0	-6.0
Placebo		Week 16	116.0	140.0	-24.0
Placebo		Week 16	106.0	132.0	-26.0
Placebo		Week 16	110.0	136.0	-26.0
Placebo		Week 2	114.0	140.0	-26.0
Placebo		Week 2	118.0	132.0	-14.0
Placebo		Week 2	118.0	136.0	-18.0
Placebo		Week 20	128.0	140.0	-12.0
Placebo		Week 20	120.0	132.0	-12.0
Placebo		Week 20	122.0	136.0	-14.0
Placebo		Week 24	130.0	140.0	-10.0
Placebo		Week 24	120.0	132.0	-12.0
Placebo		Week 24	130.0	136.0	-6.0
Placebo		Week 26	132.0	140.0	-8.0
Placebo		Week 26	124.0	132.0	-8.0
Placebo		Week 26	130.0	136.0	-6.0
Placebo		Week 4	128.0	140.0	-12.0
Placebo		Week 4	130.0	132.0	-2.0
Placebo		Week 4	130.0	136.0	-6.0
Placebo		Week 6	120.0	140.0	-20.0
Placebo		Week 6	110.0	132.0	-22.0
Placebo		Week 6	120.0	136.0	-16.0
Placebo		Week 8	110.0	140.0	-30.0
Placebo		Week 8	110.0	132.0	-22.0
Placebo		Week 8	118.0	136.0	-18.0
Placebo			130.0	140.0
Placebo			140.0	132.0
Placebo			140.0	136.0
Placebo			116.0	140.0
Placebo			118.0	132.0
Placebo			120.0	136.0
Xanomeline Low Dose		Week 12	124.0	118.0	6.0
Xanomeline Low Dose		Week 12	100.0	112.0	-12.0
Xanomeline Low Dose		Week 12	118.0	112.0	6.0
Xanomeline Low Dose		Week 16	110.0	118.0	-8.0
Xanomeline Low Dose		Week 16	100.0	112.0	-12.0
Xanomeline Low Dose		Week 16	102.0	112.0	-10.0
Xanomeline Low Dose		Week 2	120.0	118.0	2.0
Xanomeline Low Dose		Week 2	112.0	112.0	0.0
Xanomeline Low Dose		Week 2	120.0	112.0	8.0
Xanomeline Low Dose		Week 20	130.0	118.0	12.0
Xanomeline Low Dose		Week 20	110.0	112.0	-2.0
Xanomeline Low Dose		Week 20	120.0	112.0	8.0
Xanomeline Low Dose		Week 24	130.0	118.0	12.0
Xanomeline Low Dose		Week 24	130.0	112.0	18.0
Xanomeline Low Dose		Week 24	120.0	112.0	8.0
Xanomeline Low Dose		Week 4	128.0	118.0	10.0
Xanomeline Low Dose		Week 4	122.0	112.0	10.0
Xanomeline Low Dose		Week 4	122.0	112.0	10.0
Xanomeline Low Dose		Week 6	122.0	118.0	4.0
Xanomeline Low Dose		Week 6	120.0	112.0	8.0
Xanomeline Low Dose		Week 6	120.0	112.0	8.0
Xanomeline Low Dose		Week 8	110.0	118.0	-8.0
Xanomeline Low Dose		Week 8	110.0	112.0	-2.0
Xanomeline Low Dose		Week 8	110.0	112.0	-2.0
Xanomeline Low Dose			128.0	118.0
Xanomeline Low Dose			126.0	112.0
Xanomeline Low Dose			142.0	112.0
Xanomeline Low Dose			122.0	118.0
Xanomeline Low Dose			118.0	112.0
Xanomeline Low Dose			120.0	112.0
Placebo		Week 12	118.0	110.0	8.0
Placebo		Week 12	120.0	122.0	-2.0
Placebo		Week 12	130.0	122.0	8.0
Placebo		Week 16	120.0	110.0	10.0
Placebo		Week 16	118.0	122.0	-4.0
Placebo		Week 16	130.0	122.0	8.0
Placebo		Week 2	130.0	110.0	20.0
Placebo		Week 2	128.0	122.0	6.0
Placebo		Week 2	140.0	122.0	18.0
Placebo		Week 20	110.0	110.0	0.0
Placebo		Week 20	118.0	122.0	-4.0
Placebo		Week 20	128.0	122.0	6.0
Placebo		Week 24	122.0	110.0	12.0
Placebo		Week 24	130.0	122.0	8.0
Placebo		Week 24	130.0	122.0	8.0
Placebo		Week 26	132.0	110.0	22.0
Placebo		Week 26	132.0	122.0	10.0
Placebo		Week 26	132.0	122.0	10.0
Placebo		Week 4	120.0	110.0	10.0
Placebo		Week 4	128.0	122.0	6.0
Placebo		Week 4	132.0	122.0	10.0
Placebo		Week 6	114.0	110.0	4.0
Placebo		Week 6	130.0	122.0	8.0
Placebo		Week 6	150.0	122.0	28.0
Placebo		Week 8	128.0	110.0	18.0
Placebo		Week 8	130.0	122.0	8.0
Placebo		Week 8	130.0	122.0	8.0
Xanomeline High Dose		Week 12	118.0	138.0	-20.0
Xanomeline High Dose		Week 12	120.0	124.0	-4.0
Xanomeline High Dose		Week 12	120.0	118.0	2.0
Xanomeline High Dose		Week 16	126.0	138.0	-12.0
Xanomeline High Dose		Week 16	124.0	124.0	0.0
Xanomeline High Dose		Week 16	116.0	118.0	-2.0
Xanomeline High Dose		Week 2	120.0	138.0	-18.0
Xanomeline High Dose		Week 2	118.0	124.0	-6.0
Xanomeline High Dose		Week 2	118.0	118.0	0.0
Xanomeline High Dose		Week 4	120.0	138.0	-18.0
Xanomeline High Dose		Week 4	124.0	124.0	0.0
Xanomeline High Dose		Week 4	124.0	118.0	6.0
Xanomeline High Dose		Week 6	120.0	138.0	-18.0
Xanomeline High Dose		Week 6	120.0	124.0	-4.0
Xanomeline High Dose		Week 6	124.0	118.0	6.0
Xanomeline High Dose		Week 8	128.0	138.0	-10.0
Xanomeline High Dose		Week 8	130.0	124.0	6.0
Xanomeline High Dose		Week 8	132.0	118.0	14.0
Xanomeline High Dose			118.0	138.0
Xanomeline High Dose			112.0	124.0
Xanomeline High Dose			120.0	118.0
Xanomeline High Dose			118.0	138.0
Xanomeline High Dose			108.0	124.0
Xanomeline High Dose			108.0	118.0
Xanomeline High Dose		Week 2	142.0	142.0	0.0
Xanomeline High Dose		Week 2	140.0	140.0	0.0
Xanomeline High Dose		Week 2	130.0	140.0	-10.0
Xanomeline High Dose		Week 4	154.0	142.0	12.0
Xanomeline High Dose		Week 4	142.0	140.0	2.0
Xanomeline High Dose		Week 4	152.0	140.0	12.0
Xanomeline High Dose			146.0	142.0
Xanomeline High Dose			138.0	140.0
Xanomeline High Dose			130.0	140.0
Xanomeline High Dose			132.0	142.0
Xanomeline High Dose			130.0	140.0
Xanomeline High Dose			128.0	140.0
Xanomeline Low Dose		Week 2	160.0	156.0	4.0
Xanomeline Low Dose		Week 2	162.0	160.0	2.0
Xanomeline Low Dose		Week 2	160.0	162.0	-2.0
Xanomeline Low Dose		Week 4	138.0	156.0	-18.0
Xanomeline Low Dose		Week 4	140.0	160.0	-20.0
Xanomeline Low Dose		Week 4	140.0	162.0	-22.0
Xanomeline Low Dose		Week 6	130.0	156.0	-26.0
Xanomeline Low Dose		Week 6	148.0	160.0	-12.0
Xanomeline Low Dose		Week 6	150.0	162.0	-12.0
Xanomeline Low Dose		Week 8	132.0	156.0	-24.0
Xanomeline Low Dose		Week 8	150.0	160.0	-10.0
Xanomeline Low Dose		Week 8	150.0	162.0	-12.0
Placebo		Week 2	130.0	160.0	-30.0
Placebo		Week 2	148.0	164.0	-16.0
Placebo		Week 2	140.0	164.0	-24.0
Placebo		Week 4	140.0	160.0	-20.0
Placebo		Week 4	132.0	164.0	-32.0
Placebo		Week 4	134.0	164.0	-30.0
Placebo		Week 6	142.0	160.0	-18.0
Placebo		Week 6	130.0	164.0	-34.0
Placebo		Week 6	130.0	164.0	-34.0
Placebo			130.0	160.0
Placebo			134.0	164.0
Placebo			132.0	164.0
Placebo			130.0	160.0
Placebo			120.0	164.0
Placebo			120.0	164.0
Xanomeline Low Dose		Week 12	108.0	120.0	-12.0
Xanomeline Low Dose		Week 12	110.0	120.0	-10.0
Xanomeline Low Dose		Week 12	130.0	120.0	10.0
Xanomeline Low Dose		Week 16	110.0	120.0	-10.0
Xanomeline Low Dose		Week 16	130.0	120.0	10.0
Xanomeline Low Dose		Week 16	120.0	120.0	0.0
Xanomeline Low Dose		Week 2	118.0	120.0	-2.0
Xanomeline Low Dose		Week 2	138.0	120.0	18.0
Xanomeline Low Dose		Week 2	142.0	120.0	22.0
Xanomeline Low Dose		Week 4	124.0	120.0	4.0
Xanomeline Low Dose		Week 4	130.0	120.0	10.0
Xanomeline Low Dose		Week 4	136.0	120.0	16.0
Xanomeline Low Dose		Week 6	120.0	120.0	0.0
Xanomeline Low Dose		Week 6	122.0	120.0	2.0
Xanomeline Low Dose		Week 6	114.0	120.0	-6.0
Xanomeline Low Dose		Week 8	138.0	120.0	18.0
Xanomeline Low Dose		Week 8	140.0	120.0	20.0
Xanomeline Low Dose		Week 8	142.0	120.0	22.0
Xanomeline High Dose		Week 12	138.0	156.0	-18.0
Xanomeline High Dose		Week 12	140.0	192.0	-52.0
Xanomeline High Dose		Week 12	152.0	180.0	-28.0
Xanomeline High Dose		Week 16	138.0	156.0	-18.0
Xanomeline High Dose		Week 16	140.0	192.0	-52.0
Xanomeline High Dose		Week 16	142.0	180.0	-38.0
Xanomeline High Dose		Week 2	140.0	156.0	-16.0
Xanomeline High Dose		Week 2	142.0	192.0	-50.0
Xanomeline High Dose		Week 2	140.0	180.0	-40.0
Xanomeline High Dose		Week 20	120.0	156.0	-36.0
Xanomeline High Dose		Week 20	110.0	192.0	-82.0
Xanomeline High Dose		Week 20	120.0	180.0	-60.0
Xanomeline High Dose		Week 24	160.0	156.0	4.0
Xanomeline High Dose		Week 24	160.0	192.0	-32.0
Xanomeline High Dose		Week 24	150.0	180.0	-30.0
Xanomeline High Dose		Week 26	120.0	156.0	-36.0
Xanomeline High Dose		Week 26	130.0	192.0	-62.0
Xanomeline High Dose		Week 26	132.0	180.0	-48.0
Xanomeline High Dose		Week 4	168.0	156.0	12.0
Xanomeline High Dose		Week 4	142.0	192.0	-50.0
Xanomeline High Dose		Week 4	160.0	180.0	-20.0
Xanomeline High Dose		Week 6	114.0	156.0	-42.0
Xanomeline High Dose		Week 6	120.0	192.0	-72.0
Xanomeline High Dose		Week 6	148.0	180.0	-32.0
Xanomeline High Dose		Week 8	113.0	156.0	-43.0
Xanomeline High Dose		Week 8	160.0	192.0	-32.0
Xanomeline High Dose		Week 8	170.0	180.0	-10.0
Xanomeline High Dose		Week 2	128.0	126.0	2.0
Xanomeline High Dose		Week 2	130.0	124.0	6.0
Xanomeline High Dose		Week 2	132.0	120.0	12.0
Xanomeline High Dose		Week 4	112.0	126.0	-14.0
Xanomeline High Dose		Week 4	108.0	124.0	-16.0
Xanomeline High Dose		Week 4	118.0	120.0	-2.0
Xanomeline High Dose		Week 6	120.0	126.0	-6.0
Xanomeline High Dose		Week 6	120.0	124.0	-4.0
Xanomeline High Dose		Week 6	120.0	120.0	0.0
Xanomeline High Dose		Week 8	130.0	126.0	4.0
Xanomeline High Dose		Week 8	126.0	124.0	2.0
Xanomeline High Dose		Week 8	130.0	120.0	10.0
Xanomeline High Dose			120.0	126.0
Xanomeline High Dose			110.0	124.0
Xanomeline High Dose			112.0	120.0
Xanomeline High Dose			122.0	126.0
Xanomeline High Dose			110.0	124.0
Xanomeline High Dose			108.0	120.0
Xanomeline High Dose		Week 12	142.0	134.0	8.0
Xanomeline High Dose		Week 12	122.0	116.0	6.0
Xanomeline High Dose		Week 12	130.0	122.0	8.0
Xanomeline High Dose		Week 16	140.0	134.0	6.0
Xanomeline High Dose		Week 16	130.0	116.0	14.0
Xanomeline High Dose		Week 16	142.0	122.0	20.0
Xanomeline High Dose		Week 2	150.0	134.0	16.0
Xanomeline High Dose		Week 2	150.0	116.0	34.0
Xanomeline High Dose		Week 2	144.0	122.0	22.0
Xanomeline High Dose		Week 20	134.0	134.0	0.0
Xanomeline High Dose		Week 20	122.0	116.0	6.0
Xanomeline High Dose		Week 20	118.0	122.0	-4.0
Xanomeline High Dose		Week 24	160.0	134.0	26.0
Xanomeline High Dose		Week 24	158.0	116.0	42.0
Xanomeline High Dose		Week 24	152.0	122.0	30.0
Xanomeline High Dose		Week 26	154.0	134.0	20.0
Xanomeline High Dose		Week 26	150.0	116.0	34.0
Xanomeline High Dose		Week 26	150.0	122.0	28.0
Xanomeline High Dose		Week 4	150.0	134.0	16.0
Xanomeline High Dose		Week 4	126.0	116.0	10.0
Xanomeline High Dose		Week 4	130.0	122.0	8.0
Xanomeline High Dose		Week 6	140.0	134.0	6.0
Xanomeline High Dose		Week 6	132.0	116.0	16.0
Xanomeline High Dose		Week 6	136.0	122.0	14.0
Xanomeline High Dose		Week 8	154.0	134.0	20.0
Xanomeline High Dose		Week 8	126.0	116.0	10.0
Xanomeline High Dose		Week 8	130.0	122.0	8.0
Xanomeline High Dose			140.0	134.0
Xanomeline High Dose			142.0	116.0
Xanomeline High Dose			140.0	122.0
Placebo		Week 12	122.0	130.0	-8.0
Placebo		Week 12	112.0	120.0	-8.0
Placebo		Week 12	118.0	132.0	-14.0
Placebo		Week 16	110.0	130.0	-20.0
Placebo		Week 16	112.0	120.0	-8.0
Placebo		Week 16	120.0	132.0	-12.0
Placebo		Week 2	132.0	130.0	2.0
Placebo		Week 2	110.0	120.0	-10.0
Placebo		Week 2	122.0	132.0	-10.0
Placebo		Week 20	124.0	130.0	-6.0
Placebo		Week 20	110.0	120.0	-10.0
Placebo		Week 20	94.0	132.0	-38.0
Placebo		Week 24	134.0	130.0	4.0
Placebo		Week 24	128.0	120.0	8.0
Placebo		Week 24	126.0	132.0	-6.0
Placebo		Week 26	110.0	130.0	-20.0
Placebo		Week 26	100.0	120.0	-20.0
Placebo		Week 26	112.0	132.0	-20.0
Placebo		Week 4	130.0	130.0	0.0
Placebo		Week 4	138.0	120.0	18.0
Placebo		Week 4	134.0	132.0	2.0
Placebo		Week 6	125.0	130.0	-5.0
Placebo		Week 6	124.0	120.0	4.0
Placebo		Week 6	122.0	132.0	-10.0
Placebo		Week 8	130.0	130.0	0.0
Placebo		Week 8	132.0	120.0	12.0
Placebo		Week 8	130.0	132.0	-2.0
Placebo			138.0	130.0
Placebo			112.0	120.0
Placebo			130.0	132.0
Placebo			132.0	130.0
Placebo			140.0	120.0
Placebo			130.0	132.0
Xanomeline High Dose		Week 12	148.0	148.0	0.0
Xanomeline High Dose		Week 12	124.0	138.0	-14.0
Xanomeline High Dose		Week 12	130.0	138.0	-8.0
Xanomeline High Dose		Week 16	160.0	148.0	12.0
Xanomeline High Dose		Week 16	124.0	138.0	-14.0
Xanomeline High Dose		Week 16	138.0	138.0	0.0
Xanomeline High Dose		Week 2	122.0	148.0	-26.0
Xanomeline High Dose		Week 2	112.0	138.0	-26.0
Xanomeline High Dose		Week 2	96.0	138.0	-42.0
Xanomeline High Dose		Week 20	124.0	148.0	-24.0
Xanomeline High Dose		Week 20	118.0	138.0	-20.0
Xanomeline High Dose		Week 20	120.0	138.0	-18.0
Xanomeline High Dose		Week 24	114.0	148.0	-34.0
Xanomeline High Dose		Week 24	104.0	138.0	-34.0
Xanomeline High Dose		Week 24	110.0	138.0	-28.0
Xanomeline High Dose		Week 26	122.0	148.0	-26.0
Xanomeline High Dose		Week 26	112.0	138.0	-26.0
Xanomeline High Dose		Week 26	120.0	138.0	-18.0
Xanomeline High Dose		Week 4	162.0	148.0	14.0
Xanomeline High Dose		Week 4	150.0	138.0	12.0
Xanomeline High Dose		Week 4	150.0	138.0	12.0
Xanomeline High Dose		Week 6	102.0	148.0	-46.0
Xanomeline High Dose		Week 6	102.0	138.0	-36.0
Xanomeline High Dose		Week 6	110.0	138.0	-28.0
Xanomeline High Dose		Week 8	140.0	148.0	-8.0
Xanomeline High Dose		Week 8	142.0	138.0	4.0
Xanomeline High Dose		Week 8	138.0	138.0	0.0
Xanomeline High Dose			118.0	148.0
Xanomeline High Dose			120.0	138.0
Xanomeline High Dose			120.0	138.0
Xanomeline High Dose			132.0	148.0
Xanomeline High Dose			128.0	138.0
Xanomeline High Dose			128.0	138.0
Xanomeline Low Dose		Week 12	142.0	132.0	10.0
Xanomeline Low Dose		Week 12	138.0	122.0	16.0
Xanomeline Low Dose		Week 12	126.0	120.0	6.0
Xanomeline Low Dose		Week 16	138.0	132.0	6.0
Xanomeline Low Dose		Week 16	126.0	122.0	4.0
Xanomeline Low Dose		Week 16	124.0	120.0	4.0
Xanomeline Low Dose		Week 2	130.0	132.0	-2.0
Xanomeline Low Dose		Week 2	128.0	122.0	6.0
Xanomeline Low Dose		Week 2	130.0	120.0	10.0
Xanomeline Low Dose		Week 20	110.0	132.0	-22.0
Xanomeline Low Dose		Week 20	118.0	122.0	-4.0
Xanomeline Low Dose		Week 20	124.0	120.0	4.0
Xanomeline Low Dose		Week 24	128.0	132.0	-4.0
Xanomeline Low Dose		Week 24	126.0	122.0	4.0
Xanomeline Low Dose		Week 24	124.0	120.0	4.0
Xanomeline Low Dose		Week 26	136.0	132.0	4.0
Xanomeline Low Dose		Week 26	132.0	122.0	10.0
Xanomeline Low Dose		Week 26	128.0	120.0	8.0
Xanomeline Low Dose		Week 4	128.0	132.0	-4.0
Xanomeline Low Dose		Week 4	126.0	122.0	4.0
Xanomeline Low Dose		Week 4	124.0	120.0	4.0
Xanomeline Low Dose		Week 6	130.0	132.0	-2.0
Xanomeline Low Dose		Week 6	118.0	122.0	-4.0
Xanomeline Low Dose		Week 6	116.0	120.0	-4.0
Xanomeline Low Dose		Week 8	138.0	132.0	6.0
Xanomeline Low Dose		Week 8	122.0	122.0	0.0
Xanomeline Low Dose		Week 8	120.0	120.0	0.0
Xanomeline Low Dose			136.0	132.0
Xanomeline Low Dose			134.0	122.0
Xanomeline Low Dose			128.0	120.0
Xanomeline Low Dose			128.0	132.0
Xanomeline Low Dose			124.0	122.0
Xanomeline Low Dose			124.0	120.0
Xanomeline High Dose		Week 12	130.0	132.0	-2.0
Xanomeline High Dose		Week 12	132.0	122.0	10.0
Xanomeline High Dose		Week 12	120.0	124.0	-4.0
Xanomeline High Dose		Week 16	128.0	132.0	-4.0
Xanomeline High Dose		Week 16	128.0	122.0	6.0
Xanomeline High Dose		Week 16	118.0	124.0	-6.0
Xanomeline High Dose		Week 2	118.0	132.0	-14.0
Xanomeline High Dose		Week 2	102.0	122.0	-20.0
Xanomeline High Dose		Week 2	106.0	124.0	-18.0
Xanomeline High Dose		Week 20	122.0	132.0	-10.0
Xanomeline High Dose		Week 20	118.0	122.0	-4.0
Xanomeline High Dose		Week 20	120.0	124.0	-4.0
Xanomeline High Dose		Week 24	130.0	132.0	-2.0
Xanomeline High Dose		Week 24	124.0	122.0	2.0
Xanomeline High Dose		Week 24	126.0	124.0	2.0
Xanomeline High Dose		Week 26	122.0	132.0	-10.0
Xanomeline High Dose		Week 26	108.0	122.0	-14.0
Xanomeline High Dose		Week 26	120.0	124.0	-4.0
Xanomeline High Dose		Week 4	118.0	132.0	-14.0
Xanomeline High Dose		Week 4	112.0	122.0	-10.0
Xanomeline High Dose		Week 4	110.0	124.0	-14.0
Xanomeline High Dose		Week 6	102.0	132.0	-30.0
Xanomeline High Dose		Week 6	98.0	122.0	-24.0
Xanomeline High Dose		Week 6	96.0	124.0	-28.0
Xanomeline High Dose		Week 8	120.0	132.0	-12.0
Xanomeline High Dose		Week 8	118.0	122.0	-4.0
Xanomeline High Dose		Week 8	115.0	124.0	-9.0
Xanomeline High Dose			122.0	132.0
Xanomeline High Dose			102.0	122.0
Xanomeline High Dose			112.0	124.0
Xanomeline High Dose			132.0	132.0
Xanomeline High Dose			124.0	122.0
Xanomeline High Dose			122.0	124.0
Xanomeline High Dose		Week 12	120.0	118.0	2.0
Xanomeline High Dose		Week 12	118.0	116.0	2.0
Xanomeline High Dose		Week 12	112.0	116.0	-4.0
Xanomeline High Dose		Week 16	118.0	118.0	0.0
Xanomeline High Dose		Week 16	116.0	116.0	0.0
Xanomeline High Dose		Week 16	116.0	116.0	0.0
Xanomeline High Dose		Week 2	112.0	118.0	-6.0
Xanomeline High Dose		Week 2	110.0	116.0	-6.0
Xanomeline High Dose		Week 2	110.0	116.0	-6.0
Xanomeline High Dose		Week 20	108.0	118.0	-10.0
Xanomeline High Dose		Week 20	98.0	116.0	-18.0
Xanomeline High Dose		Week 20	108.0	116.0	-8.0
Xanomeline High Dose		Week 24	110.0	118.0	-8.0
Xanomeline High Dose		Week 24	102.0	116.0	-14.0
Xanomeline High Dose		Week 24	114.0	116.0	-2.0
Xanomeline High Dose		Week 26	118.0	118.0	0.0
Xanomeline High Dose		Week 26	122.0	116.0	6.0
Xanomeline High Dose		Week 26	108.0	116.0	-8.0
Xanomeline High Dose		Week 4	104.0	118.0	-14.0
Xanomeline High Dose		Week 4	102.0	116.0	-14.0
Xanomeline High Dose		Week 4	108.0	116.0	-8.0
Xanomeline High Dose		Week 6	120.0	118.0	2.0
Xanomeline High Dose		Week 6	118.0	116.0	2.0
Xanomeline High Dose		Week 6	116.0	116.0	0.0
Xanomeline High Dose		Week 8	118.0	118.0	0.0
Xanomeline High Dose		Week 8	122.0	116.0	6.0
Xanomeline High Dose		Week 8	116.0	116.0	0.0
Xanomeline High Dose			112.0	118.0
Xanomeline High Dose			110.0	116.0
Xanomeline High Dose			108.0	116.0
Placebo		Week 2	134.0	132.0	2.0
Placebo		Week 2	130.0	126.0	4.0
Placebo		Week 2	130.0	124.0	6.0
Placebo		Week 4	132.0	132.0	0.0
Placebo		Week 4	122.0	126.0	-4.0
Placebo		Week 4	124.0	124.0	0.0
Placebo		Week 6	132.0	132.0	0.0
Placebo		Week 6	128.0	126.0	2.0
Placebo		Week 6	122.0	124.0	-2.0
Placebo		Week 8	134.0	132.0	2.0
Placebo		Week 8	132.0	126.0	6.0
Placebo		Week 8	138.0	124.0	14.0
Placebo			128.0	132.0
Placebo			124.0	126.0
Placebo			126.0	124.0
Placebo			136.0	132.0
Placebo			132.0	126.0
Placebo			130.0	124.0
Placebo		Week 2	132.0	132.0	0.0
Placebo		Week 2	124.0	128.0	-4.0
Placebo		Week 2	122.0	130.0	-8.0
Placebo		Week 4	132.0	132.0	0.0
Placebo		Week 4	122.0	128.0	-6.0
Placebo		Week 4	126.0	130.0	-4.0
Placebo		Week 6	112.0	132.0	-20.0
Placebo		Week 6	114.0	128.0	-14.0
Placebo		Week 6	110.0	130.0	-20.0
Placebo		Week 8	124.0	132.0	-8.0
Placebo		Week 8	118.0	128.0	-10.0
Placebo		Week 8	116.0	130.0	-14.0
Placebo			162.0	132.0
Placebo			148.0	128.0
Placebo			132.0	130.0
Placebo			132.0	132.0
Placebo			122.0	128.0
Placebo			126.0	130.0
Xanomeline High Dose		Week 12	118.0	110.0	8.0
Xanomeline High Dose		Week 12	110.0	104.0	6.0
Xanomeline High Dose		Week 12	112.0	118.0	-6.0
Xanomeline High Dose		Week 16	110.0	110.0	0.0
Xanomeline High Dose		Week 16	112.0	104.0	8.0
Xanomeline High Dose		Week 16	102.0	118.0	-16.0
Xanomeline High Dose		Week 2	114.0	110.0	4.0
Xanomeline High Dose		Week 2	118.0	104.0	14.0
Xanomeline High Dose		Week 2	120.0	118.0	2.0
Xanomeline High Dose		Week 20	120.0	110.0	10.0
Xanomeline High Dose		Week 20	119.0	104.0	15.0
Xanomeline High Dose		Week 20	122.0	118.0	4.0
Xanomeline High Dose		Week 4	118.0	110.0	8.0
Xanomeline High Dose		Week 4	112.0	104.0	8.0
Xanomeline High Dose		Week 4	114.0	118.0	-4.0
Xanomeline High Dose		Week 6	100.0	110.0	-10.0
Xanomeline High Dose		Week 6	94.0	104.0	-10.0
