Cards ARD for demographics (flat ARD companion)

The same demographics summary as cdisc_saf_demo, but in the long Analysis Results Data (ARD) format produced by cards::ard_stack(). One row per (treatment arm, variable, statistic). Shipped as a teaching dataset that shows the upstream shape users typically have when they start from cards. Convert it to the wide form tabular() accepts via pivot_across() — tabular itself does not consume the long ARD format, since pre-summarised wide data is the package boundary.

Usage

cdisc_saf_demo_ard

Format

A card-classed tibble with columns group1, group1_level, variable, variable_level, context, stat_name, stat_label, stat. group1 == "TRT01A" and group1_level carries the original pharmaverseadam arm labels ("Placebo", "Xanomeline Low Dose", "Xanomeline High Dose"). cards::ard_stack(.overall = TRUE) adds overall rows with group1_level = NA; pivot_across() renders those into a Total column.

Source

Derived in data-raw/bundle-demo.R via cards::ard_stack(.by = "TRT01A", .overall = TRUE) over pharmaverseadam::adsl.

Details

Continuous variables: AGE, WEIGHT, HEIGHT, BMI (each emitting N, mean, sd, median, p25, p75, min, max). Categorical variables: AGEGR1, SEX, RACE, ETHNIC, BMI_CAT (each emitting n, N, p).

This is the package's canonical flat ARD demo. Its hierarchical counterpart is cdisc_saf_aesocpt_ard; together they cover both shapes pivot_across() must handle.

See also

pivot_across() for the long-to-wide bridge; cdisc_saf_demo for the wide companion.

Examples

# 95% demographics pattern: cards ARD -> wide -> rendered table.
n <- stats::setNames(cdisc_saf_n$n, cdisc_saf_n$arm_short)
cdisc_saf_demo_ard |>
  pivot_across(
    statistic = list(
      continuous  = "{mean} ({sd})",
      categorical = "{n} ({p}%)"
    ),
    label = c(AGE = "Age (years)", SEX = "Sex", RACE = "Race")
  ) |>
  tabular(
    titles = c(
      "Table 14.1.1",
      "Demographics",
      "Safety Population"
    )
  )
 
Table 14.1.1
Demographics
Safety Population
 

variable
stat_label
Placebo
Xanomeline High Dose
Xanomeline Low Dose
Total
Age (years)
AGE
75.2 (8.59)
73.8 (7.94)
76.0 (8.11)
75.1 (8.25)
WEIGHT
WEIGHT
62.8 (12.77)
69.5 (14.35)
68.0 (14.50)
66.6 (14.13)
HEIGHT
HEIGHT
162.6 (11.52)
165.9 (10.28)
163.7 (10.30)
163.9 (10.76)
BMI
BMI
23.6 (3.67)
25.2 (3.97)
25.2 (4.40)
24.7 (4.09)
AGEGR1
  18-64
14 (16%)
11 (15%)
8 (8%)
33 (13%)
AGEGR1
  >64
72 (84%)
61 (85%)
88 (92%)
221 (87%)
Sex
  F
53 (62%)
35 (49%)
55 (57%)
143 (56%)
Sex
  M
33 (38%)
37 (51%)
41 (43%)
111 (44%)
Race
  WHITE
78 (91%)
62 (86%)
90 (94%)
230 (91%)
Race
  BLACK OR AFRICAN AMERICAN
8 (9%)
9 (12%)
6 (6%)
23 (9%)
Race
  ASIAN
0
0
0
0
Race
  AMERICAN INDIAN OR ALASKA NATIVE
0
1 (1%)
0
1 (0%)
ETHNIC
  HISPANIC OR LATINO
3 (3%)
3 (4%)
6 (6%)
12 (5%)
ETHNIC
  NOT HISPANIC OR LATINO
83 (97%)
69 (96%)
90 (94%)
242 (95%)
ETHNIC
  NOT REPORTED
0
0
0
0
BMI_CAT
  Underweight (<18.5)
3 (3%)
1 (1%)
4 (4%)
8 (3%)
BMI_CAT
  Normal (18.5-24.9)
57 (66%)
39 (54%)
46 (48%)
142 (56%)
BMI_CAT
  Overweight (25-29.9)
20 (23%)
23 (32%)
32 (34%)
75 (30%)
BMI_CAT
  Obese (>=30)
6 (7%)
9 (12%)
13 (14%)
28 (11%)