Xanomeline High Dose		Week 6	98.0	118.0	-20.0
Xanomeline High Dose		Week 8	122.0	110.0	12.0
Xanomeline High Dose		Week 8	118.0	104.0	14.0
Xanomeline High Dose		Week 8	124.0	118.0	6.0
Xanomeline Low Dose		Week 12	146.0	130.0	16.0
Xanomeline Low Dose		Week 12	124.0	112.0	12.0
Xanomeline Low Dose		Week 12	130.0	114.0	16.0
Xanomeline Low Dose		Week 16	132.0	130.0	2.0
Xanomeline Low Dose		Week 16	140.0	112.0	28.0
Xanomeline Low Dose		Week 16	138.0	114.0	24.0
Xanomeline Low Dose		Week 2	148.0	130.0	18.0
Xanomeline Low Dose		Week 2	146.0	112.0	34.0
Xanomeline Low Dose		Week 2	140.0	114.0	26.0
Xanomeline Low Dose		Week 20	122.0	130.0	-8.0
Xanomeline Low Dose		Week 20	118.0	112.0	6.0
Xanomeline Low Dose		Week 20	116.0	114.0	2.0
Xanomeline Low Dose		Week 24	142.0	130.0	12.0
Xanomeline Low Dose		Week 24	160.0	112.0	48.0
Xanomeline Low Dose		Week 24	144.0	114.0	30.0
Xanomeline Low Dose		Week 4	134.0	130.0	4.0
Xanomeline Low Dose		Week 4	124.0	112.0	12.0
Xanomeline Low Dose		Week 4	126.0	114.0	12.0
Xanomeline Low Dose		Week 6	128.0	130.0	-2.0
Xanomeline Low Dose		Week 6	126.0	112.0	14.0
Xanomeline Low Dose		Week 6	124.0	114.0	10.0
Xanomeline Low Dose		Week 8	156.0	130.0	26.0
Xanomeline Low Dose		Week 8	158.0	112.0	46.0
Xanomeline Low Dose		Week 8	156.0	114.0	42.0
Xanomeline Low Dose			134.0	130.0
Xanomeline Low Dose			128.0	112.0
Xanomeline Low Dose			126.0	114.0
Xanomeline Low Dose			132.0	130.0
Xanomeline Low Dose			126.0	112.0
Xanomeline Low Dose			124.0	114.0
Xanomeline Low Dose		Week 2	139.0	145.0	-6.0
Xanomeline Low Dose		Week 2	137.0	146.0	-9.0
Xanomeline Low Dose		Week 2	129.0	153.0	-24.0
Xanomeline Low Dose		Week 4	131.0	145.0	-14.0
Xanomeline Low Dose		Week 4	139.0	146.0	-7.0
Xanomeline Low Dose		Week 4	147.0	153.0	-6.0
Xanomeline Low Dose			154.0	145.0
Xanomeline Low Dose			183.0	146.0
Xanomeline Low Dose			172.0	153.0
Xanomeline Low Dose			130.0	145.0
Xanomeline Low Dose			139.0	146.0
Xanomeline Low Dose			153.0	153.0
Xanomeline High Dose		Week 12	123.0	126.0	-3.0
Xanomeline High Dose		Week 12	138.0	146.0	-8.0
Xanomeline High Dose		Week 12	145.0	139.0	6.0
Xanomeline High Dose		Week 16	125.0	126.0	-1.0
Xanomeline High Dose		Week 16	131.0	146.0	-15.0
Xanomeline High Dose		Week 16	130.0	139.0	-9.0
Xanomeline High Dose		Week 2	131.0	126.0	5.0
Xanomeline High Dose		Week 2	138.0	146.0	-8.0
Xanomeline High Dose		Week 2	146.0	139.0	7.0
Xanomeline High Dose		Week 20	123.0	126.0	-3.0
Xanomeline High Dose		Week 20	115.0	146.0	-31.0
Xanomeline High Dose		Week 20	122.0	139.0	-17.0
Xanomeline High Dose		Week 4	133.0	126.0	7.0
Xanomeline High Dose		Week 4	123.0	146.0	-23.0
Xanomeline High Dose		Week 4	153.0	139.0	14.0
Xanomeline High Dose		Week 6	123.0	126.0	-3.0
Xanomeline High Dose		Week 6	130.0	146.0	-16.0
Xanomeline High Dose		Week 6	122.0	139.0	-17.0
Xanomeline High Dose		Week 8	123.0	126.0	-3.0
Xanomeline High Dose		Week 8	116.0	146.0	-30.0
Xanomeline High Dose		Week 8	132.0	139.0	-7.0
Xanomeline High Dose			124.0	126.0
Xanomeline High Dose			138.0	146.0
Xanomeline High Dose			146.0	139.0
Xanomeline High Dose			123.0	126.0
Xanomeline High Dose			139.0	146.0
Xanomeline High Dose			130.0	139.0
Placebo		Week 12	132.0	132.0	0.0
Placebo		Week 12	122.0	151.0	-29.0
Placebo		Week 12	145.0	154.0	-9.0
Placebo		Week 16	144.0	132.0	12.0
Placebo		Week 16	150.0	151.0	-1.0
Placebo		Week 16	161.0	154.0	7.0
Placebo		Week 2	144.0	132.0	12.0
Placebo		Week 2	152.0	151.0	1.0
Placebo		Week 2	162.0	154.0	8.0
Placebo		Week 20	144.0	132.0	12.0
Placebo		Week 20	146.0	151.0	-5.0
Placebo		Week 20	121.0	154.0	-33.0
Placebo		Week 24	138.0	132.0	6.0
Placebo		Week 24	139.0	151.0	-12.0
Placebo		Week 24	142.0	154.0	-12.0
Placebo		Week 26	145.0	132.0	13.0
Placebo		Week 26	148.0	151.0	-3.0
Placebo		Week 26	145.0	154.0	-9.0
Placebo		Week 4	136.0	132.0	4.0
Placebo		Week 4	137.0	151.0	-14.0
Placebo		Week 4	137.0	154.0	-17.0
Placebo		Week 6	114.0	132.0	-18.0
Placebo		Week 6	150.0	151.0	-1.0
Placebo		Week 6	130.0	154.0	-24.0
Placebo		Week 8	139.0	132.0	7.0
Placebo		Week 8	146.0	151.0	-5.0
Placebo		Week 8	139.0	154.0	-15.0
Placebo			145.0	132.0
Placebo			142.0	151.0
Placebo			155.0	154.0
Placebo			132.0	132.0
Placebo			137.0	151.0
Placebo			139.0	154.0
Placebo		Week 12	161.0	142.0	19.0
Placebo		Week 12	152.0	153.0	-1.0
Placebo		Week 12	168.0	161.0	7.0
Placebo		Week 16	130.0	142.0	-12.0
Placebo		Week 16	137.0	153.0	-16.0
Placebo		Week 16	145.0	161.0	-16.0
Placebo		Week 2	147.0	142.0	5.0
Placebo		Week 2	146.0	153.0	-7.0
Placebo		Week 2	136.0	161.0	-25.0
Placebo		Week 20	144.0	142.0	2.0
Placebo		Week 20	171.0	153.0	18.0
Placebo		Week 20	171.0	161.0	10.0
Placebo		Week 24	131.0	142.0	-11.0
Placebo		Week 24	134.0	153.0	-19.0
Placebo		Week 24	130.0	161.0	-31.0
Placebo		Week 4	144.0	142.0	2.0
Placebo		Week 4	133.0	153.0	-20.0
Placebo		Week 4	145.0	161.0	-16.0
Placebo		Week 6	138.0	142.0	-4.0
Placebo		Week 6	146.0	153.0	-7.0
Placebo		Week 6	146.0	161.0	-15.0
Placebo		Week 8	140.0	142.0	-2.0
Placebo		Week 8	138.0	153.0	-15.0
Placebo		Week 8	130.0	161.0	-31.0
Placebo			140.0	142.0
Placebo			148.0	153.0
Placebo			148.0	161.0
Placebo			160.0	142.0
Placebo			176.0	153.0
Placebo			160.0	161.0
Xanomeline Low Dose		Week 2	190.0	160.0	30.0
Xanomeline Low Dose		Week 2	150.0	154.0	-4.0
Xanomeline Low Dose		Week 2	160.0	147.0	13.0
Xanomeline Low Dose			138.0	160.0
Xanomeline Low Dose			150.0	154.0
Xanomeline Low Dose			154.0	147.0
Placebo		Week 12	163.0	147.0	16.0
Placebo		Week 12	156.0	138.0	18.0
Placebo		Week 12	162.0	162.0	0.0
Placebo		Week 2	160.0	147.0	13.0
Placebo		Week 2	170.0	138.0	32.0
Placebo		Week 2	168.0	162.0	6.0
Placebo		Week 4	150.0	147.0	3.0
Placebo		Week 4	154.0	138.0	16.0
Placebo		Week 4	147.0	162.0	-15.0
Placebo		Week 6	140.0	147.0	-7.0
Placebo		Week 6	140.0	138.0	2.0
Placebo		Week 6	142.0	162.0	-20.0
Placebo		Week 8	140.0	147.0	-7.0
Placebo		Week 8	139.0	138.0	1.0
Placebo		Week 8	146.0	162.0	-16.0
Placebo			143.0	147.0
Placebo			133.0	138.0
Placebo			159.0	162.0
Placebo			132.0	147.0
Placebo			138.0	138.0
Placebo			135.0	162.0
Xanomeline Low Dose		Week 12	130.0	122.0	8.0
Xanomeline Low Dose		Week 12	128.0	126.0	2.0
Xanomeline Low Dose		Week 12	130.0	119.0	11.0
Xanomeline Low Dose		Week 16	122.0	122.0	0.0
Xanomeline Low Dose		Week 16	113.0	126.0	-13.0
Xanomeline Low Dose		Week 16	106.0	119.0	-13.0
Xanomeline Low Dose		Week 2	144.0	122.0	22.0
Xanomeline Low Dose		Week 2	138.0	126.0	12.0
Xanomeline Low Dose		Week 2	139.0	119.0	20.0
Xanomeline Low Dose		Week 4	113.0	122.0	-9.0
Xanomeline Low Dose		Week 4	122.0	126.0	-4.0
Xanomeline Low Dose		Week 4	122.0	119.0	3.0
Xanomeline Low Dose		Week 6	122.0	122.0	0.0
Xanomeline Low Dose		Week 6	130.0	126.0	4.0
Xanomeline Low Dose		Week 6	114.0	119.0	-5.0
Xanomeline Low Dose		Week 8	131.0	122.0	9.0
Xanomeline Low Dose		Week 8	127.0	126.0	1.0
Xanomeline Low Dose		Week 8	122.0	119.0	3.0
Xanomeline Low Dose			120.0	122.0
Xanomeline Low Dose			116.0	126.0
Xanomeline Low Dose			110.0	119.0
Xanomeline Low Dose			122.0	122.0
Xanomeline Low Dose			122.0	126.0
Xanomeline Low Dose			122.0	119.0
Xanomeline Low Dose		Week 12	135.0	178.0	-43.0
Xanomeline Low Dose		Week 12	140.0	153.0	-13.0
Xanomeline Low Dose		Week 12	128.0	138.0	-10.0
Xanomeline Low Dose		Week 16	145.0	178.0	-33.0
Xanomeline Low Dose		Week 16	153.0	153.0	0.0
Xanomeline Low Dose		Week 16	137.0	138.0	-1.0
Xanomeline Low Dose		Week 2	130.0	178.0	-48.0
Xanomeline Low Dose		Week 2	130.0	153.0	-23.0
Xanomeline Low Dose		Week 2	130.0	138.0	-8.0
Xanomeline Low Dose		Week 20	139.0	178.0	-39.0
Xanomeline Low Dose		Week 20	137.0	153.0	-16.0
Xanomeline Low Dose		Week 20	123.0	138.0	-15.0
Xanomeline Low Dose		Week 24	130.0	178.0	-48.0
Xanomeline Low Dose		Week 24	139.0	153.0	-14.0
Xanomeline Low Dose		Week 24	135.0	138.0	-3.0
Xanomeline Low Dose		Week 26	139.0	178.0	-39.0
Xanomeline Low Dose		Week 26	164.0	153.0	11.0
Xanomeline Low Dose		Week 26	140.0	138.0	2.0
Xanomeline Low Dose		Week 4	135.0	178.0	-43.0
Xanomeline Low Dose		Week 4	139.0	153.0	-14.0
Xanomeline Low Dose		Week 4	146.0	138.0	8.0
Xanomeline Low Dose		Week 6	123.0	178.0	-55.0
Xanomeline Low Dose		Week 6	130.0	153.0	-23.0
Xanomeline Low Dose		Week 6	131.0	138.0	-7.0
Xanomeline Low Dose		Week 8	138.0	178.0	-40.0
Xanomeline Low Dose		Week 8	149.0	153.0	-4.0
Xanomeline Low Dose		Week 8	131.0	138.0	-7.0
Xanomeline Low Dose			154.0	178.0
Xanomeline Low Dose			148.0	153.0
Xanomeline Low Dose			150.0	138.0
Xanomeline Low Dose			130.0	178.0
Xanomeline Low Dose			122.0	153.0
Xanomeline Low Dose			123.0	138.0
Xanomeline High Dose		Week 2	146.0	147.0	-1.0
Xanomeline High Dose		Week 2	150.0	145.0	5.0
Xanomeline High Dose		Week 2	138.0	147.0	-9.0
Xanomeline High Dose		Week 4	123.0	147.0	-24.0
Xanomeline High Dose		Week 4	112.0	145.0	-33.0
Xanomeline High Dose		Week 4	124.0	147.0	-23.0
Xanomeline High Dose		Week 6	138.0	147.0	-9.0
Xanomeline High Dose		Week 6	138.0	145.0	-7.0
Xanomeline High Dose		Week 6	139.0	147.0	-8.0
Xanomeline High Dose		Week 8	130.0	147.0	-17.0
Xanomeline High Dose		Week 8	131.0	145.0	-14.0
Xanomeline High Dose		Week 8	133.0	147.0	-14.0
Xanomeline High Dose			140.0	147.0
Xanomeline High Dose			139.0	145.0
Xanomeline High Dose			139.0	147.0
Placebo		Week 12	137.0	150.0	-13.0
Placebo		Week 12	142.0	159.0	-17.0
Placebo		Week 12	146.0	153.0	-7.0
Placebo		Week 16	150.0	150.0	0.0
Placebo		Week 16	155.0	159.0	-4.0
Placebo		Week 16	154.0	153.0	1.0
Placebo		Week 2	152.0	150.0	2.0
Placebo		Week 2	173.0	159.0	14.0
Placebo		Week 2	155.0	153.0	2.0
Placebo		Week 20	147.0	150.0	-3.0
Placebo		Week 20	137.0	159.0	-22.0
Placebo		Week 20	148.0	153.0	-5.0
Placebo		Week 24	176.0	150.0	26.0
Placebo		Week 24	199.0	159.0	40.0
Placebo		Week 24	186.0	153.0	33.0
Placebo		Week 26	130.0	150.0	-20.0
Placebo		Week 26	126.0	159.0	-33.0
Placebo		Week 26	145.0	153.0	-8.0
Placebo		Week 4	174.0	150.0	24.0
Placebo		Week 4	202.0	159.0	43.0
Placebo		Week 4	165.0	153.0	12.0
Placebo		Week 6	183.0	150.0	33.0
Placebo		Week 6	178.0	159.0	19.0
Placebo		Week 6	177.0	153.0	24.0
Placebo		Week 8	189.0	150.0	39.0
Placebo		Week 8	183.0	159.0	24.0
Placebo		Week 8	175.0	153.0	22.0
Placebo			168.0	150.0
Placebo			160.0	159.0
Placebo			156.0	153.0
Placebo			150.0	150.0
Placebo			150.0	159.0
Placebo			150.0	153.0
Xanomeline High Dose		Week 2	144.0	138.0	6.0
Xanomeline High Dose		Week 2	136.0	124.0	12.0
Xanomeline High Dose		Week 2	134.0	152.0	-18.0
Xanomeline High Dose		Week 4	121.0	138.0	-17.0
Xanomeline High Dose		Week 4	138.0	124.0	14.0
Xanomeline High Dose		Week 4	124.0	152.0	-28.0
Xanomeline High Dose		Week 6	129.0	138.0	-9.0
Xanomeline High Dose		Week 6	137.0	124.0	13.0
Xanomeline High Dose		Week 6	123.0	152.0	-29.0
Xanomeline High Dose		Week 8	147.0	138.0	9.0
Xanomeline High Dose		Week 8	138.0	124.0	14.0
Xanomeline High Dose		Week 8	146.0	152.0	-6.0
Xanomeline High Dose			129.0	138.0
Xanomeline High Dose			143.0	124.0
Xanomeline High Dose			139.0	152.0
Xanomeline High Dose			131.0	152.0
Xanomeline High Dose		Week 2	138.0	153.0	-15.0
Xanomeline High Dose		Week 2	138.0	153.0	-15.0
Xanomeline High Dose		Week 2	131.0	147.0	-16.0
Xanomeline High Dose		Week 4	155.0	153.0	2.0
Xanomeline High Dose		Week 4	146.0	153.0	-7.0
Xanomeline High Dose		Week 4	154.0	147.0	7.0
Xanomeline High Dose		Week 6	170.0	153.0	17.0
Xanomeline High Dose		Week 6	146.0	153.0	-7.0
Xanomeline High Dose		Week 6	163.0	147.0	16.0
Xanomeline High Dose			148.0	153.0
Xanomeline High Dose			136.0	153.0
Xanomeline High Dose			136.0	147.0
Xanomeline High Dose			131.0	153.0
Xanomeline High Dose			138.0	153.0
Xanomeline High Dose			146.0	147.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

TEMP

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	36.3	36.2	0.1
Placebo		Week 16	36.6	36.2	0.4
Placebo		Week 2	36.5	36.2	0.3
Placebo		Week 20	36.3	36.2	0.1
Placebo		Week 24	36.5	36.2	0.3
Placebo		Week 26	36.2	36.2	0.0
Placebo		Week 4	36.1	36.2	-0.1
Placebo		Week 6	36.3	36.2	0.1
Placebo		Week 8	36.7	36.2	0.5
Placebo			35.9	36.2
Placebo			36.4	36.2
Placebo		Week 2	36.9	36.3	0.7
Placebo			36.4	36.3
Xanomeline High Dose		Week 12	36.8	37.0	-0.2
Xanomeline High Dose		Week 16	36.6	37.0	-0.4
Xanomeline High Dose		Week 2	37.2	37.0	0.2
Xanomeline High Dose		Week 20	36.4	37.0	-0.6
Xanomeline High Dose		Week 24	37.1	37.0	0.1
Xanomeline High Dose		Week 26	36.6	37.0	-0.4
Xanomeline High Dose		Week 4	36.9	37.0	-0.1
Xanomeline High Dose		Week 6	36.5	37.0	-0.5
Xanomeline High Dose		Week 8	36.7	37.0	-0.3
Xanomeline High Dose			36.8	37.0
Xanomeline High Dose			36.8	37.0
Xanomeline Low Dose			36.7	37.1
Xanomeline High Dose		Week 12	37.1	36.9	0.1
Xanomeline High Dose		Week 16	36.9	36.9	0.0
Xanomeline High Dose		Week 2	36.6	36.9	-0.4
Xanomeline High Dose		Week 20	36.9	36.9	-0.0
Xanomeline High Dose		Week 24	36.7	36.9	-0.2
Xanomeline High Dose		Week 26	36.6	36.9	-0.4
Xanomeline High Dose		Week 4	36.6	36.9	-0.3
Xanomeline High Dose		Week 6	37.1	36.9	0.1
Xanomeline High Dose		Week 8	36.7	36.9	-0.2
Xanomeline High Dose			36.8	36.9
Placebo		Week 2	37.2	36.4	0.8
Placebo			36.1	36.4
Xanomeline Low Dose		Week 12	36.4	36.4	-0.0
Xanomeline Low Dose		Week 16	36.7	36.4	0.3
Xanomeline Low Dose		Week 2	36.5	36.4	0.1
Xanomeline Low Dose		Week 20	36.4	36.4	0.0
Xanomeline Low Dose		Week 24	37.0	36.4	0.6
Xanomeline Low Dose		Week 26	36.6	36.4	0.1
Xanomeline Low Dose		Week 4	34.3	36.4	-2.2
Xanomeline Low Dose		Week 6	36.4	36.4	0.0
Xanomeline Low Dose		Week 8	36.8	36.4	0.4
Xanomeline Low Dose			36.6	36.4
Xanomeline Low Dose			36.7	36.4
Xanomeline Low Dose		Week 2	36.7	36.7	0.0
Xanomeline Low Dose		Week 4	36.5	36.7	-0.2
Xanomeline Low Dose		Week 6	36.4	36.7	-0.2
Xanomeline Low Dose		Week 8	36.4	36.7	-0.2
Xanomeline Low Dose			36.3	36.7
Xanomeline Low Dose			36.3	36.7
Placebo		Week 12	36.7	36.4	0.3
Placebo		Week 16	36.2	36.4	-0.2
Placebo		Week 2	36.7	36.4	0.3
Placebo		Week 20	37.7	36.4	1.3
Placebo		Week 24	37.0	36.4	0.6
Placebo		Week 26	36.8	36.4	0.4
Placebo		Week 4	36.8	36.4	0.4
Placebo		Week 6	36.8	36.4	0.4
Placebo		Week 8	36.7	36.4	0.3
Placebo			36.4	36.4
Placebo			36.6	36.4
Placebo		Week 12	36.8	36.0	0.8
Placebo		Week 16	36.3	36.0	0.3
Placebo		Week 2	36.8	36.0	0.8
Placebo		Week 20	36.3	36.0	0.3
Placebo		Week 24	36.2	36.0	0.2
Placebo		Week 26	36.2	36.0	0.2
Placebo		Week 4	36.8	36.0	0.8
Placebo		Week 6	36.6	36.0	0.6
Placebo		Week 8	35.6	36.0	-0.4
Placebo			36.4	36.0
Placebo			36.7	36.0
Xanomeline High Dose		Week 12	36.9	36.4	0.5
Xanomeline High Dose		Week 16	36.8	36.4	0.4
Xanomeline High Dose		Week 2	36.6	36.4	0.2
Xanomeline High Dose		Week 20	36.4	36.4	0.0
Xanomeline High Dose		Week 24	37.2	36.4	0.8
Xanomeline High Dose		Week 4	36.3	36.4	-0.1
Xanomeline High Dose		Week 6	35.9	36.4	-0.5
Xanomeline High Dose		Week 8	36.6	36.4	0.2
Xanomeline High Dose			36.9	36.4
Xanomeline High Dose			36.4	36.4
Xanomeline High Dose		Week 2	36.6	36.4	0.2
Xanomeline High Dose		Week 4	36.3	36.4	-0.1
Xanomeline High Dose			36.6	36.4
Xanomeline High Dose			37.0	36.4
Xanomeline High Dose		Week 12	36.6	36.6	0.0
Xanomeline High Dose		Week 16	36.7	36.6	0.1
Xanomeline High Dose		Week 2	36.9	36.6	0.4
Xanomeline High Dose		Week 20	36.4	36.6	-0.1
Xanomeline High Dose		Week 24	36.4	36.6	-0.1
Xanomeline High Dose		Week 26	36.4	36.6	-0.2
Xanomeline High Dose		Week 4	37.1	36.6	0.5
Xanomeline High Dose		Week 6	36.6	36.6	0.0
Xanomeline High Dose		Week 8	36.6	36.6	0.0
Xanomeline High Dose			36.5	36.6
Xanomeline High Dose			36.6	36.6
Placebo		Week 12	36.8	36.9	-0.2
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.8	36.9	-0.1
Placebo		Week 20	36.4	36.9	-0.5
Placebo		Week 24	37.2	36.9	0.2
Placebo		Week 4	37.2	36.9	0.3
Placebo		Week 6	36.7	36.9	-0.2
Placebo		Week 8	36.8	36.9	-0.1
Placebo			36.8	36.9
Placebo			37.2	36.9
Xanomeline High Dose		Week 2	37.1	36.6	0.5
Xanomeline High Dose		Week 4	36.6	36.6	0.0
Xanomeline High Dose			36.6	36.6
Xanomeline High Dose			37.2	36.6
Xanomeline Low Dose		Week 2	36.3	36.3	0.0
Xanomeline Low Dose		Week 4	36.0	36.3	-0.3
Xanomeline Low Dose			36.4	36.3
Xanomeline Low Dose			37.0	36.3
Xanomeline Low Dose		Week 12	36.8	36.8	0.0
Xanomeline Low Dose		Week 16	36.2	36.8	-0.6
Xanomeline Low Dose		Week 2	36.4	36.8	-0.4
Xanomeline Low Dose		Week 20	37.2	36.8	0.3
Xanomeline Low Dose		Week 24	36.8	36.8	0.0
Xanomeline Low Dose		Week 26	37.0	36.8	0.2
Xanomeline Low Dose		Week 4	37.0	36.8	0.2
Xanomeline Low Dose		Week 6	37.0	36.8	0.2
Xanomeline Low Dose		Week 8	37.2	36.8	0.3
Xanomeline Low Dose			36.6	36.8
Xanomeline Low Dose			36.6	36.8
Placebo		Week 12	36.7	36.9	-0.2
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.6	36.9	-0.3
Placebo		Week 20	36.4	36.9	-0.5
Placebo		Week 24	36.7	36.9	-0.2
Placebo		Week 26	36.3	36.9	-0.6
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.3	36.9	-0.6
Placebo		Week 8	36.4	36.9	-0.5
Placebo			36.5	36.9
Xanomeline Low Dose		Week 2	36.1	36.6	-0.5
Xanomeline Low Dose		Week 4	36.6	36.6	0.0
Xanomeline Low Dose		Week 6	35.7	36.6	-0.9
Xanomeline Low Dose		Week 8	36.2	36.6	-0.3
Xanomeline Low Dose			36.4	36.6
Xanomeline Low Dose			35.9	36.6
Placebo		Week 12	36.2	36.8	-0.6
Placebo		Week 16	36.7	36.8	-0.1
Placebo		Week 2	36.3	36.8	-0.5
Placebo		Week 20	36.4	36.8	-0.4
Placebo		Week 24	36.9	36.8	0.2
Placebo		Week 26	36.4	36.8	-0.3
Placebo		Week 4	36.6	36.8	-0.2
Placebo		Week 6	36.2	36.8	-0.6
Placebo		Week 8	36.5	36.8	-0.3
Placebo			36.2	36.8
Placebo			36.2	36.8
Xanomeline High Dose		Week 12	36.8	37.0	-0.2
Xanomeline High Dose		Week 16	36.7	37.0	-0.3
Xanomeline High Dose		Week 2	37.2	37.0	0.2
Xanomeline High Dose		Week 20	36.7	37.0	-0.3
Xanomeline High Dose		Week 24	36.1	37.0	-0.9
Xanomeline High Dose		Week 4	36.7	37.0	-0.3
Xanomeline High Dose		Week 6	37.2	37.0	0.2
Xanomeline High Dose		Week 8	36.8	37.0	-0.2
Xanomeline High Dose			36.3	37.0
Xanomeline High Dose			36.4	37.0
Xanomeline High Dose		Week 12	36.5	36.2	0.3
Xanomeline High Dose		Week 2	36.3	36.2	0.1
Xanomeline High Dose		Week 4	36.4	36.2	0.2
Xanomeline High Dose		Week 6	36.4	36.2	0.2
Xanomeline High Dose		Week 8	36.4	36.2	0.2
Xanomeline High Dose			36.6	36.2
Xanomeline High Dose			36.7	36.2
Xanomeline High Dose		Week 12	36.9	37.1	-0.2
Xanomeline High Dose		Week 16	36.3	37.1	-0.8
Xanomeline High Dose		Week 2	36.6	37.1	-0.5
Xanomeline High Dose		Week 20	36.8	37.1	-0.3
Xanomeline High Dose		Week 24	36.4	37.1	-0.7
Xanomeline High Dose		Week 26	36.8	37.1	-0.3
Xanomeline High Dose		Week 4	36.6	37.1	-0.5
Xanomeline High Dose		Week 6	36.5	37.1	-0.6
Xanomeline High Dose		Week 8	37.3	37.1	0.2
Xanomeline High Dose			36.9	37.1
Xanomeline Low Dose		Week 12	36.5	36.4	0.1
Xanomeline Low Dose		Week 2	35.9	36.4	-0.5
Xanomeline Low Dose		Week 4	36.5	36.4	0.1
Xanomeline Low Dose		Week 6	36.3	36.4	-0.1
Xanomeline Low Dose		Week 8	36.2	36.4	-0.2
Xanomeline Low Dose			36.7	36.4
Xanomeline Low Dose			36.6	36.4
Xanomeline High Dose		Week 12	36.6	35.7	0.9
Xanomeline High Dose		Week 2	36.8	35.7	1.1
Xanomeline High Dose		Week 4	36.2	35.7	0.5
Xanomeline High Dose		Week 6	36.6	35.7	0.9
Xanomeline High Dose		Week 8	36.7	35.7	1.0
Xanomeline High Dose			36.6	35.7
Xanomeline High Dose			35.8	35.7
Xanomeline Low Dose		Week 12	36.8	37.2	-0.4
Xanomeline Low Dose		Week 16	36.5	37.2	-0.7
Xanomeline Low Dose		Week 2	36.6	37.2	-0.6
Xanomeline Low Dose		Week 20	37.1	37.2	-0.1
Xanomeline Low Dose		Week 24	36.9	37.2	-0.2
Xanomeline Low Dose		Week 26	36.5	37.2	-0.7
Xanomeline Low Dose		Week 4	36.5	37.2	-0.7
Xanomeline Low Dose		Week 6	36.8	37.2	-0.4
Xanomeline Low Dose		Week 8	36.4	37.2	-0.7
Xanomeline Low Dose			36.9	37.2
Xanomeline Low Dose			36.3	37.2
Xanomeline Low Dose		Week 12	36.6	36.4	0.2
Xanomeline Low Dose		Week 16	36.3	36.4	-0.1
Xanomeline Low Dose		Week 2	36.9	36.4	0.5
Xanomeline Low Dose		Week 20	36.6	36.4	0.2
Xanomeline Low Dose		Week 24	36.7	36.4	0.3
Xanomeline Low Dose		Week 26	36.7	36.4	0.3
Xanomeline Low Dose		Week 4	36.2	36.4	-0.2
Xanomeline Low Dose		Week 6	36.7	36.4	0.3
Xanomeline Low Dose		Week 8	36.2	36.4	-0.2
Xanomeline Low Dose			36.2	36.4
Xanomeline Low Dose			36.6	36.4
Xanomeline Low Dose		Week 2	36.6	37.3	-0.7
Xanomeline Low Dose			37.0	37.3
Placebo		Week 12	36.9	36.4	0.5
Placebo		Week 16	36.5	36.4	0.1
Placebo		Week 2	37.1	36.4	0.7
Placebo		Week 20	36.8	36.4	0.3
Placebo		Week 24	36.6	36.4	0.1
Placebo		Week 4	37.2	36.4	0.7
Placebo		Week 6	36.2	36.4	-0.2
Placebo		Week 8	37.2	36.4	0.7
Placebo			37.2	36.4
Placebo			36.7	36.4
Placebo		Week 12	36.9	36.8	0.1
Placebo		Week 16	37.1	36.8	0.3
Placebo		Week 2	37.5	36.8	0.7
Placebo		Week 20	36.7	36.8	-0.1
Placebo		Week 24	36.6	36.8	-0.2
Placebo		Week 26	37.1	36.8	0.3
Placebo		Week 4	37.1	36.8	0.3
Placebo		Week 6	37.5	36.8	0.7
Placebo		Week 8	36.5	36.8	-0.3
Placebo			36.7	36.8
Placebo			36.8	36.8
Xanomeline High Dose		Week 12	36.9	36.5	0.4
Xanomeline High Dose		Week 16	36.4	36.5	-0.1
Xanomeline High Dose		Week 2	36.8	36.5	0.3
Xanomeline High Dose		Week 20	36.7	36.5	0.2
Xanomeline High Dose		Week 24	36.4	36.5	-0.1
Xanomeline High Dose		Week 26	36.4	36.5	-0.1
Xanomeline High Dose		Week 4	36.7	36.5	0.2
Xanomeline High Dose		Week 6	36.8	36.5	0.3
Xanomeline High Dose		Week 8	36.4	36.5	-0.1
Xanomeline High Dose			36.7	36.5
Xanomeline High Dose			36.4	36.5
Placebo		Week 2	36.4	36.6	-0.2
Placebo		Week 12	37.1	36.5	0.6
Placebo		Week 16	36.4	36.5	-0.1
Placebo		Week 2	36.8	36.5	0.3
Placebo		Week 20	37.2	36.5	0.7
Placebo		Week 24	36.6	36.5	0.1
Placebo		Week 26	37.2	36.5	0.7
Placebo		Week 4	36.7	36.5	0.2
Placebo		Week 6	37.0	36.5	0.5
Placebo		Week 8	36.6	36.5	0.1
Placebo			36.4	36.5
Placebo			36.6	36.5
Placebo		Week 12	36.5	36.7	-0.2
Placebo		Week 16	36.8	36.7	0.1
Placebo		Week 2	36.5	36.7	-0.2
Placebo		Week 20	35.9	36.7	-0.7
Placebo		Week 24	36.3	36.7	-0.4
Placebo		Week 26	36.5	36.7	-0.2
Placebo		Week 4	37.6	36.7	0.9
Placebo		Week 6	36.9	36.7	0.2
Placebo		Week 8	35.9	36.7	-0.8
Placebo			36.6	36.7
Placebo			36.4	36.7
Xanomeline Low Dose		Week 2	36.9	36.9	0.0
Xanomeline Low Dose		Week 4	36.4	36.9	-0.5
Xanomeline Low Dose		Week 6	36.8	36.9	-0.2
Placebo		Week 12	37.1	36.2	0.9
Placebo		Week 16	36.7	36.2	0.5
Placebo		Week 2	35.4	36.2	-0.7
Placebo		Week 20	36.9	36.2	0.8
Placebo		Week 24	37.1	36.2	0.9
Placebo		Week 26	37.0	36.2	0.8
Placebo		Week 4	36.8	36.2	0.6
Placebo		Week 6	36.5	36.2	0.3
Placebo		Week 8	36.3	36.2	0.1
Placebo			35.9	36.2
Placebo			36.5	36.2
Xanomeline Low Dose		Week 12	36.5	36.7	-0.2
Xanomeline Low Dose		Week 16	36.4	36.7	-0.3
Xanomeline Low Dose		Week 2	36.5	36.7	-0.2
Xanomeline Low Dose		Week 20	37.4	36.7	0.8
Xanomeline Low Dose		Week 24	36.4	36.7	-0.3
Xanomeline Low Dose		Week 26	36.9	36.7	0.3
Xanomeline Low Dose		Week 4	36.7	36.7	0.0
Xanomeline Low Dose		Week 6	36.9	36.7	0.2
Xanomeline Low Dose		Week 8	36.4	36.7	-0.3
Xanomeline Low Dose			36.4	36.7
Xanomeline Low Dose			36.6	36.7
Xanomeline High Dose		Week 2	36.9	36.9	-0.0
Xanomeline High Dose		Week 4	36.7	36.9	-0.2
Xanomeline High Dose			36.9	36.9
Xanomeline High Dose			37.0	36.9
Xanomeline Low Dose		Week 2	36.2	36.6	-0.3
Xanomeline Low Dose		Week 4	36.0	36.6	-0.6
Xanomeline Low Dose		Week 6	36.7	36.6	0.1
Xanomeline Low Dose		Week 8	36.2	36.6	-0.3
Xanomeline Low Dose			36.0	36.6
Xanomeline Low Dose			36.4	36.6
Placebo		Week 12	37.0	37.1	-0.1
Placebo		Week 16	37.1	37.1	-0.0
Placebo		Week 2	37.0	37.1	-0.1
Placebo		Week 20	37.4	37.1	0.3
Placebo		Week 24	37.2	37.1	0.1
Placebo		Week 26	37.6	37.1	0.5
Placebo		Week 4	36.0	37.1	-1.1
Placebo		Week 6	37.0	37.1	-0.1
Placebo		Week 8	37.0	37.1	-0.1
Placebo			36.9	37.1
Placebo			36.7	37.1
Xanomeline High Dose		Week 12	36.9	37.1	-0.2
Xanomeline High Dose		Week 2	36.9	37.1	-0.2
Xanomeline High Dose		Week 4	36.9	37.1	-0.2
Xanomeline High Dose		Week 6	36.3	37.1	-0.8
Xanomeline High Dose		Week 8	36.7	37.1	-0.4
Xanomeline High Dose			36.9	37.1
Xanomeline High Dose			36.9	37.1
Xanomeline Low Dose		Week 12	36.4	36.4	0.0
Xanomeline Low Dose		Week 2	36.4	36.4	0.0
Xanomeline Low Dose		Week 4	36.9	36.4	0.5
Xanomeline Low Dose		Week 6	36.6	36.4	0.1
Xanomeline Low Dose		Week 8	36.6	36.4	0.1
Xanomeline Low Dose			36.9	36.4
Xanomeline Low Dose			37.1	36.4
Placebo		Week 2	36.7	36.7	0.0
Placebo		Week 4	36.6	36.7	-0.1
Placebo			36.4	36.7
Placebo			36.8	36.7
Placebo		Week 12	37.0	36.7	0.3
Placebo		Week 16	37.0	36.7	0.3
Placebo		Week 2	37.0	36.7	0.3
Placebo		Week 20	37.0	36.7	0.3
Placebo		Week 24	37.0	36.7	0.3
Placebo		Week 26	36.9	36.7	0.2
Placebo		Week 4	36.6	36.7	-0.1
Placebo		Week 6	36.6	36.7	-0.1
Placebo		Week 8	36.9	36.7	0.2
Placebo			36.8	36.7
Placebo			36.2	36.7
Xanomeline Low Dose		Week 12	36.8	36.2	0.6
Xanomeline Low Dose		Week 16	37.0	36.2	0.8
Xanomeline Low Dose		Week 2	37.0	36.2	0.8
Xanomeline Low Dose		Week 4	37.1	36.2	0.9
Xanomeline Low Dose		Week 6	36.9	36.2	0.7
Xanomeline Low Dose		Week 8	37.0	36.2	0.8
Xanomeline Low Dose			36.7	36.2
Xanomeline Low Dose			37.0	36.2
Xanomeline Low Dose		Week 2	36.9	37.1	-0.2
Xanomeline Low Dose		Week 4	36.7	37.1	-0.4
Xanomeline Low Dose		Week 6	36.0	37.1	-1.1
Xanomeline Low Dose			36.7	37.1
Placebo		Week 12	37.1	35.9	1.2
Placebo		Week 16	37.2	35.9	1.3
Placebo		Week 2	36.8	35.9	0.9
Placebo		Week 20	36.9	35.9	1.0
Placebo		Week 24	37.1	35.9	1.2
Placebo		Week 26	36.7	35.9	0.8
Placebo		Week 4	36.0	35.9	0.1
Placebo		Week 6	36.9	35.9	1.0
Placebo		Week 8	36.6	35.9	0.7
Placebo			36.8	35.9
Placebo			35.8	35.9
Xanomeline High Dose		Week 12	36.6	36.8	-0.2
Xanomeline High Dose		Week 16	36.8	36.8	0.0
Xanomeline High Dose		Week 2	36.6	36.8	-0.2
Xanomeline High Dose		Week 20	37.1	36.8	0.3
Xanomeline High Dose		Week 24	37.1	36.8	0.3
Xanomeline High Dose		Week 4	36.6	36.8	-0.2
Xanomeline High Dose		Week 6	36.7	36.8	-0.1
Xanomeline High Dose		Week 8	36.3	36.8	-0.5
Xanomeline High Dose			36.8	36.8
Xanomeline High Dose			36.8	36.8
Xanomeline High Dose		Week 12	37.1	36.7	0.4
Xanomeline High Dose		Week 16	37.1	36.7	0.4
Xanomeline High Dose		Week 2	37.1	36.7	0.4
Xanomeline High Dose		Week 4	37.2	36.7	0.5
Xanomeline High Dose		Week 6	37.0	36.7	0.3
Xanomeline High Dose		Week 8	36.8	36.7	0.1
Xanomeline High Dose			36.7	36.7
Xanomeline High Dose			36.6	36.7
Placebo		Week 12	37.0	37.0	0.0
Placebo		Week 16	36.9	37.0	-0.1
Placebo		Week 2	36.4	37.0	-0.6
Placebo		Week 20	37.0	37.0	0.0
Placebo		Week 24	36.6	37.0	-0.4
Placebo		Week 26	37.7	37.0	0.7
Placebo		Week 4	36.3	37.0	-0.7
Placebo		Week 6	36.6	37.0	-0.4
Placebo		Week 8	36.4	37.0	-0.6
Placebo			36.7	37.0
Placebo			36.3	37.0
Xanomeline High Dose		Week 2	36.7	37.0	-0.3
Xanomeline High Dose		Week 4	36.0	37.0	-1.0
Xanomeline High Dose			36.8	37.0
Xanomeline High Dose			37.1	37.0
Xanomeline Low Dose		Week 12	36.6	36.6	0.0
Xanomeline Low Dose		Week 16	36.6	36.6	0.0
Xanomeline Low Dose		Week 2	36.6	36.6	0.0
Xanomeline Low Dose		Week 20	37.6	36.6	1.0
Xanomeline Low Dose		Week 24	37.1	36.6	0.5
Xanomeline Low Dose		Week 26	37.0	36.6	0.4
Xanomeline Low Dose		Week 4	36.8	36.6	0.2
Xanomeline Low Dose		Week 6	36.0	36.6	-0.6
Xanomeline Low Dose		Week 8	36.7	36.6	0.1
Xanomeline Low Dose			36.0	36.6
Xanomeline Low Dose			36.8	36.6
Xanomeline High Dose		Week 12	37.2	37.4	-0.2
Xanomeline High Dose		Week 16	37.1	37.4	-0.3
Xanomeline High Dose		Week 2	37.0	37.4	-0.4
Xanomeline High Dose		Week 20	37.0	37.4	-0.4
Xanomeline High Dose		Week 24	37.0	37.4	-0.4
Xanomeline High Dose		Week 26	37.0	37.4	-0.4
Xanomeline High Dose		Week 4	37.3	37.4	-0.1
Xanomeline High Dose		Week 6	37.0	37.4	-0.4
Xanomeline High Dose		Week 8	37.3	37.4	-0.1
Xanomeline High Dose			36.7	37.4
Xanomeline High Dose			37.1	37.4
Xanomeline High Dose		Week 2	36.7	36.8	-0.1
Xanomeline High Dose		Week 4	36.7	36.8	-0.1
Xanomeline High Dose			37.1	36.8
Xanomeline High Dose			36.9	36.8
Xanomeline Low Dose		Week 2	36.7	36.4	0.2
Xanomeline Low Dose			36.6	36.4
Placebo		Week 12	36.8	36.6	0.2
Placebo		Week 16	36.9	36.6	0.3
Placebo		Week 2	36.9	36.6	0.3
Placebo		Week 4	36.8	36.6	0.2
Placebo		Week 6	36.9	36.6	0.3
Placebo		Week 8	36.7	36.6	0.1
Placebo			36.7	36.6
Placebo			36.7	36.6
Xanomeline High Dose		Week 2	36.4	36.6	-0.1
Xanomeline High Dose		Week 4	36.7	36.6	0.1
Xanomeline High Dose			36.8	36.6
Xanomeline Low Dose		Week 2	36.7	36.8	-0.1
Xanomeline Low Dose			36.4	36.8
Xanomeline High Dose		Week 4	36.1	36.6	-0.5
Xanomeline High Dose		Week 6	36.6	36.6	0.0
Xanomeline High Dose		Week 8	36.7	36.6	0.1
Xanomeline High Dose			36.9	36.6
Xanomeline High Dose			36.3	36.6
Xanomeline High Dose		Week 2	35.8	36.3	-0.5
Xanomeline High Dose		Week 4	36.2	36.3	-0.1
Xanomeline High Dose		Week 6	36.7	36.3	0.3
Xanomeline High Dose			36.1	36.3
Xanomeline High Dose			36.8	36.3
Xanomeline High Dose		Week 12	36.6	37.0	-0.4
Xanomeline High Dose		Week 2	36.3	37.0	-0.7
Xanomeline High Dose		Week 4	36.7	37.0	-0.3
Xanomeline High Dose		Week 6	36.4	37.0	-0.6
Xanomeline High Dose		Week 8	36.7	37.0	-0.3
Xanomeline High Dose			36.4	37.0
Xanomeline High Dose			36.6	37.0
Xanomeline Low Dose		Week 12	36.8	36.3	0.5
Xanomeline Low Dose		Week 16	36.6	36.3	0.2
Xanomeline Low Dose		Week 2	36.6	36.3	0.2
Xanomeline Low Dose		Week 20	37.0	36.3	0.7
Xanomeline Low Dose		Week 4	36.9	36.3	0.6
Xanomeline Low Dose		Week 6	36.7	36.3	0.3
Xanomeline Low Dose		Week 8	36.9	36.3	0.6
Xanomeline Low Dose			36.6	36.3
Xanomeline Low Dose			36.4	36.3
Xanomeline Low Dose		Week 2	36.8	36.8	0.0
Xanomeline Low Dose		Week 4	36.7	36.8	-0.1
Xanomeline Low Dose		Week 6	36.7	36.8	-0.1
Xanomeline Low Dose		Week 8	36.5	36.8	-0.3
Xanomeline Low Dose			36.8	36.8
Xanomeline Low Dose			36.4	36.8
Placebo		Week 12	36.4	37.1	-0.6
Placebo		Week 16	36.7	37.1	-0.4
Placebo		Week 2	36.6	37.1	-0.5
Placebo		Week 20	36.8	37.1	-0.2
Placebo		Week 24	36.6	37.1	-0.5
Placebo		Week 26	36.8	37.1	-0.3
Placebo		Week 4	36.6	37.1	-0.5
Placebo		Week 6	36.3	37.1	-0.7
Placebo		Week 8	36.9	37.1	-0.2
Placebo			36.9	37.1
Placebo			36.7	37.1
Xanomeline Low Dose		Week 12	36.7	36.4	0.3
Xanomeline Low Dose		Week 16	36.7	36.4	0.3
Xanomeline Low Dose		Week 2	36.7	36.4	0.3
Xanomeline Low Dose		Week 20	36.1	36.4	-0.3
Xanomeline Low Dose		Week 24	36.7	36.4	0.3
Xanomeline Low Dose		Week 26	36.3	36.4	-0.1
Xanomeline Low Dose		Week 4	36.9	36.4	0.5
Xanomeline Low Dose		Week 6	36.8	36.4	0.4
Xanomeline Low Dose		Week 8	37.1	36.4	0.7
Xanomeline Low Dose			36.8	36.4
Xanomeline Low Dose			36.7	36.4
Placebo		Week 12	36.9	36.9	0.0
Placebo		Week 16	36.8	36.9	-0.1
Placebo		Week 2	36.3	36.9	-0.6
Placebo		Week 20	36.7	36.9	-0.2
Placebo		Week 24	36.7	36.9	-0.2
Placebo		Week 26	36.7	36.9	-0.2
Placebo		Week 4	36.4	36.9	-0.5
Placebo		Week 6	36.7	36.9	-0.2
Placebo		Week 8	36.8	36.9	-0.1
Placebo			36.7	36.9
Placebo			36.3	36.9
Xanomeline Low Dose		Week 12	36.7	36.7	-0.0
Xanomeline Low Dose		Week 16	36.7	36.7	-0.0
Xanomeline Low Dose		Week 2	36.7	36.7	-0.0
Xanomeline Low Dose		Week 20	36.7	36.7	-0.0
Xanomeline Low Dose		Week 24	36.8	36.7	0.1
Xanomeline Low Dose		Week 26	35.6	36.7	-1.2
Xanomeline Low Dose		Week 4	36.6	36.7	-0.1
Xanomeline Low Dose		Week 6	36.7	36.7	-0.0
Xanomeline Low Dose		Week 8	36.8	36.7	0.1
Xanomeline Low Dose			36.6	36.7
Xanomeline Low Dose			36.8	36.7
Placebo		Week 2	35.7	36.3	-0.7
Placebo			35.9	36.3
Xanomeline High Dose		Week 2	36.6	36.4	0.1
Xanomeline High Dose		Week 4	36.6	36.4	0.1
Xanomeline High Dose		Week 6	36.7	36.4	0.2
Xanomeline High Dose			36.4	36.4
Xanomeline High Dose			36.9	36.4
Placebo		Week 2	36.7	36.6	0.1
Placebo		Week 4	36.6	36.6	0.0
Placebo		Week 6	36.3	36.6	-0.3
Placebo		Week 8	36.7	36.6	0.1
Placebo			36.4	36.6
Placebo			36.8	36.6
Xanomeline High Dose		Week 2	35.9	36.1	-0.1
Xanomeline High Dose		Week 4	36.4	36.1	0.3
Xanomeline High Dose		Week 6	36.5	36.1	0.4
Xanomeline High Dose		Week 8	36.8	36.1	0.8
Xanomeline High Dose			36.6	36.1
Xanomeline High Dose			36.7	36.1
Xanomeline Low Dose		Week 2	36.7	36.3	0.3
Xanomeline Low Dose		Week 4	36.7	36.3	0.3
Xanomeline Low Dose			36.4	36.3
Xanomeline Low Dose		Week 2	36.7	36.4	0.2
Xanomeline Low Dose		Week 4	36.8	36.4	0.4
Xanomeline Low Dose		Week 6	37.1	36.4	0.6
Xanomeline Low Dose		Week 8	36.8	36.4	0.3
Xanomeline Low Dose			36.6	36.4
Xanomeline Low Dose			36.9	36.4
Xanomeline High Dose		Week 2	37.1	36.6	0.5
Xanomeline High Dose		Week 4	37.4	36.6	0.8
Xanomeline High Dose		Week 6	37.2	36.6	0.6
Xanomeline High Dose		Week 8	37.1	36.6	0.5
Xanomeline High Dose			37.1	36.6
Xanomeline High Dose			36.9	36.6
Placebo		Week 12	36.7	36.9	-0.3
Placebo		Week 16	36.3	36.9	-0.6
Placebo		Week 2	36.8	36.9	-0.1
Placebo		Week 20	36.8	36.9	-0.2
Placebo		Week 24	36.7	36.9	-0.3
Placebo		Week 26	36.7	36.9	-0.3
Placebo		Week 6	37.0	36.9	0.1
Placebo		Week 8	36.9	36.9	-0.0
Placebo			36.7	36.9
Placebo		Week 12	36.7	36.4	0.2
Placebo		Week 16	36.9	36.4	0.5
Placebo		Week 2	36.6	36.4	0.1
Placebo		Week 20	36.7	36.4	0.2
Placebo		Week 24	36.9	36.4	0.5
Placebo		Week 4	36.3	36.4	-0.1
Placebo		Week 6	36.8	36.4	0.4
Placebo		Week 8	36.8	36.4	0.3
Placebo			36.3	36.4
Placebo			36.7	36.4
Placebo		Week 2	36.6	37.1	-0.5
Placebo		Week 4	36.9	37.1	-0.1
Placebo		Week 6	36.8	37.1	-0.2
Placebo			36.9	37.1
Placebo		Week 12	36.9	36.9	0.0
Placebo		Week 16	36.7	36.9	-0.2
Placebo		Week 2	36.7	36.9	-0.2
Placebo		Week 20	36.4	36.9	-0.5
Placebo		Week 4	36.8	36.9	-0.1
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	37.1	36.9	0.2
Placebo			36.8	36.9
Placebo			37.1	36.9
Xanomeline Low Dose		Week 2	36.9	37.0	-0.1
Xanomeline Low Dose			36.9	37.0
Placebo		Week 12	37.0	36.9	0.1
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.9	36.9	0.0
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	36.9	36.9	0.0
Placebo			36.9	36.9
Placebo			36.9	36.9
Placebo		Week 2	36.9	36.9	-0.0
Placebo			36.9	36.9
Xanomeline High Dose		Week 12	36.9	36.8	0.1
Xanomeline High Dose		Week 16	36.9	36.8	0.1
Xanomeline High Dose		Week 2	37.0	36.8	0.2
Xanomeline High Dose		Week 20	36.9	36.8	0.1
Xanomeline High Dose		Week 24	36.8	36.8	0.0
Xanomeline High Dose		Week 26	37.1	36.8	0.3
Xanomeline High Dose		Week 4	36.9	36.8	0.1
Xanomeline High Dose		Week 6	36.9	36.8	0.1
Xanomeline High Dose		Week 8	36.9	36.8	0.1
Xanomeline High Dose			36.9	36.8
Xanomeline High Dose			37.0	36.8
Xanomeline High Dose		Week 12	36.9	37.0	-0.1
Xanomeline High Dose		Week 2	36.9	37.0	-0.1
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose		Week 6	36.9	37.0	-0.1
Xanomeline High Dose		Week 8	36.9	37.0	-0.1
Xanomeline High Dose			36.9	37.0
Xanomeline High Dose			36.9	37.0
Placebo		Week 12	36.9	36.8	0.1
Placebo		Week 16	36.9	36.8	0.1
Placebo		Week 2	36.9	36.8	0.1
Placebo		Week 20	36.9	36.8	0.1
Placebo		Week 24	37.0	36.8	0.2
Placebo		Week 26	37.0	36.8	0.2
Placebo		Week 4	36.9	36.8	0.1
Placebo		Week 6	36.9	36.8	0.1
Placebo		Week 8	36.9	36.8	0.1
Placebo			36.9	36.8
Placebo			36.9	36.8
Xanomeline Low Dose		Week 12	36.9	36.9	0.0
Xanomeline Low Dose		Week 16	37.0	36.9	0.1
Xanomeline Low Dose		Week 2	36.9	36.9	0.0
Xanomeline Low Dose		Week 20	36.9	36.9	0.0
Xanomeline Low Dose		Week 24	36.9	36.9	0.0
Xanomeline Low Dose		Week 4	36.9	36.9	0.0
Xanomeline Low Dose		Week 6	36.9	36.9	0.0
Xanomeline Low Dose		Week 8	36.9	36.9	0.0
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose			36.9	36.9
Xanomeline High Dose		Week 2	37.0	36.9	0.1
Xanomeline High Dose			36.9	36.9
Xanomeline High Dose		Week 12	36.9	36.9	0.0
Xanomeline High Dose		Week 2	36.9	36.9	0.0
Xanomeline High Dose		Week 4	36.9	36.9	0.0
Xanomeline High Dose		Week 6	36.9	36.9	0.0
Xanomeline High Dose		Week 8	36.9	36.9	0.0
Xanomeline High Dose			36.9	36.9
Xanomeline High Dose			36.9	36.9
Placebo		Week 12	36.8	37.0	-0.2
Placebo		Week 16	36.9	37.0	-0.1
Placebo		Week 2	37.0	37.0	0.0
Placebo		Week 20	36.9	37.0	-0.1
Placebo		Week 24	36.9	37.0	-0.1
Placebo		Week 26	37.0	37.0	0.0
Placebo		Week 4	36.9	37.0	-0.1
Placebo		Week 6	37.0	37.0	0.0
Placebo		Week 8	37.0	37.0	0.0
Placebo			36.9	37.0
Xanomeline High Dose		Week 2	37.0	36.9	0.1
Xanomeline High Dose			36.9	36.9
Xanomeline Low Dose		Week 12	36.9	36.9	0.0
Xanomeline Low Dose		Week 16	36.9	36.9	0.0
Xanomeline Low Dose		Week 2	37.0	36.9	0.1
Xanomeline Low Dose		Week 4	36.9	36.9	0.0
Xanomeline Low Dose		Week 6	36.9	36.9	0.0
Xanomeline Low Dose		Week 8	36.9	36.9	0.0
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose		Week 12	37.0	36.9	0.1
Xanomeline Low Dose		Week 16	36.9	36.9	0.0
Xanomeline Low Dose		Week 2	36.9	36.9	-0.0
Xanomeline Low Dose		Week 20	37.0	36.9	0.1
Xanomeline Low Dose		Week 24	36.9	36.9	0.0
Xanomeline Low Dose		Week 26	36.9	36.9	-0.0
Xanomeline Low Dose		Week 4	36.9	36.9	-0.0
Xanomeline Low Dose		Week 6	36.7	36.9	-0.2
Xanomeline Low Dose		Week 8	36.9	36.9	0.0
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose			37.0	36.9
Placebo		Week 12	36.2	36.6	-0.4
Placebo		Week 16	37.0	36.6	0.4
Placebo		Week 2	36.6	36.6	0.0
Placebo		Week 20	37.0	36.6	0.4
Placebo		Week 24	36.2	36.6	-0.4
Placebo		Week 4	37.0	36.6	0.4
Placebo		Week 6	36.2	36.6	-0.3
Placebo		Week 8	36.4	36.6	-0.1
Placebo			36.7	36.6
Placebo			36.4	36.6
Xanomeline High Dose		Week 2	36.7	36.6	0.1
Xanomeline High Dose		Week 4	36.7	36.6	0.1
Xanomeline High Dose			36.8	36.6
Xanomeline High Dose			36.7	36.6
Placebo		Week 12	36.9	36.6	0.3
Placebo		Week 16	36.6	36.6	0.0
Placebo		Week 2	36.4	36.6	-0.1
Placebo		Week 20	36.6	36.6	0.0
Placebo		Week 24	36.6	36.6	0.0
Placebo		Week 4	36.7	36.6	0.1
Placebo		Week 6	36.8	36.6	0.2
Placebo		Week 8	36.4	36.6	-0.1
Placebo			36.7	36.6
Placebo			36.7	36.6
Xanomeline Low Dose		Week 2	36.4	35.9	0.5
Xanomeline Low Dose			36.2	35.9
Xanomeline Low Dose		Week 12	36.4	36.2	0.2
Xanomeline Low Dose		Week 16	36.3	36.2	0.1
Xanomeline Low Dose		Week 2	36.3	36.2	0.1
Xanomeline Low Dose		Week 20	37.3	36.2	1.1
Xanomeline Low Dose		Week 24	36.2	36.2	-0.0
Xanomeline Low Dose		Week 26	36.6	36.2	0.3
Xanomeline Low Dose		Week 4	36.8	36.2	0.6
Xanomeline Low Dose		Week 6	36.3	36.2	0.1
Xanomeline Low Dose		Week 8	36.2	36.2	0.0
Xanomeline Low Dose			36.4	36.2
Xanomeline Low Dose			36.1	36.2
Placebo		Week 12	36.9	36.8	0.1
Placebo		Week 16	36.4	36.8	-0.4
Placebo		Week 2	36.7	36.8	-0.1
Placebo		Week 20	35.8	36.8	-1.0
Placebo		Week 24	35.6	36.8	-1.2
Placebo		Week 26	36.6	36.8	-0.2
Placebo		Week 4	36.0	36.8	-0.8
Placebo		Week 6	36.5	36.8	-0.3
Placebo		Week 8	36.4	36.8	-0.4
Placebo			36.1	36.8
Placebo		Week 2	36.7	37.2	-0.5
Placebo		Week 4	37.0	37.2	-0.2
Placebo			36.4	37.2
Placebo			36.6	37.2
Placebo		Week 12	36.4	36.7	-0.3
Placebo		Week 16	36.2	36.7	-0.5
Placebo		Week 2	36.5	36.7	-0.2
Placebo		Week 20	36.3	36.7	-0.3
Placebo		Week 24	34.7	36.7	-2.0
Placebo		Week 26	36.3	36.7	-0.4
Placebo		Week 4	36.1	36.7	-0.6
Placebo		Week 6	36.2	36.7	-0.5
Placebo		Week 8	36.6	36.7	-0.1
Placebo			36.1	36.7
Placebo			36.0	36.7
Xanomeline High Dose		Week 12	36.4	36.6	-0.2
Xanomeline High Dose		Week 2	37.2	36.6	0.6
Xanomeline High Dose		Week 4	36.9	36.6	0.3
Xanomeline High Dose		Week 6	37.1	36.6	0.5
Xanomeline High Dose		Week 8	36.9	36.6	0.3
Xanomeline High Dose			37.1	36.6
Xanomeline High Dose			35.9	36.6
Xanomeline Low Dose		Week 2	36.1	36.2	-0.2
Xanomeline High Dose		Week 2	36.6	36.0	0.6
Xanomeline High Dose		Week 4	36.5	36.0	0.5
Xanomeline High Dose			36.4	36.0
Xanomeline High Dose			36.6	36.0
Placebo		Week 12	36.5	35.9	0.6
Placebo		Week 16	36.7	35.9	0.8
Placebo		Week 2	35.3	35.9	-0.6
Placebo		Week 20	35.4	35.9	-0.5
Placebo		Week 24	36.8	35.9	0.9
Placebo		Week 26	36.3	35.9	0.4
Placebo		Week 4	35.9	35.9	0.0
Placebo		Week 6	36.0	35.9	0.1
Placebo		Week 8	36.2	35.9	0.3
Placebo			36.4	35.9
Placebo			35.9	35.9
Xanomeline Low Dose		Week 2	35.4	36.7	-1.2
Xanomeline Low Dose		Week 4	36.2	36.7	-0.5
Xanomeline Low Dose		Week 6	36.3	36.7	-0.4
Xanomeline Low Dose			36.6	36.7
Xanomeline Low Dose			36.3	36.7
Placebo		Week 12	36.4	37.1	-0.6
Placebo		Week 16	36.7	37.1	-0.4
Placebo		Week 2	36.3	37.1	-0.8
Placebo		Week 20	36.9	37.1	-0.1
Placebo		Week 24	36.4	37.1	-0.6
Placebo		Week 26	36.4	37.1	-0.6
Placebo		Week 4	36.7	37.1	-0.4
Placebo		Week 6	36.4	37.1	-0.7
Placebo		Week 8	36.6	37.1	-0.5
Placebo			36.6	37.1
Placebo			36.4	37.1
Placebo		Week 12	36.8	36.7	0.1
Placebo		Week 16	37.2	36.7	0.5
Placebo		Week 20	37.3	36.7	0.6
Placebo		Week 24	36.4	36.7	-0.3
Placebo		Week 26	36.9	36.7	0.3
Placebo		Week 4	36.6	36.7	-0.1
Placebo		Week 6	36.3	36.7	-0.3
Placebo		Week 8	36.4	36.7	-0.2
Placebo			36.7	36.7
Placebo			36.8	36.7
Xanomeline Low Dose		Week 12	36.7	37.0	-0.3
Xanomeline Low Dose		Week 2	36.2	37.0	-0.8
Xanomeline Low Dose		Week 4	36.2	37.0	-0.8
Xanomeline Low Dose		Week 6	35.7	37.0	-1.3
Xanomeline Low Dose		Week 8	36.3	37.0	-0.7
Xanomeline Low Dose			36.5	37.0
Xanomeline Low Dose			36.1	37.0
Placebo		Week 12	37.0	36.9	0.1
Placebo		Week 16	36.2	36.9	-0.7
Placebo		Week 2	36.7	36.9	-0.2
Placebo		Week 20	37.4	36.9	0.5
Placebo		Week 24	37.3	36.9	0.4
Placebo		Week 26	37.0	36.9	0.1
Placebo		Week 4	37.2	36.9	0.3
Placebo		Week 6	37.2	36.9	0.3
Placebo		Week 8	37.1	36.9	0.2
Xanomeline High Dose		Week 12	36.3	36.4	-0.2
Xanomeline High Dose		Week 16	36.8	36.4	0.4
Xanomeline High Dose		Week 2	36.8	36.4	0.3
Xanomeline High Dose		Week 20	35.9	36.4	-0.5
Xanomeline High Dose		Week 24	36.2	36.4	-0.3
Xanomeline High Dose		Week 26	36.6	36.4	0.1
Xanomeline High Dose		Week 4	36.2	36.4	-0.3
Xanomeline High Dose		Week 6	36.3	36.4	-0.2
Xanomeline High Dose		Week 8	36.3	36.4	-0.2
Xanomeline High Dose			36.7	36.4
Xanomeline High Dose			36.1	36.4
Placebo		Week 12	36.2	36.3	-0.2
Placebo		Week 16	36.9	36.3	0.6
Placebo		Week 2	36.2	36.3	-0.2
Placebo		Week 20	36.4	36.3	0.1
Placebo		Week 24	36.6	36.3	0.2
Placebo		Week 26	36.3	36.3	0.0
Placebo		Week 4	36.1	36.3	-0.2
Placebo		Week 6	36.6	36.3	0.3
Placebo		Week 8	36.2	36.3	-0.1
Placebo			37.1	36.3
Placebo			36.2	36.3
Xanomeline High Dose		Week 12	36.3	36.5	-0.2
Xanomeline High Dose		Week 2	36.8	36.5	0.3
Xanomeline High Dose		Week 4	36.7	36.5	0.2
Xanomeline High Dose		Week 6	36.8	36.5	0.3
Xanomeline High Dose		Week 8	36.6	36.5	0.1
Xanomeline High Dose			36.9	36.5
Xanomeline High Dose			36.6	36.5
Xanomeline Low Dose		Week 12	36.6	36.6	0.0
Xanomeline Low Dose		Week 16	36.3	36.6	-0.3
Xanomeline Low Dose		Week 2	35.7	36.6	-0.8
Xanomeline Low Dose		Week 20	36.5	36.6	-0.1
Xanomeline Low Dose		Week 24	36.5	36.6	-0.1
Xanomeline Low Dose		Week 26	36.7	36.6	0.1
Xanomeline Low Dose		Week 4	36.3	36.6	-0.2
Xanomeline Low Dose		Week 6	35.8	36.6	-0.8
Xanomeline Low Dose		Week 8	36.7	36.6	0.1
Xanomeline Low Dose			36.4	36.6
Xanomeline Low Dose			36.7	36.6
Xanomeline Low Dose		Week 2	36.1	36.3	-0.2
Xanomeline Low Dose		Week 4	36.3	36.3	0.0
Xanomeline Low Dose		Week 6	37.0	36.3	0.7
Xanomeline Low Dose			36.2	36.3
Placebo		Week 12	37.1	36.2	0.9
Placebo		Week 16	36.3	36.2	0.1
Placebo		Week 2	36.6	36.2	0.4
Placebo		Week 20	35.9	36.2	-0.3
Placebo		Week 4	36.3	36.2	0.1
Placebo		Week 6	36.7	36.2	0.5
Placebo		Week 8	36.1	36.2	-0.1
Placebo			35.7	36.2
Xanomeline High Dose		Week 12	36.8	36.9	-0.1
Xanomeline High Dose		Week 16	37.2	36.9	0.2
Xanomeline High Dose		Week 2	36.7	36.9	-0.3
Xanomeline High Dose		Week 20	38.1	36.9	1.1
Xanomeline High Dose		Week 24	37.5	36.9	0.6
Xanomeline High Dose		Week 26	36.6	36.9	-0.4
Xanomeline High Dose		Week 4	36.8	36.9	-0.2
Xanomeline High Dose		Week 6	36.3	36.9	-0.6
Xanomeline High Dose		Week 8	36.7	36.9	-0.3
Xanomeline High Dose			36.4	36.9
Xanomeline High Dose			36.7	36.9
Xanomeline Low Dose		Week 2	36.5	36.7	-0.2
Xanomeline Low Dose		Week 4	36.3	36.7	-0.3
Xanomeline Low Dose			36.6	36.7
Xanomeline Low Dose			36.4	36.7
Placebo		Week 12	36.2	36.3	-0.1
Placebo		Week 16	37.3	36.3	1.0
Placebo		Week 2	36.1	36.3	-0.2
Placebo		Week 24	36.7	36.3	0.4
Placebo		Week 26	36.7	36.3	0.4
Placebo		Week 4	36.7	36.3	0.4
Placebo		Week 6	36.8	36.3	0.5
Placebo		Week 8	36.7	36.3	0.4
Placebo			36.1	36.3
Placebo			36.9	36.3
Xanomeline Low Dose		Week 2	35.9	35.4	0.5
Xanomeline Low Dose			35.6	35.4
Xanomeline Low Dose		Week 12	36.4	36.7	-0.3
Xanomeline Low Dose		Week 2	36.0	36.7	-0.7
Xanomeline Low Dose		Week 20	36.3	36.7	-0.4
Xanomeline Low Dose		Week 24	36.6	36.7	-0.1
Xanomeline Low Dose		Week 26	36.5	36.7	-0.2
Xanomeline Low Dose		Week 4	36.5	36.7	-0.2
Xanomeline Low Dose		Week 6	36.7	36.7	-0.0
Xanomeline Low Dose		Week 8	35.9	36.7	-0.8
Xanomeline High Dose		Week 12	37.0	35.9	1.1
Xanomeline High Dose		Week 16	36.2	35.9	0.3
Xanomeline High Dose		Week 2	36.0	35.9	0.1
Xanomeline High Dose		Week 20	36.1	35.9	0.1
Xanomeline High Dose		Week 26	36.8	35.9	0.8
Xanomeline High Dose		Week 4	36.1	35.9	0.2
Xanomeline High Dose		Week 6	36.3	35.9	0.3
Xanomeline High Dose		Week 8	36.6	35.9	0.7
Xanomeline High Dose			36.2	35.9
Xanomeline High Dose			36.1	35.9
Xanomeline Low Dose		Week 12	36.7	35.8	0.9
Xanomeline Low Dose		Week 2	36.2	35.8	0.4
Xanomeline Low Dose		Week 4	36.2	35.8	0.3
Xanomeline Low Dose		Week 6	36.1	35.8	0.3
Xanomeline Low Dose		Week 8	36.8	35.8	1.0
Xanomeline Low Dose			36.5	35.8
Xanomeline Low Dose			36.6	35.8
Placebo		Week 12	36.3	36.3	0.0
Placebo		Week 16	36.8	36.3	0.5
Placebo		Week 2	35.9	36.3	-0.3
Placebo		Week 20	36.2	36.3	-0.1
Placebo		Week 26	36.4	36.3	0.1
Placebo		Week 4	36.3	36.3	0.0
Placebo		Week 6	36.0	36.3	-0.3
Placebo		Week 8	36.1	36.3	-0.2
Placebo			35.9	36.3
Placebo			36.0	36.3
Xanomeline High Dose		Week 12	36.9	37.0	-0.1
Xanomeline High Dose		Week 16	36.4	37.0	-0.6
Xanomeline High Dose		Week 2	37.4	37.0	0.4
Xanomeline High Dose		Week 20	36.6	37.0	-0.4
Xanomeline High Dose		Week 24	37.1	37.0	0.1
Xanomeline High Dose		Week 26	36.6	37.0	-0.4
Xanomeline High Dose		Week 4	37.3	37.0	0.3
Xanomeline High Dose		Week 6	36.6	37.0	-0.4
Xanomeline High Dose		Week 8	36.8	37.0	-0.2
Xanomeline High Dose			36.6	37.0
Xanomeline High Dose			36.6	37.0
Xanomeline Low Dose		Week 2	36.5	36.7	-0.2
Xanomeline Low Dose		Week 4	36.6	36.7	-0.1
Xanomeline Low Dose		Week 6	36.3	36.7	-0.3
Xanomeline Low Dose			36.1	36.7
Xanomeline Low Dose			36.8	36.7
Xanomeline High Dose		Week 2	36.9	36.6	0.3
Xanomeline High Dose		Week 4	36.5	36.6	-0.1
Xanomeline High Dose		Week 6	36.7	36.6	0.1
Xanomeline High Dose			36.8	36.6
Xanomeline Low Dose		Week 12	35.3	35.5	-0.2
Xanomeline Low Dose		Week 2	36.1	35.5	0.6
Xanomeline Low Dose		Week 4	36.1	35.5	0.6
Xanomeline Low Dose		Week 6	36.0	35.5	0.5
Xanomeline Low Dose		Week 8	36.0	35.5	0.5
Xanomeline Low Dose			35.4	35.5
Xanomeline Low Dose			36.1	35.5
Xanomeline High Dose		Week 2	37.0	36.9	0.1
Xanomeline High Dose		Week 4	37.0	36.9	0.1
Xanomeline High Dose		Week 6	36.8	36.9	-0.1
Xanomeline High Dose		Week 8	36.7	36.9	-0.2
Xanomeline High Dose			37.1	36.9
Placebo		Week 12	37.3	36.9	0.4
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.3	36.9	-0.6
Placebo		Week 20	36.9	36.9	0.0
Placebo		Week 4	36.7	36.9	-0.2
Placebo		Week 6	36.6	36.9	-0.3
Placebo		Week 8	36.6	36.9	-0.3
Placebo			36.6	36.9
Placebo			36.9	36.9
Xanomeline Low Dose		Week 2	36.5	36.7	-0.2
Xanomeline Low Dose		Week 4	36.6	36.7	-0.1
Xanomeline Low Dose		Week 6	36.3	36.7	-0.4
Xanomeline Low Dose		Week 8	37.0	36.7	0.3
Xanomeline Low Dose			36.4	36.7
Xanomeline Low Dose			36.3	36.7
Placebo		Week 12	36.2	35.5	0.7
Placebo		Week 16	36.8	35.5	1.3
Placebo		Week 2	36.2	35.5	0.7
Placebo		Week 20	36.4	35.5	0.9
Placebo		Week 24	35.9	35.5	0.4
Placebo		Week 26	36.2	35.5	0.7
Placebo		Week 4	35.9	35.5	0.4
Placebo		Week 6	36.5	35.5	1.0
Placebo		Week 8	36.5	35.5	1.0
Placebo			36.8	35.5
Placebo			35.6	35.5
Placebo		Week 12	36.6	36.7	-0.1
Placebo		Week 16	35.8	36.7	-0.9
Placebo		Week 2	36.3	36.7	-0.3
Placebo		Week 4	36.7	36.7	0.0
Placebo		Week 6	36.6	36.7	-0.1
Placebo		Week 8	36.9	36.7	0.2
Placebo			36.6	36.7
Placebo			36.4	36.7
Xanomeline High Dose		Week 12	36.7	36.4	0.3
Xanomeline High Dose		Week 16	36.0	36.4	-0.4
Xanomeline High Dose		Week 2	35.7	36.4	-0.7
Xanomeline High Dose		Week 20	36.7	36.4	0.2
Xanomeline High Dose		Week 24	36.6	36.4	0.1
Xanomeline High Dose		Week 26	36.5	36.4	0.1
Xanomeline High Dose		Week 4	36.5	36.4	0.1
Xanomeline High Dose		Week 6	36.4	36.4	0.0
Xanomeline High Dose		Week 8	35.8	36.4	-0.6
Xanomeline High Dose			36.4	36.4
Xanomeline High Dose			36.1	36.4
Placebo		Week 12	36.5	36.7	-0.2
Placebo		Week 16	36.1	36.7	-0.6
Placebo		Week 2	37.1	36.7	0.4
Placebo		Week 20	36.7	36.7	-0.0
Placebo		Week 24	36.9	36.7	0.2
Placebo		Week 26	36.8	36.7	0.1
Placebo		Week 4	37.3	36.7	0.6
Placebo		Week 6	36.7	36.7	-0.0
Placebo		Week 8	36.6	36.7	-0.1
Placebo			36.6	36.7
Xanomeline Low Dose		Week 12	36.9	36.8	0.1
Xanomeline Low Dose		Week 16	37.0	36.8	0.2
Xanomeline Low Dose		Week 2	36.9	36.8	0.1
Xanomeline Low Dose		Week 20	36.2	36.8	-0.6
Xanomeline Low Dose		Week 26	36.9	36.8	0.1
Xanomeline Low Dose		Week 4	36.9	36.8	0.1
Xanomeline Low Dose		Week 6	36.9	36.8	0.1
Xanomeline Low Dose		Week 8	37.0	36.8	0.2
Xanomeline Low Dose			37.0	36.8
Xanomeline Low Dose			36.4	36.8
Placebo		Week 12	36.4	35.3	1.1
Placebo		Week 16	36.5	35.3	1.2
Placebo		Week 2	36.4	35.3	1.1
Placebo		Week 20	36.4	35.3	1.1
Placebo		Week 24	36.5	35.3	1.2
Placebo		Week 26	36.7	35.3	1.3
Placebo		Week 4	36.1	35.3	0.8
Placebo		Week 6	36.4	35.3	1.1
Placebo		Week 8	35.9	35.3	0.6
Placebo			36.2	35.3
Placebo			36.6	35.3
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline High Dose		Week 12	37.0	37.0	0.0
Xanomeline High Dose		Week 16	37.0	37.0	0.0
Xanomeline High Dose		Week 2	37.0	37.0	0.0
Xanomeline High Dose		Week 20	37.0	37.0	0.0
Xanomeline High Dose		Week 24	36.9	37.0	-0.1
Xanomeline High Dose		Week 4	36.9	37.0	-0.1
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose		Week 8	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose		Week 2	37.0	37.0	0.0
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose			36.9	37.0
Xanomeline High Dose			37.0	37.0
Placebo		Week 12	37.0	37.0	0.0
Placebo		Week 16	37.0	37.0	0.0
Placebo		Week 2	37.0	37.0	0.0
Placebo		Week 20	37.0	37.0	0.0
Placebo		Week 24	37.0	37.0	0.0
Placebo		Week 26	37.0	37.0	0.0
Placebo		Week 4	37.0	37.0	0.0
Placebo		Week 6	37.0	37.0	0.0
Placebo		Week 8	37.0	37.0	0.0
Xanomeline Low Dose		Week 2	36.9	36.9	0.0
Xanomeline Low Dose		Week 4	36.9	36.9	0.0
Xanomeline Low Dose		Week 6	37.0	36.9	0.1
Xanomeline Low Dose		Week 8	36.9	36.9	0.0
Xanomeline Low Dose			37.0	36.9
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose		Week 2	36.9	37.0	-0.1
Xanomeline Low Dose		Week 4	36.9	37.0	-0.1
Xanomeline Low Dose		Week 6	36.9	37.0	-0.1
Xanomeline Low Dose			37.0	37.0
Xanomeline Low Dose			36.9	37.0
Placebo		Week 12	37.0	37.0	0.0
Placebo		Week 16	37.0	37.0	0.0
Placebo		Week 2	37.0	37.0	0.0
Placebo		Week 20	37.0	37.0	0.0
Placebo		Week 24	37.0	37.0	0.0
Placebo		Week 26	37.0	37.0	0.0
Placebo		Week 4	37.0	37.0	0.0
Placebo		Week 6	37.0	37.0	0.0
Placebo		Week 8	36.9	37.0	-0.1
Placebo			37.0	37.0
Placebo			37.0	37.0
Xanomeline High Dose		Week 12	36.9	37.0	-0.1
Xanomeline High Dose		Week 16	36.9	37.0	-0.1
Xanomeline High Dose		Week 2	36.9	37.0	-0.1
Xanomeline High Dose		Week 4	36.9	37.0	-0.1
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose		Week 8	36.9	37.0	-0.1
Xanomeline High Dose			36.9	37.0
Placebo		Week 12	37.0	36.9	0.1
Placebo		Week 16	37.0	36.9	0.1
Placebo		Week 2	36.9	36.9	0.0
Placebo		Week 20	36.9	36.9	0.0
Placebo		Week 24	36.9	36.9	0.0
Placebo		Week 26	37.0	36.9	0.1
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	37.0	36.9	0.1
Placebo			36.9	36.9
Placebo		Week 12	37.0	36.9	0.1
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.9	36.9	0.0
Placebo		Week 20	36.9	36.9	0.0
Placebo		Week 24	37.0	36.9	0.1
Placebo		Week 26	37.0	36.9	0.1
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	36.9	36.9	0.0
Placebo			36.9	36.9
Placebo			37.0	36.9
Xanomeline High Dose		Week 2	36.9	37.0	-0.1
Xanomeline High Dose		Week 4	36.9	37.0	-0.1
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose		Week 2	36.9	37.0	-0.1
Xanomeline High Dose			36.9	37.0
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline Low Dose		Week 4	37.0	37.0	0.0
Xanomeline Low Dose		Week 12	37.0	37.0	0.0
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline Low Dose		Week 4	37.0	37.0	0.0
Xanomeline Low Dose		Week 6	36.9	37.0	-0.1
Xanomeline Low Dose		Week 8	36.9	37.0	-0.1
Xanomeline Low Dose			37.0	37.0
Xanomeline Low Dose			37.0	37.0
Placebo		Week 12	36.9	37.0	-0.1
Placebo		Week 16	36.9	37.0	-0.1
Placebo		Week 2	36.9	37.0	-0.1
Placebo		Week 20	37.0	37.0	0.0
Placebo		Week 24	37.0	37.0	0.0
Placebo		Week 26	37.0	37.0	0.0
Placebo		Week 4	36.9	37.0	-0.1
Placebo		Week 6	36.9	37.0	-0.1
Placebo		Week 8	36.9	37.0	-0.1
Placebo			36.9	37.0
Placebo			36.9	37.0
Xanomeline High Dose		Week 12	36.9	36.9	0.0
Xanomeline High Dose		Week 16	36.9	36.9	0.0
Xanomeline High Dose		Week 2	37.0	36.9	0.1
Xanomeline High Dose		Week 20	37.0	36.9	0.1
Xanomeline High Dose		Week 24	36.9	36.9	0.0
Xanomeline High Dose		Week 26	36.9	36.9	0.0
Xanomeline High Dose		Week 4	36.9	36.9	0.0
Xanomeline High Dose		Week 6	36.9	36.9	0.0
Xanomeline High Dose		Week 8	36.9	36.9	0.0
Xanomeline High Dose			36.9	36.9
Xanomeline Low Dose		Week 12	37.0	37.0	0.0
Xanomeline Low Dose		Week 16	37.0	37.0	0.0
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline Low Dose		Week 20	37.0	37.0	0.0
Xanomeline Low Dose		Week 24	37.0	37.0	0.0
Xanomeline Low Dose		Week 26	37.0	37.0	0.0
Xanomeline Low Dose		Week 4	37.0	37.0	0.0
Xanomeline Low Dose		Week 6	37.0	37.0	0.0
Xanomeline Low Dose		Week 8	37.0	37.0	0.0
Xanomeline Low Dose			37.0	37.0
Xanomeline Low Dose			37.0	37.0
Xanomeline High Dose		Week 12	37.0	37.0	0.0
Xanomeline High Dose		Week 16	37.0	37.0	0.0
Xanomeline High Dose		Week 2	37.0	37.0	0.0
Xanomeline High Dose		Week 20	37.0	37.0	0.0
Xanomeline High Dose		Week 24	37.0	37.0	0.0
Xanomeline High Dose		Week 26	37.0	37.0	0.0
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose		Week 6	36.9	37.0	-0.1
Xanomeline High Dose		Week 8	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Placebo		Week 12	37.0	37.0	0.0
Placebo		Week 16	37.0	37.0	0.0
Placebo		Week 2	37.0	37.0	0.0
Placebo		Week 4	37.0	37.0	0.0
Placebo		Week 6	37.0	37.0	0.0
Placebo		Week 8	37.0	37.0	0.0
Placebo			37.0	37.0
Placebo			37.0	37.0
Xanomeline Low Dose		Week 2	37.0	36.9	0.1
Placebo		Week 2	36.9	36.9	0.0
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.9	36.9	0.0
Placebo			36.9	36.9
Placebo			36.9	36.9
Xanomeline High Dose		Week 2	35.9	37.0	-1.1
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose		Week 8	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Xanomeline Low Dose		Week 2	36.9	36.9	0.0
Xanomeline Low Dose		Week 4	36.9	36.9	0.0
Xanomeline Low Dose		Week 6	36.9	36.9	0.0
Xanomeline Low Dose		Week 8	36.9	36.9	0.0
Xanomeline Low Dose			36.9	36.9
Xanomeline Low Dose			37.0	36.9
Placebo		Week 2	36.9	37.0	-0.1
Placebo		Week 4	36.9	37.0	-0.1
Placebo			37.0	37.0
Placebo		Week 12	36.9	36.9	0.0
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	37.0	36.9	0.1
Placebo		Week 4	37.0	36.9	0.1
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	37.0	36.9	0.1
Placebo			36.9	36.9
Placebo			36.9	36.9
Xanomeline High Dose		Week 12	37.0	37.0	0.0
Xanomeline High Dose		Week 16	37.0	37.0	0.0
Xanomeline High Dose		Week 2	37.0	37.0	0.0
Xanomeline High Dose		Week 20	37.0	37.0	0.0
Xanomeline High Dose		Week 24	37.0	37.0	0.0
Xanomeline High Dose		Week 26	37.0	37.0	0.0
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose		Week 8	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Xanomeline Low Dose		Week 12	37.0	37.0	0.0
Xanomeline Low Dose		Week 16	37.0	37.0	0.0
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline Low Dose		Week 20	37.0	37.0	0.0
Xanomeline Low Dose		Week 4	37.0	37.0	0.0
Xanomeline Low Dose		Week 6	37.0	37.0	0.0
Xanomeline Low Dose		Week 8	37.0	37.0	0.0
Xanomeline Low Dose			37.0	37.0
Xanomeline Low Dose			37.0	37.0
Placebo		Week 12	36.9	36.9	0.0
Placebo		Week 16	36.9	36.9	0.0
Placebo		Week 2	36.9	36.9	0.0
Placebo		Week 20	36.9	36.9	0.0
Placebo		Week 24	36.9	36.9	0.0
Placebo		Week 26	36.9	36.9	0.0
Placebo		Week 4	36.9	36.9	0.0
Placebo		Week 6	36.9	36.9	0.0
Placebo		Week 8	36.9	36.9	0.0
Placebo			36.9	36.9
Placebo			36.9	36.9
Xanomeline Low Dose		Week 12	37.0	37.0	0.0
Xanomeline Low Dose		Week 16	37.0	37.0	0.0
Xanomeline Low Dose		Week 2	37.0	37.0	0.0
Xanomeline Low Dose		Week 4	37.0	37.0	0.0
Xanomeline Low Dose		Week 6	37.0	37.0	0.0
Xanomeline Low Dose		Week 8	37.0	37.0	0.0
Xanomeline Low Dose			37.0	37.0
Xanomeline Low Dose			37.0	37.0
Xanomeline High Dose		Week 12	37.0	37.0	0.0
Xanomeline High Dose		Week 16	37.0	37.0	0.0
Xanomeline High Dose		Week 2	36.9	37.0	-0.1
Xanomeline High Dose		Week 20	37.0	37.0	0.0
Xanomeline High Dose		Week 24	37.0	37.0	0.0
Xanomeline High Dose		Week 26	37.0	37.0	0.0
Xanomeline High Dose		Week 4	37.0	37.0	0.0
Xanomeline High Dose		Week 6	37.0	37.0	0.0
Xanomeline High Dose		Week 8	37.0	37.0	0.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose			37.0	37.0
Xanomeline High Dose		Week 2	36.9	37.4	-0.5
Xanomeline High Dose			36.4	37.4
Placebo		Week 12	36.3	36.2	0.2
Placebo		Week 16	36.2	36.2	0.0
Placebo		Week 2	35.9	36.2	-0.2
Placebo		Week 20	35.6	36.2	-0.6
Placebo		Week 24	35.6	36.2	-0.6
Placebo		Week 26	36.3	36.2	0.2
Placebo		Week 4	36.4	36.2	0.2
Placebo		Week 6	35.5	36.2	-0.7
Placebo		Week 8	36.2	36.2	0.0
Placebo			36.1	36.2
Placebo			36.4	36.2
Xanomeline Low Dose		Week 2	35.8	36.3	-0.5
Xanomeline Low Dose		Week 4	36.2	36.3	-0.1
Xanomeline Low Dose		Week 6	35.8	36.3	-0.5
Xanomeline Low Dose		Week 8	35.9	36.3	-0.4
Xanomeline Low Dose			36.4	36.3
Xanomeline Low Dose			36.3	36.3
Xanomeline Low Dose		Week 12	36.9	36.4	0.5
Xanomeline Low Dose		Week 16	36.4	36.4	0.0
Xanomeline Low Dose		Week 2	36.1	36.4	-0.3
Xanomeline Low Dose		Week 20	36.8	36.4	0.4
Xanomeline Low Dose		Week 24	36.2	36.4	-0.2
Xanomeline Low Dose		Week 26	36.7	36.4	0.3
Xanomeline Low Dose		Week 4	36.6	36.4	0.2
Xanomeline Low Dose		Week 6	36.6	36.4	0.2
Xanomeline Low Dose		Week 8	36.1	36.4	-0.3
Xanomeline Low Dose			37.4	36.4
Xanomeline Low Dose			37.0	36.4
Xanomeline Low Dose		Week 12	37.1	36.6	0.5
Xanomeline Low Dose		Week 16	37.0	36.6	0.4
Xanomeline Low Dose		Week 2	36.9	36.6	0.3
Xanomeline Low Dose		Week 20	36.6	36.6	0.0
Xanomeline Low Dose		Week 24	36.9	36.6	0.3
Xanomeline Low Dose		Week 26	37.1	36.6	0.5
Xanomeline Low Dose		Week 4	36.7	36.6	0.1
Xanomeline Low Dose		Week 6	36.8	36.6	0.2
Xanomeline Low Dose		Week 8	36.9	36.6	0.3
Xanomeline Low Dose			36.4	36.6
Xanomeline High Dose		Week 12	36.6	36.9	-0.3
Xanomeline High Dose		Week 16	36.3	36.9	-0.6
Xanomeline High Dose		Week 2	36.9	36.9	0.0
Xanomeline High Dose		Week 20	36.6	36.9	-0.3
Xanomeline High Dose		Week 24	36.6	36.9	-0.3
Xanomeline High Dose		Week 26	36.8	36.9	-0.1
Xanomeline High Dose		Week 4	36.9	36.9	0.0
Xanomeline High Dose		Week 6	36.8	36.9	-0.1
Xanomeline High Dose		Week 8	36.5	36.9	-0.4
Xanomeline High Dose			36.6	36.9
Xanomeline High Dose			36.7	36.9
Xanomeline High Dose		Week 2	35.7	36.3	-0.7
Xanomeline High Dose		Week 4	36.6	36.3	0.2
Xanomeline High Dose			35.6	36.3
Xanomeline High Dose			36.4	36.3
Placebo		Week 12	36.7	36.2	0.5
Placebo		Week 16	36.7	36.2	0.5
Placebo		Week 2	36.0	36.2	-0.2
Placebo		Week 20	37.2	36.2	1.0
Placebo		Week 24	36.8	36.2	0.6
Placebo		Week 26	36.4	36.2	0.3
Placebo		Week 4	35.8	36.2	-0.3
Placebo		Week 6	36.7	36.2	0.5
Placebo		Week 8	36.3	36.2	0.2
Placebo			36.1	36.2
Placebo			36.3	36.2
Xanomeline High Dose		Week 12	36.9	36.6	0.3
Xanomeline High Dose		Week 16	36.1	36.6	-0.5
Xanomeline High Dose		Week 2	36.4	36.6	-0.2
Xanomeline High Dose		Week 20	36.6	36.6	-0.0
Xanomeline High Dose		Week 24	35.7	36.6	-0.9
Xanomeline High Dose		Week 26	36.4	36.6	-0.2
Xanomeline High Dose		Week 4	36.7	36.6	0.1
Xanomeline High Dose		Week 6	36.7	36.6	0.1
Xanomeline High Dose		Week 8	36.9	36.6	0.3
Xanomeline High Dose			36.4	36.6
Xanomeline High Dose			35.9	36.6
Placebo		Week 12	36.3	36.4	-0.1
Placebo		Week 16	36.7	36.4	0.3
Placebo		Week 2	35.8	36.4	-0.6
Placebo		Week 20	36.6	36.4	0.2
Placebo		Week 24	36.4	36.4	0.0
Placebo		Week 26	36.3	36.4	-0.1
Placebo		Week 4	36.9	36.4	0.5
Placebo		Week 6	36.7	36.4	0.3
Placebo		Week 8	37.0	36.4	0.6
Placebo			36.7	36.4
Placebo			36.6	36.4
Placebo		Week 12	36.7	36.3	0.3
Placebo		Week 16	37.1	36.3	0.7
Placebo		Week 2	36.9	36.3	0.6
Placebo		Week 20	36.8	36.3	0.5
Placebo		Week 24	36.9	36.3	0.6
Placebo		Week 26	37.1	36.3	0.8
Placebo		Week 4	37.0	36.3	0.7
Placebo		Week 6	36.4	36.3	0.1
Placebo		Week 8	35.9	36.3	-0.4
Placebo			36.9	36.3
Xanomeline Low Dose		Week 12	37.1	36.6	0.5
Xanomeline Low Dose		Week 2	36.9	36.6	0.3
Xanomeline Low Dose		Week 4	36.1	36.6	-0.5
Xanomeline Low Dose		Week 6	36.7	36.6	0.1
Xanomeline Low Dose		Week 8	36.6	36.6	0.0
Xanomeline Low Dose			35.9	36.6
Xanomeline Low Dose			36.9	36.6
Placebo		Week 12	37.0	36.6	0.4
Placebo		Week 16	37.0	36.6	0.4
Placebo		Week 2	36.9	36.6	0.3
Placebo		Week 20	36.6	36.6	0.0
Placebo		Week 24	37.1	36.6	0.5
Placebo		Week 26	37.1	36.6	0.5
Placebo		Week 4	37.4	36.6	0.9
Placebo		Week 6	37.2	36.6	0.6
Placebo		Week 8	36.9	36.6	0.4
Placebo			37.3	36.6
Placebo			37.5	36.6
Xanomeline Low Dose		Week 2	37.2	36.6	0.6
Xanomeline Low Dose		Week 4	36.8	36.6	0.2
Xanomeline Low Dose		Week 6	36.9	36.6	0.3
Xanomeline Low Dose		Week 8	36.9	36.6	0.3
Xanomeline Low Dose			36.8	36.6
Xanomeline Low Dose			37.7	36.6
Xanomeline Low Dose		Week 12	36.9	36.8	0.1
Xanomeline Low Dose		Week 16	36.3	36.8	-0.5
Xanomeline Low Dose		Week 2	36.5	36.8	-0.3
Xanomeline Low Dose		Week 20	36.1	36.8	-0.7
Xanomeline Low Dose		Week 24	35.7	36.8	-1.2
Xanomeline Low Dose		Week 26	35.9	36.8	-0.9
Xanomeline Low Dose		Week 4	36.1	36.8	-0.7
Xanomeline Low Dose		Week 6	36.7	36.8	-0.1
Xanomeline Low Dose		Week 8	36.4	36.8	-0.4
Xanomeline High Dose		Week 12	36.4	36.6	-0.1
Xanomeline High Dose		Week 16	36.3	36.6	-0.2
Xanomeline High Dose		Week 2	36.7	36.6	0.2
Xanomeline High Dose		Week 20	37.4	36.6	0.9
Xanomeline High Dose		Week 24	35.9	36.6	-0.6
Xanomeline High Dose		Week 26	36.8	36.6	0.3
Xanomeline High Dose		Week 4	36.6	36.6	0.0
Xanomeline High Dose		Week 6	36.9	36.6	0.3
Xanomeline High Dose		Week 8	36.4	36.6	-0.1
Xanomeline High Dose			36.8	36.6
Placebo		Week 12	36.7	36.7	0.0
Placebo		Week 16	36.9	36.7	0.3
Placebo		Week 2	37.0	36.7	0.3
Placebo		Week 20	36.8	36.7	0.2
Placebo		Week 24	36.8	36.7	0.2
Placebo		Week 26	37.0	36.7	0.3
Placebo		Week 4	36.8	36.7	0.1
Placebo		Week 6	36.6	36.7	-0.1
Placebo		Week 8	36.5	36.7	-0.2
Placebo			36.8	36.7
Placebo			36.8	36.7
Xanomeline Low Dose		Week 12	36.4	36.5	-0.1
Xanomeline Low Dose		Week 16	36.9	36.5	0.4
Xanomeline Low Dose		Week 2	36.3	36.5	-0.2
Xanomeline Low Dose		Week 20	36.4	36.5	-0.1
Xanomeline Low Dose		Week 24	36.3	36.5	-0.2
Xanomeline Low Dose		Week 26	36.7	36.5	0.2
Xanomeline Low Dose		Week 4	36.6	36.5	0.1
Xanomeline Low Dose		Week 6	36.3	36.5	-0.2
Xanomeline Low Dose		Week 8	36.3	36.5	-0.2
Xanomeline Low Dose			36.8	36.5
Xanomeline Low Dose			36.3	36.5
Xanomeline Low Dose		Week 2	36.4	36.1	0.3
Xanomeline Low Dose		Week 4	36.7	36.1	0.6
Xanomeline Low Dose		Week 6	36.2	36.1	0.1
Xanomeline Low Dose		Week 8	37.1	36.1	1.0
Xanomeline Low Dose			36.6	36.1
Xanomeline Low Dose			36.6	36.1
Placebo		Week 2	36.4	36.4	0.0
Placebo		Week 4	36.1	36.4	-0.3
Placebo			36.3	36.4
Placebo			36.3	36.4
Placebo		Week 12	36.6	36.4	0.2
Placebo		Week 16	36.4	36.4	0.0
Placebo		Week 2	36.1	36.4	-0.3
Placebo		Week 20	36.4	36.4	0.0
Placebo		Week 24	35.8	36.4	-0.6
Placebo		Week 4	36.4	36.4	0.0
Placebo		Week 6	36.3	36.4	-0.1
Placebo		Week 8	36.9	36.4	0.5
Placebo			36.8	36.4
Placebo			36.3	36.4
Xanomeline High Dose		Week 2	36.7	36.4	0.2
Xanomeline High Dose			36.4	36.4
Xanomeline High Dose		Week 2	36.3	36.1	0.2
Xanomeline High Dose		Week 4	36.4	36.1	0.4
Xanomeline High Dose		Week 6	36.4	36.1	0.4
Xanomeline High Dose		Week 8	36.6	36.1	0.5
Xanomeline High Dose			36.0	36.1
Xanomeline High Dose			36.1	36.1
Placebo		Week 12	36.5	36.7	-0.2
Placebo		Week 16	36.9	36.7	0.3
Placebo		Week 2	36.5	36.7	-0.2
Placebo		Week 20	36.3	36.7	-0.4
Placebo		Week 24	36.3	36.7	-0.3
Placebo		Week 4	36.4	36.7	-0.2
Placebo		Week 6	36.6	36.7	-0.1
Placebo		Week 8	36.7	36.7	0.0
Placebo			36.7	36.7
Placebo			36.9	36.7
Placebo		Week 12	36.8	36.7	0.1
Placebo		Week 16	36.2	36.7	-0.5
Placebo		Week 2	36.9	36.7	0.2
Placebo		Week 20	36.1	36.7	-0.6
Placebo		Week 24	36.8	36.7	0.1
Placebo		Week 26	36.6	36.7	-0.2
Placebo		Week 4	37.6	36.7	0.8
Placebo		Week 6	37.1	36.7	0.3
Placebo		Week 8	36.8	36.7	0.1
Placebo			36.8	36.7
Placebo			36.7	36.7
Placebo		Week 12	36.2	36.3	-0.1
Placebo		Week 16	36.2	36.3	-0.1
Placebo		Week 2	35.7	36.3	-0.6
Placebo		Week 20	36.6	36.3	0.3
Placebo		Week 24	36.6	36.3	0.3
Placebo		Week 26	36.6	36.3	0.3
Placebo		Week 4	36.1	36.3	-0.2
Placebo		Week 6	35.9	36.3	-0.3
Placebo		Week 8	36.2	36.3	-0.1
Placebo			37.1	36.3
Placebo			35.9	36.3
Placebo		Week 12	36.9	36.8	0.2
Placebo		Week 16	35.9	36.8	-0.9
Placebo		Week 2	36.9	36.8	0.1
Placebo		Week 20	36.2	36.8	-0.6
Placebo		Week 24	36.0	36.8	-0.8
Placebo		Week 26	36.7	36.8	-0.1
Placebo		Week 4	36.7	36.8	-0.1
Placebo		Week 6	36.2	36.8	-0.6
Placebo		Week 8	36.3	36.8	-0.5
Placebo			36.8	36.8
Placebo			36.8	36.8
Xanomeline Low Dose		Week 12	36.3	36.1	0.2
Xanomeline Low Dose		Week 2	35.9	36.1	-0.2
Xanomeline Low Dose		Week 4	36.7	36.1	0.6
Xanomeline Low Dose		Week 6	36.0	36.1	-0.1
Xanomeline Low Dose		Week 8	36.1	36.1	-0.0
Xanomeline Low Dose			36.4	36.1
Xanomeline Low Dose			36.6	36.1
Xanomeline High Dose		Week 2	36.7	36.7	0.0
Xanomeline High Dose		Week 4	36.2	36.7	-0.5
Xanomeline High Dose		Week 6	35.6	36.7	-1.1
Xanomeline High Dose		Week 8	36.2	36.7	-0.5
Xanomeline High Dose			36.8	36.7
Xanomeline High Dose			36.3	36.7
Xanomeline Low Dose		Week 2	36.5	36.6	-0.1
Xanomeline Low Dose		Week 4	36.1	36.6	-0.5
Xanomeline Low Dose			36.3	36.6
Xanomeline Low Dose			35.9	36.6
Xanomeline Low Dose		Week 12	36.3	35.8	0.5
Xanomeline Low Dose		Week 16	36.2	35.8	0.3
Xanomeline Low Dose		Week 2	36.7	35.8	0.8
Xanomeline Low Dose		Week 20	36.3	35.8	0.5
Xanomeline Low Dose		Week 24	36.7	35.8	0.9
Xanomeline Low Dose		Week 26	36.4	35.8	0.6
Xanomeline Low Dose		Week 4	36.2	35.8	0.4
Xanomeline Low Dose		Week 6	36.2	35.8	0.4
Xanomeline Low Dose		Week 8	36.4	35.8	0.6
Xanomeline Low Dose			36.1	35.8
Xanomeline Low Dose			36.2	35.8
Placebo		Week 12	36.8	36.6	0.2
Placebo		Week 16	36.6	36.6	0.0
Placebo		Week 2	36.9	36.6	0.3
Placebo		Week 20	36.2	36.6	-0.3
Placebo		Week 24	36.4	36.6	-0.1
Placebo		Week 26	36.4	36.6	-0.1
Placebo		Week 4	36.4	36.6	-0.2
Placebo		Week 6	36.9	36.6	0.4
Placebo		Week 8	36.2	36.6	-0.3
Placebo			36.2	36.6
Placebo			36.2	36.6
Xanomeline Low Dose		Week 12	35.7	36.6	-0.9
Xanomeline Low Dose		Week 2	35.9	36.6	-0.7
Xanomeline Low Dose		Week 4	35.8	36.6	-0.8
Xanomeline Low Dose		Week 6	36.5	36.6	-0.1
Xanomeline Low Dose		Week 8	36.2	36.6	-0.4
Xanomeline Low Dose			35.7	36.6
Xanomeline Low Dose			36.0	36.6
Xanomeline Low Dose		Week 12	35.7	36.1	-0.3
Xanomeline Low Dose		Week 16	36.3	36.1	0.2
Xanomeline Low Dose		Week 2	36.5	36.1	0.4
Xanomeline Low Dose		Week 20	36.3	36.1	0.2
Xanomeline Low Dose		Week 24	36.2	36.1	0.1
Xanomeline Low Dose		Week 4	35.8	36.1	-0.2
Xanomeline Low Dose		Week 6	35.8	36.1	-0.3
Xanomeline Low Dose		Week 8	36.1	36.1	0.0
Xanomeline Low Dose			36.3	36.1
Xanomeline Low Dose			35.7	36.1
Placebo		Week 12	36.6	36.6	0.0
Placebo		Week 16	36.4	36.6	-0.1
Placebo		Week 2	36.1	36.6	-0.5
Placebo		Week 20	36.5	36.6	-0.1
Placebo		Week 26	36.9	36.6	0.3
Placebo		Week 4	36.2	36.6	-0.3
Placebo		Week 6	36.6	36.6	0.0
Placebo		Week 8	36.3	36.6	-0.3
Placebo			35.8	36.6
Placebo			36.2	36.6
Xanomeline Low Dose		Week 12	36.3	36.2	0.1
Xanomeline Low Dose		Week 16	36.2	36.2	0.0
Xanomeline Low Dose		Week 2	35.6	36.2	-0.6
Xanomeline Low Dose		Week 20	36.2	36.2	0.0
Xanomeline Low Dose		Week 24	36.8	36.2	0.6
Xanomeline Low Dose		Week 4	35.0	36.2	-1.2
Xanomeline Low Dose		Week 6	35.2	36.2	-1.0
Xanomeline Low Dose		Week 8	36.0	36.2	-0.2
Xanomeline Low Dose			35.6	36.2
Xanomeline Low Dose			35.2	36.2
Placebo		Week 12	36.5	36.6	-0.1
Placebo		Week 16	36.2	36.6	-0.4
Placebo		Week 2	36.3	36.6	-0.3
Placebo		Week 20	37.1	36.6	0.5
Placebo		Week 24	36.8	36.6	0.2
Placebo		Week 26	37.2	36.6	0.6
Placebo		Week 4	36.4	36.6	-0.2
Placebo		Week 6	36.9	36.6	0.3
Placebo		Week 8	36.6	36.6	0.0
Xanomeline High Dose		Week 12	35.6	36.2	-0.6
Xanomeline High Dose		Week 16	36.0	36.2	-0.2
Xanomeline High Dose		Week 2	36.1	36.2	-0.1
Xanomeline High Dose		Week 4	36.7	36.2	0.5
Xanomeline High Dose		Week 6	35.9	36.2	-0.3
Xanomeline High Dose		Week 8	35.6	36.2	-0.6
Xanomeline High Dose			36.1	36.2
Xanomeline High Dose			36.4	36.2
Xanomeline High Dose		Week 2	36.2	35.9	0.3
Xanomeline High Dose		Week 4	36.6	35.9	0.7
Xanomeline High Dose			36.5	35.9
Xanomeline High Dose			35.7	35.9
Xanomeline Low Dose		Week 2	36.4	36.4	0.0
Xanomeline Low Dose		Week 4	36.6	36.4	0.2
Xanomeline Low Dose		Week 6	36.3	36.4	-0.2
Xanomeline Low Dose		Week 8	36.4	36.4	-0.0
Placebo		Week 2	36.4	36.9	-0.5
Placebo		Week 4	36.3	36.9	-0.7
Placebo		Week 6	36.2	36.9	-0.7
Placebo			36.7	36.9
Placebo			36.6	36.9
Xanomeline Low Dose		Week 12	38.1	36.2	1.8
Xanomeline Low Dose		Week 16	37.3	36.2	1.1
Xanomeline Low Dose		Week 2	37.2	36.2	1.0
Xanomeline Low Dose		Week 4	36.6	36.2	0.4
Xanomeline Low Dose		Week 6	36.7	36.2	0.5
Xanomeline Low Dose		Week 8	36.6	36.2	0.4
Xanomeline High Dose		Week 12	36.5	36.8	-0.3
Xanomeline High Dose		Week 16	36.7	36.8	-0.2
Xanomeline High Dose		Week 2	36.2	36.8	-0.6
Xanomeline High Dose		Week 20	37.0	36.8	0.2
Xanomeline High Dose		Week 24	36.8	36.8	-0.0
Xanomeline High Dose		Week 26	37.2	36.8	0.4
Xanomeline High Dose		Week 4	36.7	36.8	-0.1
Xanomeline High Dose		Week 6	36.2	36.8	-0.7
Xanomeline High Dose		Week 8	36.5	36.8	-0.3
Xanomeline High Dose		Week 2	35.7	35.6	0.1
Xanomeline High Dose		Week 4	36.4	35.6	0.8
Xanomeline High Dose		Week 6	35.8	35.6	0.2
Xanomeline High Dose		Week 8	35.9	35.6	0.3
Xanomeline High Dose			35.4	35.6
Xanomeline High Dose			35.9	35.6
Xanomeline High Dose		Week 12	36.0	36.2	-0.2
Xanomeline High Dose		Week 16	36.6	36.2	0.4
Xanomeline High Dose		Week 2	36.1	36.2	-0.1
Xanomeline High Dose		Week 20	36.6	36.2	0.3
Xanomeline High Dose		Week 24	37.4	36.2	1.2
Xanomeline High Dose		Week 26	36.9	36.2	0.7
Xanomeline High Dose		Week 4	36.4	36.2	0.2
Xanomeline High Dose		Week 6	36.7	36.2	0.5
Xanomeline High Dose		Week 8	36.3	36.2	0.1
Xanomeline High Dose			36.4	36.2
Placebo		Week 12	35.8	36.2	-0.4
Placebo		Week 16	36.6	36.2	0.4
Placebo		Week 2	36.3	36.2	0.1
Placebo		Week 24	36.6	36.2	0.3
Placebo		Week 26	36.2	36.2	-0.0
Placebo		Week 4	34.3	36.2	-1.9
Placebo		Week 6	36.1	36.2	-0.1
Placebo		Week 8	36.7	36.2	0.5
Placebo			36.9	36.2
Placebo			35.0	36.2
Xanomeline High Dose		Week 12	35.9	36.3	-0.4
Xanomeline High Dose		Week 16	36.3	36.3	0.0
Xanomeline High Dose		Week 2	36.8	36.3	0.5
Xanomeline High Dose		Week 20	36.2	36.3	-0.1
Xanomeline High Dose		Week 24	36.2	36.3	-0.1
Xanomeline High Dose		Week 26	36.6	36.3	0.3
Xanomeline High Dose		Week 4	36.1	36.3	-0.3
Xanomeline High Dose		Week 6	35.9	36.3	-0.4
Xanomeline High Dose		Week 8	35.7	36.3	-0.7
Xanomeline High Dose			36.7	36.3
Xanomeline High Dose			35.9	36.3
Xanomeline Low Dose		Week 12	37.0	37.1	-0.1
Xanomeline Low Dose		Week 16	36.4	37.1	-0.7
Xanomeline Low Dose		Week 2	37.1	37.1	0.0
Xanomeline Low Dose		Week 20	36.4	37.1	-0.7
Xanomeline Low Dose		Week 24	37.1	37.1	0.0
Xanomeline Low Dose		Week 26	36.6	37.1	-0.5
Xanomeline Low Dose		Week 4	37.0	37.1	-0.1
Xanomeline Low Dose		Week 6	37.3	37.1	0.2
Xanomeline Low Dose		Week 8	36.8	37.1	-0.3
Xanomeline Low Dose			37.2	37.1
Xanomeline Low Dose			37.0	37.1
Xanomeline High Dose		Week 12	36.6	36.7	-0.1
Xanomeline High Dose		Week 16	36.2	36.7	-0.5
Xanomeline High Dose		Week 2	36.8	36.7	0.2
Xanomeline High Dose		Week 20	37.1	36.7	0.4
Xanomeline High Dose		Week 24	36.6	36.7	-0.1
Xanomeline High Dose		Week 26	36.6	36.7	-0.1
Xanomeline High Dose		Week 4	37.0	36.7	0.3
Xanomeline High Dose		Week 6	37.1	36.7	0.4
Xanomeline High Dose		Week 8	37.1	36.7	0.4
Xanomeline High Dose			37.1	36.7
Xanomeline High Dose			36.6	36.7
Xanomeline High Dose		Week 12	36.9	36.2	0.7
Xanomeline High Dose		Week 16	36.4	36.2	0.2
Xanomeline High Dose		Week 2	36.7	36.2	0.5
Xanomeline High Dose		Week 20	36.6	36.2	0.3
Xanomeline High Dose		Week 24	37.0	36.2	0.8
Xanomeline High Dose		Week 26	37.1	36.2	0.9
Xanomeline High Dose		Week 4	36.9	36.2	0.7
Xanomeline High Dose		Week 6	36.3	36.2	0.1
Xanomeline High Dose		Week 8	36.7	36.2	0.5
Xanomeline High Dose			36.8	36.2
Placebo		Week 2	37.1	36.7	0.4
Placebo		Week 4	37.1	36.7	0.4
Placebo		Week 6	36.7	36.7	0.0
Placebo		Week 8	37.4	36.7	0.8
Placebo			37.1	36.7
Placebo			37.0	36.7
Placebo		Week 2	36.4	37.1	-0.7
Placebo		Week 4	37.2	37.1	0.1
Placebo		Week 6	37.1	37.1	0.0
Placebo		Week 8	37.2	37.1	0.1
Placebo			36.6	37.1
Placebo			37.2	37.1
Xanomeline High Dose		Week 12	36.2	36.0	0.2
Xanomeline High Dose		Week 16	37.1	36.0	1.1
Xanomeline High Dose		Week 2	36.2	36.0	0.2
Xanomeline High Dose		Week 20	36.9	36.0	0.9
Xanomeline High Dose		Week 4	36.7	36.0	0.7
Xanomeline High Dose		Week 6	36.6	36.0	0.6
Xanomeline High Dose		Week 8	36.2	36.0	0.2
Xanomeline Low Dose		Week 12	36.9	36.8	0.1
Xanomeline Low Dose		Week 16	36.0	36.8	-0.8
Xanomeline Low Dose		Week 2	37.7	36.8	0.9
Xanomeline Low Dose		Week 20	36.8	36.8	0.0
Xanomeline Low Dose		Week 24	36.8	36.8	0.0
Xanomeline Low Dose		Week 4	37.1	36.8	0.3
Xanomeline Low Dose		Week 6	37.1	36.8	0.3
Xanomeline Low Dose		Week 8	37.4	36.8	0.7
Xanomeline Low Dose			37.0	36.8
Xanomeline Low Dose			37.0	36.8
Xanomeline Low Dose		Week 2	36.2	36.4	-0.2
Xanomeline Low Dose		Week 4	36.3	36.4	-0.1
Xanomeline Low Dose			35.9	36.4
Xanomeline Low Dose			36.2	36.4
Xanomeline High Dose		Week 12	36.0	35.6	0.4
Xanomeline High Dose		Week 16	35.6	35.6	-0.0
Xanomeline High Dose		Week 2	35.4	35.6	-0.2
Xanomeline High Dose		Week 20	35.1	35.6	-0.5
Xanomeline High Dose		Week 4	36.1	35.6	0.5
Xanomeline High Dose		Week 6	36.1	35.6	0.5
Xanomeline High Dose		Week 8	36.3	35.6	0.7
Xanomeline High Dose			35.9	35.6
Xanomeline High Dose			35.4	35.6
Placebo		Week 12	35.0	35.5	-0.5
Placebo		Week 16	36.2	35.5	0.7
Placebo		Week 2	35.3	35.5	-0.2
Placebo		Week 20	35.3	35.5	-0.2
Placebo		Week 24	36.2	35.5	0.7
Placebo		Week 26	35.2	35.5	-0.3
Placebo		Week 4	35.7	35.5	0.2
Placebo		Week 6	35.9	35.5	0.4
Placebo		Week 8	35.9	35.5	0.4
Placebo			35.6	35.5
Placebo			35.7	35.5
Placebo		Week 12	35.7	35.8	-0.1
Placebo		Week 16	36.5	35.8	0.7
Placebo		Week 2	35.9	35.8	0.1
Placebo		Week 20	35.6	35.8	-0.2
Placebo		Week 24	35.8	35.8	0.0
Placebo		Week 4	35.8	35.8	0.0
Placebo		Week 6	35.3	35.8	-0.5
Placebo		Week 8	36.8	35.8	1.0
Placebo			36.3	35.8
Xanomeline Low Dose		Week 2	36.0	35.5	0.5
Xanomeline Low Dose			35.1	35.5
Placebo		Week 12	35.9	35.8	0.1
Placebo		Week 2	36.4	35.8	0.7
Placebo		Week 4	35.5	35.8	-0.3
Placebo		Week 6	36.7	35.8	0.9
Placebo		Week 8	35.7	35.8	-0.1
Placebo			35.8	35.8
Placebo			35.4	35.8
Xanomeline Low Dose		Week 12	36.5	35.9	0.6
Xanomeline Low Dose		Week 16	35.9	35.9	0.0
Xanomeline Low Dose		Week 2	35.6	35.9	-0.4
Xanomeline Low Dose		Week 4	35.8	35.9	-0.2
Xanomeline Low Dose		Week 6	36.2	35.9	0.2
Xanomeline Low Dose		Week 8	35.8	35.9	-0.2
Xanomeline Low Dose			36.8	35.9
Xanomeline Low Dose			37.5	35.9
Xanomeline Low Dose		Week 12	36.1	35.7	0.4
Xanomeline Low Dose		Week 16	36.2	35.7	0.5
Xanomeline Low Dose		Week 2	35.7	35.7	0.0
Xanomeline Low Dose		Week 20	35.4	35.7	-0.3
Xanomeline Low Dose		Week 24	36.2	35.7	0.5
Xanomeline Low Dose		Week 26	35.3	35.7	-0.4
Xanomeline Low Dose		Week 4	35.7	35.7	-0.0
Xanomeline Low Dose		Week 6	35.7	35.7	-0.0
Xanomeline Low Dose		Week 8	35.8	35.7	0.1
Xanomeline Low Dose			35.4	35.7
Xanomeline Low Dose			36.8	35.7
Xanomeline High Dose		Week 2	36.0	35.6	0.4
Xanomeline High Dose		Week 4	35.3	35.6	-0.3
Xanomeline High Dose		Week 6	35.7	35.6	0.1
Xanomeline High Dose		Week 8	36.1	35.6	0.5
Xanomeline High Dose			36.4	35.6
Xanomeline High Dose			36.7	35.6
Placebo		Week 12	36.1	36.4	-0.3
Placebo		Week 16	36.1	36.4	-0.3
Placebo		Week 2	35.8	36.4	-0.6
Placebo		Week 20	37.3	36.4	0.9
Placebo		Week 24	37.6	36.4	1.2
Placebo		Week 26	36.2	36.4	-0.2
Placebo		Week 4	36.6	36.4	0.2
Placebo		Week 6	36.7	36.4	0.3
Placebo		Week 8	35.8	36.4	-0.6
Placebo			36.1	36.4
Placebo			37.8	36.4
Xanomeline High Dose		Week 2	36.2	36.4	-0.3
Xanomeline High Dose		Week 4	36.2	36.4	-0.3
Xanomeline High Dose		Week 6	35.7	36.4	-0.7
Xanomeline High Dose		Week 8	35.9	36.4	-0.5
Xanomeline High Dose			35.8	36.4
Xanomeline High Dose		Week 2	35.9	36.0	-0.1
Xanomeline High Dose		Week 4	36.3	36.0	0.3
Xanomeline High Dose		Week 6	36.2	36.0	0.2
Xanomeline High Dose			36.6	36.0
Xanomeline High Dose			35.9	36.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10

Listing 16.2.8.1

Listing of Vital Signs by Parameter

Safety Population — On-Treatment Records

WEIGHT

Treatment	Subject ID	Visit	Value	Baseline	Change from Baseline
Placebo		Week 12	53.1	54.4	-1.4
Placebo		Week 16	53.1	54.4	-1.4
Placebo		Week 2	53.1	54.4	-1.4
Placebo		Week 20	53.1	54.4	-1.4
Placebo		Week 24	53.1	54.4	-1.4
Placebo		Week 26	53.5	54.4	-0.9
Placebo		Week 4	54.0	54.4	-0.5
Placebo		Week 6	53.1	54.4	-1.4
Placebo		Week 8	53.1	54.4	-1.4
Placebo		Week 2	80.7	80.3	0.4
Xanomeline High Dose		Week 12	98.9	99.3	-0.5
Xanomeline High Dose		Week 16	99.8	99.3	0.5
Xanomeline High Dose		Week 2	99.3	99.3	0.0
Xanomeline High Dose		Week 20	99.8	99.3	0.5
Xanomeline High Dose		Week 24	99.3	99.3	0.0
Xanomeline High Dose		Week 26	99.8	99.3	0.5
Xanomeline High Dose		Week 4	98.9	99.3	-0.5
Xanomeline High Dose		Week 6	98.4	99.3	-0.9
Xanomeline High Dose		Week 8	99.3	99.3	0.0
Xanomeline High Dose		Week 12	63.0	62.6	0.4
Xanomeline High Dose		Week 16	64.4	62.6	1.8
Xanomeline High Dose		Week 2	62.6	62.6	0.0
Xanomeline High Dose		Week 20	64.9	62.6	2.3
Xanomeline High Dose		Week 24	65.3	62.6	2.7
Xanomeline High Dose		Week 26	64.0	62.6	1.4
Xanomeline High Dose		Week 4	64.0	62.6	1.4
Xanomeline High Dose		Week 6	64.0	62.6	1.4
Xanomeline High Dose		Week 8	63.0	62.6	0.4
Placebo		Week 2	67.6	67.1	0.5
Xanomeline Low Dose		Week 12	79.8	78.0	1.8
Xanomeline Low Dose		Week 16	79.4	78.0	1.4
Xanomeline Low Dose		Week 2	79.4	78.0	1.4
Xanomeline Low Dose		Week 20	79.8	78.0	1.8
Xanomeline Low Dose		Week 24	80.3	78.0	2.3
Xanomeline Low Dose		Week 26	78.5	78.0	0.5
Xanomeline Low Dose		Week 4	79.4	78.0	1.4
Xanomeline Low Dose		Week 6	79.4	78.0	1.4
Xanomeline Low Dose		Week 8	78.5	78.0	0.5
Xanomeline Low Dose		Week 2	78.9	78.9	0.0
Xanomeline Low Dose		Week 4	78.5	78.9	-0.5
Xanomeline Low Dose		Week 6	78.5	78.9	-0.5
Xanomeline Low Dose		Week 8	78.5	78.9	-0.5
Placebo		Week 12	73.5	71.2	2.3
Placebo		Week 16	73.0	71.2	1.8
Placebo		Week 2	71.2	71.2	0.0
Placebo		Week 20	71.7	71.2	0.5
Placebo		Week 24	71.2	71.2	0.0
Placebo		Week 26	73.0	71.2	1.8
Placebo		Week 4	71.2	71.2	0.0
Placebo		Week 6	71.2	71.2	0.0
Placebo		Week 8	72.6	71.2	1.4
Placebo		Week 12	78.5	79.4	-0.9
Placebo		Week 16	78.5	79.4	-0.9
Placebo		Week 2	79.4	79.4	0.0
Placebo		Week 20	78.9	79.4	-0.4
Placebo		Week 24	77.1	79.4	-2.3
Placebo		Week 26	77.6	79.4	-1.8
Placebo		Week 4	78.0	79.4	-1.4
Placebo		Week 6	78.0	79.4	-1.4
Placebo		Week 8	79.8	79.4	0.5
Xanomeline High Dose		Week 12	76.2	74.4	1.8
Xanomeline High Dose		Week 16	75.3	74.4	0.9
Xanomeline High Dose		Week 2	73.9	74.4	-0.5
Xanomeline High Dose		Week 20	74.4	74.4	0.0
Xanomeline High Dose		Week 24	72.6	74.4	-1.8
Xanomeline High Dose		Week 4	74.4	74.4	0.0
Xanomeline High Dose		Week 6	74.8	74.4	0.5
Xanomeline High Dose		Week 8	75.3	74.4	0.9
Xanomeline High Dose		Week 2	54.4	54.0	0.5
Xanomeline High Dose		Week 4	54.4	54.0	0.5
Xanomeline High Dose		Week 12	88.5	87.1	1.4
Xanomeline High Dose		Week 16	88.0	87.1	0.9
Xanomeline High Dose		Week 2	87.5	87.1	0.5
Xanomeline High Dose		Week 20	90.3	87.1	3.2
Xanomeline High Dose		Week 24	90.3	87.1	3.2
Xanomeline High Dose		Week 26	90.7	87.1	3.6
Xanomeline High Dose		Week 4	88.9	87.1	1.8
Xanomeline High Dose		Week 6	87.5	87.1	0.5
Xanomeline High Dose		Week 8	88.5	87.1	1.4
Placebo		Week 12	57.1	58.1	-0.9
Placebo		Week 16	56.2	58.1	-1.8
Placebo		Week 2	57.1	58.1	-0.9
Placebo		Week 20	57.1	58.1	-0.9
Placebo		Week 24	56.2	58.1	-1.8
Placebo		Week 4	56.7	58.1	-1.4
Placebo		Week 6	57.6	58.1	-0.5
Placebo		Week 8	58.1	58.1	0.0
Xanomeline High Dose		Week 2	90.3	89.8	0.5
Xanomeline High Dose		Week 4	89.4	89.8	-0.5
Xanomeline Low Dose		Week 2	101.6	101.2	0.5
Xanomeline Low Dose		Week 4	102.1	101.2	0.9
Xanomeline Low Dose		Week 12	63.5	63.5	0.0
Xanomeline Low Dose		Week 16	63.5	63.5	0.0
Xanomeline Low Dose		Week 2	64.0	63.5	0.5
Xanomeline Low Dose		Week 20	62.6	63.5	-0.9
Xanomeline Low Dose		Week 24	62.6	63.5	-0.9
Xanomeline Low Dose		Week 26	62.1	63.5	-1.4
Xanomeline Low Dose		Week 4	64.0	63.5	0.5
Xanomeline Low Dose		Week 6	64.9	63.5	1.4
Xanomeline Low Dose		Week 8	62.1	63.5	-1.4
Placebo		Week 12	67.6	66.2	1.4
Placebo		Week 16	66.2	66.2	0.0
Placebo		Week 2	66.7	66.2	0.5
Placebo		Week 20	64.9	66.2	-1.4
Placebo		Week 24	64.9	66.2	-1.4
Placebo		Week 26	64.0	66.2	-2.3
Placebo		Week 4	65.8	66.2	-0.5
Placebo		Week 6	67.1	66.2	0.9
Placebo		Week 8	66.2	66.2	0.0
Xanomeline Low Dose		Week 2	45.4	45.4	0.0
Xanomeline Low Dose		Week 4	45.8	45.4	0.5
Xanomeline Low Dose		Week 6	45.4	45.4	0.0
Xanomeline Low Dose		Week 8	43.1	45.4	-2.3
Placebo		Week 12	76.7	77.1	-0.5
Placebo		Week 16	76.7	77.1	-0.5
Placebo		Week 2	77.1	77.1	0.0
Placebo		Week 20	77.1	77.1	0.0
Placebo		Week 24	76.7	77.1	-0.5
Placebo		Week 26	77.6	77.1	0.5
Placebo		Week 4	77.1	77.1	0.0
Placebo		Week 6	77.1	77.1	0.0
Placebo		Week 8	77.1	77.1	0.0
Xanomeline High Dose		Week 12	94.8	95.9	-1.1
Xanomeline High Dose		Week 16	95.7	95.9	-0.2
Xanomeline High Dose		Week 2	95.7	95.9	-0.2
Xanomeline High Dose		Week 20	96.2	95.9	0.2
Xanomeline High Dose		Week 24	97.1	95.9	1.1
Xanomeline High Dose		Week 4	95.3	95.9	-0.7
Xanomeline High Dose		Week 6	96.6	95.9	0.7
Xanomeline High Dose		Week 8	94.3	95.9	-1.6
Xanomeline High Dose		Week 12	70.3	69.0	1.4
Xanomeline High Dose		Week 2	69.0	69.0	0.0
Xanomeline High Dose		Week 4	69.8	69.0	0.9
Xanomeline High Dose		Week 6	71.2	69.0	2.3
Xanomeline High Dose		Week 8	70.8	69.0	1.8
Xanomeline High Dose		Week 12	56.2	56.2	0.0
Xanomeline High Dose		Week 16	55.3	56.2	-0.9
Xanomeline High Dose		Week 2	57.1	56.2	0.9
Xanomeline High Dose		Week 20	54.9	56.2	-1.4
Xanomeline High Dose		Week 24	55.8	56.2	-0.5
Xanomeline High Dose		Week 26	55.8	56.2	-0.5
Xanomeline High Dose		Week 4	57.1	56.2	0.9
Xanomeline High Dose		Week 6	56.2	56.2	0.0
Xanomeline High Dose		Week 8	55.8	56.2	-0.5
Xanomeline Low Dose		Week 12	80.3	78.5	1.8
Xanomeline Low Dose		Week 2	78.5	78.5	0.0
Xanomeline Low Dose		Week 4	78.5	78.5	0.0
Xanomeline Low Dose		Week 6	78.9	78.5	0.5
Xanomeline Low Dose		Week 8	79.8	78.5	1.4
Xanomeline High Dose		Week 12	82.1	82.1	0.0
Xanomeline High Dose		Week 2	81.2	82.1	-0.9
Xanomeline High Dose		Week 4	82.6	82.1	0.5
Xanomeline High Dose		Week 6	80.7	82.1	-1.4
Xanomeline High Dose		Week 8	82.1	82.1	0.0
Xanomeline Low Dose		Week 12	64.9	66.7	-1.8
Xanomeline Low Dose		Week 16	66.7	66.7	0.0
Xanomeline Low Dose		Week 2	66.7	66.7	0.0
Xanomeline Low Dose		Week 20	67.1	66.7	0.4
Xanomeline Low Dose		Week 24	67.6	66.7	0.9
Xanomeline Low Dose		Week 26	68.0	66.7	1.4
Xanomeline Low Dose		Week 4	68.0	66.7	1.4
Xanomeline Low Dose		Week 6	67.6	66.7	0.9
Xanomeline Low Dose		Week 8	67.6	66.7	0.9
Xanomeline Low Dose		Week 12	75.3	77.1	-1.8
Xanomeline Low Dose		Week 16	75.3	77.1	-1.8
Xanomeline Low Dose		Week 2	78.5	77.1	1.4
Xanomeline Low Dose		Week 20	77.1	77.1	0.0
Xanomeline Low Dose		Week 24	76.2	77.1	-0.9
Xanomeline Low Dose		Week 26	75.3	77.1	-1.8
Xanomeline Low Dose		Week 4	77.6	77.1	0.5
Xanomeline Low Dose		Week 6	76.7	77.1	-0.5
Xanomeline Low Dose		Week 8	76.7	77.1	-0.5
Xanomeline Low Dose		Week 2	69.4	70.8	-1.4
Placebo		Week 12	56.2	56.2	0.0
Placebo		Week 16	56.7	56.2	0.5
Placebo		Week 2	56.2	56.2	0.0
Placebo		Week 20	57.1	56.2	0.9
Placebo		Week 24	57.1	56.2	0.9
Placebo		Week 4	56.2	56.2	0.0
Placebo		Week 6	56.7	56.2	0.5
Placebo		Week 8	56.2	56.2	0.0
Placebo		Week 12	67.1	64.9	2.3
Placebo		Week 16	65.8	64.9	0.9
Placebo		Week 2	65.3	64.9	0.5
Placebo		Week 20	64.9	64.9	0.0
Placebo		Week 24	65.3	64.9	0.5
Placebo		Week 26	65.3	64.9	0.5
Placebo		Week 4	66.2	64.9	1.4
Placebo		Week 6	66.7	64.9	1.8
Placebo		Week 8	65.8	64.9	0.9
Xanomeline High Dose		Week 12	84.4	84.8	-0.4
Xanomeline High Dose		Week 16	84.8	84.8	0.0
Xanomeline High Dose		Week 2	86.2	84.8	1.4
Xanomeline High Dose		Week 20	84.4	84.8	-0.4
Xanomeline High Dose		Week 24	83.0	84.8	-1.8
Xanomeline High Dose		Week 26	83.0	84.8	-1.8
Xanomeline High Dose		Week 4	85.3	84.8	0.5
Xanomeline High Dose		Week 6	85.3	84.8	0.5
Xanomeline High Dose		Week 8	85.3	84.8	0.5
Placebo		Week 2	60.8	59.4	1.4
Placebo		Week 12	82.1	81.2	0.9
Placebo		Week 16	81.2	81.2	0.0
Placebo		Week 2	81.2	81.2	0.0
Placebo		Week 20	81.2	81.2	0.0
Placebo		Week 24	81.7	81.2	0.5
Placebo		Week 26	81.2	81.2	0.0
Placebo		Week 4	80.7	81.2	-0.5
Placebo		Week 6	81.7	81.2	0.5
Placebo		Week 8	81.7	81.2	0.5
Placebo		Week 12	78.0	76.7	1.4
Placebo		Week 16	78.5	76.7	1.8
Placebo		Week 2	77.1	76.7	0.5
Placebo		Week 20	74.8	76.7	-1.8
Placebo		Week 24	76.7	76.7	0.0
Placebo		Week 26	76.2	76.7	-0.5
Placebo		Week 4	78.0	76.7	1.4
Placebo		Week 6	78.5	76.7	1.8
Placebo		Week 8	78.5	76.7	1.8
Xanomeline Low Dose		Week 2	56.7	56.7	0.0
Xanomeline Low Dose		Week 4	57.1	56.7	0.4
Xanomeline Low Dose		Week 6	57.1	56.7	0.4
Placebo		Week 12	49.9	49.4	0.5
Placebo		Week 16	50.4	49.4	0.9
Placebo		Week 2	48.5	49.4	-0.9
Placebo		Week 20	49.9	49.4	0.5
Placebo		Week 24	49.4	49.4	0.0
Placebo		Week 26	48.5	49.4	-0.9
Placebo		Week 4	48.5	49.4	-0.9
Placebo		Week 6	49.0	49.4	-0.4
Placebo		Week 8	49.0	49.4	-0.4
Xanomeline Low Dose		Week 12	105.7	106.1	-0.5
Xanomeline Low Dose		Week 16	106.6	106.1	0.5
Xanomeline Low Dose		Week 2	104.8	106.1	-1.4
Xanomeline Low Dose		Week 20	106.6	106.1	0.5
Xanomeline Low Dose		Week 24	106.1	106.1	0.0
Xanomeline Low Dose		Week 26	104.8	106.1	-1.4
Xanomeline Low Dose		Week 4	105.7	106.1	-0.5
Xanomeline Low Dose		Week 6	106.1	106.1	0.0
Xanomeline Low Dose		Week 8	106.1	106.1	0.0
Xanomeline High Dose		Week 2	104.3	101.6	2.7
Xanomeline High Dose		Week 4	103.0	101.6	1.4
Xanomeline Low Dose		Week 2	54.4	54.4	0.0
Xanomeline Low Dose		Week 4	54.4	54.4	0.0
Xanomeline Low Dose		Week 6	54.4	54.4	0.0
Xanomeline Low Dose		Week 8	54.0	54.4	-0.5
Placebo		Week 12	76.7	74.4	2.3
Placebo		Week 16	75.8	74.4	1.4
Placebo		Week 2	73.0	74.4	-1.4
Placebo		Week 20	74.4	74.4	0.0
Placebo		Week 24	74.4	74.4	0.0
Placebo		Week 26	74.4	74.4	0.0
Placebo		Week 4	73.9	74.4	-0.5
Placebo		Week 6	73.5	74.4	-0.9
Placebo		Week 8	74.4	74.4	0.0
Xanomeline High Dose		Week 12	88.9	87.1	1.8
Xanomeline High Dose		Week 2	87.1	87.1	0.0
Xanomeline High Dose		Week 4	87.5	87.1	0.5
Xanomeline High Dose		Week 6	89.4	87.1	2.3
Xanomeline High Dose		Week 8	89.4	87.1	2.3
Xanomeline Low Dose		Week 12	94.8	95.7	-0.9
Xanomeline Low Dose		Week 2	98.9	95.7	3.2
Xanomeline Low Dose		Week 4	95.7	95.7	0.0
Xanomeline Low Dose		Week 6	95.3	95.7	-0.4
Xanomeline Low Dose		Week 8	95.3	95.7	-0.4
Placebo		Week 2	80.7	81.2	-0.5
Placebo		Week 4	83.9	81.2	2.7
Placebo		Week 12	63.5	61.2	2.3
Placebo		Week 16	63.5	61.2	2.3
Placebo		Week 2	62.1	61.2	0.9
Placebo		Week 20	65.3	61.2	4.1
Placebo		Week 24	63.5	61.2	2.3
Placebo		Week 26	62.6	61.2	1.4
Placebo		Week 4	62.6	61.2	1.4
Placebo		Week 6	62.6	61.2	1.4
Placebo		Week 8	62.6	61.2	1.4
Xanomeline Low Dose		Week 12	52.6	47.2	5.4
Xanomeline Low Dose		Week 16	51.7	47.2	4.5
Xanomeline Low Dose		Week 2	50.8	47.2	3.6
Xanomeline Low Dose		Week 4	51.7	47.2	4.5
Xanomeline Low Dose		Week 6	51.7	47.2	4.5
Xanomeline Low Dose		Week 8	50.8	47.2	3.6
Xanomeline Low Dose		Week 2	67.1	68.0	-0.9
Xanomeline Low Dose		Week 4	68.0	68.0	0.0
Xanomeline Low Dose		Week 6	68.0	68.0	0.0
Placebo		Week 12	47.2	49.9	-2.7
Placebo		Week 16	46.3	49.9	-3.6
Placebo		Week 2	49.0	49.9	-0.9
Placebo		Week 20	46.7	49.9	-3.2
Placebo		Week 24	45.4	49.9	-4.5
Placebo		Week 26	45.4	49.9	-4.5
Placebo		Week 4	48.5	49.9	-1.4
Placebo		Week 6	47.6	49.9	-2.3
Placebo		Week 8	47.2	49.9	-2.7
Xanomeline High Dose		Week 12	59.0	59.4	-0.5
Xanomeline High Dose		Week 16	60.3	59.4	0.9
Xanomeline High Dose		Week 2	59.0	59.4	-0.5
Xanomeline High Dose		Week 20	59.0	59.4	-0.5
Xanomeline High Dose		Week 24	59.0	59.4	-0.5
Xanomeline High Dose		Week 4	61.7	59.4	2.3
Xanomeline High Dose		Week 6	60.8	59.4	1.4
Xanomeline High Dose		Week 8	61.7	59.4	2.3
Xanomeline High Dose		Week 12	56.2	56.2	0.0
Xanomeline High Dose		Week 16	54.4	56.2	-1.8
Xanomeline High Dose		Week 2	57.6	56.2	1.4
Xanomeline High Dose		Week 4	57.1	56.2	0.9
Xanomeline High Dose		Week 6	56.7	56.2	0.5
Xanomeline High Dose		Week 8	56.7	56.2	0.5
Placebo		Week 12	45.4	45.4	0.0
Placebo		Week 16	45.4	45.4	0.0
Placebo		Week 2	45.4	45.4	0.0
Placebo		Week 20	44.0	45.4	-1.4
Placebo		Week 24	43.5	45.4	-1.8
Placebo		Week 26	43.5	45.4	-1.8
Placebo		Week 4	44.5	45.4	-0.9
Placebo		Week 6	44.5	45.4	-0.9
Placebo		Week 8	45.4	45.4	0.0
Xanomeline High Dose		Week 2	53.5	55.3	-1.8
Xanomeline High Dose		Week 4	53.5	55.3	-1.8
Xanomeline Low Dose		Week 12	80.3	76.2	4.1
Xanomeline Low Dose		Week 16	75.8	76.2	-0.5
Xanomeline Low Dose		Week 2	77.6	76.2	1.4
Xanomeline Low Dose		Week 20	74.4	76.2	-1.8
Xanomeline Low Dose		Week 24	70.8	76.2	-5.4
Xanomeline Low Dose		Week 26	71.2	76.2	-5.0
Xanomeline Low Dose		Week 4	78.0	76.2	1.8
Xanomeline Low Dose		Week 6	78.5	76.2	2.3
Xanomeline Low Dose		Week 8	78.5	76.2	2.3
Xanomeline High Dose		Week 12	62.6	63.5	-0.9
Xanomeline High Dose		Week 16	63.5	63.5	0.0
Xanomeline High Dose		Week 2	63.0	63.5	-0.5
Xanomeline High Dose		Week 20	63.5	63.5	0.0
Xanomeline High Dose		Week 24	62.6	63.5	-0.9
Xanomeline High Dose		Week 26	63.5	63.5	0.0
Xanomeline High Dose		Week 4	63.5	63.5	0.0
Xanomeline High Dose		Week 6	61.7	63.5	-1.8
Xanomeline High Dose		Week 8	62.6	63.5	-0.9
Xanomeline High Dose		Week 2	46.7	46.7	0.0
Xanomeline High Dose		Week 4	47.2	46.7	0.5
Xanomeline Low Dose		Week 2	66.2	66.7	-0.5
Placebo		Week 12	80.7	81.0	-0.2
Placebo		Week 16	80.5	81.0	-0.5
Placebo		Week 2	80.7	81.0	-0.2
Placebo		Week 4	80.7	81.0	-0.2
Placebo		Week 6	80.3	81.0	-0.7
Placebo		Week 8	80.7	81.0	-0.2
Xanomeline High Dose		Week 2	63.0	63.0	0.0
Xanomeline Low Dose		Week 2	55.8	55.5	0.3
Xanomeline High Dose		Week 2	80.7	80.7	0.0
Xanomeline High Dose		Week 4	80.3	80.7	-0.4
Xanomeline High Dose		Week 6	79.8	80.7	-0.9
Xanomeline High Dose		Week 8	80.5	80.7	-0.2
Xanomeline High Dose		Week 2	75.8	75.8	0.0
Xanomeline High Dose		Week 4	75.3	75.8	-0.5
Xanomeline High Dose		Week 6	76.2	75.8	0.5
Xanomeline High Dose		Week 12	73.0	73.5	-0.5
Xanomeline High Dose		Week 2	73.7	73.5	0.2
Xanomeline High Dose		Week 4	73.5	73.5	0.0
Xanomeline High Dose		Week 6	73.5	73.5	0.0
Xanomeline High Dose		Week 8	73.5	73.5	0.0
Xanomeline Low Dose		Week 12	78.0	77.8	0.2
Xanomeline Low Dose		Week 16	78.9	77.8	1.1
Xanomeline Low Dose		Week 2	77.6	77.8	-0.2
Xanomeline Low Dose		Week 20	78.5	77.8	0.7
Xanomeline Low Dose		Week 4	77.6	77.8	-0.2
Xanomeline Low Dose		Week 6	78.5	77.8	0.7
Xanomeline Low Dose		Week 8	78.0	77.8	0.2
Xanomeline Low Dose		Week 2	49.0	51.7	-2.7
Xanomeline Low Dose		Week 4	48.1	51.7	-3.6
Xanomeline Low Dose		Week 6	48.5	51.7	-3.2
Xanomeline Low Dose		Week 8	49.0	51.7	-2.7
Placebo		Week 12	42.2	41.0	1.1
Placebo		Week 16	42.4	41.0	1.4
Placebo		Week 2	42.6	41.0	1.6
Placebo		Week 20	42.6	41.0	1.6
Placebo		Week 24	42.6	41.0	1.6
Placebo		Week 26	43.1	41.0	2.0
Placebo		Week 4	41.7	41.0	0.7
Placebo		Week 6	42.6	41.0	1.6
Placebo		Week 8	42.6	41.0	1.6
Xanomeline Low Dose		Week 12	63.5	64.4	-0.9
Xanomeline Low Dose		Week 16	63.7	64.4	-0.7
Xanomeline Low Dose		Week 2	64.4	64.4	0.0
Xanomeline Low Dose		Week 20	61.2	64.4	-3.2
Xanomeline Low Dose		Week 24	62.1	64.4	-2.3
Xanomeline Low Dose		Week 26	61.5	64.4	-2.9
Xanomeline Low Dose		Week 4	64.9	64.4	0.5
Xanomeline Low Dose		Week 6	64.4	64.4	0.0
Xanomeline Low Dose		Week 8	64.0	64.4	-0.4
Placebo		Week 12	50.4	49.9	0.5
Placebo		Week 16	51.7	49.9	1.8
Placebo		Week 2	49.0	49.9	-0.9
Placebo		Week 20	51.7	49.9	1.8
Placebo		Week 24	51.7	49.9	1.8
Placebo		Week 26	50.8	49.9	0.9
Placebo		Week 4	49.0	49.9	-0.9
Placebo		Week 6	50.8	49.9	0.9
Placebo		Week 8	49.9	49.9	0.0
Xanomeline Low Dose		Week 12	56.2	54.4	1.8
Xanomeline Low Dose		Week 16	54.4	54.4	0.0
Xanomeline Low Dose		Week 2	55.8	54.4	1.4
Xanomeline Low Dose		Week 20	54.4	54.4	0.0
Xanomeline Low Dose		Week 24	55.3	54.4	0.9
Xanomeline Low Dose		Week 26	55.3	54.4	0.9
Xanomeline Low Dose		Week 4	56.2	54.4	1.8
Xanomeline Low Dose		Week 6	54.0	54.4	-0.5
Xanomeline Low Dose		Week 8	55.3	54.4	0.9
Placebo		Week 2	47.6	46.3	1.4
Xanomeline High Dose		Week 2	73.3	73.0	0.2
Xanomeline High Dose		Week 4	76.7	73.0	3.6
Xanomeline High Dose		Week 6	73.0	73.0	0.0
Placebo		Week 2	48.5	48.8	-0.2
Placebo		Week 4	48.1	48.8	-0.7
Placebo		Week 6	48.5	48.8	-0.2
Placebo		Week 8	47.9	48.8	-0.9
Xanomeline High Dose		Week 2	88.0	88.5	-0.5
Xanomeline High Dose		Week 4	88.0	88.5	-0.5
Xanomeline High Dose		Week 6	87.5	88.5	-0.9
Xanomeline High Dose		Week 8	88.0	88.5	-0.5
Xanomeline Low Dose		Week 2	60.3	59.9	0.4
Xanomeline Low Dose		Week 4	59.6	59.9	-0.2
Xanomeline Low Dose		Week 2	68.0	68.5	-0.4
Xanomeline Low Dose		Week 4	68.5	68.5	0.0
Xanomeline Low Dose		Week 6	68.0	68.5	-0.4
Xanomeline Low Dose		Week 8	68.5	68.5	0.0
Xanomeline High Dose		Week 2	77.1	78.5	-1.4
Xanomeline High Dose		Week 4	78.5	78.5	0.0
Xanomeline High Dose		Week 6	77.1	78.5	-1.4
Xanomeline High Dose		Week 8	77.6	78.5	-0.9
Placebo		Week 12	73.0	73.5	-0.5
Placebo		Week 16	75.3	73.5	1.8
Placebo		Week 2	73.5	73.5	0.0
Placebo		Week 20	75.3	73.5	1.8
Placebo		Week 24	75.3	73.5	1.8
Placebo		Week 26	74.8	73.5	1.4
Placebo		Week 4	74.8	73.5	1.4
Placebo		Week 6	74.4	73.5	0.9
Placebo		Week 8	73.9	73.5	0.5
Placebo		Week 12	57.6	58.5	-0.9
Placebo		Week 16	57.6	58.5	-0.9
Placebo		Week 2	59.0	58.5	0.5
Placebo		Week 20	58.1	58.5	-0.4
Placebo		Week 24	58.5	58.5	0.0
Placebo		Week 4	58.3	58.5	-0.2
Placebo		Week 6	58.1	58.5	-0.4
Placebo		Week 8	58.5	58.5	0.0
Placebo		Week 2	76.7	76.2	0.5
Placebo		Week 4	76.7	76.2	0.5
Placebo		Week 6	76.2	76.2	0.0
Placebo		Week 12	71.7	72.1	-0.5
Placebo		Week 16	71.7	72.1	-0.5
Placebo		Week 2	72.6	72.1	0.5
Placebo		Week 20	72.1	72.1	0.0
Placebo		Week 4	72.6	72.1	0.5
Placebo		Week 6	71.7	72.1	-0.5
Placebo		Week 8	72.1	72.1	0.0
Xanomeline Low Dose		Week 2	73.0	71.7	1.4
Placebo		Week 12	56.2	54.0	2.3
Placebo		Week 16	57.1	54.0	3.2
Placebo		Week 2	54.4	54.0	0.5
Placebo		Week 4	55.3	54.0	1.4
Placebo		Week 6	55.3	54.0	1.4
Placebo		Week 8	55.3	54.0	1.4
Placebo		Week 2	39.0	39.9	-0.9
Xanomeline High Dose		Week 12	66.7	69.4	-2.7
Xanomeline High Dose		Week 16	66.7	69.4	-2.7
Xanomeline High Dose		Week 2	69.4	69.4	0.0
Xanomeline High Dose		Week 20	66.7	69.4	-2.7
Xanomeline High Dose		Week 24	65.8	69.4	-3.6
Xanomeline High Dose		Week 26	66.7	69.4	-2.7
Xanomeline High Dose		Week 4	68.0	69.4	-1.4
Xanomeline High Dose		Week 6	68.5	69.4	-0.9
Xanomeline High Dose		Week 8	68.0	69.4	-1.4
Xanomeline High Dose		Week 12	72.1	73.0	-0.9
Xanomeline High Dose		Week 2	73.0	73.0	0.0
Xanomeline High Dose		Week 4	73.0	73.0	0.0
Xanomeline High Dose		Week 6	72.6	73.0	-0.5
Xanomeline High Dose		Week 8	72.6	73.0	-0.5
Placebo		Week 12	72.1	73.0	-0.9
Placebo		Week 16	72.1	73.0	-0.9
Placebo		Week 2	71.2	73.0	-1.8
Placebo		Week 20	68.5	73.0	-4.5
Placebo		Week 24	73.0	73.0	0.0
Placebo		Week 26	72.6	73.0	-0.5
Placebo		Week 4	73.0	73.0	0.0
Placebo		Week 6	73.0	73.0	0.0
Placebo		Week 8	72.6	73.0	-0.5
Xanomeline Low Dose		Week 12	74.4	75.3	-0.9
Xanomeline Low Dose		Week 16	73.0	75.3	-2.3
Xanomeline Low Dose		Week 2	76.7	75.3	1.4
Xanomeline Low Dose		Week 20	73.9	75.3	-1.4
Xanomeline Low Dose		Week 24	73.9	75.3	-1.4
Xanomeline Low Dose		Week 4	75.3	75.3	0.0
Xanomeline Low Dose		Week 6	74.8	75.3	-0.5
Xanomeline Low Dose		Week 8	75.3	75.3	0.0
Xanomeline High Dose		Week 2	84.4	84.4	0.0
Xanomeline High Dose		Week 12	48.1	48.5	-0.5
Xanomeline High Dose		Week 2	50.4	48.5	1.8
Xanomeline High Dose		Week 4	48.5	48.5	0.0
Xanomeline High Dose		Week 6	48.5	48.5	0.0
Xanomeline High Dose		Week 8	48.1	48.5	-0.5
Placebo		Week 12	55.8	44.5	11.3
Placebo		Week 16	55.8	44.5	11.3
Placebo		Week 2	43.1	44.5	-1.4
Placebo		Week 20	50.8	44.5	6.3
Placebo		Week 24	52.6	44.5	8.2
Placebo		Week 26	43.1	44.5	-1.4
Placebo		Week 4	44.0	44.5	-0.5
Placebo		Week 6	44.0	44.5	-0.5
Placebo		Week 8	43.5	44.5	-0.9
Xanomeline High Dose		Week 2	56.7	57.1	-0.4
Xanomeline Low Dose		Week 12	55.3	56.2	-0.9
Xanomeline Low Dose		Week 16	52.6	56.2	-3.6
Xanomeline Low Dose		Week 2	56.2	56.2	0.0
Xanomeline Low Dose		Week 4	55.8	56.2	-0.5
Xanomeline Low Dose		Week 6	54.7	56.2	-1.6
Xanomeline Low Dose		Week 8	55.8	56.2	-0.5
Xanomeline Low Dose		Week 12	54.4	54.4	0.0
Xanomeline Low Dose		Week 16	55.3	54.4	0.9
Xanomeline Low Dose		Week 2	54.4	54.4	0.0
Xanomeline Low Dose		Week 20	54.9	54.4	0.5
Xanomeline Low Dose		Week 24	54.9	54.4	0.5
Xanomeline Low Dose		Week 26	54.9	54.4	0.5
Xanomeline Low Dose		Week 4	54.4	54.4	0.0
Xanomeline Low Dose		Week 6	54.4	54.4	0.0
Xanomeline Low Dose		Week 8	54.9	54.4	0.5
Placebo		Week 12	54.2	58.7	-4.5
Placebo		Week 16	54.6	58.7	-4.1
Placebo		Week 2	56.9	58.7	-1.8
Placebo		Week 20	54.4	58.7	-4.3
Placebo		Week 24	54.8	58.7	-4.0
Placebo		Week 4	57.1	58.7	-1.6
Placebo		Week 6	53.5	58.7	-5.2
Placebo		Week 8	54.4	58.7	-4.3
Xanomeline High Dose		Week 2	58.3	57.8	0.5
Xanomeline High Dose		Week 4	59.0	57.8	1.1
Placebo		Week 12	75.3	74.4	0.9
Placebo		Week 16	73.5	74.4	-0.9
Placebo		Week 2	75.3	74.4	0.9
Placebo		Week 20	73.5	74.4	-0.9
Placebo		Week 24	73.5	74.4	-0.9
Placebo		Week 4	75.3	74.4	0.9
Placebo		Week 6	74.4	74.4	0.0
Placebo		Week 8	74.4	74.4	0.0
Xanomeline Low Dose		Week 2	83.0	82.6	0.5
Xanomeline Low Dose		Week 12	49.9	50.4	-0.5
Xanomeline Low Dose		Week 16	49.9	50.4	-0.5
Xanomeline Low Dose		Week 2	49.0	50.4	-1.4
Xanomeline Low Dose		Week 20	50.8	50.4	0.4
Xanomeline Low Dose		Week 24	51.3	50.4	0.9
Xanomeline Low Dose		Week 26	51.7	50.4	1.4
Xanomeline Low Dose		Week 4	49.4	50.4	-0.9
Xanomeline Low Dose		Week 6	49.9	50.4	-0.5
Xanomeline Low Dose		Week 8	53.5	50.4	3.2
Placebo		Week 12	71.7	66.7	5.0
Placebo		Week 16	71.2	66.7	4.5
Placebo		Week 20	71.7	66.7	5.0
Placebo		Week 24	70.3	66.7	3.6
Placebo		Week 26	70.8	66.7	4.1
Placebo		Week 4	71.2	66.7	4.5
Placebo		Week 6	70.8	66.7	4.1
Placebo		Week 8	71.2	66.7	4.5
Placebo		Week 2	74.4	73.5	0.9
Placebo		Week 4	74.4	73.5	0.9
Placebo		Week 12	57.1	54.9	2.3
Placebo		Week 16	58.1	54.9	3.2
Placebo		Week 2	54.0	54.9	-0.9
Placebo		Week 20	59.0	54.9	4.1
Placebo		Week 24	59.9	54.9	5.0
Placebo		Week 26	59.9	54.9	5.0
Placebo		Week 4	54.9	54.9	0.0
Placebo		Week 6	55.8	54.9	0.9
Placebo		Week 8	56.2	54.9	1.4
Xanomeline High Dose		Week 12	64.4	62.8	1.6
Xanomeline High Dose		Week 2	63.0	62.8	0.2
Xanomeline High Dose		Week 4	63.0	62.8	0.2
Xanomeline High Dose		Week 6	64.0	62.8	1.1
Xanomeline High Dose		Week 8	63.0	62.8	0.2
Xanomeline Low Dose		Week 2	42.6	41.7	0.9
Xanomeline High Dose		Week 2	78.5	77.1	1.4
Xanomeline High Dose		Week 4	78.5	77.1	1.4
Placebo		Week 12	78.0	75.8	2.3
Placebo		Week 16	78.0	75.8	2.3
Placebo		Week 2	77.1	75.8	1.4
Placebo		Week 20	77.6	75.8	1.8
Placebo		Week 24	76.2	75.8	0.5
Placebo		Week 26	74.4	75.8	-1.4
Placebo		Week 4	78.0	75.8	2.3
Placebo		Week 6	78.0	75.8	2.3
Placebo		Week 8	77.6	75.8	1.8
Xanomeline Low Dose		Week 2	75.8	74.4	1.4
Xanomeline Low Dose		Week 4	73.9	74.4	-0.5
Xanomeline Low Dose		Week 6	74.8	74.4	0.5
Placebo		Week 12	78.9	76.2	2.7
Placebo		Week 16	78.5	76.2	2.3
Placebo		Week 2	78.5	76.2	2.3
Placebo		Week 20	78.5	76.2	2.3
Placebo		Week 24	75.8	76.2	-0.5
Placebo		Week 26	73.5	76.2	-2.7
Placebo		Week 4	76.2	76.2	0.0
Placebo		Week 6	78.9	76.2	2.7
Placebo		Week 8	78.9	76.2	2.7
Placebo		Week 12	79.4	80.7	-1.4
Placebo		Week 16	77.1	80.7	-3.6
Placebo		Week 2	81.7	80.7	0.9
Placebo		Week 20	78.9	80.7	-1.8
Placebo		Week 24	78.9	80.7	-1.8
Placebo		Week 26	79.4	80.7	-1.4
Placebo		Week 4	79.8	80.7	-0.9
Placebo		Week 6	80.3	80.7	-0.4
Placebo		Week 8	78.5	80.7	-2.3
Xanomeline Low Dose		Week 12	84.4	78.9	5.4
Xanomeline Low Dose		Week 2	82.1	78.9	3.2
Xanomeline Low Dose		Week 4	82.6	78.9	3.6
Xanomeline Low Dose		Week 6	82.1	78.9	3.2
Xanomeline Low Dose		Week 8	83.5	78.9	4.5
Placebo		Week 12	59.4	59.9	-0.5
Placebo		Week 16	59.9	59.9	0.0
Placebo		Week 2	60.8	59.9	0.9
Placebo		Week 20	59.4	59.9	-0.5
Placebo		Week 24	59.9	59.9	0.0
Placebo		Week 26	59.9	59.9	0.0
Placebo		Week 4	59.9	59.9	0.0
Placebo		Week 6	59.4	59.9	-0.5
Placebo		Week 8	59.4	59.9	-0.5
Xanomeline High Dose		Week 12	83.9	87.5	-3.6
Xanomeline High Dose		Week 16	84.8	87.5	-2.7
Xanomeline High Dose		Week 2	87.5	87.5	0.0
Xanomeline High Dose		Week 20	83.9	87.5	-3.6
Xanomeline High Dose		Week 24	83.0	87.5	-4.5
Xanomeline High Dose		Week 26	83.9	87.5	-3.6
Xanomeline High Dose		Week 4	85.3	87.5	-2.3
Xanomeline High Dose		Week 6	86.6	87.5	-0.9
Xanomeline High Dose		Week 8	86.2	87.5	-1.4
Placebo		Week 12	59.0	59.0	0.0
Placebo		Week 16	59.0	59.0	0.0
Placebo		Week 2	57.6	59.0	-1.4
Placebo		Week 20	59.4	59.0	0.5
Placebo		Week 24	58.1	59.0	-0.9
Placebo		Week 26	59.0	59.0	0.0
Placebo		Week 4	58.5	59.0	-0.5
Placebo		Week 6	58.5	59.0	-0.5
Placebo		Week 8	58.1	59.0	-0.9
Xanomeline High Dose		Week 12	77.1	74.8	2.3
Xanomeline High Dose		Week 2	74.8	74.8	0.0
Xanomeline High Dose		Week 4	76.2	74.8	1.4
Xanomeline High Dose		Week 6	76.7	74.8	1.8
Xanomeline High Dose		Week 8	77.1	74.8	2.3
Xanomeline Low Dose		Week 12	60.8	60.3	0.5
Xanomeline Low Dose		Week 16	60.3	60.3	0.0
Xanomeline Low Dose		Week 2	60.8	60.3	0.5
Xanomeline Low Dose		Week 20	59.9	60.3	-0.4
Xanomeline Low Dose		Week 24	59.4	60.3	-0.9
Xanomeline Low Dose		Week 26	64.0	60.3	3.6
Xanomeline Low Dose		Week 4	60.8	60.3	0.5
Xanomeline Low Dose		Week 6	62.6	60.3	2.3
Xanomeline Low Dose		Week 8	62.1	60.3	1.8
Xanomeline Low Dose		Week 2	50.4	50.4	0.0
Xanomeline Low Dose		Week 4	51.7	50.4	1.4
Xanomeline Low Dose		Week 6	50.4	50.4	0.0
Placebo		Week 12	70.3	70.3	0.0
Placebo		Week 16	69.8	70.3	-0.5
Placebo		Week 2	71.7	70.3	1.4
Placebo		Week 20	68.5	70.3	-1.8
Placebo		Week 4	71.7	70.3	1.4
Placebo		Week 6	70.8	70.3	0.5
Placebo		Week 8	70.3	70.3	0.0
Xanomeline High Dose		Week 12	55.8	54.9	0.9
Xanomeline High Dose		Week 16	55.8	54.9	0.9
Xanomeline High Dose		Week 2	55.8	54.9	0.9
Xanomeline High Dose		Week 20	57.1	54.9	2.3
Xanomeline High Dose		Week 24	56.7	54.9	1.8
Xanomeline High Dose		Week 26	56.7	54.9	1.8
Xanomeline High Dose		Week 4	55.8	54.9	0.9
Xanomeline High Dose		Week 6	56.2	54.9	1.4
Xanomeline High Dose		Week 8	55.3	54.9	0.5
Xanomeline Low Dose		Week 2	60.8	59.0	1.8
Xanomeline Low Dose		Week 4	60.8	59.0	1.8
Placebo		Week 12	73.0	73.0	0.0
Placebo		Week 16	71.7	73.0	-1.4
Placebo		Week 2	73.0	73.0	0.0
Placebo		Week 20	71.2	73.0	-1.8
Placebo		Week 24	71.2	73.0	-1.8
Placebo		Week 26	71.7	73.0	-1.4
Placebo		Week 4	72.6	73.0	-0.5
Placebo		Week 6	73.9	73.0	0.9
Placebo		Week 8	72.6	73.0	-0.5
Xanomeline Low Dose		Week 2	60.3	59.9	0.4
Xanomeline Low Dose		Week 12	52.6	54.4	-1.8
Xanomeline Low Dose		Week 16	52.2	54.4	-2.3
Xanomeline Low Dose		Week 2	54.9	54.4	0.5
Xanomeline Low Dose		Week 20	53.8	54.4	-0.7
Xanomeline Low Dose		Week 24	53.5	54.4	-0.9
Xanomeline Low Dose		Week 26	52.2	54.4	-2.3
Xanomeline Low Dose		Week 4	54.9	54.4	0.5
Xanomeline Low Dose		Week 6	54.0	54.4	-0.5
Xanomeline Low Dose		Week 8	52.6	54.4	-1.8
Xanomeline High Dose		Week 12	69.8	69.0	0.9
Xanomeline High Dose		Week 16	69.8	69.0	0.9
Xanomeline High Dose		Week 2	70.5	69.0	1.6
Xanomeline High Dose		Week 20	66.7	69.0	-2.3
Xanomeline High Dose		Week 24	67.1	69.0	-1.8
Xanomeline High Dose		Week 26	66.2	69.0	-2.7
Xanomeline High Dose		Week 4	70.8	69.0	1.8
Xanomeline High Dose		Week 6	71.0	69.0	2.0
Xanomeline High Dose		Week 8	70.5	69.0	1.6
Xanomeline Low Dose		Week 12	57.1	56.5	0.7
Xanomeline Low Dose		Week 2	56.5	56.5	0.0
Xanomeline Low Dose		Week 4	56.2	56.5	-0.2
Xanomeline Low Dose		Week 6	56.2	56.5	-0.2
Xanomeline Low Dose		Week 8	58.1	56.5	1.6
Placebo		Week 12	78.0	79.4	-1.4
Placebo		Week 16	77.1	79.4	-2.3
Placebo		Week 2	78.9	79.4	-0.4
Placebo		Week 20	76.2	79.4	-3.2
Placebo		Week 24	76.2	79.4	-3.2
Placebo		Week 26	74.8	79.4	-4.5
Placebo		Week 4	79.4	79.4	0.0
Placebo		Week 6	79.4	79.4	0.0
Placebo		Week 8	78.9	79.4	-0.4
Xanomeline High Dose		Week 12	53.5	53.5	0.0
Xanomeline High Dose		Week 16	53.5	53.5	0.0
Xanomeline High Dose		Week 2	53.5	53.5	0.0
Xanomeline High Dose		Week 20	52.6	53.5	-0.9
Xanomeline High Dose		Week 24	53.5	53.5	0.0
Xanomeline High Dose		Week 26	52.2	53.5	-1.4
Xanomeline High Dose		Week 4	54.9	53.5	1.4
Xanomeline High Dose		Week 6	55.8	53.5	2.3
Xanomeline High Dose		Week 8	54.0	53.5	0.5
Xanomeline Low Dose		Week 2	88.9	88.9	0.0
Xanomeline Low Dose		Week 4	87.5	88.9	-1.4
Xanomeline Low Dose		Week 6	86.6	88.9	-2.3
Xanomeline Low Dose		Week 8	85.3	88.9	-3.6
Xanomeline High Dose		Week 2	63.5	62.1	1.4
Xanomeline High Dose		Week 4	63.0	62.1	0.9
Xanomeline High Dose		Week 6	63.5	62.1	1.4
Xanomeline Low Dose		Week 12	68.0	68.0	0.0
Xanomeline Low Dose		Week 2	69.0	68.0	0.9
Xanomeline Low Dose		Week 4	69.0	68.0	0.9
Xanomeline Low Dose		Week 6	68.5	68.0	0.4
Xanomeline Low Dose		Week 8	68.5	68.0	0.4
Xanomeline High Dose		Week 2	80.5	82.6	-2.0
Xanomeline High Dose		Week 4	82.6	82.6	0.0
Xanomeline High Dose		Week 6	81.2	82.6	-1.4
Xanomeline High Dose		Week 8	78.0	82.6	-4.5
Placebo		Week 12	65.3	65.3	0.0
Placebo		Week 16	66.7	65.3	1.4
Placebo		Week 2	65.3	65.3	0.0
Placebo		Week 20	68.0	65.3	2.7
Placebo		Week 4	66.7	65.3	1.4
Placebo		Week 6	67.1	65.3	1.8
Placebo		Week 8	65.3	65.3	0.0
Xanomeline Low Dose		Week 2	65.3	64.9	0.5
Xanomeline Low Dose		Week 4	66.7	64.9	1.8
Xanomeline Low Dose		Week 6	66.7	64.9	1.8
Xanomeline Low Dose		Week 8	66.7	64.9	1.8
Placebo		Week 12	48.1	50.4	-2.3
Placebo		Week 16	47.6	50.4	-2.7
Placebo		Week 2	49.4	50.4	-0.9
Placebo		Week 20	49.7	50.4	-0.7
Placebo		Week 24	49.7	50.4	-0.7
Placebo		Week 26	49.9	50.4	-0.5
Placebo		Week 4	50.8	50.4	0.4
Placebo		Week 6	50.8	50.4	0.4
Placebo		Week 8	50.8	50.4	0.4
Placebo		Week 12	44.9	44.5	0.5
Placebo		Week 16	44.0	44.5	-0.5
Placebo		Week 2	44.9	44.5	0.5
Placebo		Week 4	44.9	44.5	0.5
Placebo		Week 6	44.9	44.5	0.5
Placebo		Week 8	44.9	44.5	0.5
Xanomeline High Dose		Week 12	78.0	78.5	-0.5
Xanomeline High Dose		Week 16	78.5	78.5	0.0
Xanomeline High Dose		Week 2	78.9	78.5	0.5
Xanomeline High Dose		Week 20	78.9	78.5	0.5
Xanomeline High Dose		Week 24	77.1	78.5	-1.4
Xanomeline High Dose		Week 26	78.0	78.5	-0.5
Xanomeline High Dose		Week 4	79.4	78.5	0.9
Xanomeline High Dose		Week 6	78.9	78.5	0.5
Xanomeline High Dose		Week 8	79.4	78.5	0.9
Placebo		Week 12	54.4	53.5	0.9
Placebo		Week 16	54.4	53.5	0.9
Placebo		Week 2	54.0	53.5	0.5
Placebo		Week 20	54.9	53.5	1.4
Placebo		Week 24	53.5	53.5	0.0
Placebo		Week 26	52.6	53.5	-0.9
Placebo		Week 4	54.9	53.5	1.4
Placebo		Week 6	56.7	53.5	3.2
Placebo		Week 8	56.7	53.5	3.2
Xanomeline Low Dose		Week 12	73.5	74.8	-1.4
Xanomeline Low Dose		Week 16	73.5	74.8	-1.4
Xanomeline Low Dose		Week 2	74.8	74.8	0.0
Xanomeline Low Dose		Week 20	72.6	74.8	-2.3
Xanomeline Low Dose		Week 24	70.3	74.8	-4.5
Xanomeline Low Dose		Week 26	70.3	74.8	-4.5
Xanomeline Low Dose		Week 4	74.4	74.8	-0.5
Xanomeline Low Dose		Week 6	73.9	74.8	-0.9
Xanomeline Low Dose		Week 8	73.0	74.8	-1.8
Placebo		Week 12	78.2	78.0	0.2
Placebo		Week 16	78.9	78.0	0.9
Placebo		Week 2	77.6	78.0	-0.5
Placebo		Week 20	79.4	78.0	1.4
Placebo		Week 24	79.4	78.0	1.4
Placebo		Week 26	77.6	78.0	-0.5
Placebo		Week 4	77.6	78.0	-0.5
Placebo		Week 6	78.5	78.0	0.5
Xanomeline Low Dose		Week 2	70.3	70.3	0.0
Xanomeline High Dose		Week 12	70.8	72.6	-1.8
Xanomeline High Dose		Week 16	70.3	72.6	-2.3
Xanomeline High Dose		Week 2	71.7	72.6	-0.9
Xanomeline High Dose		Week 20	69.8	72.6	-2.7
Xanomeline High Dose		Week 24	69.4	72.6	-3.2
Xanomeline High Dose		Week 4	71.2	72.6	-1.4
Xanomeline High Dose		Week 6	76.7	72.6	4.1
Xanomeline High Dose		Week 8	71.2	72.6	-1.4
Xanomeline High Dose		Week 2	55.3	56.2	-0.9
Xanomeline High Dose		Week 4	55.3	56.2	-0.9
Placebo		Week 12	69.8	70.8	-0.9
Placebo		Week 16	69.8	70.8	-0.9
Placebo		Week 2	69.4	70.8	-1.4
Placebo		Week 20	69.4	70.8	-1.4
Placebo		Week 24	69.8	70.8	-0.9
Placebo		Week 26	68.5	70.8	-2.3
Placebo		Week 4	69.0	70.8	-1.8
Placebo		Week 6	70.3	70.8	-0.5
Placebo		Week 8	70.3	70.8	-0.5
Xanomeline Low Dose		Week 2	58.1	58.1	0.0
Xanomeline Low Dose		Week 4	54.4	58.1	-3.6
Xanomeline Low Dose		Week 6	55.8	58.1	-2.3
Xanomeline Low Dose		Week 8	57.1	58.1	-0.9
Xanomeline Low Dose		Week 2	51.3	51.7	-0.5
Xanomeline Low Dose		Week 4	50.8	51.7	-0.9
Xanomeline Low Dose		Week 6	51.7	51.7	0.0
Placebo		Week 12	68.5	70.3	-1.8
Placebo		Week 16	69.0	70.3	-1.4
Placebo		Week 2	70.8	70.3	0.5
Placebo		Week 20	68.0	70.3	-2.3
Placebo		Week 24	69.0	70.3	-1.4
Placebo		Week 26	69.0	70.3	-1.4
Placebo		Week 4	71.2	70.3	0.9
Placebo		Week 6	67.6	70.3	-2.7
Placebo		Week 8	67.6	70.3	-2.7
Xanomeline High Dose		Week 12	49.0	49.0	0.0
Xanomeline High Dose		Week 16	48.5	49.0	-0.5
Xanomeline High Dose		Week 2	51.3	49.0	2.3
Xanomeline High Dose		Week 4	49.4	49.0	0.4
Xanomeline High Dose		Week 6	50.8	49.0	1.8
Xanomeline High Dose		Week 8	49.9	49.0	0.9
Placebo		Week 12	52.6	49.0	3.6
Placebo		Week 16	51.3	49.0	2.3
Placebo		Week 2	51.7	49.0	2.7
Placebo		Week 20	49.4	49.0	0.4
Placebo		Week 24	49.0	49.0	0.0
Placebo		Week 26	49.9	49.0	0.9
Placebo		Week 4	52.2	49.0	3.2
Placebo		Week 6	50.8	49.0	1.8
Placebo		Week 8	52.6	49.0	3.6
Placebo		Week 12	42.6	41.7	0.9
Placebo		Week 16	41.3	41.7	-0.4
Placebo		Week 2	41.7	41.7	0.0
Placebo		Week 20	40.8	41.7	-0.9
Placebo		Week 24	41.3	41.7	-0.4
Placebo		Week 26	40.8	41.7	-0.9
Placebo		Week 4	41.7	41.7	0.0
Placebo		Week 6	41.7	41.7	0.0
Placebo		Week 8	42.6	41.7	0.9
Xanomeline High Dose		Week 2	64.4	65.3	-0.9
Xanomeline High Dose		Week 4	63.5	65.3	-1.8
Xanomeline High Dose		Week 6	64.0	65.3	-1.4
Xanomeline High Dose		Week 2	57.6	57.6	0.0
Xanomeline Low Dose		Week 2	82.1	82.6	-0.5
Xanomeline Low Dose		Week 4	83.0	82.6	0.5
Xanomeline Low Dose		Week 12	54.4	54.9	-0.5
Xanomeline Low Dose		Week 2	54.9	54.9	0.0
Xanomeline Low Dose		Week 4	55.3	54.9	0.5
Xanomeline Low Dose		Week 6	54.4	54.9	-0.5
Xanomeline Low Dose		Week 8	54.4	54.9	-0.5
Placebo		Week 12	49.4	47.6	1.8
Placebo		Week 16	48.1	47.6	0.4
Placebo		Week 2	47.6	47.6	0.0
Placebo		Week 20	47.6	47.6	0.0
Placebo		Week 24	46.7	47.6	-0.9
Placebo		Week 26	47.2	47.6	-0.5
Placebo		Week 4	47.6	47.6	0.0
Placebo		Week 6	47.6	47.6	0.0
Placebo		Week 8	47.6	47.6	0.0
Xanomeline High Dose		Week 12	50.8	49.9	0.9
Xanomeline High Dose		Week 16	49.9	49.9	0.0
Xanomeline High Dose		Week 2	49.9	49.9	0.0
Xanomeline High Dose		Week 20	50.8	49.9	0.9
Xanomeline High Dose		Week 24	51.7	49.9	1.8
Xanomeline High Dose		Week 26	49.9	49.9	0.0
Xanomeline High Dose		Week 4	49.4	49.9	-0.5
Xanomeline High Dose		Week 6	49.0	49.9	-0.9
Xanomeline High Dose		Week 8	49.9	49.9	0.0
Xanomeline Low Dose		Week 12	95.7	95.7	0.0
Xanomeline Low Dose		Week 16	93.4	95.7	-2.3
Xanomeline Low Dose		Week 2	96.2	95.7	0.5
Xanomeline Low Dose		Week 20	93.9	95.7	-1.8
Xanomeline Low Dose		Week 24	92.1	95.7	-3.6
Xanomeline Low Dose		Week 26	90.7	95.7	-5.0
Xanomeline Low Dose		Week 4	96.6	95.7	0.9
Xanomeline Low Dose		Week 6	94.8	95.7	-0.9
Xanomeline Low Dose		Week 8	94.8	95.7	-0.9
Xanomeline High Dose		Week 12	83.0	80.3	2.7
Xanomeline High Dose		Week 16	81.7	80.3	1.4
Xanomeline High Dose		Week 2	82.1	80.3	1.8
Xanomeline High Dose		Week 20	81.2	80.3	0.9
Xanomeline High Dose		Week 24	82.6	80.3	2.3
Xanomeline High Dose		Week 26	81.7	80.3	1.4
Xanomeline High Dose		Week 4	82.1	80.3	1.8
Xanomeline High Dose		Week 6	82.6	80.3	2.3
Xanomeline High Dose		Week 8	82.6	80.3	2.3
Placebo		Week 12	80.7	81.7	-0.9
Placebo		Week 16	81.7	81.7	0.0
Placebo		Week 2	80.7	81.7	-0.9
Placebo		Week 4	81.2	81.7	-0.5
Placebo		Week 6	79.8	81.7	-1.8
Placebo		Week 8	81.7	81.7	0.0
Xanomeline Low Dose		Week 2	59.4	57.6	1.8
Placebo		Week 2	47.6	47.6	0.0
Placebo		Week 4	49.4	47.6	1.8
Placebo		Week 6	49.9	47.6	2.3
Xanomeline High Dose		Week 2	70.8	71.7	-0.9
Xanomeline High Dose		Week 4	71.7	71.7	0.0
Xanomeline High Dose		Week 6	71.7	71.7	0.0
Xanomeline High Dose		Week 8	70.8	71.7	-0.9
Xanomeline Low Dose		Week 2	47.6	46.7	0.9
Xanomeline Low Dose		Week 4	48.1	46.7	1.4
Xanomeline Low Dose		Week 6	48.5	46.7	1.8
Xanomeline Low Dose		Week 8	47.2	46.7	0.5
Placebo		Week 2	43.1	42.6	0.5
Placebo		Week 4	42.2	42.6	-0.5
Placebo		Week 12	56.7	56.2	0.5
Placebo		Week 16	56.2	56.2	0.0
Placebo		Week 2	56.7	56.2	0.5
Placebo		Week 4	56.7	56.2	0.5
Placebo		Week 6	56.2	56.2	0.0
Placebo		Week 8	55.8	56.2	-0.5
Xanomeline High Dose		Week 12	89.4	89.4	0.0
Xanomeline High Dose		Week 16	87.5	89.4	-1.8
Xanomeline High Dose		Week 2	90.3	89.4	0.9
Xanomeline High Dose		Week 20	88.0	89.4	-1.4
Xanomeline High Dose		Week 24	88.0	89.4	-1.4
Xanomeline High Dose		Week 26	88.5	89.4	-0.9
Xanomeline High Dose		Week 4	90.3	89.4	0.9
Xanomeline High Dose		Week 6	88.9	89.4	-0.5
Xanomeline High Dose		Week 8	90.7	89.4	1.4
Xanomeline Low Dose		Week 12	82.6	82.1	0.5
Xanomeline Low Dose		Week 16	82.1	82.1	0.0
Xanomeline Low Dose		Week 2	82.6	82.1	0.5
Xanomeline Low Dose		Week 20	81.7	82.1	-0.4
Xanomeline Low Dose		Week 4	83.0	82.1	0.9
Xanomeline Low Dose		Week 6	82.1	82.1	0.0
Xanomeline Low Dose		Week 8	82.1	82.1	0.0
Placebo		Week 12	34.0	34.0	0.0
Placebo		Week 16	33.1	34.0	-0.9
Placebo		Week 2	33.1	34.0	-0.9
Placebo		Week 20	33.6	34.0	-0.5
Placebo		Week 24	34.0	34.0	0.0
Placebo		Week 26	34.5	34.0	0.4
Placebo		Week 4	34.5	34.0	0.4
Placebo		Week 6	34.5	34.0	0.4
Placebo		Week 8	34.5	34.0	0.4
Xanomeline Low Dose		Week 12	84.4	84.4	0.0
Xanomeline Low Dose		Week 16	84.8	84.4	0.4
Xanomeline Low Dose		Week 2	84.4	84.4	0.0
Xanomeline Low Dose		Week 4	83.0	84.4	-1.4
Xanomeline Low Dose		Week 6	83.9	84.4	-0.5
Xanomeline Low Dose		Week 8	83.9	84.4	-0.5
Xanomeline High Dose		Week 12	105.2	108.0	-2.7
Xanomeline High Dose		Week 16	105.2	108.0	-2.7
Xanomeline High Dose		Week 2	106.6	108.0	-1.4
Xanomeline High Dose		Week 20	105.7	108.0	-2.3
Xanomeline High Dose		Week 24	105.7	108.0	-2.3
Xanomeline High Dose		Week 26	105.2	108.0	-2.7
Xanomeline High Dose		Week 4	105.7	108.0	-2.3
Xanomeline High Dose		Week 6	104.8	108.0	-3.2
Xanomeline High Dose		Week 8	103.4	108.0	-4.5
Xanomeline High Dose		Week 2	82.1	81.0	1.1
Placebo		Week 12	68.0	69.2	-1.1
Placebo		Week 16	69.4	69.2	0.2
Placebo		Week 2	68.3	69.2	-0.9
Placebo		Week 20	68.7	69.2	-0.5
Placebo		Week 24	68.7	69.2	-0.5
Placebo		Week 26	68.0	69.2	-1.1
Placebo		Week 4	68.0	69.2	-1.1
Placebo		Week 6	66.9	69.2	-2.3
Placebo		Week 8	67.8	69.2	-1.4
Xanomeline Low Dose		Week 2	66.2	64.6	1.6
Xanomeline Low Dose		Week 4	66.5	64.6	1.8
Xanomeline Low Dose		Week 6	64.9	64.6	0.2
Xanomeline Low Dose		Week 8	64.6	64.6	0.0
Xanomeline Low Dose		Week 12	51.3	51.3	0.0
Xanomeline Low Dose		Week 16	51.3	51.3	0.0
Xanomeline Low Dose		Week 2	51.7	51.3	0.5
Xanomeline Low Dose		Week 20	51.7	51.3	0.5
Xanomeline Low Dose		Week 24	52.2	51.3	0.9
Xanomeline Low Dose		Week 26	54.9	51.3	3.6
Xanomeline Low Dose		Week 4	51.3	51.3	0.0
Xanomeline Low Dose		Week 6	51.3	51.3	0.0
Xanomeline Low Dose		Week 8	52.2	51.3	0.9
Xanomeline Low Dose		Week 12	56.9	56.9	0.0
Xanomeline Low Dose		Week 16	59.9	56.9	3.0
Xanomeline Low Dose		Week 2	56.9	56.9	0.0
Xanomeline Low Dose		Week 20	56.9	56.9	0.0
Xanomeline Low Dose		Week 24	56.9	56.9	0.0
Xanomeline Low Dose		Week 26	56.9	56.9	0.0
Xanomeline Low Dose		Week 4	56.9	56.9	0.0
Xanomeline Low Dose		Week 6	56.9	56.9	0.0
Xanomeline Low Dose		Week 8	56.9	56.9	0.0
Xanomeline High Dose		Week 12	54.0	53.1	0.9
Xanomeline High Dose		Week 16	54.4	53.1	1.4
Xanomeline High Dose		Week 2	53.5	53.1	0.5
Xanomeline High Dose		Week 20	53.5	53.1	0.5
Xanomeline High Dose		Week 24	52.6	53.1	-0.5
Xanomeline High Dose		Week 26	54.0	53.1	0.9
Xanomeline High Dose		Week 4	53.5	53.1	0.5
Xanomeline High Dose		Week 6	53.1	53.1	0.0
Xanomeline High Dose		Week 8	54.9	53.1	1.8
Xanomeline High Dose		Week 2	68.0	68.0	0.0
Xanomeline High Dose		Week 4	67.6	68.0	-0.5
Placebo		Week 12	53.5	55.3	-1.8
Placebo		Week 16	53.1	55.3	-2.3
Placebo		Week 2	56.7	55.3	1.4
Placebo		Week 20	50.8	55.3	-4.5
Placebo		Week 24	50.8	55.3	-4.5
Placebo		Week 26	50.4	55.3	-5.0
Placebo		Week 4	56.7	55.3	1.4
Placebo		Week 6	52.6	55.3	-2.7
Placebo		Week 8	54.0	55.3	-1.4
Xanomeline High Dose		Week 12	52.2	52.2	0.0
Xanomeline High Dose		Week 16	52.2	52.2	0.0
Xanomeline High Dose		Week 2	52.2	52.2	0.0
Xanomeline High Dose		Week 20	54.4	52.2	2.3
Xanomeline High Dose		Week 24	54.4	52.2	2.3
Xanomeline High Dose		Week 26	55.3	52.2	3.2
Xanomeline High Dose		Week 4	52.2	52.2	0.0
Xanomeline High Dose		Week 6	52.2	52.2	0.0
Xanomeline High Dose		Week 8	52.2	52.2	0.0
Placebo		Week 12	78.5	77.1	1.4
Placebo		Week 16	76.2	77.1	-0.9
Placebo		Week 2	76.2	77.1	-0.9
Placebo		Week 20	78.9	77.1	1.8
Placebo		Week 24	76.2	77.1	-0.9
Placebo		Week 26	77.1	77.1	0.0
Placebo		Week 4	76.2	77.1	-0.9
Placebo		Week 6	76.2	77.1	-0.9
Placebo		Week 8	78.0	77.1	0.9
Placebo		Week 12	81.7	75.3	6.4
Placebo		Week 16	81.7	75.3	6.4
Placebo		Week 2	75.3	75.3	0.0
Placebo		Week 20	80.7	75.3	5.4
Placebo		Week 24	81.7	75.3	6.4
Placebo		Week 26	78.9	75.3	3.6
Placebo		Week 4	75.3	75.3	0.0
Placebo		Week 6	78.9	75.3	3.6
Placebo		Week 8	78.9	75.3	3.6
Xanomeline Low Dose		Week 12	78.5	78.5	0.0
Xanomeline Low Dose		Week 2	78.5	78.5	0.0
Xanomeline Low Dose		Week 4	78.5	78.5	0.0
Xanomeline Low Dose		Week 6	78.5	78.5	0.0
Xanomeline Low Dose		Week 8	78.5	78.5	0.0
Placebo		Week 12	55.8	54.4	1.4
Placebo		Week 16	54.9	54.4	0.5
Placebo		Week 2	54.4	54.4	0.0
Placebo		Week 20	54.4	54.4	0.0
Placebo		Week 24	54.9	54.4	0.5
Placebo		Week 26	54.9	54.4	0.5
Placebo		Week 4	54.4	54.4	0.0
Placebo		Week 6	55.1	54.4	0.7
Placebo		Week 8	55.8	54.4	1.4
Xanomeline Low Dose		Week 2	53.5	54.4	-0.9
Xanomeline Low Dose		Week 4	53.1	54.4	-1.4
Xanomeline Low Dose		Week 6	55.8	54.4	1.4
Xanomeline Low Dose		Week 8	55.3	54.4	0.9
Xanomeline Low Dose		Week 12	84.8	85.7	-0.9
Xanomeline Low Dose		Week 16	86.9	85.7	1.1
Xanomeline Low Dose		Week 2	85.3	85.7	-0.5
Xanomeline Low Dose		Week 20	86.0	85.7	0.2
Xanomeline Low Dose		Week 24	85.7	85.7	0.0
Xanomeline Low Dose		Week 26	85.3	85.7	-0.5
Xanomeline Low Dose		Week 4	86.2	85.7	0.5
Xanomeline Low Dose		Week 6	84.1	85.7	-1.6
Xanomeline Low Dose		Week 8	84.4	85.7	-1.4
Xanomeline High Dose		Week 12	50.6	49.4	1.1
Xanomeline High Dose		Week 16	50.8	49.4	1.4
Xanomeline High Dose		Week 2	50.6	49.4	1.1
Xanomeline High Dose		Week 20	50.8	49.4	1.4
Xanomeline High Dose		Week 24	49.9	49.4	0.5
Xanomeline High Dose		Week 26	49.9	49.4	0.5
Xanomeline High Dose		Week 4	50.4	49.4	0.9
Xanomeline High Dose		Week 6	50.4	49.4	0.9
Xanomeline High Dose		Week 8	50.4	49.4	0.9
Placebo		Week 12	58.1	57.6	0.5
Placebo		Week 16	57.6	57.6	0.0
Placebo		Week 2	56.7	57.6	-0.9
Placebo		Week 20	57.8	57.6	0.2
Placebo		Week 24	58.5	57.6	0.9
Placebo		Week 26	58.5	57.6	0.9
Placebo		Week 4	58.1	57.6	0.5
Placebo		Week 6	56.7	57.6	-0.9
Placebo		Week 8	57.1	57.6	-0.5
Xanomeline Low Dose		Week 12	56.2	57.6	-1.4
Xanomeline Low Dose		Week 16	57.1	57.6	-0.5
Xanomeline Low Dose		Week 2	56.2	57.6	-1.4
Xanomeline Low Dose		Week 20	57.6	57.6	0.0
Xanomeline Low Dose		Week 24	56.7	57.6	-0.9
Xanomeline Low Dose		Week 26	58.5	57.6	0.9
Xanomeline Low Dose		Week 4	54.9	57.6	-2.7
Xanomeline Low Dose		Week 6	56.7	57.6	-0.9
Xanomeline Low Dose		Week 8	56.7	57.6	-0.9
Xanomeline Low Dose		Week 2	69.4	69.4	0.0
Xanomeline Low Dose		Week 4	68.0	69.4	-1.4
Xanomeline Low Dose		Week 6	68.0	69.4	-1.4
Xanomeline Low Dose		Week 8	72.1	69.4	2.7
Placebo		Week 2	63.5	63.5	0.0
Placebo		Week 4	63.5	63.5	0.0
Placebo		Week 12	49.9	49.4	0.5
Placebo		Week 16	49.9	49.4	0.5
Placebo		Week 2	49.0	49.4	-0.4
Placebo		Week 20	51.3	49.4	1.8
Placebo		Week 24	49.9	49.4	0.5
Placebo		Week 4	49.0	49.4	-0.4
Placebo		Week 6	49.0	49.4	-0.4
Placebo		Week 8	50.4	49.4	0.9
Xanomeline High Dose		Week 2	74.4	75.8	-1.4
Xanomeline High Dose		Week 2	60.3	59.9	0.4
Xanomeline High Dose		Week 4	59.9	59.9	0.0
Xanomeline High Dose		Week 6	59.4	59.9	-0.5
Xanomeline High Dose		Week 8	59.9	59.9	0.0
Placebo		Week 12	71.7	67.1	4.5
Placebo		Week 16	71.2	67.1	4.1
Placebo		Week 2	68.0	67.1	0.9
Placebo		Week 20	69.8	67.1	2.7
Placebo		Week 24	69.0	67.1	1.8
Placebo		Week 4	69.4	67.1	2.3
Placebo		Week 6	70.8	67.1	3.6
Placebo		Week 8	71.7	67.1	4.5
Placebo		Week 12	55.3	54.4	0.9
Placebo		Week 16	55.3	54.4	0.9
Placebo		Week 2	54.9	54.4	0.5
Placebo		Week 20	54.4	54.4	0.0
Placebo		Week 24	55.3	54.4	0.9
Placebo		Week 26	56.5	54.4	2.0
Placebo		Week 4	54.4	54.4	0.0
Placebo		Week 6	54.4	54.4	0.0
Placebo		Week 8	54.9	54.4	0.5
Placebo		Week 12	77.1	79.8	-2.7
Placebo		Week 16	78.9	79.8	-0.9
Placebo		Week 2	80.7	79.8	0.9
Placebo		Week 20	80.5	79.8	0.7
Placebo		Week 24	80.3	79.8	0.5
Placebo		Week 26	80.3	79.8	0.5
Placebo		Week 4	80.3	79.8	0.5
Placebo		Week 6	81.7	79.8	1.8
Placebo		Week 8	80.3	79.8	0.5
Placebo		Week 12	84.4	86.2	-1.8
Placebo		Week 16	85.3	86.2	-0.9
Placebo		Week 2	85.7	86.2	-0.5
Placebo		Week 20	86.2	86.2	0.0
Placebo		Week 24	86.6	86.2	0.5
Placebo		Week 26	87.1	86.2	0.9
Placebo		Week 4	84.4	86.2	-1.8
Placebo		Week 6	84.8	86.2	-1.4
Placebo		Week 8	84.4	86.2	-1.8
Xanomeline Low Dose		Week 12	72.1	72.6	-0.5
Xanomeline Low Dose		Week 2	73.5	72.6	0.9
Xanomeline Low Dose		Week 4	74.4	72.6	1.8
Xanomeline Low Dose		Week 6	72.1	72.6	-0.5
Xanomeline Low Dose		Week 8	72.6	72.6	0.0
Xanomeline High Dose		Week 2	76.7	76.7	0.0
Xanomeline High Dose		Week 4	76.7	76.7	0.0
Xanomeline High Dose		Week 6	75.3	76.7	-1.4
Xanomeline High Dose		Week 8	74.8	76.7	-1.8
Xanomeline Low Dose		Week 2	79.8	80.7	-0.9
Xanomeline Low Dose		Week 4	80.7	80.7	0.0
Xanomeline Low Dose		Week 12	72.6	69.8	2.7
Xanomeline Low Dose		Week 16	71.4	69.8	1.6
Xanomeline Low Dose		Week 2	71.7	69.8	1.8
Xanomeline Low Dose		Week 20	72.1	69.8	2.3
Xanomeline Low Dose		Week 24	70.8	69.8	0.9
Xanomeline Low Dose		Week 26	72.6	69.8	2.7
Xanomeline Low Dose		Week 4	73.0	69.8	3.2
Xanomeline Low Dose		Week 6	73.5	69.8	3.6
Xanomeline Low Dose		Week 8	72.6	69.8	2.7
Placebo		Week 12	54.9	52.6	2.3
Placebo		Week 16	54.9	52.6	2.3
Placebo		Week 2	54.4	52.6	1.8
Placebo		Week 20	53.1	52.6	0.5
Placebo		Week 24	54.9	52.6	2.3
Placebo		Week 26	54.7	52.6	2.0
Placebo		Week 4	54.4	52.6	1.8
Placebo		Week 6	54.4	52.6	1.8
Placebo		Week 8	54.4	52.6	1.8
Xanomeline Low Dose		Week 12	44.0	45.8	-1.8
Xanomeline Low Dose		Week 2	44.9	45.8	-0.9
Xanomeline Low Dose		Week 4	44.5	45.8	-1.4
Xanomeline Low Dose		Week 6	44.0	45.8	-1.8
Xanomeline Low Dose		Week 8	44.9	45.8	-0.9
Xanomeline Low Dose		Week 12	60.3	59.4	0.9
Xanomeline Low Dose		Week 16	61.2	59.4	1.8
Xanomeline Low Dose		Week 2	59.0	59.4	-0.5
Xanomeline Low Dose		Week 20	61.2	59.4	1.8
Xanomeline Low Dose		Week 24	61.2	59.4	1.8
Xanomeline Low Dose		Week 4	59.4	59.4	0.0
Xanomeline Low Dose		Week 6	61.2	59.4	1.8
Xanomeline Low Dose		Week 8	59.9	59.4	0.5
Placebo		Week 12	59.4	59.9	-0.5
Placebo		Week 16	58.5	59.9	-1.4
Placebo		Week 2	59.0	59.9	-0.9
Placebo		Week 20	58.5	59.9	-1.4
Placebo		Week 24	59.0	59.9	-0.9
Placebo		Week 26	59.4	59.9	-0.5
Placebo		Week 4	59.4	59.9	-0.5
Placebo		Week 6	59.4	59.9	-0.5
Placebo		Week 8	59.0	59.9	-0.9
Xanomeline Low Dose		Week 12	62.6	62.6	0.0
Xanomeline Low Dose		Week 16	61.7	62.6	-0.9
Xanomeline Low Dose		Week 2	62.6	62.6	0.0
Xanomeline Low Dose		Week 20	61.7	62.6	-0.9
Xanomeline Low Dose		Week 24	60.8	62.6	-1.8
Xanomeline Low Dose		Week 4	62.6	62.6	0.0
Xanomeline Low Dose		Week 6	62.6	62.6	0.0
Xanomeline Low Dose		Week 8	62.6	62.6	0.0
Placebo		Week 12	82.3	86.2	-3.9
Placebo		Week 16	83.5	86.2	-2.7
Placebo		Week 2	88.0	86.2	1.8
Placebo		Week 20	84.4	86.2	-1.8
Placebo		Week 24	85.3	86.2	-0.9
Placebo		Week 26	86.2	86.2	0.0
Placebo		Week 4	84.4	86.2	-1.8
Placebo		Week 6	83.5	86.2	-2.7
Placebo		Week 8	83.5	86.2	-2.7
Xanomeline High Dose		Week 12	71.7	73.5	-1.8
Xanomeline High Dose		Week 16	73.9	73.5	0.5
Xanomeline High Dose		Week 2	73.5	73.5	0.0
Xanomeline High Dose		Week 4	72.1	73.5	-1.4
Xanomeline High Dose		Week 6	72.1	73.5	-1.4
Xanomeline High Dose		Week 8	72.1	73.5	-1.4
Xanomeline High Dose		Week 2	64.0	64.0	0.0
Xanomeline High Dose		Week 4	64.0	64.0	0.0
Xanomeline Low Dose		Week 2	71.2	71.7	-0.5
Xanomeline Low Dose		Week 4	71.7	71.7	0.0
Xanomeline Low Dose		Week 6	72.3	71.7	0.7
Xanomeline Low Dose		Week 8	72.6	71.7	0.9
Placebo		Week 2	57.1	58.5	-1.4
Placebo		Week 4	58.5	58.5	0.0
Placebo		Week 6	58.5	58.5	0.0
Xanomeline Low Dose		Week 12	76.4	80.7	-4.3
Xanomeline Low Dose		Week 16	77.3	80.7	-3.4
Xanomeline Low Dose		Week 2	82.1	80.7	1.4
Xanomeline Low Dose		Week 4	80.3	80.7	-0.4
Xanomeline Low Dose		Week 6	77.8	80.7	-2.9
Xanomeline Low Dose		Week 8	78.9	80.7	-1.8
Xanomeline High Dose		Week 12	53.1	54.0	-0.9
Xanomeline High Dose		Week 16	50.8	54.0	-3.2
Xanomeline High Dose		Week 2	54.0	54.0	0.0
Xanomeline High Dose		Week 20	51.7	54.0	-2.3
Xanomeline High Dose		Week 24	51.7	54.0	-2.3
Xanomeline High Dose		Week 26	51.7	54.0	-2.3
Xanomeline High Dose		Week 4	53.8	54.0	-0.2
Xanomeline High Dose		Week 6	53.8	54.0	-0.2
Xanomeline High Dose		Week 8	54.4	54.0	0.5
Xanomeline High Dose		Week 2	70.8	69.4	1.4
Xanomeline High Dose		Week 4	72.1	69.4	2.7
Xanomeline High Dose		Week 6	71.7	69.4	2.3
Xanomeline High Dose		Week 8	72.6	69.4	3.2
Xanomeline High Dose		Week 12	70.3	69.0	1.4
Xanomeline High Dose		Week 16	71.2	69.0	2.3
Xanomeline High Dose		Week 2	69.8	69.0	0.9
Xanomeline High Dose		Week 20	71.7	69.0	2.7
Xanomeline High Dose		Week 24	71.7	69.0	2.7
Xanomeline High Dose		Week 26	63.0	69.0	-5.9
Xanomeline High Dose		Week 4	70.3	69.0	1.4
Xanomeline High Dose		Week 6	71.2	69.0	2.3
Xanomeline High Dose		Week 8	71.4	69.0	2.5
Placebo		Week 12	58.5	57.6	0.9
Placebo		Week 16	57.8	57.6	0.2
Placebo		Week 2	57.6	57.6	0.0
Placebo		Week 20	57.8	57.6	0.2
Placebo		Week 24	58.1	57.6	0.5
Placebo		Week 26	57.1	57.6	-0.5
Placebo		Week 4	57.6	57.6	0.0
Placebo		Week 6	57.1	57.6	-0.5
Placebo		Week 8	59.0	57.6	1.4
Xanomeline High Dose		Week 12	54.4	54.4	0.0
Xanomeline High Dose		Week 16	55.3	54.4	0.9
Xanomeline High Dose		Week 2	55.3	54.4	0.9
Xanomeline High Dose		Week 20	55.3	54.4	0.9
Xanomeline High Dose		Week 24	54.9	54.4	0.5
Xanomeline High Dose		Week 26	54.7	54.4	0.2
Xanomeline High Dose		Week 4	56.2	54.4	1.8
Xanomeline High Dose		Week 6	54.9	54.4	0.5
Xanomeline High Dose		Week 8	54.9	54.4	0.5
Xanomeline Low Dose		Week 12	57.1	55.8	1.4
Xanomeline Low Dose		Week 16	58.1	55.8	2.3
Xanomeline Low Dose		Week 2	54.5	55.8	-1.3
Xanomeline Low Dose		Week 20	58.1	55.8	2.3
Xanomeline Low Dose		Week 24	59.0	55.8	3.2
Xanomeline Low Dose		Week 26	59.0	55.8	3.2
Xanomeline Low Dose		Week 4	56.8	55.8	1.0
Xanomeline Low Dose		Week 6	55.8	55.8	0.0
Xanomeline Low Dose		Week 8	56.7	55.8	0.9
Xanomeline High Dose		Week 12	77.1	44.5	32.7
Xanomeline High Dose		Week 16	77.6	44.5	33.1
Xanomeline High Dose		Week 2	78.9	44.5	34.5
Xanomeline High Dose		Week 20	77.6	44.5	33.1
Xanomeline High Dose		Week 24	77.8	44.5	33.3
Xanomeline High Dose		Week 26	81.4	44.5	37.0
Xanomeline High Dose		Week 4	78.5	44.5	34.0
Xanomeline High Dose		Week 6	79.4	44.5	34.9
Xanomeline High Dose		Week 8	77.6	44.5	33.1
Xanomeline High Dose		Week 12	68.7	68.0	0.7
Xanomeline High Dose		Week 16	68.7	68.0	0.7
Xanomeline High Dose		Week 2	69.0	68.0	0.9
Xanomeline High Dose		Week 20	68.0	68.0	0.0
Xanomeline High Dose		Week 24	68.0	68.0	0.0
Xanomeline High Dose		Week 26	68.0	68.0	0.0
Xanomeline High Dose		Week 4	68.3	68.0	0.2
Xanomeline High Dose		Week 6	67.1	68.0	-0.9
Xanomeline High Dose		Week 8	67.6	68.0	-0.5
Placebo		Week 2	69.0	68.0	0.9
Placebo		Week 4	69.0	68.0	0.9
Placebo		Week 6	69.0	68.0	0.9
Placebo		Week 8	68.0	68.0	0.0
Placebo		Week 2	59.0	58.1	0.9
Placebo		Week 4	58.0	58.1	-0.1
Placebo		Week 6	59.0	58.1	0.9
Placebo		Week 8	57.8	58.1	-0.3
Xanomeline High Dose		Week 12	82.6	81.3	1.3
Xanomeline High Dose		Week 16	83.5	81.3	2.2
Xanomeline High Dose		Week 2	81.2	81.3	-0.1
Xanomeline High Dose		Week 20	86.6	81.3	5.3
Xanomeline High Dose		Week 4	83.0	81.3	1.7
Xanomeline High Dose		Week 6	84.8	81.3	3.5
Xanomeline High Dose		Week 8	83.5	81.3	2.2
Xanomeline Low Dose		Week 12	46.0	47.2	-1.1
Xanomeline Low Dose		Week 16	45.8	47.2	-1.4
Xanomeline Low Dose		Week 2	48.1	47.2	0.9
Xanomeline Low Dose		Week 20	46.0	47.2	-1.1
Xanomeline Low Dose		Week 24	45.5	47.2	-1.6
Xanomeline Low Dose		Week 4	47.4	47.2	0.2
Xanomeline Low Dose		Week 6	47.2	47.2	0.0
Xanomeline Low Dose		Week 8	46.3	47.2	-0.9
Xanomeline Low Dose		Week 2	50.4	50.4	0.0
Xanomeline Low Dose		Week 4	51.3	50.4	0.9
Xanomeline High Dose		Week 12	83.2	80.3	2.9
Xanomeline High Dose		Week 16	82.6	80.3	2.3
Xanomeline High Dose		Week 2	81.2	80.3	0.9
Xanomeline High Dose		Week 20	80.8	80.3	0.5
Xanomeline High Dose		Week 4	83.0	80.3	2.7
Xanomeline High Dose		Week 6	82.1	80.3	1.8
Xanomeline High Dose		Week 8	83.9	80.3	3.6
Placebo		Week 12	65.4	65.8	-0.4
Placebo		Week 16	65.3	65.8	-0.5
Placebo		Week 2	67.6	65.8	1.8
Placebo		Week 20	66.7	65.8	0.9
Placebo		Week 24	64.9	65.8	-0.9
Placebo		Week 26	65.3	65.8	-0.5
Placebo		Week 4	65.8	65.8	0.0
Placebo		Week 6	66.2	65.8	0.5
Placebo		Week 8	65.9	65.8	0.1
Placebo		Week 12	54.9	54.9	0.0
Placebo		Week 16	54.4	54.9	-0.5
Placebo		Week 20	54.9	54.9	0.0
Placebo		Week 24	54.8	54.9	-0.1
Placebo		Week 4	54.4	54.9	-0.5
Placebo		Week 8	52.6	54.9	-2.3
Xanomeline Low Dose		Week 2	59.0	57.6	1.4
Placebo		Week 12	67.6	66.2	1.4
Placebo		Week 2	66.7	66.2	0.5
Placebo		Week 4	66.7	66.2	0.5
Placebo		Week 6	68.0	66.2	1.7
Placebo		Week 8	66.7	66.2	0.5
Xanomeline Low Dose		Week 12	56.7	58.5	-1.8
Xanomeline Low Dose		Week 16	57.6	58.5	-0.9
Xanomeline Low Dose		Week 2	58.5	58.5	0.0
Xanomeline Low Dose		Week 4	57.5	58.5	-1.0
Xanomeline Low Dose		Week 6	58.1	58.5	-0.4
Xanomeline Low Dose		Week 8	58.1	58.5	-0.4
Xanomeline Low Dose		Week 12	83.0	82.1	0.9
Xanomeline Low Dose		Week 16	83.5	82.1	1.4
Xanomeline Low Dose		Week 2	82.8	82.1	0.7
Xanomeline Low Dose		Week 20	80.7	82.1	-1.4
Xanomeline Low Dose		Week 24	84.4	82.1	2.3
Xanomeline Low Dose		Week 26	85.3	82.1	3.2
Xanomeline Low Dose		Week 4	82.3	82.1	0.2
Xanomeline Low Dose		Week 6	83.1	82.1	1.0
Xanomeline Low Dose		Week 8	83.5	82.1	1.4
Xanomeline High Dose		Week 2	65.0	63.5	1.5
Xanomeline High Dose		Week 4	66.7	63.5	3.2
Xanomeline High Dose		Week 6	63.5	63.5	0.0
Xanomeline High Dose		Week 8	63.5	63.5	0.0
Placebo		Week 12	59.9	58.5	1.4
Placebo		Week 16	61.7	58.5	3.2
Placebo		Week 2	59.0	58.5	0.5
Placebo		Week 20	62.1	58.5	3.6
Placebo		Week 24	64.4	58.5	5.9
Placebo		Week 26	62.7	58.5	4.2
Placebo		Week 4	60.8	58.5	2.3
Placebo		Week 6	60.1	58.5	1.6
Placebo		Week 8	59.9	58.5	1.4
Xanomeline High Dose		Week 2	66.7	66.7	0.0
Xanomeline High Dose		Week 4	67.1	66.7	0.4
Xanomeline High Dose		Week 6	65.8	66.7	-0.9
Xanomeline High Dose		Week 8	66.7	66.7	0.0
Xanomeline High Dose		Week 2	50.4	51.7	-1.3
Xanomeline High Dose		Week 4	51.0	51.7	-0.7
Xanomeline High Dose		Week 6	50.7	51.7	-1.0

On-treatment records: ONTRTFL = 'Y'. Derived records (DTYPE non-missing) are excluded.

Value, Baseline, and Change from Baseline are in original units (VSSTRESU).

Sorted by parameter, treatment arm, subject, and visit number.

Parameters: BMI (kg/m²), BSA (m²), DIABP/SYSBP (mmHg), HEIGHT (cm), MAP (mmHg), PULSE (beats/min), TEMP (^°C), WEIGHT (kg).

/opt/quarto/share/rmd/rmd.R 01APR2026 09:51:10